FTSY - ECOLI - GREMLIN Contacts

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FTSY - Signal recognition particle receptor FtsY

UniProt:	P10121	Sequences: MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10346
Length:	497 (413)
Sequences:	1956 (1659)
Seq/√Len:	81.6

ECOLI - FTSY SRP54
BACSU - FTSY FLHF SRP54
HALSA - Q9HMN3 SRP54
SULSO - Q980G1 SRP54

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
370_A	374_R	8.499	1.00
344_G	351_V	7.784	1.00
395_E	398_K	5.350	1.00
416_M	444_T	5.073	1.00
325_M	376_I	3.898	1.00
317_F	378_V	2.795	1.00
247_K	462_D	2.759	1.00
193_E	201_R	2.718	1.00
141_A	145_A	2.676	1.00
325_M	350_P	2.595	1.00
432_K	463_Q	2.512	1.00
327_A	367_A	2.392	1.00
88_A	94_P	2.381	1.00
435_H	440_L	2.363	1.00
246_R	250_T	2.334	1.00
172_P	176_E	2.284	1.00
365_F	369_Q	2.268	1.00
175_E	179_P	2.228	1.00
157_T	163_A	2.216	1.00
173_P	177_E	2.215	1.00
272_K	490_E	2.147	1.00
113_P	117_D	2.119	1.00
432_K	436_E	2.041	1.00
110_E	114_L	2.033	1.00
251_N	274_E	1.987	1.00
126_E	129_Q	1.981	1.00
169_M	173_P	1.928	1.00
355_H	358_A	1.921	1.00
88_A	92_A	1.899	1.00
113_P	116_E	1.897	1.00
89_E	92_A	1.863	1.00
155_L	161_A	1.842	1.00
133_E	151_T	1.838	1.00
138_V	141_A	1.834	1.00
92_A	95_E	1.832	1.00
325_M	379_L	1.788	1.00
244_T	462_D	1.781	1.00
245_T	249_I	1.767	1.00
123_V	129_Q	1.754	1.00
98_V	104_P	1.754	1.00
145_A	149_E	1.753	1.00
388_Q	401_V	1.752	1.00
445_L	457_I	1.750	1.00
87_E	91_V	1.747	1.00
90_V	94_P	1.716	1.00
318_E	348_N	1.715	1.00
123_V	126_E	1.715	1.00
352_I	370_A	1.714	1.00
93_Q	100_E	1.682	1.00
94_P	101_T	1.667	1.00
84_A	88_A	1.651	1.00
296_I	380_I	1.642	1.00
132_A	144_E	1.637	1.00
91_V	95_E	1.630	1.00
138_V	144_E	1.613	1.00
168_V	171_V	1.601	1.00
369_Q	407_L	1.584	1.00
150_I	156_E	1.583	1.00
138_V	143_E	1.577	1.00
140_A	152_D	1.574	1.00
210_L	213_G	1.570	1.00
86_P	92_A	1.566	1.00
86_P	91_V	1.564	1.00
108_E	111_E	1.563	1.00
364_I	381_A	1.553	1.00
341_Q	353_A	1.551	1.00
110_E	113_P	1.547	1.00
109_R	115_P	1.546	1.00
315_R	477_I	1.531	0.99
137_I	142_E	1.526	0.99
171_V	177_E	1.521	0.99
372_K	407_L	1.503	0.99
401_V	405_K	1.493	0.99
82_E	86_P	1.492	0.99
129_Q	135_V	1.488	0.99
161_A	165_E	1.481	0.99
154_E	158_A	1.467	0.99
173_P	179_P	1.460	0.99
134_T	137_I	1.459	0.99
298_M	388_Q	1.450	0.99
136_E	144_E	1.450	0.99
476_R	484_K	1.449	0.99
136_E	142_E	1.445	0.99
146_A	149_E	1.442	0.99
431_A	464_F	1.436	0.99
316_Q	482_P	1.435	0.99
128_W	131_E	1.430	0.99
174_A	178_Q	1.429	0.99
443_I	460_V	1.428	0.99
344_G	350_P	1.419	0.99
276_G	486_D	1.419	0.99
132_A	135_V	1.416	0.99
247_K	251_N	1.414	0.99
144_E	148_E	1.409	0.99
165_E	173_P	1.408	0.99
168_V	174_A	1.394	0.99
126_E	133_E	1.391	0.99
97_V	150_I	1.387	0.99
153_E	159_L	1.385	0.99
347_N	477_I	1.383	0.99
94_P	98_V	1.377	0.99
94_P	100_E	1.366	0.99
174_A	177_E	1.365	0.99
160_A	164_A	1.363	0.99
128_W	132_A	1.340	0.99
108_E	120_A	1.339	0.99
141_A	144_E	1.337	0.99
113_P	125_P	1.332	0.99
146_A	154_E	1.330	0.99
121_E	130_A	1.326	0.98
153_E	163_A	1.325	0.98
194_G	197_A	1.316	0.98
100_E	172_P	1.304	0.98
129_Q	132_A	1.302	0.98
93_Q	108_E	1.298	0.98
368_I	407_L	1.287	0.98
123_V	128_W	1.278	0.98
98_V	102_P	1.277	0.98
109_R	116_E	1.274	0.98
298_M	416_M	1.262	0.98
101_T	104_P	1.262	0.98
114_L	117_D	1.260	0.98
91_V	94_P	1.259	0.98
164_A	168_V	1.258	0.98
105_V	108_E	1.255	0.98
88_A	93_Q	1.255	0.98
140_A	158_A	1.250	0.98
158_A	166_E	1.248	0.98
143_E	150_I	1.246	0.98
168_V	173_P	1.245	0.98
181_E	185_Q	1.244	0.98
99_E	102_P	1.240	0.98
129_Q	133_E	1.239	0.98
139_E	147_K	1.237	0.98
147_K	150_I	1.228	0.97
352_I	374_R	1.219	0.97
151_T	155_L	1.218	0.97
215_I	219_R	1.216	0.97
86_P	90_V	1.212	0.97
484_K	487_D	1.200	0.97
141_A	149_E	1.199	0.97
95_E	101_T	1.193	0.97
341_Q	345_Q	1.193	0.97
315_R	319_Q	1.189	0.97
149_E	153_E	1.189	0.97
91_V	107_I	1.189	0.97
156_E	166_E	1.188	0.97
152_D	170_V	1.181	0.97
118_V	128_W	1.180	0.97
170_V	173_P	1.180	0.97
121_E	124_S	1.179	0.97
161_A	167_A	1.175	0.97
168_V	177_E	1.171	0.97
371_A	379_L	1.168	0.97
162_E	165_E	1.168	0.97
419_I	489_I	1.160	0.96
165_E	175_E	1.159	0.96
108_E	114_L	1.158	0.96
141_A	147_K	1.152	0.96
143_E	147_K	1.151	0.96
138_V	142_E	1.150	0.96
354_Q	366_D	1.147	0.96
126_E	134_T	1.146	0.96
138_V	148_E	1.143	0.96
142_E	145_A	1.141	0.96
155_L	158_A	1.141	0.96
100_E	104_P	1.139	0.96
149_E	155_L	1.136	0.96
99_E	107_I	1.136	0.96
152_D	156_E	1.135	0.96
90_V	93_Q	1.129	0.96
89_E	93_Q	1.129	0.96
109_R	112_L	1.119	0.96
109_R	114_L	1.117	0.96
140_A	146_A	1.114	0.96
329_G	364_I	1.112	0.95
96_P	99_E	1.108	0.95
138_V	146_A	1.106	0.95
84_A	91_V	1.104	0.95
225_D	253_T	1.103	0.95
119_N	125_P	1.100	0.95
92_A	128_W	1.096	0.95
88_A	102_P	1.095	0.95
142_E	159_L	1.092	0.95
163_A	171_V	1.092	0.95
147_K	151_T	1.090	0.95
123_V	139_E	1.086	0.95
171_V	175_E	1.086	0.95
125_P	133_E	1.085	0.95
255_G	274_E	1.083	0.95
144_E	147_K	1.080	0.95
109_R	113_P	1.075	0.95
84_A	87_E	1.073	0.95
154_E	166_E	1.073	0.95
87_E	90_V	1.072	0.94
137_I	141_A	1.067	0.94
217_L	221_K	1.067	0.94
139_E	150_I	1.067	0.94
82_E	85_Q	1.067	0.94
81_S	91_V	1.062	0.94
96_P	108_E	1.061	0.94
169_M	175_E	1.060	0.94
152_D	160_A	1.058	0.94
138_V	160_A	1.055	0.94
139_E	145_A	1.041	0.94
117_D	154_E	1.040	0.94
81_S	85_Q	1.036	0.93
387_L	425_Q	1.035	0.93
159_L	163_A	1.035	0.93
84_A	110_E	1.034	0.93
170_V	174_A	1.032	0.93
103_E	112_L	1.028	0.93
316_Q	470_Y	1.028	0.93
137_I	161_A	1.023	0.93
159_L	164_A	1.021	0.93
127_E	130_A	1.020	0.93
133_E	139_E	1.014	0.93
435_H	439_G	1.013	0.93
90_V	115_P	1.012	0.93
84_A	89_E	1.009	0.93
138_V	151_T	0.997	0.92
105_V	113_P	0.995	0.92
88_A	97_V	0.981	0.91
130_A	133_E	0.978	0.91
143_E	153_E	0.969	0.91
91_V	102_P	0.968	0.91
149_E	152_D	0.964	0.91
165_E	171_V	0.961	0.91
123_V	127_E	0.960	0.91
96_P	102_P	0.958	0.90
93_Q	96_P	0.956	0.90
151_T	154_E	0.956	0.90
166_E	173_P	0.952	0.90
156_E	161_A	0.952	0.90
138_V	150_I	0.949	0.90
173_P	176_E	0.949	0.90
116_E	162_E	0.944	0.90
128_W	133_E	0.940	0.90
256_A	267_L	0.938	0.89
203_L	206_T	0.936	0.89
160_A	166_E	0.934	0.89
104_P	107_I	0.932	0.89
83_K	96_P	0.930	0.89
81_S	86_P	0.929	0.89
274_E	277_E	0.918	0.88
81_S	93_Q	0.916	0.88
106_A	109_R	0.915	0.88
440_L	443_I	0.913	0.88
314_A	326_L	0.912	0.88
107_I	137_I	0.910	0.88
164_A	169_M	0.908	0.88
162_E	174_A	0.907	0.88
87_E	97_V	0.903	0.88
155_L	162_E	0.901	0.88
139_E	142_E	0.900	0.87
94_P	97_V	0.899	0.87
92_A	96_P	0.893	0.87
489_I	494_A	0.892	0.87
135_V	147_K	0.891	0.87
88_A	91_V	0.890	0.87
93_Q	98_V	0.889	0.87
155_L	160_A	0.889	0.87
153_E	156_E	0.887	0.87
156_E	169_M	0.887	0.87
223_I	228_F	0.886	0.87
121_E	126_E	0.885	0.87
164_A	179_P	0.884	0.87
117_D	166_E	0.882	0.86
415_V	439_G	0.878	0.86
165_E	168_V	0.878	0.86
255_G	270_L	0.878	0.86
148_E	152_D	0.876	0.86
157_T	161_A	0.876	0.86
157_T	165_E	0.875	0.86
149_E	159_L	0.875	0.86
111_E	131_E	0.870	0.86
127_E	136_E	0.870	0.86
146_A	158_A	0.870	0.86
117_D	122_A	0.868	0.85
143_E	148_E	0.868	0.85
101_T	107_I	0.868	0.85
82_E	89_E	0.866	0.85
112_L	151_T	0.866	0.85
113_P	119_N	0.864	0.85
284_E	287_N	0.864	0.85
146_A	151_T	0.860	0.85
104_P	113_P	0.858	0.85
122_A	125_P	0.858	0.85
102_P	106_A	0.857	0.85
88_A	100_E	0.856	0.85
85_Q	101_T	0.854	0.85
108_E	112_L	0.853	0.84
155_L	165_E	0.852	0.84
100_E	103_E	0.849	0.84
171_V	174_A	0.847	0.84
132_A	148_E	0.847	0.84
145_A	151_T	0.844	0.84
112_L	115_P	0.843	0.84
109_R	164_A	0.842	0.84
163_A	167_A	0.841	0.84
234_Q	268_Y	0.837	0.83
226_D	230_E	0.836	0.83
150_I	158_A	0.835	0.83
137_I	140_A	0.832	0.83
131_E	134_T	0.831	0.83
145_A	153_E	0.829	0.83
86_P	102_P	0.827	0.83
192_K	196_F	0.825	0.82
218_F	222_K	0.823	0.82
89_E	94_P	0.823	0.82
85_Q	92_A	0.822	0.82
260_Q	270_L	0.821	0.82
151_T	157_T	0.820	0.82
96_P	100_E	0.819	0.82
259_K	273_E	0.818	0.82
84_A	94_P	0.818	0.82
176_E	180_V	0.814	0.82
116_E	123_V	0.813	0.82
89_E	95_E	0.811	0.81
123_V	137_I	0.810	0.81
82_E	87_E	0.810	0.81
296_I	378_V	0.808	0.81
82_E	88_A	0.808	0.81
110_E	148_E	0.807	0.81
111_E	117_D	0.805	0.81
173_P	178_Q	0.800	0.80
154_E	168_V	0.799	0.80
97_V	124_S	0.799	0.80
90_V	105_V	0.798	0.80
85_Q	93_Q	0.798	0.80
182_E	185_Q	0.795	0.80
90_V	97_V	0.794	0.80
163_A	179_P	0.793	0.80
103_E	107_I	0.793	0.80
187_Q	190_P	0.792	0.80
128_W	135_V	0.790	0.80
90_V	98_V	0.788	0.79
96_P	148_E	0.788	0.79
298_M	444_T	0.783	0.79
86_P	89_E	0.782	0.79
116_E	128_W	0.781	0.79
97_V	107_I	0.779	0.79
86_P	95_E	0.779	0.79
391_S	395_E	0.778	0.79
156_E	174_A	0.776	0.78
87_E	115_P	0.775	0.78
164_A	173_P	0.772	0.78
114_L	176_E	0.771	0.78
136_E	148_E	0.770	0.78
90_V	95_E	0.769	0.78
109_R	119_N	0.769	0.78
142_E	156_E	0.769	0.78
138_V	154_E	0.769	0.78
390_K	445_L	0.767	0.78
83_K	91_V	0.767	0.78
323_S	376_I	0.766	0.78
163_A	169_M	0.765	0.77
109_R	149_E	0.765	0.77
183_I	186_E	0.763	0.77
170_V	175_E	0.760	0.77
419_I	431_A	0.759	0.77
140_A	144_E	0.759	0.77
166_E	169_M	0.758	0.77
133_E	143_E	0.758	0.77
168_V	178_Q	0.756	0.77
147_K	153_E	0.755	0.77
81_S	84_A	0.754	0.76
127_E	139_E	0.752	0.76
119_N	139_E	0.752	0.76
88_A	103_E	0.749	0.76
84_A	96_P	0.749	0.76
208_E	212_S	0.749	0.76
327_A	379_L	0.745	0.76
87_E	93_Q	0.745	0.76
181_E	184_A	0.744	0.75
172_P	179_P	0.742	0.75
124_S	128_W	0.741	0.75
283_D	286_L	0.740	0.75
90_V	99_E	0.740	0.75
91_V	98_V	0.738	0.75
125_P	130_A	0.738	0.75
341_Q	351_V	0.735	0.75
240_V	278_I	0.733	0.74
90_V	153_E	0.733	0.74
123_V	131_E	0.731	0.74
131_E	138_V	0.730	0.74
156_E	170_V	0.729	0.74
159_L	165_E	0.728	0.74
159_L	181_E	0.728	0.74
123_V	142_E	0.725	0.74
92_A	101_T	0.724	0.73
159_L	167_A	0.723	0.73
82_E	106_A	0.722	0.73
183_I	189_K	0.721	0.73
317_F	400_I	0.720	0.73
110_E	133_E	0.717	0.73
275_M	361_A	0.715	0.73
216_S	219_R	0.714	0.72
83_K	110_E	0.714	0.72
120_A	130_A	0.712	0.72
102_P	117_D	0.710	0.72
125_P	131_E	0.710	0.72
416_M	442_G	0.709	0.72
120_A	124_S	0.709	0.72
368_I	379_L	0.708	0.72
160_A	165_E	0.708	0.72
83_K	97_V	0.706	0.72
171_V	179_P	0.706	0.72
137_I	143_E	0.706	0.72
369_Q	373_A	0.702	0.71
195_F	199_L	0.701	0.71
143_E	160_A	0.700	0.71
120_A	123_V	0.699	0.71
134_T	161_A	0.699	0.71
124_S	135_V	0.699	0.71
88_A	96_P	0.698	0.71
84_A	99_E	0.697	0.71
130_A	145_A	0.696	0.71
142_E	148_E	0.696	0.71
84_A	93_Q	0.695	0.70
106_A	110_E	0.694	0.70
83_K	87_E	0.693	0.70
226_D	229_E	0.693	0.70
94_P	99_E	0.693	0.70
91_V	157_T	0.692	0.70
261_L	266_A	0.689	0.70
118_V	130_A	0.689	0.70
84_A	92_A	0.688	0.70
280_A	486_D	0.688	0.70
114_L	134_T	0.686	0.69
121_E	141_A	0.684	0.69
106_A	135_V	0.684	0.69
137_I	147_K	0.683	0.69
221_K	224_D	0.682	0.69
98_V	101_T	0.681	0.69
153_E	157_T	0.681	0.69
184_A	188_E	0.679	0.69
132_A	138_V	0.678	0.69
97_V	104_P	0.676	0.68
131_E	171_V	0.676	0.68
92_A	102_P	0.675	0.68
104_P	149_E	0.675	0.68
90_V	116_E	0.673	0.68
155_L	159_L	0.673	0.68
108_E	123_V	0.672	0.68
90_V	102_P	0.671	0.68
153_E	167_A	0.668	0.67
144_E	154_E	0.668	0.67
174_A	179_P	0.667	0.67
85_Q	90_V	0.664	0.67
131_E	157_T	0.664	0.67
125_P	129_Q	0.662	0.67
142_E	146_A	0.662	0.67
326_L	344_G	0.661	0.67
142_E	164_A	0.660	0.66
86_P	105_V	0.660	0.66
256_A	418_T	0.660	0.66
143_E	163_A	0.653	0.66
150_I	153_E	0.653	0.66
164_A	172_P	0.648	0.65
342_V	345_Q	0.648	0.65
324_V	377_D	0.648	0.65
389_N	401_V	0.647	0.65
106_A	112_L	0.646	0.65
104_P	134_T	0.646	0.65
117_D	156_E	0.646	0.65
255_G	277_E	0.644	0.65
461_A	468_I	0.644	0.65
429_S	433_L	0.643	0.64
247_K	273_E	0.643	0.64
154_E	162_E	0.641	0.64
135_V	138_V	0.640	0.64
443_I	456_V	0.639	0.64
247_K	255_G	0.639	0.64
108_E	172_P	0.637	0.64
89_E	101_T	0.636	0.64
82_E	105_V	0.634	0.63
139_E	143_E	0.634	0.63
326_L	468_I	0.632	0.63
292_A	436_E	0.632	0.63
168_V	172_P	0.632	0.63
165_E	170_V	0.631	0.63
83_K	107_I	0.631	0.63
109_R	123_V	0.631	0.63
133_E	137_I	0.631	0.63
138_V	149_E	0.630	0.63
219_R	222_K	0.630	0.63
119_N	122_A	0.629	0.63
143_E	149_E	0.629	0.63
117_D	130_A	0.629	0.63
96_P	112_L	0.627	0.63
82_E	94_P	0.623	0.62
158_A	164_A	0.620	0.62
103_E	109_R	0.620	0.62
99_E	105_V	0.619	0.62
100_E	106_A	0.619	0.62
91_V	99_E	0.618	0.61
123_V	130_A	0.618	0.61
93_Q	97_V	0.618	0.61
103_E	118_V	0.617	0.61
294_F	460_V	0.616	0.61
120_A	150_I	0.615	0.61
108_E	157_T	0.615	0.61
147_K	152_D	0.615	0.61
146_A	163_A	0.613	0.61
139_E	144_E	0.611	0.61
142_E	150_I	0.610	0.60
127_E	133_E	0.609	0.60
392_H	422_S	0.606	0.60
103_E	148_E	0.606	0.60
170_V	176_E	0.606	0.60
171_V	183_I	0.605	0.60
138_V	145_A	0.605	0.60
128_W	143_E	0.605	0.60
83_K	89_E	0.605	0.60
323_S	350_P	0.605	0.60
135_V	165_E	0.604	0.60
115_P	131_E	0.604	0.60
338_E	440_L	0.603	0.60
149_E	154_E	0.600	0.59
212_S	259_K	0.600	0.59
110_E	118_V	0.599	0.59
148_E	163_A	0.598	0.59
202_S	206_T	0.596	0.59
180_V	183_I	0.594	0.58
167_A	177_E	0.594	0.58
95_E	124_S	0.592	0.58
175_E	181_E	0.592	0.58
137_I	148_E	0.591	0.58
97_V	109_R	0.590	0.58
162_E	172_P	0.590	0.58
106_A	111_E	0.589	0.58
121_E	125_P	0.589	0.58
95_E	104_P	0.589	0.58
87_E	92_A	0.588	0.58
276_G	490_E	0.588	0.58
106_A	159_L	0.585	0.57
360_S	400_I	0.585	0.57
204_L	400_I	0.584	0.57
161_A	166_E	0.584	0.57
156_E	180_V	0.584	0.57
163_A	178_Q	0.583	0.57
122_A	143_E	0.582	0.57
97_V	113_P	0.582	0.57
94_P	165_E	0.581	0.57
102_P	122_A	0.581	0.57
106_A	142_E	0.580	0.57
121_E	145_A	0.580	0.57
88_A	146_A	0.579	0.56
129_Q	145_A	0.579	0.56
82_E	97_V	0.578	0.56
107_I	122_A	0.577	0.56
89_E	97_V	0.574	0.56
127_E	146_A	0.573	0.56
124_S	168_V	0.573	0.56
128_W	134_T	0.571	0.55
337_V	356_T	0.569	0.55
93_Q	106_A	0.569	0.55
107_I	113_P	0.569	0.55
86_P	99_E	0.564	0.55
136_E	147_K	0.564	0.55
166_E	172_P	0.563	0.54
105_V	110_E	0.562	0.54
316_Q	320_Q	0.560	0.54
207_K	210_L	0.558	0.54
107_I	110_E	0.558	0.54
161_A	177_E	0.557	0.54
159_L	171_V	0.554	0.53
271_L	491_A	0.554	0.53
162_E	167_A	0.554	0.53
97_V	102_P	0.553	0.53
143_E	151_T	0.553	0.53
111_E	136_E	0.551	0.53
175_E	178_Q	0.549	0.53
127_E	135_V	0.548	0.52
241_G	425_Q	0.542	0.52
171_V	176_E	0.542	0.52
176_E	182_E	0.541	0.52
129_Q	143_E	0.540	0.51
131_E	135_V	0.539	0.51
122_A	181_E	0.538	0.51
434_F	472_G	0.535	0.51
207_K	214_F	0.534	0.51
81_S	88_A	0.531	0.50
111_E	126_E	0.531	0.50
244_T	418_T	0.530	0.50
384_A	393_L	0.530	0.50
227_L	279_L	0.530	0.50
215_I	218_F	0.530	0.50
359_D	399_K	0.529	0.50
88_A	105_V	0.529	0.50
141_A	153_E	0.529	0.50
162_E	166_E	0.528	0.50
124_S	130_A	0.528	0.50
126_E	152_D	0.528	0.50
244_T	278_I	0.528	0.50
111_E	146_A	0.528	0.50
98_V	161_A	0.527	0.50
138_V	156_E	0.526	0.50
270_L	418_T	0.524	0.49
93_Q	113_P	0.523	0.49
210_L	230_E	0.522	0.49
108_E	138_V	0.522	0.49
103_E	108_E	0.521	0.49
136_E	168_V	0.519	0.49
299_V	438_V	0.519	0.49
424_G	427_A	0.519	0.49
147_K	157_T	0.518	0.48
101_T	111_E	0.517	0.48
91_V	97_V	0.517	0.48
130_A	139_E	0.515	0.48
428_V	464_F	0.510	0.47
240_V	243_E	0.509	0.47
81_S	100_E	0.508	0.47
84_A	102_P	0.508	0.47
148_E	151_T	0.506	0.47
82_E	136_E	0.506	0.47
115_P	130_A	0.506	0.47
126_E	166_E	0.505	0.47
161_A	175_E	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2yhsA	1	0.6197	100	0.39	Contact Map
2og2A	1	0.6016	100	0.515	Contact Map
1vmaA	1	0.5915	100	0.516	Contact Map
3b9qA	1	0.5915	100	0.543	Contact Map
4c7oA	1	0.5875	100	0.563	Contact Map
1zu4A	1	0.5976	100	0.567	Contact Map
1rj9A	1	0.5332	100	0.571	Contact Map
1ls1A	1	0.5734	100	0.574	Contact Map
2px0A	4	0.5151	100	0.575	Contact Map
2v3cC	1	0.5775	100	0.583	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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