GREMLIN Database
CRFC - Clamp-binding protein CrfC
UniProt: P0DM85 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11210
Length: 742 (622)
Sequences: 1008 (895)
Seq/√Len: 35.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
242_E247_H6.4641.00
73_A259_A4.5601.00
79_K102_M4.1101.00
342_N403_I3.9451.00
300_D334_S3.6431.00
263_L295_L3.5651.00
95_L109_I3.4101.00
397_S400_A3.3091.00
194_A199_V3.2111.00
78_M102_M3.0881.00
315_L319_T3.0471.00
157_M160_L3.0251.00
226_E229_P2.8621.00
293_Y409_A2.8251.00
261_A264_A2.7961.00
179_P183_C2.7501.00
79_K242_E2.7221.00
175_L179_P2.7191.00
107_T256_L2.6911.00
118_P122_F2.6791.00
108_L221_H2.6381.00
599_Q603_D2.5481.00
264_A276_D2.5341.00
79_K270_Q2.5341.00
294_V328_Q2.5311.00
331_F405_A2.4601.00
78_M101_P2.4121.00
127_P218_E2.3761.00
78_M270_Q2.2840.99
102_M237_T2.2840.99
76_G101_P2.2630.99
237_T276_D2.2590.99
104_A247_H2.2570.99
297_N334_S2.2480.99
75_V256_L2.2470.99
79_K101_P2.2050.99
214_V247_H2.1900.99
79_K297_N2.1830.99
237_T241_N2.1780.99
247_H297_N2.1760.99
627_R630_E2.1650.99
414_A418_A2.1600.99
228_Y231_Q2.1460.99
101_P237_T2.1270.99
268_Y297_N2.1030.99
71_V233_T2.0660.99
99_N270_Q2.0600.99
78_M252_L2.0430.99
247_H270_Q2.0390.99
267_D298_K2.0340.99
450_Q454_N2.0330.99
78_M237_T2.0320.99
242_E270_Q2.0210.98
280_R294_V1.9630.98
261_A293_Y1.9570.98
102_M270_Q1.9540.98
106_P242_E1.9440.98
78_M249_Q1.9380.98
106_P244_G1.8950.98
85_T335_S1.8810.98
76_G240_P1.8790.98
78_M107_T1.8420.97
78_M214_V1.8410.97
268_Y302_Q1.8360.97
599_Q602_T1.8320.97
601_A604_E1.8290.97
163_R166_N1.8260.97
313_R317_S1.8220.97
97_N100_R1.7840.97
101_P104_A1.7830.97
111_H234_L1.7800.97
399_F402_P1.7770.97
79_K271_L1.7720.96
456_H459_E1.7700.96
162_Q165_E1.7660.96
96_P238_P1.7490.96
77_T241_N1.7440.96
95_L261_A1.7400.96
565_L568_S1.7280.96
79_K214_V1.7190.96
79_K247_H1.7040.96
264_A267_D1.6970.95
98_R102_M1.6960.95
296_V316_I1.6890.95
78_M271_L1.6850.95
267_D272_K1.6800.95
266_L297_N1.6790.95
242_E297_N1.6670.95
102_M214_V1.6670.95
84_T235_L1.6610.95
78_M240_P1.6520.95
106_P294_V1.6470.95
75_V107_T1.6440.95
128_I247_H1.6270.94
638_D645_A1.6240.94
79_K237_T1.6080.94
158_R161_M1.5830.93
242_E290_V1.5770.93
80_A95_L1.5770.93
70_M261_A1.5750.93
78_M242_E1.5650.93
77_T242_E1.5490.93
215_I247_H1.5380.92
696_A699_Q1.5370.92
101_P112_T1.5330.92
235_L255_Q1.5320.92
454_N468_N1.5290.92
704_V707_L1.5240.92
638_D642_L1.5220.92
688_Q691_L1.5170.92
256_L262_V1.5160.92
237_T291_P1.5160.92
584_P588_T1.5130.92
403_I406_L1.5010.91
277_E281_E1.4980.91
246_P298_K1.4960.91
77_T102_M1.4960.91
702_E706_R1.4920.91
244_G247_H1.4900.91
703_S708_M1.4890.91
241_N293_Y1.4780.91
276_D293_Y1.4750.91
639_Y643_Q1.4730.91
687_L694_S1.4730.91
77_T261_A1.4700.91
102_M297_N1.4590.90
47_S449_E1.4520.90
247_H259_A1.4470.90
242_E249_Q1.4450.90
613_R617_S1.4400.90
108_L219_F1.4390.90
236_D239_G1.4390.90
79_K98_R1.4360.90
73_A297_N1.4270.89
299_F309_A1.4150.89
104_A276_D1.4070.89
70_M293_Y1.4050.88
119_V221_H1.4030.88
711_Q714_Q1.3890.88
101_P315_L1.3890.88
703_S706_R1.3810.88
579_F582_V1.3800.88
38_D430_A1.3760.87
615_T618_R1.3660.87
338_G397_S1.3660.87
319_T323_G1.3600.87
486_S489_H1.3580.87
683_C686_E1.3560.87
70_M105_L1.3550.87
269_T298_K1.3520.86
214_V297_N1.3490.86
242_E259_A1.3460.86
297_N335_S1.3450.86
250_K254_Q1.3450.86
512_P515_E1.3430.86
295_L679_E1.3390.86
102_M247_H1.3370.86
316_I319_T1.3340.86
671_A675_T1.3280.85
325_I328_Q1.3270.85
157_M161_M1.3240.85
104_A267_D1.3230.85
78_M99_N1.3190.85
85_T265_V1.3180.85
102_M243_A1.3170.85
243_A252_L1.3150.85
259_A297_N1.3130.85
214_V264_A1.3080.85
264_A397_S1.3040.84
78_M215_I1.3040.84
101_P270_Q1.3030.84
454_N458_I1.2950.84
72_L91_G1.2950.84
29_K32_L1.2930.84
35_P42_L1.2930.84
71_V291_P1.2920.84
101_P271_L1.2900.84
99_N271_L1.2820.83
76_G324_C1.2810.83
596_I603_D1.2800.83
255_Q259_A1.2770.83
214_V242_E1.2770.83
102_M246_P1.2740.83
111_H228_Y1.2660.83
214_V270_Q1.2660.83
315_L323_G1.2600.82
82_K103_T1.2560.82
265_V422_A1.2560.82
78_M263_L1.2550.82
242_E264_A1.2530.82
75_V298_K1.2530.82
107_T259_A1.2520.82
174_Y177_A1.2490.82
96_P207_A1.2390.81
600_E604_E1.2340.81
271_L294_V1.2310.81
654_C658_A1.2300.81
80_A414_A1.2290.81
553_V557_I1.2280.81
100_R269_T1.2280.81
77_T291_P1.2280.81
108_L233_T1.2270.81
70_M102_M1.2240.80
637_V641_V1.2200.80
72_L273_S1.2180.80
120_L217_V1.2170.80
574_F577_P1.2170.80
264_A293_Y1.2160.80
102_M259_A1.2120.80
77_T247_H1.2060.79
123_S242_E1.2050.79
242_E268_Y1.2020.79
117_E223_A1.1990.79
264_A409_A1.1960.79
101_P241_N1.1950.79
80_A247_H1.1950.79
697_L700_Q1.1940.79
637_V642_L1.1930.79
75_V102_M1.1920.79
272_K298_K1.1910.78
73_A293_Y1.1880.78
293_Y329_Q1.1860.78
296_V332_P1.1850.78
171_E174_Y1.1840.78
266_L270_Q1.1820.78
84_T267_D1.1800.78
95_L103_T1.1790.78
123_S246_P1.1780.78
74_I101_P1.1770.78
244_G255_Q1.1680.77
111_H229_P1.1670.77
96_P102_M1.1660.77
293_Y405_A1.1640.77
263_L272_K1.1610.77
312_V320_L1.1600.77
107_T273_S1.1600.77
107_T232_L1.1570.76
100_R263_L1.1520.76
293_Y297_N1.1500.76
131_L135_L1.1480.76
70_M398_L1.1450.76
265_V331_F1.1410.75
493_Q497_A1.1410.75
102_M105_L1.1380.75
77_T414_A1.1360.75
214_V237_T1.1330.75
121_H221_H1.1300.75
174_Y186_S1.1300.75
78_M243_A1.1300.75
215_I242_E1.1290.75
85_T264_A1.1280.75
232_L410_A1.1270.75
653_Y656_Q1.1260.74
220_V337_W1.1250.74
101_P260_S1.1240.74
708_M711_Q1.1220.74
215_I264_A1.1210.74
85_T89_I1.1150.74
95_L237_T1.1120.74
88_A96_P1.1110.73
272_K279_V1.1110.73
86_I242_E1.1110.73
84_T263_L1.1050.73
176_G183_C1.1040.73
151_L200_D1.1010.73
108_L280_R1.0990.73
107_T271_L1.0990.73
331_F334_S1.0990.73
489_H495_Q1.0980.73
100_R298_K1.0970.72
217_V272_K1.0960.72
160_L166_N1.0950.72
28_E31_P1.0930.72
73_A253_N1.0920.72
596_I602_T1.0890.72
244_G268_Y1.0860.72
551_T559_Q1.0860.72
101_P272_K1.0850.72
76_G298_K1.0780.71
100_R272_K1.0780.71
337_W397_S1.0780.71
246_P297_N1.0770.71
101_P298_K1.0760.71
691_L703_S1.0740.71
240_P283_I1.0740.71
486_S490_F1.0720.71
136_Q139_L1.0720.71
598_R603_D1.0710.71
242_E397_S1.0700.71
706_R713_Q1.0680.70
241_N275_S1.0660.70
77_T231_Q1.0640.70
237_T270_Q1.0630.70
669_V672_G1.0630.70
194_A197_L1.0610.70
504_A507_Q1.0570.70
35_P41_Q1.0550.69
85_T101_P1.0540.69
160_L165_E1.0520.69
267_D312_V1.0510.69
160_L163_R1.0510.69
79_K246_P1.0490.69
697_L703_S1.0490.69
96_P297_N1.0430.69
341_A397_S1.0420.69
81_G236_D1.0410.68
101_P279_V1.0380.68
84_T271_L1.0350.68
58_L234_L1.0350.68
94_V101_P1.0320.68
579_F588_T1.0310.68
597_S604_E1.0300.68
72_L399_F1.0290.68
242_E272_K1.0290.68
165_E199_V1.0280.67
77_T272_K1.0240.67
599_Q604_E1.0240.67
402_P406_L1.0220.67
247_H271_L1.0210.67
251_M402_P1.0190.67
63_R555_R1.0170.67
58_L65_I1.0160.67
247_H264_A1.0130.66
179_P184_L1.0130.66
96_P241_N1.0120.66
97_N271_L1.0110.66
77_T273_S1.0100.66
640_S647_S1.0040.66
338_G403_I1.0040.66
105_L271_L1.0020.65
261_A296_V1.0010.65
650_V661_L1.0010.65
408_H412_A0.9960.65
35_P38_D0.9950.65
76_G81_G0.9910.65
78_M297_N0.9910.65
79_K293_Y0.9900.64
98_R244_G0.9890.64
313_R316_I0.9890.64
600_E603_D0.9820.64
77_T265_V0.9820.64
195_K198_D0.9770.63
242_E246_P0.9760.63
73_A220_V0.9750.63
240_P302_Q0.9750.63
99_N266_L0.9750.63
84_T266_L0.9740.63
78_M247_H0.9740.63
80_A261_A0.9730.63
77_T243_A0.9720.63
85_T275_S0.9690.63
225_L406_L0.9690.63
78_M261_A0.9660.63
485_T493_Q0.9650.62
661_L673_M0.9640.62
684_L691_L0.9610.62
101_P106_P0.9580.62
299_F397_S0.9570.62
101_P276_D0.9560.62
73_A242_E0.9520.61
430_A437_L0.9510.61
261_A272_K0.9510.61
692_R696_A0.9510.61
85_T308_D0.9500.61
241_N255_Q0.9500.61
100_R271_L0.9500.61
85_T402_P0.9490.61
319_T322_K0.9490.61
81_G103_T0.9480.61
263_L268_Y0.9470.61
227_S231_Q0.9450.61
31_P35_P0.9450.61
72_L211_H0.9450.61
316_I338_G0.9440.61
237_T264_A0.9420.61
74_I241_N0.9420.61
171_E182_H0.9400.60
95_L241_N0.9390.60
99_N276_D0.9390.60
103_T236_D0.9390.60
237_T338_G0.9370.60
237_T293_Y0.9360.60
287_G293_Y0.9320.60
215_I270_Q0.9300.60
527_A531_I0.9300.60
121_H219_F0.9290.59
697_L701_N0.9280.59
75_V79_K0.9270.59
476_I479_E0.9230.59
607_T616_F0.9210.59
102_M255_Q0.9210.59
700_Q703_S0.9200.59
101_P268_Y0.9190.59
102_M242_E0.9190.59
563_M571_R0.9180.59
123_S214_V0.9170.58
176_G180_I0.9150.58
242_E271_L0.9150.58
101_P249_Q0.9140.58
703_S717_M0.9110.58
698_R709_Q0.9110.58
260_S279_V0.9100.58
77_T246_P0.9090.58
77_T252_L0.9070.58
102_M244_G0.9070.58
84_T104_A0.9050.57
104_A241_N0.9030.57
244_G294_V0.9030.57
225_L228_Y0.9020.57
254_Q346_Y0.9010.57
77_T101_P0.9000.57
70_M77_T0.9000.57
78_M266_L0.8990.57
626_G631_K0.8990.57
489_H500_V0.8990.57
242_E302_Q0.8970.57
224_G229_P0.8970.57
69_E110_R0.8960.57
217_V397_S0.8960.57
102_M276_D0.8930.56
78_M406_L0.8920.56
490_F494_Q0.8910.56
560_Q684_L0.8880.56
313_R332_P0.8880.56
102_M272_K0.8870.56
101_P107_T0.8860.56
502_L507_Q0.8850.56
647_S650_V0.8850.56
470_A483_A0.8840.56
101_P296_V0.8840.56
37_D40_P0.8830.56
81_G239_G0.8820.56
698_R705_V0.8810.55
458_I461_S0.8790.55
295_L299_F0.8770.55
82_K236_D0.8760.55
263_L266_L0.8760.55
228_Y268_Y0.8750.55
339_Y403_I0.8750.55
175_L178_Q0.8740.55
241_N270_Q0.8740.55
263_L429_Y0.8730.55
453_Q457_Q0.8710.55
478_H648_A0.8710.55
102_M279_V0.8700.54
86_I97_N0.8700.54
247_H272_K0.8680.54
106_P255_Q0.8680.54
242_E328_Q0.8670.54
261_A297_N0.8640.54
121_H218_E0.8640.54
88_A335_S0.8590.54
106_P240_P0.8580.53
78_M260_S0.8560.53
266_L271_L0.8550.53
104_A271_L0.8540.53
101_P299_F0.8530.53
419_L422_A0.8520.53
482_L488_N0.8520.53
537_L543_E0.8520.53
224_G228_Y0.8500.53
77_T293_Y0.8480.53
596_I599_Q0.8470.52
456_H460_E0.8470.52
77_T260_S0.8460.52
296_V331_F0.8420.52
260_S315_L0.8390.52
82_K87_N0.8390.52
705_V717_M0.8380.52
260_S291_P0.8330.51
595_V604_E0.8320.51
79_K100_R0.8320.51
99_N102_M0.8300.51
610_G613_R0.8300.51
159_A162_Q0.8300.51
70_M290_V0.8280.51
267_D270_Q0.8270.51
611_V615_T0.8270.51
79_K259_A0.8270.51
574_F578_V0.8250.51
33_S36_G0.8250.51
78_M276_D0.8240.50
240_P252_L0.8240.50
324_C328_Q0.8240.50
79_K267_D0.8240.50
451_L462_L0.8230.50
89_I414_A0.8230.50
63_R66_S0.8220.50
36_G43_A0.8190.50
80_A676_F0.8170.50
78_M105_L0.8160.50
234_L617_S0.8160.50
215_I296_V0.8140.50
100_R270_Q0.8140.50
274_I278_E0.8140.50
500_V503_A0.8140.50
75_V241_N0.8130.50
78_M267_D0.8120.49
486_S502_L0.8100.49
59_N667_E0.8050.49
111_H240_P0.8040.49
73_A247_H0.8040.49
597_S600_E0.8020.49
650_V655_Q0.8010.48
214_V241_N0.8000.48
88_A270_Q0.7970.48
532_S536_T0.7970.48
601_A605_Q0.7970.48
166_N456_H0.7940.48
458_I462_L0.7940.48
40_P43_A0.7930.48
497_A500_V0.7930.48
80_A267_D0.7900.48
235_L267_D0.7870.47
514_S518_T0.7870.47
246_P255_Q0.7860.47
214_V266_L0.7860.47
554_I557_I0.7860.47
215_I273_S0.7860.47
79_K123_S0.7850.47
74_I263_L0.7840.47
422_A429_Y0.7830.47
103_T239_G0.7830.47
104_A257_A0.7830.47
334_S337_W0.7820.47
463_Q466_Q0.7820.47
197_L283_I0.7810.47
267_D297_N0.7800.47
108_L296_V0.7790.47
112_T224_G0.7780.46
111_H268_Y0.7780.46
268_Y299_F0.7760.46
78_M241_N0.7750.46
689_T702_E0.7750.46
58_L581_G0.7730.46
428_N432_Q0.7720.46
579_F653_Y0.7720.46
106_P280_R0.7720.46
247_H296_V0.7720.46
268_Y276_D0.7710.46
639_Y645_A0.7700.46
703_S716_V0.7700.46
101_P214_V0.7690.46
485_T502_L0.7680.46
100_R246_P0.7670.46
331_F398_L0.7650.45
78_M123_S0.7620.45
696_A703_S0.7610.45
72_L80_A0.7590.45
259_A263_L0.7580.45
71_V260_S0.7580.45
86_I308_D0.7580.45
98_R268_Y0.7570.45
99_N269_T0.7570.45
94_V222_L0.7560.45
255_Q293_Y0.7560.45
593_S597_S0.7540.44
98_R237_T0.7540.44
95_L104_A0.7500.44
266_L302_Q0.7500.44
700_Q706_R0.7490.44
252_L273_S0.7480.44
214_V246_P0.7480.44
95_L102_M0.7470.44
78_M294_V0.7460.44
76_G82_K0.7430.43
101_P287_G0.7410.43
70_M235_L0.7400.43
495_Q500_V0.7390.43
102_M267_D0.7390.43
79_K302_Q0.7370.43
80_A268_Y0.7370.43
128_I216_E0.7370.43
215_I228_Y0.7370.43
297_N339_Y0.7350.43
476_I480_I0.7350.43
695_L699_Q0.7320.43
235_L244_G0.7310.42
686_E690_R0.7310.42
241_N261_A0.7310.42
74_I79_K0.7310.42
426_L646_L0.7290.42
409_A413_N0.7290.42
430_A502_L0.7290.42
237_T240_P0.7270.42
270_Q301_Q0.7260.42
697_L708_M0.7240.42
78_M244_G0.7240.42
105_L267_D0.7240.42
85_T107_T0.7230.42
249_Q252_L0.7210.42
97_N243_A0.7200.42
297_N341_A0.7200.42
74_I100_R0.7200.42
297_N300_D0.7200.42
96_P335_S0.7190.41
77_T214_V0.7180.41
79_K99_N0.7160.41
75_V272_K0.7160.41
119_V223_A0.7160.41
94_V112_T0.7150.41
709_Q714_Q0.7140.41
82_K239_G0.7130.41
653_Y661_L0.7130.41
86_I257_A0.7130.41
237_T268_Y0.7120.41
700_Q710_Q0.7110.41
71_V293_Y0.7090.41
73_A302_Q0.7090.41
100_R203_F0.7090.41
701_N708_M0.7090.41
98_R270_Q0.7070.40
174_Y178_Q0.7070.40
75_V266_L0.7060.40
102_M215_I0.7050.40
77_T257_A0.7040.40
705_V708_M0.7030.40
467_L566_S0.7010.40
228_Y240_P0.7000.40
705_V712_L0.7000.40
78_M269_T0.6990.40
393_L397_S0.6980.40
217_V242_E0.6950.39
451_L455_I0.6940.39
141_D295_L0.6940.39
73_A243_A0.6930.39
77_T251_M0.6930.39
243_A273_S0.6930.39
85_T302_Q0.6920.39
122_F217_V0.6910.39
296_V302_Q0.6890.39
253_N297_N0.6890.39
101_P242_E0.6880.39
78_M413_N0.6880.39
598_R604_E0.6870.39
70_M118_P0.6870.39
77_T240_P0.6870.39
84_T99_N0.6850.39
68_L237_T0.6850.39
240_P296_V0.6840.39
291_P409_A0.6840.39
613_R622_Q0.6840.39
77_T86_I0.6840.39
78_M262_V0.6840.39
195_K199_V0.6840.39
249_Q266_L0.6830.38
152_E156_D0.6820.38
713_Q717_M0.6810.38
176_G179_P0.6800.38
700_Q705_V0.6790.38
311_Q314_A0.6790.38
341_A394_W0.6770.38
91_G101_P0.6750.38
505_L508_D0.6730.38
272_K291_P0.6720.38
282_A286_V0.6720.38
123_S269_T0.6720.38
232_L263_L0.6700.37
28_E32_L0.6700.37
490_F507_Q0.6690.37
457_Q531_I0.6660.37
299_F332_P0.6640.37
266_L269_T0.6640.37
177_A181_F0.6620.37
73_A235_L0.6610.37
314_A317_S0.6600.37
240_P406_L0.6600.37
604_E607_T0.6600.37
123_S128_I0.6590.36
77_T297_N0.6590.36
434_R438_D0.6570.36
109_I240_P0.6560.36
710_Q713_Q0.6560.36
678_A681_A0.6550.36
578_V583_V0.6550.36
524_L620_L0.6540.36
268_Y414_A0.6540.36
237_T267_D0.6520.36
247_H290_V0.6510.36
102_M312_V0.6490.36
261_A294_V0.6480.36
214_V271_L0.6480.36
265_V296_V0.6460.35
251_M271_L0.6460.35
247_H298_K0.6460.35
244_G297_N0.6450.35
502_L596_I0.6450.35
703_S713_Q0.6450.35
247_H328_Q0.6440.35
231_Q252_L0.6440.35
106_P259_A0.6430.35
120_L124_H0.6430.35
123_S237_T0.6430.35
104_A325_I0.6430.35
489_H496_D0.6430.35
107_T422_A0.6420.35
664_Q705_V0.6420.35
317_S563_M0.6420.35
69_E429_Y0.6400.35
75_V279_V0.6400.35
79_K241_N0.6400.35
80_A269_T0.6390.35
490_F496_D0.6390.35
293_Y302_Q0.6380.35
576_F582_V0.6380.35
104_A270_Q0.6380.35
336_M340_L0.6380.35
403_I407_L0.6370.35
626_G630_E0.6370.35
237_T252_L0.6370.35
184_L188_N0.6370.35
638_D641_V0.6360.35
287_G409_A0.6350.35
253_N282_A0.6350.35
317_S321_M0.6340.35
692_R702_E0.6330.34
685_T688_Q0.6320.34
404_Q589_R0.6310.34
241_N271_L0.6300.34
173_Y176_G0.6290.34
489_H492_R0.6280.34
123_S276_D0.6260.34
298_K329_Q0.6260.34
91_G109_I0.6250.34
338_G341_A0.6240.34
582_V588_T0.6230.34
79_K243_A0.6230.34
254_Q258_R0.6210.33
342_N394_W0.6210.33
176_G184_L0.6200.33
452_R561_V0.6190.33
94_V659_K0.6190.33
37_D41_Q0.6180.33
72_L433_A0.6170.33
266_L294_V0.6170.33
80_A276_D0.6170.33
56_A90_V0.6160.33
431_Q481_E0.6160.33
98_R231_Q0.6150.33
59_N464_L0.6150.33
260_S269_T0.6150.33
698_R711_Q0.6130.33
73_A255_Q0.6130.33
77_T290_V0.6130.33
448_C452_R0.6120.33
71_V259_A0.6110.33
81_G87_N0.6100.33
118_P217_V0.6100.33
77_T275_S0.6090.33
334_S338_G0.6080.32
84_T215_I0.6070.32
241_N264_A0.6060.32
641_V645_A0.6060.32
180_I185_K0.6050.32
218_E222_L0.6050.32
84_T297_N0.6040.32
478_H644_R0.6040.32
510_S515_E0.6040.32
77_T269_T0.6030.32
597_S601_A0.6020.32
77_T80_A0.6020.32
79_K109_I0.6010.32
118_P341_A0.6000.32
270_Q298_K0.6000.32
597_S603_D0.5990.32
42_L640_S0.5990.32
251_M260_S0.5980.32
247_H266_L0.5980.32
252_L260_S0.5980.32
155_K160_L0.5980.32
595_V600_E0.5970.32
215_I251_M0.5960.32
157_M166_N0.5960.32
648_A656_Q0.5960.32
103_T107_T0.5950.32
600_E605_Q0.5950.32
76_G89_I0.5920.31
78_M272_K0.5900.31
399_F403_I0.5890.31
582_V587_N0.5890.31
284_L287_G0.5880.31
76_G244_G0.5870.31
86_I210_E0.5860.31
36_G573_G0.5860.31
96_P227_S0.5850.31
71_V297_N0.5850.31
333_V395_E0.5810.30
493_Q499_K0.5800.30
594_E604_E0.5790.30
593_S604_E0.5780.30
214_V397_S0.5780.30
313_R330_I0.5770.30
683_C687_L0.5770.30
237_T302_Q0.5760.30
77_T268_Y0.5760.30
102_M123_S0.5760.30
128_I242_E0.5760.30
263_L297_N0.5760.30
101_P244_G0.5760.30
98_R246_P0.5760.30
106_P217_V0.5750.30
211_H488_N0.5740.30
86_I123_S0.5740.30
508_D511_E0.5710.30
490_F506_F0.5700.30
59_N684_L0.5700.30
264_A270_Q0.5690.30
706_R709_Q0.5690.30
80_A251_M0.5680.30
442_H468_N0.5660.29
705_V710_Q0.5660.29
106_P247_H0.5650.29
34_V37_D0.5650.29
707_L714_Q0.5650.29
694_S698_R0.5640.29
267_D271_L0.5640.29
75_V84_T0.5620.29
123_S264_A0.5620.29
262_V680_F0.5620.29
318_G399_F0.5620.29
709_Q713_Q0.5610.29
477_K481_E0.5600.29
105_L296_V0.5600.29
297_N409_A0.5600.29
78_M112_T0.5600.29
249_Q291_P0.5590.29
283_I699_Q0.5580.29
231_Q414_A0.5580.29
479_E483_A0.5580.29
76_G236_D0.5570.29
526_T530_T0.5560.29
77_T298_K0.5550.29
640_S644_R0.5550.29
702_E708_M0.5550.29
180_I187_L0.5540.29
100_R266_L0.5540.29
43_A163_R0.5530.28
78_M84_T0.5520.28
98_R296_V0.5520.28
242_E255_Q0.5510.28
152_E155_K0.5500.28
70_M252_L0.5500.28
108_L240_P0.5490.28
106_P233_T0.5490.28
71_V106_P0.5490.28
553_V556_P0.5480.28
594_E601_A0.5480.28
184_L187_L0.5480.28
315_L320_L0.5470.28
493_Q504_A0.5470.28
111_H410_A0.5460.28
328_Q332_P0.5460.28
249_Q267_D0.5450.28
81_G238_P0.5430.28
492_R497_A0.5420.28
280_R406_L0.5410.28
109_I237_T0.5410.28
240_P251_M0.5400.28
109_I406_L0.5390.27
77_T302_Q0.5390.27
714_Q717_M0.5390.27
620_L627_R0.5390.27
32_L465_L0.5370.27
687_L702_E0.5370.27
78_M228_Y0.5370.27
70_M98_R0.5370.27
240_P273_S0.5360.27
108_L242_E0.5350.27
464_L470_A0.5350.27
398_L401_Q0.5340.27
338_G398_L0.5330.27
298_K308_D0.5310.27
96_P266_L0.5300.27
598_R601_A0.5300.27
78_M118_P0.5300.27
492_R502_L0.5300.27
693_E696_A0.5280.27
231_Q406_L0.5280.27
103_T228_Y0.5270.27
704_V708_M0.5270.27
249_Q253_N0.5270.27
457_Q460_E0.5270.27
563_M566_S0.5270.27
423_A483_A0.5270.27
59_N63_R0.5260.27
90_V418_A0.5260.27
101_P247_H0.5240.26
271_L299_F0.5240.26
34_V38_D0.5230.26
76_G112_T0.5230.26
100_R252_L0.5230.26
494_Q502_L0.5220.26
79_K268_Y0.5210.26
86_I287_G0.5200.26
71_V107_T0.5180.26
256_L511_E0.5180.26
123_S208_A0.5180.26
223_A271_L0.5180.26
311_Q315_L0.5170.26
232_L402_P0.5160.26
707_L711_Q0.5150.26
100_R247_H0.5150.26
104_A297_N0.5150.26
579_F586_F0.5150.26
297_N338_G0.5150.26
271_L297_N0.5140.26
243_A276_D0.5130.26
85_T232_L0.5130.26
214_V255_Q0.5120.26
250_K264_A0.5110.26
108_L255_Q0.5110.26
664_Q673_M0.5110.26
54_R252_L0.5100.26
267_D339_Y0.5100.26
111_H231_Q0.5100.26
158_R164_I0.5090.25
433_A482_L0.5090.25
231_Q235_L0.5090.25
437_L712_L0.5080.25
232_L293_Y0.5060.25
79_K91_G0.5040.25
108_L244_G0.5040.25
104_A237_T0.5040.25
637_V645_A0.5040.25
72_L637_V0.5030.25
422_A425_K0.5030.25
256_L259_A0.5030.25
111_H118_P0.5020.25
235_L242_E0.5010.25
247_H253_N0.5010.25
101_P283_I0.5010.25
554_I558_E0.5000.25
85_T279_V0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2j69A 1 0.8208 100 0.633 Contact Map
4aurA 1 0.717 100 0.736 Contact Map
4uudA 5 0.6617 100 0.77 Contact Map
4bejA 2 0.7197 100 0.77 Contact Map
3w6pA 2 0.438 99.9 0.785 Contact Map
2akaB 1 0.3881 99.9 0.793 Contact Map
2x2eA 2 0.4353 99.9 0.798 Contact Map
3t34A 2 0.4461 99.9 0.801 Contact Map
3zvrA 1 0.6105 99.9 0.816 Contact Map
1jwyB 1 0.372 99.8 0.824 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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