CRFC - ECOLI - GREMLIN Contacts

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CRFC - Clamp-binding protein CrfC

UniProt:	P0DM85	Sequences: MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLALPWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPMTALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRALMQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVEFVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISDEEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVSSMWGYLANRARYELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQLWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQLRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALKVQLAALFQDDSEPLSEIRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELSESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVRETFSRWLNQPDWGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFASCLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAERY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11210
Length:	742 (622)
Sequences:	1008 (895)
Seq/√Len:	35.9

ECOLI - CRFC
BACSU - YPBR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
242_E	247_H	6.464	1.00
73_A	259_A	4.560	1.00
79_K	102_M	4.110	1.00
342_N	403_I	3.945	1.00
300_D	334_S	3.643	1.00
263_L	295_L	3.565	1.00
95_L	109_I	3.410	1.00
397_S	400_A	3.309	1.00
194_A	199_V	3.211	1.00
78_M	102_M	3.088	1.00
315_L	319_T	3.047	1.00
157_M	160_L	3.025	1.00
226_E	229_P	2.862	1.00
293_Y	409_A	2.825	1.00
261_A	264_A	2.796	1.00
179_P	183_C	2.750	1.00
79_K	242_E	2.722	1.00
175_L	179_P	2.719	1.00
107_T	256_L	2.691	1.00
118_P	122_F	2.679	1.00
108_L	221_H	2.638	1.00
599_Q	603_D	2.548	1.00
264_A	276_D	2.534	1.00
79_K	270_Q	2.534	1.00
294_V	328_Q	2.531	1.00
331_F	405_A	2.460	1.00
78_M	101_P	2.412	1.00
127_P	218_E	2.376	1.00
78_M	270_Q	2.284	0.99
102_M	237_T	2.284	0.99
76_G	101_P	2.263	0.99
237_T	276_D	2.259	0.99
104_A	247_H	2.257	0.99
297_N	334_S	2.248	0.99
75_V	256_L	2.247	0.99
79_K	101_P	2.205	0.99
214_V	247_H	2.190	0.99
79_K	297_N	2.183	0.99
237_T	241_N	2.178	0.99
247_H	297_N	2.176	0.99
627_R	630_E	2.165	0.99
414_A	418_A	2.160	0.99
228_Y	231_Q	2.146	0.99
101_P	237_T	2.127	0.99
268_Y	297_N	2.103	0.99
71_V	233_T	2.066	0.99
99_N	270_Q	2.060	0.99
78_M	252_L	2.043	0.99
247_H	270_Q	2.039	0.99
267_D	298_K	2.034	0.99
450_Q	454_N	2.033	0.99
78_M	237_T	2.032	0.99
242_E	270_Q	2.021	0.98
280_R	294_V	1.963	0.98
261_A	293_Y	1.957	0.98
102_M	270_Q	1.954	0.98
106_P	242_E	1.944	0.98
78_M	249_Q	1.938	0.98
106_P	244_G	1.895	0.98
85_T	335_S	1.881	0.98
76_G	240_P	1.879	0.98
78_M	107_T	1.842	0.97
78_M	214_V	1.841	0.97
268_Y	302_Q	1.836	0.97
599_Q	602_T	1.832	0.97
601_A	604_E	1.829	0.97
163_R	166_N	1.826	0.97
313_R	317_S	1.822	0.97
97_N	100_R	1.784	0.97
101_P	104_A	1.783	0.97
111_H	234_L	1.780	0.97
399_F	402_P	1.777	0.97
79_K	271_L	1.772	0.96
456_H	459_E	1.770	0.96
162_Q	165_E	1.766	0.96
96_P	238_P	1.749	0.96
77_T	241_N	1.744	0.96
95_L	261_A	1.740	0.96
565_L	568_S	1.728	0.96
79_K	214_V	1.719	0.96
79_K	247_H	1.704	0.96
264_A	267_D	1.697	0.95
98_R	102_M	1.696	0.95
296_V	316_I	1.689	0.95
78_M	271_L	1.685	0.95
267_D	272_K	1.680	0.95
266_L	297_N	1.679	0.95
242_E	297_N	1.667	0.95
102_M	214_V	1.667	0.95
84_T	235_L	1.661	0.95
78_M	240_P	1.652	0.95
106_P	294_V	1.647	0.95
75_V	107_T	1.644	0.95
128_I	247_H	1.627	0.94
638_D	645_A	1.624	0.94
79_K	237_T	1.608	0.94
158_R	161_M	1.583	0.93
242_E	290_V	1.577	0.93
80_A	95_L	1.577	0.93
70_M	261_A	1.575	0.93
78_M	242_E	1.565	0.93
77_T	242_E	1.549	0.93
215_I	247_H	1.538	0.92
696_A	699_Q	1.537	0.92
101_P	112_T	1.533	0.92
235_L	255_Q	1.532	0.92
454_N	468_N	1.529	0.92
704_V	707_L	1.524	0.92
638_D	642_L	1.522	0.92
688_Q	691_L	1.517	0.92
256_L	262_V	1.516	0.92
237_T	291_P	1.516	0.92
584_P	588_T	1.513	0.92
403_I	406_L	1.501	0.91
277_E	281_E	1.498	0.91
246_P	298_K	1.496	0.91
77_T	102_M	1.496	0.91
702_E	706_R	1.492	0.91
244_G	247_H	1.490	0.91
703_S	708_M	1.489	0.91
241_N	293_Y	1.478	0.91
276_D	293_Y	1.475	0.91
639_Y	643_Q	1.473	0.91
687_L	694_S	1.473	0.91
77_T	261_A	1.470	0.91
102_M	297_N	1.459	0.90
47_S	449_E	1.452	0.90
247_H	259_A	1.447	0.90
242_E	249_Q	1.445	0.90
613_R	617_S	1.440	0.90
108_L	219_F	1.439	0.90
236_D	239_G	1.439	0.90
79_K	98_R	1.436	0.90
73_A	297_N	1.427	0.89
299_F	309_A	1.415	0.89
104_A	276_D	1.407	0.89
70_M	293_Y	1.405	0.88
119_V	221_H	1.403	0.88
711_Q	714_Q	1.389	0.88
101_P	315_L	1.389	0.88
703_S	706_R	1.381	0.88
579_F	582_V	1.380	0.88
38_D	430_A	1.376	0.87
615_T	618_R	1.366	0.87
338_G	397_S	1.366	0.87
319_T	323_G	1.360	0.87
486_S	489_H	1.358	0.87
683_C	686_E	1.356	0.87
70_M	105_L	1.355	0.87
269_T	298_K	1.352	0.86
214_V	297_N	1.349	0.86
242_E	259_A	1.346	0.86
297_N	335_S	1.345	0.86
250_K	254_Q	1.345	0.86
512_P	515_E	1.343	0.86
295_L	679_E	1.339	0.86
102_M	247_H	1.337	0.86
316_I	319_T	1.334	0.86
671_A	675_T	1.328	0.85
325_I	328_Q	1.327	0.85
157_M	161_M	1.324	0.85
104_A	267_D	1.323	0.85
78_M	99_N	1.319	0.85
85_T	265_V	1.318	0.85
102_M	243_A	1.317	0.85
243_A	252_L	1.315	0.85
259_A	297_N	1.313	0.85
214_V	264_A	1.308	0.85
264_A	397_S	1.304	0.84
78_M	215_I	1.304	0.84
101_P	270_Q	1.303	0.84
454_N	458_I	1.295	0.84
72_L	91_G	1.295	0.84
29_K	32_L	1.293	0.84
35_P	42_L	1.293	0.84
71_V	291_P	1.292	0.84
101_P	271_L	1.290	0.84
99_N	271_L	1.282	0.83
76_G	324_C	1.281	0.83
596_I	603_D	1.280	0.83
255_Q	259_A	1.277	0.83
214_V	242_E	1.277	0.83
102_M	246_P	1.274	0.83
111_H	228_Y	1.266	0.83
214_V	270_Q	1.266	0.83
315_L	323_G	1.260	0.82
82_K	103_T	1.256	0.82
265_V	422_A	1.256	0.82
78_M	263_L	1.255	0.82
242_E	264_A	1.253	0.82
75_V	298_K	1.253	0.82
107_T	259_A	1.252	0.82
174_Y	177_A	1.249	0.82
96_P	207_A	1.239	0.81
600_E	604_E	1.234	0.81
271_L	294_V	1.231	0.81
654_C	658_A	1.230	0.81
80_A	414_A	1.229	0.81
553_V	557_I	1.228	0.81
100_R	269_T	1.228	0.81
77_T	291_P	1.228	0.81
108_L	233_T	1.227	0.81
70_M	102_M	1.224	0.80
637_V	641_V	1.220	0.80
72_L	273_S	1.218	0.80
120_L	217_V	1.217	0.80
574_F	577_P	1.217	0.80
264_A	293_Y	1.216	0.80
102_M	259_A	1.212	0.80
77_T	247_H	1.206	0.79
123_S	242_E	1.205	0.79
242_E	268_Y	1.202	0.79
117_E	223_A	1.199	0.79
264_A	409_A	1.196	0.79
101_P	241_N	1.195	0.79
80_A	247_H	1.195	0.79
697_L	700_Q	1.194	0.79
637_V	642_L	1.193	0.79
75_V	102_M	1.192	0.79
272_K	298_K	1.191	0.78
73_A	293_Y	1.188	0.78
293_Y	329_Q	1.186	0.78
296_V	332_P	1.185	0.78
171_E	174_Y	1.184	0.78
266_L	270_Q	1.182	0.78
84_T	267_D	1.180	0.78
95_L	103_T	1.179	0.78
123_S	246_P	1.178	0.78
74_I	101_P	1.177	0.78
244_G	255_Q	1.168	0.77
111_H	229_P	1.167	0.77
96_P	102_M	1.166	0.77
293_Y	405_A	1.164	0.77
263_L	272_K	1.161	0.77
312_V	320_L	1.160	0.77
107_T	273_S	1.160	0.77
107_T	232_L	1.157	0.76
100_R	263_L	1.152	0.76
293_Y	297_N	1.150	0.76
131_L	135_L	1.148	0.76
70_M	398_L	1.145	0.76
265_V	331_F	1.141	0.75
493_Q	497_A	1.141	0.75
102_M	105_L	1.138	0.75
77_T	414_A	1.136	0.75
214_V	237_T	1.133	0.75
121_H	221_H	1.130	0.75
174_Y	186_S	1.130	0.75
78_M	243_A	1.130	0.75
215_I	242_E	1.129	0.75
85_T	264_A	1.128	0.75
232_L	410_A	1.127	0.75
653_Y	656_Q	1.126	0.74
220_V	337_W	1.125	0.74
101_P	260_S	1.124	0.74
708_M	711_Q	1.122	0.74
215_I	264_A	1.121	0.74
85_T	89_I	1.115	0.74
95_L	237_T	1.112	0.74
88_A	96_P	1.111	0.73
272_K	279_V	1.111	0.73
86_I	242_E	1.111	0.73
84_T	263_L	1.105	0.73
176_G	183_C	1.104	0.73
151_L	200_D	1.101	0.73
108_L	280_R	1.099	0.73
107_T	271_L	1.099	0.73
331_F	334_S	1.099	0.73
489_H	495_Q	1.098	0.73
100_R	298_K	1.097	0.72
217_V	272_K	1.096	0.72
160_L	166_N	1.095	0.72
28_E	31_P	1.093	0.72
73_A	253_N	1.092	0.72
596_I	602_T	1.089	0.72
244_G	268_Y	1.086	0.72
551_T	559_Q	1.086	0.72
101_P	272_K	1.085	0.72
76_G	298_K	1.078	0.71
100_R	272_K	1.078	0.71
337_W	397_S	1.078	0.71
246_P	297_N	1.077	0.71
101_P	298_K	1.076	0.71
691_L	703_S	1.074	0.71
240_P	283_I	1.074	0.71
486_S	490_F	1.072	0.71
136_Q	139_L	1.072	0.71
598_R	603_D	1.071	0.71
242_E	397_S	1.070	0.71
706_R	713_Q	1.068	0.70
241_N	275_S	1.066	0.70
77_T	231_Q	1.064	0.70
237_T	270_Q	1.063	0.70
669_V	672_G	1.063	0.70
194_A	197_L	1.061	0.70
504_A	507_Q	1.057	0.70
35_P	41_Q	1.055	0.69
85_T	101_P	1.054	0.69
160_L	165_E	1.052	0.69
267_D	312_V	1.051	0.69
160_L	163_R	1.051	0.69
79_K	246_P	1.049	0.69
697_L	703_S	1.049	0.69
96_P	297_N	1.043	0.69
341_A	397_S	1.042	0.69
81_G	236_D	1.041	0.68
101_P	279_V	1.038	0.68
84_T	271_L	1.035	0.68
58_L	234_L	1.035	0.68
94_V	101_P	1.032	0.68
579_F	588_T	1.031	0.68
597_S	604_E	1.030	0.68
72_L	399_F	1.029	0.68
242_E	272_K	1.029	0.68
165_E	199_V	1.028	0.67
77_T	272_K	1.024	0.67
599_Q	604_E	1.024	0.67
402_P	406_L	1.022	0.67
247_H	271_L	1.021	0.67
251_M	402_P	1.019	0.67
63_R	555_R	1.017	0.67
58_L	65_I	1.016	0.67
247_H	264_A	1.013	0.66
179_P	184_L	1.013	0.66
96_P	241_N	1.012	0.66
97_N	271_L	1.011	0.66
77_T	273_S	1.010	0.66
640_S	647_S	1.004	0.66
338_G	403_I	1.004	0.66
105_L	271_L	1.002	0.65
261_A	296_V	1.001	0.65
650_V	661_L	1.001	0.65
408_H	412_A	0.996	0.65
35_P	38_D	0.995	0.65
76_G	81_G	0.991	0.65
78_M	297_N	0.991	0.65
79_K	293_Y	0.990	0.64
98_R	244_G	0.989	0.64
313_R	316_I	0.989	0.64
600_E	603_D	0.982	0.64
77_T	265_V	0.982	0.64
195_K	198_D	0.977	0.63
242_E	246_P	0.976	0.63
73_A	220_V	0.975	0.63
240_P	302_Q	0.975	0.63
99_N	266_L	0.975	0.63
84_T	266_L	0.974	0.63
78_M	247_H	0.974	0.63
80_A	261_A	0.973	0.63
77_T	243_A	0.972	0.63
85_T	275_S	0.969	0.63
225_L	406_L	0.969	0.63
78_M	261_A	0.966	0.63
485_T	493_Q	0.965	0.62
661_L	673_M	0.964	0.62
684_L	691_L	0.961	0.62
101_P	106_P	0.958	0.62
299_F	397_S	0.957	0.62
101_P	276_D	0.956	0.62
73_A	242_E	0.952	0.61
430_A	437_L	0.951	0.61
261_A	272_K	0.951	0.61
692_R	696_A	0.951	0.61
85_T	308_D	0.950	0.61
241_N	255_Q	0.950	0.61
100_R	271_L	0.950	0.61
85_T	402_P	0.949	0.61
319_T	322_K	0.949	0.61
81_G	103_T	0.948	0.61
263_L	268_Y	0.947	0.61
227_S	231_Q	0.945	0.61
31_P	35_P	0.945	0.61
72_L	211_H	0.945	0.61
316_I	338_G	0.944	0.61
237_T	264_A	0.942	0.61
74_I	241_N	0.942	0.61
171_E	182_H	0.940	0.60
95_L	241_N	0.939	0.60
99_N	276_D	0.939	0.60
103_T	236_D	0.939	0.60
237_T	338_G	0.937	0.60
237_T	293_Y	0.936	0.60
287_G	293_Y	0.932	0.60
215_I	270_Q	0.930	0.60
527_A	531_I	0.930	0.60
121_H	219_F	0.929	0.59
697_L	701_N	0.928	0.59
75_V	79_K	0.927	0.59
476_I	479_E	0.923	0.59
607_T	616_F	0.921	0.59
102_M	255_Q	0.921	0.59
700_Q	703_S	0.920	0.59
101_P	268_Y	0.919	0.59
102_M	242_E	0.919	0.59
563_M	571_R	0.918	0.59
123_S	214_V	0.917	0.58
176_G	180_I	0.915	0.58
242_E	271_L	0.915	0.58
101_P	249_Q	0.914	0.58
703_S	717_M	0.911	0.58
698_R	709_Q	0.911	0.58
260_S	279_V	0.910	0.58
77_T	246_P	0.909	0.58
77_T	252_L	0.907	0.58
102_M	244_G	0.907	0.58
84_T	104_A	0.905	0.57
104_A	241_N	0.903	0.57
244_G	294_V	0.903	0.57
225_L	228_Y	0.902	0.57
254_Q	346_Y	0.901	0.57
77_T	101_P	0.900	0.57
70_M	77_T	0.900	0.57
78_M	266_L	0.899	0.57
626_G	631_K	0.899	0.57
489_H	500_V	0.899	0.57
242_E	302_Q	0.897	0.57
224_G	229_P	0.897	0.57
69_E	110_R	0.896	0.57
217_V	397_S	0.896	0.57
102_M	276_D	0.893	0.56
78_M	406_L	0.892	0.56
490_F	494_Q	0.891	0.56
560_Q	684_L	0.888	0.56
313_R	332_P	0.888	0.56
102_M	272_K	0.887	0.56
101_P	107_T	0.886	0.56
502_L	507_Q	0.885	0.56
647_S	650_V	0.885	0.56
470_A	483_A	0.884	0.56
101_P	296_V	0.884	0.56
37_D	40_P	0.883	0.56
81_G	239_G	0.882	0.56
698_R	705_V	0.881	0.55
458_I	461_S	0.879	0.55
295_L	299_F	0.877	0.55
82_K	236_D	0.876	0.55
263_L	266_L	0.876	0.55
228_Y	268_Y	0.875	0.55
339_Y	403_I	0.875	0.55
175_L	178_Q	0.874	0.55
241_N	270_Q	0.874	0.55
263_L	429_Y	0.873	0.55
453_Q	457_Q	0.871	0.55
478_H	648_A	0.871	0.55
102_M	279_V	0.870	0.54
86_I	97_N	0.870	0.54
247_H	272_K	0.868	0.54
106_P	255_Q	0.868	0.54
242_E	328_Q	0.867	0.54
261_A	297_N	0.864	0.54
121_H	218_E	0.864	0.54
88_A	335_S	0.859	0.54
106_P	240_P	0.858	0.53
78_M	260_S	0.856	0.53
266_L	271_L	0.855	0.53
104_A	271_L	0.854	0.53
101_P	299_F	0.853	0.53
419_L	422_A	0.852	0.53
482_L	488_N	0.852	0.53
537_L	543_E	0.852	0.53
224_G	228_Y	0.850	0.53
77_T	293_Y	0.848	0.53
596_I	599_Q	0.847	0.52
456_H	460_E	0.847	0.52
77_T	260_S	0.846	0.52
296_V	331_F	0.842	0.52
260_S	315_L	0.839	0.52
82_K	87_N	0.839	0.52
705_V	717_M	0.838	0.52
260_S	291_P	0.833	0.51
595_V	604_E	0.832	0.51
79_K	100_R	0.832	0.51
99_N	102_M	0.830	0.51
610_G	613_R	0.830	0.51
159_A	162_Q	0.830	0.51
70_M	290_V	0.828	0.51
267_D	270_Q	0.827	0.51
611_V	615_T	0.827	0.51
79_K	259_A	0.827	0.51
574_F	578_V	0.825	0.51
33_S	36_G	0.825	0.51
78_M	276_D	0.824	0.50
240_P	252_L	0.824	0.50
324_C	328_Q	0.824	0.50
79_K	267_D	0.824	0.50
451_L	462_L	0.823	0.50
89_I	414_A	0.823	0.50
63_R	66_S	0.822	0.50
36_G	43_A	0.819	0.50
80_A	676_F	0.817	0.50
78_M	105_L	0.816	0.50
234_L	617_S	0.816	0.50
215_I	296_V	0.814	0.50
100_R	270_Q	0.814	0.50
274_I	278_E	0.814	0.50
500_V	503_A	0.814	0.50
75_V	241_N	0.813	0.50
78_M	267_D	0.812	0.49
486_S	502_L	0.810	0.49
59_N	667_E	0.805	0.49
111_H	240_P	0.804	0.49
73_A	247_H	0.804	0.49
597_S	600_E	0.802	0.49
650_V	655_Q	0.801	0.48
214_V	241_N	0.800	0.48
88_A	270_Q	0.797	0.48
532_S	536_T	0.797	0.48
601_A	605_Q	0.797	0.48
166_N	456_H	0.794	0.48
458_I	462_L	0.794	0.48
40_P	43_A	0.793	0.48
497_A	500_V	0.793	0.48
80_A	267_D	0.790	0.48
235_L	267_D	0.787	0.47
514_S	518_T	0.787	0.47
246_P	255_Q	0.786	0.47
214_V	266_L	0.786	0.47
554_I	557_I	0.786	0.47
215_I	273_S	0.786	0.47
79_K	123_S	0.785	0.47
74_I	263_L	0.784	0.47
422_A	429_Y	0.783	0.47
103_T	239_G	0.783	0.47
104_A	257_A	0.783	0.47
334_S	337_W	0.782	0.47
463_Q	466_Q	0.782	0.47
197_L	283_I	0.781	0.47
267_D	297_N	0.780	0.47
108_L	296_V	0.779	0.47
112_T	224_G	0.778	0.46
111_H	268_Y	0.778	0.46
268_Y	299_F	0.776	0.46
78_M	241_N	0.775	0.46
689_T	702_E	0.775	0.46
58_L	581_G	0.773	0.46
428_N	432_Q	0.772	0.46
579_F	653_Y	0.772	0.46
106_P	280_R	0.772	0.46
247_H	296_V	0.772	0.46
268_Y	276_D	0.771	0.46
639_Y	645_A	0.770	0.46
703_S	716_V	0.770	0.46
101_P	214_V	0.769	0.46
485_T	502_L	0.768	0.46
100_R	246_P	0.767	0.46
331_F	398_L	0.765	0.45
78_M	123_S	0.762	0.45
696_A	703_S	0.761	0.45
72_L	80_A	0.759	0.45
259_A	263_L	0.758	0.45
71_V	260_S	0.758	0.45
86_I	308_D	0.758	0.45
98_R	268_Y	0.757	0.45
99_N	269_T	0.757	0.45
94_V	222_L	0.756	0.45
255_Q	293_Y	0.756	0.45
593_S	597_S	0.754	0.44
98_R	237_T	0.754	0.44
95_L	104_A	0.750	0.44
266_L	302_Q	0.750	0.44
700_Q	706_R	0.749	0.44
252_L	273_S	0.748	0.44
214_V	246_P	0.748	0.44
95_L	102_M	0.747	0.44
78_M	294_V	0.746	0.44
76_G	82_K	0.743	0.43
101_P	287_G	0.741	0.43
70_M	235_L	0.740	0.43
495_Q	500_V	0.739	0.43
102_M	267_D	0.739	0.43
79_K	302_Q	0.737	0.43
80_A	268_Y	0.737	0.43
128_I	216_E	0.737	0.43
215_I	228_Y	0.737	0.43
297_N	339_Y	0.735	0.43
476_I	480_I	0.735	0.43
695_L	699_Q	0.732	0.43
235_L	244_G	0.731	0.42
686_E	690_R	0.731	0.42
241_N	261_A	0.731	0.42
74_I	79_K	0.731	0.42
426_L	646_L	0.729	0.42
409_A	413_N	0.729	0.42
430_A	502_L	0.729	0.42
237_T	240_P	0.727	0.42
270_Q	301_Q	0.726	0.42
697_L	708_M	0.724	0.42
78_M	244_G	0.724	0.42
105_L	267_D	0.724	0.42
85_T	107_T	0.723	0.42
249_Q	252_L	0.721	0.42
97_N	243_A	0.720	0.42
297_N	341_A	0.720	0.42
74_I	100_R	0.720	0.42
297_N	300_D	0.720	0.42
96_P	335_S	0.719	0.41
77_T	214_V	0.718	0.41
79_K	99_N	0.716	0.41
75_V	272_K	0.716	0.41
119_V	223_A	0.716	0.41
94_V	112_T	0.715	0.41
709_Q	714_Q	0.714	0.41
82_K	239_G	0.713	0.41
653_Y	661_L	0.713	0.41
86_I	257_A	0.713	0.41
237_T	268_Y	0.712	0.41
700_Q	710_Q	0.711	0.41
71_V	293_Y	0.709	0.41
73_A	302_Q	0.709	0.41
100_R	203_F	0.709	0.41
701_N	708_M	0.709	0.41
98_R	270_Q	0.707	0.40
174_Y	178_Q	0.707	0.40
75_V	266_L	0.706	0.40
102_M	215_I	0.705	0.40
77_T	257_A	0.704	0.40
705_V	708_M	0.703	0.40
467_L	566_S	0.701	0.40
228_Y	240_P	0.700	0.40
705_V	712_L	0.700	0.40
78_M	269_T	0.699	0.40
393_L	397_S	0.698	0.40
217_V	242_E	0.695	0.39
451_L	455_I	0.694	0.39
141_D	295_L	0.694	0.39
73_A	243_A	0.693	0.39
77_T	251_M	0.693	0.39
243_A	273_S	0.693	0.39
85_T	302_Q	0.692	0.39
122_F	217_V	0.691	0.39
296_V	302_Q	0.689	0.39
253_N	297_N	0.689	0.39
101_P	242_E	0.688	0.39
78_M	413_N	0.688	0.39
598_R	604_E	0.687	0.39
70_M	118_P	0.687	0.39
77_T	240_P	0.687	0.39
84_T	99_N	0.685	0.39
68_L	237_T	0.685	0.39
240_P	296_V	0.684	0.39
291_P	409_A	0.684	0.39
613_R	622_Q	0.684	0.39
77_T	86_I	0.684	0.39
78_M	262_V	0.684	0.39
195_K	199_V	0.684	0.39
249_Q	266_L	0.683	0.38
152_E	156_D	0.682	0.38
713_Q	717_M	0.681	0.38
176_G	179_P	0.680	0.38
700_Q	705_V	0.679	0.38
311_Q	314_A	0.679	0.38
341_A	394_W	0.677	0.38
91_G	101_P	0.675	0.38
505_L	508_D	0.673	0.38
272_K	291_P	0.672	0.38
282_A	286_V	0.672	0.38
123_S	269_T	0.672	0.38
232_L	263_L	0.670	0.37
28_E	32_L	0.670	0.37
490_F	507_Q	0.669	0.37
457_Q	531_I	0.666	0.37
299_F	332_P	0.664	0.37
266_L	269_T	0.664	0.37
177_A	181_F	0.662	0.37
73_A	235_L	0.661	0.37
314_A	317_S	0.660	0.37
240_P	406_L	0.660	0.37
604_E	607_T	0.660	0.37
123_S	128_I	0.659	0.36
77_T	297_N	0.659	0.36
434_R	438_D	0.657	0.36
109_I	240_P	0.656	0.36
710_Q	713_Q	0.656	0.36
678_A	681_A	0.655	0.36
578_V	583_V	0.655	0.36
524_L	620_L	0.654	0.36
268_Y	414_A	0.654	0.36
237_T	267_D	0.652	0.36
247_H	290_V	0.651	0.36
102_M	312_V	0.649	0.36
261_A	294_V	0.648	0.36
214_V	271_L	0.648	0.36
265_V	296_V	0.646	0.35
251_M	271_L	0.646	0.35
247_H	298_K	0.646	0.35
244_G	297_N	0.645	0.35
502_L	596_I	0.645	0.35
703_S	713_Q	0.645	0.35
247_H	328_Q	0.644	0.35
231_Q	252_L	0.644	0.35
106_P	259_A	0.643	0.35
120_L	124_H	0.643	0.35
123_S	237_T	0.643	0.35
104_A	325_I	0.643	0.35
489_H	496_D	0.643	0.35
107_T	422_A	0.642	0.35
664_Q	705_V	0.642	0.35
317_S	563_M	0.642	0.35
69_E	429_Y	0.640	0.35
75_V	279_V	0.640	0.35
79_K	241_N	0.640	0.35
80_A	269_T	0.639	0.35
490_F	496_D	0.639	0.35
293_Y	302_Q	0.638	0.35
576_F	582_V	0.638	0.35
104_A	270_Q	0.638	0.35
336_M	340_L	0.638	0.35
403_I	407_L	0.637	0.35
626_G	630_E	0.637	0.35
237_T	252_L	0.637	0.35
184_L	188_N	0.637	0.35
638_D	641_V	0.636	0.35
287_G	409_A	0.635	0.35
253_N	282_A	0.635	0.35
317_S	321_M	0.634	0.35
692_R	702_E	0.633	0.34
685_T	688_Q	0.632	0.34
404_Q	589_R	0.631	0.34
241_N	271_L	0.630	0.34
173_Y	176_G	0.629	0.34
489_H	492_R	0.628	0.34
123_S	276_D	0.626	0.34
298_K	329_Q	0.626	0.34
91_G	109_I	0.625	0.34
338_G	341_A	0.624	0.34
582_V	588_T	0.623	0.34
79_K	243_A	0.623	0.34
254_Q	258_R	0.621	0.33
342_N	394_W	0.621	0.33
176_G	184_L	0.620	0.33
452_R	561_V	0.619	0.33
94_V	659_K	0.619	0.33
37_D	41_Q	0.618	0.33
72_L	433_A	0.617	0.33
266_L	294_V	0.617	0.33
80_A	276_D	0.617	0.33
56_A	90_V	0.616	0.33
431_Q	481_E	0.616	0.33
98_R	231_Q	0.615	0.33
59_N	464_L	0.615	0.33
260_S	269_T	0.615	0.33
698_R	711_Q	0.613	0.33
73_A	255_Q	0.613	0.33
77_T	290_V	0.613	0.33
448_C	452_R	0.612	0.33
71_V	259_A	0.611	0.33
81_G	87_N	0.610	0.33
118_P	217_V	0.610	0.33
77_T	275_S	0.609	0.33
334_S	338_G	0.608	0.32
84_T	215_I	0.607	0.32
241_N	264_A	0.606	0.32
641_V	645_A	0.606	0.32
180_I	185_K	0.605	0.32
218_E	222_L	0.605	0.32
84_T	297_N	0.604	0.32
478_H	644_R	0.604	0.32
510_S	515_E	0.604	0.32
77_T	269_T	0.603	0.32
597_S	601_A	0.602	0.32
77_T	80_A	0.602	0.32
79_K	109_I	0.601	0.32
118_P	341_A	0.600	0.32
270_Q	298_K	0.600	0.32
597_S	603_D	0.599	0.32
42_L	640_S	0.599	0.32
251_M	260_S	0.598	0.32
247_H	266_L	0.598	0.32
252_L	260_S	0.598	0.32
155_K	160_L	0.598	0.32
595_V	600_E	0.597	0.32
215_I	251_M	0.596	0.32
157_M	166_N	0.596	0.32
648_A	656_Q	0.596	0.32
103_T	107_T	0.595	0.32
600_E	605_Q	0.595	0.32
76_G	89_I	0.592	0.31
78_M	272_K	0.590	0.31
399_F	403_I	0.589	0.31
582_V	587_N	0.589	0.31
284_L	287_G	0.588	0.31
76_G	244_G	0.587	0.31
86_I	210_E	0.586	0.31
36_G	573_G	0.586	0.31
96_P	227_S	0.585	0.31
71_V	297_N	0.585	0.31
333_V	395_E	0.581	0.30
493_Q	499_K	0.580	0.30
594_E	604_E	0.579	0.30
593_S	604_E	0.578	0.30
214_V	397_S	0.578	0.30
313_R	330_I	0.577	0.30
683_C	687_L	0.577	0.30
237_T	302_Q	0.576	0.30
77_T	268_Y	0.576	0.30
102_M	123_S	0.576	0.30
128_I	242_E	0.576	0.30
263_L	297_N	0.576	0.30
101_P	244_G	0.576	0.30
98_R	246_P	0.576	0.30
106_P	217_V	0.575	0.30
211_H	488_N	0.574	0.30
86_I	123_S	0.574	0.30
508_D	511_E	0.571	0.30
490_F	506_F	0.570	0.30
59_N	684_L	0.570	0.30
264_A	270_Q	0.569	0.30
706_R	709_Q	0.569	0.30
80_A	251_M	0.568	0.30
442_H	468_N	0.566	0.29
705_V	710_Q	0.566	0.29
106_P	247_H	0.565	0.29
34_V	37_D	0.565	0.29
707_L	714_Q	0.565	0.29
694_S	698_R	0.564	0.29
267_D	271_L	0.564	0.29
75_V	84_T	0.562	0.29
123_S	264_A	0.562	0.29
262_V	680_F	0.562	0.29
318_G	399_F	0.562	0.29
709_Q	713_Q	0.561	0.29
477_K	481_E	0.560	0.29
105_L	296_V	0.560	0.29
297_N	409_A	0.560	0.29
78_M	112_T	0.560	0.29
249_Q	291_P	0.559	0.29
283_I	699_Q	0.558	0.29
231_Q	414_A	0.558	0.29
479_E	483_A	0.558	0.29
76_G	236_D	0.557	0.29
526_T	530_T	0.556	0.29
77_T	298_K	0.555	0.29
640_S	644_R	0.555	0.29
702_E	708_M	0.555	0.29
180_I	187_L	0.554	0.29
100_R	266_L	0.554	0.29
43_A	163_R	0.553	0.28
78_M	84_T	0.552	0.28
98_R	296_V	0.552	0.28
242_E	255_Q	0.551	0.28
152_E	155_K	0.550	0.28
70_M	252_L	0.550	0.28
108_L	240_P	0.549	0.28
106_P	233_T	0.549	0.28
71_V	106_P	0.549	0.28
553_V	556_P	0.548	0.28
594_E	601_A	0.548	0.28
184_L	187_L	0.548	0.28
315_L	320_L	0.547	0.28
493_Q	504_A	0.547	0.28
111_H	410_A	0.546	0.28
328_Q	332_P	0.546	0.28
249_Q	267_D	0.545	0.28
81_G	238_P	0.543	0.28
492_R	497_A	0.542	0.28
280_R	406_L	0.541	0.28
109_I	237_T	0.541	0.28
240_P	251_M	0.540	0.28
109_I	406_L	0.539	0.27
77_T	302_Q	0.539	0.27
714_Q	717_M	0.539	0.27
620_L	627_R	0.539	0.27
32_L	465_L	0.537	0.27
687_L	702_E	0.537	0.27
78_M	228_Y	0.537	0.27
70_M	98_R	0.537	0.27
240_P	273_S	0.536	0.27
108_L	242_E	0.535	0.27
464_L	470_A	0.535	0.27
398_L	401_Q	0.534	0.27
338_G	398_L	0.533	0.27
298_K	308_D	0.531	0.27
96_P	266_L	0.530	0.27
598_R	601_A	0.530	0.27
78_M	118_P	0.530	0.27
492_R	502_L	0.530	0.27
693_E	696_A	0.528	0.27
231_Q	406_L	0.528	0.27
103_T	228_Y	0.527	0.27
704_V	708_M	0.527	0.27
249_Q	253_N	0.527	0.27
457_Q	460_E	0.527	0.27
563_M	566_S	0.527	0.27
423_A	483_A	0.527	0.27
59_N	63_R	0.526	0.27
90_V	418_A	0.526	0.27
101_P	247_H	0.524	0.26
271_L	299_F	0.524	0.26
34_V	38_D	0.523	0.26
76_G	112_T	0.523	0.26
100_R	252_L	0.523	0.26
494_Q	502_L	0.522	0.26
79_K	268_Y	0.521	0.26
86_I	287_G	0.520	0.26
71_V	107_T	0.518	0.26
256_L	511_E	0.518	0.26
123_S	208_A	0.518	0.26
223_A	271_L	0.518	0.26
311_Q	315_L	0.517	0.26
232_L	402_P	0.516	0.26
707_L	711_Q	0.515	0.26
100_R	247_H	0.515	0.26
104_A	297_N	0.515	0.26
579_F	586_F	0.515	0.26
297_N	338_G	0.515	0.26
271_L	297_N	0.514	0.26
243_A	276_D	0.513	0.26
85_T	232_L	0.513	0.26
214_V	255_Q	0.512	0.26
250_K	264_A	0.511	0.26
108_L	255_Q	0.511	0.26
664_Q	673_M	0.511	0.26
54_R	252_L	0.510	0.26
267_D	339_Y	0.510	0.26
111_H	231_Q	0.510	0.26
158_R	164_I	0.509	0.25
433_A	482_L	0.509	0.25
231_Q	235_L	0.509	0.25
437_L	712_L	0.508	0.25
232_L	293_Y	0.506	0.25
79_K	91_G	0.504	0.25
108_L	244_G	0.504	0.25
104_A	237_T	0.504	0.25
637_V	645_A	0.504	0.25
72_L	637_V	0.503	0.25
422_A	425_K	0.503	0.25
256_L	259_A	0.503	0.25
111_H	118_P	0.502	0.25
235_L	242_E	0.501	0.25
247_H	253_N	0.501	0.25
101_P	283_I	0.501	0.25
554_I	558_E	0.500	0.25
85_T	279_V	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2j69A	1	0.8208	100	0.633	Contact Map
4aurA	1	0.717	100	0.736	Contact Map
4uudA	5	0.6617	100	0.77	Contact Map
4bejA	2	0.7197	100	0.77	Contact Map
3w6pA	2	0.438	99.9	0.785	Contact Map
2akaB	1	0.3881	99.9	0.793	Contact Map
2x2eA	2	0.4353	99.9	0.798	Contact Map
3t34A	2	0.4461	99.9	0.801	Contact Map
3zvrA	1	0.6105	99.9	0.816	Contact Map
1jwyB	1	0.372	99.8	0.824	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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