INSD8 - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

INSD8 - Putative transposase InsD for insertion element IS2E

UniProt:	P0CF60	Sequences: MPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG40004
Length:	218 (193)
Sequences:	8231 (5537)
Seq/√Len:	398.6

ECOLI - INSD8 INSD1 INSD2 INSD3 INSD4 INSD5 INSD6 INSK INSF1 INSF2 INSF3 INSF4 INSF5 YAGA INSO2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
94_L	128_F	2.813	1.00
196_R	204_Q	2.794	1.00
65_F	154_V	2.654	1.00
186_E	199_R	2.639	1.00
41_E	44_Q	2.584	1.00
43_N	46_W	2.489	1.00
73_E	199_R	2.482	1.00
182_E	186_E	2.451	1.00
78_A	95_G	2.420	1.00
47_C	150_A	2.292	1.00
155_K	159_R	2.147	1.00
40_K	44_Q	2.089	1.00
48_S	114_T	2.072	1.00
169_D	172_T	1.975	1.00
5_N	8_R	1.966	1.00
197_S	200_E	1.944	1.00
73_E	202_L	1.944	1.00
167_K	176_N	1.927	1.00
196_R	201_Y	1.882	1.00
168_P	172_T	1.816	1.00
69_C	149_I	1.813	1.00
48_S	112_W	1.812	1.00
52_E	60_R	1.806	1.00
47_C	69_C	1.798	1.00
78_A	91_D	1.788	1.00
140_A	146_S	1.784	1.00
161_Y	176_N	1.710	1.00
126_R	136_P	1.679	1.00
51_F	158_K	1.677	1.00
160_D	188_H	1.665	1.00
48_S	120_Y	1.660	1.00
65_F	150_A	1.648	1.00
41_E	110_V	1.575	1.00
86_S	90_Q	1.540	1.00
129_A	136_P	1.536	1.00
46_W	96_A	1.528	1.00
129_A	134_L	1.525	1.00
44_Q	110_V	1.497	1.00
46_W	66_A	1.497	1.00
39_V	45_R	1.476	1.00
84_F	119_C	1.469	1.00
74_A	153_F	1.458	1.00
74_A	185_N	1.418	1.00
152_S	156_T	1.417	1.00
76_H	92_V	1.411	1.00
116_N	138_N	1.409	1.00
10_Y	14_R	1.409	1.00
63_V	157_I	1.399	1.00
64_T	120_Y	1.397	1.00
152_S	155_K	1.391	1.00
157_I	177_L	1.381	1.00
81_T	170_G	1.381	1.00
199_R	203_R	1.379	1.00
90_Q	128_F	1.375	1.00
8_R	11_R	1.353	1.00
113_L	137_K	1.349	1.00
12_I	16_N	1.349	1.00
61_L	170_G	1.346	1.00
50_G	119_C	1.343	1.00
43_N	100_R	1.331	1.00
128_F	132_L	1.316	1.00
72_R	190_H	1.309	1.00
64_T	92_V	1.292	1.00
71_D	202_L	1.285	1.00
161_Y	167_K	1.282	1.00
47_C	149_I	1.276	1.00
114_T	136_P	1.268	1.00
39_V	44_Q	1.265	1.00
139_T	147_N	1.260	1.00
173_A	177_L	1.259	1.00
116_N	141_V	1.258	1.00
54_C	60_R	1.253	1.00
48_S	66_A	1.237	1.00
97_V	132_L	1.235	1.00
193_L	201_Y	1.232	1.00
182_E	187_W	1.201	1.00
97_V	134_L	1.195	1.00
110_V	134_L	1.191	1.00
174_A	178_A	1.182	1.00
170_G	174_A	1.179	1.00
176_N	179_E	1.179	1.00
31_R	34_T	1.176	1.00
145_E	148_G	1.170	1.00
74_A	181_F	1.163	1.00
7_K	10_Y	1.152	1.00
80_T	88_T	1.149	1.00
55_C	58_G	1.145	1.00
86_S	122_A	1.139	1.00
85_N	88_T	1.134	1.00
86_S	124_E	1.131	1.00
197_S	201_Y	1.118	1.00
42_S	70_C	1.109	1.00
66_A	92_V	1.108	1.00
127_Q	131_M	1.106	1.00
172_T	176_N	1.088	1.00
52_E	62_R	1.083	1.00
90_Q	124_E	1.063	1.00
42_S	71_D	1.056	1.00
8_R	12_I	1.052	1.00
66_A	96_A	1.052	1.00
140_A	143_S	1.049	1.00
113_L	146_S	1.046	1.00
123_N	127_Q	1.042	1.00
178_A	182_E	1.032	1.00
191_S	195_Y	1.031	1.00
45_R	111_E	1.022	1.00
193_L	197_S	1.013	1.00
121_R	138_N	1.008	1.00
67_L	74_A	1.005	1.00
165_M	176_N	1.005	1.00
196_R	200_E	1.000	1.00
150_A	154_V	1.000	1.00
63_V	77_W	0.992	1.00
61_L	173_A	0.991	1.00
64_T	88_T	0.991	1.00
83_G	88_T	0.986	1.00
72_R	192_A	0.977	1.00
41_E	70_C	0.976	1.00
84_F	118_S	0.969	1.00
112_W	134_L	0.965	1.00
72_R	149_I	0.963	1.00
112_W	125_T	0.942	1.00
45_R	69_C	0.936	1.00
6_A	10_Y	0.931	1.00
118_S	122_A	0.930	1.00
67_L	149_I	0.929	1.00
114_T	138_N	0.925	1.00
139_T	146_S	0.915	1.00
79_V	174_A	0.914	1.00
111_E	137_K	0.914	1.00
50_G	84_F	0.909	1.00
7_K	11_R	0.905	1.00
56_D	166_P	0.905	1.00
90_Q	94_L	0.903	1.00
43_N	202_L	0.902	1.00
77_W	178_A	0.899	1.00
87_E	124_E	0.898	1.00
73_E	100_R	0.895	1.00
67_L	150_A	0.894	1.00
183_H	187_W	0.891	1.00
65_F	153_F	0.891	1.00
118_S	121_R	0.887	1.00
63_V	79_V	0.882	1.00
153_F	157_I	0.874	1.00
111_E	135_E	0.872	1.00
87_E	91_D	0.871	1.00
76_H	95_G	0.865	1.00
189_P	195_Y	0.850	1.00
126_R	130_R	0.835	1.00
29_S	136_P	0.832	1.00
46_W	110_V	0.830	1.00
200_E	203_R	0.827	1.00
13_M	18_L	0.817	1.00
93_M	112_W	0.816	1.00
71_D	201_Y	0.812	1.00
80_T	85_N	0.809	1.00
48_S	64_T	0.801	1.00
116_N	121_R	0.793	1.00
12_I	15_Q	0.788	1.00
5_N	11_R	0.786	1.00
46_W	109_P	0.785	1.00
190_H	193_L	0.781	1.00
100_R	202_L	0.778	1.00
89_V	125_T	0.770	1.00
119_C	122_A	0.769	1.00
16_N	19_L	0.768	1.00
200_E	204_Q	0.766	1.00
106_P	109_P	0.763	1.00
161_Y	180_A	0.753	1.00
201_Y	204_Q	0.750	1.00
128_F	131_M	0.748	1.00
39_V	70_C	0.747	1.00
30_K	34_T	0.747	1.00
95_G	99_R	0.741	1.00
32_A	135_E	0.741	1.00
52_E	84_F	0.740	1.00
14_R	19_L	0.740	1.00
94_L	98_E	0.739	1.00
160_D	180_A	0.738	1.00
76_H	96_A	0.737	1.00
45_R	113_L	0.733	1.00
153_F	184_Y	0.729	1.00
172_T	175_K	0.728	1.00
11_R	15_Q	0.720	1.00
124_E	128_F	0.720	1.00
75_L	96_A	0.715	1.00
36_R	45_R	0.714	1.00
33_H	45_R	0.710	1.00
64_T	89_V	0.707	1.00
153_F	181_F	0.707	1.00
125_T	129_A	0.707	1.00
122_A	125_T	0.704	1.00
39_V	69_C	0.703	1.00
10_Y	19_L	0.702	1.00
167_K	173_A	0.702	1.00
113_L	139_T	0.697	1.00
21_E	25_A	0.694	1.00
29_S	32_A	0.690	1.00
53_F	177_L	0.689	1.00
127_Q	130_R	0.688	1.00
47_C	147_N	0.685	0.99
67_L	72_R	0.684	0.99
181_F	185_N	0.682	0.99
50_G	62_R	0.682	0.99
156_T	180_A	0.678	0.99
50_G	64_T	0.675	0.99
94_L	132_L	0.666	0.99
77_W	181_F	0.664	0.99
19_L	22_R	0.662	0.99
92_V	96_A	0.661	0.99
161_Y	177_L	0.659	0.99
53_F	162_I	0.657	0.99
156_T	190_H	0.655	0.99
100_R	107_S	0.651	0.99
143_S	146_S	0.647	0.99
124_E	127_Q	0.639	0.99
20_L	23_K	0.638	0.99
57_N	170_G	0.637	0.99
56_D	168_P	0.632	0.99
139_T	142_R	0.631	0.99
80_T	84_F	0.627	0.99
78_A	92_V	0.624	0.99
53_F	173_A	0.618	0.99
84_F	88_T	0.618	0.99
65_F	74_A	0.615	0.99
112_W	129_A	0.613	0.99
87_E	90_Q	0.612	0.99
114_T	125_T	0.607	0.99
46_W	75_L	0.601	0.99
55_C	61_L	0.601	0.99
93_M	125_T	0.601	0.99
46_W	100_R	0.600	0.99
23_K	159_R	0.594	0.99
62_R	84_F	0.594	0.99
93_M	129_A	0.594	0.99
53_F	63_V	0.587	0.98
177_L	181_F	0.586	0.98
125_T	136_P	0.586	0.98
55_C	170_G	0.578	0.98
67_L	153_F	0.576	0.98
78_A	88_T	0.576	0.98
28_P	31_R	0.574	0.98
84_F	89_V	0.574	0.98
21_E	164_I	0.573	0.98
63_V	177_L	0.572	0.98
47_C	113_L	0.571	0.98
184_Y	190_H	0.569	0.98
154_V	180_A	0.567	0.98
43_N	96_A	0.564	0.98
156_T	184_Y	0.563	0.98
51_F	154_V	0.562	0.98
137_K	146_S	0.561	0.98
5_N	10_Y	0.560	0.98
184_Y	188_H	0.559	0.98
73_E	186_E	0.555	0.98
30_K	33_H	0.551	0.98
79_V	177_L	0.550	0.98
91_D	94_L	0.547	0.98
73_E	99_R	0.546	0.98
162_I	167_K	0.544	0.97
78_A	174_A	0.543	0.97
113_L	147_N	0.542	0.97
126_R	138_N	0.541	0.97
62_R	119_C	0.536	0.97
150_A	153_F	0.536	0.97
97_V	108_S	0.536	0.97
171_L	174_A	0.534	0.97
50_G	89_V	0.531	0.97
12_I	18_L	0.531	0.97
93_M	134_L	0.530	0.97
86_S	118_S	0.529	0.97
193_L	196_R	0.525	0.97
31_R	37_V	0.525	0.97
80_T	174_A	0.524	0.97
186_E	203_R	0.524	0.97
141_V	144_P	0.521	0.97
123_N	126_R	0.520	0.97
159_R	163_S	0.519	0.97
13_M	20_L	0.518	0.97
144_P	154_V	0.513	0.96
47_C	67_L	0.513	0.96
112_W	136_P	0.511	0.96
55_C	173_A	0.511	0.96
144_P	148_G	0.509	0.96
93_M	128_F	0.505	0.96
10_Y	20_L	0.505	0.96
35_G	145_E	0.503	0.96
69_C	72_R	0.503	0.96
158_K	163_S	0.500	0.96
89_V	112_W	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1bcoA	1	0.7936	100	0.399	Contact Map
4fcyA	4	0.922	100	0.401	Contact Map
3oymA	3	0.9312	100	0.414	Contact Map
4cf8A	2	0.6835	100	0.424	Contact Map
3kksA	2	0.6972	100	0.424	Contact Map
3f9kA	5	0.8257	100	0.431	Contact Map
1k6yA	4	0.7661	100	0.431	Contact Map
1c6vA	4	0.6835	100	0.433	Contact Map
3l3uA	2	0.7018	100	0.433	Contact Map
1ex4A	5	0.7248	100	0.438	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0085 seconds.