EPTC - ECOLI - GREMLIN Contacts

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EPTC - Phosphoethanolamine transferase EptC

UniProt:	P0CB39	Sequences: MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALLYGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLNDPAPKKLIIVHLLGTHIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAANPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYDTLPYGDQVGNQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11914
Length:	577 (497)
Sequences:	5303 (4503)
Seq/√Len:	202.0

ECOLI - EPTC YHBX EPTA EPTB OPGE YEJM YJGX
BACSU - LTAS2 YQGS LTAS1 YVGJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
264_E	441_A	5.957	1.00
279_N	512_D	5.456	1.00
318_K	344_S	4.721	1.00
377_N	450_A	4.255	1.00
526_D	540_S	4.200	1.00
264_E	267_A	3.908	1.00
29_T	32_Q	3.640	1.00
260_E	266_D	3.382	1.00
373_Q	446_D	3.362	1.00
242_V	458_Y	3.293	1.00
441_A	445_K	3.292	1.00
323_K	381_P	3.196	1.00
240_V	456_L	3.174	1.00
515_Y	541_V	2.973	1.00
445_K	448_K	2.933	1.00
239_L	317_M	2.837	1.00
281_V	515_Y	2.715	1.00
244_G	247_T	2.698	1.00
253_S	262_T	2.669	1.00
238_T	454_G	2.651	1.00
239_L	528_A	2.638	1.00
523_T	542_V	2.607	1.00
237_R	453_N	2.590	1.00
274_N	448_K	2.415	1.00
317_M	528_A	2.345	1.00
137_L	141_R	2.276	1.00
444_I	456_L	2.239	1.00
371_P	374_E	2.202	1.00
447_F	456_L	2.191	1.00
136_V	140_T	2.186	1.00
297_T	312_S	2.160	1.00
445_K	449_A	2.153	1.00
336_R	340_L	2.139	1.00
255_Y	277_V	2.101	1.00
240_V	454_G	2.092	1.00
336_R	339_M	2.067	1.00
238_T	383_K	2.054	1.00
401_P	435_Y	2.048	1.00
442_S	445_K	2.044	1.00
241_L	384_L	2.033	1.00
262_T	266_D	2.029	1.00
193_A	197_Q	2.025	1.00
32_Q	36_Y	2.019	1.00
29_T	33_A	1.948	1.00
189_R	193_A	1.933	1.00
373_Q	450_A	1.930	1.00
190_M	193_A	1.923	1.00
484_R	487_Y	1.897	1.00
242_V	440_V	1.883	1.00
32_Q	35_I	1.882	1.00
27_F	32_Q	1.877	1.00
333_M	336_R	1.875	1.00
369_L	373_Q	1.872	1.00
366_T	442_S	1.856	1.00
235_E	453_N	1.849	1.00
348_D	351_Y	1.844	1.00
455_F	493_L	1.838	1.00
288_T	388_H	1.826	1.00
495_T	498_K	1.815	1.00
192_P	195_P	1.797	1.00
372_F	387_V	1.795	1.00
241_L	457_V	1.792	1.00
406_K	434_L	1.789	1.00
365_D	369_L	1.788	1.00
189_R	192_P	1.763	1.00
393_H	461_D	1.732	1.00
28_S	32_Q	1.728	1.00
295_A	459_F	1.720	1.00
392_T	432_A	1.684	1.00
247_T	433_N	1.682	1.00
443_L	456_L	1.638	1.00
189_R	194_A	1.629	1.00
263_P	437_D	1.621	1.00
85_A	95_E	1.604	1.00
33_A	36_Y	1.601	1.00
279_N	510_D	1.598	1.00
373_Q	377_N	1.597	1.00
26_F	32_Q	1.587	1.00
457_V	493_L	1.574	1.00
337_N	341_T	1.559	1.00
253_S	260_E	1.554	1.00
434_L	438_H	1.513	1.00
327_I	375_V	1.510	1.00
334_T	337_N	1.502	1.00
491_F	520_L	1.495	1.00
41_S	44_N	1.481	1.00
438_H	442_S	1.479	1.00
265_L	440_V	1.478	1.00
369_L	389_L	1.474	1.00
151_W	154_V	1.473	1.00
446_D	450_A	1.463	1.00
366_T	435_Y	1.460	1.00
27_F	30_L	1.459	1.00
253_S	266_D	1.453	1.00
191_E	194_A	1.453	1.00
402_E	405_G	1.444	1.00
483_T	486_M	1.441	1.00
32_Q	38_S	1.440	1.00
243_I	292_L	1.438	1.00
198_F	201_G	1.438	1.00
192_P	201_G	1.438	1.00
45_G	49_S	1.425	1.00
459_F	517_L	1.423	1.00
333_M	337_N	1.420	1.00
244_G	458_Y	1.415	1.00
275_L	494_W	1.410	1.00
25_W	32_Q	1.407	1.00
244_G	436_N	1.407	1.00
264_E	444_I	1.403	1.00
194_A	197_Q	1.393	1.00
439_V	442_S	1.383	1.00
108_N	111_E	1.382	1.00
325_F	383_K	1.376	1.00
237_R	455_F	1.375	1.00
368_V	387_V	1.373	1.00
133_A	137_L	1.370	1.00
338_T	341_T	1.368	1.00
199_L	203_Y	1.364	1.00
161_Y	165_L	1.362	1.00
247_T	436_N	1.361	1.00
446_D	449_A	1.359	1.00
405_G	408_D	1.351	1.00
238_T	452_P	1.347	1.00
298_F	522_H	1.343	1.00
149_K	152_R	1.342	1.00
392_T	433_N	1.338	1.00
259_R	430_D	1.338	1.00
192_P	196_W	1.337	1.00
239_L	455_F	1.336	1.00
460_S	489_I	1.336	1.00
197_Q	201_G	1.327	1.00
46_I	49_S	1.325	1.00
125_V	129_L	1.319	1.00
334_T	339_M	1.314	1.00
202_Y	206_R	1.313	1.00
281_V	491_F	1.312	1.00
267_A	441_A	1.309	1.00
316_M	525_S	1.306	1.00
45_G	48_D	1.306	1.00
44_N	47_R	1.288	1.00
335_A	339_M	1.286	1.00
25_W	33_A	1.280	1.00
249_R	488_T	1.278	1.00
251_R	430_D	1.272	1.00
422_E	427_N	1.266	1.00
29_T	36_Y	1.254	1.00
112_A	115_Y	1.251	1.00
244_G	440_V	1.251	1.00
404_Q	438_H	1.248	1.00
215_L	218_E	1.243	1.00
327_I	385_I	1.242	1.00
221_A	224_P	1.242	1.00
192_P	197_Q	1.238	1.00
438_H	441_A	1.236	1.00
442_S	446_D	1.221	1.00
377_N	446_D	1.215	1.00
243_I	459_F	1.206	1.00
247_T	265_L	1.205	1.00
197_Q	200_T	1.203	1.00
262_T	265_L	1.198	1.00
185_N	188_S	1.197	1.00
132_T	136_V	1.196	1.00
247_T	252_M	1.194	1.00
194_A	198_F	1.194	1.00
32_Q	39_G	1.184	1.00
191_E	196_W	1.181	1.00
186_L	189_R	1.180	1.00
497_E	500_Q	1.178	1.00
313_L	524_W	1.176	1.00
25_W	29_T	1.174	1.00
199_L	202_Y	1.167	1.00
40_Y	45_G	1.165	1.00
222_L	225_L	1.160	1.00
214_K	218_E	1.159	1.00
65_K	68_K	1.146	1.00
241_L	295_A	1.146	1.00
27_F	31_L	1.143	1.00
439_V	443_L	1.141	1.00
484_R	488_T	1.139	1.00
278_F	491_F	1.137	1.00
247_T	251_R	1.135	1.00
268_L	444_I	1.133	1.00
239_L	384_L	1.129	1.00
185_N	192_P	1.128	1.00
150_P	153_Y	1.124	1.00
185_N	189_R	1.123	1.00
332_T	337_N	1.122	1.00
276_T	511_V	1.119	1.00
444_I	448_K	1.118	1.00
457_V	524_W	1.114	1.00
248_Q	251_R	1.113	1.00
247_T	262_T	1.113	1.00
33_A	37_I	1.110	1.00
16_A	27_F	1.109	1.00
280_N	514_K	1.109	1.00
41_S	47_R	1.108	1.00
264_E	445_K	1.103	1.00
326_W	340_L	1.102	1.00
276_T	509_Q	1.099	1.00
47_R	50_L	1.097	1.00
150_P	154_V	1.095	1.00
201_G	205_Y	1.092	1.00
223_P	226_A	1.089	1.00
328_T	336_R	1.088	1.00
192_P	202_Y	1.088	1.00
322_Y	382_K	1.087	1.00
337_N	340_L	1.086	1.00
455_F	495_T	1.086	1.00
325_F	385_I	1.085	1.00
190_M	194_A	1.073	1.00
200_T	203_Y	1.072	1.00
21_L	29_T	1.071	1.00
392_T	436_N	1.067	1.00
295_A	520_L	1.062	1.00
326_W	388_H	1.059	1.00
135_A	139_W	1.055	1.00
195_P	200_T	1.053	1.00
248_Q	254_L	1.052	1.00
136_V	139_W	1.050	1.00
332_T	348_D	1.050	1.00
52_F	59_P	1.046	1.00
249_R	255_Y	1.044	1.00
248_Q	463_G	1.043	1.00
221_A	225_L	1.042	1.00
213_T	218_E	1.042	1.00
205_Y	208_Q	1.041	1.00
188_S	191_E	1.039	1.00
189_R	197_Q	1.039	1.00
369_L	443_L	1.039	1.00
455_F	524_W	1.039	1.00
188_S	192_P	1.038	1.00
243_I	386_I	1.038	1.00
200_T	204_Q	1.037	1.00
195_P	202_Y	1.037	1.00
46_I	50_L	1.034	1.00
44_N	49_S	1.034	1.00
335_A	338_T	1.034	1.00
32_Q	37_I	1.029	1.00
25_W	36_Y	1.022	1.00
222_L	226_A	1.022	1.00
26_F	29_T	1.021	1.00
219_N	222_L	1.020	1.00
288_T	393_H	1.019	1.00
370_K	442_S	1.019	1.00
323_K	345_R	1.019	1.00
21_L	24_F	1.018	1.00
24_F	32_Q	1.016	1.00
191_E	197_Q	1.012	1.00
189_R	196_W	1.009	1.00
266_D	269_H	1.009	1.00
376_L	447_F	1.008	1.00
41_S	45_G	1.008	1.00
29_T	38_S	1.007	1.00
264_E	438_H	1.002	1.00
371_P	375_V	0.999	1.00
25_W	28_S	0.998	1.00
214_K	217_N	0.996	1.00
148_P	151_W	0.993	1.00
251_R	433_N	0.992	1.00
76_V	80_A	0.990	1.00
191_E	195_P	0.989	1.00
245_E	461_D	0.988	1.00
276_T	542_V	0.988	1.00
196_W	199_L	0.987	1.00
362_R	390_L	0.987	1.00
333_M	339_M	0.986	1.00
321_G	382_K	0.986	1.00
151_W	155_V	0.983	1.00
178_P	181_K	0.983	1.00
268_L	440_V	0.983	1.00
193_A	196_W	0.982	1.00
42_G	46_I	0.982	1.00
267_A	274_N	0.982	1.00
51_L	55_L	0.981	1.00
400_Y	431_N	0.981	1.00
325_F	345_R	0.978	1.00
194_A	201_G	0.970	1.00
275_L	492_L	0.969	0.99
240_V	383_K	0.968	0.99
195_P	198_F	0.965	0.99
196_W	201_G	0.965	0.99
195_P	199_L	0.965	0.99
525_S	530_L	0.962	0.99
53_S	57_L	0.960	0.99
397_K	428_D	0.960	0.99
213_T	217_N	0.957	0.99
372_F	376_L	0.955	0.99
173_F	177_K	0.951	0.99
241_L	386_I	0.950	0.99
317_M	525_S	0.949	0.99
269_H	273_P	0.947	0.99
162_G	165_L	0.947	0.99
161_Y	164_I	0.945	0.99
220_N	223_P	0.942	0.99
311_P	319_Q	0.942	0.99
43_T	49_S	0.942	0.99
158_A	162_G	0.940	0.99
62_L	66_R	0.939	0.99
401_P	404_Q	0.937	0.99
177_K	180_E	0.934	0.99
257_Y	430_D	0.934	0.99
483_T	487_Y	0.929	0.99
230_D	542_V	0.929	0.99
164_I	168_I	0.924	0.99
264_E	437_D	0.923	0.99
178_P	184_D	0.922	0.99
21_L	25_W	0.921	0.99
211_S	215_L	0.920	0.99
333_M	340_L	0.919	0.99
440_V	458_Y	0.916	0.99
284_S	516_S	0.914	0.99
23_Y	27_F	0.913	0.99
479_E	482_P	0.912	0.99
407_F	427_N	0.912	0.99
243_I	295_A	0.911	0.99
212_L	218_E	0.911	0.99
30_L	36_Y	0.908	0.99
325_F	375_V	0.907	0.99
242_V	369_L	0.907	0.99
280_N	488_T	0.903	0.99
35_I	39_G	0.903	0.99
19_W	27_F	0.902	0.99
232_S	236_P	0.899	0.99
54_S	58_I	0.898	0.99
164_I	167_P	0.897	0.99
43_T	47_R	0.896	0.99
459_F	520_L	0.895	0.99
282_V	488_T	0.894	0.99
324_T	344_S	0.890	0.99
237_R	382_K	0.888	0.99
53_S	56_W	0.884	0.99
195_P	203_Y	0.884	0.99
372_F	385_I	0.881	0.99
57_L	63_F	0.881	0.99
18_G	22_L	0.881	0.99
29_T	34_I	0.880	0.99
284_S	294_Q	0.878	0.99
189_R	201_G	0.878	0.99
522_H	538_T	0.877	0.99
239_L	457_V	0.876	0.99
252_M	255_Y	0.875	0.99
240_V	376_L	0.875	0.99
387_V	443_L	0.870	0.99
168_I	172_T	0.869	0.99
370_K	446_D	0.867	0.99
213_T	216_L	0.866	0.99
24_F	27_F	0.866	0.99
250_G	485_H	0.865	0.99
180_E	183_L	0.864	0.99
171_N	174_I	0.862	0.99
198_F	205_Y	0.861	0.99
20_A	32_Q	0.861	0.99
367_N	370_K	0.861	0.99
342_V	348_D	0.856	0.99
265_L	492_L	0.851	0.99
245_E	393_H	0.850	0.99
41_S	49_S	0.849	0.99
190_M	201_G	0.847	0.99
365_D	368_V	0.846	0.99
241_L	459_F	0.846	0.99
26_F	30_L	0.846	0.99
296_L	384_L	0.845	0.99
482_P	486_M	0.843	0.99
192_P	200_T	0.837	0.99
80_A	84_A	0.834	0.98
389_L	436_N	0.834	0.98
26_F	36_Y	0.833	0.98
155_V	158_A	0.831	0.98
170_M	174_I	0.830	0.98
241_L	520_L	0.829	0.98
458_Y	492_L	0.828	0.98
113_S	117_S	0.827	0.98
20_A	24_F	0.825	0.98
30_L	33_A	0.825	0.98
186_L	192_P	0.821	0.98
28_S	31_L	0.820	0.98
172_T	176_N	0.818	0.98
407_F	434_L	0.817	0.98
160_L	163_L	0.816	0.98
18_G	21_L	0.815	0.98
343_F	386_I	0.813	0.98
29_T	35_I	0.813	0.98
219_N	223_P	0.812	0.98
268_L	492_L	0.808	0.98
298_F	310_Q	0.807	0.98
212_L	216_L	0.804	0.98
27_F	36_Y	0.804	0.98
404_Q	435_Y	0.803	0.98
376_L	385_I	0.802	0.98
288_T	461_D	0.801	0.98
344_S	348_D	0.800	0.98
269_H	275_L	0.800	0.98
239_L	322_Y	0.800	0.98
185_N	194_A	0.800	0.98
452_P	497_E	0.798	0.98
289_I	334_T	0.798	0.98
69_I	73_V	0.798	0.98
334_T	340_L	0.798	0.98
175_K	179_F	0.795	0.98
71_A	74_I	0.795	0.98
133_A	136_V	0.794	0.98
317_M	384_L	0.794	0.98
243_I	388_H	0.794	0.98
122_L	126_L	0.794	0.98
31_L	34_I	0.793	0.98
193_A	200_T	0.792	0.98
249_R	252_M	0.792	0.98
41_S	46_I	0.792	0.98
189_R	200_T	0.781	0.98
195_P	205_Y	0.780	0.98
244_G	369_L	0.780	0.98
391_G	435_Y	0.780	0.98
24_F	34_I	0.780	0.98
90_V	124_I	0.778	0.98
440_V	456_L	0.777	0.98
316_M	319_Q	0.776	0.98
264_E	268_L	0.776	0.98
242_V	456_L	0.775	0.98
288_T	292_L	0.772	0.97
396_Y	464_E	0.771	0.97
125_V	128_A	0.765	0.97
20_A	36_Y	0.763	0.97
31_L	35_I	0.760	0.97
265_L	433_N	0.759	0.97
173_F	180_E	0.759	0.97
180_E	184_D	0.758	0.97
203_Y	207_Q	0.756	0.97
27_F	34_I	0.754	0.97
326_W	330_Q	0.753	0.97
43_T	48_D	0.752	0.97
33_A	39_G	0.751	0.97
336_R	341_T	0.751	0.97
366_T	438_H	0.750	0.97
210_N	213_T	0.750	0.97
109_T	113_S	0.749	0.97
33_A	38_S	0.749	0.97
203_Y	206_R	0.748	0.97
111_E	115_Y	0.747	0.97
367_N	371_P	0.747	0.97
366_T	370_K	0.747	0.97
201_G	204_Q	0.746	0.97
20_A	34_I	0.746	0.97
328_T	334_T	0.744	0.97
318_K	324_T	0.743	0.97
268_L	458_Y	0.741	0.97
247_T	458_Y	0.741	0.97
42_G	47_R	0.741	0.97
40_Y	49_S	0.740	0.97
191_E	203_Y	0.739	0.97
193_A	198_F	0.738	0.97
52_F	55_L	0.736	0.97
34_I	39_G	0.734	0.97
212_L	215_L	0.734	0.97
20_A	28_S	0.734	0.97
369_L	436_N	0.732	0.97
200_T	206_R	0.731	0.97
167_P	172_T	0.729	0.96
314_M	343_F	0.728	0.96
169_A	172_T	0.725	0.96
352_Y	371_P	0.725	0.96
27_F	38_S	0.724	0.96
391_G	432_A	0.724	0.96
490_P	493_L	0.724	0.96
42_G	45_G	0.722	0.96
21_L	32_Q	0.722	0.96
421_E	424_E	0.719	0.96
177_K	181_K	0.719	0.96
188_S	193_A	0.717	0.96
85_A	96_F	0.717	0.96
128_A	132_T	0.713	0.96
175_K	178_P	0.712	0.96
469_T	485_H	0.712	0.96
57_L	60_V	0.712	0.96
190_M	200_T	0.711	0.96
427_N	431_N	0.711	0.96
322_Y	528_A	0.709	0.96
369_L	439_V	0.708	0.96
521_I	525_S	0.708	0.96
429_Y	433_N	0.707	0.96
20_A	27_F	0.706	0.96
393_H	462_H	0.705	0.96
111_E	116_L	0.704	0.96
431_N	434_L	0.704	0.96
326_W	329_N	0.702	0.96
167_P	171_N	0.699	0.96
174_I	181_K	0.698	0.95
216_L	219_N	0.697	0.95
212_L	217_N	0.696	0.95
374_E	446_D	0.691	0.95
174_I	178_P	0.690	0.95
28_S	37_I	0.686	0.95
263_P	266_D	0.684	0.95
335_A	340_L	0.684	0.95
31_L	37_I	0.684	0.95
236_P	320_A	0.681	0.95
194_A	199_L	0.681	0.95
43_T	46_I	0.680	0.95
444_I	458_Y	0.680	0.95
400_Y	405_G	0.678	0.95
28_S	33_A	0.678	0.95
186_L	191_E	0.675	0.95
336_R	346_Q	0.674	0.95
20_A	30_L	0.674	0.95
16_A	19_W	0.673	0.95
278_F	282_V	0.673	0.95
18_G	32_Q	0.673	0.95
141_R	144_P	0.672	0.94
190_M	195_P	0.671	0.94
36_Y	39_G	0.671	0.94
16_A	32_Q	0.669	0.94
57_L	61_F	0.668	0.94
188_S	196_W	0.668	0.94
452_P	496_S	0.667	0.94
35_I	38_S	0.667	0.94
175_K	182_T	0.667	0.94
28_S	34_I	0.666	0.94
374_E	377_N	0.664	0.94
196_W	200_T	0.663	0.94
389_L	439_V	0.662	0.94
224_P	228_F	0.661	0.94
269_H	277_V	0.661	0.94
405_G	409_G	0.661	0.94
22_L	32_Q	0.660	0.94
160_L	164_I	0.660	0.94
320_A	530_L	0.659	0.94
123_K	127_I	0.658	0.94
191_E	200_T	0.657	0.94
357_R	360_S	0.656	0.94
370_K	373_Q	0.655	0.94
138_L	141_R	0.655	0.94
27_F	37_I	0.653	0.94
17_L	29_T	0.652	0.94
127_I	131_Y	0.651	0.93
77_V	81_A	0.650	0.93
241_L	313_L	0.650	0.93
485_H	488_T	0.650	0.93
239_L	524_W	0.648	0.93
54_S	57_L	0.647	0.93
153_Y	164_I	0.646	0.93
277_V	510_D	0.646	0.93
261_T	430_D	0.644	0.93
491_F	515_Y	0.644	0.93
190_M	197_Q	0.644	0.93
198_F	203_Y	0.644	0.93
185_N	190_M	0.644	0.93
323_K	344_S	0.642	0.93
192_P	198_F	0.641	0.93
26_F	33_A	0.639	0.93
247_T	392_T	0.639	0.93
265_L	277_V	0.638	0.93
40_Y	46_I	0.638	0.93
489_I	517_L	0.637	0.93
186_L	190_M	0.634	0.93
29_T	39_G	0.633	0.93
344_S	347_T	0.632	0.92
288_T	462_H	0.632	0.92
345_R	348_D	0.632	0.92
187_A	190_M	0.631	0.92
60_V	63_F	0.629	0.92
56_W	59_P	0.629	0.92
249_R	277_V	0.629	0.92
269_H	274_N	0.628	0.92
199_L	206_R	0.627	0.92
240_V	443_L	0.627	0.92
109_T	116_L	0.627	0.92
195_P	201_G	0.627	0.92
185_N	193_A	0.626	0.92
198_F	207_Q	0.625	0.92
283_T	463_G	0.625	0.92
436_N	439_V	0.625	0.92
224_P	227_N	0.622	0.92
108_N	116_L	0.620	0.92
481_N	484_R	0.619	0.92
177_K	183_L	0.618	0.92
237_R	322_Y	0.618	0.92
217_N	220_N	0.618	0.92
330_Q	390_L	0.617	0.92
329_N	361_A	0.617	0.92
263_P	268_L	0.617	0.92
54_S	61_F	0.616	0.92
25_W	34_I	0.616	0.92
192_P	203_Y	0.615	0.91
196_W	203_Y	0.615	0.91
155_V	159_L	0.615	0.91
31_L	39_G	0.615	0.91
52_F	56_W	0.614	0.91
159_L	163_L	0.614	0.91
28_S	36_Y	0.612	0.91
146_Y	149_K	0.611	0.91
330_Q	388_H	0.611	0.91
306_L	310_Q	0.611	0.91
464_E	486_M	0.610	0.91
63_F	66_R	0.610	0.91
30_L	34_I	0.609	0.91
238_T	455_F	0.608	0.91
187_A	192_P	0.608	0.91
400_Y	404_Q	0.607	0.91
137_L	140_T	0.607	0.91
145_V	148_P	0.607	0.91
22_L	27_F	0.606	0.91
20_A	26_F	0.606	0.91
31_L	36_Y	0.605	0.91
179_F	182_T	0.601	0.90
256_G	430_D	0.601	0.90
199_L	205_Y	0.601	0.90
188_S	194_A	0.600	0.90
510_D	513_R	0.599	0.90
29_T	37_I	0.594	0.90
22_L	25_W	0.593	0.90
198_F	202_Y	0.592	0.90
248_Q	256_G	0.589	0.90
400_Y	432_A	0.588	0.90
314_M	324_T	0.588	0.90
482_P	485_H	0.586	0.89
100_V	103_V	0.586	0.89
130_A	134_V	0.585	0.89
215_L	219_N	0.584	0.89
211_S	218_E	0.584	0.89
19_W	29_T	0.583	0.89
251_R	255_Y	0.583	0.89
189_R	198_F	0.582	0.89
329_N	390_L	0.581	0.89
157_F	160_L	0.581	0.89
260_E	263_P	0.581	0.89
56_W	61_F	0.580	0.89
217_N	221_A	0.579	0.89
185_N	200_T	0.577	0.89
24_F	29_T	0.577	0.89
88_Y	290_E	0.577	0.89
279_N	511_V	0.576	0.89
355_Q	358_T	0.576	0.89
292_L	328_T	0.575	0.88
53_S	59_P	0.574	0.88
140_T	143_R	0.573	0.88
196_W	207_Q	0.573	0.88
246_S	462_H	0.573	0.88
248_Q	252_M	0.572	0.88
325_F	347_T	0.572	0.88
79_W	135_A	0.572	0.88
406_K	409_G	0.572	0.88
294_Q	517_L	0.571	0.88
28_S	38_S	0.570	0.88
275_L	279_N	0.568	0.88
476_G	480_D	0.568	0.88
447_F	451_N	0.567	0.88
51_L	59_P	0.566	0.88
459_F	489_I	0.566	0.88
178_P	183_L	0.564	0.88
34_I	38_S	0.564	0.88
200_T	205_Y	0.561	0.87
157_F	163_L	0.561	0.87
55_L	61_F	0.561	0.87
21_L	28_S	0.560	0.87
435_Y	438_H	0.560	0.87
200_T	207_Q	0.560	0.87
211_S	216_L	0.558	0.87
20_A	33_A	0.557	0.87
146_Y	152_R	0.557	0.87
480_D	483_T	0.556	0.87
220_N	224_P	0.556	0.87
328_T	331_Q	0.555	0.87
21_L	27_F	0.555	0.87
64_P	68_K	0.554	0.87
246_S	461_D	0.554	0.87
24_F	36_Y	0.553	0.87
84_A	96_F	0.552	0.86
245_E	389_L	0.552	0.86
225_L	228_F	0.552	0.86
166_H	169_A	0.549	0.86
329_N	368_V	0.549	0.86
76_V	79_W	0.549	0.86
128_A	131_Y	0.547	0.86
52_F	57_L	0.547	0.86
238_T	382_K	0.546	0.86
25_W	38_S	0.546	0.86
42_G	49_S	0.545	0.86
245_E	392_T	0.544	0.86
363_E	367_N	0.544	0.86
176_N	179_F	0.542	0.85
520_L	524_W	0.542	0.85
172_T	177_K	0.541	0.85
261_T	266_D	0.540	0.85
123_K	133_A	0.540	0.85
179_F	183_L	0.540	0.85
225_L	229_K	0.540	0.85
342_V	346_Q	0.539	0.85
171_N	178_P	0.539	0.85
364_Y	367_N	0.539	0.85
519_E	538_T	0.539	0.85
251_R	254_L	0.537	0.85
219_N	225_L	0.536	0.85
53_S	61_F	0.534	0.85
314_M	384_L	0.534	0.85
19_W	30_L	0.533	0.84
269_H	492_L	0.532	0.84
205_Y	209_L	0.531	0.84
109_T	112_A	0.531	0.84
22_L	29_T	0.531	0.84
353_M	356_Q	0.530	0.84
436_N	517_L	0.529	0.84
181_K	184_D	0.529	0.84
244_G	392_T	0.529	0.84
236_P	382_K	0.528	0.84
153_Y	157_F	0.528	0.84
368_V	439_V	0.527	0.84
261_T	265_L	0.526	0.84
171_N	175_K	0.526	0.84
64_P	67_I	0.525	0.84
52_F	60_V	0.525	0.84
152_R	156_S	0.524	0.83
63_F	67_I	0.524	0.83
313_L	521_I	0.523	0.83
465_E	468_D	0.523	0.83
268_L	441_A	0.522	0.83
42_G	48_D	0.522	0.83
260_E	434_L	0.522	0.83
192_P	199_L	0.521	0.83
246_S	393_H	0.520	0.83
424_E	428_D	0.520	0.83
193_A	199_L	0.520	0.83
493_L	523_T	0.520	0.83
201_G	208_Q	0.519	0.83
89_Y	92_Y	0.518	0.83
233_G	236_P	0.517	0.83
146_Y	151_W	0.516	0.83
329_N	363_E	0.516	0.83
165_L	169_A	0.515	0.82
436_N	440_V	0.513	0.82
83_L	128_A	0.513	0.82
72_A	75_G	0.513	0.82
453_N	457_V	0.510	0.82
328_T	332_T	0.510	0.82
441_A	444_I	0.509	0.82
154_V	161_Y	0.509	0.82
194_A	204_Q	0.508	0.82
144_P	147_I	0.506	0.81
170_M	175_K	0.506	0.81
88_Y	92_Y	0.504	0.81
349_K	352_Y	0.504	0.81
28_S	39_G	0.504	0.81
239_L	313_L	0.503	0.81
188_S	197_Q	0.501	0.81
293_Q	297_T	0.501	0.81
479_E	486_M	0.501	0.81
148_P	152_R	0.500	0.81
172_T	175_K	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w5qA	1	0.6049	100	0.514	Contact Map
4uorA	3	0.5893	100	0.515	Contact Map
2w8dA	1	0.6049	100	0.519	Contact Map
3lxqA	1	0.5719	100	0.523	Contact Map
4tn0A	1	0.5199	100	0.538	Contact Map
4kavA	1	0.5598	100	0.539	Contact Map
4upkA	3	0.5633	100	0.542	Contact Map
4uplA	2	0.5685	100	0.542	Contact Map
4uopA	2	0.5945	100	0.542	Contact Map
3b5qA	1	0.5598	100	0.545	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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