GREMLIN Database
IBPB - Small heat shock protein IbpB
UniProt: P0C058 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11535
Length: 142 (134)
Sequences: 1130 (586)
Seq/√Len: 50.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_R118_D4.1741.00
60_E131_R4.1281.00
70_V117_I3.6871.00
46_R116_H3.1381.00
104_E122_N3.0841.00
48_T114_L2.6641.00
41_D44_H2.6351.00
71_K94_S2.5071.00
51_L110_F2.4811.00
52_A91_Q2.3591.00
51_L59_L2.2771.00
106_S120_I2.2531.00
56_Q59_L2.2491.00
62_Q69_S2.2011.00
32_F91_Q2.1761.00
61_I70_V2.0721.00
102_N127_I1.8970.99
40_S44_H1.8710.99
58_D74_P1.8550.99
46_R121_R1.8370.99
106_S109_T1.7280.99
38_E81_K1.6990.99
39_K92_P1.6960.99
39_K82_K1.6680.98
55_R112_N1.6440.98
55_R58_D1.6380.98
49_L70_V1.5990.98
4_F28_E1.5790.98
10_M74_P1.5460.97
48_T116_H1.4840.96
8_P11_R1.4560.96
23_L26_A1.4430.96
22_A26_A1.3780.95
109_T135_S1.3720.95
49_L130_Q1.3590.94
10_M20_A1.3510.94
58_D75_E1.3490.94
60_E73_T1.3000.93
20_A23_L1.2750.92
56_Q109_T1.2140.90
81_K85_H1.1950.89
18_K45_Y1.1660.88
105_V119_L1.1610.88
24_Q35_Y1.1470.87
59_L110_F1.1460.87
110_F114_L1.1060.85
61_I105_V1.0840.84
13_W100_A1.0790.84
58_D73_T1.0770.84
43_N70_V1.0750.84
65_G127_I1.0320.81
75_E79_E1.0160.80
32_F38_E1.0070.79
9_L26_A1.0060.79
58_D80_E1.0060.79
6_L20_A0.9920.78
60_E71_K0.9830.78
94_S98_T0.9830.78
38_E48_T0.9650.76
15_G91_Q0.9570.76
13_W20_A0.9530.75
14_I39_K0.9500.75
10_M35_Y0.9400.74
7_S131_R0.9360.74
34_P52_A0.9260.73
69_S85_H0.9250.73
48_T88_L0.9250.73
39_K90_N0.9250.73
56_Q136_E0.9230.73
110_F116_H0.9220.73
16_F100_A0.9190.73
126_P129_A0.9090.72
36_N116_H0.8980.71
24_Q67_R0.8930.70
107_G135_S0.8890.70
32_F95_L0.8890.70
30_Q82_K0.8790.69
86_Q90_N0.8790.69
32_F63_L0.8750.69
39_K63_L0.8740.69
38_E54_F0.8690.68
69_S137_R0.8560.67
5_D20_A0.8550.67
129_A132_I0.8550.67
20_A74_P0.8540.67
127_I131_R0.8530.67
31_S43_N0.8490.67
78_K118_D0.8370.65
64_E136_E0.8320.65
13_W18_K0.8250.64
4_F90_N0.8240.64
31_S107_G0.8110.63
30_Q36_N0.8090.63
39_K96_S0.8060.63
106_S122_N0.7900.61
57_E60_E0.7850.60
117_I131_R0.7780.60
133_A136_E0.7740.59
32_F52_A0.7720.59
56_Q133_A0.7710.59
62_Q98_T0.7710.59
59_L62_Q0.7680.59
5_D12_Q0.7640.58
61_I79_E0.7630.58
4_F10_M0.7600.58
72_G125_E0.7580.58
97_F108_A0.7550.57
36_N86_Q0.7500.57
60_E116_H0.7490.57
111_V116_H0.7450.56
45_Y94_S0.7450.56
10_M22_A0.7410.56
122_N128_A0.7360.56
84_L100_A0.7320.55
107_G118_D0.7300.55
17_D135_S0.7290.55
71_K104_E0.7280.55
78_K81_K0.7270.55
42_D45_Y0.7260.55
13_W67_R0.7250.54
47_I103_M0.7220.54
79_E133_A0.7160.54
31_S71_K0.7140.53
34_P91_Q0.6980.52
35_Y85_H0.6960.51
103_M122_N0.6930.51
63_L95_L0.6890.51
52_A89_M0.6870.51
42_D79_E0.6860.50
24_Q30_Q0.6840.50
44_H107_G0.6810.50
11_R14_I0.6790.50
65_G88_L0.6730.49
4_F21_N0.6670.48
18_K103_M0.6640.48
47_I99_L0.6600.48
71_K77_P0.6560.47
63_L80_E0.6560.47
71_K131_R0.6520.47
50_A91_Q0.6490.47
64_E85_H0.6490.47
12_Q19_L0.6480.46
32_F36_N0.6480.46
63_L69_S0.6480.46
10_M50_A0.6460.46
66_T98_T0.6420.46
16_F37_I0.6380.45
13_W27_G0.6380.45
39_K61_I0.6350.45
96_S100_A0.6330.45
76_Q80_E0.6310.45
59_L95_L0.6300.45
79_E109_T0.6170.43
104_E120_I0.6160.43
66_T101_E0.6160.43
64_E110_F0.6140.43
5_D19_L0.6140.43
61_I112_N0.6120.43
75_E120_I0.6100.43
20_A62_Q0.6090.43
109_T117_I0.6080.42
9_L102_N0.6080.42
24_Q88_L0.6060.42
86_Q100_A0.6050.42
69_S98_T0.6040.42
60_E133_A0.6040.42
70_V105_V0.6020.42
51_L89_M0.6000.42
49_L76_Q0.5870.40
49_L63_L0.5870.40
61_I69_S0.5850.40
28_E71_K0.5850.40
27_G60_E0.5830.40
10_M103_M0.5800.40
44_H80_E0.5790.40
19_L72_G0.5660.38
25_N95_L0.5630.38
84_L114_L0.5620.38
76_Q111_V0.5610.38
4_F27_G0.5590.38
59_L89_M0.5580.37
13_W39_K0.5560.37
9_L45_Y0.5550.37
14_I47_I0.5440.36
25_N137_R0.5440.36
73_T86_Q0.5390.36
109_T118_D0.5320.35
16_F89_M0.5310.35
108_A132_I0.5280.35
78_K137_R0.5280.35
44_H86_Q0.5280.35
82_K86_Q0.5170.34
15_G119_L0.5110.33
54_F72_G0.5080.33
9_L20_A0.5080.33
130_Q133_A0.5050.33
15_G50_A0.5040.32
11_R17_D0.5040.32
29_S110_F0.5040.32
44_H125_E0.5000.32
34_P61_I0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3w1zA 7 0.9155 99.8 0.647 Contact Map
2klrA 2 0.5563 99.8 0.648 Contact Map
2bolA 2 0.9366 99.8 0.65 Contact Map
1gmeA 6 0.9437 99.8 0.665 Contact Map
3aabA 2 0.7817 99.8 0.674 Contact Map
4eldA 4 0.7465 99.8 0.676 Contact Map
4ydzA 4 0.838 99.7 0.686 Contact Map
4jutA 4 0.6127 99.7 0.702 Contact Map
4ye0A 2 0.6831 99.7 0.705 Contact Map
3l1eA 2 0.6972 99.6 0.707 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.