TRKA - ECOLI - GREMLIN Contacts

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TRKA - Trk system potassium uptake protein TrkA

UniProt:	P0AGI8	Sequences: MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSPDYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKAYYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQNTIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERLFQPSPFFL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11019
Length:	458 (442)
Sequences:	1498 (1034)
Seq/√Len:	49.2

ECOLI - TRKA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
282_G	289_L	6.504	1.00
252_E	277_T	5.941	1.00
236_M	298_V	5.801	1.00
6_L	52_G	5.185	1.00
315_A	328_V	5.148	1.00
160_A	203_V	5.089	1.00
240_G	270_L	4.958	1.00
264_Q	281_F	4.764	1.00
385_A	428_I	4.559	1.00
59_R	64_D	3.983	1.00
238_V	301_F	3.713	1.00
2_K	25_D	3.702	1.00
259_L	277_T	3.666	1.00
36_L	47_V	3.656	1.00
168_G	204_E	3.613	1.00
238_V	284_A	3.513	1.00
400_D	425_N	3.487	1.00
167_I	205_A	3.404	1.00
16_A	43_F	3.327	1.00
153_V	412_A	3.290	1.00
171_L	185_V	3.276	1.00
398_V	401_E	3.194	1.00
188_I	201_T	3.063	1.00
88_S	116_A	2.996	1.00
199_G	424_D	2.953	1.00
160_A	167_I	2.871	1.00
170_A	173_T	2.849	1.00
137_I	300_L	2.815	1.00
4_I	63_A	2.787	1.00
162_Y	205_A	2.786	1.00
248_A	259_L	2.778	1.00
248_A	274_L	2.701	1.00
188_I	203_V	2.665	1.00
30_D	36_L	2.574	1.00
396_G	429_E	2.521	1.00
190_R	207_D	2.514	1.00
129_V	348_I	2.439	1.00
266_R	269_E	2.329	1.00
390_S	430_Q	2.321	1.00
63_A	92_T	2.315	1.00
80_M	119_I	2.197	1.00
261_E	267_A	2.182	1.00
5_I	16_A	2.130	1.00
172_S	200_S	2.114	1.00
319_K	345_D	2.050	1.00
147_N	151_G	2.014	1.00
413_V	426_L	2.001	1.00
400_D	424_D	1.992	0.99
170_A	202_I	1.982	0.99
290_L	295_I	1.930	0.99
196_R	199_G	1.887	0.99
152_K	417_N	1.875	0.99
69_L	82_A	1.871	0.99
20_V	45_L	1.868	0.99
87_Y	95_R	1.848	0.99
160_A	164_G	1.843	0.99
13_G	43_F	1.838	0.99
83_C	95_R	1.810	0.99
236_M	293_E	1.786	0.99
295_I	323_A	1.762	0.99
415_R	432_D	1.753	0.99
399_I	410_I	1.750	0.99
167_I	203_V	1.746	0.99
168_G	205_A	1.723	0.99
301_F	318_A	1.674	0.98
33_G	49_Q	1.673	0.98
4_I	66_A	1.664	0.98
29_V	57_V	1.612	0.98
415_R	420_M	1.602	0.98
62_G	65_D	1.601	0.98
396_G	427_R	1.596	0.98
84_Q	88_S	1.584	0.97
410_I	436_M	1.583	0.97
289_L	293_E	1.580	0.97
169_N	173_T	1.576	0.97
32_N	35_R	1.562	0.97
245_A	266_R	1.562	0.97
404_L	408_T	1.554	0.97
363_R	379_E	1.553	0.97
237_L	248_A	1.544	0.97
134_Y	250_R	1.541	0.97
260_I	289_L	1.532	0.97
5_I	15_L	1.514	0.97
236_M	301_F	1.513	0.97
252_E	275_Q	1.510	0.97
258_K	293_E	1.510	0.97
385_A	395_V	1.509	0.97
83_C	97_A	1.506	0.96
152_K	251_L	1.504	0.96
158_V	211_F	1.502	0.96
370_V	381_I	1.489	0.96
137_I	302_I	1.470	0.96
235_I	300_L	1.456	0.96
280_F	289_L	1.447	0.96
13_G	39_L	1.443	0.95
69_L	92_T	1.440	0.95
39_L	43_F	1.439	0.95
264_Q	268_A	1.416	0.95
186_A	411_G	1.408	0.95
36_L	89_L	1.406	0.95
241_G	283_D	1.405	0.95
32_N	327_M	1.398	0.95
151_G	283_D	1.367	0.94
84_Q	118_P	1.366	0.94
85_V	111_L	1.357	0.94
304_V	329_L	1.353	0.94
241_G	244_G	1.350	0.94
244_G	248_A	1.349	0.94
235_I	254_D	1.333	0.93
56_R	60_E	1.328	0.93
9_G	12_G	1.325	0.93
220_A	271_A	1.323	0.93
241_G	332_R	1.321	0.93
184_R	409_I	1.320	0.93
9_G	98_R	1.306	0.92
128_L	353_A	1.306	0.92
423_N	426_L	1.293	0.92
398_V	427_R	1.286	0.92
245_A	249_R	1.272	0.91
28_V	45_L	1.272	0.91
39_L	45_L	1.260	0.91
367_I	381_I	1.260	0.91
413_V	422_A	1.251	0.91
69_L	86_A	1.245	0.90
27_T	46_R	1.241	0.90
235_I	255_Y	1.228	0.90
83_C	123_I	1.216	0.89
288_E	291_A	1.212	0.89
76_D	308_D	1.210	0.89
15_L	72_V	1.207	0.89
378_A	437_F	1.202	0.89
157_V	210_F	1.199	0.89
7_G	12_G	1.195	0.89
51_H	77_E	1.190	0.88
366_D	386_H	1.190	0.88
16_A	28_V	1.190	0.88
197_P	424_D	1.187	0.88
89_L	92_T	1.185	0.88
10_Q	329_L	1.180	0.88
99_I	292_E	1.177	0.88
235_I	302_I	1.176	0.88
87_Y	118_P	1.175	0.88
187_A	194_P	1.168	0.87
188_I	195_I	1.154	0.87
420_M	426_L	1.152	0.87
245_A	269_E	1.151	0.87
29_V	48_V	1.147	0.86
244_G	304_V	1.144	0.86
269_E	273_K	1.143	0.86
274_L	277_T	1.133	0.86
309_E	335_Y	1.133	0.86
405_P	437_F	1.110	0.85
3_I	26_I	1.108	0.84
2_K	65_D	1.105	0.84
265_Q	268_A	1.104	0.84
252_E	276_N	1.100	0.84
240_G	261_E	1.092	0.84
11_V	98_R	1.077	0.83
167_I	204_E	1.073	0.82
154_S	215_S	1.065	0.82
33_G	37_R	1.063	0.82
103_D	119_I	1.061	0.82
313_M	437_F	1.061	0.82
410_I	413_V	1.059	0.82
3_I	42_K	1.058	0.82
5_I	26_I	1.055	0.81
328_V	344_I	1.049	0.81
129_V	329_L	1.046	0.81
236_M	260_I	1.041	0.80
37_R	41_D	1.038	0.80
248_A	277_T	1.036	0.80
169_N	174_M	1.025	0.79
259_L	274_L	1.016	0.79
286_D	319_K	1.016	0.79
134_Y	247_L	1.012	0.79
168_G	337_D	1.007	0.78
131_D	250_R	1.006	0.78
203_V	225_L	1.005	0.78
291_A	321_M	1.005	0.78
247_L	339_V	1.004	0.78
184_R	424_D	1.003	0.78
54_H	103_D	1.000	0.78
213_A	217_H	0.996	0.77
6_L	82_A	0.988	0.77
10_Q	80_M	0.987	0.77
257_V	277_T	0.984	0.77
395_V	430_Q	0.982	0.76
81_V	84_Q	0.978	0.76
30_D	47_V	0.973	0.76
245_A	270_L	0.971	0.76
283_D	332_R	0.968	0.75
185_V	217_H	0.967	0.75
157_V	340_Q	0.961	0.75
313_M	340_Q	0.960	0.75
186_A	212_I	0.955	0.74
61_A	66_A	0.952	0.74
38_T	41_D	0.951	0.74
157_V	208_E	0.949	0.74
160_A	224_E	0.945	0.74
148_F	380_A	0.944	0.74
173_T	176_E	0.944	0.74
245_A	273_K	0.943	0.73
10_Q	14_T	0.939	0.73
268_A	272_E	0.937	0.73
142_A	145_V	0.936	0.73
309_E	312_I	0.932	0.73
348_I	353_A	0.929	0.72
10_Q	306_N	0.925	0.72
34_E	262_R	0.924	0.72
95_R	146_V	0.923	0.72
8_A	39_L	0.922	0.72
384_V	433_H	0.918	0.71
188_I	197_P	0.917	0.71
237_L	313_M	0.915	0.71
184_R	422_A	0.915	0.71
397_R	401_E	0.906	0.70
251_L	257_V	0.906	0.70
409_I	424_D	0.905	0.70
59_R	348_I	0.905	0.70
80_M	84_Q	0.903	0.70
237_L	355_I	0.899	0.70
66_A	92_T	0.899	0.70
381_I	436_M	0.896	0.70
40_Q	47_V	0.891	0.69
410_I	422_A	0.889	0.69
10_Q	331_Q	0.887	0.69
415_R	426_L	0.886	0.69
214_A	348_I	0.886	0.69
14_T	18_N	0.885	0.69
197_P	409_I	0.882	0.68
301_F	314_S	0.877	0.68
422_A	426_L	0.873	0.68
22_E	363_R	0.872	0.67
168_G	171_L	0.872	0.67
42_K	48_V	0.866	0.67
121_H	124_A	0.865	0.67
54_H	101_S	0.863	0.67
259_L	340_Q	0.862	0.67
26_I	39_L	0.857	0.66
241_G	399_I	0.855	0.66
415_R	429_E	0.853	0.66
234_R	256_S	0.852	0.66
265_Q	269_E	0.852	0.66
295_I	448_E	0.851	0.66
187_A	378_A	0.849	0.65
162_Y	206_G	0.848	0.65
245_A	315_A	0.848	0.65
28_V	31_T	0.847	0.65
50_G	57_V	0.847	0.65
133_I	302_I	0.845	0.65
164_G	167_I	0.842	0.65
2_K	131_D	0.838	0.64
188_I	336_V	0.837	0.64
100_R	126_E	0.836	0.64
174_M	203_V	0.835	0.64
4_I	27_T	0.832	0.64
408_T	420_M	0.832	0.64
339_V	357_A	0.831	0.64
348_I	368_V	0.830	0.64
85_V	413_V	0.830	0.64
196_R	424_D	0.829	0.64
414_V	419_V	0.829	0.64
117_V	411_G	0.828	0.63
273_K	431_G	0.828	0.63
40_Q	422_A	0.826	0.63
409_I	422_A	0.825	0.63
308_D	350_P	0.824	0.63
14_T	308_D	0.824	0.63
4_I	292_E	0.823	0.63
213_A	218_I	0.820	0.63
26_I	211_F	0.818	0.62
273_K	279_V	0.817	0.62
287_Q	330_I	0.817	0.62
349_S	421_I	0.813	0.62
119_I	122_L	0.811	0.62
285_S	310_A	0.809	0.62
161_Y	164_G	0.807	0.61
223_S	228_L	0.806	0.61
241_G	284_A	0.805	0.61
235_I	253_K	0.802	0.61
169_N	177_H	0.802	0.61
336_V	340_Q	0.802	0.61
301_F	436_M	0.798	0.61
245_A	274_L	0.797	0.60
46_R	199_G	0.797	0.60
94_N	120_D	0.795	0.60
15_L	109_D	0.793	0.60
192_D	211_F	0.793	0.60
267_A	281_F	0.793	0.60
249_R	401_E	0.787	0.59
185_V	221_V	0.786	0.59
80_M	118_P	0.786	0.59
213_A	221_V	0.786	0.59
11_V	354_T	0.781	0.59
206_G	401_E	0.779	0.59
327_M	348_I	0.777	0.58
428_I	447_V	0.776	0.58
276_N	404_L	0.772	0.58
127_Q	131_D	0.772	0.58
82_A	188_I	0.771	0.58
149_A	414_V	0.771	0.58
72_V	123_I	0.769	0.58
203_V	397_R	0.768	0.58
291_A	296_D	0.765	0.57
30_D	382_E	0.765	0.57
99_I	118_P	0.765	0.57
173_T	256_S	0.763	0.57
179_P	279_V	0.762	0.57
13_G	38_T	0.762	0.57
216_Q	418_D	0.761	0.57
76_D	359_L	0.760	0.57
167_I	200_S	0.760	0.57
57_V	327_M	0.759	0.57
153_V	435_I	0.758	0.57
294_H	298_V	0.756	0.56
25_D	425_N	0.754	0.56
347_A	408_T	0.753	0.56
295_I	397_R	0.753	0.56
70_V	362_V	0.750	0.56
366_D	431_G	0.748	0.56
411_G	437_F	0.746	0.55
232_Y	300_L	0.743	0.55
132_N	196_R	0.742	0.55
64_D	165_P	0.741	0.55
133_I	247_L	0.741	0.55
82_A	210_F	0.740	0.55
395_V	431_G	0.740	0.55
330_I	374_R	0.739	0.55
314_S	344_I	0.739	0.55
80_M	440_D	0.733	0.54
303_A	315_A	0.732	0.54
270_L	316_M	0.732	0.54
235_I	251_L	0.731	0.54
124_A	329_L	0.730	0.54
174_M	217_H	0.727	0.53
368_V	384_V	0.727	0.53
182_D	217_H	0.727	0.53
362_V	434_V	0.726	0.53
153_V	414_V	0.726	0.53
385_A	431_G	0.724	0.53
100_R	363_R	0.721	0.53
249_R	273_K	0.720	0.53
93_P	396_G	0.719	0.53
149_A	153_V	0.715	0.52
53_S	77_E	0.715	0.52
107_D	185_V	0.713	0.52
263_N	354_T	0.710	0.52
200_S	263_N	0.710	0.52
56_R	103_D	0.710	0.52
59_R	107_D	0.708	0.52
63_A	323_A	0.707	0.51
313_M	351_Q	0.706	0.51
123_I	305_T	0.706	0.51
92_T	323_A	0.706	0.51
256_S	416_G	0.705	0.51
394_V	447_V	0.705	0.51
58_L	303_A	0.704	0.51
60_E	413_V	0.704	0.51
273_K	401_E	0.703	0.51
196_R	304_V	0.700	0.51
199_G	283_D	0.700	0.51
282_G	290_L	0.700	0.51
180_H	373_L	0.700	0.51
29_V	249_R	0.698	0.51
171_L	197_P	0.698	0.51
27_T	330_I	0.697	0.50
170_A	177_H	0.697	0.50
279_V	413_V	0.696	0.50
129_V	351_Q	0.695	0.50
263_N	344_I	0.694	0.50
394_V	428_I	0.694	0.50
128_L	357_A	0.689	0.50
2_K	24_N	0.684	0.49
214_A	217_H	0.684	0.49
244_G	259_L	0.682	0.49
206_G	447_V	0.681	0.49
45_L	73_T	0.679	0.49
56_R	235_I	0.678	0.49
185_V	347_A	0.678	0.49
381_I	438_L	0.677	0.48
342_S	433_H	0.677	0.48
24_N	308_D	0.677	0.48
4_I	62_G	0.676	0.48
216_Q	392_S	0.675	0.48
285_S	332_R	0.675	0.48
262_R	281_F	0.675	0.48
163_G	167_I	0.674	0.48
29_V	247_L	0.673	0.48
328_V	429_E	0.673	0.48
57_V	61_A	0.672	0.48
123_I	354_T	0.671	0.48
287_Q	291_A	0.670	0.48
332_R	349_S	0.668	0.47
248_A	312_I	0.667	0.47
81_V	146_V	0.667	0.47
173_T	253_K	0.666	0.47
6_L	69_L	0.666	0.47
2_K	309_E	0.666	0.47
146_V	213_A	0.665	0.47
253_K	276_N	0.663	0.47
81_V	104_Y	0.662	0.47
304_V	312_I	0.661	0.47
85_V	213_A	0.661	0.47
333_R	351_Q	0.660	0.47
100_R	185_V	0.660	0.47
377_V	417_N	0.660	0.47
51_H	124_A	0.659	0.47
126_E	258_K	0.659	0.47
407_G	437_F	0.658	0.46
66_A	286_D	0.656	0.46
118_P	243_I	0.656	0.46
385_A	430_Q	0.655	0.46
223_S	447_V	0.655	0.46
172_S	243_I	0.653	0.46
28_V	428_I	0.652	0.46
97_A	358_L	0.651	0.46
262_R	306_N	0.650	0.46
261_E	283_D	0.649	0.46
68_M	362_V	0.649	0.46
147_N	154_S	0.647	0.45
8_A	405_P	0.647	0.45
398_V	424_D	0.647	0.45
392_S	451_F	0.644	0.45
365_A	448_E	0.640	0.45
199_G	409_I	0.639	0.45
29_V	406_P	0.633	0.44
103_D	410_I	0.632	0.44
36_L	45_L	0.629	0.44
52_G	124_A	0.628	0.43
136_L	244_G	0.628	0.43
219_R	423_N	0.627	0.43
36_L	351_Q	0.626	0.43
233_K	416_G	0.626	0.43
77_E	81_V	0.626	0.43
71_A	379_E	0.626	0.43
159_K	208_E	0.625	0.43
20_V	104_Y	0.625	0.43
267_A	293_E	0.624	0.43
259_L	361_H	0.624	0.43
4_I	269_E	0.624	0.43
17_E	288_E	0.623	0.43
301_F	323_A	0.622	0.43
103_D	143_L	0.621	0.43
213_A	250_R	0.621	0.43
2_K	62_G	0.620	0.43
348_I	351_Q	0.620	0.43
330_I	425_N	0.620	0.43
151_G	261_E	0.618	0.42
162_Y	214_A	0.618	0.42
199_G	428_I	0.618	0.42
72_V	394_V	0.618	0.42
195_I	437_F	0.616	0.42
287_Q	328_V	0.614	0.42
10_Q	100_R	0.613	0.42
144_Q	213_A	0.613	0.42
139_Y	211_F	0.613	0.42
259_L	368_V	0.612	0.42
64_D	281_F	0.610	0.42
284_A	412_A	0.610	0.42
33_G	64_D	0.610	0.42
218_I	349_S	0.609	0.42
53_S	308_D	0.608	0.41
240_G	245_A	0.607	0.41
343_V	391_T	0.607	0.41
146_V	422_A	0.606	0.41
166_L	251_L	0.606	0.41
54_H	107_D	0.606	0.41
49_Q	165_P	0.606	0.41
51_H	54_H	0.605	0.41
284_A	310_A	0.604	0.41
287_Q	332_R	0.604	0.41
105_V	140_P	0.603	0.41
303_A	318_A	0.603	0.41
49_Q	160_A	0.602	0.41
285_S	316_M	0.601	0.41
2_K	395_V	0.601	0.41
263_N	446_D	0.601	0.41
91_N	355_I	0.601	0.41
185_V	361_H	0.599	0.41
353_A	357_A	0.599	0.41
386_H	391_T	0.598	0.40
84_Q	354_T	0.597	0.40
83_C	382_E	0.596	0.40
33_G	281_F	0.595	0.40
145_V	349_S	0.594	0.40
125_P	282_G	0.592	0.40
69_L	230_K	0.590	0.40
212_I	421_I	0.590	0.40
116_A	119_I	0.589	0.40
156_A	218_I	0.589	0.40
14_T	328_V	0.588	0.40
36_L	40_Q	0.587	0.39
153_V	250_R	0.586	0.39
196_R	430_Q	0.586	0.39
75_S	104_Y	0.586	0.39
181_I	217_H	0.585	0.39
160_A	354_T	0.582	0.39
299_D	324_K	0.582	0.39
28_V	138_E	0.581	0.39
194_P	377_V	0.581	0.39
68_M	229_E	0.580	0.39
283_D	426_L	0.580	0.39
39_L	415_R	0.580	0.39
278_I	293_E	0.580	0.39
137_I	327_M	0.580	0.39
80_M	100_R	0.579	0.39
399_I	402_I	0.579	0.39
88_S	118_P	0.578	0.39
63_A	91_N	0.578	0.39
195_I	228_L	0.577	0.38
313_M	335_Y	0.576	0.38
80_M	229_E	0.575	0.38
80_M	258_K	0.575	0.38
9_G	45_L	0.575	0.38
42_K	401_E	0.572	0.38
16_A	55_P	0.571	0.38
145_V	303_A	0.571	0.38
84_Q	122_L	0.571	0.38
75_S	195_I	0.571	0.38
330_I	340_Q	0.570	0.38
237_L	260_I	0.569	0.38
30_D	148_F	0.569	0.38
241_G	282_G	0.569	0.38
402_I	428_I	0.569	0.38
192_D	396_G	0.569	0.38
304_V	315_A	0.569	0.38
160_A	221_V	0.568	0.38
123_I	448_E	0.568	0.38
88_S	243_I	0.568	0.38
287_Q	360_S	0.567	0.37
307_D	310_A	0.567	0.37
153_V	419_V	0.567	0.37
27_T	206_G	0.566	0.37
378_A	382_E	0.566	0.37
54_H	89_L	0.565	0.37
237_L	302_I	0.564	0.37
330_I	359_L	0.564	0.37
180_H	192_D	0.564	0.37
345_D	451_F	0.563	0.37
264_Q	267_A	0.563	0.37
55_P	89_L	0.562	0.37
212_I	265_Q	0.562	0.37
1_M	7_G	0.562	0.37
208_E	312_I	0.562	0.37
190_R	195_I	0.561	0.37
120_D	248_A	0.561	0.37
24_N	350_P	0.561	0.37
131_D	236_M	0.561	0.37
131_D	134_Y	0.560	0.37
45_L	52_G	0.560	0.37
192_D	320_R	0.560	0.37
156_A	279_V	0.560	0.37
206_G	223_S	0.559	0.37
243_I	335_Y	0.559	0.37
36_L	236_M	0.558	0.37
204_E	220_A	0.557	0.37
241_G	266_R	0.557	0.37
320_R	341_G	0.556	0.36
376_G	451_F	0.556	0.36
70_V	357_A	0.556	0.36
412_A	435_I	0.555	0.36
361_H	367_I	0.555	0.36
128_L	312_I	0.555	0.36
394_V	401_E	0.554	0.36
39_L	123_I	0.553	0.36
69_L	95_R	0.553	0.36
173_T	177_H	0.553	0.36
153_V	350_P	0.553	0.36
17_E	31_T	0.552	0.36
394_V	442_K	0.551	0.36
84_Q	87_Y	0.550	0.36
268_A	338_L	0.550	0.36
76_D	100_R	0.549	0.36
301_F	339_V	0.549	0.36
24_N	345_D	0.548	0.36
78_T	92_T	0.547	0.36
100_R	125_P	0.546	0.36
28_V	39_L	0.545	0.35
187_A	429_E	0.545	0.35
75_S	99_I	0.545	0.35
210_F	437_F	0.544	0.35
161_Y	227_R	0.544	0.35
314_S	370_V	0.543	0.35
228_L	280_F	0.542	0.35
187_A	316_M	0.541	0.35
109_D	114_S	0.539	0.35
284_A	325_K	0.539	0.35
283_D	333_R	0.538	0.35
184_R	199_G	0.538	0.35
286_D	327_M	0.538	0.35
157_V	409_I	0.538	0.35
434_V	443_F	0.537	0.35
6_L	285_S	0.537	0.35
129_V	323_A	0.536	0.35
221_V	286_D	0.536	0.35
39_L	253_K	0.534	0.34
155_L	414_V	0.534	0.34
50_G	308_D	0.534	0.34
4_I	58_L	0.534	0.34
80_M	256_S	0.533	0.34
232_Y	325_K	0.533	0.34
18_N	351_Q	0.533	0.34
394_V	402_I	0.531	0.34
245_A	267_A	0.531	0.34
17_E	337_D	0.530	0.34
302_I	343_V	0.529	0.34
150_E	416_G	0.528	0.34
236_M	294_H	0.528	0.34
180_H	399_I	0.528	0.34
63_A	89_L	0.527	0.34
355_I	383_A	0.527	0.34
109_D	273_K	0.526	0.34
133_I	348_I	0.526	0.34
95_R	364_K	0.525	0.34
267_A	289_L	0.525	0.34
214_A	330_I	0.525	0.34
111_L	428_I	0.525	0.34
111_L	118_P	0.525	0.34
65_D	276_N	0.524	0.33
81_V	119_I	0.523	0.33
274_L	280_F	0.522	0.33
70_V	78_T	0.521	0.33
238_V	314_S	0.520	0.33
249_R	392_S	0.520	0.33
121_H	361_H	0.520	0.33
274_L	306_N	0.520	0.33
133_I	363_R	0.519	0.33
263_N	442_K	0.518	0.33
162_Y	429_E	0.518	0.33
42_K	416_G	0.518	0.33
142_A	221_V	0.517	0.33
307_D	359_L	0.516	0.33
32_N	295_I	0.516	0.33
176_E	410_I	0.515	0.33
28_V	392_S	0.515	0.33
8_A	12_G	0.515	0.33
380_A	437_F	0.515	0.33
16_A	344_I	0.514	0.33
186_A	437_F	0.514	0.33
348_I	427_R	0.511	0.32
415_R	435_I	0.511	0.32
34_E	37_R	0.510	0.32
204_E	330_I	0.509	0.32
132_N	300_L	0.508	0.32
187_A	225_L	0.508	0.32
122_L	331_Q	0.507	0.32
208_E	374_R	0.506	0.32
228_L	373_L	0.506	0.32
195_I	316_M	0.506	0.32
405_P	411_G	0.505	0.32
385_A	413_V	0.505	0.32
3_I	19_L	0.505	0.32
136_L	145_V	0.505	0.32
33_G	96_I	0.504	0.32
320_R	357_A	0.504	0.32
128_L	347_A	0.504	0.32
38_T	430_Q	0.504	0.32
383_A	436_M	0.504	0.32
169_N	202_I	0.503	0.32
303_A	407_G	0.503	0.32
115_D	255_Y	0.502	0.32
326_V	344_I	0.501	0.31
262_R	348_I	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g65A	2	0.9934	100	0.429	Contact Map
4gx0A	3	0.9323	100	0.477	Contact Map
3mt5A	5	0.9432	100	0.534	Contact Map
4hpfA	3	0.9258	100	0.535	Contact Map
3nafA	3	0.9585	100	0.536	Contact Map
2aefA	2	0.4782	100	0.734	Contact Map
3l4bC	2	0.4716	100	0.737	Contact Map
1lnqA	6	0.4716	100	0.743	Contact Map
4j91A	3	0.4651	100	0.777	Contact Map
1vctA	3	0.4127	99.9	0.84	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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