GREMLIN Database
RBSC - Ribose transport system permease protein RbsC
UniProt: P0AGI1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10816
Length: 321 (267)
Sequences: 31325 (19569)
Seq/√Len: 1197.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_L229_L3.8631.00
109_A225_S3.5721.00
109_A229_L3.0681.00
86_V107_L2.9641.00
113_A225_S2.9231.00
206_E220_K2.7681.00
90_I103_A2.6881.00
57_A179_M2.5421.00
64_T278_T2.5141.00
199_I223_V2.4771.00
215_N218_K2.4441.00
121_K217_N2.4421.00
218_K222_I2.3441.00
187_W191_H2.3051.00
189_M195_L2.2961.00
108_G232_S2.2691.00
188_Y192_H2.2271.00
112_G228_G2.2201.00
113_A221_I2.2011.00
115_T133_M2.1901.00
198_Y219_I2.1611.00
256_D289_N2.1251.00
195_L222_I2.1181.00
117_V121_K2.1021.00
185_A189_M2.0271.00
96_N99_V1.9861.00
105_L233_L1.9551.00
59_M257_A1.9481.00
81_A141_T1.9351.00
87_A104_A1.9161.00
98_L102_A1.8651.00
101_V236_I1.7871.00
87_A236_I1.7801.00
108_G228_G1.7801.00
53_T286_G1.7571.00
60_A278_T1.7511.00
184_L188_Y1.7381.00
202_L219_I1.7261.00
201_A209_T1.6921.00
66_V227_C1.6891.00
116_G221_I1.6731.00
135_L138_R1.6611.00
65_L186_A1.6221.00
194_R198_Y1.5771.00
53_T283_L1.5681.00
68_L200_Y1.5251.00
57_A282_A1.5241.00
91_V100_A1.5201.00
111_I137_L1.4991.00
105_L236_I1.4951.00
82_L111_I1.4781.00
256_D306_K1.4711.00
195_L199_I1.4661.00
121_K221_I1.4531.00
222_I225_S1.4431.00
206_E210_R1.4331.00
207_A210_R1.4271.00
59_M80_L1.4251.00
78_S138_R1.4191.00
264_G277_G1.4151.00
133_M137_L1.4101.00
89_S144_Y1.3971.00
183_F279_L1.3921.00
198_Y214_I1.3671.00
274_R277_G1.3671.00
99_V102_A1.3531.00
80_L238_E1.3461.00
198_Y209_T1.3321.00
69_T223_V1.3311.00
90_I95_V1.3271.00
62_G230_L1.3071.00
58_I234_A1.3001.00
117_V221_I1.2861.00
95_V99_V1.2751.00
209_T214_I1.2711.00
167_G170_L1.2701.00
202_L216_V1.2681.00
90_I93_I1.2671.00
100_A104_A1.2441.00
65_L223_V1.2441.00
58_I237_I1.2421.00
104_A108_G1.2371.00
45_N290_N1.2341.00
264_G281_G1.2311.00
221_I225_S1.2221.00
61_V186_A1.2161.00
76_V231_A1.2131.00
71_G220_K1.2121.00
214_I219_I1.2081.00
163_W166_I1.2011.00
57_A279_L1.1991.00
120_A217_N1.1831.00
63_M261_V1.1751.00
202_L209_T1.1721.00
49_I287_F1.1711.00
102_A106_A1.1691.00
49_I286_G1.1671.00
95_V103_A1.1661.00
63_M257_A1.1641.00
71_G126_A1.1581.00
106_A109_A1.1531.00
191_H200_Y1.1451.00
79_L111_I1.1191.00
225_S229_L1.1171.00
60_A260_A1.1121.00
78_S137_L1.1061.00
92_G96_N1.1031.00
89_S145_T1.0991.00
86_V90_I1.0971.00
187_W192_H1.0951.00
290_N293_N1.0931.00
166_I169_P1.0911.00
182_V230_L1.0911.00
71_G224_Y1.0871.00
53_T282_A1.0791.00
219_I222_I1.0781.00
62_G76_V1.0731.00
228_G232_S1.0721.00
159_D162_G1.0691.00
210_R216_V1.0661.00
169_P173_P1.0661.00
89_S92_G1.0631.00
109_A232_S1.0631.00
118_I129_A1.0591.00
138_R142_M1.0591.00
210_R217_N1.0551.00
183_F230_L1.0511.00
253_Y256_D1.0391.00
60_A261_V1.0381.00
68_L273_G1.0381.00
222_I226_L1.0361.00
87_A240_A1.0361.00
289_N306_K1.0361.00
85_A141_T1.0341.00
110_A113_A1.0291.00
186_A226_L1.0271.00
301_Y304_I1.0231.00
164_F167_G1.0131.00
177_W181_I1.0111.00
134_M138_R1.0071.00
199_I219_I1.0031.00
184_L187_W1.0001.00
115_T129_A0.9961.00
85_A247_P0.9941.00
117_V122_G0.9941.00
303_M306_K0.9921.00
174_T177_W0.9911.00
181_I185_A0.9891.00
260_A282_A0.9871.00
104_A236_I0.9851.00
102_A105_L0.9841.00
226_L230_L0.9791.00
59_M234_A0.9781.00
156_E159_D0.9721.00
64_T261_V0.9691.00
260_A281_G0.9681.00
47_F51_Q0.9631.00
235_G239_V0.9441.00
120_A130_T0.9431.00
82_L86_V0.9431.00
195_L219_I0.9391.00
291_G295_L0.9361.00
67_I261_V0.9361.00
83_T108_G0.9301.00
158_A161_F0.9281.00
276_V280_I0.9231.00
170_L177_W0.9231.00
54_S176_V0.9231.00
77_G254_E0.9201.00
55_V234_A0.9051.00
44_N47_F0.9051.00
52_Q56_N0.9041.00
179_M183_F0.9041.00
78_S134_M0.9031.00
85_A145_T0.9031.00
167_G171_G0.9021.00
83_T104_A0.9001.00
197_R200_Y0.8991.00
68_L191_H0.8981.00
164_F168_R0.8941.00
119_V129_A0.8941.00
227_C231_A0.8941.00
218_K221_I0.8931.00
90_I100_A0.8931.00
118_I122_G0.8921.00
69_T199_I0.8911.00
64_T273_G0.8901.00
143_V301_Y0.8861.00
180_G184_L0.8821.00
123_R206_E0.8811.00
73_D76_V0.8801.00
60_A282_A0.8791.00
57_A183_F0.8701.00
187_W276_V0.8701.00
87_A91_V0.8691.00
292_L305_V0.8681.00
168_R172_V0.8621.00
58_I179_M0.8611.00
79_L231_A0.8601.00
63_M76_V0.8601.00
84_G239_V0.8581.00
80_L253_Y0.8571.00
168_R171_G0.8551.00
89_S93_I0.8541.00
208_A212_S0.8481.00
252_G256_D0.8481.00
61_V182_V0.8471.00
217_N220_K0.8381.00
202_L223_V0.8341.00
61_V278_T0.8331.00
66_V73_D0.8301.00
248_T251_T0.8291.00
99_V103_A0.8281.00
105_L232_S0.8281.00
272_K276_V0.8261.00
216_V220_K0.8251.00
106_A110_A0.8251.00
65_L190_L0.8241.00
114_V118_I0.8211.00
175_P237_I0.8171.00
153_G156_E0.8151.00
46_L291_G0.8141.00
116_G120_A0.8141.00
77_G252_G0.8111.00
65_L226_L0.8101.00
80_L250_G0.8101.00
285_L306_K0.8101.00
312_L316_V0.8071.00
231_A235_G0.8021.00
205_N208_A0.7961.00
86_V89_S0.7921.00
174_T178_I0.7921.00
278_T282_A0.7921.00
274_R278_T0.7911.00
84_G249_A0.7881.00
139_G142_M0.7831.00
113_A117_V0.7821.00
79_L108_G0.7781.00
202_L220_K0.7771.00
176_V180_G0.7761.00
83_T235_G0.7751.00
190_L199_I0.7741.00
59_M76_V0.7681.00
290_N294_L0.7671.00
206_E216_V0.7621.00
88_A245_A0.7611.00
238_E242_L0.7561.00
229_L232_S0.7541.00
110_A114_V0.7511.00
116_G121_K0.7481.00
148_S151_N0.7451.00
217_N221_I0.7451.00
48_N52_Q0.7441.00
158_A162_G0.7411.00
155_T158_A0.7371.00
84_G245_A0.7371.00
149_P152_T0.7361.00
229_L233_L0.7351.00
59_M62_G0.7291.00
198_Y215_N0.7251.00
169_P172_V0.7251.00
165_G168_R0.7241.00
87_A100_A0.7231.00
185_A188_Y0.7161.00
169_P177_W0.7151.00
136_L140_V0.7141.00
306_K310_I0.7131.00
308_V312_L0.7131.00
58_I182_V0.7111.00
105_L109_A0.7101.00
83_T107_L0.7091.00
80_L234_A0.7081.00
62_G231_A0.7061.00
53_T57_A0.7051.00
282_A286_G0.6981.00
82_L108_G0.6941.00
74_L258_I0.6931.00
283_L287_F0.6921.00
300_Y303_M0.6861.00
56_N256_D0.6801.00
66_V224_Y0.6791.00
56_N260_A0.6741.00
259_A310_I0.6701.00
67_I258_I0.6691.00
126_A224_Y0.6651.00
189_M192_H0.6641.00
101_V105_L0.6601.00
163_W168_R0.6601.00
64_T275_I0.6581.00
299_S302_Q0.6581.00
64_T68_L0.6561.00
45_N294_L0.6541.00
289_N302_Q0.6521.00
49_I53_T0.6461.00
120_A221_I0.6461.00
91_V240_A0.6461.00
49_I290_N0.6451.00
71_G206_E0.6441.00
182_V233_L0.6411.00
216_V219_I0.6401.00
79_L228_G0.6371.00
186_A190_L0.6361.00
79_L83_T0.6351.00
50_L54_S0.6331.00
79_L115_T0.6321.00
188_Y191_H0.6311.00
112_G225_S0.6311.00
82_L137_L0.6301.00
56_N282_A0.6291.00
183_F187_W0.6271.00
232_S236_I0.6171.00
51_Q241_R0.6151.00
173_P177_W0.6141.00
54_S179_M0.6121.00
90_I107_L0.6121.00
108_G112_G0.6121.00
263_L281_G0.6111.00
226_L229_L0.6081.00
109_A112_G0.6031.00
48_N290_N0.6031.00
95_V98_L0.5991.00
69_T202_L0.5951.00
69_T220_K0.5951.00
138_R251_T0.5951.00
119_V224_Y0.5941.00
163_W167_G0.5941.00
83_T231_A0.5921.00
79_L112_G0.5891.00
195_L226_L0.5881.00
97_A240_A0.5881.00
105_L108_G0.5861.00
79_L137_L0.5811.00
62_G66_V0.5811.00
88_A150_V0.5791.00
138_R254_E0.5791.00
186_A230_L0.5781.00
75_S115_T0.5771.00
181_I184_L0.5771.00
51_Q176_V0.5751.00
187_W274_R0.5751.00
238_E253_Y0.5751.00
55_V238_E0.5741.00
189_M222_I0.5741.00
135_L139_G0.5731.00
56_N253_Y0.5721.00
86_V103_A0.5721.00
260_A278_T0.5641.00
170_L173_P0.5641.00
228_G231_A0.5631.00
119_V126_A0.5601.00
123_R217_N0.5601.00
65_L189_M0.5591.00
55_V241_R0.5581.00
87_A235_G0.5571.00
225_S228_G0.5571.00
50_L53_T0.5531.00
189_M193_T0.5481.00
209_T216_V0.5471.00
66_V71_G0.5441.00
220_K223_V0.5441.00
207_A211_L0.5431.00
61_V183_F0.5431.00
81_A249_A0.5421.00
251_T254_E0.5391.00
178_I182_V0.5381.00
147_G150_V0.5381.00
131_L135_L0.5361.00
264_G278_T0.5351.00
86_V104_A0.5351.00
90_I94_E0.5341.00
178_I181_I0.5341.00
263_L313_A0.5331.00
292_L297_V0.5321.00
61_V187_W0.5311.00
156_E160_L0.5301.00
57_A61_V0.5301.00
134_M254_E0.5291.00
95_V100_A0.5281.00
52_Q290_N0.5281.00
261_V278_T0.5261.00
137_L141_T0.5251.00
306_K314_V0.5251.00
82_L107_L0.5251.00
182_V186_A0.5241.00
277_G281_G0.5231.00
92_G95_V0.5231.00
141_T145_T0.5231.00
256_D303_M0.5231.00
45_N48_N0.5211.00
93_I96_N0.5201.00
56_N60_A0.5171.00
201_A208_A0.5171.00
131_L134_M0.5161.00
146_N149_P0.5151.00
276_V279_L0.5111.00
172_V177_W0.5111.00
291_G294_L0.5071.00
86_V108_G0.5061.00
118_I124_V0.5041.00
140_V144_Y0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4g1uA 2 0.8193 97.5 0.865 Contact Map
2qi9A 2 0.9097 97.3 0.87 Contact Map
2nq2A 2 0.8567 97 0.876 Contact Map
2kogA 1 0.1246 11.4 0.955 Contact Map
1u7gA 3 0.5826 11.3 0.955 Contact Map
4j72A 2 0.676 8.7 0.957 Contact Map
2m8rA 1 0.1308 6.4 0.959 Contact Map
2onkC 2 0.7352 5 0.961 Contact Map
4dveA 3 0.5483 4.1 0.963 Contact Map
1pw4A 1 0.5826 3.8 0.963 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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