TLDD - ECOLI - GREMLIN Contacts

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TLDD - Metalloprotease TldD

UniProt:	P0AGG8	Sequences: MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12826
Length:	481 (433)
Sequences:	4534 (2904)
Seq/√Len:	139.5

ECOLI - TLDD PMBA
SULSO - Q97YZ8 TLDD Q97YZ7 Q7LXP5 Q97ZU9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
325_E	330_K	4.268	1.00
322_V	325_E	4.102	1.00
384_Y	414_E	3.941	1.00
299_D	320_Y	3.720	1.00
386_I	422_V	3.564	1.00
383_E	415_N	3.343	1.00
288_L	292_E	3.340	1.00
439_S	471_K	3.306	1.00
439_S	473_D	3.252	1.00
247_T	474_N	3.215	1.00
374_T	377_E	3.122	1.00
140_R	224_D	3.113	1.00
382_V	413_I	3.072	1.00
414_E	419_T	3.070	1.00
284_Q	287_E	3.022	1.00
130_S	133_E	2.965	1.00
412_L	420_K	2.907	1.00
241_V	420_K	2.871	1.00
414_E	420_K	2.765	1.00
384_Y	412_L	2.582	1.00
136_D	140_R	2.487	1.00
178_D	310_A	2.448	1.00
42_S	165_L	2.435	1.00
151_R	193_E	2.388	1.00
192_E	195_G	2.374	1.00
77_G	96_A	2.321	1.00
378_I	469_T	2.305	1.00
23_A	86_L	2.229	1.00
412_L	419_T	2.229	1.00
295_T	322_V	2.204	1.00
374_T	443_N	2.157	1.00
229_E	232_R	2.133	1.00
297_V	369_L	2.131	1.00
22_F	26_G	2.121	1.00
143_K	147_E	2.077	1.00
297_V	320_Y	2.041	1.00
27_Q	90_E	2.023	1.00
380_E	417_K	2.012	1.00
379_I	413_I	1.990	1.00
293_L	326_N	1.979	1.00
293_L	441_V	1.978	1.00
228_K	232_R	1.964	1.00
288_L	436_Q	1.942	1.00
444_D	469_T	1.925	1.00
373_S	377_E	1.919	1.00
292_E	326_N	1.911	1.00
295_T	326_N	1.871	1.00
152_V	191_V	1.856	1.00
90_E	94_Q	1.822	1.00
167_L	175_L	1.822	1.00
290_A	435_M	1.820	1.00
191_V	234_A	1.808	1.00
222_R	225_A	1.807	1.00
83_Q	88_A	1.785	1.00
434_T	472_V	1.781	1.00
148_A	228_K	1.775	1.00
309_V	318_G	1.767	1.00
248_M	477_V	1.764	1.00
251_V	382_V	1.764	1.00
134_K	159_L	1.758	1.00
319_Q	345_T	1.756	1.00
36_G	171_T	1.741	1.00
209_G	212_F	1.733	1.00
375_P	469_T	1.732	1.00
334_Q	344_M	1.716	1.00
144_V	224_D	1.703	1.00
94_Q	98_T	1.698	1.00
232_R	236_V	1.695	1.00
27_Q	30_E	1.693	1.00
28_L	36_G	1.672	1.00
75_K	105_D	1.668	1.00
378_I	440_M	1.665	1.00
381_S	440_M	1.635	1.00
382_V	471_K	1.626	1.00
402_K	430_S	1.610	1.00
148_A	231_V	1.599	1.00
413_I	419_T	1.584	1.00
191_V	235_L	1.581	1.00
176_A	311_I	1.578	1.00
72_S	101_R	1.576	1.00
202_S	229_E	1.575	1.00
193_E	239_S	1.570	1.00
321_N	349_N	1.567	1.00
339_A	345_T	1.566	1.00
381_S	471_K	1.560	1.00
334_Q	338_N	1.533	1.00
136_D	139_R	1.529	1.00
85_S	88_A	1.524	1.00
433_E	437_Q	1.521	1.00
321_N	331_G	1.520	1.00
288_L	328_I	1.520	1.00
70_A	96_A	1.519	1.00
277_G	282_S	1.513	1.00
320_Y	367_Y	1.504	1.00
437_Q	474_N	1.503	1.00
144_V	227_A	1.502	1.00
375_P	379_I	1.482	1.00
42_S	64_Q	1.480	1.00
191_V	238_L	1.479	1.00
387_Y	413_I	1.478	1.00
133_E	136_D	1.478	1.00
139_R	143_K	1.469	1.00
249_P	471_K	1.468	1.00
269_L	323_L	1.467	1.00
50_L	55_I	1.450	1.00
91_Q	94_Q	1.448	1.00
152_V	235_L	1.444	1.00
411_Y	418_V	1.437	1.00
193_E	196_K	1.435	1.00
249_P	473_D	1.435	1.00
437_Q	473_D	1.431	1.00
385_G	413_I	1.419	1.00
251_V	378_I	1.417	1.00
430_S	433_E	1.415	1.00
169_A	175_L	1.406	1.00
373_S	440_M	1.384	1.00
66_V	81_A	1.381	1.00
165_L	177_A	1.377	1.00
23_A	26_G	1.374	1.00
370_P	445_L	1.364	1.00
253_G	387_Y	1.362	1.00
309_V	364_T	1.360	1.00
316_T	346_P	1.354	1.00
87_L	91_Q	1.352	1.00
323_L	333_M	1.352	1.00
19_Q	22_F	1.348	1.00
290_A	294_C	1.344	1.00
334_Q	342_M	1.342	1.00
27_Q	31_R	1.338	1.00
274_N	332_Y	1.336	1.00
142_D	146_R	1.335	1.00
145_A	227_A	1.329	1.00
134_K	161_G	1.325	1.00
165_L	179_V	1.296	1.00
52_D	154_E	1.293	1.00
28_L	32_R	1.293	1.00
135_L	139_R	1.290	1.00
297_V	322_V	1.290	1.00
275_R	342_M	1.287	1.00
198_E	423_K	1.280	1.00
72_S	100_V	1.274	1.00
138_L	157_A	1.271	1.00
153_Q	192_E	1.263	1.00
27_Q	94_Q	1.255	1.00
284_Q	432_I	1.254	1.00
263_E	266_G	1.254	1.00
204_G	226_W	1.248	1.00
301_T	318_G	1.237	1.00
251_V	471_K	1.235	1.00
326_N	330_K	1.229	1.00
286_G	330_K	1.229	1.00
72_S	97_R	1.225	1.00
373_S	381_S	1.223	1.00
227_A	231_V	1.218	1.00
79_A	92_S	1.218	1.00
271_G	334_Q	1.214	1.00
257_P	470_L	1.210	1.00
37_D	170_A	1.210	1.00
386_I	425_A	1.208	1.00
376_Q	380_E	1.202	1.00
375_P	378_I	1.199	1.00
295_T	369_L	1.186	1.00
212_F	304_D	1.186	1.00
294_C	441_V	1.184	1.00
145_A	189_V	1.178	1.00
224_D	228_K	1.177	1.00
308_S	365_N	1.177	1.00
25_L	36_G	1.177	1.00
397_D	402_K	1.162	0.99
316_T	348_G	1.157	0.99
48_W	55_I	1.155	0.99
251_V	413_I	1.153	0.99
46_E	134_K	1.142	0.99
88_A	92_S	1.141	0.99
316_T	336_K	1.140	0.99
31_R	94_Q	1.138	0.99
73_G	105_D	1.134	0.99
87_L	90_E	1.129	0.99
322_V	326_N	1.129	0.99
53_R	142_D	1.128	0.99
152_V	231_V	1.124	0.99
367_Y	466_G	1.122	0.99
387_Y	418_V	1.122	0.99
225_A	229_E	1.121	0.99
367_Y	445_L	1.121	0.99
132_E	136_D	1.120	0.99
163_Y	179_V	1.112	0.99
320_Y	369_L	1.112	0.99
261_L	368_M	1.110	0.99
351_R	362_R	1.109	0.99
322_V	330_K	1.105	0.99
407_T	410_A	1.103	0.99
21_L	169_A	1.103	0.99
295_T	325_E	1.102	0.99
39_Y	352_R	1.101	0.99
433_E	436_Q	1.101	0.99
251_V	375_P	1.100	0.99
144_V	228_K	1.099	0.99
376_Q	417_K	1.095	0.99
23_A	27_Q	1.086	0.99
379_I	382_V	1.078	0.99
442_G	469_T	1.075	0.99
243_A	248_M	1.070	0.99
379_I	387_Y	1.069	0.99
37_D	69_R	1.065	0.99
441_V	470_L	1.065	0.99
42_S	62_I	1.060	0.99
209_G	304_D	1.057	0.99
189_V	231_V	1.051	0.99
375_P	443_N	1.044	0.99
25_L	171_T	1.044	0.99
26_G	30_E	1.042	0.99
447_L	466_G	1.041	0.99
161_G	210_Y	1.037	0.99
285_V	344_M	1.037	0.99
198_E	237_N	1.031	0.99
191_V	231_V	1.029	0.99
202_S	226_W	1.021	0.99
74_E	105_D	1.018	0.99
141_V	223_A	1.017	0.99
339_A	346_P	1.017	0.99
68_V	92_S	1.017	0.99
252_L	388_A	1.014	0.99
422_V	425_A	1.012	0.99
294_C	438_I	1.011	0.99
159_L	185_L	1.007	0.98
81_A	92_S	1.006	0.98
186_S	201_A	1.002	0.98
382_V	385_G	1.001	0.98
291_S	441_V	0.998	0.98
249_P	474_N	0.998	0.98
331_G	347_T	0.998	0.98
264_A	267_H	0.996	0.98
241_V	412_L	0.994	0.98
403_F	434_T	0.994	0.98
35_Y	172_D	0.994	0.98
231_V	235_L	0.986	0.98
170_A	174_T	0.980	0.98
296_V	366_T	0.980	0.98
440_M	471_K	0.975	0.98
300_G	309_V	0.974	0.98
46_E	161_G	0.970	0.98
50_L	139_R	0.967	0.98
192_E	197_R	0.966	0.98
140_R	143_K	0.965	0.98
296_V	324_I	0.965	0.98
334_Q	346_P	0.959	0.98
265_V	435_M	0.958	0.98
397_D	400_S	0.956	0.98
377_E	380_E	0.954	0.98
230_A	234_A	0.953	0.98
434_T	475_L	0.949	0.98
88_A	91_Q	0.949	0.98
189_V	234_A	0.946	0.98
248_M	412_L	0.946	0.98
277_G	283_G	0.940	0.98
378_I	442_G	0.932	0.97
294_C	368_M	0.929	0.97
300_G	318_G	0.913	0.97
321_N	347_T	0.913	0.97
140_R	144_V	0.912	0.97
19_Q	23_A	0.912	0.97
280_V	432_I	0.908	0.97
93_A	97_R	0.907	0.97
293_L	373_S	0.900	0.97
71_I	76_T	0.895	0.97
22_F	175_L	0.895	0.97
35_Y	168_V	0.893	0.97
44_Y	62_I	0.890	0.97
40_F	66_V	0.889	0.97
25_L	29_A	0.886	0.97
121_T	124_D	0.884	0.97
91_Q	95_A	0.881	0.96
200_G	230_A	0.879	0.96
77_G	100_V	0.878	0.96
38_L	66_V	0.877	0.96
65_G	78_F	0.877	0.96
23_A	90_E	0.876	0.96
28_L	33_L	0.873	0.96
119_L	123_V	0.873	0.96
335_D	361_P	0.871	0.96
290_A	324_I	0.870	0.96
375_P	444_D	0.869	0.96
79_A	96_A	0.867	0.96
375_P	387_Y	0.866	0.96
300_G	364_T	0.866	0.96
223_A	227_A	0.864	0.96
78_F	358_L	0.863	0.96
145_A	230_A	0.860	0.96
411_Y	421_P	0.852	0.96
41_Q	164_E	0.848	0.96
257_P	467_Q	0.847	0.96
167_L	177_A	0.846	0.96
349_N	364_T	0.846	0.96
121_T	304_D	0.845	0.96
67_G	352_R	0.838	0.95
141_V	185_L	0.838	0.95
246_G	384_Y	0.837	0.95
376_Q	379_I	0.830	0.95
251_V	387_Y	0.828	0.95
49_V	57_D	0.820	0.95
249_P	384_Y	0.817	0.95
300_G	321_N	0.817	0.95
283_G	287_E	0.809	0.94
302_M	367_Y	0.808	0.94
415_N	419_T	0.807	0.94
314_E	336_K	0.807	0.94
271_G	342_M	0.804	0.94
261_L	296_V	0.803	0.94
373_S	378_I	0.797	0.94
275_R	334_Q	0.796	0.94
266_G	366_T	0.796	0.94
144_V	147_E	0.796	0.94
151_R	235_L	0.796	0.94
168_V	176_A	0.794	0.94
247_T	476_T	0.794	0.94
396_V	405_F	0.793	0.94
24_I	89_L	0.791	0.94
51_E	56_K	0.791	0.94
243_A	386_I	0.790	0.94
363_M	366_T	0.788	0.94
417_K	420_K	0.787	0.93
387_Y	469_T	0.785	0.93
81_A	88_A	0.785	0.93
263_E	267_H	0.783	0.93
44_Y	163_Y	0.783	0.93
200_G	234_A	0.781	0.93
137_I	210_Y	0.781	0.93
64_Q	84_I	0.781	0.93
49_V	158_S	0.778	0.93
307_G	464_G	0.778	0.93
382_V	439_S	0.775	0.93
394_G	405_F	0.774	0.93
403_F	429_G	0.774	0.93
55_I	135_L	0.767	0.93
123_V	163_Y	0.766	0.93
110_T	340_R	0.763	0.92
137_I	140_R	0.763	0.92
35_Y	171_T	0.762	0.92
302_M	308_S	0.757	0.92
172_D	336_K	0.756	0.92
389_P	411_Y	0.755	0.92
262_H	267_H	0.754	0.92
388_A	427_L	0.753	0.92
335_D	338_N	0.752	0.92
333_M	363_M	0.751	0.92
244_P	384_Y	0.750	0.92
373_S	443_N	0.749	0.92
367_Y	447_L	0.747	0.92
40_F	64_Q	0.747	0.92
144_V	148_A	0.747	0.92
413_I	418_V	0.745	0.91
110_T	113_A	0.742	0.91
228_K	231_V	0.741	0.91
225_A	228_K	0.741	0.91
256_W	259_V	0.741	0.91
299_D	367_Y	0.740	0.91
248_M	386_I	0.739	0.91
129_M	210_Y	0.737	0.91
261_L	294_C	0.736	0.91
298_D	321_N	0.734	0.91
33_L	72_S	0.733	0.91
269_L	281_F	0.732	0.91
240_A	423_K	0.732	0.91
379_I	384_Y	0.731	0.91
66_V	89_L	0.731	0.91
257_P	368_M	0.730	0.91
269_L	329_L	0.730	0.91
91_Q	98_T	0.730	0.91
256_W	391_F	0.726	0.90
24_I	86_L	0.726	0.90
189_V	230_A	0.725	0.90
241_V	414_E	0.725	0.90
300_G	308_S	0.725	0.90
145_A	231_V	0.724	0.90
410_A	422_V	0.724	0.90
266_G	362_R	0.721	0.90
69_R	314_E	0.720	0.90
318_G	364_T	0.720	0.90
242_A	424_G	0.717	0.90
438_I	470_L	0.715	0.90
29_A	171_T	0.715	0.90
166_I	178_D	0.715	0.90
205_G	306_R	0.715	0.90
338_N	361_P	0.713	0.90
334_Q	339_A	0.711	0.89
326_N	345_T	0.711	0.89
140_R	223_A	0.710	0.89
249_P	382_V	0.709	0.89
302_M	305_R	0.707	0.89
379_I	418_V	0.706	0.89
290_A	438_I	0.705	0.89
136_D	143_K	0.704	0.89
350_G	361_P	0.703	0.89
392_G	408_S	0.701	0.89
275_R	338_N	0.697	0.89
21_L	38_L	0.694	0.88
144_V	231_V	0.693	0.88
141_V	187_V	0.692	0.88
378_I	382_V	0.692	0.88
119_L	122_S	0.692	0.88
250_V	475_L	0.688	0.88
445_L	466_G	0.687	0.88
281_F	329_L	0.685	0.88
97_R	101_R	0.685	0.88
52_D	155_V	0.684	0.88
267_H	270_E	0.683	0.88
151_R	238_L	0.680	0.87
148_A	235_L	0.680	0.87
202_S	230_A	0.677	0.87
248_M	422_V	0.676	0.87
252_L	391_F	0.676	0.87
33_L	97_R	0.676	0.87
437_Q	475_L	0.675	0.87
235_L	238_L	0.674	0.87
129_M	133_E	0.674	0.87
22_F	29_A	0.671	0.87
158_S	186_S	0.670	0.87
148_A	151_R	0.670	0.87
206_G	212_F	0.669	0.86
287_E	328_I	0.668	0.86
391_F	395_Q	0.667	0.86
271_G	275_R	0.667	0.86
43_S	164_E	0.666	0.86
396_V	431_G	0.664	0.86
109_Q	113_A	0.662	0.86
291_S	294_C	0.662	0.86
233_M	253_G	0.660	0.86
391_F	394_G	0.659	0.86
279_S	332_Y	0.658	0.86
386_I	412_L	0.658	0.86
33_L	70_A	0.657	0.85
52_D	146_R	0.656	0.85
393_G	404_V	0.656	0.85
47_S	59_S	0.656	0.85
20_D	23_A	0.656	0.85
161_G	183_V	0.654	0.85
274_N	279_S	0.654	0.85
25_L	38_L	0.653	0.85
39_Y	166_I	0.652	0.85
29_A	33_L	0.651	0.85
380_E	384_Y	0.650	0.85
335_D	360_M	0.647	0.85
112_G	115_E	0.642	0.84
368_M	470_L	0.642	0.84
43_S	162_V	0.641	0.84
253_G	389_P	0.641	0.84
243_A	246_G	0.640	0.84
48_W	131_R	0.640	0.84
123_V	181_P	0.638	0.84
70_A	77_G	0.636	0.84
379_I	383_E	0.636	0.84
21_L	40_F	0.634	0.83
47_S	158_S	0.633	0.83
260_L	391_F	0.632	0.83
31_R	90_E	0.631	0.83
164_E	180_R	0.630	0.83
338_N	342_M	0.629	0.83
129_M	134_K	0.628	0.83
319_Q	331_G	0.627	0.83
261_L	470_L	0.626	0.83
289_V	436_Q	0.625	0.83
254_A	469_T	0.625	0.83
31_R	97_R	0.624	0.82
336_K	340_R	0.623	0.82
262_H	362_R	0.621	0.82
265_V	289_V	0.621	0.82
121_T	125_P	0.620	0.82
77_G	99_I	0.619	0.82
86_L	90_E	0.616	0.82
73_G	101_R	0.616	0.82
406_S	424_G	0.615	0.82
382_V	387_Y	0.615	0.82
149_D	235_L	0.613	0.81
262_H	266_G	0.612	0.81
385_G	418_V	0.612	0.81
285_V	332_Y	0.611	0.81
380_E	383_E	0.611	0.81
45_H	160_S	0.610	0.81
325_E	328_I	0.609	0.81
413_I	471_K	0.607	0.81
117_S	310_A	0.607	0.81
285_V	330_K	0.607	0.81
82_D	85_S	0.605	0.80
37_D	67_G	0.605	0.80
393_G	429_G	0.605	0.80
239_S	421_P	0.605	0.80
383_E	419_T	0.604	0.80
301_T	320_Y	0.602	0.80
395_Q	405_F	0.602	0.80
133_E	137_I	0.601	0.80
28_L	70_A	0.601	0.80
256_W	388_A	0.601	0.80
290_A	296_V	0.600	0.80
391_F	405_F	0.598	0.80
407_T	425_A	0.597	0.80
58_G	139_R	0.595	0.79
33_L	36_G	0.595	0.79
27_Q	86_L	0.593	0.79
235_L	239_S	0.592	0.79
442_G	445_L	0.591	0.79
296_V	368_M	0.591	0.79
111_L	114_V	0.590	0.79
288_L	326_N	0.590	0.79
272_D	276_R	0.588	0.79
371_G	443_N	0.587	0.78
25_L	28_L	0.585	0.78
120_Y	124_D	0.584	0.78
275_R	341_L	0.584	0.78
268_G	280_V	0.583	0.78
264_A	405_F	0.582	0.78
61_N	287_E	0.582	0.78
285_V	331_G	0.582	0.78
144_V	223_A	0.582	0.78
262_H	363_M	0.580	0.78
109_Q	112_G	0.580	0.78
145_A	155_V	0.579	0.77
270_E	363_M	0.579	0.77
24_I	31_R	0.579	0.77
337_L	341_L	0.578	0.77
152_V	234_A	0.578	0.77
147_E	228_K	0.577	0.77
262_H	270_E	0.574	0.77
120_Y	125_P	0.574	0.77
142_D	157_A	0.573	0.77
395_Q	404_V	0.573	0.77
244_P	248_M	0.572	0.77
147_E	150_K	0.571	0.77
366_T	467_Q	0.571	0.77
267_H	362_R	0.571	0.77
196_K	239_S	0.571	0.77
404_V	428_I	0.569	0.76
26_G	29_A	0.568	0.76
236_V	411_Y	0.568	0.76
438_I	442_G	0.567	0.76
45_H	63_D	0.567	0.76
384_Y	415_N	0.567	0.76
432_I	436_Q	0.566	0.76
251_V	379_I	0.565	0.76
372_K	443_N	0.563	0.76
39_Y	164_E	0.562	0.75
232_R	235_L	0.560	0.75
122_S	179_V	0.558	0.75
392_G	426_T	0.558	0.75
269_L	333_M	0.556	0.75
94_Q	228_K	0.556	0.75
138_L	159_L	0.555	0.74
305_R	308_S	0.553	0.74
34_D	72_S	0.553	0.74
114_V	172_D	0.553	0.74
313_D	351_R	0.551	0.74
374_T	442_G	0.551	0.74
333_M	366_T	0.551	0.74
377_E	381_S	0.550	0.74
283_G	332_Y	0.550	0.74
265_V	324_I	0.547	0.73
404_V	426_T	0.547	0.73
122_S	125_P	0.547	0.73
326_N	369_L	0.546	0.73
410_A	425_A	0.545	0.73
29_A	101_R	0.545	0.73
335_D	350_G	0.544	0.73
253_G	257_P	0.544	0.73
134_K	210_Y	0.543	0.73
45_H	162_V	0.543	0.73
401_G	430_S	0.542	0.73
334_Q	361_P	0.541	0.73
362_R	463_V	0.541	0.73
44_Y	60_Y	0.540	0.72
246_G	386_I	0.539	0.72
86_L	89_L	0.539	0.72
274_N	342_M	0.539	0.72
270_E	362_R	0.538	0.72
27_Q	93_A	0.538	0.72
147_E	224_D	0.538	0.72
119_L	303_V	0.536	0.72
467_Q	470_L	0.536	0.72
393_G	426_T	0.535	0.72
155_V	189_V	0.535	0.72
378_I	418_V	0.534	0.72
381_S	439_S	0.534	0.72
104_G	107_K	0.534	0.72
272_D	360_M	0.533	0.72
80_Y	352_R	0.533	0.72
241_V	419_T	0.532	0.71
48_W	134_K	0.531	0.71
323_L	366_T	0.531	0.71
291_S	295_T	0.530	0.71
44_Y	165_L	0.530	0.71
50_L	138_L	0.529	0.71
260_L	431_G	0.528	0.71
384_Y	419_T	0.527	0.71
108_V	111_L	0.527	0.71
66_V	88_A	0.526	0.71
268_G	432_I	0.526	0.71
262_H	463_V	0.526	0.71
123_V	126_L	0.525	0.70
37_D	78_F	0.525	0.70
407_T	427_L	0.525	0.70
241_V	421_P	0.525	0.70
445_L	467_Q	0.524	0.70
276_R	400_S	0.523	0.70
126_L	210_Y	0.523	0.70
260_L	472_V	0.522	0.70
442_G	468_P	0.522	0.70
108_V	113_A	0.521	0.70
312_D	348_G	0.519	0.70
224_D	227_A	0.519	0.70
297_V	367_Y	0.518	0.69
121_T	209_G	0.518	0.69
363_M	394_G	0.517	0.69
160_S	184_R	0.516	0.69
258_G	446_K	0.516	0.69
120_Y	123_V	0.516	0.69
274_N	329_L	0.515	0.69
406_S	426_T	0.515	0.69
145_A	187_V	0.515	0.69
128_S	133_E	0.515	0.69
143_K	437_Q	0.514	0.69
96_A	100_V	0.514	0.69
390_N	408_S	0.513	0.69
49_V	156_T	0.513	0.69
84_I	88_A	0.512	0.69
264_A	396_V	0.512	0.69
270_E	335_D	0.512	0.69
377_E	443_N	0.511	0.68
249_P	383_E	0.511	0.68
116_H	120_Y	0.511	0.68
126_L	161_G	0.511	0.68
39_Y	65_G	0.510	0.68
70_A	93_A	0.510	0.68
370_P	443_N	0.509	0.68
265_V	294_C	0.508	0.68
229_E	233_M	0.508	0.68
32_R	97_R	0.508	0.68
55_I	58_G	0.508	0.68
380_E	415_N	0.508	0.68
256_W	406_S	0.507	0.68
277_G	284_Q	0.506	0.68
265_V	366_T	0.506	0.68
266_G	363_M	0.505	0.67
339_A	344_M	0.503	0.67
19_Q	26_G	0.503	0.67
291_S	326_N	0.503	0.67
252_L	257_P	0.502	0.67
298_D	323_L	0.502	0.67
240_A	421_P	0.501	0.67
124_D	128_S	0.501	0.67
150_K	228_K	0.500	0.67
381_S	413_I	0.500	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qtdA	2	0.9064	100	0.164	Contact Map
1vl4A	2	0.8794	100	0.181	Contact Map
1vpbA	2	0.894	100	0.181	Contact Map
3tv9A	2	0.894	100	0.184	Contact Map
2plgA	4	0.2931	12.2	0.974	Contact Map
4hvzA	5	0.3846	7.8	0.977	Contact Map
4htiA	1	0.1788	6.8	0.977	Contact Map
2zcwA	2	0.1164	6.3	0.978	Contact Map
3e97A	2	0.1102	6.2	0.978	Contact Map
3b02A	2	0.1247	5	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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