MLTF - ECOLI - GREMLIN Contacts

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MLTF - Membrane-bound lytic murein transglycosylase F

UniProt:	P0AGC5	Sequences: MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMLDARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11373
Length:	518 (436)
Sequences:	854 (622)
Seq/√Len:	29.8

ECOLI - MLTF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
48_S	102_A	4.852	1.00
292_K	296_E	4.301	1.00
74_F	244_A	4.243	1.00
44_E	83_K	3.917	1.00
51_H	55_T	3.816	1.00
50_I	55_T	3.605	1.00
50_I	53_P	3.417	1.00
233_S	245_L	3.398	1.00
112_N	159_V	3.383	1.00
52_T	55_T	3.301	1.00
23_W	26_I	3.297	1.00
395_R	406_D	3.248	1.00
73_Q	248_F	3.240	1.00
121_P	232_F	3.203	1.00
307_L	357_V	2.984	1.00
398_T	403_G	2.939	1.00
370_S	406_D	2.882	1.00
51_H	57_N	2.819	1.00
192_V	200_T	2.764	1.00
370_S	392_L	2.749	1.00
298_Y	350_E	2.700	1.00
47_V	71_A	2.694	1.00
401_T	414_R	2.560	0.99
374_N	377_I	2.499	0.99
298_Y	354_S	2.471	0.99
122_G	249_F	2.470	0.99
398_T	414_R	2.428	0.99
119_Y	232_F	2.314	0.99
122_G	246_L	2.297	0.99
433_R	436_E	2.294	0.99
430_G	434_G	2.270	0.99
53_P	57_N	2.256	0.99
404_N	407_S	2.249	0.99
112_N	121_P	2.244	0.99
111_Y	230_T	2.185	0.98
373_E	377_I	2.185	0.98
153_T	197_L	2.182	0.98
424_Y	434_G	2.181	0.98
421_K	424_Y	2.089	0.98
430_G	433_R	2.076	0.98
233_S	242_S	2.063	0.98
46_R	85_T	2.059	0.97
21_A	26_I	2.057	0.97
42_R	103_D	2.049	0.97
52_T	57_N	2.037	0.97
44_E	81_K	2.033	0.97
121_P	230_T	2.032	0.97
305_R	448_Q	2.030	0.97
110_V	115_R	1.999	0.97
123_P	246_L	1.974	0.97
130_Q	163_D	1.961	0.97
115_R	159_V	1.954	0.97
403_G	414_R	1.943	0.96
424_Y	430_G	1.914	0.96
120_Q	242_S	1.833	0.95
191_D	196_K	1.816	0.95
154_V	164_L	1.803	0.95
396_A	400_K	1.783	0.94
59_I	62_K	1.769	0.94
98_D	119_Y	1.765	0.94
134_Y	199_Y	1.759	0.94
420_Q	424_Y	1.757	0.94
379_F	391_M	1.739	0.93
110_V	203_D	1.729	0.93
131_Q	134_Y	1.728	0.93
160_V	203_D	1.728	0.93
110_V	159_V	1.720	0.93
367_V	391_M	1.719	0.93
390_H	394_A	1.686	0.92
368_P	395_R	1.675	0.92
205_V	266_L	1.666	0.92
50_I	57_N	1.665	0.92
124_T	249_F	1.654	0.92
115_R	121_P	1.652	0.91
77_Y	251_E	1.650	0.91
242_S	246_L	1.650	0.91
434_G	441_V	1.649	0.91
419_S	424_Y	1.641	0.91
330_M	349_A	1.631	0.91
418_L	430_G	1.628	0.91
98_D	118_N	1.603	0.90
386_M	437_A	1.585	0.90
143_T	146_N	1.577	0.89
69_E	265_Y	1.571	0.89
295_F	311_A	1.568	0.89
364_M	380_A	1.559	0.89
112_N	203_D	1.540	0.88
22_L	26_I	1.538	0.88
112_N	115_R	1.534	0.88
367_V	371_V	1.533	0.88
21_A	25_S	1.531	0.88
440_Y	444_I	1.528	0.88
48_S	93_L	1.525	0.88
123_P	249_F	1.522	0.88
310_I	360_L	1.519	0.88
400_K	426_K	1.509	0.87
135_K	195_G	1.506	0.87
353_I	356_G	1.504	0.87
188_L	197_L	1.504	0.87
311_A	330_M	1.503	0.87
295_F	353_I	1.481	0.86
133_V	192_V	1.465	0.86
55_T	58_E	1.465	0.86
100_G	103_D	1.464	0.86
131_Q	219_V	1.452	0.85
47_V	402_K	1.442	0.85
252_M	258_L	1.436	0.84
85_T	102_A	1.428	0.84
122_G	245_L	1.427	0.84
151_Q	198_D	1.417	0.84
172_F	177_W	1.412	0.83
173_P	177_W	1.411	0.83
418_L	424_Y	1.410	0.83
115_R	203_D	1.410	0.83
372_P	375_E	1.391	0.82
207_I	219_V	1.389	0.82
71_A	82_L	1.382	0.82
390_H	393_D	1.376	0.82
130_Q	134_Y	1.376	0.82
131_Q	222_D	1.376	0.82
48_S	87_R	1.375	0.82
392_L	396_A	1.354	0.81
66_L	266_L	1.339	0.80
134_Y	248_F	1.327	0.79
434_G	444_I	1.325	0.79
361_Q	365_S	1.325	0.79
105_L	375_E	1.324	0.79
193_I	216_E	1.312	0.78
202_A	207_I	1.305	0.78
69_E	261_I	1.303	0.78
421_K	434_G	1.301	0.78
150_E	199_Y	1.284	0.77
246_L	249_F	1.284	0.77
68_Y	82_L	1.282	0.77
328_R	347_T	1.282	0.77
171_K	174_E	1.281	0.77
420_Q	434_G	1.278	0.77
68_Y	72_K	1.278	0.77
325_T	334_T	1.272	0.76
190_E	194_E	1.266	0.76
50_I	54_L	1.266	0.76
307_L	311_A	1.264	0.76
275_V	278_R	1.261	0.76
424_Y	433_R	1.261	0.76
159_V	203_D	1.259	0.76
419_S	435_H	1.247	0.75
354_S	358_R	1.246	0.75
54_L	121_P	1.244	0.75
185_S	206_A	1.242	0.74
47_V	343_I	1.227	0.74
294_L	350_E	1.214	0.73
434_G	440_Y	1.212	0.73
363_M	383_A	1.206	0.72
180_D	183_K	1.205	0.72
434_G	437_A	1.205	0.72
48_S	97_L	1.188	0.71
72_K	76_D	1.182	0.71
113_S	116_V	1.177	0.70
430_G	436_E	1.170	0.70
415_L	432_A	1.168	0.70
252_M	257_T	1.167	0.70
333_L	355_G	1.166	0.70
39_I	80_V	1.165	0.70
46_R	83_K	1.159	0.69
67_D	106_A	1.145	0.68
94_F	97_L	1.140	0.68
34_N	42_R	1.138	0.68
73_Q	252_M	1.135	0.68
424_Y	427_L	1.134	0.67
364_M	373_E	1.131	0.67
69_E	264_K	1.129	0.67
412_K	442_E	1.128	0.67
311_A	360_L	1.121	0.67
327_V	335_K	1.118	0.66
328_R	352_S	1.114	0.66
327_V	346_R	1.114	0.66
424_Y	441_V	1.105	0.65
130_Q	227_Q	1.104	0.65
128_V	134_Y	1.103	0.65
367_V	406_D	1.100	0.65
430_G	441_V	1.097	0.65
428_T	434_G	1.095	0.65
343_I	346_R	1.092	0.65
45_L	104_L	1.092	0.65
392_L	395_R	1.091	0.64
418_L	433_R	1.090	0.64
67_D	125_Y	1.090	0.64
20_V	23_W	1.081	0.64
390_H	397_L	1.069	0.63
420_Q	430_G	1.067	0.63
193_I	202_A	1.058	0.62
215_P	418_L	1.057	0.62
51_H	58_E	1.050	0.61
91_S	157_G	1.043	0.61
299_A	302_I	1.042	0.61
104_L	245_L	1.041	0.61
421_K	430_G	1.041	0.61
411_V	414_R	1.039	0.61
37_A	40_Q	1.033	0.60
361_Q	364_M	1.032	0.60
419_S	434_G	1.032	0.60
317_W	332_M	1.030	0.60
51_H	56_Y	1.030	0.60
276_D	316_H	1.027	0.60
113_S	166_T	1.022	0.59
131_Q	207_I	1.003	0.58
18_L	22_L	0.998	0.57
302_I	364_M	0.994	0.57
87_R	96_D	0.993	0.57
330_M	353_I	0.992	0.57
161_V	165_Q	0.989	0.57
333_L	348_D	0.988	0.57
37_A	240_T	0.981	0.56
421_K	440_Y	0.980	0.56
323_S	333_L	0.979	0.56
14_L	24_P	0.978	0.56
313_Q	356_G	0.976	0.56
327_V	334_T	0.972	0.55
298_Y	301_E	0.964	0.55
50_I	56_Y	0.962	0.55
419_S	427_L	0.959	0.54
379_F	383_A	0.957	0.54
135_K	198_D	0.957	0.54
49_T	107_A	0.956	0.54
109_L	333_L	0.953	0.54
32_A	35_R	0.950	0.54
93_L	105_L	0.950	0.54
447_Y	451_L	0.945	0.53
330_M	342_G	0.942	0.53
430_G	437_A	0.941	0.53
14_L	21_A	0.941	0.53
272_F	275_V	0.935	0.53
187_E	202_A	0.931	0.52
54_L	67_D	0.930	0.52
88_Q	92_Q	0.930	0.52
131_Q	419_S	0.924	0.52
201_I	223_I	0.922	0.51
50_I	58_E	0.919	0.51
349_A	390_H	0.918	0.51
302_I	360_L	0.918	0.51
325_T	333_L	0.916	0.51
111_Y	121_P	0.913	0.51
317_W	346_R	0.913	0.51
338_A	346_R	0.913	0.51
120_Q	239_N	0.908	0.50
52_T	202_A	0.908	0.50
128_V	131_Q	0.904	0.50
423_Y	427_L	0.904	0.50
111_Y	116_V	0.901	0.50
424_Y	437_A	0.897	0.49
229_V	266_L	0.896	0.49
325_T	338_A	0.891	0.49
78_L	359_Y	0.889	0.49
349_A	394_A	0.889	0.49
210_F	213_V	0.879	0.48
427_L	434_G	0.879	0.48
437_A	440_Y	0.878	0.48
111_Y	232_F	0.877	0.48
154_V	158_H	0.876	0.48
97_L	121_P	0.875	0.48
370_S	399_A	0.867	0.47
272_F	322_T	0.866	0.47
186_A	206_A	0.864	0.47
172_F	175_L	0.864	0.47
288_L	304_W	0.863	0.47
17_L	25_S	0.863	0.47
21_A	24_P	0.861	0.47
46_R	86_V	0.861	0.47
129_S	134_Y	0.860	0.47
132_L	223_I	0.859	0.46
52_T	56_Y	0.858	0.46
112_N	160_V	0.857	0.46
112_N	162_N	0.857	0.46
48_S	105_L	0.854	0.46
323_S	356_G	0.854	0.46
340_S	362_D	0.852	0.46
441_V	444_I	0.848	0.46
399_A	405_P	0.847	0.46
252_M	255_D	0.844	0.45
446_K	449_I	0.844	0.45
325_T	346_R	0.841	0.45
245_L	287_V	0.841	0.45
47_V	92_Q	0.838	0.45
83_K	404_N	0.833	0.44
421_K	444_I	0.833	0.44
327_V	332_M	0.832	0.44
283_A	352_S	0.831	0.44
318_D	404_N	0.829	0.44
334_T	338_A	0.829	0.44
430_G	444_I	0.826	0.44
16_L	76_D	0.826	0.44
297_K	391_M	0.824	0.44
427_L	432_A	0.823	0.44
370_S	396_A	0.822	0.44
92_Q	204_S	0.819	0.43
73_Q	257_T	0.817	0.43
16_L	236_D	0.816	0.43
143_T	426_K	0.816	0.43
430_G	440_Y	0.815	0.43
102_A	355_G	0.815	0.43
348_D	351_Q	0.814	0.43
147_L	197_L	0.812	0.43
269_G	404_N	0.811	0.43
424_Y	444_I	0.810	0.43
97_L	105_L	0.808	0.43
41_A	118_N	0.808	0.43
235_L	297_K	0.807	0.42
125_Y	153_T	0.806	0.42
367_V	383_A	0.804	0.42
418_L	434_G	0.799	0.42
283_A	287_V	0.799	0.42
339_Q	356_G	0.790	0.41
153_T	383_A	0.790	0.41
39_I	43_G	0.790	0.41
94_F	115_R	0.788	0.41
141_P	220_A	0.786	0.41
397_L	401_T	0.785	0.41
94_F	119_Y	0.785	0.41
104_L	410_D	0.779	0.40
418_L	421_K	0.778	0.40
206_A	423_Y	0.778	0.40
120_Q	268_H	0.777	0.40
64_F	210_F	0.777	0.40
317_W	327_V	0.776	0.40
424_Y	440_Y	0.776	0.40
313_Q	380_A	0.776	0.40
71_A	249_F	0.776	0.40
411_V	415_L	0.775	0.40
71_A	84_V	0.770	0.40
85_T	142_R	0.769	0.40
37_A	144_L	0.767	0.39
386_M	438_Y	0.764	0.39
229_V	356_G	0.760	0.39
289_P	334_T	0.758	0.39
333_L	351_Q	0.756	0.39
51_H	184_G	0.754	0.38
392_L	399_A	0.753	0.38
433_R	441_V	0.750	0.38
349_A	365_S	0.748	0.38
96_D	101_N	0.747	0.38
283_A	311_A	0.746	0.38
13_I	17_L	0.745	0.38
337_T	341_L	0.742	0.37
332_M	346_R	0.742	0.37
87_R	209_L	0.741	0.37
124_T	246_L	0.741	0.37
213_V	291_L	0.740	0.37
333_L	343_I	0.739	0.37
244_A	247_D	0.739	0.37
258_L	267_G	0.738	0.37
266_L	270_D	0.738	0.37
214_H	296_E	0.738	0.37
148_T	343_I	0.736	0.37
169_E	176_S	0.735	0.37
134_Y	220_A	0.735	0.37
77_Y	247_D	0.734	0.37
129_S	133_V	0.733	0.37
42_R	348_D	0.732	0.37
152_L	177_W	0.731	0.37
429_Y	433_R	0.730	0.37
150_E	198_D	0.728	0.36
393_D	397_L	0.727	0.36
246_L	250_N	0.726	0.36
189_M	395_R	0.725	0.36
355_G	359_Y	0.724	0.36
15_A	22_L	0.724	0.36
304_W	390_H	0.720	0.36
125_Y	204_S	0.720	0.36
319_A	330_M	0.715	0.36
16_L	20_V	0.714	0.35
70_L	390_H	0.711	0.35
141_P	221_L	0.711	0.35
127_S	228_P	0.711	0.35
394_A	397_L	0.711	0.35
115_R	356_G	0.709	0.35
364_M	377_I	0.709	0.35
130_Q	200_T	0.707	0.35
199_Y	248_F	0.707	0.35
424_Y	432_A	0.704	0.35
155_A	158_H	0.704	0.35
171_K	175_L	0.702	0.35
83_K	86_V	0.701	0.35
35_R	100_G	0.701	0.35
336_N	339_Q	0.700	0.34
321_A	333_L	0.699	0.34
154_V	161_V	0.699	0.34
419_S	430_G	0.697	0.34
299_A	399_A	0.697	0.34
400_K	423_Y	0.696	0.34
187_E	191_D	0.695	0.34
389_A	396_A	0.694	0.34
317_W	334_T	0.694	0.34
261_I	348_D	0.694	0.34
93_L	298_Y	0.691	0.34
340_S	363_M	0.691	0.34
289_P	292_K	0.690	0.34
12_G	26_I	0.689	0.34
36_I	80_V	0.688	0.34
48_S	359_Y	0.687	0.34
263_E	267_G	0.686	0.33
128_V	211_Q	0.686	0.33
48_S	88_Q	0.685	0.33
327_V	416_P	0.684	0.33
346_R	352_S	0.684	0.33
349_A	397_L	0.681	0.33
419_S	436_E	0.680	0.33
136_V	218_A	0.679	0.33
115_R	200_T	0.679	0.33
346_R	351_Q	0.678	0.33
412_K	415_L	0.677	0.33
367_V	388_Y	0.676	0.33
280_F	386_M	0.674	0.33
157_G	318_D	0.671	0.32
305_R	449_I	0.671	0.32
424_Y	436_E	0.671	0.32
379_F	403_G	0.671	0.32
247_D	250_N	0.671	0.32
259_A	262_E	0.670	0.32
43_G	81_K	0.669	0.32
35_R	234_P	0.667	0.32
248_F	397_L	0.667	0.32
15_A	23_W	0.665	0.32
125_Y	131_Q	0.664	0.32
188_L	308_A	0.664	0.32
105_L	389_A	0.663	0.32
18_L	21_A	0.660	0.32
110_V	160_V	0.660	0.32
423_Y	426_K	0.659	0.32
341_L	362_D	0.659	0.32
264_K	269_G	0.659	0.32
320_Q	347_T	0.658	0.31
107_A	115_R	0.653	0.31
75_A	394_A	0.653	0.31
129_S	222_D	0.652	0.31
275_V	279_T	0.650	0.31
53_P	58_E	0.650	0.31
271_D	355_G	0.650	0.31
381_L	436_E	0.649	0.31
174_E	177_W	0.648	0.31
19_A	22_L	0.647	0.31
19_A	26_I	0.646	0.31
265_Y	295_F	0.645	0.31
40_Q	99_N	0.645	0.31
132_L	146_N	0.644	0.31
160_V	206_A	0.644	0.31
432_A	437_A	0.642	0.30
108_G	185_S	0.641	0.30
212_R	270_D	0.641	0.30
248_F	378_W	0.640	0.30
404_N	410_D	0.640	0.30
39_I	136_V	0.640	0.30
39_I	45_L	0.637	0.30
223_I	407_S	0.637	0.30
214_H	227_Q	0.635	0.30
305_R	378_W	0.634	0.30
35_R	335_K	0.632	0.30
73_Q	76_D	0.632	0.30
192_V	441_V	0.632	0.30
147_L	150_E	0.632	0.30
168_K	187_E	0.632	0.30
115_R	160_V	0.632	0.30
13_I	19_A	0.629	0.30
15_A	251_E	0.628	0.29
17_L	23_W	0.628	0.29
295_F	308_A	0.626	0.29
289_P	317_W	0.626	0.29
212_R	273_D	0.624	0.29
257_T	263_E	0.622	0.29
346_R	416_P	0.621	0.29
145_G	174_E	0.621	0.29
190_E	235_L	0.620	0.29
268_H	303_D	0.620	0.29
349_A	362_D	0.620	0.29
418_L	436_E	0.620	0.29
327_V	412_K	0.619	0.29
53_P	186_A	0.618	0.29
86_V	330_M	0.618	0.29
133_V	207_I	0.618	0.29
51_H	54_L	0.617	0.29
17_L	350_E	0.616	0.29
193_I	386_M	0.616	0.29
163_D	167_L	0.615	0.29
295_F	331_M	0.615	0.29
144_L	221_L	0.614	0.29
12_G	22_L	0.614	0.29
335_K	386_M	0.612	0.28
41_A	201_I	0.611	0.28
331_M	338_A	0.610	0.28
327_V	447_Y	0.608	0.28
418_L	429_Y	0.606	0.28
340_S	366_K	0.605	0.28
310_I	363_M	0.604	0.28
54_L	57_N	0.603	0.28
316_H	327_V	0.603	0.28
110_V	121_P	0.603	0.28
154_V	160_V	0.602	0.28
366_K	389_A	0.602	0.28
366_K	440_Y	0.601	0.28
254_E	310_I	0.601	0.28
418_L	422_P	0.600	0.28
269_G	273_D	0.599	0.28
422_P	436_E	0.597	0.27
19_A	23_W	0.597	0.27
311_A	317_W	0.596	0.27
66_L	144_L	0.596	0.27
364_M	383_A	0.594	0.27
349_A	389_A	0.594	0.27
325_T	418_L	0.593	0.27
45_L	128_V	0.592	0.27
38_A	229_V	0.591	0.27
176_S	180_D	0.589	0.27
310_I	381_L	0.588	0.27
30_G	201_I	0.588	0.27
152_L	176_S	0.587	0.27
199_Y	305_R	0.587	0.27
127_S	253_N	0.586	0.27
59_I	295_F	0.585	0.27
175_L	399_A	0.584	0.27
437_A	444_I	0.583	0.27
140_R	220_A	0.583	0.27
91_S	162_N	0.582	0.27
332_M	359_Y	0.582	0.27
141_P	204_S	0.582	0.27
59_I	64_F	0.582	0.27
126_Y	264_K	0.581	0.26
59_I	63_P	0.581	0.26
376_R	380_A	0.579	0.26
433_R	437_A	0.577	0.26
132_L	403_G	0.576	0.26
146_N	154_V	0.575	0.26
337_T	383_A	0.572	0.26
313_Q	331_M	0.572	0.26
108_G	427_L	0.572	0.26
144_L	167_L	0.572	0.26
294_L	297_K	0.571	0.26
316_H	325_T	0.570	0.26
156_P	180_D	0.569	0.26
139_Y	358_R	0.569	0.26
211_Q	376_R	0.567	0.26
403_G	413_Q	0.566	0.26
165_Q	217_L	0.565	0.26
69_E	72_K	0.565	0.26
335_K	413_Q	0.564	0.25
419_S	433_R	0.564	0.25
304_W	393_D	0.564	0.25
52_T	58_E	0.564	0.25
103_D	132_L	0.563	0.25
418_L	427_L	0.563	0.25
69_E	326_G	0.563	0.25
175_L	225_D	0.563	0.25
23_W	175_L	0.562	0.25
15_A	20_V	0.562	0.25
288_L	334_T	0.562	0.25
248_F	303_D	0.562	0.25
63_P	152_L	0.561	0.25
368_P	388_Y	0.560	0.25
397_L	400_K	0.560	0.25
186_A	213_V	0.560	0.25
382_A	391_M	0.559	0.25
108_G	268_H	0.559	0.25
16_L	19_A	0.558	0.25
367_V	395_R	0.558	0.25
105_L	345_D	0.558	0.25
94_F	105_L	0.558	0.25
363_M	389_A	0.557	0.25
317_W	416_P	0.557	0.25
125_Y	249_F	0.556	0.25
197_L	391_M	0.556	0.25
107_A	159_V	0.555	0.25
336_N	340_S	0.554	0.25
325_T	328_R	0.553	0.25
194_E	361_Q	0.553	0.25
291_L	349_A	0.552	0.25
415_L	434_G	0.552	0.25
83_K	200_T	0.551	0.25
343_I	352_S	0.551	0.25
188_L	400_K	0.549	0.25
154_V	203_D	0.549	0.25
53_P	59_I	0.547	0.24
145_G	251_E	0.547	0.24
111_Y	122_G	0.546	0.24
289_P	327_V	0.546	0.24
85_T	91_S	0.545	0.24
415_L	433_R	0.545	0.24
292_K	334_T	0.544	0.24
298_Y	379_F	0.542	0.24
208_S	269_G	0.542	0.24
12_G	16_L	0.542	0.24
18_L	24_P	0.541	0.24
334_T	341_L	0.541	0.24
434_G	438_Y	0.541	0.24
291_L	302_I	0.540	0.24
363_M	376_R	0.540	0.24
370_S	391_M	0.540	0.24
432_A	447_Y	0.540	0.24
108_G	146_N	0.540	0.24
93_L	248_F	0.539	0.24
67_D	266_L	0.539	0.24
17_L	20_V	0.539	0.24
94_F	122_G	0.539	0.24
427_L	430_G	0.538	0.24
109_L	115_R	0.538	0.24
130_Q	373_E	0.537	0.24
133_V	152_L	0.534	0.24
108_G	159_V	0.534	0.24
167_L	185_S	0.533	0.24
47_V	149_A	0.533	0.24
313_Q	433_R	0.532	0.24
133_V	197_L	0.530	0.23
213_V	442_E	0.530	0.23
298_Y	450_S	0.528	0.23
48_S	96_D	0.527	0.23
68_Y	264_K	0.525	0.23
159_V	162_N	0.525	0.23
416_P	433_R	0.525	0.23
436_E	444_I	0.524	0.23
152_L	413_Q	0.523	0.23
236_D	400_K	0.522	0.23
334_T	386_M	0.522	0.23
229_V	259_A	0.521	0.23
390_H	433_R	0.521	0.23
90_I	203_D	0.518	0.23
15_A	99_N	0.518	0.23
155_A	245_L	0.518	0.23
411_V	427_L	0.515	0.23
313_Q	323_S	0.513	0.23
143_T	166_T	0.512	0.22
13_I	21_A	0.512	0.22
245_L	296_E	0.512	0.22
371_V	395_R	0.512	0.22
93_L	194_E	0.511	0.22
371_V	437_A	0.511	0.22
109_L	323_S	0.510	0.22
152_L	278_R	0.509	0.22
142_R	300_E	0.509	0.22
58_E	156_P	0.508	0.22
349_A	393_D	0.508	0.22
15_A	19_A	0.507	0.22
112_N	201_I	0.507	0.22
375_E	445_R	0.507	0.22
47_V	106_A	0.506	0.22
14_L	20_V	0.506	0.22
335_K	345_D	0.505	0.22
111_Y	291_L	0.505	0.22
12_G	15_A	0.503	0.22
295_F	322_T	0.503	0.22
391_M	443_N	0.502	0.22
154_V	197_L	0.501	0.22
49_T	84_V	0.501	0.22
16_L	149_A	0.501	0.22
322_T	339_Q	0.501	0.22
233_S	342_G	0.501	0.22
142_R	218_A	0.501	0.22
393_D	440_Y	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4p0gA	1	0.8224	100	0.497	Contact Map
4cfpA	1	0.5888	100	0.737	Contact Map
2yjpA	1	0.4653	100	0.801	Contact Map
4hjzA	1	0.3127	100	0.801	Contact Map
1xt8A	1	0.473	100	0.804	Contact Map
2ylnA	1	0.4498	100	0.807	Contact Map
1pb7A	1	0.4923	100	0.81	Contact Map
2ieeA	1	0.4672	100	0.811	Contact Map
3kbrA	4	0.4324	100	0.812	Contact Map
4ohnA	1	0.4595	100	0.815	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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