GREMLIN Database
SLT - Soluble lytic murein transglycosylase
UniProt: P0AGC3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10950
Length: 645 (595)
Sequences: 1389 (1121)
Seq/√Len: 46.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
361_R364_E7.4631.00
517_G525_M6.8511.00
357_L369_L5.4931.00
327_D330_G5.4101.00
606_I615_V5.0501.00
524_I556_I4.7521.00
585_R608_F4.5201.00
378_F603_V4.3411.00
357_L386_R3.9301.00
48_Q51_V3.7881.00
294_V297_E3.6731.00
516_V525_M3.5971.00
439_S442_E3.5771.00
560_Y583_P3.5571.00
114_D117_G3.5231.00
524_I529_A3.4891.00
144_Q147_E3.4251.00
504_Q621_Y3.3911.00
316_E320_R3.2771.00
352_Q356_L3.2671.00
332_N352_Q3.0451.00
320_R323_L3.0221.00
577_A615_V2.9911.00
497_Y576_S2.9101.00
498_A558_T2.8831.00
414_R430_E2.8221.00
585_R588_T2.8011.00
256_D259_N2.7891.00
34_R417_E2.7871.00
484_F502_A2.7061.00
350_Y354_D2.5981.00
87_N91_A2.5891.00
562_Q566_Q2.5181.00
319_V331_L2.5101.00
62_Y417_E2.4561.00
574_F590_L2.4181.00
519_S548_L2.4091.00
567_Q587_R2.4071.00
180_D183_A2.4031.00
106_V118_L2.3541.00
379_Y604_E2.2911.00
282_R289_L2.2911.00
513_K519_S2.2611.00
88_F92_N2.2181.00
356_L364_E2.1961.00
532_T560_Y2.1831.00
299_A302_R2.1821.00
365_A369_L2.1601.00
319_V323_L2.1521.00
317_R321_M2.1461.00
199_L203_L2.1311.00
153_K183_A2.1101.00
192_M200_V2.0821.00
368_I372_L2.0530.99
64_L67_Y2.0490.99
316_E319_V1.9970.99
336_A352_Q1.9870.99
317_R320_R1.9360.99
315_I319_V1.9010.99
228_V232_A1.9010.99
370_H389_E1.8930.99
504_Q617_N1.8880.99
502_A554_I1.8860.99
282_R286_A1.8770.99
373_M380_P1.8710.99
353_A369_L1.8660.99
287_W290_M1.8660.99
156_W187_R1.8610.99
135_Y139_K1.8550.99
568_F578_A1.8440.99
516_V519_S1.8400.99
34_R62_Y1.8330.99
576_S618_V1.8330.99
332_N359_R1.8310.99
532_T556_I1.8290.99
249_F253_A1.7940.99
136_Y148_A1.7670.98
282_R285_V1.7560.98
311_S317_R1.7510.98
332_N356_L1.7370.98
513_K516_V1.7170.98
71_R74_T1.7130.98
535_M563_Y1.7020.98
356_L361_R1.6880.98
366_K370_H1.6850.98
541_Y544_P1.6770.98
478_L629_M1.6670.98
464_I507_A1.6400.97
278_I287_W1.6370.97
500_A618_V1.6310.97
67_Y70_Y1.6290.97
314_L317_R1.6240.97
152_A169_L1.6230.97
51_V54_Q1.6220.97
133_C136_Y1.6210.97
43_A55_M1.6150.97
199_L202_V1.6010.97
278_I281_L1.5680.97
51_V55_M1.5650.97
282_R290_M1.5590.96
356_L368_I1.5550.96
315_I318_R1.5490.96
331_L335_L1.5440.96
188_I215_A1.5370.96
541_Y546_Q1.5360.96
128_T133_C1.5330.96
156_W602_F1.5330.96
110_A134_N1.5270.96
314_L320_R1.5210.96
213_T216_S1.5190.96
242_R246_A1.5070.96
319_V335_L1.5040.96
136_Y139_K1.5030.96
214_I218_I1.4960.96
43_A48_Q1.4910.95
347_E616_K1.4900.95
284_I287_W1.4800.95
138_A143_G1.4750.95
285_V288_R1.4730.95
42_Q45_D1.4710.95
538_I556_I1.4700.95
249_F252_V1.4690.95
354_D358_E1.4640.95
531_H563_Y1.4610.95
512_V519_S1.4410.94
448_R452_N1.4400.94
315_I321_M1.4350.94
349_R368_I1.4280.94
328_R331_L1.4220.94
319_V322_A1.4050.94
423_L426_T1.4040.94
385_Q391_Y1.3940.93
312_T315_I1.3910.93
311_S316_E1.3900.93
285_V290_M1.3860.93
56_M69_E1.3810.93
131_A139_K1.3800.93
65_Y71_R1.3780.93
498_A522_M1.3720.93
286_A290_M1.3530.92
302_R305_A1.3490.92
315_I320_R1.3490.92
59_L62_Y1.3490.92
357_L365_A1.3480.92
191_A199_L1.3390.92
543_S546_Q1.3340.92
247_V251_S1.3230.92
119_L138_A1.3220.91
76_D84_T1.3110.91
216_S219_I1.3110.91
162_Q170_F1.3110.91
573_I599_A1.3100.91
133_C138_A1.3060.91
480_Y510_P1.3060.91
128_T131_A1.2950.91
351_W354_D1.2940.91
483_L551_E1.2920.91
157_L183_A1.2820.90
214_I217_A1.2800.90
40_I47_R1.2780.90
312_T339_P1.2750.90
244_M252_V1.2740.90
133_C139_K1.2740.90
565_Y575_S1.2730.90
108_E112_R1.2680.90
67_Y71_R1.2680.90
243_Q247_V1.2590.89
281_L285_V1.2580.89
516_V527_G1.2550.89
69_E74_T1.2530.89
318_R324_G1.2460.89
227_T231_F1.2440.89
62_Y67_Y1.2440.89
83_V87_N1.2420.89
528_T560_Y1.2410.89
347_E604_E1.2400.89
302_R306_I1.2350.88
364_E367_E1.2350.88
242_R245_A1.2310.88
212_Q216_S1.2300.88
346_D372_L1.2230.88
157_L186_E1.2230.88
349_R371_Q1.2230.88
278_I282_R1.2230.88
513_K548_L1.2220.88
517_G527_G1.2220.88
44_W49_M1.2200.88
152_A156_W1.2130.88
307_M310_Q1.2100.87
477_P480_Y1.2090.87
493_I501_I1.2070.87
353_A368_I1.2050.87
290_M302_R1.2040.87
542_S546_Q1.2020.87
279_Q282_R1.1910.87
382_V602_F1.1870.86
133_C143_G1.1870.86
41_K44_W1.1860.86
332_N336_A1.1850.86
484_F488_T1.1810.86
301_W304_D1.1810.86
318_R322_A1.1790.86
351_W379_Y1.1780.86
282_R287_W1.1780.86
431_W450_A1.1730.86
298_Q301_W1.1680.85
213_T217_A1.1680.85
52_V56_M1.1680.85
479_A482_D1.1660.85
538_I578_A1.1660.85
338_L342_A1.1640.85
240_F243_Q1.1560.85
532_T559_S1.1530.85
38_A421_W1.1530.85
531_H535_M1.1490.84
70_Y74_T1.1470.84
245_A252_V1.1430.84
286_A302_R1.1420.84
541_Y547_L1.1420.84
116_R142_T1.1390.84
69_E91_A1.1380.84
161_S202_V1.1370.84
377_G380_P1.1360.84
40_I44_W1.1330.84
356_L359_R1.1330.84
303_D306_I1.1270.83
80_Q84_T1.1260.83
381_M621_Y1.1260.83
166_C202_V1.1250.83
568_F587_R1.1210.83
70_Y77_L1.1180.83
331_L601_A1.1170.83
584_G608_F1.1160.83
86_T90_R1.1080.82
473_E477_P1.1020.82
574_F586_V1.0990.82
89_V92_N1.0920.81
168_K172_V1.0920.81
478_L499_M1.0910.81
288_R292_N1.0870.81
524_I560_Y1.0830.81
578_A586_V1.0820.81
281_L290_M1.0770.80
52_V68_L1.0760.80
40_I68_L1.0750.80
299_A305_A1.0720.80
323_L601_A1.0690.80
368_I373_M1.0610.79
406_L412_M1.0600.79
281_L287_W1.0550.79
306_I310_Q1.0540.79
517_G526_P1.0500.79
419_M427_A1.0490.79
73_I88_F1.0460.78
287_W291_G1.0420.78
265_P269_Q1.0380.78
531_H567_Q1.0380.78
564_V578_A1.0360.78
352_Q355_L1.0350.78
565_Y570_N1.0350.78
311_S315_I1.0310.77
340_M343_K1.0300.77
321_M324_G1.0280.77
576_S619_L1.0280.77
196_N199_L1.0280.77
331_L355_L1.0270.77
251_S254_R1.0230.77
268_A271_Q1.0210.77
317_R323_L1.0200.77
498_A501_I1.0200.77
313_S318_R1.0190.77
118_L122_S1.0190.77
524_I532_T1.0150.76
37_Y62_Y1.0110.76
447_A459_S1.0050.76
282_R302_R1.0010.75
203_L208_P1.0000.75
286_A301_W0.9960.75
44_W56_M0.9960.75
298_Q302_R0.9950.75
36_R58_G0.9940.75
493_I498_A0.9920.75
594_A597_I0.9910.75
584_G587_R0.9900.74
339_P342_A0.9900.74
111_R327_D0.9890.74
247_V250_A0.9890.74
207_M211_Y0.9850.74
461_Q507_A0.9830.74
293_D302_R0.9810.74
290_M293_D0.9810.74
431_W462_A0.9800.74
37_Y59_L0.9800.74
479_A499_M0.9780.74
510_P550_P0.9770.73
482_D486_R0.9740.73
286_A293_D0.9700.73
416_R453_N0.9690.73
248_A252_V0.9680.73
66_P92_N0.9650.73
542_S547_L0.9640.72
243_Q251_S0.9610.72
311_S319_V0.9600.72
100_T104_R0.9580.72
312_T318_R0.9550.72
246_A250_A0.9540.72
381_M600_V0.9520.72
441_T444_A0.9510.71
55_M58_G0.9490.71
296_D301_W0.9460.71
158_T162_Q0.9450.71
527_G531_H0.9440.71
335_L338_L0.9430.71
282_R293_D0.9430.71
244_M247_V0.9390.70
613_G617_N0.9370.70
297_E300_K0.9370.70
279_Q283_D0.9370.70
232_A235_T0.9330.70
466_G602_F0.9320.70
532_T563_Y0.9320.70
302_R309_S0.9310.70
64_L70_Y0.9300.70
131_A135_Y0.9300.70
448_R451_F0.9280.70
64_L71_R0.9280.70
522_M557_G0.9270.69
281_L284_I0.9270.69
138_A142_T0.9260.69
306_I309_S0.9260.69
320_R324_G0.9250.69
298_Q303_D0.9250.69
137_Y141_N0.9240.69
241_T247_V0.9190.69
81_P84_T0.9180.69
399_P402_V0.9180.69
289_L293_D0.9160.69
536_F559_S0.9130.68
527_G584_G0.9120.68
500_A622_D0.9120.68
134_N137_Y0.9120.68
68_L384_A0.9110.68
283_D288_R0.9110.68
604_E612_R0.9080.68
370_H387_I0.9070.68
463_T466_G0.9040.68
525_M560_Y0.8990.67
204_A208_P0.8950.67
351_W355_L0.8930.67
546_Q549_D0.8920.66
267_L270_A0.8910.66
463_T474_E0.8900.66
69_E73_I0.8890.66
139_K151_G0.8870.66
378_F568_F0.8860.66
322_A338_L0.8810.65
179_Q183_A0.8800.65
348_W351_W0.8800.65
245_A253_A0.8740.65
37_Y591_G0.8720.65
586_V590_L0.8710.65
232_A236_G0.8710.65
36_R59_L0.8680.64
243_Q246_A0.8680.64
489_S530_T0.8650.64
381_M391_Y0.8600.64
379_Y616_K0.8580.63
354_D357_L0.8580.63
70_Y73_I0.8570.63
36_R55_M0.8570.63
289_L301_W0.8560.63
466_G507_A0.8540.63
137_Y144_Q0.8530.63
459_S474_E0.8520.63
165_A168_K0.8520.63
195_G222_A0.8510.63
321_M325_T0.8500.63
576_S585_R0.8490.63
409_G442_E0.8490.63
129_T133_C0.8430.62
156_W166_C0.8430.62
130_E165_A0.8410.62
49_M52_V0.8410.62
463_T469_W0.8410.62
485_K495_Q0.8400.62
94_T98_A0.8400.62
328_R335_L0.8390.62
62_Y66_P0.8370.61
137_Y140_W0.8360.61
312_T316_E0.8360.61
409_G412_M0.8360.61
559_S563_Y0.8350.61
558_T564_V0.8340.61
362_E366_K0.8310.61
202_V205_G0.8300.61
504_Q625_Y0.8300.61
497_Y561_L0.8290.61
335_L343_K0.8260.60
406_L415_V0.8250.60
386_R600_V0.8250.60
516_V550_P0.8210.60
515_P530_T0.8200.60
303_D309_S0.8200.60
223_N228_V0.8180.60
156_W159_G0.8170.60
59_L68_L0.8170.60
65_Y70_Y0.8170.60
106_V122_S0.8170.60
528_T583_P0.8160.60
313_S323_L0.8140.59
244_M248_A0.8120.59
65_Y75_D0.8090.59
369_L386_R0.8080.59
292_N302_R0.8070.59
101_L188_I0.8070.59
501_I618_V0.8060.59
277_Q281_L0.8060.59
85_V101_L0.8050.58
622_D626_R0.8040.58
461_Q509_N0.8010.58
160_K191_A0.8000.58
148_A151_G0.8000.58
108_E114_D0.7970.58
282_R288_R0.7950.58
151_G163_P0.7940.57
450_A462_A0.7930.57
188_I207_M0.7930.57
40_I56_M0.7930.57
519_S547_L0.7920.57
166_C348_W0.7920.57
40_I48_Q0.7910.57
564_V583_P0.7900.57
285_V299_A0.7890.57
354_D369_L0.7880.57
460_V463_T0.7880.57
133_C140_W0.7830.56
335_L355_L0.7830.56
538_I555_N0.7830.56
118_L131_A0.7790.56
284_I290_M0.7760.56
313_S317_R0.7750.56
44_W68_L0.7750.56
299_A303_D0.7740.55
313_S316_E0.7730.55
37_Y41_K0.7720.55
217_A235_T0.7710.55
321_M617_N0.7710.55
134_N139_K0.7710.55
300_K303_D0.7690.55
63_P477_P0.7690.55
454_Q459_S0.7670.55
378_F382_V0.7660.55
102_Q106_V0.7660.55
72_Q75_D0.7640.55
317_R324_G0.7640.55
517_G528_T0.7640.55
139_K144_Q0.7630.54
421_W426_T0.7630.54
187_R192_M0.7620.54
440_K444_A0.7620.54
38_A41_K0.7620.54
65_Y69_E0.7600.54
617_N620_A0.7590.54
459_S462_A0.7570.54
279_Q290_M0.7550.54
565_Y572_R0.7550.54
314_L322_A0.7540.54
245_A250_A0.7520.53
372_L616_K0.7520.53
221_L228_V0.7510.53
501_I576_S0.7500.53
211_Y217_A0.7480.53
48_Q59_L0.7480.53
398_A403_D0.7470.53
361_R570_N0.7470.53
245_A251_S0.7460.53
449_Y453_N0.7440.53
351_W504_Q0.7410.52
264_I435_V0.7400.52
96_P159_G0.7400.52
462_A465_A0.7390.52
584_G588_T0.7380.52
67_Y76_D0.7380.52
359_R362_E0.7370.52
242_R252_V0.7370.52
525_M528_T0.7360.52
200_V203_L0.7350.52
328_R601_A0.7350.52
312_T317_R0.7340.52
589_W606_I0.7340.52
93_P180_D0.7320.51
319_V338_L0.7310.51
136_Y151_G0.7300.51
488_T600_V0.7290.51
303_D307_M0.7280.51
44_W52_V0.7270.51
524_I547_L0.7270.51
519_S525_M0.7270.51
266_S269_Q0.7260.51
283_D286_A0.7260.51
302_R449_Y0.7260.51
55_M500_A0.7240.51
454_Q460_V0.7240.51
41_K45_D0.7210.50
415_V450_A0.7210.50
411_E430_E0.7200.50
446_L457_D0.7190.50
613_G620_A0.7190.50
131_A136_Y0.7180.50
504_Q613_G0.7170.50
328_R338_L0.7170.50
542_S545_G0.7170.50
146_E150_Q0.7160.50
154_E530_T0.7160.50
442_E445_Q0.7160.50
83_V89_V0.7160.50
522_M577_A0.7140.50
329_R359_R0.7140.50
411_E414_R0.7140.50
64_L69_E0.7140.50
406_L409_G0.7120.49
305_A309_S0.7120.49
505_E580_N0.7100.49
63_P70_Y0.7090.49
152_A173_W0.7080.49
185_L189_R0.7070.49
312_T319_V0.7060.49
128_T135_Y0.7030.49
304_D308_R0.7010.48
229_L232_A0.7010.48
240_F245_A0.6990.48
274_N277_Q0.6970.48
522_M558_T0.6940.48
149_W153_K0.6920.47
119_L142_T0.6890.47
229_L235_T0.6870.47
384_A583_P0.6870.47
278_I288_R0.6870.47
210_D213_T0.6870.47
514_S518_A0.6860.47
479_A484_F0.6860.47
479_A502_A0.6860.47
528_T582_G0.6850.47
69_E152_A0.6850.47
100_T426_T0.6820.46
45_D423_L0.6820.46
406_L445_Q0.6820.46
124_E487_Y0.6820.46
298_Q306_I0.6820.46
225_P230_T0.6810.46
278_I285_V0.6800.46
282_R301_W0.6800.46
400_Q403_D0.6800.46
287_W293_D0.6770.46
488_T494_P0.6770.46
219_I222_A0.6750.46
166_C173_W0.6750.46
36_R39_Q0.6740.46
38_A42_Q0.6700.45
544_P547_L0.6700.45
429_S616_K0.6690.45
130_E133_C0.6690.45
524_I553_N0.6690.45
380_P617_N0.6680.45
89_V118_L0.6670.45
151_G156_W0.6660.45
264_I285_V0.6660.45
494_P622_D0.6660.45
445_Q500_A0.6650.45
422_N561_L0.6650.45
403_D441_T0.6640.45
371_Q374_Q0.6640.45
290_M301_W0.6640.45
484_F554_I0.6630.45
67_Y414_R0.6620.45
286_A299_A0.6590.44
245_A249_F0.6590.44
139_K147_E0.6580.44
314_L319_V0.6560.44
444_A460_V0.6560.44
381_M624_Y0.6550.44
244_M251_S0.6550.44
133_C137_Y0.6550.44
302_R310_Q0.6540.44
493_I588_T0.6540.44
132_Q154_E0.6540.44
264_I568_F0.6540.44
569_G590_L0.6530.44
219_I289_L0.6520.44
372_L383_A0.6520.44
521_L557_G0.6520.44
130_E140_W0.6510.43
449_Y602_F0.6510.43
508_W621_Y0.6510.43
225_P229_L0.6500.43
572_R619_L0.6500.43
289_L292_N0.6490.43
73_I101_L0.6490.43
501_I554_I0.6480.43
59_L534_K0.6480.43
463_T470_D0.6480.43
135_Y138_A0.6470.43
280_E283_D0.6460.43
190_L194_A0.6450.43
568_F583_P0.6450.43
238_T241_T0.6430.43
153_K407_T0.6430.43
315_I322_A0.6420.43
279_Q284_I0.6420.43
289_L298_Q0.6420.43
87_N363_A0.6410.42
435_V462_A0.6400.42
496_S629_M0.6400.42
201_T208_P0.6390.42
320_R431_W0.6370.42
340_M529_A0.6370.42
171_S174_R0.6360.42
339_P343_K0.6360.42
60_K65_Y0.6350.42
529_A599_A0.6350.42
248_A254_R0.6330.42
349_R372_L0.6320.42
35_S54_Q0.6320.42
369_L373_M0.6320.42
484_F499_M0.6310.42
565_Y616_K0.6310.42
249_F256_D0.6300.41
601_A620_A0.6300.41
507_A621_Y0.6300.41
430_E620_A0.6290.41
462_A466_G0.6290.41
312_T342_A0.6280.41
330_G333_T0.6280.41
194_A578_A0.6260.41
65_Y68_L0.6260.41
72_Q76_D0.6250.41
350_Y355_L0.6240.41
319_V334_W0.6240.41
354_D382_V0.6230.41
354_D386_R0.6220.41
553_N607_P0.6220.41
481_N485_K0.6220.41
200_V550_P0.6220.41
316_E322_A0.6210.41
458_L558_T0.6210.41
129_T346_D0.6210.41
517_G535_M0.6210.41
185_L613_G0.6200.40
210_D214_I0.6200.40
615_V619_L0.6190.40
257_A619_L0.6190.40
70_Y76_D0.6190.40
440_K443_Q0.6160.40
335_L348_W0.6150.40
71_R75_D0.6150.40
96_P126_P0.6130.40
496_S499_M0.6130.40
533_V538_I0.6130.40
316_E321_M0.6120.40
403_D454_Q0.6120.40
203_L207_M0.6120.40
311_S320_R0.6110.40
159_G163_P0.6110.40
376_R381_M0.6110.40
528_T533_V0.6110.40
502_A507_A0.6090.39
521_L615_V0.6090.39
258_E294_V0.6070.39
579_Y614_Y0.6070.39
331_L338_L0.6070.39
197_T200_V0.6070.39
501_I516_V0.6060.39
90_R420_Y0.6060.39
49_M72_Q0.6050.39
140_W145_S0.6050.39
456_W459_S0.6040.39
378_F458_L0.6040.39
320_R348_W0.6040.39
214_I219_I0.6030.39
366_K387_I0.6010.39
119_L123_P0.6000.39
415_V430_E0.6000.39
152_A179_Q0.6000.39
213_T220_S0.5990.39
56_M488_T0.5980.38
104_R107_N0.5980.38
136_Y152_A0.5970.38
366_K482_D0.5950.38
561_L617_N0.5950.38
259_N333_T0.5950.38
367_E486_R0.5940.38
554_I575_S0.5930.38
91_A465_A0.5930.38
480_Y484_F0.5930.38
417_E477_P0.5930.38
86_T102_Q0.5910.38
338_L343_K0.5910.38
347_E617_N0.5910.38
136_Y169_L0.5900.38
68_L72_Q0.5900.38
42_Q48_Q0.5890.38
102_Q124_E0.5890.38
191_A203_L0.5890.38
285_V293_D0.5890.38
279_Q287_W0.5880.37
143_G148_A0.5860.37
35_S38_A0.5860.37
243_Q250_A0.5860.37
531_H618_V0.5860.37
343_K460_V0.5840.37
606_I618_V0.5840.37
220_S228_V0.5840.37
313_S324_G0.5840.37
442_E446_L0.5830.37
343_K348_W0.5810.37
101_L373_M0.5810.37
103_S127_G0.5790.37
61_D65_Y0.5790.37
138_A141_N0.5780.37
352_Q420_Y0.5780.37
210_D219_I0.5780.37
351_W577_A0.5780.37
484_F600_V0.5770.36
211_Y214_I0.5770.36
39_Q46_N0.5770.36
293_D603_V0.5760.36
265_P524_I0.5760.36
536_F555_N0.5760.36
50_D441_T0.5750.36
108_E111_R0.5740.36
378_F585_R0.5740.36
457_D608_F0.5730.36
403_D549_D0.5710.36
394_K535_M0.5700.36
451_F456_W0.5700.36
211_Y216_S0.5680.36
132_Q136_Y0.5670.36
376_R621_Y0.5670.36
67_Y74_T0.5660.35
220_S353_A0.5660.35
580_N614_Y0.5660.35
150_Q178_K0.5650.35
267_L271_Q0.5650.35
365_A388_G0.5640.35
66_P71_R0.5630.35
290_M299_A0.5630.35
317_R322_A0.5620.35
264_I298_Q0.5620.35
284_I609_S0.5610.35
39_Q529_A0.5610.35
34_R37_Y0.5600.35
466_G470_D0.5600.35
335_L552_T0.5590.35
293_D378_F0.5590.35
138_A148_A0.5580.35
446_L449_Y0.5580.35
370_H373_M0.5570.35
47_R108_E0.5570.35
139_K142_T0.5560.35
192_M382_V0.5560.35
282_R291_G0.5560.35
587_R590_L0.5550.35
62_Y65_Y0.5550.35
105_F438_K0.5550.35
585_R607_P0.5540.34
67_Y97_P0.5530.34
216_S220_S0.5530.34
251_S256_D0.5530.34
34_R48_Q0.5520.34
297_E302_R0.5520.34
602_F624_Y0.5510.34
40_I418_L0.5500.34
446_L450_A0.5490.34
529_A532_T0.5480.34
528_T557_G0.5480.34
411_E434_L0.5480.34
63_P66_P0.5480.34
619_L629_M0.5480.34
385_Q618_V0.5480.34
105_F121_F0.5470.34
595_G602_F0.5470.34
82_A105_F0.5470.34
53_E72_Q0.5460.34
284_I603_V0.5460.34
234_T238_T0.5460.34
567_Q608_F0.5450.34
129_T155_L0.5440.34
105_F109_L0.5430.33
33_Q59_L0.5420.33
54_Q413_A0.5420.33
118_L134_N0.5420.33
318_R338_L0.5420.33
339_P361_R0.5410.33
381_M476_F0.5410.33
177_G414_R0.5400.33
305_A308_R0.5400.33
372_L617_N0.5390.33
248_A602_F0.5390.33
52_V71_R0.5380.33
463_T602_F0.5380.33
168_K264_I0.5380.33
432_A458_L0.5370.33
287_W301_W0.5370.33
529_A541_Y0.5360.33
563_Y567_Q0.5350.33
233_R554_I0.5350.33
314_L318_R0.5340.33
89_V121_F0.5340.33
111_R337_R0.5340.33
81_P294_V0.5340.33
282_R299_A0.5340.33
357_L366_K0.5330.33
146_E237_A0.5330.33
378_F385_Q0.5330.33
543_S547_L0.5330.33
580_N610_E0.5320.32
312_T473_E0.5320.32
74_T77_L0.5310.32
370_H551_E0.5310.32
250_A253_A0.5310.32
129_T493_I0.5300.32
42_Q363_A0.5290.32
97_P556_I0.5270.32
495_Q524_I0.5270.32
290_M295_T0.5270.32
585_R612_R0.5260.32
577_A606_I0.5250.32
43_A51_V0.5240.32
620_A624_Y0.5240.32
290_M294_V0.5240.32
243_Q253_A0.5240.32
187_R602_F0.5240.32
213_T219_I0.5240.32
347_E561_L0.5230.32
494_P512_V0.5220.32
506_S564_V0.5210.32
455_W460_V0.5210.32
305_A310_Q0.5210.32
62_Y71_R0.5200.31
264_I268_A0.5200.31
264_I598_D0.5200.31
303_D318_R0.5180.31
346_D377_G0.5180.31
483_L554_I0.5180.31
350_Y503_R0.5180.31
526_P560_Y0.5160.31
210_D218_I0.5150.31
521_L550_P0.5150.31
512_V604_E0.5150.31
437_S568_F0.5130.31
283_D299_A0.5130.31
235_T239_D0.5130.31
201_T216_S0.5120.31
246_A251_S0.5110.31
283_D290_M0.5110.31
513_K551_E0.5110.31
48_Q272_Q0.5100.31
292_N295_T0.5100.31
245_A257_A0.5100.31
523_Q580_N0.5100.31
41_K71_R0.5090.31
155_L162_Q0.5080.30
521_L553_N0.5080.30
44_W218_I0.5080.30
82_A112_R0.5080.30
446_L502_A0.5080.30
228_V231_F0.5070.30
43_A568_F0.5070.30
464_I469_W0.5060.30
132_Q138_A0.5060.30
420_Y570_N0.5050.30
348_W372_L0.5050.30
122_S135_Y0.5040.30
476_F480_Y0.5040.30
521_L554_I0.5040.30
560_Y564_V0.5030.30
296_D300_K0.5030.30
558_T568_F0.5020.30
177_G370_H0.5020.30
283_D287_W0.5020.30
300_K527_G0.5020.30
581_A589_W0.5010.30
189_R193_K0.5010.30
296_D530_T0.5010.30
505_E579_Y0.5010.30
65_Y554_I0.5010.30
488_T598_D0.5010.30
382_V600_V0.5010.30
246_A297_E0.5000.30
369_L572_R0.5000.30
284_I288_R0.5000.30
73_I92_N0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qsaA 1 0.9581 100 0.22 Contact Map
4hjzA 1 0.2527 100 0.724 Contact Map
4cfpA 1 0.4295 100 0.729 Contact Map
4p0gA 1 0.5845 100 0.753 Contact Map
1gbsA 1 0.2667 100 0.768 Contact Map
4g9sA 1 0.2698 100 0.774 Contact Map
3gxrA 1 0.2636 100 0.774 Contact Map
3w6bA 1 0.2326 100 0.776 Contact Map
3bkhA 1 0.3457 100 0.79 Contact Map
4hpeA 1 0.2264 100 0.815 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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