SERB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

SERB - Phosphoserine phosphatase

UniProt:	P0AGB0	Sequences: MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRSRVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKLRLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10945
Length:	322 (279)
Sequences:	1276 (766)
Seq/√Len:	45.9

ECOLI - SERB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
155_T	245_D	5.357	1.00
146_R	160_S	5.152	1.00
229_E	238_N	5.095	1.00
194_E	221_T	4.274	1.00
247_Q	251_K	4.136	1.00
277_L	295_V	3.888	1.00
174_Q	178_E	3.764	1.00
229_E	240_I	3.484	1.00
145_E	149_R	3.258	1.00
166_K	238_N	2.930	1.00
287_I	311_V	2.875	1.00
187_T	217_K	2.874	1.00
246_A	278_P	2.859	1.00
254_T	282_A	2.850	1.00
143_V	164_T	2.825	1.00
201_A	256_L	2.807	1.00
169_D	234_K	2.785	1.00
132_K	137_G	2.782	1.00
152_L	156_A	2.658	1.00
177_R	213_Y	2.544	1.00
296_N	304_R	2.514	1.00
142_E	146_R	2.512	1.00
224_V	255_R	2.506	1.00
123_Q	183_M	2.502	1.00
122_I	126_C	2.442	1.00
211_A	223_V	2.341	1.00
168_A	172_I	2.321	1.00
212_E	215_R	2.307	1.00
115_M	270_I	2.300	1.00
173_L	209_F	2.249	1.00
124_I	181_P	2.182	1.00
183_M	289_Y	2.166	1.00
170_A	174_Q	2.159	1.00
199_K	222_A	2.136	1.00
215_R	223_V	2.127	1.00
145_E	289_Y	2.086	1.00
248_Y	252_T	2.070	1.00
224_V	252_T	2.063	0.99
170_A	230_I	1.999	0.99
253_L	269_A	1.944	0.99
229_E	236_T	1.924	0.99
255_R	259_E	1.892	0.99
146_R	149_R	1.845	0.99
193_L	315_L	1.843	0.99
156_A	160_S	1.835	0.99
175_Q	179_N	1.785	0.99
155_T	159_R	1.763	0.98
194_E	219_R	1.758	0.98
159_R	241_G	1.732	0.98
257_A	267_T	1.730	0.98
212_E	223_V	1.708	0.98
155_T	243_I	1.706	0.98
146_R	151_E	1.685	0.98
131_A	140_V	1.660	0.98
136_T	164_T	1.659	0.98
99_A	314_I	1.651	0.97
153_D	156_A	1.643	0.97
71_V	74_Y	1.612	0.97
123_Q	184_P	1.606	0.97
190_V	200_V	1.597	0.97
139_M	143_V	1.558	0.96
159_R	238_N	1.524	0.96
269_A	279_M	1.522	0.96
295_V	298_K	1.518	0.96
121_A	186_L	1.511	0.96
306_A	310_G	1.500	0.96
133_L	175_Q	1.497	0.96
139_M	142_E	1.463	0.95
288_A	291_A	1.456	0.95
224_V	248_Y	1.435	0.94
170_A	233_G	1.434	0.94
194_E	200_V	1.419	0.94
152_L	160_S	1.410	0.94
257_A	264_L	1.405	0.94
128_D	137_G	1.404	0.94
294_K	298_K	1.360	0.93
231_M	238_N	1.327	0.92
113_L	193_L	1.319	0.91
166_K	234_K	1.317	0.91
133_L	179_N	1.295	0.91
158_L	235_F	1.279	0.90
270_I	311_V	1.279	0.90
193_L	198_W	1.255	0.89
257_A	262_I	1.250	0.89
139_M	164_T	1.236	0.88
41_L	101_L	1.233	0.88
112_L	267_T	1.222	0.88
136_T	139_M	1.200	0.87
70_C	76_V	1.197	0.87
213_Y	217_K	1.179	0.86
285_L	301_V	1.172	0.86
281_K	298_K	1.168	0.85
59_L	66_V	1.160	0.85
280_I	286_G	1.150	0.84
48_D	51_R	1.147	0.84
130_I	168_A	1.147	0.84
202_I	220_L	1.111	0.82
263_P	266_Q	1.109	0.82
253_L	267_T	1.102	0.82
174_Q	209_F	1.086	0.81
222_A	259_E	1.075	0.80
242_D	251_K	1.066	0.80
201_A	222_A	1.066	0.80
121_A	218_L	1.051	0.79
187_T	214_L	1.049	0.79
70_C	73_D	1.040	0.78
112_L	194_E	1.036	0.78
60_G	65_I	1.025	0.77
149_R	293_P	1.025	0.77
210_F	290_H	1.023	0.77
124_I	129_E	1.019	0.76
277_L	298_K	1.017	0.76
280_I	295_V	1.016	0.76
134_A	137_G	1.011	0.76
296_N	302_T	1.011	0.76
124_I	180_L	1.011	0.76
182_L	217_K	1.011	0.76
153_D	245_D	1.002	0.75
290_H	306_A	0.997	0.75
129_E	132_K	0.997	0.75
132_K	138_E	0.991	0.74
231_M	240_I	0.988	0.74
173_L	235_F	0.976	0.73
159_R	243_I	0.973	0.73
82_S	86_R	0.970	0.73
170_A	209_F	0.964	0.72
186_L	308_L	0.958	0.72
255_R	258_Q	0.957	0.72
84_T	88_T	0.952	0.71
208_T	227_E	0.952	0.71
144_T	154_F	0.946	0.71
264_L	282_A	0.943	0.71
79_L	82_S	0.942	0.71
86_R	89_R	0.942	0.71
227_E	240_I	0.934	0.70
191_L	218_L	0.934	0.70
182_L	214_L	0.924	0.69
158_L	202_I	0.920	0.69
252_T	256_L	0.916	0.68
125_E	144_T	0.915	0.68
71_V	76_V	0.912	0.68
67_A	70_C	0.910	0.68
125_E	148_M	0.907	0.68
264_L	267_T	0.902	0.67
144_T	148_M	0.884	0.66
199_K	221_T	0.884	0.66
218_L	250_A	0.873	0.65
303_I	310_G	0.872	0.65
118_D	126_C	0.867	0.64
199_K	260_Y	0.865	0.64
55_Y	227_E	0.861	0.64
257_A	260_Y	0.859	0.63
110_P	198_W	0.859	0.63
229_E	241_G	0.849	0.63
169_D	172_I	0.846	0.62
125_E	207_F	0.840	0.62
124_I	246_A	0.839	0.62
222_A	256_L	0.838	0.62
250_A	278_P	0.837	0.61
52_L	58_K	0.821	0.60
197_G	284_G	0.821	0.60
152_L	196_L	0.813	0.59
119_S	144_T	0.807	0.59
68_A	71_V	0.806	0.58
59_L	62_A	0.805	0.58
158_L	162_V	0.800	0.58
127_I	225_A	0.796	0.58
142_E	182_L	0.791	0.57
268_V	309_M	0.789	0.57
145_E	290_H	0.787	0.57
126_C	129_E	0.784	0.56
149_R	289_Y	0.782	0.56
250_A	254_T	0.782	0.56
139_M	160_S	0.776	0.56
307_D	310_G	0.775	0.56
198_W	303_I	0.774	0.55
57_S	61_A	0.773	0.55
136_T	140_V	0.772	0.55
216_D	259_E	0.771	0.55
154_F	204_S	0.767	0.55
313_C	316_S	0.766	0.55
125_E	205_G	0.765	0.55
173_L	177_R	0.765	0.55
156_A	244_V	0.763	0.54
73_D	77_I	0.760	0.54
256_L	267_T	0.756	0.54
148_M	205_G	0.755	0.54
262_I	267_T	0.755	0.54
126_C	210_F	0.753	0.53
121_A	309_M	0.750	0.53
163_A	238_N	0.748	0.53
130_I	173_L	0.748	0.53
250_A	282_A	0.745	0.53
274_A	279_M	0.742	0.52
247_Q	250_A	0.742	0.52
125_E	161_R	0.742	0.52
149_R	218_L	0.740	0.52
148_M	207_F	0.740	0.52
85_A	139_M	0.740	0.52
177_R	209_F	0.738	0.52
254_T	258_Q	0.735	0.52
117_M	307_D	0.731	0.51
111_G	266_Q	0.730	0.51
144_T	207_F	0.729	0.51
121_A	126_C	0.729	0.51
147_A	207_F	0.727	0.51
125_E	147_A	0.727	0.51
171_N	234_K	0.726	0.51
289_Y	312_F	0.719	0.50
128_D	290_H	0.719	0.50
150_G	274_A	0.717	0.50
54_Q	61_A	0.712	0.49
247_Q	278_P	0.711	0.49
41_L	71_V	0.710	0.49
209_F	213_Y	0.708	0.49
235_F	294_K	0.707	0.49
117_M	210_F	0.705	0.49
288_A	304_R	0.703	0.48
125_E	154_F	0.702	0.48
99_A	301_V	0.702	0.48
270_I	287_I	0.701	0.48
244_V	248_Y	0.701	0.48
97_D	310_G	0.700	0.48
256_L	259_E	0.697	0.48
144_T	161_R	0.696	0.48
208_T	211_A	0.691	0.47
131_A	204_S	0.691	0.47
127_I	269_A	0.690	0.47
170_A	231_M	0.689	0.47
107_L	111_G	0.689	0.47
288_A	299_A	0.688	0.47
119_S	207_F	0.683	0.46
250_A	281_K	0.683	0.46
212_E	227_E	0.681	0.46
222_A	260_Y	0.676	0.46
277_L	293_P	0.676	0.46
119_S	125_E	0.675	0.46
49_K	53_T	0.675	0.46
112_L	262_I	0.673	0.46
156_A	241_G	0.672	0.45
225_A	266_Q	0.672	0.45
176_V	211_A	0.672	0.45
123_Q	290_H	0.672	0.45
121_A	127_I	0.671	0.45
127_I	140_V	0.670	0.45
202_I	223_V	0.670	0.45
220_L	223_V	0.669	0.45
233_G	236_T	0.666	0.45
198_W	315_L	0.660	0.44
144_T	292_K	0.652	0.43
115_M	121_A	0.648	0.43
70_C	314_I	0.643	0.43
114_V	196_L	0.642	0.43
288_A	292_K	0.642	0.43
260_Y	264_L	0.641	0.42
173_L	218_L	0.641	0.42
273_G	292_K	0.640	0.42
169_D	175_Q	0.639	0.42
127_I	228_L	0.637	0.42
115_M	189_L	0.635	0.42
74_Y	77_I	0.634	0.42
52_L	62_A	0.634	0.42
144_T	205_G	0.633	0.42
148_M	206_G	0.632	0.42
295_V	300_E	0.625	0.41
224_V	256_L	0.624	0.41
125_E	273_G	0.619	0.40
144_T	147_A	0.619	0.40
41_L	44_G	0.618	0.40
191_L	194_E	0.616	0.40
117_M	128_D	0.612	0.40
269_A	280_I	0.611	0.40
148_M	161_R	0.611	0.40
89_R	94_A	0.611	0.40
67_A	76_V	0.611	0.40
280_I	299_A	0.609	0.39
133_L	176_V	0.608	0.39
123_Q	181_P	0.608	0.39
148_M	154_F	0.608	0.39
87_A	100_P	0.607	0.39
117_M	211_A	0.607	0.39
175_Q	178_E	0.601	0.39
131_A	239_V	0.600	0.39
53_T	287_I	0.599	0.38
117_M	290_H	0.599	0.38
66_V	287_I	0.599	0.38
158_L	203_A	0.599	0.38
267_T	311_V	0.598	0.38
56_Q	59_L	0.598	0.38
125_E	206_G	0.598	0.38
193_L	286_G	0.597	0.38
58_K	65_I	0.594	0.38
201_A	210_F	0.594	0.38
200_V	203_A	0.591	0.38
131_A	154_F	0.591	0.38
306_A	309_M	0.590	0.38
267_T	278_P	0.590	0.38
117_M	129_E	0.590	0.38
161_R	206_G	0.589	0.38
89_R	93_E	0.589	0.38
242_D	312_F	0.588	0.37
117_M	246_A	0.588	0.37
71_V	197_G	0.587	0.37
108_R	312_F	0.587	0.37
68_A	77_I	0.585	0.37
245_D	248_Y	0.585	0.37
121_A	157_S	0.584	0.37
70_C	75_Q	0.583	0.37
203_A	248_Y	0.582	0.37
146_R	152_L	0.580	0.37
85_A	174_Q	0.580	0.37
151_E	293_P	0.578	0.37
119_S	154_F	0.577	0.36
256_L	260_Y	0.577	0.36
70_C	74_Y	0.577	0.36
254_T	264_L	0.576	0.36
54_Q	212_E	0.576	0.36
72_E	77_I	0.575	0.36
140_V	228_L	0.573	0.36
152_L	274_A	0.572	0.36
41_L	55_Y	0.572	0.36
283_A	311_V	0.571	0.36
230_I	233_G	0.569	0.36
144_T	273_G	0.569	0.36
90_L	94_A	0.568	0.36
296_N	310_G	0.567	0.36
157_S	293_P	0.567	0.36
125_E	275_N	0.566	0.35
98_V	250_A	0.564	0.35
130_I	280_I	0.564	0.35
101_L	313_C	0.561	0.35
229_E	232_D	0.561	0.35
101_L	115_M	0.558	0.35
138_E	142_E	0.557	0.35
246_A	251_K	0.557	0.35
189_L	308_L	0.556	0.35
161_R	207_F	0.554	0.34
277_L	294_K	0.553	0.34
138_E	172_I	0.552	0.34
234_K	238_N	0.552	0.34
58_K	62_A	0.551	0.34
275_N	292_K	0.550	0.34
188_Q	309_M	0.550	0.34
139_M	163_A	0.549	0.34
183_M	290_H	0.548	0.34
111_G	260_Y	0.548	0.34
244_V	252_T	0.548	0.34
138_E	164_T	0.547	0.34
223_V	244_V	0.545	0.34
147_A	205_G	0.544	0.33
154_F	225_A	0.543	0.33
46_G	50_Q	0.543	0.33
136_T	203_A	0.542	0.33
290_H	307_D	0.542	0.33
47_L	298_K	0.541	0.33
119_S	292_K	0.541	0.33
125_E	274_A	0.541	0.33
40_W	43_Y	0.541	0.33
82_S	89_R	0.539	0.33
71_V	189_L	0.539	0.33
121_A	220_L	0.537	0.33
218_L	233_G	0.537	0.33
296_N	309_M	0.537	0.33
45_R	73_D	0.536	0.33
109_T	196_L	0.535	0.33
242_D	248_Y	0.534	0.33
123_Q	137_G	0.533	0.33
180_L	200_V	0.532	0.32
156_A	159_R	0.532	0.32
45_R	184_P	0.532	0.32
303_I	306_A	0.532	0.32
148_M	273_G	0.532	0.32
151_E	291_A	0.531	0.32
157_S	309_M	0.531	0.32
257_A	269_A	0.530	0.32
47_L	56_Q	0.530	0.32
163_A	166_K	0.528	0.32
119_S	131_A	0.528	0.32
119_S	148_M	0.528	0.32
173_L	210_F	0.526	0.32
218_L	314_I	0.526	0.32
114_V	223_V	0.525	0.32
86_R	93_E	0.524	0.32
44_G	139_M	0.524	0.32
125_E	292_K	0.523	0.32
144_T	157_S	0.523	0.32
203_A	252_T	0.521	0.32
155_T	247_Q	0.520	0.31
129_E	210_F	0.520	0.31
57_S	60_G	0.519	0.31
55_Y	73_D	0.518	0.31
164_T	221_T	0.518	0.31
40_W	52_L	0.515	0.31
203_A	244_V	0.513	0.31
60_G	69_W	0.513	0.31
128_D	141_A	0.513	0.31
134_A	303_I	0.511	0.31
143_V	211_A	0.511	0.31
178_E	191_L	0.511	0.31
257_A	282_A	0.510	0.31
190_V	307_D	0.509	0.30
150_G	161_R	0.507	0.30
154_F	207_F	0.507	0.30
206_G	226_N	0.507	0.30
131_A	144_T	0.507	0.30
226_N	271_G	0.506	0.30
176_V	229_E	0.506	0.30
177_R	309_M	0.506	0.30
133_L	181_P	0.504	0.30
206_G	273_G	0.504	0.30
125_E	150_G	0.504	0.30
79_L	259_E	0.503	0.30
90_L	95_Q	0.502	0.30
235_F	290_H	0.502	0.30
150_G	279_M	0.501	0.30
62_A	86_R	0.500	0.30
61_A	179_N	0.500	0.30
121_A	202_I	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ezeA	1	0.8602	100	0.539	Contact Map
3p96A	2	1	100	0.574	Contact Map
3m1yA	2	0.6491	100	0.63	Contact Map
1l7mA	1	0.6522	100	0.646	Contact Map
3n28A	1	0.9503	100	0.662	Contact Map
3fvvA	2	0.6304	100	0.701	Contact Map
1rkuA	2	0.6211	100	0.704	Contact Map
4gxtA	1	0.764	100	0.71	Contact Map
4as2A	4	0.7267	100	0.712	Contact Map
1y8aA	1	0.6429	100	0.716	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0092 seconds.