GREMLIN Database
RS14 - 30S ribosomal protein S14
UniProt: P0AG59 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10913
Length: 101 (100)
Sequences: 1902 (806)
Seq/√Len: 80.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_A11_V3.6171.00
61_R71_H3.3251.00
10_E14_V3.2841.00
62_N73_F2.9321.00
64_C67_T2.9311.00
17_A60_Q2.7681.00
74_L84_V2.5361.00
14_V60_Q2.4401.00
11_V14_V2.2341.00
51_L55_S2.2171.00
33_D36_A2.2151.00
16_L55_S2.1991.00
10_E60_Q2.1781.00
93_I96_L1.9611.00
84_V96_L1.9001.00
4_Q7_K1.8831.00
20_Y55_S1.8781.00
88_A96_L1.7981.00
4_Q8_A1.7501.00
31_I45_V1.7441.00
21_F25_A1.6991.00
26_E30_I1.6551.00
83_K86_E1.6131.00
77_F96_L1.5991.00
29_A32_S1.5721.00
86_E90_R1.4370.99
30_I44_A1.3900.99
67_T83_K1.3600.99
6_M10_E1.3100.98
64_C83_K1.2890.98
87_A92_E1.2600.98
36_A41_R1.2500.98
32_S45_V1.2320.97
6_M9_R1.2260.97
18_D21_F1.1960.97
46_L50_T1.1870.97
47_K51_L1.1670.96
23_K26_E1.1630.96
9_R12_K1.1520.96
29_A33_D1.1330.96
22_A26_E1.0890.95
65_R78_G1.0860.95
20_Y51_L1.0810.95
37_S40_D1.0190.93
24_R55_S0.9940.92
14_V18_D0.9890.91
28_K48_L0.9730.91
80_S83_K0.9430.89
13_R54_D0.9390.89
30_I36_A0.9240.88
33_D41_R0.8990.87
9_R13_R0.8880.86
31_I48_L0.8700.85
38_D42_W0.8650.85
6_M70_P0.8630.85
10_E61_R0.8620.85
79_L87_A0.8500.84
54_D59_R0.8270.82
15_A19_K0.8230.82
3_K6_M0.8210.82
43_N47_K0.8160.81
89_M93_I0.8130.81
88_A93_I0.8100.81
10_E13_R0.8090.81
84_V93_I0.8070.81
12_K16_L0.7780.78
52_P55_S0.7720.78
66_Q79_L0.7700.77
51_L57_P0.7660.77
53_R58_S0.7630.77
28_K32_S0.7620.77
27_L94_P0.7610.77
31_I44_A0.7560.76
77_F84_V0.7550.76
62_N75_R0.7500.76
22_A25_A0.7470.75
87_A90_R0.7430.75
61_R70_P0.7360.74
5_S70_P0.7230.73
25_A29_A0.7080.71
24_R56_S0.7010.71
30_I47_K0.6960.70
13_R16_L0.6950.70
9_R49_Q0.6950.70
32_S41_R0.6930.70
61_R72_G0.6830.69
14_V71_H0.6820.68
40_D43_N0.6790.68
47_K50_T0.6770.68
75_R84_V0.6750.68
79_L83_K0.6690.67
83_K87_A0.6690.67
13_R59_R0.6670.67
24_R31_I0.6640.66
34_V38_D0.6590.66
16_L54_D0.6570.66
16_L56_S0.6530.65
44_A76_K0.6470.64
31_I49_Q0.6460.64
20_Y52_P0.6430.64
22_A27_L0.6410.64
66_Q83_K0.6400.64
84_V88_A0.6390.63
45_V55_S0.6390.63
14_V62_N0.6350.63
26_E44_A0.6310.62
6_M89_M0.6270.62
67_T80_S0.6260.62
89_M99_A0.6230.61
62_N72_G0.6140.60
84_V89_M0.6080.60
18_D22_A0.5950.58
68_G91_G0.5920.58
46_L93_I0.5900.57
78_G100_S0.5860.57
31_I41_R0.5820.56
10_E17_A0.5700.55
46_L49_Q0.5620.54
70_P82_I0.5610.54
10_E65_R0.5580.53
89_M92_E0.5580.53
53_R59_R0.5560.53
53_R69_R0.5500.52
18_D26_E0.5470.52
18_D43_N0.5450.52
61_R73_F0.5400.51
45_V74_L0.5370.51
42_W45_V0.5350.50
34_V45_V0.5350.50
10_E63_R0.5340.50
66_Q71_H0.5340.50
34_V37_S0.5340.50
82_I86_E0.5320.50
30_I40_D0.5310.50
49_Q58_S0.5260.49
13_R23_K0.5250.49
27_L98_K0.5250.49
67_T86_E0.5250.49
12_K54_D0.5200.48
45_V49_Q0.5190.48
59_R69_R0.5190.48
65_R97_K0.5180.48
23_K90_R0.5160.48
87_A93_I0.5150.48
24_R57_P0.5090.47
83_K89_M0.5080.47
47_K54_D0.5040.46
34_V41_R0.5000.46
9_R54_D0.5000.46
30_I33_D0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bbnN 1 0.9802 100 0.107 Contact Map
4tp8N 1 0.9505 100 0.114 Contact Map
5aj3N 1 0.9802 100 0.184 Contact Map
4rb5N 1 0.5941 99.9 0.471 Contact Map
4w23d 1 0.495 99.6 0.618 Contact Map
3j60d 1 0.4554 99.5 0.626 Contact Map
4ujpe 1 0.505 99.5 0.637 Contact Map
3j7aT 1 0.4554 99.5 0.639 Contact Map
3zey8 1 0.396 99.4 0.651 Contact Map
4bpeN 1 0.5149 99.4 0.658 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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