GREMLIN Database
RL30 - 50S ribosomal protein L30
UniProt: P0AG51 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10888
Length: 59 (57)
Sequences: 1477 (695)
Seq/√Len: 92.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
40_D45_R3.5491.00
13_A24_L2.5991.00
49_N52_S2.5501.00
8_T35_T2.4241.00
20_H53_F2.2701.00
18_P22_A2.2401.00
19_K50_A2.0971.00
9_Q24_L2.0521.00
6_K58_E1.9861.00
30_R34_H1.9821.00
6_K37_E1.7641.00
24_L51_V1.7271.00
10_T56_K1.7181.00
4_T37_E1.5511.00
38_R44_I1.5001.00
7_I38_R1.3880.99
8_T56_K1.3590.99
4_T39_E1.2310.98
8_T58_E1.2280.98
22_A26_G1.1910.98
13_A25_L1.1850.98
22_A25_L1.1200.97
26_G43_A1.1120.97
5_I48_I1.0710.96
9_Q13_A1.0620.96
23_T47_M1.0570.96
23_T50_A1.0530.96
26_G47_M1.0500.96
17_L20_H1.0310.95
5_I45_R1.0120.95
13_A21_K0.9670.93
26_G38_R0.9430.92
44_I47_M0.9390.92
31_R34_H0.9110.91
5_I40_D0.9110.91
9_Q34_H0.8960.90
25_L30_R0.8490.88
39_E44_I0.8330.87
20_H50_A0.8110.85
17_L21_K0.7860.83
3_K39_E0.7760.83
40_D48_I0.7750.82
18_P21_K0.7570.81
11_R16_R0.7480.80
9_Q32_I0.7360.79
6_K35_T0.7360.79
17_L50_A0.7330.79
16_R20_H0.7250.78
48_I55_V0.6930.75
29_L32_I0.6910.75
18_P25_L0.6740.73
19_K23_T0.6740.73
39_E43_A0.6640.72
23_T38_R0.6560.71
17_L53_F0.6530.70
5_I37_E0.6380.69
27_L38_R0.6290.68
7_I44_I0.6230.67
13_A16_R0.6150.66
29_L36_V0.6120.65
21_K25_L0.6100.65
3_K40_D0.6080.65
23_T26_G0.6000.64
17_L23_T0.5960.63
5_I44_I0.5930.63
14_I21_K0.5910.63
41_T44_I0.5810.61
7_I36_V0.5730.60
7_I55_V0.5720.60
42_P55_V0.5670.60
16_R52_S0.5600.59
16_R54_M0.5550.58
11_R15_G0.5400.56
38_R47_M0.5360.55
35_T56_K0.5330.55
16_R21_K0.5150.53
13_A34_H0.5130.52
26_G41_T0.5120.52
11_R30_R0.5090.52
19_K47_M0.5060.51
23_T44_I0.5050.51
12_S16_R0.5050.51
15_G21_K0.5020.51
34_H55_V0.5020.51
3_K43_A0.5000.50
8_T33_G0.5000.50
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vw4U 1 0.9661 99.9 0.197 Contact Map
4tp9Z 1 0.0339 99.8 0.21 Contact Map
3j7yZ 1 1 99.8 0.21 Contact Map
1bxyA 1 0.9831 99.8 0.215 Contact Map
3j3vY 1 0.9492 99.8 0.243 Contact Map
2zjrW 1 0.9322 99.8 0.248 Contact Map
3j21Y 1 0.9831 99.8 0.294 Contact Map
1vq8W 1 0.9492 99.7 0.334 Contact Map
4w20F 1 1 99.7 0.342 Contact Map
1vx75 1 1 99.7 0.346 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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