GREMLIN Database
RL17 - 50S ribosomal protein L17
UniProt: P0AG44 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10878
Length: 127 (113)
Sequences: 2368 (1080)
Seq/√Len: 101.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_R43_E2.9461.00
38_L111_A2.8921.00
32_E78_K2.7921.00
33_I114_E2.7091.00
44_L113_I2.5631.00
30_R72_D2.4281.00
52_I115_L2.3111.00
16_H23_N2.2861.00
29_V48_V2.0741.00
25_A48_V2.0521.00
96_R114_E2.0031.00
66_A80_F1.9821.00
28_L48_V1.9451.00
29_V115_L1.9401.00
77_A81_N1.8571.00
38_L99_K1.7991.00
32_E86_R1.7721.00
67_F76_V1.6851.00
61_A65_L1.6491.00
35_K112_Y1.6071.00
54_L66_A1.5911.00
59_S62_N1.5631.00
58_D62_N1.5551.00
81_N85_P1.5111.00
20_M40_K1.4951.00
90_R116_V1.4891.00
14_S18_Q1.4691.00
23_N27_S1.4471.00
25_A47_V1.4461.00
20_M24_M1.3720.99
65_L69_R1.3430.99
35_K100_C1.3300.99
33_I112_Y1.3200.99
54_L65_L1.3110.99
95_T113_I1.3040.99
43_E46_R1.2870.99
12_R17_R1.2700.99
25_A51_L1.2440.99
100_C112_Y1.2400.99
78_K82_E1.2240.99
60_V64_R1.2040.99
36_T41_A1.2020.99
55_A84_G1.1960.99
16_H20_M1.1920.99
12_R40_K1.1820.98
97_I111_A1.1320.98
10_L43_E1.1310.98
102_F107_N1.1280.98
26_G75_I1.1210.98
55_A79_L1.1140.98
57_T62_N1.1000.98
26_G71_R1.0980.97
29_V75_I1.0840.97
22_R26_G1.0650.97
32_E83_L1.0580.97
70_T75_I1.0470.97
13_N16_H1.0450.97
22_R71_R1.0400.97
51_L69_R1.0310.96
62_N65_L1.0300.96
20_M27_S1.0280.96
38_L109_P1.0080.96
65_L68_A1.0080.96
100_C110_M1.0030.96
63_R80_F0.9850.95
49_E97_I0.9820.95
35_K110_M0.9800.95
67_F77_A0.9680.95
46_R50_P0.9660.95
17_R43_E0.9640.95
102_F109_P0.9350.94
51_L79_L0.8960.92
85_P88_A0.8930.92
12_R20_M0.8790.92
27_S30_R0.8730.91
46_R49_E0.8660.91
21_F47_V0.8580.91
50_P54_L0.8570.90
26_G72_D0.8520.90
66_A76_V0.8510.90
45_R113_I0.8380.89
45_R49_E0.8230.89
37_T108_A0.8210.89
26_G70_T0.8020.87
29_V83_L0.8010.87
79_L83_L0.8010.87
52_I87_F0.8010.87
28_L113_I0.7970.87
57_T61_A0.7970.87
32_E87_F0.7970.87
48_V95_T0.7950.87
27_S31_H0.7950.87
101_G109_P0.7910.87
45_R97_I0.7890.86
21_F24_M0.7730.85
60_V67_F0.7720.85
9_Q13_N0.7650.85
87_F115_L0.7640.85
21_F44_L0.7580.84
30_R75_I0.7530.84
25_A69_R0.7350.82
82_E85_P0.7340.82
90_R117_D0.7100.80
54_L80_F0.7090.80
47_V69_R0.7080.80
24_M44_L0.7080.80
58_D63_R0.7070.80
86_R117_D0.7040.80
7_G46_R0.7000.79
103_R110_M0.6980.79
25_A44_L0.6910.78
24_M27_S0.6790.77
104_A110_M0.6730.76
63_R76_V0.6700.76
53_T94_Y0.6680.76
56_K91_A0.6660.76
83_L87_F0.6620.75
66_A79_L0.6610.75
32_E82_E0.6570.75
39_P109_P0.6560.75
101_G110_M0.6480.74
18_Q22_R0.6370.72
8_R39_P0.6350.72
105_G115_L0.6350.72
30_R73_N0.6310.72
87_F117_D0.6290.71
55_A66_A0.6170.70
67_F73_N0.6150.70
23_N49_E0.6130.70
30_R74_E0.6080.69
28_L44_L0.6080.69
19_A71_R0.6010.68
103_R106_D0.6000.68
44_L47_V0.5990.68
45_R95_T0.5970.68
107_N110_M0.5930.67
60_V63_R0.5890.67
53_T92_G0.5850.66
58_D66_A0.5840.66
10_L20_M0.5810.65
5_K43_E0.5790.65
78_K87_F0.5780.65
103_R108_A0.5770.65
16_H40_K0.5770.65
51_L89_S0.5730.64
31_H40_K0.5730.64
9_Q104_A0.5710.64
95_T115_L0.5690.64
11_N39_P0.5590.62
53_T56_K0.5550.62
29_V79_L0.5530.62
63_R67_F0.5530.62
16_H19_A0.5530.62
20_M34_I0.5450.61
67_F70_T0.5410.60
73_N77_A0.5390.60
39_P108_A0.5380.60
42_K97_I0.5340.59
67_F71_R0.5320.59
13_N40_K0.5290.58
25_A49_E0.5290.58
76_V80_F0.5110.56
36_T40_K0.5100.56
74_E78_K0.5090.55
96_R116_V0.5050.55
7_G21_F0.5050.55
17_R20_M0.5050.55
26_G67_F0.5020.54
22_R51_L0.5010.54
18_Q69_R0.5000.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tp9N 1 0.9449 100 0.03 Contact Map
3bboP 1 0.9055 100 0.036 Contact Map
1gd8A 1 0.8189 100 0.042 Contact Map
3j7yO 1 1 100 0.045 Contact Map
2zjrK 1 0.8898 100 0.048 Contact Map
1vw4L 1 0.9843 100 0.088 Contact Map
3j3wN 1 0.8819 100 0.105 Contact Map
3h0dA 2 0.6929 6.7 0.951 Contact Map
2bkmA 1 0.4252 6.3 0.952 Contact Map
4yfkF 1 0 4.8 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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