GREMLIN Database
RELA - GTP pyrophosphokinase
UniProt: P0AG20 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10835
Length: 744 (704)
Sequences: 3419 (1960)
Seq/√Len: 73.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
96_R101_K7.5821.00
429_Y437_H5.4451.00
512_L546_I5.2461.00
444_I449_V4.7991.00
445_G459_D4.6621.00
726_L738_A4.5211.00
246_K284_E4.3731.00
35_L98_S4.3441.00
425_L482_Y4.2561.00
85_A92_E4.1121.00
71_M150_V4.0901.00
285_R288_D3.8421.00
284_E341_K3.7901.00
483_V492_I3.7341.00
161_R197_E3.7301.00
32_C77_R3.7211.00
248_E341_K3.6411.00
282_V341_K3.6261.00
239_E242_A3.5141.00
74_D102_S3.3291.00
676_R682_D3.2541.00
33_E76_L3.1461.00
168_E171_R3.1281.00
236_L296_V3.0831.00
176_K180_N3.0291.00
536_F545_A3.0021.00
250_Y344_H2.8781.00
231_E330_G2.8691.00
42_C45_Q2.8461.00
21_I33_E2.8421.00
505_I544_A2.8341.00
163_V205_Y2.8151.00
435_V465_T2.7731.00
444_I453_Y2.7611.00
268_L273_L2.7291.00
207_H210_E2.7111.00
620_E636_A2.6961.00
213_R217_L2.6921.00
237_R241_K2.6361.00
39_W90_V2.6131.00
214_I256_I2.5991.00
454_Q484_T2.5861.00
671_V729_L2.5451.00
217_L270_F2.5121.00
34_C38_T2.4891.00
168_E172_V2.4621.00
633_V655_A2.4321.00
410_T416_V2.4281.00
85_A95_L2.4051.00
92_E108_H2.3711.00
668_V713_T2.3651.00
509_R543_L2.3241.00
669_V726_L2.3051.00
94_V97_E2.2761.00
697_V712_M2.2751.00
284_E288_D2.2501.00
485_T488_G2.2471.00
455_L461_I2.2471.00
63_V76_L2.2431.00
66_L75_T2.2001.00
673_A679_L2.1711.00
166_A174_A2.1481.00
531_L539_V2.1381.00
227_H231_E2.1161.00
238_A242_A2.1161.00
106_L151_I2.1021.00
32_C35_L2.1011.00
105_N144_D2.0891.00
505_I540_D2.0781.00
292_A295_I2.0591.00
443_K462_E2.0451.00
221_R224_D2.0441.00
538_D541_E2.0371.00
626_T632_S2.0251.00
622_V641_L2.0091.00
171_R205_Y1.9631.00
714_I725_V1.9611.00
234_G238_A1.9611.00
228_Y328_G1.9511.00
233_V237_R1.9371.00
692_V721_V1.9341.00
341_K345_E1.9191.00
38_T41_Y1.9091.00
281_I292_A1.8951.00
210_E213_R1.8891.00
234_G237_R1.8721.00
287_Q291_A1.8641.00
50_P166_A1.8601.00
163_V175_A1.8311.00
232_F334_V1.8261.00
160_L198_L1.8181.00
453_Y456_Q1.8131.00
422_S485_T1.7961.00
71_M75_T1.7941.00
283_A292_A1.7911.00
93_D96_R1.7881.00
163_V174_A1.7811.00
424_P442_A1.7781.00
73_I77_R1.7711.00
288_D291_A1.7691.00
32_C74_D1.7571.00
408_V455_L1.7431.00
222_R253_P1.7411.00
66_L79_A1.7331.00
92_E96_R1.7291.00
536_F542_L1.7241.00
229_I251_G1.7091.00
453_Y459_D1.6981.00
92_E104_V1.6971.00
433_S437_H1.6971.00
96_R104_V1.6971.00
20_W68_T1.6911.00
175_A202_C1.6901.00
600_E654_D1.6901.00
226_E230_E1.6891.00
239_E299_H1.6811.00
421_G454_Q1.6811.00
32_C103_V1.6741.00
212_K215_A1.6701.00
500_D503_K1.6681.00
83_P87_A1.6621.00
539_V543_L1.6571.00
671_V712_M1.6531.00
675_D708_A1.6511.00
218_L256_I1.6411.00
77_R103_V1.6391.00
369_G372_D1.6371.00
196_W255_H1.6301.00
78_A106_L1.6261.00
85_A108_H1.6070.99
93_D97_E1.6070.99
24_L70_S1.5880.99
512_L543_L1.5870.99
40_A56_L1.5790.99
220_E332_K1.5690.99
92_E105_N1.5630.99
687_L712_M1.5560.99
87_A111_R1.5490.99
228_Y329_P1.5430.99
196_W222_R1.5330.99
85_A104_V1.5260.99
501_R541_E1.5250.99
501_R505_I1.5080.99
425_L483_V1.5010.99
383_W387_M1.5010.99
179_T257_Y1.5000.99
676_R679_L1.5000.99
31_S35_L1.5000.99
257_Y261_R1.4910.99
728_K731_Q1.4810.99
94_V98_S1.4810.99
91_S94_V1.4640.99
424_P444_I1.4600.99
544_A547_G1.4490.99
85_A111_R1.4460.99
230_E234_G1.4440.99
203_F207_H1.4440.99
494_A498_K1.4420.99
230_E233_V1.4330.99
203_F256_I1.4170.99
160_L201_Y1.4150.99
235_H300_Y1.4130.99
39_W98_S1.4090.99
38_T42_C1.4060.99
690_E728_K1.4020.99
320_Q346_D1.3950.98
306_E325_V1.3950.98
240_M292_A1.3950.98
65_I161_R1.3920.98
222_R226_E1.3920.98
680_L697_V1.3810.98
83_P86_D1.3810.98
232_F279_V1.3800.98
216_K220_E1.3660.98
595_G599_V1.3650.98
87_A159_H1.3630.98
158_A162_E1.3620.98
159_H162_E1.3600.98
240_M247_A1.3490.98
405_R417_D1.3390.98
297_H324_T1.3340.98
15_F19_K1.3270.98
31_S34_C1.3220.98
66_L76_L1.3200.98
241_K247_A1.3190.98
90_V94_V1.3190.98
687_L694_V1.3140.98
86_D111_R1.3050.98
21_I25_G1.3020.98
670_R711_D1.3010.98
204_R215_A1.2970.98
233_V249_V1.2940.98
622_V652_I1.2910.97
442_A449_V1.2880.97
296_V336_I1.2830.97
215_A256_I1.2820.97
167_P170_E1.2800.97
354_H357_Y1.2740.97
430_H487_R1.2700.97
86_D159_H1.2680.97
686_I725_V1.2640.97
676_R734_D1.2610.97
43_L94_V1.2590.97
39_W43_L1.2540.97
196_W253_P1.2500.97
719_L723_G1.2500.97
151_I187_N1.2470.97
87_A112_D1.2440.97
473_R496_F1.2330.97
672_V737_D1.2330.97
641_L652_I1.2320.97
296_V326_V1.2280.97
37_E41_Y1.2260.97
679_L708_A1.2190.96
528_K532_P1.2160.96
673_A708_A1.2160.96
486_S490_S1.2120.96
169_D173_L1.2110.96
449_V453_Y1.2080.96
101_K105_N1.2040.96
610_A632_S1.2030.96
623_G653_V1.1950.96
49_H159_H1.1940.96
49_H87_A1.1930.96
686_I690_E1.1890.96
44_Q87_A1.1870.96
41_Y45_Q1.1830.96
44_Q83_P1.1760.96
624_F651_R1.1760.96
198_L202_C1.1730.96
406_V457_M1.1720.96
699_S710_I1.1710.95
293_L338_I1.1620.95
283_A288_D1.1600.95
683_I710_I1.1600.95
495_W499_Q1.1580.95
49_H158_A1.1530.95
687_L692_V1.1520.95
211_Y215_A1.1500.95
66_L110_V1.1460.95
422_S484_T1.1440.95
90_V98_S1.1390.95
166_A170_E1.1380.95
49_H55_L1.1380.95
375_A378_R1.1320.95
424_P449_V1.1310.95
43_L90_V1.1300.95
522_S525_E1.1270.94
596_R599_V1.1270.94
56_L59_G1.1240.94
22_A30_K1.1230.94
378_R381_I1.1210.94
252_R358_K1.1210.94
45_Q48_G1.1160.94
203_F210_E1.1150.94
212_K216_K1.1130.94
687_L714_I1.1130.94
427_F431_I1.1120.94
58_R158_A1.1120.94
669_V714_I1.1100.94
44_Q55_L1.1100.94
49_H83_P1.1050.94
155_E159_H1.1010.94
529_H532_P1.1000.94
49_H52_A1.0990.94
160_L163_V1.0990.94
693_N715_E1.0980.94
233_V279_V1.0920.93
700_R711_D1.0910.93
59_G159_H1.0890.93
42_C46_T1.0890.93
237_R248_E1.0880.93
666_S715_E1.0860.93
672_V709_T1.0850.93
44_Q49_H1.0820.93
83_P159_H1.0770.93
44_Q86_D1.0760.93
217_L271_D1.0760.93
679_L682_D1.0750.93
352_A358_K1.0720.93
20_W64_E1.0720.93
21_I67_S1.0710.93
434_D437_H1.0700.93
597_V621_I1.0600.92
64_E68_T1.0590.92
243_E295_I1.0580.92
670_R739_R1.0550.92
29_Q73_I1.0540.92
66_L71_M1.0540.92
424_P455_L1.0520.92
466_Q469_P1.0510.92
406_V453_Y1.0460.92
87_A158_A1.0450.92
239_E243_E1.0370.92
677_S691_K1.0350.91
21_I24_L1.0340.91
620_E635_R1.0300.91
470_N495_W1.0290.91
666_S713_T1.0270.91
669_V712_M1.0270.91
87_A162_E1.0260.91
664_G715_E1.0250.91
61_E64_E1.0240.91
668_V711_D1.0240.91
327_L331_G1.0230.91
82_F178_C1.0220.91
23_S422_S1.0200.91
149_V185_L1.0200.91
679_L732_V1.0190.91
423_T482_Y1.0180.91
288_D292_A1.0160.91
690_E724_R1.0150.91
395_D398_R1.0150.91
59_G82_F1.0110.91
44_Q59_G1.0100.90
726_L730_N1.0090.90
278_A354_H1.0060.90
55_L87_A1.0040.90
111_R159_H1.0030.90
43_L89_V1.0020.90
634_H638_C1.0020.90
83_P111_R0.9960.90
112_D159_H0.9960.90
59_G87_A0.9930.90
294_G297_H0.9930.90
439_C451_F0.9930.90
438_R468_Q0.9900.90
290_Y294_G0.9870.89
441_G464_I0.9860.89
82_F159_H0.9850.89
678_G693_N0.9840.89
247_A292_A0.9820.89
172_V206_L0.9820.89
407_Y417_D0.9820.89
377_L383_W0.9770.89
342_Q345_E0.9760.89
86_D162_E0.9750.89
228_Y232_F0.9730.89
354_H358_K0.9730.89
160_L178_C0.9720.89
55_L83_P0.9720.89
262_K357_Y0.9700.89
86_D158_A0.9690.89
626_T640_Q0.9690.89
44_Q159_H0.9680.89
218_L276_V0.9670.88
83_P88_N0.9670.88
613_C638_C0.9670.88
82_F86_D0.9660.88
681_R688_A0.9650.88
141_A406_V0.9640.88
239_E295_I0.9630.88
542_L551_I0.9630.88
109_G137_R0.9620.88
49_H58_R0.9570.88
112_D155_E0.9570.88
170_E173_L0.9550.88
437_H495_W0.9540.88
25_G73_I0.9530.88
49_H82_F0.9510.88
670_R709_T0.9500.88
262_K358_K0.9480.87
302_H312_A0.9440.87
545_A551_I0.9420.87
15_F34_C0.9420.87
696_G713_T0.9420.87
25_G28_S0.9380.87
59_G158_A0.9370.87
59_G86_D0.9370.87
95_L104_V0.9350.87
679_L734_D0.9350.87
345_E349_L0.9340.87
263_M270_F0.9320.87
44_Q58_R0.9300.86
673_A735_V0.9300.86
416_V430_H0.9280.86
49_H59_G0.9270.86
262_K335_E0.9260.86
335_E354_H0.9260.86
17_P22_A0.9260.86
260_W264_Q0.9240.86
236_L336_I0.9220.86
47_Q86_D0.9220.86
682_D732_V0.9220.86
44_Q47_Q0.9210.86
78_A151_I0.9210.86
65_I197_E0.9200.86
15_F18_E0.9180.86
62_M155_E0.9130.85
48_G54_L0.9110.85
55_L159_H0.9100.85
142_M146_F0.9090.85
516_L557_V0.9070.85
16_D20_W0.9050.85
17_P20_W0.9030.85
352_A357_Y0.9020.85
370_H374_I0.9010.85
16_D64_E0.9010.85
58_R62_M0.9000.85
262_K354_H0.8980.84
231_E234_G0.8970.84
63_V79_A0.8960.84
136_R329_P0.8960.84
252_R357_Y0.8930.84
613_C634_H0.8920.84
598_V656_V0.8890.84
697_V701_S0.8890.84
616_I667_L0.8880.84
49_H162_E0.8860.84
410_T431_I0.8850.84
218_L270_F0.8850.84
609_I616_I0.8850.84
685_T689_N0.8840.84
235_H299_H0.8830.83
232_F300_Y0.8800.83
55_L158_A0.8800.83
166_A173_L0.8770.83
82_F158_A0.8730.83
483_V488_G0.8720.83
51_D165_D0.8700.83
74_D77_R0.8700.83
19_K23_S0.8690.82
732_V735_V0.8660.82
254_K354_H0.8650.82
82_F87_A0.8630.82
59_G83_P0.8620.82
132_V488_G0.8620.82
662_S671_V0.8610.82
329_P680_L0.8610.82
344_H348_E0.8600.82
675_D701_S0.8580.82
58_R159_H0.8580.82
49_H86_D0.8570.82
86_D155_E0.8570.82
21_I26_I0.8560.82
81_L103_V0.8540.81
254_K262_K0.8520.81
473_R500_D0.8520.81
111_R162_E0.8510.81
44_Q111_R0.8510.81
58_R82_F0.8490.81
320_Q640_Q0.8490.81
47_Q87_A0.8480.81
290_Y293_L0.8470.81
442_A463_I0.8410.80
88_N159_H0.8400.80
677_S693_N0.8390.80
290_Y297_H0.8380.80
224_D227_H0.8380.80
49_H111_R0.8380.80
695_L715_E0.8380.80
286_L298_T0.8360.80
514_D517_E0.8360.80
235_H239_E0.8350.80
678_G684_T0.8350.80
55_L88_N0.8330.80
126_S129_S0.8320.80
252_R278_A0.8310.80
644_L652_I0.8310.80
443_K464_I0.8280.79
599_V655_A0.8280.79
83_P178_C0.8270.79
170_E174_A0.8260.79
44_Q162_E0.8230.79
44_Q82_F0.8220.79
74_D103_V0.8210.79
722_L726_L0.8210.79
152_K159_H0.8210.79
297_H307_F0.8200.79
335_E357_Y0.8180.78
612_C634_H0.8180.78
204_R212_K0.8140.78
425_L439_C0.8140.78
55_L58_R0.8130.78
641_L645_R0.8100.78
220_E377_L0.8100.78
44_Q158_A0.8100.78
35_L77_R0.8100.78
59_G88_N0.8090.78
138_M142_M0.8090.78
718_N721_V0.8090.78
631_I655_A0.8080.78
33_E73_I0.8080.78
676_R732_V0.8070.78
47_Q88_N0.8070.78
47_Q55_L0.8060.77
111_R158_A0.8060.77
602_V605_L0.8060.77
308_D325_V0.8050.77
135_V300_Y0.8050.77
55_L86_D0.8030.77
88_N162_E0.8030.77
681_R685_T0.8020.77
335_E358_K0.8020.77
19_K22_A0.8010.77
241_K246_K0.7990.77
79_A151_I0.7980.77
519_L557_V0.7980.77
52_A58_R0.7960.77
58_R162_E0.7940.76
87_A155_E0.7930.76
541_E544_A0.7920.76
280_R337_Q0.7920.76
83_P112_D0.7910.76
59_G62_M0.7900.76
55_L59_G0.7890.76
676_R683_I0.7880.76
262_K278_A0.7870.76
88_N111_R0.7860.76
261_R265_K0.7850.76
51_D87_A0.7840.75
240_M249_V0.7840.75
622_V636_A0.7830.75
666_S695_L0.7810.75
44_Q51_D0.7810.75
303_L333_T0.7810.75
157_I194_L0.7800.75
58_R155_E0.7790.75
433_S495_W0.7780.75
109_G148_C0.7780.75
537_N541_E0.7770.75
692_V725_V0.7760.75
240_M245_V0.7740.75
335_E352_A0.7730.74
82_F155_E0.7720.74
673_A710_I0.7720.74
515_E518_H0.7710.74
701_S708_A0.7700.74
65_I154_A0.7700.74
254_K335_E0.7690.74
28_S31_S0.7690.74
252_R354_H0.7660.74
30_K34_C0.7650.74
134_N409_F0.7640.74
87_A170_E0.7600.73
180_N398_R0.7600.73
718_N722_L0.7600.73
370_H373_R0.7590.73
675_D706_Q0.7570.73
612_C638_C0.7560.73
611_R614_Q0.7550.73
228_Y330_G0.7540.73
66_L641_L0.7540.73
371_E378_R0.7530.73
82_F111_R0.7530.73
49_H88_N0.7520.72
424_P454_Q0.7510.72
55_L82_F0.7510.72
164_K204_R0.7510.72
225_R253_P0.7500.72
86_D109_G0.7500.72
280_R354_H0.7500.72
209_T212_K0.7490.72
88_N112_D0.7480.72
433_S491_K0.7480.72
437_H496_F0.7480.72
236_L439_C0.7470.72
221_R225_R0.7470.72
58_R112_D0.7470.72
112_D162_E0.7470.72
252_R335_E0.7460.72
278_A358_K0.7450.72
108_H137_R0.7450.72
18_E30_K0.7430.72
236_L279_V0.7430.72
172_V336_I0.7430.72
171_R443_K0.7420.71
262_K352_A0.7410.71
281_I726_L0.7410.71
44_Q88_N0.7390.71
231_E235_H0.7390.71
159_H170_E0.7380.71
155_E158_A0.7380.71
686_I728_K0.7370.71
29_Q32_C0.7370.71
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278_A357_Y0.7350.71
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46_T54_L0.7330.70
58_R83_P0.7320.70
356_K378_R0.7320.70
258_S358_K0.7310.70
379_K383_W0.7300.70
137_R148_C0.7290.70
83_P107_I0.7290.70
114_A174_A0.7290.70
83_P158_A0.7280.70
254_K357_Y0.7260.70
614_Q668_V0.7240.70
506_L510_Q0.7240.70
530_L556_M0.7220.69
528_K539_V0.7220.69
21_I30_K0.7210.69
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112_D158_A0.7200.69
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534_Y551_I0.7190.69
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97_E101_K0.7150.69
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626_T630_G0.7120.68
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516_L543_L0.7070.68
82_F162_E0.7060.68
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226_E253_P0.7000.67
376_W383_W0.7000.67
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139_L143_V0.7000.67
280_R357_Y0.6980.67
92_E95_L0.6980.67
241_K560_L0.6980.67
515_E519_L0.6980.67
501_R540_D0.6980.67
498_K502_D0.6970.67
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608_H629_R0.6960.67
58_R87_A0.6920.66
263_M310_Y0.6920.66
490_S494_A0.6910.66
26_I29_Q0.6900.66
58_R84_L0.6900.66
39_W95_L0.6890.66
482_Y487_R0.6880.66
59_G162_E0.6880.66
433_S674_N0.6870.66
204_R222_R0.6850.65
431_I434_D0.6850.65
86_D112_D0.6850.65
425_L444_I0.6840.65
545_A550_D0.6810.65
683_I687_L0.6810.65
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57_W61_E0.6790.65
26_I30_K0.6790.65
140_L402_F0.6790.65
393_M398_R0.6790.65
508_G547_G0.6790.65
566_K569_A0.6790.65
216_K219_H0.6780.64
227_H230_E0.6770.64
434_D438_R0.6770.64
136_R471_P0.6740.64
633_V653_V0.6740.64
131_Q138_M0.6720.64
18_E21_I0.6710.64
25_G493_H0.6690.63
183_A198_L0.6670.63
27_T31_S0.6670.63
44_Q112_D0.6670.63
294_G298_T0.6670.63
723_G727_G0.6660.63
409_F414_D0.6660.63
96_R105_N0.6650.63
163_V171_R0.6650.63
431_I492_I0.6650.63
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513_D523_L0.6640.63
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214_I217_L0.6620.63
83_P170_E0.6610.63
278_A336_I0.6610.63
600_E656_V0.6610.63
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275_D335_E0.6590.62
210_E260_W0.6570.62
427_F463_I0.6570.62
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262_K280_R0.6560.62
686_I732_V0.6550.62
275_D354_H0.6550.62
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110_V113_M0.6540.62
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51_D58_R0.6510.61
438_R466_Q0.6500.61
83_P162_E0.6500.61
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280_R335_E0.6470.61
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318_G341_K0.6420.60
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406_V421_G0.6340.59
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606_M631_I0.6290.59
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252_R262_K0.6280.59
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44_Q107_I0.6270.58
681_R684_T0.6270.58
231_E453_Y0.6250.58
506_L509_R0.6250.58
155_E178_C0.6240.58
44_Q170_E0.6240.58
364_G725_V0.6240.58
635_R679_L0.6220.58
624_F644_L0.6220.58
32_C38_T0.6210.58
444_I461_I0.6210.58
505_I667_L0.6200.58
529_H563_Q0.6190.58
521_I561_Q0.6190.58
160_L171_R0.6180.57
47_Q159_H0.6180.57
438_R485_T0.6160.57
717_Y721_V0.6160.57
54_L87_A0.6160.57
167_P660_S0.6150.57
318_G346_D0.6140.57
69_L194_L0.6140.57
175_A206_L0.6140.57
553_L557_V0.6130.57
676_R708_A0.6130.57
390_S730_N0.6120.57
429_Y471_P0.6110.57
420_A454_Q0.6100.56
107_I156_R0.6070.56
262_K337_Q0.6070.56
472_S496_F0.6070.56
71_M191_I0.6070.56
78_A107_I0.6060.56
254_K278_A0.6060.56
265_K270_F0.6060.56
59_G111_R0.6060.56
133_D617_P0.6050.56
91_S714_I0.6050.56
160_L210_E0.6040.56
275_D337_Q0.6040.56
457_M721_V0.6040.56
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448_I464_I0.6030.56
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509_R540_D0.6030.56
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399_S407_Y0.6020.55
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238_A241_K0.6010.55
697_V708_A0.6010.55
680_L693_N0.6000.55
88_N91_S0.6000.55
131_Q150_V0.6000.55
328_G332_K0.6000.55
156_R177_E0.5990.55
183_A255_H0.5990.55
25_G103_V0.5990.55
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512_L556_M0.5980.55
20_W23_S0.5980.55
318_G345_E0.5970.55
254_K337_Q0.5960.55
262_K275_D0.5950.55
461_I586_T0.5950.55
674_N736_I0.5940.54
44_Q54_L0.5940.54
152_K156_R0.5940.54
18_E34_C0.5940.54
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600_E658_G0.5930.54
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337_Q354_H0.5920.54
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176_K206_L0.5760.52
252_R258_S0.5750.52
229_I450_P0.5750.52
143_V302_H0.5750.52
110_V114_A0.5740.52
425_L547_G0.5740.52
97_E587_P0.5730.52
233_V250_Y0.5730.52
115_A425_L0.5720.52
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200_D205_Y0.5720.52
669_V738_A0.5710.52
591_S633_V0.5710.52
301_R409_F0.5710.52
132_V401_V0.5700.51
215_A219_H0.5700.51
110_V294_G0.5700.51
373_R383_W0.5700.51
512_L542_L0.5690.51
55_L62_M0.5680.51
649_P652_I0.5680.51
39_W45_Q0.5670.51
671_V683_I0.5670.51
26_I31_S0.5660.51
265_K268_L0.5660.51
616_I740_R0.5660.51
273_L652_I0.5650.51
402_F497_R0.5640.51
561_Q564_F0.5630.51
402_F457_M0.5620.50
633_V692_V0.5620.50
198_L408_V0.5620.50
388_A485_T0.5620.50
279_V443_K0.5620.50
51_D62_M0.5610.50
433_S441_G0.5590.50
399_S405_R0.5590.50
104_V108_H0.5580.50
51_D86_D0.5560.50
111_R155_E0.5560.50
202_C421_G0.5550.50
533_R562_S0.5550.50
424_P451_F0.5550.50
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598_V609_I0.5530.49
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35_L38_T0.5520.49
52_A62_M0.5520.49
451_F502_D0.5520.49
294_G307_F0.5520.49
85_A94_V0.5510.49
546_I552_R0.5510.49
254_K352_A0.5510.49
320_Q342_Q0.5500.49
110_V152_K0.5500.49
369_G489_R0.5500.49
277_R332_K0.5500.49
536_F551_I0.5500.49
516_L560_L0.5500.49
681_R694_V0.5490.49
583_K586_T0.5480.49
53_S158_A0.5480.49
37_E498_K0.5480.49
15_F38_T0.5480.49
321_S339_R0.5480.49
412_K463_I0.5470.49
582_Q585_Y0.5460.48
275_D280_R0.5460.48
39_W94_V0.5460.48
496_F632_S0.5450.48
546_I688_A0.5450.48
158_A170_E0.5450.48
182_Y431_I0.5440.48
517_E599_V0.5440.48
82_F112_D0.5440.48
195_K259_I0.5440.48
52_A107_I0.5420.48
81_L95_L0.5400.48
623_G655_A0.5400.48
407_Y603_G0.5400.48
44_Q155_E0.5400.48
57_W79_A0.5390.48
278_A452_T0.5390.48
75_T106_L0.5390.48
683_I686_I0.5380.47
50_P167_P0.5380.47
278_A338_I0.5370.47
202_C205_Y0.5360.47
105_N279_V0.5350.47
51_D159_H0.5350.47
51_D88_N0.5340.47
463_I592_K0.5340.47
228_Y277_R0.5330.47
491_K494_A0.5330.47
544_A548_G0.5330.47
619_D635_R0.5320.47
675_D680_L0.5320.47
83_P155_E0.5320.47
456_Q459_D0.5310.47
290_Y324_T0.5310.47
438_R465_T0.5310.47
718_N731_Q0.5310.47
381_I401_V0.5310.47
124_T130_E0.5310.47
360_G363_A0.5310.47
344_H349_L0.5300.46
684_T710_I0.5300.46
439_C684_T0.5290.46
70_S139_L0.5290.46
727_G730_N0.5270.46
424_P448_I0.5270.46
703_T707_L0.5250.46
58_R99_V0.5250.46
483_V562_S0.5250.46
167_P174_A0.5240.46
292_A398_R0.5230.46
332_K610_A0.5230.46
255_H474_D0.5220.45
205_Y445_G0.5220.45
222_R256_I0.5220.45
195_K199_E0.5220.45
139_L487_R0.5220.45
273_L667_L0.5220.45
258_S335_E0.5210.45
407_Y630_G0.5210.45
19_K27_T0.5210.45
546_I556_M0.5210.45
138_M383_W0.5200.45
581_Q587_P0.5200.45
54_L58_R0.5200.45
156_R174_A0.5200.45
82_F88_N0.5190.45
298_T673_A0.5190.45
228_Y332_K0.5190.45
33_E45_Q0.5190.45
68_T696_G0.5180.45
51_D162_E0.5180.45
311_V630_G0.5180.45
70_S356_K0.5170.45
95_L174_A0.5160.45
377_L381_I0.5160.45
684_T734_D0.5160.45
504_N544_A0.5160.45
375_A379_K0.5160.45
407_Y601_G0.5150.45
431_I607_H0.5150.45
438_R692_V0.5140.44
49_H54_L0.5140.44
592_K633_V0.5130.44
254_K280_R0.5130.44
584_S588_Q0.5130.44
29_Q35_L0.5130.44
176_K207_H0.5130.44
397_V431_I0.5130.44
146_F317_N0.5120.44
81_L85_A0.5120.44
510_Q514_D0.5120.44
293_L312_A0.5120.44
461_I694_V0.5120.44
511_I546_I0.5120.44
74_D100_G0.5110.44
329_P334_V0.5110.44
721_V725_V0.5110.44
86_D152_K0.5110.44
42_C98_S0.5100.44
255_H344_H0.5090.44
567_P571_E0.5090.44
442_A491_K0.5090.44
204_R296_V0.5080.44
49_H152_K0.5080.44
132_V135_V0.5080.44
31_S38_T0.5080.44
313_N318_G0.5070.44
146_F305_D0.5060.44
353_A357_Y0.5060.44
152_K155_E0.5060.44
686_I714_I0.5060.44
85_A105_N0.5060.44
422_S736_I0.5060.44
392_E466_Q0.5050.43
79_A374_I0.5050.43
438_R467_K0.5050.43
67_S294_G0.5040.43
555_Q559_F0.5040.43
106_L113_M0.5030.43
40_A477_N0.5030.43
54_L83_P0.5030.43
301_R313_N0.5030.43
565_N669_V0.5030.43
191_I359_E0.5020.43
160_L170_E0.5020.43
411_P432_H0.5020.43
449_V729_L0.5020.43
280_R339_R0.5010.43
52_A155_E0.5010.43
596_R601_G0.5010.43
507_A510_Q0.5010.43
332_K439_C0.5010.43
296_V299_H0.5010.43
194_L588_Q0.5010.43
511_I553_L0.5010.43
151_I655_A0.5010.43
450_P453_Y0.5000.43
598_V658_G0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vj7A 1 0.4503 100 0.522 Contact Map
3l9dA 1 0.25 100 0.77 Contact Map
4yf1A 2 0.207 100 0.828 Contact Map
3nr1A 2 0.2339 100 0.836 Contact Map
2be3A 2 0.2581 100 0.836 Contact Map
3nqwA 2 0.2298 100 0.842 Contact Map
2ekiA 1 0.1129 99.9 0.924 Contact Map
3hvzA 2 0.086 99.7 0.937 Contact Map
1wxqA 1 0.2863 99.4 0.948 Contact Map
1wwtA 1 0.1169 99.4 0.948 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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