TRKH - ECOLI - GREMLIN Contacts

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TRKH - Trk system potassium uptake protein TrkH

UniProt:	P0AFZ7	Sequences: MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11021
Length:	483 (406)
Sequences:	5308 (3973)
Seq/√Len:	197.2

ECOLI - TRKH TRKG
BACSU - KTRB KTRD
HALSA - Q9HMF7 Q9HQ81 Q9HPA9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
411_S	461_N	4.232	1.00
345_G	351_G	4.227	1.00
100_D	455_K	3.520	1.00
243_A	309_F	3.343	1.00
197_A	211_I	3.343	1.00
99_T	456_W	3.187	1.00
200_L	242_I	3.152	1.00
196_C	245_F	2.966	1.00
414_A	457_I	2.905	1.00
136_W	193_T	2.901	1.00
325_S	328_R	2.640	1.00
203_A	235_S	2.588	1.00
346_C	356_V	2.527	1.00
135_Q	216_A	2.386	1.00
226_H	232_Y	2.384	1.00
199_A	241_I	2.368	1.00
102_F	459_I	2.347	1.00
228_A	232_Y	2.337	1.00
421_D	424_S	2.335	1.00
203_A	237_T	2.310	1.00
415_I	454_A	2.290	1.00
132_Q	212_G	2.273	1.00
300_S	303_M	2.230	1.00
315_M	337_L	2.160	1.00
201_W	207_A	2.144	1.00
125_H	129_F	2.131	1.00
99_T	459_I	2.097	1.00
412_M	426_F	2.096	1.00
128_L	208_F	2.079	1.00
203_A	241_I	2.049	1.00
239_N	307_Q	2.042	1.00
216_A	321_F	2.017	1.00
106_F	459_I	2.017	1.00
197_A	207_A	2.007	1.00
213_H	224_S	1.981	1.00
250_G	277_F	1.979	1.00
96_L	122_S	1.933	1.00
65_K	68_E	1.926	1.00
118_V	121_D	1.923	1.00
239_N	306_N	1.918	1.00
243_A	313_V	1.912	1.00
126_A	130_Y	1.906	1.00
203_A	238_I	1.852	1.00
99_T	452_P	1.835	1.00
247_L	281_Q	1.825	1.00
230_I	242_I	1.792	1.00
281_Q	316_A	1.781	1.00
285_V	309_F	1.779	1.00
201_W	210_A	1.774	1.00
97_T	100_D	1.757	1.00
338_L	430_V	1.749	1.00
237_T	241_I	1.748	1.00
247_L	313_V	1.746	1.00
64_L	68_E	1.735	1.00
199_A	237_T	1.720	1.00
81_G	98_I	1.717	1.00
239_N	323_T	1.694	1.00
411_S	457_I	1.689	1.00
218_I	249_S	1.687	1.00
428_S	443_V	1.684	1.00
302_L	306_N	1.679	1.00
240_T	244_I	1.661	1.00
362_L	401_F	1.658	1.00
408_F	430_V	1.653	1.00
115_T	119_G	1.652	1.00
236_P	306_N	1.649	1.00
414_A	453_V	1.648	1.00
293_W	297_V	1.638	1.00
288_C	312_V	1.631	1.00
85_A	98_I	1.629	1.00
284_L	340_S	1.607	1.00
431_A	436_L	1.604	1.00
361_L	389_L	1.598	1.00
240_T	306_N	1.593	1.00
291_V	336_L	1.591	1.00
276_M	360_L	1.574	1.00
289_T	308_A	1.542	1.00
367_N	371_K	1.526	1.00
183_K	187_L	1.515	1.00
354_L	359_I	1.514	1.00
119_G	122_S	1.514	1.00
226_H	233_F	1.506	1.00
408_F	433_L	1.496	1.00
246_L	319_A	1.494	1.00
197_A	214_S	1.487	1.00
418_T	451_N	1.481	1.00
289_T	305_I	1.480	1.00
85_A	89_I	1.473	1.00
424_S	440_L	1.472	1.00
64_L	72_I	1.465	1.00
107_S	223_F	1.465	1.00
246_L	314_S	1.453	1.00
96_L	123_L	1.444	1.00
217_T	242_I	1.435	1.00
439_G	443_V	1.430	1.00
200_L	238_I	1.428	1.00
278_I	282_F	1.421	1.00
456_W	460_A	1.420	1.00
285_V	313_V	1.408	1.00
98_I	102_F	1.407	1.00
104_E	116_T	1.402	1.00
420_V	442_V	1.399	1.00
244_I	248_I	1.396	1.00
412_M	429_V	1.394	1.00
312_V	315_M	1.393	1.00
99_T	455_K	1.393	1.00
212_G	225_T	1.387	1.00
318_T	436_L	1.382	1.00
199_A	203_A	1.381	1.00
240_T	302_L	1.381	1.00
128_L	132_Q	1.372	1.00
292_L	333_L	1.371	1.00
68_E	72_I	1.368	1.00
280_V	360_L	1.366	1.00
381_S	388_A	1.365	1.00
292_L	337_L	1.363	1.00
339_C	343_I	1.363	1.00
135_Q	221_G	1.362	1.00
81_G	106_F	1.361	1.00
456_W	459_I	1.360	1.00
205_M	238_I	1.359	1.00
89_I	126_A	1.359	1.00
343_I	356_V	1.344	1.00
404_Y	433_L	1.342	1.00
106_F	463_L	1.334	1.00
209_D	226_H	1.328	1.00
102_F	456_W	1.320	1.00
120_L	227_D	1.316	1.00
205_M	209_D	1.315	1.00
326_I	337_L	1.298	1.00
311_Q	323_T	1.297	1.00
297_V	304_T	1.295	1.00
234_D	303_M	1.294	1.00
338_L	426_F	1.284	1.00
207_A	211_I	1.280	1.00
105_S	134_L	1.280	1.00
334_P	440_L	1.271	1.00
217_T	321_F	1.267	1.00
108_G	223_F	1.266	1.00
240_T	309_F	1.265	1.00
408_F	412_M	1.262	1.00
274_F	278_I	1.260	1.00
283_T	287_I	1.257	1.00
301_A	305_I	1.252	1.00
96_L	117_L	1.246	1.00
280_V	356_V	1.246	1.00
196_C	214_S	1.241	1.00
420_V	425_A	1.231	1.00
231_G	322_T	1.228	1.00
411_S	429_V	1.223	1.00
201_W	206_D	1.223	1.00
240_T	305_I	1.222	1.00
179_A	183_K	1.221	1.00
125_H	208_F	1.220	1.00
192_L	248_I	1.219	1.00
64_L	67_R	1.217	1.00
293_W	304_T	1.214	1.00
442_V	449_S	1.214	1.00
119_G	227_D	1.202	1.00
287_I	291_V	1.200	1.00
213_H	225_T	1.198	1.00
307_Q	311_Q	1.197	1.00
81_G	102_F	1.192	1.00
88_F	134_L	1.189	1.00
342_F	408_F	1.187	1.00
100_D	116_T	1.185	1.00
236_P	239_N	1.183	1.00
450_M	458_L	1.180	1.00
460_A	464_F	1.179	1.00
231_G	325_S	1.178	1.00
429_V	461_N	1.176	1.00
102_F	106_F	1.169	1.00
343_I	359_I	1.166	1.00
239_N	243_A	1.166	1.00
303_M	307_Q	1.158	1.00
97_T	452_P	1.148	1.00
123_L	131_R	1.144	1.00
365_Q	398_W	1.139	1.00
247_L	278_I	1.139	1.00
118_V	227_D	1.136	1.00
326_I	329_W	1.131	1.00
132_Q	208_F	1.130	1.00
287_I	332_F	1.126	1.00
132_Q	211_I	1.125	1.00
293_W	301_A	1.123	1.00
251_C	274_F	1.120	1.00
258_S	271_D	1.119	1.00
307_Q	324_D	1.111	1.00
91_S	124_P	1.110	1.00
361_L	394_L	1.100	1.00
285_V	289_T	1.085	1.00
246_L	313_V	1.085	1.00
418_T	454_A	1.077	1.00
81_G	85_A	1.072	1.00
279_G	283_T	1.070	1.00
338_L	427_A	1.067	1.00
217_T	245_F	1.060	1.00
192_L	256_H	1.060	1.00
84_G	105_S	1.057	1.00
187_L	191_L	1.057	1.00
391_E	395_E	1.052	1.00
291_V	333_L	1.051	1.00
347_A	357_I	1.051	1.00
284_L	312_V	1.051	1.00
326_I	440_L	1.047	1.00
401_F	405_A	1.044	1.00
198_L	202_F	1.042	1.00
129_F	133_M	1.039	1.00
67_R	72_I	1.035	1.00
88_F	126_A	1.035	1.00
67_R	70_F	1.033	1.00
132_Q	215_F	1.030	1.00
451_N	454_A	1.026	1.00
450_M	454_A	1.022	1.00
412_M	425_A	1.017	1.00
236_P	240_T	1.016	1.00
279_G	385_G	1.015	1.00
200_L	217_T	1.015	1.00
196_C	241_I	1.011	1.00
117_L	123_L	1.009	1.00
228_A	231_G	1.007	1.00
206_D	210_A	1.005	1.00
330_P	333_L	1.005	1.00
432_T	458_L	1.005	1.00
193_T	214_S	0.997	1.00
307_Q	323_T	0.993	1.00
94_P	124_P	0.989	1.00
334_P	424_S	0.988	1.00
407_V	464_F	0.988	1.00
240_T	243_A	0.987	1.00
125_H	128_L	0.985	1.00
236_P	302_L	0.984	1.00
444_A	449_S	0.984	1.00
361_L	397_V	0.983	1.00
416_I	425_A	0.982	1.00
282_F	286_V	0.976	0.99
429_V	458_L	0.975	0.99
415_I	429_V	0.974	0.99
224_S	229_S	0.970	0.99
196_C	242_I	0.966	0.99
277_F	346_C	0.959	0.99
91_S	128_L	0.956	0.99
284_L	288_C	0.955	0.99
255_L	274_F	0.947	0.99
292_L	295_H	0.938	0.99
196_C	217_T	0.934	0.99
104_E	131_R	0.928	0.99
327_A	334_P	0.924	0.99
129_F	208_F	0.923	0.99
74_V	463_L	0.922	0.99
202_F	237_T	0.921	0.99
108_G	131_R	0.920	0.99
453_V	457_I	0.920	0.99
412_M	422_D	0.919	0.99
275_R	385_G	0.916	0.99
342_F	404_Y	0.916	0.99
272_P	385_G	0.914	0.99
200_L	241_I	0.912	0.99
140_M	186_W	0.911	0.99
284_L	336_L	0.909	0.99
68_E	71_L	0.909	0.99
89_I	98_I	0.908	0.99
332_F	413_L	0.908	0.99
196_C	200_L	0.907	0.99
119_G	123_L	0.906	0.99
369_E	395_E	0.901	0.99
90_F	96_L	0.899	0.99
247_L	285_V	0.898	0.99
418_T	453_V	0.896	0.99
243_A	289_T	0.896	0.99
454_A	458_L	0.895	0.99
90_F	95_N	0.894	0.99
213_H	226_H	0.892	0.99
65_K	72_I	0.891	0.99
289_T	293_W	0.888	0.99
286_V	289_T	0.888	0.99
363_F	367_N	0.875	0.99
121_D	227_D	0.875	0.99
224_S	227_D	0.875	0.99
268_Y	274_F	0.874	0.99
235_S	238_I	0.874	0.99
428_S	439_G	0.874	0.99
106_F	472_L	0.874	0.99
84_G	87_P	0.873	0.99
341_A	436_L	0.873	0.99
315_M	438_P	0.872	0.99
407_V	461_N	0.872	0.99
104_E	119_G	0.863	0.99
200_L	230_I	0.862	0.99
132_Q	135_Q	0.861	0.99
364_K	384_L	0.858	0.99
431_A	439_G	0.855	0.99
415_I	458_L	0.854	0.99
258_S	274_F	0.854	0.99
371_K	380_Y	0.846	0.99
225_T	233_F	0.843	0.98
188_I	192_L	0.841	0.98
230_I	238_I	0.841	0.98
89_I	124_P	0.840	0.98
256_H	268_Y	0.838	0.98
248_I	256_H	0.837	0.98
433_L	461_N	0.837	0.98
119_G	131_R	0.837	0.98
282_F	285_V	0.834	0.98
331_L	423_F	0.833	0.98
135_Q	219_A	0.832	0.98
327_A	440_L	0.831	0.98
194_V	198_L	0.827	0.98
311_Q	337_L	0.819	0.98
67_R	71_L	0.815	0.98
80_L	84_G	0.812	0.98
132_Q	216_A	0.810	0.98
347_A	356_V	0.805	0.98
312_V	340_S	0.803	0.98
365_Q	394_L	0.801	0.98
163_A	177_R	0.801	0.98
116_T	119_G	0.801	0.98
197_A	201_W	0.800	0.98
69_G	72_I	0.800	0.98
192_L	218_I	0.800	0.98
77_W	109_L	0.794	0.98
311_Q	326_I	0.792	0.98
114_A	431_A	0.790	0.98
206_D	209_D	0.790	0.98
262_G	265_L	0.789	0.98
289_T	309_F	0.788	0.98
403_A	470_F	0.788	0.98
76_F	109_L	0.788	0.98
177_R	180_E	0.787	0.98
276_M	356_V	0.787	0.98
86_L	90_F	0.786	0.98
271_D	385_G	0.782	0.98
338_L	423_F	0.782	0.98
366_G	399_G	0.779	0.97
336_L	413_L	0.778	0.97
180_E	183_K	0.776	0.97
449_S	452_P	0.774	0.97
430_V	434_N	0.772	0.97
209_D	213_H	0.770	0.97
184_T	257_F	0.769	0.97
285_V	308_A	0.765	0.97
364_K	382_I	0.765	0.97
416_I	422_D	0.764	0.97
109_L	134_L	0.760	0.97
221_G	318_T	0.758	0.97
71_L	75_L	0.755	0.97
341_A	431_A	0.755	0.97
212_G	216_A	0.753	0.97
329_W	333_L	0.753	0.97
198_L	201_W	0.746	0.97
362_L	402_S	0.745	0.97
293_W	308_A	0.738	0.96
98_I	456_W	0.736	0.96
191_L	195_A	0.735	0.96
291_V	295_H	0.734	0.96
82_S	102_F	0.733	0.96
206_D	233_F	0.732	0.96
427_A	438_P	0.731	0.96
362_L	366_G	0.729	0.96
145_L	186_W	0.728	0.96
124_P	127_I	0.726	0.96
104_E	115_T	0.724	0.96
301_A	304_T	0.723	0.96
266_K	269_W	0.722	0.96
71_L	463_L	0.720	0.96
302_L	305_I	0.717	0.96
368_R	382_I	0.711	0.96
213_H	242_I	0.711	0.96
91_S	127_I	0.710	0.96
250_G	345_G	0.707	0.96
335_V	422_D	0.707	0.96
324_D	329_W	0.705	0.95
366_G	403_A	0.704	0.95
469_V	473_L	0.704	0.95
243_A	247_L	0.699	0.95
77_W	106_F	0.698	0.95
135_Q	215_F	0.697	0.95
311_Q	314_S	0.692	0.95
188_I	256_H	0.691	0.95
99_T	458_L	0.690	0.95
114_A	432_T	0.690	0.95
115_T	131_R	0.685	0.95
251_C	256_H	0.685	0.95
423_F	440_L	0.684	0.95
204_G	208_F	0.684	0.95
189_Y	219_A	0.683	0.95
266_K	270_R	0.681	0.95
322_T	325_S	0.679	0.94
220_I	249_S	0.679	0.94
80_L	134_L	0.678	0.94
362_L	398_W	0.677	0.94
220_I	350_T	0.675	0.94
285_V	312_V	0.675	0.94
193_T	197_A	0.671	0.94
208_F	212_G	0.671	0.94
272_P	276_M	0.669	0.94
256_H	260_L	0.668	0.94
252_N	273_E	0.667	0.94
135_Q	321_F	0.666	0.94
255_L	271_D	0.666	0.94
425_A	442_V	0.666	0.94
364_K	367_N	0.664	0.94
136_W	189_Y	0.663	0.94
272_P	275_R	0.661	0.94
404_Y	434_N	0.660	0.94
379_V	383_K	0.660	0.94
443_V	450_M	0.660	0.94
103_F	116_T	0.658	0.93
412_M	416_I	0.658	0.93
254_G	348_G	0.656	0.93
305_I	309_F	0.655	0.93
243_A	285_V	0.654	0.93
213_H	321_F	0.650	0.93
272_P	360_L	0.650	0.93
368_R	391_E	0.649	0.93
403_A	407_V	0.648	0.93
203_A	233_F	0.647	0.93
158_M	179_A	0.647	0.93
297_V	301_A	0.646	0.93
281_Q	313_V	0.646	0.93
427_A	439_G	0.646	0.93
309_F	313_V	0.646	0.93
455_K	459_I	0.645	0.93
322_T	438_P	0.645	0.93
121_D	226_H	0.645	0.93
194_V	197_A	0.645	0.93
289_T	312_V	0.644	0.93
214_S	245_F	0.644	0.93
239_N	311_Q	0.643	0.93
315_M	340_S	0.643	0.93
331_L	334_P	0.643	0.93
115_T	120_L	0.642	0.93
196_C	199_A	0.642	0.93
230_I	233_F	0.641	0.93
230_I	239_N	0.641	0.93
86_L	126_A	0.640	0.92
181_T	349_S	0.640	0.92
207_A	210_A	0.640	0.92
82_S	98_I	0.639	0.92
234_D	239_N	0.639	0.92
417_A	451_N	0.637	0.92
78_T	81_G	0.637	0.92
422_D	425_A	0.636	0.92
231_G	323_T	0.636	0.92
439_G	444_A	0.634	0.92
120_L	128_L	0.634	0.92
265_L	269_W	0.632	0.92
90_F	122_S	0.632	0.92
86_L	89_I	0.632	0.92
191_L	194_V	0.631	0.92
101_A	105_S	0.629	0.92
407_V	433_L	0.628	0.92
237_T	240_T	0.627	0.92
339_C	409_I	0.626	0.92
163_A	179_A	0.625	0.92
186_W	190_V	0.625	0.92
288_C	308_A	0.624	0.92
220_I	319_A	0.624	0.92
283_T	286_V	0.623	0.91
406_L	410_V	0.619	0.91
234_D	307_Q	0.618	0.91
276_M	384_L	0.617	0.91
464_F	472_L	0.616	0.91
114_A	438_P	0.614	0.91
93_S	96_L	0.613	0.91
74_V	78_T	0.611	0.91
193_T	215_F	0.611	0.91
315_M	326_I	0.611	0.91
251_C	277_F	0.609	0.91
415_I	420_V	0.609	0.91
97_T	101_A	0.608	0.90
424_S	442_V	0.608	0.90
229_S	436_L	0.607	0.90
312_V	337_L	0.607	0.90
202_F	210_A	0.605	0.90
117_L	122_S	0.605	0.90
276_M	364_K	0.605	0.90
452_P	455_K	0.604	0.90
247_L	282_F	0.600	0.90
189_Y	193_T	0.600	0.90
415_I	450_M	0.599	0.90
427_A	431_A	0.599	0.90
273_E	277_F	0.599	0.90
114_A	439_G	0.595	0.90
431_A	443_V	0.595	0.90
366_G	402_S	0.595	0.90
163_A	166_P	0.593	0.89
209_D	225_T	0.592	0.89
310_F	321_F	0.591	0.89
425_A	429_V	0.590	0.89
420_V	450_M	0.587	0.89
288_C	291_V	0.587	0.89
288_C	333_L	0.587	0.89
96_L	100_D	0.587	0.89
280_V	343_I	0.586	0.89
117_L	120_L	0.585	0.89
404_Y	408_F	0.585	0.89
433_L	469_V	0.584	0.89
229_S	233_F	0.583	0.89
338_L	342_F	0.581	0.88
426_F	430_V	0.581	0.88
230_I	310_F	0.578	0.88
298_Y	307_Q	0.575	0.88
281_Q	285_V	0.575	0.88
415_I	432_T	0.575	0.88
192_L	249_S	0.573	0.88
452_P	456_W	0.573	0.88
294_F	297_V	0.571	0.88
314_S	438_P	0.569	0.87
428_S	431_A	0.569	0.87
150_L	475_L	0.569	0.87
428_S	438_P	0.566	0.87
408_F	426_F	0.566	0.87
129_F	204_G	0.564	0.87
65_K	71_L	0.563	0.87
408_F	429_V	0.562	0.87
286_V	301_A	0.561	0.87
85_A	95_N	0.560	0.87
111_T	220_I	0.560	0.87
193_T	218_I	0.560	0.87
327_A	442_V	0.557	0.86
289_T	292_L	0.557	0.86
420_V	424_S	0.555	0.86
414_A	418_T	0.555	0.86
114_A	443_V	0.554	0.86
428_S	458_L	0.554	0.86
415_I	418_T	0.553	0.86
129_F	132_Q	0.550	0.86
332_F	417_A	0.550	0.86
254_G	258_S	0.550	0.86
74_V	472_L	0.549	0.85
230_I	323_T	0.547	0.85
114_A	428_S	0.547	0.85
361_L	365_Q	0.547	0.85
391_E	394_L	0.546	0.85
345_G	356_V	0.545	0.85
350_T	355_K	0.545	0.85
175_R	181_T	0.543	0.85
338_L	440_L	0.542	0.85
70_F	474_V	0.541	0.85
115_T	216_A	0.541	0.85
213_H	230_I	0.540	0.84
449_S	453_V	0.540	0.84
311_Q	329_W	0.540	0.84
220_I	316_A	0.539	0.84
115_T	322_T	0.539	0.84
383_K	388_A	0.538	0.84
112_T	435_N	0.538	0.84
153_L	156_G	0.538	0.84
88_F	127_I	0.538	0.84
417_A	425_A	0.537	0.84
280_V	316_A	0.537	0.84
284_L	343_I	0.537	0.84
116_T	455_K	0.536	0.84
215_F	219_A	0.536	0.84
200_L	321_F	0.536	0.84
81_G	84_G	0.536	0.84
85_A	96_L	0.535	0.84
101_A	123_L	0.533	0.84
76_F	80_L	0.533	0.84
318_T	352_G	0.533	0.84
143_I	450_M	0.530	0.83
412_M	430_V	0.529	0.83
335_V	339_C	0.527	0.83
64_L	71_L	0.527	0.83
77_W	110_T	0.527	0.83
341_A	434_N	0.526	0.83
167_G	170_K	0.526	0.83
314_S	319_A	0.525	0.83
211_I	214_S	0.524	0.83
81_G	105_S	0.522	0.82
117_L	131_R	0.522	0.82
314_S	326_I	0.520	0.82
247_L	274_F	0.520	0.82
424_S	450_M	0.519	0.82
370_L	477_T	0.519	0.82
188_I	191_L	0.519	0.82
417_A	454_A	0.519	0.82
197_A	215_F	0.519	0.82
354_L	401_F	0.518	0.82
322_T	326_I	0.518	0.82
97_T	455_K	0.518	0.82
95_N	116_T	0.517	0.82
253_Y	349_S	0.516	0.82
239_N	310_F	0.514	0.82
107_S	112_T	0.514	0.82
89_I	101_A	0.512	0.81
246_L	312_V	0.512	0.81
94_P	127_I	0.512	0.81
185_L	466_R	0.512	0.81
310_F	323_T	0.512	0.81
129_F	212_G	0.511	0.81
122_S	125_H	0.509	0.81
291_V	332_F	0.508	0.81
304_T	308_A	0.507	0.81
242_I	321_F	0.507	0.81
116_T	120_L	0.507	0.81
318_T	435_N	0.506	0.81
82_S	85_A	0.506	0.81
178_I	182_A	0.505	0.80
181_T	186_W	0.505	0.80
353_G	359_I	0.505	0.80
305_I	308_A	0.504	0.80
275_R	279_G	0.503	0.80
390_P	393_I	0.502	0.80
233_F	238_I	0.502	0.80
77_W	84_G	0.502	0.80
370_L	473_L	0.501	0.80
229_S	323_T	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjzA	2	0.9648	100	0.071	Contact Map
4j7cI	2	0.8219	100	0.303	Contact Map
3ukmA	2	0.472	96.6	0.941	Contact Map
4twkA	2	0.4948	95.8	0.945	Contact Map
4bw5A	2	0.4907	95.4	0.947	Contact Map
4wfeA	2	0.4803	93.3	0.952	Contact Map
2a9hA	4	0.1967	91.6	0.954	Contact Map
2q67A	3	0.2153	91.1	0.955	Contact Map
3vouA	4	0.2754	90.4	0.956	Contact Map
2ih3C	4	0.1967	88.4	0.957	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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