GLRR - ECOLI - GREMLIN Contacts

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GLRR - Transcriptional regulatory protein GlrR

UniProt:	P0AFU4	Sequences: MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRVLNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFSFLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSVLINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDINVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFVEARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11285
Length:	444 (428)
Sequences:	9631 (6663)
Seq/√Len:	322.1

ECOLI - GLRR NTRC ATOC ZRAR NORR HYFR FHLA RTCR PRPR DHAR YGEV TYRR
BACSU - YQIR ACOR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
283_A	288_E	3.834	1.00
165_Q	308_A	3.766	1.00
209_A	219_N	3.753	1.00
33_V	50_V	3.218	1.00
410_T	420_M	3.216	1.00
194_G	246_V	3.069	1.00
223_L	258_R	2.942	1.00
282_K	286_R	2.877	1.00
150_A	173_F	2.673	1.00
225_Q	259_P	2.638	1.00
63_D	66_Q	2.607	1.00
38_G	62_M	2.594	1.00
256_K	265_D	2.588	1.00
257_V	268_I	2.533	1.00
18_L	36_E	2.501	1.00
37_S	40_E	2.443	1.00
416_H	419_R	2.423	1.00
256_K	267_D	2.420	1.00
324_Q	357_V	2.401	1.00
278_R	283_A	2.394	1.00
410_T	417_A	2.377	1.00
400_L	404_R	2.373	1.00
224_F	251_V	2.367	1.00
198_E	243_P	2.353	1.00
101_F	120_A	2.345	1.00
402_Y	406_L	2.248	1.00
315_P	341_M	2.245	1.00
18_L	34_T	2.208	1.00
279_D	282_K	2.167	1.00
233_F	275_A	2.163	1.00
336_F	360_I	2.154	1.00
36_E	40_E	2.107	1.00
11_V	41_G	2.088	1.00
69_A	98_Q	2.074	1.00
7_H	31_S	2.069	1.00
337_S	373_S	2.064	1.00
318_A	336_F	2.061	1.00
9_L	35_A	2.048	1.00
173_F	304_I	2.033	1.00
258_R	265_D	1.999	1.00
152_L	368_S	1.995	1.00
349_W	359_V	1.993	1.00
283_A	286_R	1.991	1.00
229_G	269_N	1.887	1.00
253_Q	357_V	1.887	1.00
209_A	262_S	1.887	1.00
239_D	278_R	1.862	1.00
347_A	350_P	1.862	1.00
282_K	285_A	1.812	1.00
315_P	345_M	1.803	1.00
409_I	420_M	1.787	1.00
252_L	272_I	1.782	1.00
39_A	61_E	1.778	1.00
130_E	133_R	1.764	1.00
209_A	259_P	1.756	1.00
311_T	315_P	1.752	1.00
224_F	232_L	1.718	1.00
311_T	314_I	1.671	1.00
139_R	316_L	1.663	1.00
183_R	269_N	1.663	1.00
52_L	117_I	1.655	1.00
22_G	34_T	1.652	1.00
168_T	304_I	1.642	1.00
42_L	70_E	1.634	1.00
163_N	303_K	1.628	1.00
46_N	74_V	1.619	1.00
151_R	180_A	1.617	1.00
319_N	341_M	1.610	1.00
45_L	71_I	1.598	1.00
340_A	344_L	1.572	1.00
274_S	297_L	1.570	1.00
320_H	324_Q	1.563	1.00
311_T	348_S	1.560	1.00
22_G	26_T	1.544	1.00
70_E	73_K	1.543	1.00
7_H	33_V	1.542	1.00
33_V	44_V	1.540	1.00
426_T	430_K	1.538	1.00
396_N	434_R	1.538	1.00
399_E	431_L	1.535	1.00
318_A	360_I	1.534	1.00
55_S	67_L	1.529	1.00
202_E	247_K	1.513	1.00
75_Q	78_M	1.505	1.00
337_S	340_A	1.493	1.00
262_S	266_I	1.492	1.00
53_V	71_I	1.468	1.00
335_A	371_V	1.466	1.00
221_E	225_Q	1.466	1.00
126_P	129_D	1.466	1.00
228_E	268_I	1.465	1.00
163_N	301_S	1.464	1.00
35_A	44_V	1.460	1.00
251_V	257_V	1.458	1.00
140_S	312_E	1.457	1.00
406_L	410_T	1.455	1.00
81_I	116_A	1.452	1.00
340_A	374_D	1.451	1.00
59_M	62_M	1.427	1.00
220_R	263_N	1.419	1.00
146_L	302_L	1.418	1.00
372_I	377_V	1.407	1.00
143_M	147_L	1.403	1.00
317_L	321_L	1.403	1.00
303_K	309_E	1.395	1.00
208_H	213_F	1.394	1.00
339_D	374_D	1.393	1.00
94_A	98_Q	1.393	1.00
228_E	269_N	1.391	1.00
171_E	250_R	1.383	1.00
328_R	361_E	1.369	1.00
148_E	151_R	1.367	1.00
153_V	300_V	1.363	1.00
55_S	82_I	1.363	1.00
28_E	114_Y	1.360	1.00
54_I	117_I	1.357	1.00
158_V	361_E	1.357	1.00
138_T	143_M	1.355	1.00
343_R	374_D	1.337	1.00
89_I	93_V	1.335	1.00
341_M	345_M	1.334	1.00
157_D	328_R	1.327	1.00
238_G	276_T	1.324	1.00
336_F	341_M	1.311	1.00
334_R	370_P	1.299	1.00
70_E	74_V	1.296	1.00
347_A	355_Q	1.294	1.00
325_A	364_V	1.288	1.00
147_L	150_A	1.287	1.00
38_G	67_L	1.287	1.00
44_V	50_V	1.286	1.00
280_L	289_F	1.280	1.00
406_L	420_M	1.277	1.00
186_K	229_G	1.272	1.00
405_K	409_I	1.265	1.00
91_D	103_F	1.259	1.00
37_S	61_E	1.256	1.00
68_F	80_V	1.251	1.00
8_L	30_Y	1.250	1.00
138_T	147_L	1.249	1.00
406_L	421_A	1.249	1.00
340_A	372_I	1.244	1.00
322_L	336_F	1.244	1.00
322_L	364_V	1.233	1.00
257_V	267_D	1.225	1.00
391_F	394_A	1.224	1.00
38_G	59_M	1.224	1.00
145_R	148_E	1.214	1.00
158_V	329_H	1.214	1.00
426_T	429_Y	1.211	1.00
24_R	110_K	1.207	1.00
373_S	376_L	1.203	1.00
30_Y	118_D	1.203	1.00
378_E	381_L	1.197	1.00
404_R	408_Q	1.196	1.00
53_V	78_M	1.194	1.00
149_Q	366_L	1.193	1.00
162_I	273_I	1.190	1.00
225_Q	266_I	1.189	1.00
427_E	431_L	1.188	1.00
201_L	244_L	1.184	1.00
424_N	427_E	1.182	1.00
414_V	429_Y	1.181	1.00
239_D	277_H	1.181	1.00
12_D	18_L	1.181	1.00
165_Q	306_A	1.181	1.00
204_E	220_R	1.180	1.00
136_I	147_L	1.177	1.00
259_P	262_S	1.176	1.00
402_Y	421_A	1.174	1.00
315_P	318_A	1.169	1.00
208_H	212_A	1.164	1.00
321_L	357_V	1.164	1.00
416_H	420_M	1.163	1.00
198_E	241_P	1.162	1.00
150_A	176_A	1.161	1.00
68_F	82_I	1.160	1.00
192_N	239_D	1.152	1.00
12_D	59_M	1.151	1.00
203_S	208_H	1.150	1.00
342_K	346_T	1.150	1.00
194_G	239_D	1.147	1.00
146_L	304_I	1.146	1.00
413_N	425_R	1.142	1.00
255_R	267_D	1.142	1.00
42_L	62_M	1.141	1.00
57_L	91_D	1.135	1.00
337_S	371_V	1.132	1.00
326_A	334_R	1.127	1.00
394_A	398_F	1.122	1.00
430_K	434_R	1.119	1.00
321_L	325_A	1.119	1.00
395_R	398_F	1.118	1.00
367_T	376_L	1.117	1.00
413_N	416_H	1.116	1.00
175_Q	190_A	1.113	1.00
415_T	419_R	1.108	1.00
33_V	48_E	1.106	1.00
157_D	183_R	1.105	1.00
238_G	280_L	1.102	1.00
58_R	86_H	1.101	1.00
137_V	320_H	1.099	1.00
225_Q	257_V	1.088	1.00
35_A	41_G	1.087	1.00
323_R	327_E	1.085	1.00
285_A	291_E	1.082	1.00
146_L	173_F	1.078	1.00
325_A	360_I	1.078	1.00
403_L	428_F	1.077	1.00
312_E	345_M	1.076	1.00
136_I	172_I	1.075	1.00
212_A	260_L	1.072	1.00
54_I	113_L	1.071	1.00
150_A	177_I	1.071	1.00
65_M	95_A	1.069	1.00
38_G	42_L	1.068	1.00
7_H	48_E	1.066	1.00
391_F	395_R	1.064	1.00
319_N	323_R	1.063	1.00
162_I	173_F	1.054	1.00
188_F	230_G	1.053	1.00
321_L	360_I	1.051	1.00
155_Q	182_P	1.048	1.00
55_S	59_M	1.047	1.00
55_S	80_V	1.047	1.00
161_L	274_S	1.040	1.00
326_A	332_F	1.038	1.00
281_P	285_A	1.033	1.00
417_A	420_M	1.032	1.00
52_L	121_L	1.030	1.00
7_H	50_V	1.023	1.00
171_E	190_A	1.019	1.00
213_F	216_A	1.017	1.00
66_Q	69_A	1.017	1.00
28_E	118_D	1.016	1.00
208_H	260_L	1.013	1.00
272_I	297_L	1.013	1.00
71_I	80_V	1.012	1.00
231_T	273_I	1.011	1.00
10_L	32_V	1.011	1.00
94_A	97_Q	1.011	1.00
424_N	430_K	1.010	1.00
406_L	417_A	1.009	1.00
150_A	302_L	1.006	1.00
415_T	425_R	1.005	1.00
390_T	393_E	1.001	1.00
201_L	205_L	0.995	1.00
136_I	173_F	0.990	1.00
228_E	270_V	0.986	1.00
407_L	432_L	0.984	1.00
159_S	255_R	0.971	1.00
339_D	373_S	0.967	1.00
281_P	380_A	0.966	1.00
138_T	173_F	0.966	1.00
135_A	179_N	0.964	1.00
311_T	345_M	0.963	1.00
362_Q	366_L	0.960	1.00
363_C	367_T	0.960	1.00
203_S	213_F	0.958	1.00
210_R	218_S	0.949	1.00
57_L	82_I	0.949	1.00
165_Q	168_T	0.947	1.00
158_V	299_V	0.945	1.00
67_L	71_I	0.941	1.00
401_N	405_K	0.939	1.00
226_A	263_N	0.937	1.00
314_I	344_L	0.936	1.00
69_A	94_A	0.931	1.00
398_F	402_Y	0.930	1.00
176_A	180_A	0.919	1.00
314_I	318_A	0.918	1.00
404_R	437_L	0.917	1.00
141_P	145_R	0.915	1.00
201_L	240_M	0.914	1.00
414_V	426_T	0.909	1.00
298_N	301_S	0.908	1.00
299_V	358_N	0.906	1.00
232_L	272_I	0.906	1.00
17_L	108_V	0.906	1.00
43_R	47_R	0.903	1.00
232_L	251_V	0.902	1.00
54_I	81_I	0.897	1.00
25_L	117_I	0.896	1.00
143_M	146_L	0.894	1.00
51_D	124_S	0.892	1.00
40_E	43_R	0.891	1.00
189_I	227_A	0.888	1.00
160_V	177_I	0.886	1.00
259_P	266_I	0.884	1.00
138_T	316_L	0.882	1.00
326_A	333_V	0.880	1.00
403_L	421_A	0.879	1.00
190_A	250_R	0.877	1.00
336_F	372_I	0.875	1.00
414_V	421_A	0.870	1.00
175_Q	179_N	0.868	1.00
12_D	17_L	0.865	1.00
37_S	59_M	0.865	1.00
157_D	182_P	0.864	1.00
342_K	345_M	0.863	1.00
319_N	335_A	0.863	1.00
162_I	304_I	0.861	1.00
403_L	431_L	0.858	1.00
407_L	414_V	0.854	1.00
192_N	240_M	0.852	1.00
405_K	408_Q	0.852	1.00
208_H	220_R	0.845	1.00
414_V	432_L	0.844	1.00
357_V	361_E	0.844	1.00
390_T	422_G	0.842	1.00
40_E	44_V	0.841	1.00
43_R	46_N	0.841	1.00
124_S	128_T	0.839	1.00
11_V	67_L	0.839	1.00
15_P	18_L	0.838	1.00
44_V	48_E	0.837	1.00
13_D	56_D	0.836	1.00
428_F	431_L	0.831	1.00
401_N	404_R	0.829	1.00
189_I	226_A	0.828	1.00
115_Q	126_P	0.823	1.00
115_Q	119_D	0.820	1.00
257_V	266_I	0.819	1.00
62_M	66_Q	0.817	1.00
224_F	270_V	0.817	1.00
44_V	47_R	0.816	1.00
421_A	431_L	0.816	1.00
427_E	430_K	0.816	1.00
122_E	125_A	0.815	1.00
407_L	417_A	0.815	1.00
119_D	126_P	0.815	1.00
423_R	427_E	0.811	1.00
240_M	244_L	0.810	1.00
97_Q	102_S	0.808	1.00
208_H	216_A	0.808	1.00
55_S	71_I	0.807	1.00
52_L	79_P	0.806	1.00
38_G	61_E	0.805	1.00
39_A	43_R	0.803	1.00
142_L	145_R	0.803	1.00
54_I	83_L	0.802	1.00
146_L	150_A	0.802	1.00
139_R	144_L	0.800	1.00
66_Q	70_E	0.799	1.00
10_L	21_L	0.797	1.00
338_T	341_M	0.797	1.00
281_P	294_Y	0.796	1.00
396_N	435_H	0.795	1.00
42_L	67_L	0.795	1.00
109_D	112_A	0.790	1.00
159_S	274_S	0.788	1.00
147_L	173_F	0.788	1.00
138_T	150_A	0.788	1.00
400_L	435_H	0.787	1.00
298_N	362_Q	0.786	1.00
93_V	97_Q	0.785	1.00
144_L	148_E	0.785	1.00
122_E	126_P	0.784	1.00
35_A	38_G	0.778	1.00
412_G	432_L	0.776	1.00
378_E	382_E	0.775	1.00
429_Y	433_S	0.775	1.00
363_C	372_I	0.773	1.00
284_M	294_Y	0.772	1.00
163_N	281_P	0.772	1.00
331_P	364_V	0.772	1.00
197_P	260_L	0.770	1.00
55_S	68_F	0.769	1.00
62_M	70_E	0.768	1.00
219_N	259_P	0.767	1.00
122_E	127_A	0.763	0.99
45_L	53_V	0.760	0.99
147_L	176_A	0.758	0.99
336_F	340_A	0.758	0.99
11_V	53_V	0.757	0.99
21_L	113_L	0.757	0.99
318_A	341_M	0.756	0.99
425_R	429_Y	0.756	0.99
158_V	300_V	0.754	0.99
250_R	254_E	0.752	0.99
69_A	73_K	0.752	0.99
424_N	429_Y	0.750	0.99
8_L	25_L	0.750	0.99
224_F	268_I	0.747	0.99
226_A	262_S	0.747	0.99
35_A	40_E	0.745	0.99
281_P	291_E	0.742	0.99
240_M	248_L	0.739	0.99
219_N	264_R	0.737	0.99
153_V	160_V	0.736	0.99
221_E	226_A	0.736	0.99
72_Q	79_P	0.735	0.99
136_I	143_M	0.733	0.99
395_R	402_Y	0.732	0.99
421_A	427_E	0.729	0.99
68_F	100_V	0.729	0.99
394_A	397_Q	0.728	0.99
89_I	92_A	0.725	0.99
359_V	363_C	0.725	0.99
9_L	50_V	0.724	0.99
135_A	176_A	0.723	0.99
429_Y	432_L	0.723	0.99
154_A	181_S	0.719	0.99
238_G	277_H	0.716	0.99
45_L	75_Q	0.715	0.99
314_I	345_M	0.715	0.99
315_P	319_N	0.714	0.99
30_Y	114_Y	0.711	0.99
428_F	432_L	0.711	0.99
83_L	108_V	0.706	0.99
158_V	365_A	0.706	0.99
92_A	100_V	0.705	0.99
118_D	122_E	0.705	0.99
39_A	62_M	0.705	0.99
13_D	85_A	0.704	0.99
403_L	432_L	0.702	0.99
87_G	105_T	0.700	0.99
223_L	226_A	0.700	0.99
10_L	22_G	0.700	0.99
13_D	106_K	0.699	0.99
137_V	316_L	0.699	0.99
331_P	334_R	0.698	0.99
56_D	106_K	0.696	0.99
306_A	309_E	0.695	0.99
13_D	84_T	0.693	0.99
24_R	114_Y	0.693	0.99
425_R	430_K	0.692	0.99
191_I	232_L	0.691	0.99
393_E	397_Q	0.689	0.99
294_Y	298_N	0.689	0.99
318_A	363_C	0.684	0.99
237_I	297_L	0.680	0.99
152_L	376_L	0.680	0.99
144_L	147_L	0.679	0.99
212_A	216_A	0.679	0.99
21_L	83_L	0.679	0.99
214_T	275_A	0.677	0.99
221_E	263_N	0.677	0.99
219_N	262_S	0.677	0.99
103_F	112_A	0.676	0.99
90_P	94_A	0.675	0.99
45_L	78_M	0.675	0.99
87_G	92_A	0.674	0.99
325_A	357_V	0.674	0.99
432_L	437_L	0.672	0.99
14_D	17_L	0.671	0.99
423_R	428_F	0.666	0.99
141_P	144_L	0.665	0.99
79_P	127_A	0.662	0.99
7_H	51_D	0.662	0.99
410_T	416_H	0.660	0.99
334_R	364_V	0.659	0.99
64_G	106_K	0.658	0.99
152_L	331_P	0.657	0.98
65_M	94_A	0.657	0.98
431_L	435_H	0.656	0.98
197_P	200_L	0.656	0.98
325_A	329_H	0.656	0.98
392_V	406_L	0.656	0.98
196_L	205_L	0.654	0.98
311_T	316_L	0.653	0.98
363_C	377_V	0.651	0.98
162_I	174_A	0.649	0.98
224_F	257_V	0.647	0.98
343_R	377_V	0.647	0.98
281_P	301_S	0.646	0.98
208_H	217_V	0.646	0.98
15_P	19_K	0.646	0.98
220_R	223_L	0.645	0.98
343_R	347_A	0.645	0.98
11_V	59_M	0.645	0.98
338_T	342_K	0.643	0.98
116_A	120_A	0.643	0.98
211_G	216_A	0.641	0.98
45_L	50_V	0.639	0.98
133_R	176_A	0.638	0.98
152_L	366_L	0.637	0.98
102_S	116_A	0.637	0.98
13_D	64_G	0.637	0.98
108_V	113_L	0.637	0.98
430_K	433_S	0.635	0.98
57_L	63_D	0.634	0.98
53_V	67_L	0.631	0.98
209_A	266_I	0.629	0.98
394_A	402_Y	0.623	0.98
139_R	312_E	0.622	0.98
133_R	147_L	0.619	0.98
413_N	429_Y	0.619	0.98
208_H	219_N	0.615	0.98
200_L	214_T	0.615	0.98
23_L	27_S	0.614	0.98
210_R	216_A	0.614	0.98
104_L	108_V	0.613	0.98
238_G	289_F	0.613	0.98
414_V	431_L	0.610	0.98
393_E	401_N	0.610	0.98
214_T	277_H	0.609	0.98
281_P	284_M	0.609	0.98
408_Q	412_G	0.607	0.97
238_G	275_A	0.605	0.97
209_A	225_Q	0.605	0.97
391_F	421_A	0.603	0.97
238_G	278_R	0.602	0.97
79_P	123_Q	0.601	0.97
148_E	368_S	0.601	0.97
255_R	270_V	0.601	0.97
414_V	425_R	0.600	0.97
426_T	433_S	0.599	0.97
172_I	176_A	0.599	0.97
146_L	149_Q	0.599	0.97
141_P	312_E	0.596	0.97
142_L	309_E	0.594	0.97
414_V	417_A	0.594	0.97
322_L	360_I	0.592	0.97
20_L	24_R	0.591	0.97
149_Q	152_L	0.589	0.97
166_S	239_D	0.589	0.97
399_E	403_L	0.587	0.97
9_L	41_G	0.587	0.97
392_V	431_L	0.585	0.97
224_F	272_I	0.584	0.97
123_Q	126_P	0.584	0.97
391_F	398_F	0.583	0.97
318_A	322_L	0.583	0.97
154_A	180_A	0.582	0.97
396_N	400_L	0.582	0.97
407_L	412_G	0.581	0.97
220_R	226_A	0.579	0.97
326_A	364_V	0.578	0.97
46_N	70_E	0.576	0.97
329_H	364_V	0.576	0.97
101_F	116_A	0.575	0.97
228_E	267_D	0.574	0.96
146_L	153_V	0.574	0.96
406_L	424_N	0.573	0.96
229_G	270_V	0.571	0.96
53_V	80_V	0.571	0.96
84_T	106_K	0.570	0.96
41_G	67_L	0.569	0.96
423_R	431_L	0.569	0.96
155_Q	181_S	0.569	0.96
395_R	431_L	0.568	0.96
325_A	328_R	0.568	0.96
397_Q	401_N	0.567	0.96
233_F	273_I	0.566	0.96
223_L	265_D	0.565	0.96
343_R	381_L	0.564	0.96
300_V	365_A	0.560	0.96
26_T	32_V	0.560	0.96
398_F	421_A	0.560	0.96
325_A	361_E	0.560	0.96
403_L	435_H	0.558	0.96
87_G	103_F	0.557	0.96
83_L	86_H	0.556	0.96
425_R	428_F	0.556	0.96
50_V	78_M	0.555	0.96
79_P	124_S	0.555	0.96
90_P	112_A	0.554	0.96
108_V	429_Y	0.552	0.96
18_L	38_G	0.552	0.96
228_E	255_R	0.551	0.96
326_A	331_P	0.550	0.96
22_G	32_V	0.548	0.95
112_A	115_Q	0.547	0.95
150_A	180_A	0.544	0.95
71_I	78_M	0.544	0.95
171_E	254_E	0.544	0.95
210_R	217_V	0.544	0.95
221_E	257_V	0.543	0.95
37_S	60_D	0.542	0.95
414_V	430_K	0.539	0.95
37_S	62_M	0.538	0.95
415_T	418_A	0.537	0.95
204_E	223_L	0.537	0.95
173_F	176_A	0.536	0.95
105_T	112_A	0.535	0.95
112_A	116_A	0.535	0.95
251_V	254_E	0.535	0.95
226_A	257_V	0.534	0.95
413_N	417_A	0.534	0.95
16_G	20_L	0.533	0.95
413_N	430_K	0.533	0.95
402_Y	417_A	0.533	0.95
359_V	381_L	0.533	0.95
156_S	365_A	0.532	0.95
293_L	297_L	0.532	0.95
397_Q	400_L	0.532	0.95
200_L	260_L	0.532	0.95
138_T	176_A	0.531	0.95
203_S	211_G	0.530	0.95
333_V	364_V	0.530	0.95
191_I	223_L	0.529	0.94
121_L	124_S	0.529	0.94
83_L	104_L	0.528	0.94
209_A	212_A	0.527	0.94
192_N	195_A	0.527	0.94
316_L	319_N	0.527	0.94
110_K	114_Y	0.526	0.94
157_D	329_H	0.523	0.94
402_Y	429_Y	0.523	0.94
192_N	246_V	0.522	0.94
149_Q	300_V	0.522	0.94
58_R	88_S	0.522	0.94
148_E	152_L	0.521	0.94
101_F	123_Q	0.521	0.94
136_I	176_A	0.520	0.94
223_L	263_N	0.520	0.94
235_D	354_R	0.519	0.94
251_V	268_I	0.518	0.94
10_L	25_L	0.518	0.94
8_L	121_L	0.517	0.94
278_R	288_E	0.517	0.94
25_L	32_V	0.516	0.94
191_I	205_L	0.515	0.94
183_R	186_K	0.515	0.94
64_G	85_A	0.515	0.94
219_N	266_I	0.514	0.94
322_L	333_V	0.514	0.94
312_E	315_P	0.514	0.94
402_Y	414_V	0.514	0.94
238_G	283_A	0.513	0.94
145_R	149_Q	0.513	0.94
205_L	244_L	0.512	0.94
8_L	52_L	0.512	0.94
213_F	220_R	0.511	0.93
142_L	312_E	0.510	0.93
421_A	428_F	0.510	0.93
426_T	431_L	0.509	0.93
13_D	59_M	0.509	0.93
200_L	213_F	0.509	0.93
186_K	228_E	0.508	0.93
59_M	64_G	0.508	0.93
392_V	395_R	0.508	0.93
209_A	260_L	0.507	0.93
174_A	188_F	0.507	0.93
168_T	172_I	0.506	0.93
322_L	326_A	0.505	0.93
187_P	226_A	0.503	0.93
59_M	63_D	0.502	0.93
212_A	219_N	0.502	0.93
57_L	108_V	0.502	0.93
176_A	179_N	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.8491	100	0.124	Contact Map
3dzdA	2	0.8288	100	0.285	Contact Map
1ojlA	3	0.6757	100	0.467	Contact Map
4fwgA	3	0.7815	100	0.632	Contact Map
1r6bX	1	0.8626	100	0.659	Contact Map
3pxiA	3	0.8086	100	0.663	Contact Map
1qvrA	3	0.8378	100	0.666	Contact Map
4d2uA	3	0.8559	100	0.674	Contact Map
4qhsA	3	0.5495	100	0.674	Contact Map
4ciuA	1	0.8401	100	0.674	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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