YFBS - ECOLI - GREMLIN Contacts

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YFBS - Uncharacterized transporter YfbS

UniProt:	P0AFU2	Sequences: MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLTVPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTVAGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLVVNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFRDLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVNGVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPESELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGMLAKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLMGKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMMLGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPVSSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14103
Length:	610 (584)
Sequences:	1764 (1329)
Seq/√Len:	55.0

ECOLI - YFBS
HALSA - Q9HMC9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
138_M	142_F	5.942	1.00
69_G	450_M	5.844	1.00
235_I	281_F	5.095	1.00
428_M	446_A	4.800	1.00
47_E	485_K	4.674	1.00
146_I	189_G	4.484	1.00
490_A	494_K	4.249	1.00
553_V	604_I	3.918	1.00
431_L	436_E	3.792	1.00
329_I	382_V	3.771	1.00
9_L	488_G	3.487	1.00
50_S	481_V	3.456	1.00
103_A	186_L	3.432	1.00
600_C	604_I	3.327	1.00
424_C	449_L	3.300	1.00
242_I	283_A	3.234	1.00
188_L	599_V	3.212	1.00
7_W	42_T	3.173	1.00
44_T	47_E	3.168	1.00
504_G	507_M	3.096	1.00
545_V	550_F	3.068	1.00
233_L	289_I	3.061	1.00
180_P	184_V	3.035	1.00
603_M	607_L	2.965	1.00
184_V	603_M	2.954	1.00
6_I	10_S	2.939	1.00
517_A	593_T	2.915	1.00
516_S	532_M	2.908	1.00
183_L	187_V	2.822	1.00
342_V	355_V	2.697	1.00
503_Y	507_M	2.696	1.00
400_V	404_L	2.544	1.00
27_D	462_Y	2.522	1.00
11_L	36_A	2.521	1.00
500_G	511_C	2.520	1.00
546_S	549_P	2.515	1.00
264_R	285_D	2.515	1.00
586_V	590_V	2.515	1.00
15_A	33_V	2.487	1.00
90_S	93_K	2.460	1.00
429_V	433_L	2.431	1.00
483_L	488_G	2.425	1.00
244_Q	248_D	2.421	1.00
9_L	13_A	2.416	1.00
398_D	402_L	2.378	1.00
66_I	446_A	2.366	1.00
424_C	446_A	2.362	1.00
246_L	259_V	2.322	1.00
66_I	428_M	2.317	1.00
423_F	427_L	2.308	1.00
49_F	440_P	2.289	1.00
187_V	191_L	2.265	1.00
422_I	426_V	2.238	1.00
116_A	573_L	2.216	1.00
52_F	58_V	2.203	1.00
174_S	177_S	2.157	1.00
583_S	586_V	2.149	1.00
192_Y	588_L	2.148	1.00
353_L	384_G	2.147	1.00
427_L	449_L	2.141	1.00
447_C	451_G	2.141	1.00
65_I	465_I	2.135	1.00
400_V	403_N	2.126	1.00
331_L	374_L	2.111	1.00
102_V	144_G	2.055	1.00
99_M	143_A	2.040	1.00
179_T	183_L	2.034	1.00
44_T	485_K	2.029	1.00
162_N	166_L	2.018	1.00
177_S	548_Y	2.003	1.00
196_M	199_M	1.992	1.00
437_I	445_I	1.991	1.00
338_I	376_L	1.979	1.00
61_A	470_I	1.973	1.00
237_P	283_A	1.959	1.00
262_V	279_S	1.951	1.00
72_R	460_S	1.928	1.00
38_A	48_V	1.926	1.00
563_M	590_V	1.919	1.00
43_L	485_K	1.908	1.00
327_A	382_V	1.896	1.00
192_Y	595_I	1.877	0.99
506_H	605_P	1.867	0.99
150_M	179_T	1.865	0.99
17_V	21_T	1.860	0.99
91_E	135_R	1.857	0.99
15_A	479_F	1.855	0.99
99_M	190_I	1.855	0.99
106_G	147_S	1.820	0.99
495_G	499_I	1.812	0.99
150_M	186_L	1.782	0.99
98_L	122_V	1.764	0.99
5_L	488_G	1.750	0.99
10_S	14_V	1.742	0.99
514_V	597_M	1.739	0.99
509_L	550_F	1.738	0.99
165_L	551_A	1.728	0.99
193_M	588_L	1.721	0.99
150_M	183_L	1.706	0.99
14_V	36_A	1.694	0.99
540_A	550_F	1.680	0.99
59_L	110_S	1.671	0.99
18_L	21_T	1.662	0.99
185_V	596_V	1.660	0.99
43_L	478_P	1.651	0.99
398_D	404_L	1.646	0.99
38_A	441_V	1.640	0.99
165_L	170_Y	1.639	0.99
192_Y	592_F	1.632	0.99
510_G	601_V	1.629	0.99
189_G	592_F	1.625	0.98
42_T	486_T	1.622	0.98
144_G	149_M	1.620	0.98
11_L	33_V	1.616	0.98
161_V	529_A	1.599	0.98
179_T	184_V	1.597	0.98
119_I	573_L	1.589	0.98
521_L	593_T	1.584	0.98
424_C	450_M	1.579	0.98
457_D	461_A	1.571	0.98
597_M	601_V	1.554	0.98
430_A	434_T	1.552	0.98
108_F	176_F	1.552	0.98
111_S	144_G	1.547	0.98
553_V	557_A	1.527	0.98
538_A	541_K	1.504	0.97
513_F	597_M	1.495	0.97
63_L	428_M	1.491	0.97
161_V	533_A	1.484	0.97
35_V	448_L	1.472	0.97
484_Q	490_A	1.456	0.97
14_V	18_L	1.447	0.97
63_L	66_I	1.440	0.97
245_R	248_D	1.430	0.97
427_L	431_L	1.429	0.97
583_S	587_K	1.425	0.97
397_R	402_L	1.413	0.96
192_Y	196_M	1.405	0.96
43_L	486_T	1.390	0.96
51_G	474_V	1.390	0.96
5_L	491_L	1.389	0.96
177_S	546_S	1.383	0.96
521_L	561_A	1.381	0.96
358_L	372_E	1.377	0.96
594_I	598_A	1.375	0.96
102_V	118_F	1.374	0.96
291_M	298_L	1.369	0.96
563_M	593_T	1.366	0.96
505_P	509_L	1.364	0.96
178_V	552_M	1.360	0.95
7_W	40_S	1.352	0.95
66_I	425_L	1.352	0.95
516_S	557_A	1.346	0.95
435_D	438_P	1.345	0.95
146_I	596_V	1.340	0.95
181_I	556_M	1.336	0.95
564_T	582_F	1.334	0.95
331_L	342_V	1.331	0.95
197_R	588_L	1.330	0.95
62_A	443_A	1.327	0.95
69_G	421_A	1.317	0.95
141_S	570_V	1.311	0.94
397_R	401_A	1.309	0.94
326_M	356_V	1.308	0.94
147_S	154_A	1.294	0.94
525_N	559_S	1.292	0.94
431_L	437_I	1.289	0.94
56_N	59_L	1.282	0.94
549_P	605_P	1.278	0.94
397_R	404_L	1.277	0.94
358_L	365_L	1.275	0.94
111_S	145_L	1.273	0.94
69_G	446_A	1.261	0.93
178_V	555_A	1.254	0.93
439_N	443_A	1.252	0.93
157_P	568_S	1.251	0.93
115_V	570_V	1.250	0.93
236_R	308_E	1.241	0.93
602_V	605_P	1.236	0.92
18_L	32_F	1.231	0.92
11_L	40_S	1.228	0.92
52_F	474_V	1.227	0.92
259_V	289_I	1.214	0.92
69_G	455_C	1.213	0.92
57_V	113_G	1.213	0.92
401_A	404_L	1.213	0.92
104_G	108_F	1.210	0.92
184_V	187_V	1.202	0.91
19_F	30_A	1.201	0.91
605_P	608_F	1.196	0.91
98_L	102_V	1.189	0.91
397_R	400_V	1.188	0.91
19_F	476_M	1.188	0.91
34_I	52_F	1.187	0.91
510_G	597_M	1.179	0.91
181_I	603_M	1.168	0.90
447_C	450_M	1.167	0.90
325_G	386_W	1.164	0.90
65_I	447_C	1.163	0.90
234_A	308_E	1.161	0.90
566_V	582_F	1.161	0.90
99_M	193_M	1.158	0.90
51_G	478_P	1.155	0.90
233_L	302_C	1.150	0.89
173_F	572_T	1.150	0.89
508_M	512_L	1.148	0.89
68_D	464_S	1.148	0.89
238_G	242_I	1.147	0.89
57_V	474_V	1.143	0.89
341_S	373_P	1.142	0.89
30_A	472_L	1.141	0.89
398_D	401_A	1.115	0.88
235_I	284_R	1.115	0.88
518_V	595_I	1.115	0.88
521_L	567_S	1.112	0.88
60_I	526_T	1.103	0.87
54_D	163_S	1.101	0.87
508_M	543_M	1.101	0.87
13_A	17_V	1.099	0.87
156_P	568_S	1.098	0.87
145_L	524_S	1.096	0.87
480_A	530_V	1.094	0.87
517_A	563_M	1.090	0.87
239_S	242_I	1.085	0.87
462_Y	467_W	1.085	0.87
112_T	568_S	1.085	0.87
16_I	522_F	1.082	0.86
552_M	605_P	1.080	0.86
341_S	355_V	1.077	0.86
513_F	593_T	1.073	0.86
191_L	522_F	1.071	0.86
141_S	574_V	1.071	0.86
514_V	594_I	1.066	0.86
82_W	85_K	1.063	0.85
536_A	554_V	1.060	0.85
245_R	287_L	1.059	0.85
233_L	283_A	1.058	0.85
497_M	539_A	1.056	0.85
432_M	439_N	1.055	0.85
499_I	507_M	1.052	0.85
113_G	478_P	1.051	0.85
417_Q	455_C	1.051	0.85
537_L	541_K	1.050	0.85
237_P	284_R	1.046	0.84
73_T	80_G	1.045	0.84
40_S	43_L	1.045	0.84
196_M	588_L	1.034	0.84
12_L	488_G	1.033	0.84
329_I	399_F	1.032	0.84
238_G	283_A	1.029	0.83
164_E	533_A	1.028	0.83
135_R	203_D	1.027	0.83
329_I	379_I	1.020	0.83
113_G	156_P	1.020	0.83
418_A	421_A	1.007	0.82
130_Q	352_G	1.006	0.82
428_M	443_A	1.004	0.82
15_A	29_V	1.001	0.82
499_I	502_G	1.000	0.82
483_L	489_V	0.994	0.81
107_A	150_M	0.993	0.81
460_S	486_T	0.992	0.81
65_I	453_F	0.991	0.81
543_M	550_F	0.991	0.81
193_M	198_F	0.989	0.81
235_I	283_A	0.987	0.81
135_R	138_M	0.982	0.80
66_I	473_I	0.978	0.80
567_S	570_V	0.977	0.80
148_G	154_A	0.977	0.80
467_W	478_P	0.975	0.80
437_I	535_I	0.975	0.80
526_T	568_S	0.975	0.80
431_L	434_T	0.974	0.80
32_F	36_A	0.970	0.80
27_D	74_G	0.968	0.80
513_F	557_A	0.966	0.79
556_M	604_I	0.965	0.79
236_R	283_A	0.963	0.79
156_P	439_N	0.961	0.79
111_S	558_A	0.959	0.79
115_V	568_S	0.955	0.79
354_N	383_V	0.953	0.78
347_F	353_L	0.952	0.78
63_L	443_A	0.951	0.78
513_F	521_L	0.950	0.78
177_S	180_P	0.946	0.78
384_G	418_A	0.942	0.78
234_A	286_V	0.940	0.77
70_L	529_A	0.938	0.77
494_K	498_D	0.934	0.77
49_F	58_V	0.934	0.77
111_S	148_G	0.933	0.77
341_S	344_E	0.930	0.77
37_F	479_F	0.929	0.77
602_V	606_M	0.925	0.76
162_N	172_G	0.923	0.76
37_F	143_A	0.923	0.76
450_M	454_R	0.921	0.76
355_V	380_I	0.920	0.76
188_L	592_F	0.918	0.76
521_L	570_V	0.912	0.75
92_I	198_F	0.909	0.75
438_P	442_A	0.908	0.75
489_V	493_V	0.908	0.75
512_L	536_A	0.907	0.75
554_V	581_S	0.906	0.75
461_A	464_S	0.905	0.75
149_M	561_A	0.903	0.75
68_D	425_L	0.899	0.74
96_V	100_L	0.898	0.74
17_V	23_R	0.898	0.74
327_A	384_G	0.897	0.74
110_S	158_N	0.897	0.74
188_L	595_I	0.896	0.74
138_M	588_L	0.894	0.74
191_L	195_V	0.893	0.74
342_V	358_L	0.892	0.74
156_P	575_L	0.892	0.74
426_V	430_A	0.890	0.74
156_P	570_V	0.890	0.74
92_I	95_L	0.889	0.73
163_S	477_M	0.889	0.73
177_S	604_I	0.887	0.73
110_S	568_S	0.887	0.73
177_S	543_M	0.885	0.73
508_M	550_F	0.883	0.73
75_V	102_V	0.881	0.73
79_M	235_I	0.880	0.73
110_S	526_T	0.880	0.73
533_A	551_A	0.880	0.73
431_L	435_D	0.879	0.73
156_P	526_T	0.879	0.73
157_P	570_V	0.879	0.73
473_I	569_P	0.877	0.72
507_M	598_A	0.876	0.72
492_A	535_I	0.870	0.72
8_V	42_T	0.867	0.72
538_A	542_T	0.865	0.71
348_R	354_N	0.860	0.71
34_I	478_P	0.859	0.71
133_P	140_L	0.858	0.71
239_S	243_G	0.856	0.71
181_I	608_F	0.854	0.70
399_F	403_N	0.852	0.70
396_G	402_L	0.852	0.70
346_G	349_T	0.851	0.70
522_F	555_A	0.851	0.70
264_R	282_R	0.848	0.70
241_M	249_L	0.846	0.70
42_T	482_A	0.845	0.70
153_V	175_F	0.842	0.69
141_S	568_S	0.842	0.69
59_L	569_P	0.841	0.69
157_P	521_L	0.839	0.69
443_A	568_S	0.839	0.69
48_V	425_L	0.839	0.69
368_S	371_D	0.839	0.69
348_R	351_Y	0.839	0.69
15_A	19_F	0.838	0.69
114_V	119_I	0.837	0.69
237_P	452_K	0.836	0.69
112_T	157_P	0.835	0.69
449_L	515_L	0.835	0.69
42_T	485_K	0.834	0.69
603_M	606_M	0.833	0.68
114_V	568_S	0.833	0.68
177_S	608_F	0.832	0.68
106_G	154_A	0.831	0.68
497_M	504_G	0.829	0.68
197_R	202_G	0.829	0.68
343_R	371_D	0.827	0.68
26_M	524_S	0.825	0.68
145_L	562_F	0.823	0.68
431_L	445_I	0.823	0.68
515_L	535_I	0.822	0.67
15_A	417_Q	0.820	0.67
448_L	554_V	0.818	0.67
113_G	157_P	0.818	0.67
491_L	495_G	0.816	0.67
84_V	125_V	0.816	0.67
24_V	29_V	0.815	0.67
360_R	378_D	0.814	0.67
8_V	11_L	0.813	0.67
28_A	465_I	0.813	0.67
37_F	482_A	0.811	0.66
329_I	401_A	0.811	0.66
181_I	607_L	0.809	0.66
56_N	160_V	0.809	0.66
590_V	594_I	0.809	0.66
146_I	576_G	0.808	0.66
505_P	545_V	0.807	0.66
197_R	201_K	0.806	0.66
184_V	607_L	0.806	0.66
231_R	369_L	0.804	0.66
59_L	443_A	0.801	0.65
113_G	568_S	0.799	0.65
398_D	403_N	0.798	0.65
402_L	408_V	0.798	0.65
97_L	388_L	0.796	0.65
488_G	491_L	0.796	0.65
57_V	575_L	0.795	0.65
205_Q	430_A	0.795	0.65
513_F	560_A	0.794	0.65
31_L	52_F	0.794	0.65
477_M	530_V	0.793	0.65
523_I	561_A	0.793	0.65
192_Y	591_P	0.793	0.65
420_H	519_I	0.792	0.65
144_G	539_A	0.791	0.64
22_G	575_L	0.790	0.64
111_S	520_G	0.790	0.64
362_G	399_F	0.786	0.64
431_L	442_A	0.785	0.64
8_V	37_F	0.785	0.64
64_F	466_H	0.777	0.63
61_A	65_I	0.776	0.63
562_F	595_I	0.774	0.63
308_E	499_I	0.773	0.63
362_G	579_N	0.772	0.63
231_R	298_L	0.769	0.62
357_G	383_V	0.768	0.62
60_I	439_N	0.768	0.62
385_N	388_L	0.767	0.62
520_G	593_T	0.766	0.62
24_V	535_I	0.765	0.62
164_E	530_V	0.764	0.62
166_L	172_G	0.763	0.62
365_L	372_E	0.762	0.62
49_F	444_I	0.761	0.61
241_M	380_I	0.761	0.61
306_L	370_A	0.760	0.61
22_G	585_F	0.760	0.61
235_I	307_L	0.757	0.61
66_I	107_A	0.754	0.61
540_A	545_V	0.753	0.61
43_L	560_A	0.751	0.60
171_H	183_L	0.751	0.60
99_M	473_I	0.747	0.60
193_M	592_F	0.746	0.60
188_L	537_L	0.744	0.60
57_V	473_I	0.744	0.60
233_L	307_L	0.743	0.60
340_K	344_E	0.741	0.59
191_L	194_L	0.741	0.59
114_V	141_S	0.741	0.59
27_D	468_P	0.741	0.59
509_L	601_V	0.740	0.59
173_F	548_Y	0.738	0.59
138_M	201_K	0.738	0.59
69_G	456_I	0.737	0.59
553_V	597_M	0.737	0.59
521_L	568_S	0.736	0.59
63_L	112_T	0.736	0.59
103_A	143_A	0.733	0.59
30_A	462_Y	0.731	0.58
63_L	161_V	0.730	0.58
134_S	204_T	0.729	0.58
497_M	542_T	0.727	0.58
260_I	371_D	0.727	0.58
481_V	484_Q	0.727	0.58
144_G	570_V	0.726	0.58
525_N	558_A	0.725	0.58
56_N	522_F	0.722	0.57
54_D	110_S	0.720	0.57
20_A	266_R	0.719	0.57
100_L	104_G	0.719	0.57
110_S	570_V	0.718	0.57
78_V	82_W	0.717	0.57
126_A	136_L	0.716	0.57
483_L	531_L	0.716	0.57
493_V	497_M	0.716	0.57
165_L	548_Y	0.714	0.57
446_A	470_I	0.713	0.56
199_M	608_F	0.712	0.56
556_M	600_C	0.711	0.56
126_A	133_P	0.710	0.56
397_R	403_N	0.707	0.56
475_G	479_F	0.707	0.56
27_D	474_V	0.706	0.56
462_Y	471_I	0.706	0.56
104_G	183_L	0.705	0.56
155_T	158_N	0.705	0.56
62_A	450_M	0.704	0.55
168_E	537_L	0.702	0.55
4_E	7_W	0.701	0.55
91_E	542_T	0.701	0.55
238_G	306_L	0.701	0.55
502_G	507_M	0.700	0.55
102_V	114_V	0.699	0.55
141_S	571_N	0.699	0.55
110_S	140_L	0.698	0.55
110_S	155_T	0.697	0.55
27_D	34_I	0.697	0.55
63_L	513_F	0.696	0.55
175_F	476_M	0.696	0.55
475_G	524_S	0.695	0.55
149_M	194_L	0.694	0.54
236_R	427_L	0.693	0.54
495_G	498_D	0.691	0.54
520_G	561_A	0.691	0.54
565_P	571_N	0.689	0.54
63_L	568_S	0.688	0.54
543_M	549_P	0.687	0.54
145_L	561_A	0.686	0.54
243_G	282_R	0.686	0.54
56_N	110_S	0.686	0.54
110_S	443_A	0.684	0.53
480_A	552_M	0.684	0.53
24_V	32_F	0.683	0.53
232_R	263_E	0.682	0.53
161_V	433_L	0.682	0.53
524_S	568_S	0.682	0.53
160_V	520_G	0.681	0.53
42_T	99_M	0.681	0.53
189_G	513_F	0.680	0.53
514_V	601_V	0.680	0.53
113_G	570_V	0.680	0.53
384_G	389_I	0.680	0.53
245_R	259_V	0.678	0.53
494_K	598_A	0.677	0.53
462_Y	478_P	0.677	0.53
127_M	356_V	0.677	0.53
599_V	603_M	0.677	0.53
34_I	475_G	0.677	0.53
61_A	64_F	0.675	0.52
31_L	34_I	0.674	0.52
191_L	209_R	0.674	0.52
63_L	593_T	0.673	0.52
141_S	157_P	0.670	0.52
513_F	553_V	0.669	0.52
99_M	198_F	0.669	0.52
428_M	432_M	0.668	0.52
126_A	130_Q	0.668	0.52
31_L	475_G	0.667	0.52
419_P	423_F	0.666	0.51
140_L	163_S	0.665	0.51
35_V	444_I	0.663	0.51
584_D	587_K	0.662	0.51
50_S	514_V	0.662	0.51
449_L	453_F	0.662	0.51
111_S	521_L	0.661	0.51
11_L	37_F	0.660	0.51
577_P	585_F	0.658	0.51
59_L	568_S	0.658	0.51
19_F	353_L	0.657	0.50
372_E	429_V	0.657	0.50
523_I	549_P	0.655	0.50
60_I	539_A	0.654	0.50
124_S	128_R	0.651	0.50
359_K	528_T	0.651	0.50
521_L	569_P	0.650	0.50
545_V	549_P	0.650	0.50
63_L	67_G	0.650	0.50
20_A	265_W	0.650	0.50
31_L	48_V	0.649	0.50
451_G	454_R	0.649	0.50
32_F	448_L	0.648	0.49
281_F	606_M	0.648	0.49
552_M	555_A	0.645	0.49
365_L	370_A	0.642	0.49
70_L	80_G	0.642	0.49
8_V	488_G	0.642	0.49
240_P	306_L	0.640	0.49
25_R	29_V	0.640	0.49
110_S	113_G	0.639	0.49
127_M	358_L	0.639	0.49
110_S	529_A	0.638	0.48
64_F	443_A	0.638	0.48
154_A	520_G	0.637	0.48
417_Q	421_A	0.637	0.48
331_L	399_F	0.637	0.48
286_V	289_I	0.636	0.48
409_S	412_S	0.636	0.48
242_I	280_E	0.636	0.48
13_A	36_A	0.635	0.48
57_V	60_I	0.635	0.48
21_T	24_V	0.634	0.48
117_I	585_F	0.634	0.48
52_F	292_S	0.634	0.48
184_V	598_A	0.633	0.48
57_V	165_L	0.633	0.48
138_M	540_A	0.632	0.48
481_V	485_K	0.632	0.48
526_T	569_P	0.629	0.47
585_F	588_L	0.629	0.47
8_V	482_A	0.629	0.47
36_A	594_I	0.628	0.47
242_I	542_T	0.628	0.47
341_S	347_F	0.627	0.47
289_I	298_L	0.626	0.47
556_M	575_L	0.626	0.47
529_A	558_A	0.625	0.47
420_H	604_I	0.625	0.47
473_I	560_A	0.625	0.47
396_G	400_V	0.624	0.47
34_I	48_V	0.624	0.47
110_S	114_V	0.623	0.47
54_D	532_M	0.622	0.47
506_H	510_G	0.622	0.47
343_R	353_L	0.622	0.47
166_L	171_H	0.622	0.47
12_L	479_F	0.622	0.47
437_I	442_A	0.622	0.47
145_L	568_S	0.622	0.47
25_R	555_A	0.622	0.47
422_I	427_L	0.620	0.46
131_T	136_L	0.620	0.46
59_L	521_L	0.620	0.46
95_L	194_L	0.619	0.46
100_L	195_V	0.619	0.46
545_V	605_P	0.619	0.46
102_V	192_Y	0.619	0.46
517_A	597_M	0.618	0.46
30_A	476_M	0.617	0.46
429_V	535_I	0.617	0.46
245_R	249_L	0.617	0.46
147_S	520_G	0.616	0.46
30_A	289_I	0.615	0.46
503_Y	587_K	0.614	0.46
79_M	554_V	0.613	0.46
375_L	463_K	0.609	0.45
185_V	463_K	0.609	0.45
504_G	511_C	0.609	0.45
17_V	338_I	0.609	0.45
404_L	408_V	0.608	0.45
37_F	80_G	0.608	0.45
18_L	29_V	0.607	0.45
551_A	593_T	0.606	0.45
99_M	194_L	0.605	0.45
474_V	478_P	0.605	0.45
37_F	42_T	0.605	0.45
191_L	431_L	0.605	0.45
570_V	574_V	0.604	0.45
24_V	475_G	0.604	0.45
299_R	357_G	0.603	0.45
192_Y	195_V	0.603	0.45
509_L	553_V	0.603	0.45
110_S	157_P	0.603	0.45
253_E	423_F	0.602	0.45
488_G	492_A	0.601	0.44
252_R	287_L	0.601	0.44
417_Q	420_H	0.600	0.44
17_V	238_G	0.600	0.44
231_R	259_V	0.599	0.44
568_S	585_F	0.599	0.44
386_W	432_M	0.599	0.44
289_I	388_L	0.599	0.44
188_L	281_F	0.598	0.44
145_L	521_L	0.597	0.44
13_A	238_G	0.597	0.44
73_T	421_A	0.597	0.44
556_M	568_S	0.596	0.44
178_V	516_S	0.596	0.44
593_T	596_V	0.595	0.44
413_P	460_S	0.595	0.44
473_I	551_A	0.594	0.44
141_S	144_G	0.594	0.44
471_I	475_G	0.593	0.44
481_V	557_A	0.593	0.44
552_M	556_M	0.592	0.44
360_R	365_L	0.591	0.43
571_N	585_F	0.591	0.43
44_T	431_L	0.590	0.43
67_G	552_M	0.589	0.43
419_P	422_I	0.589	0.43
508_M	545_V	0.588	0.43
110_S	559_S	0.588	0.43
521_L	559_S	0.588	0.43
121_V	562_F	0.587	0.43
39_L	245_R	0.587	0.43
157_P	524_S	0.587	0.43
490_A	581_S	0.587	0.43
49_F	513_F	0.587	0.43
437_I	449_L	0.586	0.43
146_I	573_L	0.586	0.43
475_G	481_V	0.585	0.43
195_V	588_L	0.585	0.43
61_A	471_I	0.585	0.43
567_S	608_F	0.585	0.43
159_L	460_S	0.584	0.43
156_P	164_E	0.584	0.43
64_F	425_L	0.584	0.43
375_L	416_S	0.584	0.43
536_A	540_A	0.584	0.43
175_F	460_S	0.584	0.43
531_L	570_V	0.583	0.43
142_F	521_L	0.582	0.42
566_V	571_N	0.582	0.42
106_G	567_S	0.582	0.42
287_L	365_L	0.581	0.42
24_V	492_A	0.581	0.42
230_A	345_I	0.581	0.42
11_L	45_V	0.581	0.42
507_M	510_G	0.580	0.42
195_V	198_F	0.580	0.42
162_N	173_F	0.580	0.42
178_V	556_M	0.580	0.42
252_R	348_R	0.580	0.42
396_G	401_A	0.578	0.42
335_S	462_Y	0.578	0.42
516_S	558_A	0.578	0.42
122_V	136_L	0.578	0.42
193_M	598_A	0.578	0.42
174_S	587_K	0.577	0.42
110_S	175_F	0.577	0.42
73_T	455_C	0.576	0.42
321_A	594_I	0.575	0.42
117_I	425_L	0.575	0.42
152_L	382_V	0.574	0.42
111_S	525_N	0.572	0.41
35_V	311_V	0.572	0.41
261_G	449_L	0.572	0.41
66_I	450_M	0.571	0.41
137_M	449_L	0.571	0.41
397_R	522_F	0.571	0.41
111_S	154_A	0.570	0.41
75_V	303_S	0.570	0.41
263_E	288_L	0.569	0.41
275_V	278_V	0.569	0.41
498_D	501_G	0.568	0.41
574_V	580_Y	0.568	0.41
319_D	594_I	0.568	0.41
446_A	556_M	0.564	0.41
19_F	231_R	0.562	0.40
11_L	479_F	0.561	0.40
427_L	576_G	0.561	0.40
59_L	439_N	0.561	0.40
234_A	242_I	0.560	0.40
115_V	141_S	0.560	0.40
529_A	574_V	0.560	0.40
109_M	117_I	0.560	0.40
106_G	520_G	0.559	0.40
169_G	172_G	0.558	0.40
59_L	567_S	0.558	0.40
106_G	525_N	0.558	0.40
70_L	506_H	0.557	0.40
331_L	340_K	0.555	0.40
141_S	567_S	0.553	0.39
55_P	440_P	0.553	0.39
250_K	254_R	0.552	0.39
113_G	354_N	0.552	0.39
571_N	582_F	0.552	0.39
357_G	410_E	0.552	0.39
76_A	156_P	0.552	0.39
120_P	584_D	0.551	0.39
149_M	559_S	0.551	0.39
423_F	607_L	0.551	0.39
16_I	454_R	0.551	0.39
140_L	145_L	0.551	0.39
155_T	178_V	0.551	0.39
114_V	570_V	0.550	0.39
568_S	575_L	0.550	0.39
22_G	546_S	0.550	0.39
82_W	436_E	0.549	0.39
7_W	459_E	0.549	0.39
476_M	572_T	0.548	0.39
58_V	512_L	0.547	0.39
69_G	402_L	0.547	0.39
262_V	281_F	0.547	0.39
206_T	538_A	0.545	0.39
336_E	398_D	0.544	0.39
19_F	472_L	0.544	0.39
105_L	118_F	0.543	0.38
483_L	561_A	0.542	0.38
113_G	432_M	0.542	0.38
128_R	581_S	0.542	0.38
556_M	570_V	0.542	0.38
359_K	531_L	0.541	0.38
575_L	585_F	0.541	0.38
428_M	556_M	0.541	0.38
564_T	571_N	0.541	0.38
15_A	579_N	0.541	0.38
54_D	142_F	0.541	0.38
425_L	429_V	0.540	0.38
526_T	570_V	0.540	0.38
119_I	585_F	0.540	0.38
196_M	492_A	0.540	0.38
389_I	392_L	0.540	0.38
281_F	342_V	0.539	0.38
598_A	602_V	0.539	0.38
427_L	498_D	0.539	0.38
13_A	93_K	0.539	0.38
60_I	567_S	0.539	0.38
68_D	71_V	0.538	0.38
520_G	526_T	0.538	0.38
496_L	515_L	0.537	0.38
25_R	462_Y	0.537	0.38
375_L	545_V	0.537	0.38
158_N	582_F	0.534	0.37
188_L	191_L	0.534	0.37
138_M	582_F	0.534	0.37
353_L	399_F	0.534	0.37
232_R	369_L	0.533	0.37
392_L	483_L	0.533	0.37
451_G	557_A	0.532	0.37
49_F	181_I	0.532	0.37
510_G	604_I	0.531	0.37
396_G	404_L	0.531	0.37
467_W	471_I	0.530	0.37
201_K	580_Y	0.530	0.37
63_L	159_L	0.530	0.37
183_L	506_H	0.529	0.37
180_P	556_M	0.529	0.37
135_R	198_F	0.529	0.37
92_I	316_Y	0.528	0.37
79_M	486_T	0.528	0.37
69_G	172_G	0.527	0.37
73_T	170_Y	0.526	0.37
245_R	355_V	0.526	0.37
295_D	300_Q	0.526	0.37
157_P	525_N	0.525	0.37
115_V	428_M	0.524	0.36
79_M	415_H	0.524	0.36
550_F	553_V	0.523	0.36
54_D	117_I	0.523	0.36
95_L	511_C	0.523	0.36
137_M	193_M	0.522	0.36
281_F	287_L	0.521	0.36
289_I	389_I	0.521	0.36
56_N	439_N	0.520	0.36
337_L	345_I	0.520	0.36
102_V	119_I	0.520	0.36
516_S	559_S	0.520	0.36
356_V	383_V	0.519	0.36
148_G	155_T	0.518	0.36
5_L	25_R	0.518	0.36
36_A	40_S	0.516	0.36
283_A	320_Q	0.516	0.36
357_G	371_D	0.516	0.36
98_L	140_L	0.515	0.36
115_V	513_F	0.515	0.36
145_L	560_A	0.514	0.36
506_H	587_K	0.514	0.36
204_T	209_R	0.514	0.36
70_L	468_P	0.514	0.36
173_F	551_A	0.514	0.36
11_L	318_S	0.514	0.36
194_L	606_M	0.513	0.35
247_D	356_V	0.513	0.35
5_L	8_V	0.512	0.35
443_A	526_T	0.512	0.35
158_N	178_V	0.512	0.35
291_M	362_G	0.512	0.35
426_V	494_K	0.512	0.35
439_N	526_T	0.511	0.35
9_L	520_G	0.510	0.35
39_L	537_L	0.509	0.35
256_G	295_D	0.509	0.35
249_L	252_R	0.509	0.35
20_A	391_M	0.509	0.35
248_D	445_I	0.508	0.35
346_G	496_L	0.508	0.35
156_P	520_G	0.508	0.35
5_L	67_G	0.508	0.35
552_M	585_F	0.508	0.35
7_W	14_V	0.508	0.35
60_I	232_R	0.508	0.35
145_L	149_M	0.508	0.35
59_L	469_S	0.505	0.35
63_L	110_S	0.505	0.35
263_E	368_S	0.505	0.35
498_D	544_G	0.505	0.35
355_V	370_A	0.505	0.35
138_M	144_G	0.504	0.35
188_L	603_M	0.504	0.35
456_I	461_A	0.504	0.35
57_V	470_I	0.503	0.34
19_F	467_W	0.503	0.34
342_V	347_F	0.503	0.34
520_G	524_S	0.502	0.34
110_S	566_V	0.501	0.34
458_A	465_I	0.500	0.34
69_G	447_C	0.500	0.34
10_S	246_L	0.500	0.34
110_S	569_P	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f35D	2	0.6689	100	0.707	Contact Map
4r1iA	2	0.7213	100	0.849	Contact Map
4r0cA	3	0.7115	99.9	0.881	Contact Map
4g65A	2	0.4885	99.7	0.903	Contact Map
4gx0A	3	0.6131	99.7	0.906	Contact Map
1vctA	3	0.2951	99.2	0.932	Contact Map
1lnqA	6	0.3967	99.1	0.933	Contact Map
3jxoA	4	0.1393	98.9	0.939	Contact Map
4xttA	2	0.1393	98.9	0.939	Contact Map
2aefA	2	0.3279	98.7	0.942	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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