GREMLIN Database
YCJO - Inner membrane ABC transporter permease protein YcjO
UniProt: P0AFR7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13912
Length: 293 (252)
Sequences: 69567 (44959)
Seq/√Len: 2832.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
206_Q210_I4.0411.00
74_W78_W3.2011.00
183_L187_Q2.9981.00
198_E207_R2.9901.00
40_S60_Y2.7461.00
72_S251_Y2.6501.00
71_H74_W2.5911.00
100_R194_Y2.5911.00
203_N206_Q2.5381.00
197_A207_R2.4941.00
82_L167_V2.4851.00
194_Y212_T2.4791.00
185_I219_V2.4591.00
86_G171_I2.4181.00
246_D254_K2.4071.00
58_S61_V2.3781.00
61_V65_S2.3661.00
70_W74_W2.3451.00
84_V224_V2.3201.00
204_A207_R2.2601.00
182_F220_L2.2251.00
205_W209_R2.2211.00
58_S62_R2.1821.00
102_F105_R2.1131.00
202_A206_Q2.0521.00
92_L208_F2.0431.00
206_Q209_R2.0431.00
261_D264_K2.0391.00
178_A223_V1.9561.00
99_N187_Q1.9521.00
186_L216_I1.9301.00
197_A202_A1.8881.00
193_L215_A1.8881.00
38_E42_L1.8821.00
92_L216_I1.8001.00
88_T224_V1.7881.00
109_R183_L1.7581.00
71_H75_M1.7381.00
34_V38_E1.7301.00
198_E204_A1.7291.00
80_T228_T1.7101.00
91_G178_A1.6971.00
194_Y207_R1.6871.00
281_L285_K1.6851.00
62_R264_K1.6381.00
78_W82_L1.6331.00
92_L182_F1.6271.00
83_V231_M1.6271.00
98_F179_F1.5821.00
94_V179_F1.5811.00
194_Y198_E1.5571.00
37_I270_V1.5311.00
191_K194_Y1.4771.00
19_A23_L1.4761.00
242_T245_V1.4621.00
101_E105_R1.4521.00
251_Y255_T1.4331.00
62_R65_S1.4291.00
57_V61_V1.4271.00
235_F239_Y1.4231.00
79_Y247_I1.4141.00
95_A182_F1.3991.00
104_L107_T1.3991.00
31_W35_S1.3991.00
178_A227_R1.3921.00
99_N183_L1.3891.00
213_L220_L1.3871.00
56_G59_N1.3831.00
35_S39_I1.3651.00
186_L212_T1.3481.00
222_T226_L1.3471.00
68_G71_H1.3351.00
87_S227_R1.3231.00
182_F223_V1.3061.00
89_V93_A1.2891.00
100_R191_K1.2831.00
191_K195_E1.2681.00
235_F253_Y1.2571.00
237_D241_L1.2491.00
92_L220_L1.2431.00
197_A211_V1.2411.00
192_S195_E1.2361.00
255_T259_F1.2191.00
169_F241_L1.2161.00
96_M186_L1.2041.00
76_T248_L1.2031.00
255_T261_D1.1981.00
131_F165_L1.1941.00
82_L85_A1.1911.00
85_A89_V1.1821.00
246_D251_Y1.1751.00
107_T110_S1.1641.00
189_I215_A1.1621.00
23_L27_G1.1551.00
13_F17_L1.1521.00
12_P16_L1.1351.00
203_N207_R1.1291.00
166_V238_V1.1241.00
217_M221_A1.1131.00
88_T220_L1.1131.00
75_M78_W1.1121.00
14_A18_L1.1031.00
285_K288_N1.0911.00
36_N270_V1.0861.00
182_F219_V1.0791.00
60_Y270_V1.0761.00
107_T111_L1.0631.00
167_V171_I1.0531.00
83_V87_S1.0481.00
254_K258_A1.0441.00
215_A218_P1.0431.00
64_L70_W1.0421.00
96_M208_F1.0421.00
234_M237_D1.0401.00
132_N135_Y1.0381.00
181_S223_V1.0361.00
282_L286_R1.0351.00
16_L20_P1.0291.00
82_L86_G1.0281.00
99_N186_L1.0261.00
86_G167_V1.0201.00
194_Y204_A1.0201.00
247_I250_V1.0181.00
77_V81_A1.0151.00
73_L248_L1.0081.00
141_L245_V1.0071.00
175_F179_F1.0061.00
13_F16_L1.0041.00
16_L19_A0.9971.00
93_A97_F0.9951.00
202_A207_R0.9931.00
129_Y133_N0.9921.00
251_Y268_I0.9901.00
83_V170_A0.9881.00
238_V247_I0.9831.00
256_A265_A0.9821.00
35_S38_E0.9821.00
234_M238_V0.9801.00
164_V168_L0.9801.00
96_M204_A0.9751.00
246_D250_V0.9621.00
78_W164_V0.9541.00
105_R187_Q0.9521.00
207_R210_I0.9411.00
15_L19_A0.9281.00
170_A231_M0.9241.00
137_I164_V0.9231.00
85_A224_V0.9211.00
69_F268_I0.9131.00
127_W241_L0.9121.00
59_N263_G0.9081.00
78_W81_A0.9081.00
239_Y250_V0.9031.00
81_A85_A0.8991.00
95_A99_N0.8961.00
26_G30_A0.8911.00
164_V167_V0.8911.00
39_I266_A0.8901.00
18_L22_L0.8901.00
103_R106_K0.8871.00
185_I216_I0.8801.00
83_V167_V0.8761.00
217_M220_L0.8751.00
216_I219_V0.8751.00
113_I180_I0.8721.00
63_I271_V0.8691.00
91_G179_F0.8691.00
40_S44_L0.8681.00
41_F55_V0.8671.00
178_A182_F0.8651.00
182_F216_I0.8611.00
62_R66_D0.8611.00
169_F237_D0.8611.00
79_Y170_A0.8601.00
39_I42_L0.8581.00
208_F213_L0.8571.00
209_R213_L0.8531.00
127_W169_F0.8521.00
87_S91_G0.8491.00
95_A179_F0.8441.00
73_L77_V0.8411.00
255_T268_I0.8391.00
98_F109_R0.8381.00
86_G89_V0.8381.00
106_K109_R0.8321.00
251_Y254_K0.8291.00
227_R231_M0.8291.00
120_S173_R0.8101.00
242_T246_D0.8051.00
276_I280_I0.8051.00
282_L285_K0.8011.00
207_R212_T0.8001.00
82_L171_I0.7961.00
138_V141_L0.7901.00
97_F102_F0.7881.00
74_W77_V0.7831.00
204_A208_F0.7831.00
36_N266_A0.7811.00
202_A210_I0.7801.00
124_V236_A0.7781.00
95_A186_L0.7781.00
51_E54_F0.7731.00
66_D70_W0.7701.00
278_A282_L0.7681.00
255_T264_K0.7671.00
193_L211_V0.7641.00
62_R261_D0.7631.00
72_S75_M0.7591.00
189_I216_I0.7581.00
87_S174_Y0.7571.00
137_I140_Y0.7561.00
136_G139_N0.7521.00
137_I141_L0.7521.00
128_K132_N0.7501.00
41_F56_G0.7491.00
264_K268_I0.7451.00
208_F212_T0.7441.00
124_V240_L0.7421.00
45_P48_P0.7381.00
39_I43_R0.7371.00
61_V64_L0.7341.00
165_L169_F0.7321.00
55_V58_S0.7281.00
72_S248_L0.7231.00
36_N269_S0.7231.00
113_I116_Y0.7231.00
87_S178_A0.7231.00
94_V175_F0.7221.00
31_W34_V0.7211.00
88_T182_F0.7211.00
80_T84_V0.7191.00
166_V242_T0.7151.00
98_F108_A0.7131.00
84_V228_T0.7121.00
252_L268_I0.7111.00
217_M286_R0.7081.00
20_P23_L0.7041.00
91_G182_F0.7041.00
76_T249_G0.7041.00
283_T286_R0.7031.00
67_P71_H0.7031.00
98_F183_L0.7031.00
182_F186_L0.7021.00
191_K198_E0.6981.00
43_R54_F0.6981.00
70_W73_L0.6961.00
234_M247_I0.6931.00
17_L21_S0.6911.00
220_L223_V0.6911.00
84_V88_T0.6901.00
25_L29_V0.6901.00
17_L20_P0.6901.00
266_A269_S0.6881.00
123_L172_W0.6861.00
165_L241_L0.6791.00
87_S231_M0.6791.00
120_S236_A0.6781.00
54_F58_S0.6771.00
248_L272_L0.6741.00
174_Y227_R0.6731.00
75_M245_V0.6691.00
43_R53_T0.6691.00
59_N62_R0.6681.00
266_A270_V0.6641.00
212_T215_A0.6641.00
42_L52_S0.6641.00
135_Y138_V0.6591.00
57_V60_Y0.6571.00
196_A199_M0.6571.00
90_L175_F0.6561.00
238_V250_V0.6551.00
26_G29_V0.6551.00
196_A200_D0.6541.00
220_L224_V0.6521.00
174_Y230_W0.6501.00
79_Y167_V0.6471.00
263_G266_A0.6471.00
63_I264_K0.6451.00
101_E106_K0.6431.00
94_V112_V0.6411.00
42_L54_F0.6391.00
272_L276_I0.6391.00
90_L171_I0.6381.00
250_V254_K0.6381.00
109_R180_I0.6371.00
22_L26_G0.6371.00
104_L108_A0.6361.00
40_S267_A0.6301.00
79_Y166_V0.6301.00
219_V223_V0.6301.00
12_P15_L0.6281.00
253_Y257_F0.6261.00
67_P70_W0.6261.00
249_G272_L0.6231.00
60_Y267_A0.6221.00
56_G60_Y0.6211.00
129_Y132_N0.6191.00
68_G251_Y0.6181.00
63_I268_I0.6181.00
102_F108_A0.6161.00
236_A240_L0.6161.00
262_L266_A0.6151.00
277_F281_L0.6101.00
170_A173_R0.6091.00
87_S171_I0.6061.00
54_F57_V0.6061.00
181_S219_V0.6051.00
132_N138_V0.6051.00
262_L265_A0.6031.00
121_I240_L0.6021.00
112_V176_P0.6011.00
229_I233_Y0.5991.00
21_S25_L0.5981.00
76_T232_F0.5911.00
15_L18_L0.5871.00
78_W141_L0.5861.00
116_Y176_P0.5851.00
80_T231_M0.5821.00
127_W130_M0.5741.00
42_L53_T0.5731.00
116_Y177_Y0.5731.00
40_S270_V0.5731.00
236_A239_Y0.5711.00
88_T92_L0.5711.00
103_R107_T0.5691.00
207_R211_V0.5651.00
264_K267_A0.5641.00
94_V97_F0.5631.00
203_N209_R0.5621.00
30_A34_V0.5621.00
189_I194_Y0.5611.00
221_A224_V0.5601.00
95_A183_L0.5591.00
96_M212_T0.5571.00
224_V227_R0.5561.00
209_R212_T0.5561.00
135_Y140_Y0.5551.00
80_T232_F0.5541.00
79_Y83_V0.5521.00
170_A234_M0.5511.00
166_V170_A0.5481.00
131_F138_V0.5471.00
130_M138_V0.5471.00
44_L52_S0.5451.00
230_W233_Y0.5431.00
75_M247_I0.5411.00
280_I284_R0.5411.00
275_I278_A0.5411.00
110_S114_L0.5391.00
108_A112_V0.5381.00
88_T93_A0.5371.00
106_K110_S0.5371.00
238_V242_T0.5351.00
27_G31_W0.5351.00
252_L269_S0.5341.00
101_E191_K0.5341.00
83_V171_I0.5341.00
173_R176_P0.5321.00
28_L32_P0.5301.00
250_V253_Y0.5291.00
84_V89_V0.5291.00
68_G246_D0.5281.00
78_W167_V0.5281.00
141_L164_V0.5261.00
19_A22_L0.5211.00
124_V128_K0.5171.00
120_S124_V0.5121.00
84_V231_M0.5111.00
231_M234_M0.5101.00
111_L115_S0.5101.00
118_T122_S0.5071.00
115_S176_P0.5071.00
195_E198_E0.5061.00
101_E104_L0.5051.00
69_F251_Y0.5051.00
71_H78_W0.5041.00
32_P36_N0.5011.00
170_A238_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.942 100 0.274 Contact Map
2onkC 2 0.8532 100 0.3 Contact Map
3d31C 2 0.843 100 0.312 Contact Map
3rlfF 1 0.9317 100 0.357 Contact Map
4tquN 1 0.8908 100 0.36 Contact Map
3rlfG 1 0.8976 100 0.369 Contact Map
4ymuD 2 0.727 99.9 0.517 Contact Map
3tuiA 2 0.7099 99.9 0.533 Contact Map
2a65A 2 0.7986 36.8 0.935 Contact Map
2m20A 2 0.1195 15.4 0.946 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0109 seconds.