PPX - ECOLI - GREMLIN Contacts

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PPX - Exopolyphosphatase

UniProt:	P0AFL6	Sequences: MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQRVHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFLKRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPILVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASGTIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLAILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQARRVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNSDLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEESTPEIAA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11403
Length:	513 (483)
Sequences:	2284 (1671)
Seq/√Len:	76.0

ECOLI - PPX GPPA
SULSO - Q97YV9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
345_E	360_E	6.411	1.00
85_C	114_E	4.734	1.00
424_F	427_F	4.461	1.00
356_H	359_L	3.766	1.00
56_M	96_L	3.732	1.00
341_M	360_E	3.675	1.00
63_T	67_N	3.594	1.00
106_E	112_P	3.552	1.00
39_G	447_N	3.522	1.00
173_A	273_P	3.521	1.00
385_S	409_V	3.485	1.00
142_I	281_V	3.484	1.00
219_T	274_G	3.470	1.00
87_V	301_V	3.450	1.00
105_A	113_I	3.229	1.00
421_L	424_F	3.177	1.00
220_I	278_L	3.144	1.00
359_L	431_Q	3.114	1.00
59_E	104_R	3.110	1.00
73_A	77_Q	3.043	1.00
389_L	409_V	3.034	1.00
76_L	84_V	2.942	1.00
195_A	280_G	2.863	1.00
52_G	56_M	2.829	1.00
137_G	155_E	2.770	1.00
493_W	497_A	2.712	1.00
337_L	364_R	2.702	1.00
341_M	345_E	2.692	1.00
226_V	271_F	2.650	1.00
381_L	412_H	2.609	1.00
384_H	387_Y	2.601	1.00
421_L	427_F	2.589	1.00
343_M	438_L	2.515	1.00
70_S	108_V	2.514	1.00
88_G	92_L	2.406	1.00
215_G	220_I	2.404	1.00
282_F	290_L	2.359	1.00
151_L	281_V	2.328	1.00
344_Y	360_E	2.322	1.00
315_R	397_F	2.296	1.00
98_A	115_I	2.257	1.00
120_E	123_R	2.253	1.00
376_I	388_I	2.219	1.00
236_I	289_E	2.195	1.00
423_R	427_F	2.155	1.00
18_L	113_I	2.153	1.00
59_E	63_T	2.140	1.00
86_I	111_Y	2.129	1.00
65_G	101_F	2.113	1.00
100_D	103_K	2.098	1.00
328_I	372_V	2.053	1.00
118_G	150_E	2.008	1.00
104_R	108_V	2.004	1.00
17_D	21_N	1.999	1.00
335_R	451_A	1.964	1.00
404_M	432_F	1.939	1.00
12_E	29_R	1.905	1.00
398_N	401_Q	1.899	1.00
14_A	76_L	1.897	1.00
101_F	105_A	1.894	1.00
105_A	109_I	1.882	1.00
195_A	283_D	1.878	1.00
243_E	279_C	1.862	1.00
99_T	103_K	1.842	1.00
319_A	369_L	1.830	1.00
190_A	194_A	1.806	1.00
243_E	283_D	1.801	1.00
197_K	200_T	1.785	1.00
28_A	302_L	1.775	1.00
57_L	101_F	1.774	1.00
62_M	97_N	1.770	1.00
421_L	425_T	1.735	1.00
59_E	100_D	1.722	1.00
92_L	101_F	1.720	1.00
114_E	120_E	1.712	1.00
337_L	368_M	1.691	1.00
18_L	23_F	1.684	1.00
227_L	241_R	1.671	1.00
89_T	93_R	1.667	1.00
226_V	263_L	1.662	1.00
14_A	84_V	1.661	1.00
382_H	413_R	1.640	1.00
332_Q	335_R	1.634	1.00
400_E	428_K	1.628	1.00
123_R	304_E	1.620	1.00
339_T	446_N	1.618	1.00
58_S	61_A	1.605	1.00
265_E	268_K	1.605	1.00
239_P	243_E	1.603	1.00
27_I	79_F	1.594	0.99
21_N	267_R	1.587	0.99
198_L	281_V	1.579	0.99
322_L	372_V	1.573	0.99
21_N	218_G	1.560	0.99
142_I	290_L	1.560	0.99
24_H	296_A	1.558	0.99
84_V	111_Y	1.551	0.99
459_T	470_R	1.549	0.99
249_V	271_F	1.526	0.99
323_A	328_I	1.524	0.99
176_Y	193_A	1.510	0.99
191_R	280_G	1.509	0.99
125_I	217_S	1.499	0.99
412_H	443_V	1.487	0.99
466_H	502_K	1.474	0.99
76_L	81_P	1.472	0.99
94_Q	171_S	1.463	0.99
233_K	399_Q	1.456	0.99
147_G	171_S	1.450	0.99
104_R	107_K	1.446	0.99
118_G	122_A	1.443	0.99
365_W	397_F	1.442	0.99
132_T	295_G	1.439	0.99
462_T	467_W	1.433	0.99
494_E	500_R	1.407	0.99
17_D	218_G	1.394	0.99
253_R	256_A	1.388	0.99
195_A	284_A	1.386	0.99
142_I	213_A	1.386	0.99
227_L	231_G	1.372	0.98
227_L	235_G	1.369	0.98
150_E	164_S	1.368	0.98
102_L	115_I	1.368	0.98
143_D	148_S	1.361	0.98
218_G	267_R	1.349	0.98
11_Q	83_S	1.343	0.98
217_S	296_A	1.324	0.98
145_G	148_S	1.314	0.98
29_R	36_Q	1.304	0.98
143_D	267_R	1.299	0.98
351_Q	467_W	1.289	0.98
346_Q	460_L	1.288	0.98
239_P	283_D	1.286	0.98
26_V	299_E	1.282	0.98
347_W	351_Q	1.282	0.98
411_Y	417_K	1.273	0.97
430_K	434_P	1.271	0.97
315_R	365_W	1.270	0.97
337_L	341_M	1.263	0.97
185_E	189_R	1.260	0.97
467_W	493_W	1.255	0.97
351_Q	354_L	1.255	0.97
137_G	212_V	1.249	0.97
437_Q	493_W	1.249	0.97
103_K	107_K	1.247	0.97
243_E	247_K	1.244	0.97
22_S	42_K	1.240	0.97
87_V	297_L	1.236	0.97
194_A	276_A	1.231	0.97
332_Q	446_N	1.230	0.97
46_H	269_T	1.229	0.97
463_D	466_H	1.229	0.97
11_Q	82_A	1.225	0.97
230_M	248_E	1.221	0.97
237_I	242_L	1.220	0.97
169_C	270_V	1.211	0.97
246_V	275_L	1.205	0.96
123_R	127_M	1.204	0.96
92_L	105_A	1.194	0.96
191_R	283_D	1.191	0.96
63_T	104_R	1.190	0.96
213_A	282_F	1.180	0.96
18_L	88_G	1.180	0.96
24_H	217_S	1.179	0.96
90_H	171_S	1.177	0.96
23_F	65_G	1.174	0.96
218_G	298_R	1.163	0.96
41_L	75_R	1.156	0.96
23_F	72_F	1.149	0.95
341_M	364_R	1.146	0.95
249_V	275_L	1.144	0.95
122_A	150_E	1.139	0.95
483_L	487_E	1.132	0.95
137_G	211_N	1.132	0.95
188_Q	191_R	1.125	0.95
12_E	81_P	1.125	0.95
358_Q	401_Q	1.124	0.95
347_W	438_L	1.123	0.95
466_H	500_R	1.122	0.95
183_N	186_N	1.109	0.94
149_T	387_Y	1.103	0.94
142_I	149_T	1.103	0.94
479_N	482_V	1.099	0.94
17_D	24_H	1.092	0.94
463_D	468_T	1.091	0.94
246_V	250_L	1.088	0.94
461_I	468_T	1.087	0.94
342_Q	346_Q	1.080	0.94
319_A	365_W	1.076	0.93
269_T	272_V	1.075	0.93
324_N	330_S	1.075	0.93
165_R	201_L	1.070	0.93
323_A	368_M	1.069	0.93
404_M	408_L	1.065	0.93
62_M	101_F	1.065	0.93
239_P	279_C	1.062	0.93
46_H	270_V	1.059	0.93
21_N	24_H	1.059	0.93
61_A	95_A	1.057	0.93
304_E	308_R	1.049	0.93
43_Q	71_L	1.049	0.93
61_A	97_N	1.048	0.93
224_H	235_G	1.038	0.92
148_S	267_R	1.037	0.92
216_A	293_S	1.036	0.92
51_L	91_T	1.032	0.92
180_G	186_N	1.029	0.92
362_L	404_M	1.028	0.92
371_E	381_L	1.022	0.92
205_F	209_G	1.021	0.92
334_R	338_D	1.013	0.91
446_N	451_A	1.012	0.91
143_D	218_G	1.010	0.91
369_L	389_L	1.006	0.91
131_H	157_F	1.002	0.91
172_F	194_A	0.999	0.91
26_V	88_G	0.999	0.91
150_E	218_G	0.997	0.91
211_N	288_R	0.996	0.91
381_L	385_S	0.996	0.91
244_K	248_E	0.995	0.90
41_L	71_L	0.991	0.90
133_Q	214_M	0.990	0.90
74_E	77_Q	0.983	0.90
69_L	111_Y	0.983	0.90
461_I	470_R	0.980	0.90
73_A	111_Y	0.975	0.90
27_I	39_G	0.974	0.90
187_F	276_A	0.972	0.89
24_H	298_R	0.972	0.89
16_V	389_L	0.970	0.89
338_D	459_T	0.966	0.89
65_G	92_L	0.963	0.89
316_S	364_R	0.961	0.89
24_H	302_L	0.960	0.89
66_L	105_A	0.960	0.89
154_G	217_S	0.960	0.89
12_E	38_I	0.958	0.89
143_D	146_G	0.957	0.89
170_V	270_V	0.957	0.89
386_A	403_L	0.956	0.89
16_V	86_I	0.954	0.89
22_S	150_E	0.949	0.88
362_L	432_F	0.945	0.88
184_K	247_K	0.942	0.88
318_T	394_L	0.940	0.88
122_A	143_D	0.939	0.88
85_C	305_M	0.936	0.88
66_L	101_F	0.934	0.87
21_N	150_E	0.932	0.87
62_M	104_R	0.932	0.87
382_H	412_H	0.931	0.87
267_R	298_R	0.930	0.87
217_S	315_R	0.930	0.87
21_N	121_E	0.929	0.87
42_K	150_E	0.928	0.87
217_S	221_K	0.928	0.87
119_N	162_V	0.927	0.87
351_Q	434_P	0.926	0.87
247_K	251_R	0.926	0.87
256_A	259_S	0.924	0.87
332_Q	336_V	0.923	0.87
233_K	236_I	0.921	0.87
376_I	384_H	0.919	0.87
42_K	46_H	0.919	0.87
383_R	420_D	0.917	0.86
143_D	164_S	0.912	0.86
64_R	68_C	0.910	0.86
254_N	268_K	0.909	0.86
390_Q	403_L	0.906	0.86
137_G	156_N	0.903	0.86
143_D	150_E	0.902	0.86
95_A	98_A	0.896	0.85
323_A	333_A	0.895	0.85
148_S	164_S	0.894	0.85
118_G	145_G	0.894	0.85
93_R	150_E	0.891	0.85
363_L	435_L	0.890	0.85
88_G	416_I	0.890	0.85
124_L	304_E	0.889	0.85
370_H	447_N	0.888	0.85
121_E	218_G	0.887	0.85
90_H	147_G	0.887	0.85
18_L	45_V	0.887	0.85
279_C	283_D	0.883	0.84
146_G	267_R	0.880	0.84
151_L	201_L	0.880	0.84
17_D	20_S	0.876	0.84
358_Q	361_A	0.875	0.84
240_E	286_A	0.863	0.83
293_S	299_E	0.859	0.83
65_G	105_A	0.859	0.83
93_R	147_G	0.857	0.83
468_T	502_K	0.854	0.82
191_R	279_C	0.853	0.82
460_L	467_W	0.850	0.82
122_A	144_I	0.849	0.82
223_A	275_L	0.847	0.82
223_A	413_R	0.846	0.82
332_Q	449_R	0.846	0.82
461_I	464_D	0.845	0.82
48_A	171_S	0.844	0.82
17_D	145_G	0.844	0.82
198_L	284_A	0.840	0.81
92_L	115_I	0.838	0.81
22_S	274_G	0.838	0.81
386_A	406_A	0.837	0.81
348_R	357_P	0.836	0.81
363_L	439_L	0.834	0.81
410_R	417_K	0.832	0.81
70_S	107_K	0.832	0.81
275_L	279_C	0.832	0.81
354_L	359_L	0.830	0.80
28_A	35_M	0.829	0.80
16_V	108_V	0.827	0.80
360_E	364_R	0.825	0.80
351_Q	462_T	0.824	0.80
17_D	89_T	0.824	0.80
146_G	300_G	0.822	0.80
129_V	406_A	0.820	0.80
17_D	150_E	0.819	0.80
122_A	267_R	0.818	0.80
383_R	412_H	0.818	0.80
191_R	246_V	0.817	0.79
443_V	489_E	0.815	0.79
16_V	73_A	0.815	0.79
326_Y	375_N	0.813	0.79
227_L	245_L	0.813	0.79
46_H	170_V	0.812	0.79
79_F	84_V	0.810	0.79
435_L	438_L	0.806	0.79
56_M	100_D	0.806	0.79
118_G	219_T	0.805	0.78
29_R	38_I	0.804	0.78
239_P	290_L	0.804	0.78
268_K	272_V	0.803	0.78
335_R	339_T	0.802	0.78
203_W	212_V	0.802	0.78
22_S	219_T	0.802	0.78
42_K	118_G	0.801	0.78
122_A	145_G	0.795	0.78
129_V	141_V	0.794	0.77
121_E	143_D	0.792	0.77
223_A	278_L	0.791	0.77
17_D	146_G	0.790	0.77
253_R	257_S	0.789	0.77
328_I	333_A	0.787	0.77
24_H	218_G	0.784	0.77
394_L	398_N	0.783	0.76
123_R	149_T	0.782	0.76
337_L	340_T	0.781	0.76
170_V	274_G	0.780	0.76
92_L	98_A	0.779	0.76
93_R	143_D	0.777	0.76
121_E	267_R	0.773	0.76
254_N	258_L	0.772	0.75
206_R	286_A	0.772	0.75
30_V	35_M	0.771	0.75
118_G	274_G	0.771	0.75
320_S	324_N	0.767	0.75
250_L	253_R	0.767	0.75
17_D	298_R	0.766	0.75
122_A	148_S	0.765	0.75
146_G	164_S	0.764	0.75
76_L	171_S	0.761	0.74
125_I	216_A	0.761	0.74
87_V	116_I	0.760	0.74
145_G	267_R	0.760	0.74
61_A	64_R	0.758	0.74
146_G	150_E	0.757	0.74
282_F	287_I	0.756	0.74
80_S	350_Q	0.755	0.74
50_G	65_G	0.755	0.74
293_S	372_V	0.753	0.74
242_L	282_F	0.751	0.73
286_A	468_T	0.751	0.73
25_M	40_R	0.750	0.73
122_A	219_T	0.750	0.73
318_T	395_P	0.749	0.73
122_A	218_G	0.745	0.73
443_V	449_R	0.743	0.73
118_G	143_D	0.743	0.73
14_A	19_G	0.743	0.73
47_L	91_T	0.743	0.73
373_G	385_S	0.741	0.72
345_E	348_R	0.739	0.72
145_G	150_E	0.739	0.72
66_L	109_I	0.739	0.72
125_I	150_E	0.739	0.72
150_E	298_R	0.737	0.72
231_G	241_R	0.736	0.72
267_R	296_A	0.736	0.72
179_G	186_N	0.735	0.72
125_I	152_V	0.734	0.72
338_D	342_Q	0.734	0.72
86_I	113_I	0.733	0.72
122_A	162_V	0.733	0.72
28_A	299_E	0.733	0.72
340_T	363_L	0.733	0.72
263_L	282_F	0.731	0.71
36_Q	321_S	0.729	0.71
21_N	219_T	0.728	0.71
43_Q	68_C	0.728	0.71
21_N	298_R	0.727	0.71
42_K	143_D	0.727	0.71
122_A	146_G	0.726	0.71
294_D	379_S	0.726	0.71
155_E	160_I	0.725	0.71
58_S	62_M	0.723	0.71
282_F	285_L	0.721	0.70
17_D	122_A	0.719	0.70
27_I	361_A	0.718	0.70
23_F	45_V	0.716	0.70
128_G	303_Y	0.714	0.70
221_K	403_L	0.713	0.70
18_L	51_L	0.713	0.70
21_N	128_G	0.711	0.69
372_V	388_I	0.710	0.69
89_T	121_E	0.710	0.69
121_E	150_E	0.706	0.69
146_G	298_R	0.706	0.69
48_A	94_Q	0.706	0.69
463_D	500_R	0.705	0.69
399_Q	402_Q	0.705	0.69
219_T	267_R	0.704	0.69
118_G	146_G	0.704	0.69
382_H	414_K	0.704	0.69
385_S	408_L	0.704	0.69
459_T	466_H	0.703	0.68
373_G	388_I	0.701	0.68
21_N	42_K	0.701	0.68
383_R	410_R	0.701	0.68
25_M	76_L	0.700	0.68
120_E	124_L	0.700	0.68
37_I	40_R	0.696	0.68
59_E	66_L	0.696	0.68
120_E	304_E	0.695	0.68
31_V	36_Q	0.694	0.67
457_T	472_P	0.694	0.67
326_Y	392_S	0.694	0.67
280_G	283_D	0.694	0.67
21_N	143_D	0.693	0.67
364_R	368_M	0.692	0.67
385_S	412_H	0.691	0.67
194_A	280_G	0.690	0.67
425_T	428_K	0.690	0.67
187_F	194_A	0.690	0.67
404_M	431_Q	0.689	0.67
98_A	102_L	0.688	0.67
97_N	147_G	0.687	0.67
167_M	277_I	0.686	0.67
149_T	277_I	0.685	0.66
17_D	22_S	0.685	0.66
326_Y	376_I	0.684	0.66
362_L	401_Q	0.684	0.66
18_L	25_M	0.680	0.66
252_H	257_S	0.680	0.66
373_G	384_H	0.679	0.66
61_A	72_F	0.678	0.66
125_I	274_G	0.677	0.66
221_K	296_A	0.675	0.65
153_I	208_Q	0.673	0.65
232_E	244_K	0.671	0.65
22_S	118_G	0.669	0.65
88_G	115_I	0.669	0.65
223_A	242_L	0.669	0.65
89_T	164_S	0.668	0.65
167_M	198_L	0.668	0.65
21_N	122_A	0.667	0.64
142_I	278_L	0.665	0.64
60_E	459_T	0.665	0.64
102_L	108_V	0.665	0.64
142_I	220_I	0.664	0.64
332_Q	451_A	0.664	0.64
24_H	40_R	0.664	0.64
119_N	197_K	0.664	0.64
336_V	439_L	0.664	0.64
24_H	221_K	0.663	0.64
128_G	295_G	0.663	0.64
100_D	104_R	0.662	0.64
17_D	93_R	0.660	0.64
86_I	108_V	0.660	0.64
145_G	218_G	0.660	0.64
93_R	267_R	0.657	0.63
249_V	258_L	0.654	0.63
219_T	226_V	0.653	0.63
125_I	128_G	0.652	0.63
140_L	370_H	0.652	0.63
16_V	29_R	0.652	0.63
343_M	469_L	0.651	0.63
91_T	143_D	0.650	0.62
119_N	163_E	0.649	0.62
118_G	148_S	0.649	0.62
316_S	320_S	0.648	0.62
381_L	443_V	0.646	0.62
221_K	379_S	0.644	0.62
242_L	246_V	0.642	0.61
14_A	442_G	0.641	0.61
93_R	148_S	0.639	0.61
134_P	250_L	0.637	0.61
145_G	274_G	0.637	0.61
215_G	278_L	0.633	0.60
131_H	395_P	0.632	0.60
55_N	94_Q	0.632	0.60
336_V	442_G	0.631	0.60
136_K	247_K	0.631	0.60
21_N	164_S	0.629	0.60
88_G	307_G	0.628	0.60
252_H	258_L	0.626	0.60
268_K	409_V	0.625	0.59
73_A	82_A	0.625	0.59
340_T	435_L	0.624	0.59
16_V	289_E	0.624	0.59
121_E	146_G	0.624	0.59
25_M	39_G	0.623	0.59
91_T	148_S	0.621	0.59
408_L	469_L	0.621	0.59
62_M	66_L	0.620	0.59
118_G	164_S	0.619	0.59
238_T	241_R	0.619	0.59
366_A	405_M	0.619	0.59
334_R	337_L	0.618	0.59
163_E	201_L	0.616	0.58
170_V	214_M	0.616	0.58
24_H	299_E	0.615	0.58
206_R	209_G	0.613	0.58
145_G	164_S	0.613	0.58
71_L	75_R	0.610	0.58
22_S	65_G	0.609	0.57
58_S	72_F	0.607	0.57
393_D	397_F	0.606	0.57
341_M	349_E	0.603	0.57
186_N	498_G	0.602	0.57
390_Q	406_A	0.601	0.56
336_V	340_T	0.601	0.56
490_Q	494_E	0.600	0.56
118_G	278_L	0.599	0.56
102_L	453_T	0.599	0.56
55_N	86_I	0.598	0.56
254_N	257_S	0.598	0.56
60_E	102_L	0.598	0.56
422_P	427_F	0.597	0.56
167_M	172_F	0.597	0.56
17_D	267_R	0.595	0.56
273_P	388_I	0.595	0.56
414_K	446_N	0.594	0.56
188_Q	463_D	0.592	0.55
144_I	149_T	0.592	0.55
26_V	221_K	0.591	0.55
214_M	488_K	0.591	0.55
125_I	296_A	0.590	0.55
73_A	108_V	0.588	0.55
125_I	146_G	0.588	0.55
384_H	439_L	0.587	0.55
320_S	334_R	0.587	0.55
32_D	38_I	0.586	0.55
199_E	284_A	0.586	0.55
117_S	199_E	0.584	0.54
185_E	461_I	0.584	0.54
275_L	303_Y	0.583	0.54
20_S	217_S	0.583	0.54
64_R	274_G	0.582	0.54
89_T	143_D	0.581	0.54
373_G	435_L	0.581	0.54
117_S	290_L	0.580	0.54
239_P	282_F	0.579	0.54
15_A	154_G	0.579	0.54
67_N	198_L	0.579	0.54
313_D	361_A	0.579	0.54
461_I	466_H	0.579	0.54
187_F	279_C	0.578	0.54
116_I	124_L	0.577	0.53
164_S	218_G	0.576	0.53
481_L	484_L	0.575	0.53
17_D	300_G	0.573	0.53
273_P	277_I	0.573	0.53
461_I	465_S	0.573	0.53
193_A	197_K	0.572	0.53
90_H	410_R	0.572	0.53
246_V	279_C	0.572	0.53
122_A	164_S	0.572	0.53
344_Y	351_Q	0.572	0.53
106_E	109_I	0.572	0.53
373_G	401_Q	0.570	0.53
141_V	152_V	0.570	0.53
12_E	213_A	0.569	0.52
219_T	268_K	0.569	0.52
344_Y	363_L	0.568	0.52
244_K	463_D	0.567	0.52
88_G	223_A	0.567	0.52
26_V	40_R	0.567	0.52
75_R	481_L	0.566	0.52
320_S	330_S	0.566	0.52
177_F	190_A	0.565	0.52
52_G	58_S	0.565	0.52
146_G	218_G	0.564	0.52
39_G	75_R	0.564	0.52
295_G	299_E	0.563	0.52
90_H	94_Q	0.562	0.52
240_E	338_D	0.562	0.52
63_T	425_T	0.562	0.52
226_V	319_A	0.560	0.51
288_R	349_E	0.560	0.51
148_S	218_G	0.559	0.51
101_F	274_G	0.558	0.51
191_R	239_P	0.558	0.51
45_V	65_G	0.556	0.51
21_N	148_S	0.556	0.51
142_I	225_E	0.556	0.51
14_A	17_D	0.555	0.51
367_A	442_G	0.555	0.51
99_T	106_E	0.554	0.51
380_G	383_R	0.554	0.51
93_R	121_E	0.554	0.51
158_E	240_E	0.553	0.50
118_G	121_E	0.553	0.50
50_G	61_A	0.553	0.50
58_S	251_R	0.551	0.50
139_K	221_K	0.551	0.50
93_R	218_G	0.547	0.50
86_I	109_I	0.547	0.50
139_K	212_V	0.546	0.50
214_M	291_R	0.546	0.50
188_Q	283_D	0.546	0.50
23_F	217_S	0.545	0.49
207_I	283_D	0.545	0.49
242_L	279_C	0.545	0.49
309_F	362_L	0.545	0.49
351_Q	359_L	0.544	0.49
61_A	65_G	0.544	0.49
113_I	245_L	0.544	0.49
42_K	318_T	0.543	0.49
491_E	494_E	0.542	0.49
294_D	378_H	0.542	0.49
125_I	297_L	0.542	0.49
42_K	218_G	0.542	0.49
29_R	334_R	0.542	0.49
17_D	164_S	0.540	0.49
71_L	378_H	0.540	0.49
76_L	111_Y	0.539	0.49
281_V	465_S	0.539	0.49
17_D	297_L	0.538	0.48
160_I	208_Q	0.538	0.48
48_A	91_T	0.537	0.48
27_I	155_E	0.536	0.48
127_M	157_F	0.536	0.48
161_L	209_G	0.536	0.48
183_N	342_Q	0.536	0.48
158_E	341_M	0.535	0.48
86_I	488_K	0.535	0.48
251_R	457_T	0.535	0.48
460_L	463_D	0.535	0.48
119_N	166_R	0.534	0.48
494_E	501_L	0.533	0.48
186_N	189_R	0.533	0.48
398_N	453_T	0.533	0.48
377_N	447_N	0.532	0.48
114_E	128_G	0.532	0.48
42_K	172_F	0.531	0.48
28_A	37_I	0.530	0.47
153_I	211_N	0.530	0.47
387_Y	391_N	0.529	0.47
45_V	64_R	0.529	0.47
468_T	500_R	0.529	0.47
332_Q	371_E	0.528	0.47
190_A	449_R	0.528	0.47
39_G	292_L	0.527	0.47
227_L	233_K	0.526	0.47
381_L	402_Q	0.526	0.47
156_N	495_G	0.526	0.47
303_Y	395_P	0.526	0.47
323_A	441_L	0.525	0.47
336_V	370_H	0.524	0.47
342_Q	470_R	0.524	0.47
453_T	457_T	0.523	0.47
90_H	150_E	0.523	0.47
89_T	297_L	0.523	0.47
146_G	219_T	0.522	0.46
89_T	147_G	0.522	0.46
15_A	217_S	0.521	0.46
140_L	210_W	0.520	0.46
109_I	152_V	0.520	0.46
23_F	296_A	0.519	0.46
334_R	405_M	0.519	0.46
217_S	233_K	0.519	0.46
464_D	467_W	0.519	0.46
323_A	330_S	0.519	0.46
121_E	298_R	0.519	0.46
90_H	294_D	0.519	0.46
177_F	315_R	0.518	0.46
18_L	301_V	0.518	0.46
94_Q	166_R	0.518	0.46
137_G	208_Q	0.517	0.46
283_D	457_T	0.517	0.46
27_I	237_I	0.516	0.46
27_I	60_E	0.515	0.46
327_H	375_N	0.515	0.46
143_D	300_G	0.514	0.45
460_L	469_L	0.514	0.45
155_E	262_G	0.514	0.45
457_T	466_H	0.514	0.45
170_V	394_L	0.513	0.45
150_E	267_R	0.512	0.45
190_A	372_V	0.512	0.45
411_Y	436_I	0.512	0.45
134_P	157_F	0.511	0.45
465_S	498_G	0.511	0.45
62_M	201_L	0.510	0.45
401_Q	404_M	0.509	0.45
329_D	382_H	0.509	0.45
435_L	439_L	0.508	0.45
303_Y	313_D	0.508	0.45
71_L	440_R	0.507	0.45
214_M	255_F	0.507	0.45
130_E	134_P	0.505	0.44
18_L	65_G	0.504	0.44
154_G	315_R	0.504	0.44
63_T	232_E	0.503	0.44
142_I	291_R	0.503	0.44
108_V	111_Y	0.503	0.44
476_F	480_A	0.503	0.44
91_T	95_A	0.501	0.44
263_L	271_F	0.501	0.44
269_T	486_L	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1u6zA	2	0.9708	100	0.127	Contact Map
3hi0A	2	0.9415	100	0.215	Contact Map
3cerA	1	0.5984	100	0.499	Contact Map
1t6cA	1	0.5828	100	0.505	Contact Map
3mdqA	1	0.5906	100	0.511	Contact Map
4brcA	2	0.5848	100	0.663	Contact Map
3rf0A	1	0.386	100	0.698	Contact Map
3cj1A	1	0.6199	100	0.756	Contact Map
3zx3A	3	0.5789	100	0.762	Contact Map
3h1qA	1	0.46	99.7	0.872	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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