PMBA - ECOLI - GREMLIN Contacts

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PMBA - Metalloprotease PmbA

UniProt:	P0AFK0	Sequences: MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARYTSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEGGSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSARKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGAAGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10741
Length:	450 (423)
Sequences:	4579 (2979)
Seq/√Len:	144.8

ECOLI - PMBA TLDD
SULSO - TLDD Q97YZ8 Q97YZ7 Q7LXP5 Q97ZU9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
320_K	325_T	4.171	1.00
317_D	320_K	3.981	1.00
369_T	398_E	3.923	1.00
294_H	315_R	3.731	1.00
371_L	406_V	3.654	1.00
283_Q	287_D	3.583	1.00
423_V	443_P	3.455	1.00
243_K	444_E	3.409	1.00
368_G	399_N	3.370	1.00
423_V	441_L	3.256	1.00
367_M	397_V	3.186	1.00
359_S	362_Q	3.146	1.00
133_S	136_E	3.038	1.00
398_E	403_Q	3.037	1.00
237_R	404_Y	2.999	1.00
143_R	220_E	2.996	1.00
279_S	282_K	2.971	1.00
396_W	404_Y	2.849	1.00
398_E	404_Y	2.707	1.00
154_R	197_E	2.609	1.00
369_T	396_W	2.549	1.00
139_E	143_R	2.532	1.00
42_K	169_V	2.413	1.00
182_Y	305_P	2.389	1.00
24_T	86_P	2.339	1.00
363_M	439_S	2.325	1.00
396_W	403_Q	2.290	1.00
77_G	96_A	2.288	1.00
428_D	439_S	2.281	1.00
359_S	427_N	2.260	1.00
196_E	199_G	2.221	1.00
290_T	317_D	2.194	1.00
225_D	228_R	2.155	1.00
364_L	397_V	2.078	1.00
292_E	354_A	2.075	1.00
283_Q	420_R	2.052	1.00
292_E	315_R	2.001	1.00
146_Q	150_Q	1.985	1.00
288_W	425_V	1.985	1.00
28_L	90_A	1.983	1.00
358_L	362_Q	1.959	1.00
314_E	340_K	1.933	1.00
155_I	195_A	1.915	1.00
288_W	321_D	1.886	1.00
287_D	321_D	1.880	1.00
23_S	27_E	1.860	1.00
290_T	321_D	1.828	1.00
90_A	94_Q	1.819	1.00
244_A	447_I	1.819	1.00
304_T	313_T	1.814	1.00
206_A	225_D	1.796	1.00
171_V	179_L	1.794	1.00
365_K	401_E	1.789	1.00
224_A	228_R	1.783	1.00
195_A	231_L	1.767	1.00
363_M	424_T	1.760	1.00
228_R	232_S	1.746	1.00
151_A	224_A	1.742	1.00
418_M	442_L	1.722	1.00
285_L	419_W	1.722	1.00
195_A	230_T	1.721	1.00
283_Q	323_I	1.714	1.00
247_I	367_M	1.700	1.00
360_F	439_S	1.692	1.00
329_L	339_L	1.692	1.00
83_D	88_A	1.691	1.00
180_Q	306_F	1.682	1.00
94_Q	98_D	1.674	1.00
366_E	424_T	1.670	1.00
29_A	36_A	1.630	1.00
22_V	173_G	1.625	1.00
85_S	88_A	1.624	1.00
36_A	175_S	1.612	1.00
397_V	403_Q	1.602	1.00
387_D	414_N	1.601	1.00
355_G	429_I	1.597	1.00
151_A	227_A	1.587	1.00
137_A	163_F	1.582	1.00
147_A	223_G	1.567	1.00
367_M	441_L	1.564	1.00
197_E	235_S	1.562	1.00
421_N	444_E	1.561	1.00
316_R	344_H	1.554	1.00
75_R	105_P	1.550	1.00
272_K	277_L	1.541	1.00
70_V	96_A	1.538	1.00
329_L	333_S	1.530	1.00
72_H	101_R	1.527	1.00
372_V	397_V	1.524	1.00
139_E	142_A	1.523	1.00
334_A	340_K	1.516	1.00
147_A	220_E	1.513	1.00
50_T	55_V	1.491	1.00
417_D	421_N	1.486	1.00
395_F	402_I	1.481	1.00
366_E	441_L	1.479	1.00
316_R	326_Q	1.477	1.00
155_I	231_L	1.477	1.00
195_A	234_L	1.472	1.00
421_N	443_P	1.472	1.00
245_P	441_L	1.471	1.00
136_E	139_E	1.462	1.00
414_N	417_D	1.462	1.00
91_R	94_Q	1.457	1.00
245_P	443_P	1.443	1.00
304_T	349_H	1.443	1.00
66_L	81_S	1.441	1.00
197_E	200_D	1.435	1.00
360_F	364_L	1.434	1.00
169_V	181_G	1.433	1.00
315_R	352_R	1.432	1.00
42_K	64_G	1.417	1.00
261_V	351_W	1.412	1.00
247_I	363_M	1.403	1.00
370_G	397_V	1.401	1.00
358_L	424_T	1.390	1.00
253_A	440_V	1.381	1.00
148_A	223_G	1.380	1.00
24_T	27_E	1.377	1.00
135_D	139_E	1.368	1.00
269_V	327_W	1.356	1.00
318_I	328_L	1.347	1.00
329_L	337_L	1.346	1.00
249_A	372_V	1.339	1.00
28_L	31_G	1.334	1.00
87_Q	91_R	1.334	1.00
285_L	289_L	1.324	1.00
173_G	179_L	1.320	1.00
156_T	196_E	1.319	1.00
279_S	416_K	1.312	1.00
142_A	146_Q	1.306	1.00
247_I	441_L	1.306	1.00
217_Q	221_W	1.299	1.00
145_E	149_L	1.294	1.00
137_A	165_S	1.290	1.00
169_V	183_C	1.288	1.00
52_Y	157_N	1.286	1.00
292_E	317_D	1.266	1.00
311_V	341_S	1.265	1.00
281_G	325_T	1.263	1.00
264_I	318_I	1.262	1.00
358_L	366_E	1.248	1.00
147_A	224_A	1.242	1.00
37_E	69_T	1.237	1.00
270_Y	337_L	1.233	1.00
72_H	100_A	1.231	1.00
212_A	299_K	1.228	1.00
138_I	142_A	1.222	1.00
212_A	215_D	1.222	1.00
202_E	407_S	1.217	1.00
23_S	179_L	1.217	1.00
289_L	425_V	1.214	1.00
321_D	325_T	1.213	1.00
296_H	313_T	1.189	1.00
361_E	401_E	1.186	1.00
361_E	365_K	1.182	1.00
371_L	409_I	1.180	1.00
223_G	227_A	1.179	1.00
141_A	161_G	1.175	1.00
317_D	321_D	1.170	1.00
360_F	363_M	1.170	1.00
352_R	436_Q	1.165	1.00
208_T	222_V	1.164	1.00
315_R	354_A	1.160	1.00
425_V	440_V	1.158	1.00
155_I	227_A	1.158	1.00
431_T	436_Q	1.155	1.00
372_V	402_I	1.153	1.00
37_E	174_N	1.153	1.00
48_V	55_V	1.150	1.00
53_G	145_E	1.148	0.99
46_I	137_A	1.148	0.99
317_D	325_T	1.145	0.99
426_G	439_S	1.143	0.99
79_A	92_T	1.139	0.99
73_Q	105_P	1.134	0.99
72_H	97_L	1.133	0.99
163_F	189_L	1.129	0.99
290_T	354_A	1.128	0.99
364_L	372_V	1.126	0.99
311_V	343_G	1.112	0.99
221_W	225_D	1.112	0.99
382_S	387_D	1.103	0.99
290_T	320_K	1.100	0.99
247_I	397_V	1.097	0.99
148_A	193_V	1.097	0.99
334_A	341_S	1.097	0.99
193_V	227_A	1.092	0.99
280_L	339_L	1.087	0.99
28_L	94_Q	1.084	0.99
311_V	331_S	1.081	0.99
239_L	244_A	1.076	0.99
245_P	444_E	1.075	0.99
87_Q	90_A	1.074	0.99
257_F	353_I	1.074	0.99
26_L	38_V	1.074	0.99
237_R	396_W	1.074	0.99
247_I	360_F	1.068	0.99
243_K	446_K	1.067	0.99
154_R	231_L	1.062	0.99
26_L	36_A	1.060	0.99
167_Y	183_C	1.060	0.99
266_G	329_L	1.056	0.99
326_Q	342_T	1.055	0.99
352_R	429_I	1.050	0.99
204_D	226_C	1.047	0.99
406_V	409_I	1.044	0.99
360_F	427_N	1.039	0.99
42_K	62_S	1.035	0.99
196_E	201_M	1.030	0.99
418_M	445_M	1.030	0.99
363_M	426_G	1.028	0.99
26_L	175_S	1.022	0.99
195_A	227_A	1.020	0.99
227_A	231_L	1.019	0.99
215_D	299_K	1.018	0.99
291_I	319_I	1.018	0.99
417_D	420_R	1.011	0.99
74_N	105_P	1.007	0.99
291_I	351_W	0.996	0.99
24_T	28_L	0.996	0.99
143_R	146_Q	0.996	0.99
46_I	165_S	0.987	0.98
174_N	178_M	0.986	0.98
360_F	428_D	0.984	0.98
35_G	176_H	0.982	0.98
88_A	92_T	0.981	0.98
288_W	358_L	0.980	0.98
65_A	78_S	0.979	0.98
121_A	124_L	0.977	0.98
220_E	224_A	0.976	0.98
286_P	425_V	0.975	0.98
329_L	341_S	0.974	0.98
382_S	385_T	0.972	0.98
50_T	142_A	0.965	0.98
24_T	90_A	0.965	0.98
367_M	370_G	0.964	0.98
91_R	95_A	0.964	0.98
29_A	33_S	0.958	0.98
259_H	263_A	0.953	0.98
295_P	304_T	0.948	0.98
388_Y	418_M	0.947	0.98
68_I	92_T	0.942	0.98
275_F	416_K	0.939	0.98
364_L	367_M	0.938	0.98
114_K	117_L	0.934	0.98
362_Q	365_K	0.928	0.98
289_L	422_I	0.923	0.98
244_A	396_W	0.922	0.98
215_D	218_T	0.921	0.98
29_A	32_K	0.916	0.98
303_S	350_N	0.914	0.97
316_R	342_T	0.910	0.97
358_L	427_N	0.908	0.97
213_M	216_L	0.908	0.97
358_L	363_M	0.908	0.97
253_A	437_C	0.908	0.97
22_V	38_V	0.903	0.97
424_T	441_L	0.901	0.97
190_S	205_Y	0.900	0.97
38_V	66_L	0.894	0.97
295_P	349_H	0.891	0.97
379_Q	390_R	0.891	0.97
71_Y	76_K	0.886	0.97
248_F	373_V	0.883	0.97
81_S	92_T	0.881	0.97
40_V	66_L	0.879	0.97
25_A	89_I	0.876	0.97
226_C	230_T	0.874	0.97
360_F	372_V	0.874	0.97
295_P	313_T	0.873	0.97
289_L	353_I	0.872	0.97
147_A	150_Q	0.872	0.97
370_G	402_I	0.870	0.97
44_T	62_S	0.866	0.97
143_R	147_A	0.865	0.96
272_K	278_D	0.864	0.96
373_V	411_I	0.863	0.96
118_A	121_A	0.863	0.96
31_G	94_Q	0.858	0.96
30_S	175_S	0.853	0.96
285_L	319_I	0.848	0.96
397_V	402_I	0.842	0.96
22_V	40_V	0.842	0.96
144_A	189_L	0.842	0.96
171_V	181_G	0.841	0.96
148_A	226_C	0.838	0.96
33_S	70_V	0.836	0.96
154_R	234_L	0.830	0.96
81_S	88_A	0.829	0.96
35_G	172_F	0.828	0.95
41_S	168_G	0.827	0.95
309_E	331_S	0.825	0.95
376_L	380_G	0.825	0.95
344_H	349_H	0.824	0.95
55_V	138_I	0.821	0.95
172_F	180_Q	0.818	0.95
361_E	364_L	0.818	0.95
364_L	402_I	0.818	0.95
381_V	390_R	0.816	0.95
260_L	285_L	0.815	0.95
240_S	369_T	0.815	0.95
242_M	369_T	0.814	0.95
367_M	423_V	0.814	0.95
148_A	227_A	0.810	0.95
297_L	300_G	0.806	0.95
97_L	101_R	0.806	0.95
110_G	335_R	0.801	0.95
33_S	72_H	0.800	0.95
51_R	56_E	0.799	0.95
295_P	316_R	0.798	0.94
206_A	222_V	0.798	0.94
221_W	224_A	0.796	0.94
108_C	111_V	0.793	0.94
93_V	97_L	0.792	0.94
328_L	348_I	0.792	0.94
259_H	262_G	0.790	0.94
193_V	230_T	0.789	0.94
257_F	291_I	0.789	0.94
49_S	57_N	0.788	0.94
401_E	404_Y	0.784	0.94
297_L	352_R	0.783	0.94
147_A	151_A	0.776	0.94
395_F	405_P	0.776	0.94
116_L	340_K	0.775	0.94
112_A	115_E	0.774	0.94
247_I	372_V	0.772	0.93
237_R	398_E	0.771	0.93
348_I	351_W	0.770	0.93
44_T	167_Y	0.770	0.93
363_M	367_M	0.764	0.93
261_V	419_W	0.761	0.93
364_L	369_T	0.759	0.93
49_S	162_S	0.758	0.93
252_V	255_G	0.757	0.93
259_H	390_R	0.756	0.93
35_G	175_S	0.755	0.93
140_L	213_M	0.753	0.93
139_E	146_Q	0.752	0.93
245_P	369_T	0.751	0.93
270_Y	329_L	0.750	0.92
202_E	233_R	0.748	0.92
236_P	407_S	0.745	0.92
330_T	333_S	0.743	0.92
176_H	331_S	0.743	0.92
69_T	309_E	0.742	0.92
270_Y	333_S	0.741	0.92
29_A	70_V	0.741	0.92
239_L	371_L	0.741	0.92
329_L	334_A	0.738	0.92
22_V	26_L	0.738	0.92
115_E	340_K	0.737	0.92
293_E	316_R	0.737	0.92
64_G	84_L	0.736	0.92
79_A	96_A	0.735	0.92
140_L	143_R	0.734	0.92
285_L	422_I	0.733	0.92
260_L	263_A	0.732	0.92
224_A	227_A	0.728	0.91
244_A	371_L	0.726	0.91
264_I	324_L	0.722	0.91
246_V	445_M	0.721	0.91
112_A	116_L	0.720	0.91
238_K	408_E	0.719	0.91
88_A	91_R	0.715	0.91
352_R	431_T	0.715	0.91
113_D	176_H	0.713	0.90
170_K	182_Y	0.712	0.90
231_L	234_L	0.711	0.90
374_T	395_F	0.709	0.90
388_Y	413_G	0.708	0.90
151_A	231_L	0.706	0.90
132_V	136_E	0.705	0.90
429_I	436_Q	0.701	0.90
127_F	167_Y	0.700	0.90
47_S	59_E	0.698	0.90
295_P	303_S	0.697	0.89
283_Q	321_D	0.695	0.89
120_D	123_D	0.693	0.89
422_I	440_V	0.693	0.89
258_G	347_G	0.692	0.89
359_S	426_G	0.692	0.89
45_G	164_N	0.691	0.89
257_F	289_L	0.690	0.89
252_V	376_L	0.690	0.89
40_V	64_G	0.688	0.89
225_D	229_R	0.687	0.89
91_R	98_D	0.686	0.89
52_Y	149_L	0.684	0.89
244_A	406_V	0.683	0.88
193_V	226_C	0.682	0.88
248_F	376_L	0.681	0.88
394_G	406_V	0.680	0.88
147_A	227_A	0.678	0.88
371_L	396_W	0.677	0.88
206_A	226_C	0.674	0.88
112_A	311_V	0.674	0.88
381_V	415_L	0.673	0.88
307_D	343_G	0.673	0.88
77_G	100_A	0.668	0.87
265_A	268_S	0.668	0.87
165_S	187_H	0.667	0.87
258_G	348_I	0.665	0.87
48_V	134_P	0.665	0.87
320_K	323_I	0.664	0.87
214_S	217_Q	0.664	0.87
269_V	274_T	0.664	0.87
47_S	162_S	0.662	0.87
313_T	349_H	0.662	0.87
253_A	353_I	0.661	0.87
286_P	289_L	0.661	0.87
25_A	31_G	0.661	0.87
364_L	368_G	0.659	0.87
66_L	89_I	0.655	0.86
294_H	352_R	0.653	0.86
276_L	324_L	0.652	0.86
136_E	140_L	0.651	0.86
257_F	440_V	0.650	0.86
31_G	97_L	0.650	0.86
39_A	170_K	0.649	0.86
376_L	390_R	0.646	0.86
356_Q	438_G	0.646	0.86
314_E	326_Q	0.645	0.86
264_I	319_I	0.644	0.85
321_D	340_K	0.644	0.85
259_H	348_I	0.643	0.85
397_V	441_L	0.643	0.85
267_G	271_R	0.642	0.85
37_E	67_G	0.640	0.85
256_L	376_L	0.640	0.85
363_M	441_L	0.639	0.85
266_G	337_L	0.639	0.85
132_V	137_A	0.639	0.85
43_T	166_H	0.638	0.85
378_G	413_G	0.638	0.85
332_Y	336_K	0.636	0.85
258_G	262_G	0.636	0.85
77_G	99_I	0.636	0.85
115_E	118_A	0.636	0.85
331_S	335_R	0.633	0.84
94_Q	224_A	0.630	0.84
297_L	303_S	0.628	0.84
128_H	131_E	0.628	0.84
43_T	168_G	0.628	0.84
127_F	131_E	0.627	0.84
372_V	439_S	0.626	0.84
380_G	389_S	0.626	0.84
204_D	230_T	0.625	0.84
33_S	36_A	0.624	0.84
229_R	249_A	0.622	0.83
23_S	30_S	0.620	0.83
378_G	389_S	0.619	0.83
265_A	348_I	0.616	0.83
333_S	337_L	0.616	0.83
208_T	212_A	0.614	0.83
239_L	242_M	0.614	0.83
213_M	217_Q	0.609	0.82
365_K	369_T	0.609	0.82
96_A	100_A	0.608	0.82
357_G	427_N	0.607	0.82
399_N	403_Q	0.607	0.82
168_G	184_S	0.605	0.82
421_N	445_M	0.604	0.82
208_T	217_Q	0.603	0.81
274_T	327_W	0.600	0.81
356_Q	427_N	0.598	0.81
252_V	373_V	0.598	0.81
37_E	78_S	0.598	0.81
278_D	282_K	0.598	0.81
363_M	402_I	0.597	0.81
110_G	113_D	0.597	0.81
113_D	117_L	0.596	0.81
263_A	347_G	0.596	0.81
280_L	327_W	0.595	0.81
209_I	301_L	0.595	0.81
437_C	440_V	0.595	0.81
245_P	367_M	0.594	0.81
81_S	89_I	0.594	0.81
66_L	84_L	0.592	0.80
308_S	346_G	0.590	0.80
334_A	339_L	0.589	0.80
282_K	323_I	0.589	0.80
369_T	399_N	0.588	0.80
124_L	128_H	0.587	0.80
285_L	291_I	0.585	0.80
366_E	399_N	0.585	0.80
132_V	213_M	0.584	0.79
391_G	408_E	0.584	0.79
231_L	235_S	0.582	0.79
39_A	168_G	0.581	0.79
380_G	390_R	0.581	0.79
368_G	403_Q	0.580	0.79
265_A	379_Q	0.578	0.79
376_L	379_Q	0.578	0.79
284_I	420_R	0.578	0.79
28_L	93_V	0.576	0.78
58_V	142_A	0.575	0.78
255_G	259_H	0.575	0.78
217_Q	225_D	0.575	0.78
44_T	169_V	0.574	0.78
159_E	192_C	0.574	0.78
200_D	235_S	0.574	0.78
392_A	409_I	0.573	0.78
162_S	190_S	0.572	0.78
50_T	141_A	0.572	0.78
114_K	178_M	0.571	0.78
137_A	141_A	0.570	0.78
378_G	410_T	0.570	0.78
266_G	270_Y	0.570	0.78
232_S	395_F	0.570	0.78
86_P	90_A	0.569	0.78
52_Y	158_T	0.568	0.78
255_G	378_G	0.567	0.77
145_E	161_G	0.567	0.77
377_M	410_T	0.566	0.77
270_Y	336_K	0.566	0.77
260_L	419_W	0.566	0.77
99_I	327_W	0.565	0.77
369_T	403_Q	0.564	0.77
303_S	349_H	0.564	0.77
426_G	438_G	0.564	0.77
70_V	93_V	0.564	0.77
262_G	383_A	0.563	0.77
150_Q	224_A	0.563	0.77
249_A	374_T	0.562	0.77
416_K	420_R	0.562	0.77
39_A	78_S	0.561	0.77
148_A	158_T	0.561	0.77
144_A	191_S	0.560	0.77
296_H	315_R	0.559	0.76
258_G	263_A	0.558	0.76
133_S	139_E	0.557	0.76
357_G	424_T	0.556	0.76
280_L	326_Q	0.555	0.76
389_S	412_A	0.555	0.76
70_V	100_A	0.554	0.76
114_K	118_A	0.554	0.76
386_G	414_N	0.553	0.76
100_A	103_T	0.553	0.76
235_S	405_P	0.552	0.75
275_F	419_W	0.552	0.75
70_V	77_G	0.552	0.75
242_M	447_I	0.551	0.75
126_L	129_P	0.551	0.75
263_A	348_I	0.550	0.75
291_I	353_I	0.549	0.75
33_S	97_L	0.549	0.75
366_E	423_V	0.549	0.75
148_A	191_S	0.548	0.75
268_S	383_A	0.548	0.75
237_R	403_Q	0.547	0.75
143_R	218_T	0.547	0.75
355_G	427_N	0.547	0.75
318_I	351_W	0.546	0.75
45_G	166_H	0.546	0.75
107_P	115_E	0.545	0.75
45_G	63_D	0.543	0.74
55_V	58_V	0.543	0.74
26_L	29_A	0.542	0.74
65_A	80_S	0.541	0.74
94_Q	105_P	0.541	0.74
270_Y	278_D	0.541	0.74
262_G	347_G	0.541	0.74
66_L	88_A	0.540	0.74
351_W	437_C	0.540	0.74
353_I	440_V	0.540	0.74
389_S	410_T	0.539	0.74
228_R	231_L	0.538	0.74
255_G	390_R	0.538	0.74
321_D	354_A	0.538	0.74
39_A	65_A	0.537	0.74
158_T	193_V	0.537	0.74
300_G	303_S	0.536	0.73
265_A	330_T	0.535	0.73
261_V	348_I	0.535	0.73
235_S	401_E	0.535	0.73
330_T	345_A	0.535	0.73
329_L	342_T	0.534	0.73
67_G	78_S	0.532	0.73
259_H	347_G	0.532	0.73
362_Q	366_E	0.531	0.73
259_H	381_V	0.531	0.73
223_G	230_T	0.531	0.73
120_D	181_G	0.531	0.73
31_G	90_A	0.530	0.73
141_A	163_F	0.529	0.72
271_R	385_T	0.529	0.72
26_L	173_G	0.528	0.72
121_A	305_P	0.528	0.72
360_F	367_M	0.527	0.72
255_G	261_V	0.525	0.72
44_T	60_F	0.524	0.72
392_A	411_I	0.524	0.72
217_Q	224_A	0.522	0.71
245_P	368_G	0.522	0.71
111_V	114_K	0.520	0.71
272_K	279_S	0.520	0.71
365_K	368_G	0.519	0.71
391_G	410_T	0.518	0.71
292_E	352_R	0.518	0.71
380_G	410_T	0.516	0.71
367_M	372_V	0.516	0.71
132_V	196_E	0.515	0.70
127_F	130_A	0.514	0.70
48_V	137_A	0.513	0.70
29_A	175_S	0.513	0.70
45_G	61_N	0.513	0.70
155_I	230_T	0.512	0.70
392_A	414_N	0.512	0.70
291_I	422_I	0.511	0.70
248_F	253_A	0.511	0.70
153_K	224_A	0.511	0.70
330_T	341_S	0.510	0.70
254_T	430_E	0.510	0.70
33_S	100_A	0.509	0.70
47_S	164_N	0.509	0.70
352_R	355_G	0.507	0.69
69_T	76_K	0.507	0.69
366_E	397_V	0.507	0.69
374_T	402_I	0.506	0.69
264_I	328_L	0.506	0.69
25_A	86_P	0.506	0.69
206_A	229_R	0.505	0.69
280_L	325_T	0.505	0.69
116_L	123_D	0.504	0.69
247_I	364_L	0.504	0.69
26_L	30_S	0.504	0.69
328_L	351_W	0.504	0.69
61_N	282_K	0.503	0.69
69_T	78_S	0.503	0.69
207_Y	211_R	0.502	0.68
29_A	97_L	0.502	0.68
286_P	290_T	0.501	0.68
25_A	28_L	0.500	0.68

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qtdA	2	0.98	100	0.08	Contact Map
3tv9A	2	0.9689	100	0.097	Contact Map
1vpbA	2	0.96	100	0.119	Contact Map
1vl4A	2	0.9378	100	0.137	Contact Map
3u1kA	3	0.2133	10.6	0.974	Contact Map
2zp1A	2	0.2467	8.9	0.974	Contact Map
2plgA	4	0.3133	6	0.976	Contact Map
1jg8A	4	0.2267	5.2	0.977	Contact Map
1v5sA	1	0.2556	5	0.977	Contact Map
1im3D	1	0.1244	4.9	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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