PHOB - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

PHOB - Phosphate regulon transcriptional regulatory protein PhoB

UniProt:	P0AFJ5	Sequences: MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10728
Length:	229 (209)
Sequences:	73847 (53114)
Seq/√Len:	3673.9

ECOLI - PHOB CUSR PHOP YEDW QSEB CREB TORR ARCA BASR BAER OMPR RSTA KDPE CPXR UVRY EVGA YHJB FIMZ DCUR NARP YJJQ NARL DPIA YGEK RCSB BGLJ RCSA UHPA BARA TORS CSGD RCSC RSSB ARCB YPDB YEHT CHEB EVGS NTRC GLRR ZRAR ATOC RCSD CHEY
BACSU - PHOP YYCF YXDJ CSSR YVRH YRKP YVCP YCBL BCER YKOG YCLJ CITT RESD YFIK CMPA YXJL DCTR LIAR MALR YBDJ YVFU YDFI YHCZ DEGU DESR YESN GLNL LYTT CHEB NATR SP0A CHEV CHEY SP0F CCDB
HALSA - CHEB Q9HR09 Q9HNM3 Q9HRE5 BAT O51970 F2Z6H5 Q9HP91

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
15_R	31_E	3.692	1.00
15_R	33_E	3.258	1.00
19_C	31_E	3.173	1.00
72_S	75_R	2.779	1.00
8_V	38_A	2.729	1.00
39_V	67_H	2.615	1.00
36_D	58_G	2.607	1.00
35_Y	59_G	2.422	1.00
59_G	67_H	2.421	1.00
34_D	58_G	2.418	1.00
43_N	71_E	2.414	1.00
30_V	47_P	2.394	1.00
4_R	30_V	2.200	1.00
4_R	28_Q	2.110	1.00
21_V	109_P	2.066	1.00
32_A	41_Q	2.041	1.00
19_C	23_E	2.029	1.00
91_R	111_E	1.994	1.00
33_E	37_S	1.887	1.00
65_I	79_V	1.882	1.00
25_N	113_V	1.856	1.00
55_M	85_R	1.847	1.00
52_L	64_F	1.835	1.00
193_R	196_D	1.814	1.00
81_M	94_G	1.792	1.00
158_T	161_K	1.769	1.00
88_E	108_S	1.753	1.00
34_D	37_S	1.741	1.00
6_L	32_A	1.701	1.00
69_K	100_D	1.686	1.00
81_M	99_A	1.682	1.00
30_V	41_Q	1.641	1.00
67_H	71_E	1.630	1.00
136_G	149_G	1.612	1.00
60_S	63_Q	1.601	1.00
59_G	63_Q	1.596	1.00
41_Q	45_P	1.591	1.00
164_H	168_T	1.557	1.00
35_Y	64_F	1.519	1.00
176_R	196_D	1.517	1.00
30_V	45_P	1.513	1.00
165_F	182_H	1.496	1.00
67_H	70_R	1.495	1.00
22_L	116_I	1.490	1.00
41_Q	44_E	1.485	1.00
42_L	68_L	1.479	1.00
101_D	115_R	1.474	1.00
198_H	201_R	1.438	1.00
65_I	81_M	1.435	1.00
85_R	90_D	1.432	1.00
36_D	59_G	1.415	1.00
3_R	120_M	1.401	1.00
80_V	119_V	1.401	1.00
63_Q	66_K	1.395	1.00
50_I	77_I	1.384	1.00
49_L	116_I	1.363	1.00
199_I	203_R	1.349	1.00
100_D	122_R	1.331	1.00
39_V	64_F	1.320	1.00
54_W	81_M	1.311	1.00
174_Y	182_H	1.310	1.00
9_E	15_R	1.304	1.00
66_K	97_T	1.291	1.00
54_W	62_I	1.281	1.00
52_L	65_I	1.269	1.00
10_D	53_D	1.259	1.00
39_V	59_G	1.252	1.00
12_A	33_E	1.248	1.00
41_Q	47_P	1.240	1.00
8_V	56_L	1.236	1.00
40_N	44_E	1.220	1.00
165_F	169_H	1.218	1.00
133_E	138_S	1.215	1.00
37_S	40_N	1.191	1.00
140_D	143_S	1.185	1.00
175_S	178_Q	1.177	1.00
37_S	41_Q	1.172	1.00
27_F	117_K	1.161	1.00
87_E	90_D	1.160	1.00
36_D	40_N	1.158	1.00
4_R	45_P	1.157	1.00
6_L	38_A	1.141	1.00
100_D	119_V	1.139	1.00
32_A	38_A	1.136	1.00
6_L	47_P	1.124	1.00
96_E	117_K	1.121	1.00
113_V	117_K	1.118	1.00
62_I	93_R	1.116	1.00
159_E	205_A	1.107	1.00
26_G	117_K	1.106	1.00
66_K	93_R	1.106	1.00
72_S	77_I	1.088	1.00
145_R	152_P	1.082	1.00
139_L	167_M	1.078	1.00
25_N	117_K	1.064	1.00
88_E	92_V	1.062	1.00
38_A	64_F	1.060	1.00
165_F	174_Y	1.060	1.00
6_L	41_Q	1.059	1.00
111_E	114_A	1.054	1.00
197_V	200_R	1.052	1.00
160_F	164_H	1.038	1.00
138_S	147_M	1.035	1.00
194_T	198_H	1.034	1.00
161_K	164_H	1.024	1.00
62_I	94_G	1.024	1.00
5_I	27_F	1.020	1.00
208_P	217_T	1.014	1.00
89_E	93_R	1.012	1.00
16_E	31_E	1.009	1.00
6_L	42_L	1.008	1.00
178_Q	182_H	1.006	1.00
49_L	120_M	1.003	1.00
39_V	43_N	0.996	1.00
93_R	97_T	0.994	1.00
114_A	118_A	0.986	1.00
3_R	27_F	0.985	1.00
62_I	97_T	0.979	1.00
144_H	221_T	0.969	1.00
141_P	164_H	0.968	1.00
91_R	104_T	0.967	1.00
42_L	72_S	0.965	1.00
32_A	37_S	0.965	1.00
38_A	42_L	0.964	1.00
177_E	192_D	0.962	1.00
50_I	68_L	0.959	1.00
92_V	96_E	0.951	1.00
8_V	50_I	0.945	1.00
18_V	82_L	0.938	1.00
13_P	17_M	0.924	1.00
119_V	122_R	0.919	1.00
8_V	32_A	0.916	1.00
52_L	81_M	0.915	1.00
65_I	97_T	0.912	1.00
157_P	161_K	0.909	1.00
12_A	16_E	0.908	1.00
3_R	124_S	0.908	1.00
209_G	212_D	0.905	1.00
52_L	79_V	0.905	1.00
63_Q	67_H	0.904	1.00
19_C	29_P	0.899	1.00
193_R	197_V	0.898	1.00
88_E	91_R	0.898	1.00
7_V	18_V	0.893	1.00
86_G	104_T	0.888	1.00
193_R	200_R	0.888	1.00
174_Y	178_Q	0.879	1.00
40_N	43_N	0.879	1.00
54_W	60_S	0.876	1.00
147_M	152_P	0.874	1.00
65_I	99_A	0.874	1.00
78_P	100_D	0.869	1.00
56_L	64_F	0.866	1.00
93_R	96_E	0.862	1.00
7_V	29_P	0.862	1.00
201_R	204_K	0.854	1.00
50_I	79_V	0.854	1.00
133_E	136_G	0.851	1.00
139_L	160_F	0.849	1.00
4_R	47_P	0.846	1.00
165_F	179_L	0.837	1.00
27_F	113_V	0.835	1.00
46_W	72_S	0.832	1.00
131_V	138_S	0.832	1.00
12_A	15_R	0.825	1.00
92_V	110_K	0.822	1.00
51_L	112_L	0.817	1.00
208_P	213_R	0.816	1.00
20_F	24_Q	0.814	1.00
16_E	19_C	0.813	1.00
66_K	70_R	0.810	1.00
54_W	90_D	0.803	1.00
51_L	82_L	0.794	1.00
18_V	112_L	0.789	1.00
42_L	47_P	0.781	1.00
64_F	68_L	0.776	1.00
118_A	121_R	0.774	1.00
80_V	115_R	0.771	1.00
200_R	204_K	0.771	1.00
139_L	146_V	0.770	1.00
4_R	48_D	0.769	1.00
55_M	84_A	0.768	1.00
192_D	196_D	0.767	1.00
54_W	85_R	0.765	1.00
118_A	123_I	0.760	1.00
59_G	64_F	0.754	1.00
109_P	113_V	0.752	1.00
177_E	181_N	0.747	1.00
207_E	213_R	0.742	1.00
95_L	115_R	0.741	1.00
68_L	75_R	0.741	1.00
90_D	93_R	0.741	1.00
111_E	115_R	0.736	1.00
89_E	110_K	0.735	1.00
108_S	111_E	0.729	1.00
107_F	112_L	0.727	1.00
209_G	213_R	0.725	1.00
217_T	221_T	0.722	1.00
8_V	64_F	0.721	1.00
42_L	77_I	0.717	1.00
35_Y	39_V	0.714	1.00
144_H	161_K	0.709	1.00
80_V	101_D	0.705	1.00
147_M	150_E	0.702	1.00
7_V	19_C	0.701	1.00
156_G	205_A	0.701	1.00
39_V	42_L	0.699	1.00
82_L	107_F	0.696	1.00
101_D	118_A	0.690	1.00
136_G	140_D	0.690	1.00
43_N	72_S	0.686	1.00
16_E	20_F	0.686	1.00
202_L	205_A	0.683	1.00
110_K	114_A	0.680	1.00
7_V	31_E	0.679	1.00
71_E	75_R	0.678	1.00
72_S	76_D	0.677	1.00
68_L	79_V	0.677	1.00
35_Y	58_G	0.676	1.00
42_L	50_I	0.675	1.00
165_F	168_T	0.674	1.00
168_T	182_H	0.673	1.00
3_R	48_D	0.672	1.00
120_M	123_I	0.672	1.00
178_Q	181_N	0.667	1.00
96_E	114_A	0.667	1.00
148_A	151_E	0.666	1.00
9_E	56_L	0.665	1.00
197_V	201_R	0.663	1.00
195_V	199_I	0.663	1.00
43_N	67_H	0.660	1.00
88_E	110_K	0.659	1.00
94_G	99_A	0.655	1.00
17_M	21_V	0.654	1.00
78_P	126_M	0.652	1.00
136_G	148_A	0.652	1.00
76_D	126_M	0.648	1.00
199_I	202_L	0.646	1.00
15_R	19_C	0.646	1.00
212_D	215_V	0.642	1.00
162_L	166_F	0.628	1.00
123_I	127_A	0.622	1.00
91_R	108_S	0.618	1.00
191_E	194_T	0.617	1.00
78_P	122_R	0.616	1.00
69_K	77_I	0.614	1.00
210_G	213_R	0.613	1.00
139_L	164_H	0.612	1.00
194_T	199_I	0.609	1.00
53_D	105_K	0.608	1.00
65_I	69_K	0.607	1.00
203_R	208_P	0.605	1.00
51_L	80_V	0.605	1.00
131_V	140_D	0.605	1.00
137_L	148_A	0.604	1.00
140_D	145_R	0.601	1.00
166_F	199_I	0.601	1.00
11_E	84_A	0.599	1.00
39_V	71_E	0.598	1.00
14_I	107_F	0.596	1.00
207_E	212_D	0.591	1.00
51_L	116_I	0.590	1.00
62_I	90_D	0.587	1.00
156_G	159_E	0.587	1.00
54_W	94_G	0.586	1.00
22_L	27_F	0.585	1.00
161_K	165_F	0.584	1.00
115_R	119_V	0.584	1.00
212_D	220_G	0.583	1.00
76_D	125_P	0.582	1.00
21_V	113_V	0.581	1.00
89_E	92_V	0.580	1.00
83_T	91_R	0.579	1.00
107_F	111_E	0.579	1.00
180_L	183_V	0.577	1.00
10_D	83_T	0.576	1.00
144_H	160_F	0.575	1.00
35_Y	56_L	0.574	1.00
42_L	64_F	0.572	1.00
114_A	117_K	0.572	1.00
168_T	174_Y	0.571	1.00
78_P	120_M	0.571	1.00
141_P	168_T	0.570	1.00
5_I	22_L	0.570	1.00
176_R	192_D	0.569	1.00
5_I	49_L	0.564	1.00
11_E	14_I	0.561	1.00
23_E	29_P	0.557	1.00
69_K	78_P	0.556	1.00
176_R	180_L	0.556	1.00
117_K	121_R	0.554	1.00
166_F	169_H	0.550	1.00
190_V	195_V	0.548	1.00
159_E	162_L	0.543	1.00
23_E	28_Q	0.542	1.00
148_A	207_E	0.538	1.00
92_V	95_L	0.535	1.00
131_V	134_M	0.532	1.00
200_R	203_R	0.530	1.00
52_L	56_L	0.523	1.00
68_L	77_I	0.521	1.00
213_R	216_Q	0.521	1.00
134_M	138_S	0.519	1.00
84_A	106_P	0.519	1.00
116_I	120_M	0.519	1.00
118_A	122_R	0.513	1.00
148_A	208_P	0.510	1.00
27_F	120_M	0.509	1.00
207_E	214_M	0.507	1.00
37_S	58_G	0.506	1.00
83_T	105_K	0.505	1.00
198_H	202_L	0.504	1.00
212_D	216_Q	0.503	1.00
10_D	56_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kgsA	1	0.9563	100	0.208	Contact Map
2gwrA	1	0.9694	100	0.211	Contact Map
1ys7A	2	0.9782	100	0.211	Contact Map
3r0jA	2	0.9607	100	0.214	Contact Map
2oqrA	2	0.9694	100	0.227	Contact Map
4b09A	2	0.9214	100	0.24	Contact Map
4kfcA	2	0.9694	100	0.242	Contact Map
1p2fA	1	0.9432	100	0.254	Contact Map
2hqrA	2	0.9476	100	0.255	Contact Map
3q9sA	1	0.9127	100	0.261	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0085 seconds.