OXC - ECOLI - GREMLIN Contacts

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OXC - Oxalyl-CoA decarboxylase

UniProt:	P0AFI0	Sequences: MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAFGFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14143
Length:	564 (528)
Sequences:	14348 (9234)
Seq/√Len:	401.9

ECOLI - OXC ILVB ILVI ILVG GCL POXB MEND
BACSU - ILVX ILVB MEND IOLD YDAP
HALSA - MEND
SULSO - Q7LXT8 Q97ZB3 Q97UP3 Q97U16 Q980V7 Q97V62 Q97XR3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
504_K	507_D	4.933	1.00
473_N	539_N	3.759	1.00
378_A	523_R	3.679	1.00
58_G	88_A	3.602	1.00
514_Y	528_T	3.430	1.00
236_E	256_H	3.330	1.00
230_Q	327_Q	3.244	1.00
24_D	70_K	3.070	1.00
518_T	521_E	3.020	1.00
202_T	332_E	2.933	1.00
515_N	541_V	2.926	1.00
230_Q	323_A	2.785	1.00
382_V	527_T	2.770	1.00
320_G	325_S	2.630	1.00
218_L	231_L	2.589	1.00
67_L	437_S	2.577	1.00
514_Y	536_T	2.516	1.00
512_V	534_K	2.505	1.00
19_K	45_G	2.487	1.00
255_T	409_Y	2.486	1.00
378_A	381_D	2.468	1.00
25_T	47_R	2.402	1.00
517_T	521_E	2.373	1.00
204_A	299_I	2.366	1.00
277_V	322_I	2.352	1.00
301_L	325_S	2.345	1.00
430_A	443_A	2.279	1.00
514_Y	525_A	2.257	1.00
271_A	274_V	2.255	1.00
76_T	85_G	2.241	1.00
501_R	504_K	2.165	1.00
515_N	539_N	2.135	1.00
71_P	155_V	2.120	1.00
381_D	523_R	2.114	1.00
512_V	528_T	2.105	1.00
451_G	509_F	2.099	1.00
83_L	87_T	2.054	1.00
276_L	279_A	2.052	1.00
51_F	57_A	2.048	1.00
12_H	40_H	2.032	1.00
505_L	508_A	2.018	1.00
100_I	151_I	2.013	1.00
89_L	101_M	2.010	1.00
207_L	316_V	1.959	1.00
103_S	163_Y	1.950	1.00
207_L	273_V	1.947	1.00
216_I	235_I	1.913	1.00
125_N	128_K	1.907	1.00
207_L	297_Q	1.899	1.00
503_D	513_G	1.871	1.00
516_V	525_A	1.859	1.00
146_A	164_L	1.846	1.00
434_S	466_P	1.837	1.00
16_E	20_Q	1.827	1.00
71_P	100_I	1.808	1.00
235_I	242_F	1.806	1.00
208_L	275_M	1.805	1.00
450_F	454_G	1.805	1.00
62_A	66_F	1.789	1.00
206_S	210_K	1.788	1.00
237_S	330_L	1.775	1.00
461_C	511_G	1.769	1.00
203_S	206_S	1.764	1.00
380_R	407_D	1.758	1.00
122_D	125_N	1.756	1.00
527_T	531_Q	1.753	1.00
198_P	328_G	1.737	1.00
8_T	16_E	1.722	1.00
384_R	388_D	1.718	1.00
233_E	237_S	1.711	1.00
523_R	527_T	1.708	1.00
237_S	334_K	1.704	1.00
521_E	524_H	1.697	1.00
389_I	433_A	1.689	1.00
471_I	537_I	1.686	1.00
216_I	275_M	1.685	1.00
529_G	538_I	1.684	1.00
197_C	200_S	1.682	1.00
347_I	351_H	1.679	1.00
512_V	536_T	1.671	1.00
393_N	445_E	1.661	1.00
232_R	236_E	1.644	1.00
216_I	240_I	1.626	1.00
425_I	429_Y	1.603	1.00
277_V	301_L	1.586	1.00
377_S	381_D	1.582	1.00
490_A	494_T	1.573	1.00
28_G	48_Y	1.568	1.00
517_T	541_V	1.566	1.00
393_N	449_A	1.564	1.00
507_D	512_V	1.560	1.00
344_W	348_L	1.548	1.00
270_N	347_I	1.544	1.00
38_A	48_Y	1.544	1.00
229_E	233_E	1.541	1.00
16_E	19_K	1.538	1.00
491_P	494_T	1.536	1.00
139_Q	142_D	1.532	1.00
379_V	444_I	1.518	1.00
131_A	163_Y	1.517	1.00
415_L	433_A	1.512	1.00
68_T	436_T	1.504	1.00
132_K	160_G	1.491	1.00
211_A	214_P	1.487	1.00
434_S	465_L	1.481	1.00
374_N	519_T	1.480	1.00
503_D	515_N	1.472	1.00
524_H	528_T	1.467	1.00
382_V	523_R	1.459	1.00
200_S	203_S	1.459	1.00
239_Q	258_L	1.458	1.00
308_I	319_V	1.455	1.00
135_F	164_L	1.454	1.00
460_I	511_G	1.451	1.00
17_A	148_A	1.450	1.00
208_L	273_V	1.444	1.00
242_F	252_L	1.440	1.00
14_I	166_L	1.423	1.00
524_H	527_T	1.420	1.00
413_R	439_S	1.420	1.00
102_I	166_L	1.418	1.00
56_S	456_E	1.418	1.00
470_V	538_I	1.414	1.00
374_N	378_A	1.413	1.00
140_P	173_A	1.405	1.00
460_I	467_V	1.401	1.00
342_L	346_D	1.400	1.00
85_G	101_M	1.398	1.00
205_I	332_E	1.388	1.00
457_I	511_G	1.386	1.00
51_F	60_A	1.384	1.00
378_A	382_V	1.381	1.00
346_D	350_I	1.375	1.00
470_V	526_L	1.371	1.00
384_R	440_P	1.365	1.00
71_P	151_I	1.360	1.00
352_K	356_A	1.358	1.00
14_I	147_L	1.354	1.00
375_A	540_V	1.347	1.00
205_I	329_M	1.347	1.00
454_G	505_L	1.345	1.00
349_N	352_K	1.340	1.00
388_D	440_P	1.340	1.00
273_V	299_I	1.336	1.00
233_E	330_L	1.329	1.00
234_F	238_A	1.323	1.00
100_I	154_S	1.323	1.00
47_R	463_Y	1.314	1.00
297_Q	315_A	1.314	1.00
442_V	530_I	1.312	1.00
89_L	99_M	1.311	1.00
434_S	440_P	1.307	1.00
423_M	452_F	1.306	1.00
201_V	332_E	1.301	1.00
435_V	465_L	1.301	1.00
21_N	151_I	1.301	1.00
431_I	460_I	1.301	1.00
82_F	103_S	1.300	1.00
470_V	540_V	1.295	1.00
25_T	435_V	1.288	1.00
491_P	495_D	1.288	1.00
383_L	442_V	1.283	1.00
468_T	529_G	1.277	1.00
211_A	273_V	1.275	1.00
21_N	148_A	1.274	1.00
215_L	271_A	1.266	1.00
505_L	509_F	1.262	1.00
503_D	507_D	1.260	1.00
108_R	169_N	1.255	1.00
196_P	325_S	1.253	1.00
277_V	326_M	1.248	1.00
350_I	354_Q	1.246	1.00
309_D	314_I	1.245	1.00
323_A	327_Q	1.245	1.00
58_G	85_G	1.244	1.00
466_P	534_K	1.243	1.00
385_E	409_Y	1.237	1.00
137_V	143_L	1.235	1.00
232_R	253_E	1.235	1.00
231_L	326_M	1.234	1.00
142_D	145_I	1.233	1.00
202_T	206_S	1.229	1.00
370_L	540_V	1.227	1.00
234_F	326_M	1.218	1.00
493_P	496_L	1.217	1.00
522_L	540_V	1.216	1.00
440_P	530_I	1.210	1.00
443_A	469_I	1.206	1.00
147_L	164_L	1.204	1.00
62_A	91_N	1.200	1.00
475_G	499_H	1.199	1.00
234_F	330_L	1.198	1.00
145_I	149_R	1.197	1.00
11_M	40_H	1.194	1.00
27_Y	64_S	1.191	1.00
65_G	98_P	1.187	1.00
466_P	533_R	1.186	1.00
389_I	437_S	1.186	1.00
49_I	435_V	1.185	1.00
9_D	12_H	1.176	1.00
64_S	436_T	1.174	1.00
504_K	508_A	1.164	1.00
511_G	537_I	1.163	1.00
198_P	332_E	1.162	1.00
26_I	41_A	1.160	1.00
458_E	462_R	1.156	1.00
232_R	252_L	1.155	1.00
24_D	47_R	1.154	1.00
506_M	511_G	1.149	1.00
370_L	375_A	1.148	1.00
324_S	327_Q	1.147	1.00
233_E	236_E	1.144	1.00
222_A	231_L	1.144	1.00
321_D	324_S	1.142	1.00
135_F	149_R	1.141	1.00
17_A	147_L	1.141	1.00
244_P	259_S	1.139	1.00
205_I	333_L	1.138	1.00
90_A	420_W	1.136	1.00
389_I	441_V	1.134	1.00
19_K	43_A	1.130	1.00
328_G	331_A	1.130	1.00
19_K	44_E	1.129	1.00
86_L	126_A	1.128	1.00
10_G	143_L	1.128	1.00
109_A	169_N	1.125	1.00
203_S	207_L	1.124	1.00
167_P	170_V	1.123	1.00
525_A	538_I	1.122	1.00
252_L	256_H	1.119	1.00
349_N	353_Q	1.118	1.00
86_L	130_Y	1.118	1.00
216_I	234_F	1.116	1.00
13_I	175_M	1.116	1.00
266_F	270_N	1.115	1.00
205_I	209_A	1.113	1.00
23_I	73_I	1.113	1.00
506_M	537_I	1.112	1.00
236_E	258_L	1.105	1.00
385_E	410_K	1.103	1.00
514_Y	538_I	1.103	1.00
485_L	488_A	1.102	1.00
230_Q	330_L	1.101	1.00
434_S	438_G	1.094	1.00
209_A	336_N	1.094	1.00
233_E	327_Q	1.090	1.00
62_A	97_F	1.083	1.00
214_P	272_D	1.080	1.00
135_F	146_A	1.080	1.00
67_L	433_A	1.078	1.00
434_S	441_V	1.076	1.00
522_L	526_L	1.073	1.00
108_R	173_A	1.070	1.00
153_V	162_V	1.070	1.00
213_R	270_N	1.068	1.00
74_C	85_G	1.067	1.00
506_M	513_G	1.067	1.00
230_Q	233_E	1.067	1.00
350_I	353_Q	1.063	1.00
512_V	532_S	1.060	1.00
93_T	161_G	1.059	1.00
137_V	146_A	1.051	1.00
490_A	495_D	1.044	1.00
9_D	174_T	1.044	1.00
204_A	316_V	1.043	1.00
218_L	222_A	1.042	1.00
276_L	281_L	1.041	1.00
126_A	130_Y	1.040	1.00
56_S	453_S	1.038	1.00
209_A	334_K	1.038	1.00
249_K	254_D	1.037	1.00
83_L	126_A	1.037	1.00
513_G	537_I	1.036	1.00
63_A	67_L	1.036	1.00
25_T	49_I	1.035	1.00
210_K	297_Q	1.035	1.00
204_A	318_V	1.028	1.00
383_L	390_Y	1.027	1.00
13_I	144_G	1.026	1.00
111_V	136_R	1.020	1.00
195_L	328_G	1.018	1.00
58_G	74_C	1.018	1.00
260_A	267_A	1.017	1.00
74_C	101_M	1.012	1.00
468_T	536_T	1.011	1.00
528_T	531_Q	1.010	1.00
235_I	252_L	1.007	1.00
14_I	102_I	1.006	1.00
229_E	232_R	1.005	1.00
49_I	463_Y	1.005	1.00
346_D	349_N	1.004	1.00
232_R	256_H	1.001	1.00
34_V	37_M	1.000	1.00
216_I	231_L	0.999	1.00
243_L	260_A	0.997	1.00
353_Q	357_Q	0.997	1.00
76_T	101_M	0.995	1.00
426_G	443_A	0.990	1.00
215_L	243_L	0.990	1.00
262_A	266_F	0.988	1.00
485_L	489_G	0.988	1.00
209_A	333_L	0.985	1.00
324_S	328_G	0.985	1.00
131_A	134_A	0.984	1.00
490_A	493_P	0.984	1.00
475_G	541_V	0.979	1.00
371_N	546_A	0.977	1.00
96_G	158_R	0.977	1.00
516_V	521_E	0.973	1.00
134_A	163_Y	0.971	1.00
234_F	333_L	0.969	1.00
516_V	522_L	0.967	1.00
26_I	73_I	0.964	1.00
391_L	443_A	0.964	1.00
314_I	317_P	0.963	1.00
471_I	502_Y	0.960	1.00
390_Y	406_I	0.959	1.00
427_M	450_F	0.959	1.00
532_S	536_T	0.959	1.00
211_A	272_D	0.958	1.00
491_P	496_L	0.954	1.00
37_M	166_L	0.954	1.00
348_L	352_K	0.954	1.00
440_P	468_T	0.953	1.00
391_L	441_V	0.952	1.00
450_F	471_I	0.951	1.00
286_A	289_K	0.951	1.00
457_I	537_I	0.949	1.00
301_L	318_V	0.945	1.00
8_T	174_T	0.945	1.00
386_N	439_S	0.942	1.00
105_S	165_D	0.942	1.00
155_V	159_P	0.938	1.00
529_G	536_T	0.938	1.00
380_R	406_I	0.937	1.00
468_T	530_I	0.934	1.00
235_I	258_L	0.934	1.00
82_F	127_A	0.931	1.00
503_D	539_N	0.927	1.00
199_K	202_T	0.927	1.00
58_G	99_M	0.927	1.00
133_A	153_V	0.924	1.00
228_D	232_R	0.924	1.00
318_V	325_S	0.921	1.00
14_I	37_M	0.921	1.00
206_S	209_A	0.919	1.00
457_I	469_I	0.919	1.00
454_G	509_F	0.918	1.00
210_K	273_V	0.918	1.00
124_M	134_A	0.917	1.00
196_P	328_G	0.917	1.00
230_Q	326_M	0.917	1.00
410_K	413_R	0.916	1.00
215_L	274_V	0.914	1.00
386_N	410_K	0.913	1.00
89_L	127_A	0.912	1.00
345_R	349_N	0.912	1.00
511_G	535_P	0.910	1.00
468_T	538_I	0.908	1.00
237_S	335_Q	0.907	1.00
376_L	444_I	0.907	1.00
525_A	529_G	0.906	1.00
70_K	155_V	0.905	1.00
204_A	207_L	0.902	1.00
233_E	334_K	0.900	1.00
472_F	542_I	0.899	1.00
133_A	146_A	0.899	1.00
10_G	140_P	0.896	1.00
458_E	509_F	0.896	1.00
434_S	534_K	0.895	1.00
60_A	460_I	0.891	1.00
12_H	16_E	0.889	1.00
195_L	324_S	0.887	1.00
293_A	296_T	0.882	1.00
375_A	472_F	0.879	1.00
382_V	526_L	0.879	1.00
8_T	13_I	0.879	1.00
492_S	496_L	0.878	1.00
460_I	469_I	0.874	1.00
66_F	97_F	0.872	1.00
374_N	522_L	0.871	1.00
464_N	533_R	0.871	1.00
83_L	90_A	0.866	1.00
521_E	525_A	0.866	1.00
41_A	46_I	0.866	1.00
215_L	268_L	0.862	1.00
204_A	273_V	0.860	1.00
450_F	537_I	0.859	1.00
492_S	495_D	0.858	1.00
124_M	136_R	0.858	1.00
198_P	202_T	0.857	1.00
149_R	153_V	0.854	1.00
125_N	129_P	0.853	1.00
254_D	259_S	0.852	1.00
17_A	21_N	0.851	1.00
67_L	415_L	0.850	1.00
86_L	127_A	0.849	1.00
432_G	436_T	0.848	1.00
133_A	150_A	0.847	1.00
507_D	513_G	0.844	1.00
73_I	100_I	0.842	1.00
348_L	351_H	0.839	1.00
467_V	535_P	0.839	1.00
154_S	162_V	0.838	1.00
401_N	444_I	0.837	1.00
343_V	346_D	0.834	1.00
448_S	477_I	0.831	1.00
87_T	422_V	0.831	1.00
100_I	155_V	0.830	1.00
238_A	333_L	0.828	1.00
460_I	535_P	0.828	1.00
206_S	336_N	0.827	1.00
63_A	429_Y	0.827	1.00
462_R	498_H	0.827	1.00
213_R	272_D	0.826	1.00
383_L	388_D	0.824	1.00
216_I	277_V	0.824	1.00
25_T	64_S	0.822	1.00
376_L	472_F	0.821	1.00
252_L	259_S	0.818	1.00
382_V	530_I	0.818	1.00
9_D	40_H	0.818	1.00
385_E	388_D	0.817	1.00
223_A	251_I	0.815	1.00
475_G	544_P	0.815	1.00
17_A	20_Q	0.814	1.00
227_A	230_Q	0.812	1.00
444_I	472_F	0.810	1.00
218_L	244_P	0.804	1.00
12_H	43_A	0.804	1.00
388_D	442_V	0.801	1.00
376_L	406_I	0.801	1.00
525_A	528_T	0.801	1.00
528_T	532_S	0.799	1.00
36_D	172_A	0.799	1.00
308_I	317_P	0.795	1.00
207_L	299_I	0.793	1.00
473_N	541_V	0.791	1.00
273_V	297_Q	0.789	1.00
378_A	522_L	0.789	1.00
442_V	470_V	0.787	1.00
140_P	144_G	0.786	1.00
166_L	171_L	0.785	1.00
30_V	50_G	0.785	1.00
490_A	496_L	0.783	1.00
397_N	449_A	0.778	1.00
209_A	331_A	0.778	1.00
12_H	42_Q	0.777	1.00
201_V	328_G	0.774	1.00
501_R	515_N	0.773	1.00
18_L	73_I	0.772	1.00
23_I	151_I	0.772	1.00
132_K	162_V	0.771	1.00
204_A	325_S	0.768	1.00
305_P	319_V	0.768	1.00
90_A	130_Y	0.768	1.00
214_P	240_I	0.765	1.00
468_T	533_R	0.765	1.00
461_C	535_P	0.764	1.00
431_I	465_L	0.763	1.00
21_N	155_V	0.763	1.00
347_I	350_I	0.760	1.00
77_V	119_E	0.760	1.00
218_L	242_F	0.757	1.00
520_D	524_H	0.757	1.00
51_F	56_S	0.755	1.00
133_A	149_R	0.752	1.00
75_L	102_I	0.752	1.00
59_Y	422_V	0.751	1.00
24_D	64_S	0.750	1.00
203_S	316_V	0.750	1.00
132_K	153_V	0.748	1.00
451_G	500_A	0.747	1.00
392_V	416_D	0.747	1.00
65_G	97_F	0.745	1.00
451_G	454_G	0.745	1.00
55_Q	84_N	0.744	1.00
380_R	409_Y	0.743	1.00
328_G	332_E	0.743	1.00
133_A	162_V	0.742	1.00
200_S	204_A	0.742	1.00
76_T	103_S	0.742	1.00
392_V	414_R	0.741	1.00
351_H	355_N	0.740	1.00
29_V	85_G	0.740	1.00
370_L	519_T	0.737	1.00
220_K	247_M	0.735	1.00
427_M	469_I	0.732	1.00
19_K	24_D	0.732	1.00
255_T	385_E	0.731	1.00
513_G	539_N	0.731	1.00
64_S	70_K	0.731	1.00
34_V	75_L	0.730	1.00
67_L	436_T	0.730	1.00
89_L	130_Y	0.728	1.00
65_G	99_M	0.727	1.00
152_R	156_S	0.726	1.00
136_R	165_D	0.726	1.00
501_R	507_D	0.724	1.00
209_A	332_E	0.724	1.00
275_M	301_L	0.721	1.00
226_Q	412_R	0.720	1.00
430_A	467_V	0.719	1.00
34_V	38_A	0.715	1.00
26_I	75_L	0.714	1.00
227_A	323_A	0.713	1.00
481_D	485_L	0.711	1.00
39_R	490_A	0.710	1.00
393_N	426_G	0.708	1.00
15_V	44_E	0.707	1.00
103_S	165_D	0.707	1.00
222_A	251_I	0.704	1.00
196_P	201_V	0.703	1.00
253_E	409_Y	0.703	1.00
27_Y	60_A	0.703	1.00
494_T	497_L	0.701	1.00
392_V	401_N	0.698	1.00
246_S	402_A	0.695	1.00
469_I	511_G	0.695	1.00
253_E	256_H	0.694	1.00
58_G	101_M	0.694	1.00
105_S	111_V	0.693	1.00
352_K	355_N	0.693	1.00
37_M	171_L	0.693	1.00
108_R	138_N	0.692	1.00
451_G	502_Y	0.691	1.00
140_P	175_M	0.690	1.00
207_L	210_K	0.688	1.00
444_I	470_V	0.687	1.00
343_V	347_I	0.686	1.00
470_V	522_L	0.685	1.00
327_Q	331_A	0.684	1.00
442_V	468_T	0.684	1.00
144_G	148_A	0.683	1.00
450_F	502_Y	0.682	0.99
300_Q	314_I	0.680	0.99
228_D	411_P	0.680	0.99
225_S	321_D	0.678	0.99
97_F	425_I	0.677	0.99
244_P	254_D	0.677	0.99
83_L	86_L	0.676	0.99
216_I	242_F	0.676	0.99
325_S	328_G	0.675	0.99
112_D	120_E	0.673	0.99
443_A	449_A	0.671	0.99
331_A	334_K	0.670	0.99
461_C	510_R	0.666	0.99
386_N	440_P	0.665	0.99
375_A	470_V	0.665	0.99
76_T	82_F	0.665	0.99
460_I	465_L	0.665	0.99
466_P	535_P	0.665	0.99
36_D	171_L	0.664	0.99
440_P	466_P	0.664	0.99
124_M	128_K	0.662	0.99
353_Q	356_A	0.662	0.99
200_S	318_V	0.659	0.99
327_Q	330_L	0.659	0.99
214_P	273_V	0.659	0.99
391_L	415_L	0.657	0.99
511_G	534_K	0.656	0.99
348_L	356_A	0.656	0.99
92_A	99_M	0.655	0.99
370_L	518_T	0.655	0.99
196_P	324_S	0.655	0.99
217_I	276_L	0.655	0.99
250_G	254_D	0.655	0.99
389_I	439_S	0.654	0.99
84_N	87_T	0.653	0.99
52_R	462_R	0.653	0.99
525_A	536_T	0.653	0.99
461_C	498_H	0.653	0.99
427_M	445_E	0.649	0.99
266_F	269_A	0.649	0.99
391_L	433_A	0.647	0.99
63_A	432_G	0.647	0.99
351_H	354_Q	0.646	0.99
64_S	68_T	0.646	0.99
221_G	302_D	0.645	0.99
427_M	456_E	0.644	0.99
230_Q	234_F	0.644	0.99
201_V	329_M	0.643	0.99
146_A	149_R	0.642	0.99
193_A	321_D	0.642	0.99
93_T	132_K	0.637	0.99
140_P	170_V	0.636	0.99
431_I	459_T	0.635	0.99
149_R	152_R	0.631	0.99
330_L	334_K	0.631	0.99
299_I	316_V	0.631	0.99
37_M	75_L	0.630	0.99
195_L	198_P	0.628	0.99
500_A	508_A	0.627	0.99
137_V	167_P	0.627	0.99
24_D	45_G	0.625	0.99
355_N	359_M	0.623	0.99
357_Q	360_H	0.623	0.99
153_V	157_G	0.623	0.99
516_V	538_I	0.621	0.99
217_I	245_M	0.621	0.99
8_T	12_H	0.620	0.99
212_E	272_D	0.618	0.99
34_V	104_G	0.617	0.99
237_S	333_L	0.616	0.99
127_A	163_Y	0.615	0.99
94_V	420_W	0.614	0.99
344_W	347_I	0.614	0.99
428_G	456_E	0.612	0.99
435_V	463_Y	0.612	0.99
430_A	441_V	0.612	0.99
501_R	539_N	0.611	0.99
132_K	157_G	0.610	0.99
59_Y	91_N	0.609	0.99
217_I	279_A	0.608	0.99
25_T	70_K	0.608	0.99
208_L	238_A	0.608	0.99
375_A	522_L	0.607	0.99
518_T	524_H	0.607	0.99
213_R	344_W	0.605	0.99
235_I	238_A	0.605	0.99
103_S	123_Q	0.603	0.99
26_I	46_I	0.603	0.99
10_G	13_I	0.603	0.99
322_I	327_Q	0.603	0.99
476_G	481_D	0.603	0.99
90_A	121_L	0.602	0.99
308_I	314_I	0.602	0.99
276_L	298_F	0.601	0.99
514_Y	532_S	0.600	0.99
533_R	536_T	0.599	0.99
477_I	480_G	0.599	0.99
468_T	534_K	0.599	0.99
108_R	167_P	0.597	0.99
265_S	269_A	0.597	0.99
415_L	425_I	0.594	0.99
445_E	469_I	0.593	0.99
239_Q	257_P	0.592	0.99
29_V	477_I	0.592	0.99
325_S	329_M	0.591	0.99
332_E	336_N	0.591	0.99
53_H	84_N	0.591	0.99
388_D	439_S	0.590	0.99
379_V	470_V	0.589	0.99
358_K	361_E	0.589	0.99
355_N	358_K	0.587	0.98
227_A	322_I	0.586	0.98
187_V	190_P	0.584	0.98
445_E	453_S	0.584	0.98
102_I	164_L	0.583	0.98
238_A	258_L	0.583	0.98
451_G	455_M	0.582	0.98
249_K	408_M	0.582	0.98
209_A	212_E	0.581	0.98
368_Q	518_T	0.581	0.98
19_K	46_I	0.578	0.98
433_A	441_V	0.578	0.98
100_I	164_L	0.578	0.98
500_A	505_L	0.577	0.98
480_G	484_D	0.576	0.98
372_Y	400_D	0.575	0.98
231_L	235_I	0.575	0.98
64_S	72_G	0.574	0.98
427_M	460_I	0.574	0.98
217_I	274_V	0.573	0.98
142_D	146_A	0.573	0.98
481_D	495_D	0.573	0.98
105_S	136_R	0.572	0.98
32_I	77_V	0.572	0.98
100_I	162_V	0.570	0.98
17_A	144_G	0.570	0.98
485_L	491_P	0.570	0.98
169_N	173_A	0.569	0.98
374_N	523_R	0.569	0.98
42_Q	45_G	0.568	0.98
201_V	318_V	0.568	0.98
368_Q	519_T	0.568	0.98
15_V	41_A	0.568	0.98
391_L	426_G	0.567	0.98
150_A	164_L	0.567	0.98
459_T	465_L	0.566	0.98
85_G	88_A	0.565	0.98
389_I	415_L	0.565	0.98
247_M	418_G	0.563	0.98
392_V	426_G	0.562	0.98
360_H	377_S	0.562	0.98
60_A	435_V	0.560	0.98
292_W	296_T	0.560	0.98
58_G	89_L	0.560	0.98
52_R	458_E	0.559	0.98
454_G	508_A	0.559	0.98
47_R	435_V	0.559	0.98
383_L	406_I	0.558	0.98
223_A	412_R	0.558	0.98
369_P	543_D	0.557	0.98
233_E	331_A	0.556	0.98
151_I	155_V	0.556	0.98
397_N	472_F	0.554	0.98
98_P	154_S	0.554	0.98
118_Y	421_G	0.553	0.98
135_F	162_V	0.553	0.98
458_E	500_A	0.553	0.98
31_G	77_V	0.552	0.98
71_P	154_S	0.552	0.98
108_R	170_V	0.551	0.98
373_F	546_A	0.550	0.98
85_G	103_S	0.549	0.98
102_I	147_L	0.549	0.98
212_E	343_V	0.549	0.98
108_R	139_Q	0.548	0.98
526_L	530_I	0.547	0.98
209_A	335_Q	0.547	0.98
516_V	524_H	0.547	0.98
232_R	235_I	0.547	0.98
287_H	290_K	0.546	0.98
24_D	68_T	0.545	0.98
257_P	261_A	0.545	0.98
461_C	464_N	0.543	0.98
123_Q	163_Y	0.541	0.97
239_Q	345_R	0.540	0.97
401_N	414_R	0.540	0.97
62_A	429_Y	0.539	0.97
450_F	469_I	0.539	0.97
13_I	177_K	0.538	0.97
116_G	120_E	0.536	0.97
132_K	156_S	0.536	0.97
20_Q	177_K	0.536	0.97
302_D	307_E	0.534	0.97
198_P	331_A	0.534	0.97
83_L	121_L	0.533	0.97
366_D	520_D	0.533	0.97
501_R	508_A	0.531	0.97
333_L	336_N	0.530	0.97
376_L	380_R	0.530	0.97
66_F	95_N	0.530	0.97
67_L	389_I	0.530	0.97
137_V	164_L	0.529	0.97
354_Q	357_Q	0.529	0.97
464_N	534_K	0.529	0.97
481_D	544_P	0.529	0.97
410_K	439_S	0.528	0.97
244_P	249_K	0.528	0.97
528_T	536_T	0.528	0.97
514_Y	524_H	0.526	0.97
250_G	413_R	0.525	0.97
65_G	71_P	0.525	0.97
456_E	459_T	0.525	0.97
500_A	509_F	0.524	0.97
332_E	335_Q	0.523	0.97
144_G	147_L	0.523	0.97
232_R	410_K	0.523	0.97
391_L	429_Y	0.522	0.97
307_E	310_S	0.522	0.97
427_M	454_G	0.521	0.97
344_W	349_N	0.521	0.97
196_P	320_G	0.521	0.97
512_V	533_R	0.521	0.97
468_T	532_S	0.520	0.97
29_V	51_F	0.520	0.97
473_N	502_Y	0.519	0.97
507_D	514_Y	0.519	0.97
17_A	151_I	0.518	0.97
49_I	459_T	0.517	0.97
383_L	530_I	0.517	0.97
223_A	228_D	0.517	0.97
469_I	537_I	0.517	0.97
73_I	151_I	0.517	0.97
141_Q	176_E	0.516	0.97
73_I	102_I	0.515	0.97
258_L	345_R	0.514	0.97
10_G	173_A	0.512	0.96
153_V	156_S	0.511	0.96
197_C	324_S	0.510	0.96
91_N	95_N	0.510	0.96
57_A	74_C	0.509	0.96
59_Y	88_A	0.509	0.96
254_D	407_D	0.508	0.96
396_A	479_R	0.507	0.96
93_T	131_A	0.507	0.96
65_G	72_G	0.506	0.96
27_Y	435_V	0.506	0.96
519_T	523_R	0.506	0.96
152_R	155_V	0.504	0.96
122_D	129_P	0.504	0.96
82_F	104_G	0.504	0.96
33_P	78_S	0.503	0.96
289_K	312_R	0.503	0.96
204_A	275_M	0.503	0.96
229_E	236_E	0.502	0.96
393_N	443_A	0.502	0.96
408_M	413_R	0.502	0.96
20_Q	183_T	0.500	0.96
244_P	251_I	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2q28A	4	0.9681	100	0.161	Contact Map
1ozhA	4	0.9504	100	0.164	Contact Map
1ybhA	4	0.977	100	0.166	Contact Map
2c31A	4	0.9574	100	0.17	Contact Map
1t9bA	2	0.9787	100	0.17	Contact Map
2x7jA	4	0.9805	100	0.171	Contact Map
2panA	3	0.9699	100	0.173	Contact Map
2uz1A	4	0.9592	100	0.178	Contact Map
2ihtA	4	0.9397	100	0.178	Contact Map
4rjjA	5	0.9645	100	0.18	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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