ODO2 - ECOLI - GREMLIN Contacts

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ODO2 - Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

UniProt:	P0AFG6	Sequences: MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAPAAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10980
Length:	405 (396)
Sequences:	7907 (4981)
Seq/√Len:	250.3

ECOLI - ODO2 ODP2
BACSU - ODB2 ODP2 ACOC ODO2
HALSA - Q9HN75

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
301_E	305_K	3.583	1.00
27_P	59_A	3.447	1.00
290_L	298_K	3.432	1.00
353_D	360_G	3.346	1.00
58_D	78_R	3.325	1.00
248_R	390_T	3.284	1.00
304_V	308_D	3.240	1.00
63_D	66_T	3.107	1.00
25_K	35_E	2.974	1.00
177_K	265_N	2.956	1.00
178_R	260_D	2.921	1.00
357_A	362_V	2.690	1.00
59_A	76_R	2.684	1.00
305_K	315_D	2.678	1.00
298_K	301_E	2.672	1.00
255_S	264_H	2.565	1.00
125_H	150_L	2.552	1.00
187_R	190_E	2.535	1.00
239_V	269_V	2.517	1.00
207_E	354_R	2.515	1.00
249_Y	390_T	2.514	1.00
128_D	131_A	2.491	1.00
25_K	57_L	2.447	1.00
242_V	321_F	2.407	1.00
32_V	54_D	2.395	1.00
357_A	364_I	2.393	1.00
24_H	36_V	2.367	1.00
5_D	76_R	2.313	1.00
353_D	366_P	2.248	1.00
22_T	64_E	2.230	1.00
208_V	370_L	2.186	1.00
179_V	263_Y	2.167	1.00
61_L	76_R	2.142	1.00
266_Y	286_D	2.125	1.00
5_D	73_I	2.124	1.00
290_L	294_D	2.067	1.00
62_E	72_Q	2.066	1.00
30_A	56_I	2.059	1.00
209_N	365_L	2.033	1.00
201_M	373_S	2.024	1.00
319_G	342_Q	1.957	1.00
358_V	363_E	1.951	1.00
358_V	361_Q	1.918	1.00
247_K	288_D	1.888	1.00
270_S	281_T	1.887	1.00
26_K	29_D	1.884	1.00
22_T	39_E	1.880	1.00
143_R	147_E	1.873	1.00
121_L	147_E	1.867	1.00
57_L	75_G	1.864	1.00
246_L	321_F	1.863	1.00
181_M	256_I	1.860	1.00
243_V	267_F	1.842	1.00
175_S	265_N	1.837	1.00
61_L	73_I	1.836	1.00
242_V	391_I	1.809	1.00
32_V	35_E	1.801	1.00
131_A	149_H	1.789	1.00
222_E	226_K	1.779	1.00
20_V	38_V	1.773	1.00
57_L	60_V	1.758	1.00
239_V	287_V	1.752	1.00
277_R	309_G	1.733	1.00
33_R	54_D	1.726	1.00
178_R	262_V	1.709	1.00
243_V	287_V	1.704	1.00
184_L	188_V	1.694	1.00
120_R	124_E	1.686	1.00
187_R	191_R	1.684	1.00
69_T	72_Q	1.673	1.00
390_T	393_E	1.663	1.00
268_D	285_R	1.658	1.00
239_V	271_M	1.654	1.00
122_L	129_A	1.632	1.00
238_Y	348_M	1.628	1.00
225_E	231_R	1.627	1.00
212_P	215_D	1.625	1.00
194_E	198_S	1.624	1.00
291_G	294_D	1.621	1.00
191_R	194_E	1.605	1.00
251_E	263_Y	1.601	1.00
239_V	299_I	1.600	1.00
254_A	263_Y	1.589	1.00
306_G	311_L	1.588	1.00
284_L	298_K	1.574	1.00
214_M	234_F	1.572	1.00
244_E	394_L	1.567	1.00
177_K	263_Y	1.559	1.00
38_V	74_L	1.559	1.00
271_M	299_I	1.555	1.00
4_V	53_A	1.549	1.00
24_H	39_E	1.547	1.00
286_D	289_T	1.525	1.00
114_L	129_A	1.518	1.00
196_K	201_M	1.491	1.00
355_P	362_V	1.483	1.00
219_Q	399_T	1.478	1.00
62_E	68_V	1.464	1.00
254_A	378_L	1.460	1.00
147_E	151_A	1.430	1.00
199_T	338_I	1.429	1.00
249_Y	386_G	1.406	1.00
251_E	383_E	1.392	1.00
121_L	146_V	1.389	1.00
239_V	323_I	1.385	1.00
336_P	347_G	1.382	1.00
343_S	378_L	1.371	1.00
185_R	188_V	1.369	1.00
389_V	393_E	1.365	1.00
134_G	141_L	1.364	1.00
211_K	365_L	1.356	1.00
39_E	48_E	1.351	1.00
245_A	391_I	1.349	1.00
205_F	333_M	1.338	1.00
299_I	303_A	1.330	1.00
321_F	344_A	1.329	1.00
193_L	197_N	1.327	1.00
257_D	260_D	1.322	1.00
353_D	364_I	1.310	1.00
6_I	75_G	1.300	1.00
127_L	132_I	1.292	1.00
176_E	262_V	1.286	1.00
27_P	63_D	1.282	1.00
176_E	265_N	1.281	1.00
261_V	378_L	1.266	1.00
221_G	231_R	1.265	1.00
354_R	367_M	1.265	1.00
204_T	384_S	1.258	1.00
242_V	387_F	1.248	1.00
121_L	125_H	1.245	1.00
56_I	78_R	1.236	1.00
370_L	391_I	1.230	1.00
190_E	194_E	1.229	1.00
180_P	260_D	1.228	1.00
346_L	391_I	1.214	1.00
178_R	257_D	1.212	1.00
144_E	148_K	1.211	1.00
266_Y	288_D	1.211	1.00
339_N	342_Q	1.210	1.00
7_L	73_I	1.205	1.00
26_K	60_V	1.204	1.00
355_P	364_I	1.203	1.00
218_K	222_E	1.200	1.00
215_D	219_Q	1.189	1.00
209_N	358_V	1.187	1.00
213_I	237_F	1.186	1.00
185_R	380_D	1.185	1.00
36_V	48_E	1.183	1.00
270_S	342_Q	1.181	1.00
240_K	244_E	1.172	1.00
21_A	46_V	1.157	1.00
204_T	374_Y	1.155	1.00
199_T	340_P	1.155	1.00
17_D	67_T	1.144	1.00
125_H	147_E	1.134	1.00
207_E	332_L	1.127	1.00
62_E	66_T	1.126	1.00
256_I	378_L	1.124	1.00
223_A	400_R	1.120	1.00
242_V	344_A	1.117	1.00
211_K	215_D	1.116	1.00
392_K	396_E	1.114	1.00
210_M	213_I	1.110	1.00
203_T	373_S	1.106	1.00
134_G	140_R	1.105	1.00
56_I	81_N	1.102	1.00
215_D	218_K	1.094	1.00
268_D	286_D	1.093	1.00
144_E	147_E	1.091	1.00
186_K	259_D	1.086	1.00
390_T	394_L	1.084	1.00
218_K	221_G	1.075	1.00
203_T	335_T	1.073	1.00
303_A	307_R	1.064	1.00
204_T	331_S	1.059	1.00
257_D	262_V	1.059	1.00
312_T	315_D	1.059	1.00
27_P	60_V	1.050	1.00
274_S	386_G	1.048	1.00
252_V	379_I	1.045	1.00
332_L	352_K	1.045	1.00
351_I	366_P	1.041	1.00
348_M	368_M	1.036	1.00
6_I	77_L	1.033	1.00
210_M	368_M	1.032	1.00
206_N	392_K	1.030	1.00
267_F	288_D	1.025	1.00
127_L	150_L	1.020	1.00
356_M	367_M	1.016	1.00
236_S	292_M	1.015	1.00
211_K	366_P	1.013	1.00
239_V	284_L	1.011	1.00
274_S	329_F	1.008	1.00
53_A	77_L	1.001	1.00
382_R	386_G	1.000	1.00
252_V	344_A	0.998	1.00
136_G	145_D	0.996	1.00
210_M	351_I	0.988	1.00
148_K	152_K	0.987	1.00
170_A	173_A	0.986	1.00
202_L	374_Y	0.986	1.00
244_E	247_K	0.985	1.00
193_L	199_T	0.985	1.00
129_A	141_L	0.984	1.00
8_V	18_A	0.980	1.00
280_V	311_L	0.979	1.00
20_V	74_L	0.977	1.00
27_P	58_D	0.974	1.00
346_L	372_L	0.973	1.00
239_V	295_I	0.969	1.00
122_L	127_L	0.965	1.00
176_E	266_Y	0.962	1.00
248_R	394_L	0.959	1.00
228_H	297_K	0.959	1.00
205_F	335_T	0.959	1.00
301_E	304_V	0.957	1.00
133_K	149_H	0.950	1.00
23_W	60_V	0.948	1.00
112_D	141_L	0.947	1.00
274_S	382_R	0.945	1.00
305_K	312_T	0.940	1.00
31_V	51_A	0.940	1.00
208_V	392_K	0.940	1.00
96_S	99_A	0.939	1.00
321_F	346_L	0.936	1.00
122_L	141_L	0.934	1.00
356_M	365_L	0.934	1.00
26_K	64_E	0.934	1.00
286_D	290_L	0.933	1.00
358_V	365_L	0.929	1.00
268_D	283_V	0.928	1.00
15_V	18_A	0.923	1.00
372_L	388_L	0.921	1.00
186_K	190_E	0.920	1.00
127_L	146_V	0.916	1.00
31_V	57_L	0.914	1.00
321_F	387_F	0.913	1.00
68_V	72_Q	0.912	1.00
214_M	366_P	0.911	1.00
188_V	192_L	0.910	1.00
176_E	264_H	0.910	1.00
114_L	122_L	0.909	1.00
11_L	18_A	0.909	1.00
6_I	37_L	0.908	1.00
220_Y	232_L	0.908	1.00
293_A	297_K	0.907	1.00
20_V	62_E	0.906	1.00
201_M	338_I	0.899	1.00
294_D	297_K	0.899	1.00
244_E	401_L	0.898	1.00
280_V	316_L	0.895	1.00
17_D	69_T	0.892	1.00
353_D	359_N	0.891	1.00
129_A	132_I	0.889	1.00
37_L	75_G	0.888	1.00
19_T	67_T	0.887	1.00
117_A	143_R	0.887	1.00
134_G	139_G	0.884	1.00
376_H	381_G	0.884	1.00
135_T	145_D	0.884	1.00
88_S	91_S	0.882	1.00
196_K	200_A	0.882	1.00
247_K	267_F	0.878	1.00
204_T	388_L	0.875	1.00
242_V	346_L	0.872	1.00
284_L	299_I	0.871	1.00
326_G	334_S	0.866	0.99
58_D	76_R	0.859	0.99
37_L	51_A	0.850	0.99
122_L	146_V	0.846	0.99
270_S	319_G	0.842	0.99
332_L	369_Y	0.840	0.99
122_L	132_I	0.840	0.99
148_K	151_A	0.838	0.99
24_H	48_E	0.835	0.99
360_G	364_I	0.834	0.99
118_I	146_V	0.832	0.99
34_D	50_P	0.827	0.99
284_L	290_L	0.826	0.99
321_F	372_L	0.825	0.99
374_Y	384_S	0.821	0.99
219_Q	397_D	0.820	0.99
135_T	139_G	0.815	0.99
132_I	149_H	0.810	0.99
114_L	118_I	0.810	0.99
40_I	49_V	0.803	0.99
153_A	156_K	0.800	0.99
253_N	320_N	0.800	0.99
183_R	186_K	0.798	0.99
216_L	237_F	0.798	0.99
136_G	139_G	0.798	0.99
60_V	66_T	0.796	0.99
332_L	350_A	0.793	0.99
135_T	142_T	0.792	0.99
60_V	63_D	0.792	0.99
208_V	395_L	0.791	0.99
311_L	316_L	0.790	0.99
118_I	143_R	0.788	0.99
175_S	266_Y	0.787	0.99
94_K	97_T	0.786	0.99
344_A	372_L	0.786	0.99
203_T	371_A	0.784	0.99
90_K	93_E	0.779	0.99
4_V	79_E	0.778	0.99
25_K	29_D	0.778	0.99
204_T	349_H	0.778	0.99
181_M	258_G	0.778	0.99
196_K	199_T	0.776	0.99
196_K	337_I	0.775	0.99
195_A	201_M	0.773	0.99
8_V	40_I	0.772	0.99
30_A	54_D	0.771	0.99
11_L	40_I	0.769	0.99
230_I	297_K	0.768	0.99
19_T	65_G	0.766	0.99
326_G	347_G	0.761	0.99
236_S	295_I	0.758	0.99
238_Y	368_M	0.755	0.99
118_I	122_L	0.752	0.99
134_G	145_D	0.752	0.99
16_A	69_T	0.750	0.99
169_P	173_A	0.747	0.98
207_E	352_K	0.747	0.98
192_L	281_T	0.745	0.98
249_Y	383_E	0.744	0.98
221_G	225_E	0.743	0.98
268_D	342_Q	0.743	0.98
171_L	174_R	0.742	0.98
252_V	383_E	0.741	0.98
285_R	314_E	0.740	0.98
268_D	319_G	0.736	0.98
181_M	261_V	0.734	0.98
184_L	275_T	0.733	0.98
348_M	370_L	0.731	0.98
238_Y	395_L	0.730	0.98
333_M	369_Y	0.727	0.98
210_M	395_L	0.725	0.98
121_L	127_L	0.723	0.98
273_V	307_R	0.723	0.98
244_E	248_R	0.723	0.98
184_L	277_R	0.722	0.98
206_N	331_S	0.722	0.98
246_L	267_F	0.722	0.98
169_P	174_R	0.721	0.98
205_F	371_A	0.716	0.98
154_P	157_E	0.716	0.98
196_K	203_T	0.713	0.98
344_A	379_I	0.713	0.98
242_V	245_A	0.713	0.98
21_A	65_G	0.713	0.98
232_L	237_F	0.711	0.98
294_D	298_K	0.710	0.98
33_R	51_A	0.708	0.98
146_V	149_H	0.706	0.98
191_R	339_N	0.706	0.98
223_A	227_R	0.706	0.98
179_V	251_E	0.706	0.98
10_D	13_E	0.705	0.98
122_L	128_D	0.704	0.98
275_T	280_V	0.704	0.98
305_K	310_K	0.703	0.98
196_K	373_S	0.700	0.98
313_V	317_T	0.698	0.98
234_F	351_I	0.697	0.98
222_E	225_E	0.697	0.98
121_L	143_R	0.696	0.98
314_E	317_T	0.696	0.98
232_L	236_S	0.694	0.98
322_T	342_Q	0.691	0.97
353_D	357_A	0.691	0.97
223_A	226_K	0.690	0.97
290_L	301_E	0.688	0.97
300_K	304_V	0.686	0.97
301_E	315_D	0.686	0.97
387_F	391_I	0.685	0.97
210_M	366_P	0.684	0.97
252_V	387_F	0.684	0.97
195_A	340_P	0.681	0.97
283_V	319_G	0.681	0.97
189_A	256_I	0.681	0.97
207_E	367_M	0.681	0.97
169_P	172_A	0.679	0.97
252_V	343_S	0.676	0.97
114_L	141_L	0.676	0.97
319_G	339_N	0.675	0.97
245_A	390_T	0.675	0.97
31_V	77_L	0.675	0.97
397_D	400_R	0.675	0.97
24_H	27_P	0.674	0.97
170_A	174_R	0.674	0.97
251_E	254_A	0.673	0.97
207_E	369_Y	0.673	0.97
56_I	80_G	0.672	0.97
163_A	166_A	0.668	0.97
246_L	252_V	0.665	0.97
225_E	228_H	0.664	0.97
193_L	196_K	0.664	0.97
212_P	399_T	0.663	0.97
220_Y	223_A	0.662	0.97
246_L	387_F	0.662	0.97
238_Y	323_I	0.659	0.97
30_A	80_G	0.659	0.97
370_L	388_L	0.658	0.97
4_V	7_L	0.658	0.97
204_T	326_G	0.657	0.97
112_D	130_S	0.656	0.97
305_K	311_L	0.656	0.97
283_V	318_G	0.656	0.97
5_D	61_L	0.655	0.97
118_I	141_L	0.655	0.97
372_L	384_S	0.655	0.97
150_L	153_A	0.654	0.97
93_E	96_S	0.654	0.97
51_A	54_D	0.651	0.96
51_A	77_L	0.648	0.96
398_P	401_L	0.647	0.96
89_A	93_E	0.647	0.96
27_P	76_R	0.646	0.96
151_A	154_P	0.646	0.96
157_E	160_P	0.646	0.96
112_D	129_A	0.643	0.96
235_M	328_V	0.640	0.96
93_E	97_T	0.639	0.96
58_D	80_G	0.639	0.96
95_A	99_A	0.637	0.96
319_G	340_P	0.634	0.96
326_G	331_S	0.634	0.96
147_E	150_L	0.633	0.96
116_P	119_R	0.633	0.96
11_L	49_V	0.632	0.96
8_V	68_V	0.632	0.96
226_K	229_G	0.631	0.96
268_D	315_D	0.631	0.96
213_I	395_L	0.630	0.96
18_A	45_V	0.626	0.96
20_V	60_V	0.625	0.95
18_A	40_I	0.624	0.95
89_A	92_E	0.624	0.95
36_V	39_E	0.624	0.95
360_G	366_P	0.623	0.95
11_L	14_S	0.622	0.95
125_H	151_A	0.621	0.95
235_M	238_Y	0.621	0.95
206_N	388_L	0.621	0.95
162_A	168_Q	0.618	0.95
214_M	351_I	0.616	0.95
212_P	365_L	0.615	0.95
34_D	54_D	0.613	0.95
393_E	400_R	0.612	0.95
203_T	347_G	0.611	0.95
80_G	83_A	0.607	0.95
193_L	200_A	0.606	0.95
338_I	344_A	0.605	0.95
386_G	389_V	0.604	0.95
87_T	91_S	0.603	0.95
282_P	319_G	0.603	0.95
312_T	317_T	0.603	0.95
181_M	257_D	0.602	0.94
383_E	386_G	0.602	0.94
146_V	150_L	0.600	0.94
235_M	271_M	0.600	0.94
285_R	315_D	0.600	0.94
165_P	168_Q	0.598	0.94
271_M	323_I	0.598	0.94
198_S	340_P	0.597	0.94
93_E	99_A	0.596	0.94
297_K	301_E	0.593	0.94
36_V	50_P	0.593	0.94
391_I	395_L	0.591	0.94
235_M	323_I	0.590	0.94
10_D	14_S	0.589	0.94
283_V	342_Q	0.589	0.94
109_Q	113_A	0.588	0.94
161_A	167_A	0.587	0.94
84_G	96_S	0.587	0.94
18_A	42_T	0.587	0.94
217_R	221_G	0.586	0.94
245_A	394_L	0.586	0.94
88_S	93_E	0.584	0.94
155_A	158_S	0.582	0.93
181_M	260_D	0.582	0.93
39_E	46_V	0.582	0.93
235_M	325_N	0.581	0.93
358_V	362_V	0.580	0.93
353_D	358_V	0.579	0.93
269_V	321_F	0.579	0.93
136_G	142_T	0.579	0.93
298_K	305_K	0.579	0.93
141_L	145_D	0.577	0.93
285_R	298_K	0.576	0.93
358_V	364_I	0.576	0.93
61_L	74_L	0.575	0.93
131_A	153_A	0.572	0.93
132_I	145_D	0.568	0.93
91_S	95_A	0.566	0.92
88_S	92_E	0.565	0.92
21_A	24_H	0.565	0.92
354_R	369_Y	0.564	0.92
243_V	247_K	0.563	0.92
241_A	395_L	0.563	0.92
211_K	356_M	0.563	0.92
149_H	153_A	0.563	0.92
132_I	146_V	0.562	0.92
97_T	100_Q	0.561	0.92
329_F	385_V	0.560	0.92
132_I	141_L	0.559	0.92
117_A	121_L	0.559	0.92
326_G	349_H	0.559	0.92
161_A	166_A	0.559	0.92
61_L	72_Q	0.556	0.92
353_D	362_V	0.556	0.92
255_S	262_V	0.555	0.92
349_H	385_V	0.554	0.92
139_G	145_D	0.553	0.92
25_K	75_G	0.552	0.92
92_E	96_S	0.552	0.92
272_A	279_L	0.551	0.91
352_K	356_M	0.551	0.91
97_T	101_R	0.551	0.91
6_I	52_S	0.550	0.91
140_R	145_D	0.549	0.91
38_V	49_V	0.549	0.91
162_A	165_P	0.549	0.91
274_S	383_E	0.547	0.91
23_W	62_E	0.547	0.91
334_S	349_H	0.546	0.91
79_E	82_S	0.546	0.91
115_S	142_T	0.545	0.91
209_N	356_M	0.545	0.91
185_R	189_A	0.545	0.91
333_M	371_A	0.543	0.91
23_W	38_V	0.542	0.91
131_A	154_P	0.542	0.91
104_A	107_E	0.542	0.91
333_M	336_P	0.541	0.91
8_V	75_G	0.541	0.91
7_L	71_R	0.540	0.91
78_R	81_N	0.540	0.91
20_V	52_S	0.539	0.91
161_A	164_A	0.539	0.91
175_S	286_D	0.538	0.90
289_T	294_D	0.537	0.90
227_R	230_I	0.536	0.90
205_F	369_Y	0.535	0.90
8_V	47_L	0.535	0.90
136_G	141_L	0.535	0.90
15_V	70_S	0.534	0.90
370_L	395_L	0.534	0.90
30_A	57_L	0.534	0.90
357_A	360_G	0.533	0.90
8_V	74_L	0.532	0.90
355_P	365_L	0.531	0.90
162_A	166_A	0.531	0.90
180_P	183_R	0.528	0.90
347_G	373_S	0.528	0.90
336_P	373_S	0.527	0.90
267_F	320_N	0.527	0.90
95_A	98_P	0.526	0.90
106_L	110_N	0.526	0.90
191_R	340_P	0.526	0.90
84_G	90_K	0.526	0.90
12_P	47_L	0.525	0.89
313_V	316_L	0.525	0.89
244_E	390_T	0.523	0.89
141_L	146_V	0.522	0.89
273_V	302_L	0.522	0.89
264_H	320_N	0.521	0.89
295_I	302_L	0.521	0.89
94_K	98_P	0.520	0.89
158_S	161_A	0.519	0.89
195_A	338_I	0.518	0.89
200_A	377_R	0.516	0.89
132_I	136_G	0.516	0.89
361_Q	364_I	0.515	0.89
4_V	78_R	0.513	0.88
346_L	370_L	0.513	0.88
221_G	230_I	0.513	0.88
191_R	341_P	0.511	0.88
281_T	342_Q	0.511	0.88
136_G	140_R	0.511	0.88
98_P	102_Q	0.509	0.88
61_L	75_G	0.507	0.88
181_M	378_L	0.506	0.88
87_T	90_K	0.506	0.88
195_A	199_T	0.505	0.88
159_A	162_A	0.505	0.88
106_L	109_Q	0.504	0.87
127_L	131_A	0.503	0.87
343_S	379_I	0.503	0.87
233_G	296_E	0.502	0.87
209_N	212_P	0.501	0.87
216_L	399_T	0.501	0.87
357_A	365_L	0.500	0.87
179_V	261_V	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dvaI	1	0.1037	100	0.141	Contact Map
1sczA	4	0.5753	100	0.45	Contact Map
2ii3A	4	0.5679	100	0.451	Contact Map
3maeA	3	0.5901	100	0.455	Contact Map
4n72A	3	0.6025	100	0.458	Contact Map
1dpbA	4	0.5951	100	0.458	Contact Map
3b8kA	1	0.5852	100	0.465	Contact Map
3l60A	3	0.5556	100	0.469	Contact Map
3rqcA	4	0.5383	100	0.482	Contact Map
2xt6A	2	0.4667	100	0.509	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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