NUOM - ECOLI - GREMLIN Contacts

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NUOM - NADH-quinone oxidoreductase subunit M

UniProt:	P0AFE8	Sequences: MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSLQLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAVLCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHKASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSGVEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSLPLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGSQLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFAVATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKSQIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTRP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11773
Length:	509 (455)
Sequences:	19974 (12435)
Seq/√Len:	583.0

ECOLI - NUOM HYFB NUOL HYCC HYFF HYFD NUON
BACSU - MRPA MRPD NDHF
HALSA - Q9HRL3 Q9HRL2 Q9HRT0 Q9HRS9 Q9HRL1 Q9HRS8
SULSO - Q980G8 Q97ZA6 Q97ZA9 Q980G9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
84_D	273_R	4.906	1.00
354_G	391_F	4.776	1.00
129_G	142_F	4.592	1.00
91_V	132_L	3.852	1.00
155_A	171_A	3.682	1.00
347_A	402_G	3.351	1.00
98_G	124_L	3.227	1.00
310_D	369_R	3.190	1.00
173_K	246_D	3.189	1.00
298_I	428_G	3.119	1.00
344_Q	406_G	2.989	1.00
309_T	372_R	2.856	1.00
13_G	35_T	2.788	1.00
389_L	440_L	2.763	1.00
294_G	331_Y	2.749	1.00
315_I	359_C	2.706	1.00
11_F	125_G	2.684	1.00
368_T	373_M	2.671	1.00
126_G	145_M	2.634	1.00
237_V	327_L	2.608	1.00
188_A	226_G	2.595	1.00
91_V	128_I	2.590	1.00
94_T	131_F	2.585	1.00
37_G	99_V	2.561	1.00
370_D	373_M	2.491	1.00
105_S	116_F	2.410	1.00
392_A	436_S	2.354	1.00
314_L	371_M	2.334	1.00
328_I	425_S	2.287	1.00
208_E	211_L	2.286	1.00
95_G	128_I	2.269	1.00
306_F	434_V	2.268	1.00
82_A	134_I	2.262	1.00
248_H	264_L	2.088	1.00
264_L	319_S	2.051	1.00
248_H	256_S	2.031	1.00
288_P	292_W	2.012	1.00
329_A	410_I	2.003	1.00
40_L	96_L	1.997	1.00
309_T	370_D	1.909	1.00
232_A	237_V	1.906	1.00
299_F	428_G	1.894	1.00
343_I	406_G	1.881	1.00
462_L	466_F	1.881	1.00
302_A	321_S	1.876	1.00
136_M	274_F	1.870	1.00
381_M	384_L	1.868	1.00
318_T	435_Y	1.852	1.00
438_A	442_R	1.824	1.00
291_M	331_Y	1.798	1.00
311_I	439_M	1.792	1.00
37_G	41_A	1.784	1.00
84_D	87_S	1.780	1.00
332_T	337_A	1.777	1.00
43_S	95_G	1.774	1.00
340_G	413_G	1.755	1.00
481_Y	484_P	1.741	1.00
191_A	223_L	1.727	1.00
209_E	213_T	1.725	1.00
87_S	269_Y	1.710	1.00
236_P	244_L	1.704	1.00
209_E	212_N	1.692	1.00
93_L	349_G	1.688	1.00
170_A	250_Q	1.662	1.00
308_Q	313_R	1.643	1.00
139_F	270_G	1.640	1.00
228_F	232_A	1.637	1.00
411_L	425_S	1.637	1.00
238_V	296_I	1.633	1.00
133_A	138_L	1.621	1.00
285_E	288_P	1.621	1.00
378_W	385_P	1.619	1.00
119_N	152_F	1.616	1.00
350_L	474_L	1.614	1.00
89_L	346_I	1.609	1.00
414_S	422_T	1.573	1.00
295_V	424_I	1.570	1.00
272_L	330_I	1.563	1.00
473_V	477_L	1.555	1.00
82_A	85_G	1.549	1.00
290_A	331_Y	1.546	1.00
384_L	459_G	1.540	1.00
218_G	222_L	1.526	1.00
412_F	416_Q	1.517	1.00
47_W	51_G	1.499	1.00
388_S	392_A	1.472	1.00
231_F	270_G	1.470	1.00
44_L	48_L	1.459	1.00
390_F	472_V	1.451	1.00
102_V	120_L	1.438	1.00
302_A	428_G	1.437	1.00
271_L	327_L	1.434	1.00
135_D	203_W	1.432	1.00
228_F	290_A	1.426	1.00
27_V	30_W	1.426	1.00
102_V	117_H	1.419	1.00
388_S	439_M	1.417	1.00
7_I	125_G	1.414	1.00
188_A	230_A	1.412	1.00
330_I	341_A	1.412	1.00
107_K	110_E	1.407	1.00
237_V	293_L	1.405	1.00
291_M	421_I	1.398	1.00
210_L	213_T	1.398	1.00
41_A	45_Q	1.392	1.00
89_L	342_V	1.379	1.00
351_S	394_A	1.377	1.00
287_A	291_M	1.374	1.00
35_T	39_T	1.371	1.00
130_V	266_T	1.367	1.00
188_A	227_F	1.366	1.00
39_T	43_S	1.361	1.00
153_L	255_G	1.353	1.00
355_L	391_F	1.352	1.00
135_D	204_T	1.347	1.00
326_V	341_A	1.343	1.00
83_I	132_L	1.336	1.00
385_P	445_F	1.336	1.00
204_T	209_E	1.334	1.00
36_M	40_L	1.328	1.00
470_L	474_L	1.328	1.00
104_C	357_I	1.327	1.00
272_L	341_A	1.319	1.00
462_L	465_L	1.316	1.00
332_T	414_S	1.307	1.00
193_V	203_W	1.306	1.00
337_A	413_G	1.306	1.00
469_L	473_V	1.305	1.00
48_L	52_Y	1.305	1.00
139_F	205_F	1.303	1.00
385_P	440_L	1.300	1.00
246_D	313_R	1.290	1.00
483_Q	487_D	1.287	1.00
329_A	341_A	1.280	1.00
329_A	337_A	1.280	1.00
177_Y	242_G	1.271	1.00
188_A	223_L	1.269	1.00
26_K	30_W	1.262	1.00
166_T	250_Q	1.261	1.00
14_G	17_C	1.260	1.00
97_L	353_A	1.255	1.00
328_I	414_S	1.253	1.00
185_M	230_A	1.252	1.00
26_K	29_R	1.250	1.00
18_W	21_E	1.248	1.00
14_G	122_W	1.243	1.00
80_H	134_I	1.239	1.00
461_S	464_E	1.232	1.00
25_V	29_R	1.228	1.00
7_I	10_P	1.222	1.00
123_I	127_V	1.220	1.00
300_Y	304_M	1.214	1.00
467_M	470_L	1.214	1.00
387_L	472_V	1.210	1.00
32_A	117_H	1.210	1.00
100_L	470_L	1.209	1.00
199_A	223_L	1.194	1.00
393_V	398_M	1.193	1.00
358_L	388_S	1.193	1.00
136_M	189_I	1.192	1.00
392_A	440_L	1.189	1.00
391_F	472_V	1.188	1.00
90_M	345_M	1.186	1.00
45_Q	48_L	1.182	1.00
340_G	409_M	1.182	1.00
191_A	219_V	1.182	1.00
97_L	349_G	1.181	1.00
36_M	39_T	1.178	1.00
484_P	487_D	1.170	1.00
292_W	296_I	1.168	1.00
365_R	381_M	1.167	1.00
347_A	406_G	1.166	1.00
208_E	212_N	1.160	1.00
321_S	432_A	1.159	1.00
383_W	386_A	1.158	1.00
232_A	293_L	1.152	1.00
238_V	300_Y	1.152	1.00
395_T	436_S	1.148	1.00
189_I	227_F	1.146	1.00
169_T	173_K	1.140	1.00
6_L	10_P	1.136	1.00
36_M	102_V	1.133	1.00
14_G	18_W	1.131	1.00
371_M	443_A	1.127	1.00
95_G	99_V	1.125	1.00
474_L	478_L	1.119	1.00
389_L	444_Y	1.117	1.00
23_F	26_K	1.116	1.00
363_Y	369_R	1.115	1.00
463_R	467_M	1.115	1.00
294_G	324_G	1.104	1.00
40_L	95_G	1.104	1.00
17_C	21_E	1.100	1.00
14_G	118_L	1.100	1.00
137_F	203_W	1.097	1.00
140_F	186_L	1.094	1.00
388_S	444_Y	1.083	1.00
45_Q	49_Q	1.083	1.00
107_K	463_R	1.080	1.00
223_L	227_F	1.078	1.00
216_S	220_E	1.075	1.00
40_L	44_L	1.075	1.00
384_L	460_M	1.068	1.00
83_I	88_L	1.065	1.00
68_D	78_S	1.062	1.00
34_I	38_L	1.062	1.00
420_V	423_V	1.062	1.00
167_R	250_Q	1.061	1.00
6_L	42_L	1.061	1.00
181_S	233_V	1.055	1.00
358_L	468_I	1.052	1.00
86_L	272_L	1.052	1.00
150_M	263_L	1.051	1.00
409_M	412_F	1.049	1.00
30_W	34_I	1.047	1.00
415_F	422_T	1.040	1.00
233_V	240_L	1.039	1.00
387_L	469_L	1.039	1.00
99_V	103_L	1.035	1.00
87_S	273_R	1.032	1.00
432_A	435_Y	1.031	1.00
383_W	469_L	1.029	1.00
301_G	324_G	1.027	1.00
185_M	189_I	1.023	1.00
387_L	468_I	1.020	1.00
268_A	326_V	1.016	1.00
13_G	17_C	1.016	1.00
202_V	205_F	1.012	1.00
423_V	427_F	1.008	1.00
97_L	261_G	1.007	1.00
9_I	13_G	1.004	1.00
383_W	387_L	1.003	1.00
217_S	221_Y	1.001	1.00
122_W	149_P	0.998	1.00
94_T	124_L	0.998	1.00
121_M	125_G	0.996	1.00
288_P	291_M	0.994	1.00
46_L	49_Q	0.985	1.00
192_L	223_L	0.983	1.00
96_L	100_L	0.981	1.00
257_V	357_I	0.981	1.00
366_I	374_M	0.981	1.00
284_A	287_A	0.979	1.00
120_L	258_D	0.975	1.00
402_G	478_L	0.972	1.00
385_P	444_Y	0.971	1.00
39_T	46_L	0.969	1.00
199_A	219_V	0.969	1.00
361_Q	384_L	0.969	1.00
225_L	229_I	0.968	1.00
136_M	210_L	0.967	1.00
159_H	167_R	0.967	1.00
86_L	342_V	0.962	1.00
134_I	204_T	0.962	1.00
228_F	271_L	0.960	1.00
32_A	36_M	0.956	1.00
268_A	327_L	0.955	1.00
245_P	317_Y	0.954	1.00
31_I	35_T	0.953	1.00
348_H	352_A	0.952	1.00
221_Y	286_F	0.952	1.00
43_S	46_L	0.951	1.00
77_I	137_F	0.949	1.00
70_P	73_P	0.948	1.00
354_G	471_L	0.948	1.00
371_M	442_R	0.948	1.00
235_M	268_A	0.945	1.00
32_A	35_T	0.943	1.00
28_P	32_A	0.942	1.00
265_K	269_Y	0.938	1.00
216_S	219_V	0.937	1.00
428_G	431_F	0.933	1.00
311_I	359_C	0.930	1.00
362_L	377_L	0.929	1.00
93_L	346_I	0.929	1.00
104_C	360_G	0.928	1.00
215_M	218_G	0.926	1.00
302_A	431_F	0.926	1.00
271_L	330_I	0.925	1.00
38_L	42_L	0.924	1.00
310_D	370_D	0.921	1.00
277_P	280_P	0.921	1.00
46_L	50_G	0.921	1.00
128_I	132_L	0.920	1.00
28_P	31_I	0.919	1.00
364_E	458_P	0.917	1.00
477_L	481_Y	0.917	1.00
107_K	461_S	0.917	1.00
375_G	442_R	0.915	1.00
42_L	46_L	0.911	1.00
221_Y	285_E	0.910	1.00
48_L	51_G	0.910	1.00
253_T	312_K	0.910	1.00
218_G	221_Y	0.909	1.00
294_G	328_I	0.907	1.00
466_F	470_L	0.905	1.00
302_A	435_Y	0.905	1.00
101_A	357_I	0.905	1.00
375_G	449_K	0.904	1.00
322_H	344_Q	0.901	1.00
25_V	28_P	0.898	1.00
168_I	171_A	0.896	1.00
295_V	328_I	0.896	1.00
184_V	226_G	0.895	1.00
87_S	91_V	0.892	1.00
184_V	229_I	0.892	1.00
151_Y	171_A	0.891	1.00
140_F	189_I	0.890	1.00
380_K	448_A	0.890	1.00
222_L	226_G	0.890	1.00
326_V	345_M	0.889	1.00
244_L	248_H	0.889	1.00
296_I	300_Y	0.886	1.00
329_A	340_G	0.885	1.00
260_A	352_A	0.884	1.00
361_Q	468_I	0.883	1.00
472_V	476_V	0.882	1.00
126_G	142_F	0.880	1.00
343_I	347_A	0.878	1.00
291_M	294_G	0.878	1.00
248_H	319_S	0.877	1.00
50_G	88_L	0.876	1.00
295_V	421_I	0.876	1.00
402_G	475_L	0.872	1.00
92_V	96_L	0.871	1.00
140_F	144_E	0.870	1.00
126_G	149_P	0.868	1.00
298_I	324_G	0.867	1.00
154_I	247_A	0.865	1.00
269_Y	273_R	0.864	1.00
165_K	169_T	0.863	1.00
217_S	220_E	0.862	1.00
361_Q	460_M	0.861	1.00
214_P	217_S	0.861	1.00
22_R	25_V	0.860	1.00
298_I	328_I	0.859	1.00
365_R	464_E	0.855	1.00
29_R	33_L	0.854	1.00
411_L	422_T	0.850	1.00
294_G	327_L	0.848	1.00
322_H	432_A	0.847	1.00
311_I	374_M	0.845	1.00
325_F	410_I	0.844	1.00
408_F	412_F	0.843	1.00
436_S	439_M	0.839	1.00
221_Y	225_L	0.839	1.00
335_Q	339_Q	0.834	1.00
319_S	348_H	0.832	1.00
357_I	467_M	0.830	1.00
334_S	337_A	0.830	1.00
314_L	439_M	0.826	1.00
43_S	91_V	0.825	1.00
81_L	132_L	0.823	1.00
123_I	150_M	0.823	1.00
80_H	135_D	0.822	1.00
379_S	382_K	0.821	1.00
392_A	439_M	0.820	1.00
268_A	345_M	0.817	1.00
334_S	413_G	0.812	1.00
18_W	118_L	0.812	1.00
305_A	435_Y	0.808	1.00
98_G	120_L	0.805	1.00
301_G	304_M	0.801	1.00
100_L	467_M	0.799	1.00
322_H	435_Y	0.797	1.00
449_K	452_I	0.796	1.00
186_L	190_L	0.794	1.00
90_M	269_Y	0.792	1.00
303_W	431_F	0.791	1.00
7_I	81_L	0.786	1.00
127_V	263_L	0.786	1.00
179_Q	182_G	0.785	1.00
127_V	146_M	0.784	1.00
315_I	355_L	0.784	1.00
66_E	80_H	0.784	1.00
465_L	469_L	0.783	1.00
351_S	403_N	0.783	1.00
44_L	92_V	0.781	1.00
397_G	407_E	0.780	1.00
143_W	185_M	0.780	1.00
39_T	42_L	0.777	1.00
146_M	263_L	0.775	1.00
291_M	328_I	0.771	1.00
274_F	278_L	0.770	1.00
301_G	321_S	0.769	1.00
291_M	295_V	0.768	1.00
262_I	265_K	0.765	1.00
166_T	169_T	0.765	1.00
386_A	444_Y	0.765	1.00
472_V	475_L	0.761	1.00
375_G	446_G	0.759	1.00
224_M	286_F	0.755	1.00
33_L	36_M	0.754	1.00
261_G	265_K	0.754	1.00
385_P	389_L	0.754	1.00
440_L	445_F	0.752	1.00
116_F	254_A	0.746	1.00
94_T	127_V	0.742	1.00
10_P	13_G	0.741	1.00
43_S	50_G	0.741	1.00
424_I	428_G	0.740	1.00
83_I	87_S	0.740	1.00
295_V	299_F	0.738	1.00
131_F	269_Y	0.738	1.00
390_F	476_V	0.736	1.00
251_A	260_A	0.734	1.00
108_E	254_A	0.732	1.00
394_A	401_T	0.732	1.00
7_I	132_L	0.731	1.00
47_W	92_V	0.731	1.00
308_Q	317_Y	0.729	1.00
192_L	227_F	0.728	1.00
33_L	37_G	0.727	1.00
30_W	33_L	0.727	1.00
151_Y	178_T	0.726	1.00
181_S	230_A	0.723	1.00
106_W	463_R	0.723	1.00
396_L	433_S	0.722	1.00
14_G	125_G	0.722	1.00
289_I	292_W	0.721	1.00
29_R	32_A	0.719	1.00
332_T	417_V	0.719	1.00
460_M	465_L	0.719	1.00
344_Q	351_S	0.716	1.00
88_L	92_V	0.716	1.00
146_M	266_T	0.715	1.00
127_V	262_I	0.715	1.00
268_A	323_M	0.714	1.00
466_F	469_L	0.713	1.00
459_G	465_L	0.710	1.00
386_A	390_F	0.708	1.00
101_A	257_V	0.702	1.00
383_W	465_L	0.701	1.00
134_I	138_L	0.700	1.00
135_D	138_L	0.696	1.00
39_T	128_I	0.694	1.00
272_L	338_Y	0.694	1.00
401_T	405_V	0.692	1.00
154_I	251_A	0.692	1.00
116_F	255_G	0.692	1.00
351_S	475_L	0.692	1.00
36_M	46_L	0.691	1.00
325_F	428_G	0.691	1.00
136_M	192_L	0.690	1.00
302_A	318_T	0.688	1.00
204_T	208_E	0.688	1.00
437_L	441_H	0.687	1.00
264_L	269_Y	0.687	1.00
318_T	348_H	0.685	1.00
9_I	35_T	0.684	1.00
368_T	374_M	0.684	1.00
68_D	71_W	0.683	1.00
80_H	204_T	0.683	1.00
123_I	258_D	0.682	1.00
477_L	484_P	0.680	1.00
433_S	437_L	0.678	1.00
193_V	200_T	0.678	1.00
299_F	303_W	0.677	1.00
43_S	92_V	0.674	1.00
8_L	12_I	0.673	1.00
22_R	26_K	0.672	1.00
27_V	31_I	0.671	1.00
294_G	298_I	0.671	1.00
143_W	266_T	0.668	1.00
39_T	95_G	0.668	1.00
251_A	256_S	0.668	1.00
387_L	465_L	0.668	1.00
400_G	480_F	0.666	1.00
13_G	39_T	0.666	1.00
123_I	263_L	0.665	1.00
13_G	31_I	0.661	1.00
13_G	121_M	0.660	1.00
32_A	102_V	0.660	1.00
172_T	176_I	0.658	1.00
256_S	259_L	0.658	1.00
67_F	70_P	0.657	1.00
191_A	199_A	0.653	1.00
154_I	259_L	0.653	1.00
387_L	391_F	0.653	1.00
31_I	34_I	0.653	1.00
256_S	264_L	0.652	1.00
450_S	453_A	0.651	1.00
304_M	317_Y	0.649	1.00
377_L	381_M	0.649	1.00
389_L	445_F	0.647	1.00
139_F	185_M	0.645	1.00
311_I	443_A	0.643	1.00
219_V	223_L	0.642	1.00
440_L	444_Y	0.642	1.00
220_E	223_L	0.641	1.00
224_M	228_F	0.641	1.00
115_F	119_N	0.640	1.00
253_T	360_G	0.639	1.00
411_L	426_T	0.639	1.00
40_L	47_W	0.639	1.00
13_G	18_W	0.639	1.00
66_E	69_M	0.639	1.00
100_L	471_L	0.639	1.00
478_L	485_I	0.639	1.00
96_L	474_L	0.638	1.00
337_A	341_A	0.637	1.00
191_A	222_L	0.635	1.00
322_H	352_A	0.635	1.00
319_S	323_M	0.634	1.00
378_W	389_L	0.634	1.00
261_G	353_A	0.631	1.00
358_L	387_L	0.630	1.00
405_V	409_M	0.628	1.00
381_M	459_G	0.627	1.00
97_L	258_D	0.626	1.00
86_L	90_M	0.625	1.00
9_I	38_L	0.622	1.00
43_S	47_W	0.622	1.00
336_L	416_Q	0.622	1.00
248_H	261_G	0.621	1.00
260_A	348_H	0.619	1.00
222_L	225_L	0.618	1.00
378_W	444_Y	0.617	1.00
281_N	285_E	0.615	1.00
244_L	247_A	0.614	1.00
364_E	464_E	0.614	1.00
298_I	325_F	0.613	1.00
385_P	443_A	0.613	1.00
430_V	434_V	0.612	1.00
116_F	156_L	0.610	1.00
68_D	73_P	0.609	1.00
228_F	293_L	0.606	1.00
220_E	282_A	0.605	1.00
94_T	128_I	0.604	1.00
253_T	256_S	0.603	1.00
95_G	124_L	0.601	1.00
386_A	389_L	0.600	1.00
70_P	78_S	0.598	1.00
256_S	312_K	0.598	1.00
434_V	438_A	0.597	1.00
346_I	485_I	0.597	1.00
35_T	121_M	0.597	1.00
10_P	39_T	0.596	1.00
462_L	467_M	0.596	1.00
285_E	289_I	0.596	1.00
344_Q	347_A	0.595	1.00
202_V	210_L	0.594	1.00
302_A	432_A	0.593	1.00
318_T	322_H	0.593	1.00
245_P	320_V	0.588	1.00
105_S	109_I	0.588	1.00
354_G	468_I	0.586	1.00
103_L	467_M	0.586	1.00
304_M	307_A	0.584	1.00
411_L	429_L	0.584	1.00
299_F	424_I	0.584	1.00
25_V	32_A	0.582	1.00
202_V	209_E	0.582	1.00
12_I	16_L	0.581	1.00
25_V	30_W	0.580	1.00
242_G	245_P	0.580	1.00
343_I	409_M	0.580	1.00
350_L	402_G	0.580	1.00
252_P	312_K	0.579	1.00
397_G	401_T	0.578	1.00
371_M	439_M	0.578	1.00
39_T	45_Q	0.576	1.00
413_G	417_V	0.576	1.00
397_G	403_N	0.575	1.00
92_V	95_G	0.575	1.00
90_M	94_T	0.575	1.00
351_S	395_T	0.574	1.00
361_Q	464_E	0.574	1.00
248_H	316_A	0.574	1.00
65_S	68_D	0.574	1.00
73_P	76_G	0.573	1.00
6_L	39_T	0.572	1.00
409_M	486_L	0.572	1.00
304_M	308_Q	0.572	1.00
476_V	480_F	0.571	1.00
201_G	204_T	0.571	1.00
71_W	76_G	0.571	1.00
308_Q	314_L	0.570	1.00
376_G	448_A	0.570	1.00
382_K	386_A	0.569	1.00
40_L	52_Y	0.569	1.00
235_M	271_L	0.566	1.00
428_G	432_A	0.566	1.00
476_V	479_G	0.565	1.00
394_A	403_N	0.565	1.00
134_I	208_E	0.564	0.99
33_L	103_L	0.563	0.99
238_V	301_G	0.562	0.99
244_L	264_L	0.562	0.99
292_W	295_V	0.561	0.99
358_L	391_F	0.560	0.99
70_P	76_G	0.559	0.99
100_L	353_A	0.559	0.99
20_T	23_F	0.555	0.99
361_Q	365_R	0.553	0.99
10_P	14_G	0.553	0.99
190_L	198_N	0.553	0.99
98_G	258_D	0.553	0.99
483_Q	486_L	0.552	0.99
219_V	222_L	0.549	0.99
136_M	205_F	0.548	0.99
303_W	307_A	0.547	0.99
200_T	204_T	0.546	0.99
105_S	254_A	0.544	0.99
101_A	254_A	0.544	0.99
112_Y	157_W	0.543	0.99
322_H	325_F	0.543	0.99
318_T	352_A	0.543	0.99
396_L	437_L	0.542	0.99
311_I	362_L	0.539	0.99
19_Q	22_R	0.538	0.99
86_L	269_Y	0.538	0.99
101_A	120_L	0.538	0.99
309_T	318_T	0.536	0.99
224_M	279_F	0.536	0.99
413_G	416_Q	0.535	0.99
63_W	66_E	0.534	0.99
256_S	348_H	0.534	0.99
192_L	278_L	0.534	0.99
350_L	471_L	0.532	0.99
169_T	246_D	0.532	0.99
358_L	384_L	0.531	0.99
426_T	429_L	0.530	0.99
420_V	424_I	0.530	0.99
228_F	286_F	0.530	0.99
405_V	479_G	0.530	0.99
133_A	142_F	0.530	0.99
144_E	234_K	0.528	0.99
380_K	457_L	0.527	0.99
273_R	277_P	0.526	0.99
94_T	98_G	0.526	0.99
119_N	149_P	0.526	0.99
405_V	480_F	0.526	0.99
134_I	273_R	0.526	0.99
265_K	268_A	0.524	0.99
124_L	128_I	0.523	0.99
29_R	40_L	0.522	0.99
66_E	70_P	0.520	0.99
32_A	39_T	0.520	0.99
427_F	431_F	0.519	0.99
371_M	374_M	0.519	0.99
399_P	404_F	0.519	0.99
150_M	154_I	0.518	0.99
251_A	258_D	0.518	0.99
390_F	394_A	0.518	0.99
40_L	99_V	0.518	0.99
407_E	429_L	0.517	0.99
325_F	425_S	0.516	0.99
264_L	268_A	0.516	0.99
177_Y	233_V	0.515	0.99
339_Q	486_L	0.514	0.99
337_A	340_G	0.514	0.99
103_L	466_F	0.513	0.99
6_L	18_W	0.513	0.99
363_Y	367_H	0.513	0.99
266_T	270_G	0.511	0.99
382_K	385_P	0.511	0.99
7_I	14_G	0.511	0.99
265_K	323_M	0.510	0.99
441_H	446_G	0.510	0.99
140_F	182_G	0.509	0.99
170_A	246_D	0.509	0.99
199_A	203_W	0.508	0.99
83_I	91_V	0.508	0.99
416_Q	419_P	0.507	0.99
159_H	165_K	0.507	0.99
393_V	437_L	0.507	0.99
15_F	18_W	0.507	0.99
33_L	99_V	0.505	0.99
21_E	25_V	0.505	0.99
379_S	448_A	0.505	0.99
376_G	382_K	0.504	0.99
362_L	381_M	0.504	0.99
392_A	396_L	0.504	0.99
71_W	74_R	0.504	0.99
224_M	278_L	0.502	0.99
30_W	35_T	0.502	0.99
297_G	327_L	0.502	0.99
396_L	401_T	0.502	0.99
217_S	285_E	0.502	0.99
256_S	260_A	0.501	0.99
93_L	345_M	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rkoM	1	0.9902	100	0.133	Contact Map
4he8M	1	0.9077	100	0.218	Contact Map
3rkoL	1	0.945	100	0.229	Contact Map
4he8L	1	0.9332	100	0.235	Contact Map
3rkoN	1	0.8919	100	0.241	Contact Map
4he8N	1	0.835	100	0.303	Contact Map
3rkoK	1	0.1965	40.2	0.964	Contact Map
4he8K	1	0.1866	31.3	0.966	Contact Map
4b4aA	1	0.2711	6.3	0.975	Contact Map
4he8J	1	0.2927	4.7	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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