NTRC - ECOLI - GREMLIN Contacts

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NTRC - Nitrogen regulation protein NR(I)

UniProt:	P0AFB8	Sequences: MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10385
Length:	469 (440)
Sequences:	9909 (6864)
Seq/√Len:	327.2

ECOLI - NTRC GLRR ATOC ZRAR NORR HYFR FHLA PRPR RTCR YGEV DHAR TYRR
BACSU - YQIR ACOR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
287_R	292_K	3.918	1.00
213_E	223_I	3.625	1.00
169_E	312_R	3.557	1.00
441_T	451_L	3.423	1.00
31_T	48_P	3.389	1.00
286_Q	290_E	2.999	1.00
227_R	262_Y	2.797	1.00
198_A	250_T	2.781	1.00
260_Q	269_P	2.690	1.00
260_Q	271_K	2.648	1.00
16_R	34_E	2.629	1.00
154_I	177_V	2.606	1.00
282_Q	287_R	2.604	1.00
36_G	60_M	2.536	1.00
61_D	64_A	2.491	1.00
431_R	435_T	2.486	1.00
35_N	38_E	2.467	1.00
328_V	361_E	2.463	1.00
261_F	272_V	2.457	1.00
229_E	263_R	2.441	1.00
202_K	247_D	2.439	1.00
228_F	255_V	2.394	1.00
67_K	96_Q	2.341	1.00
447_E	450_R	2.335	1.00
16_R	32_T	2.275	1.00
341_H	377_L	2.259	1.00
441_T	448_A	2.253	1.00
319_P	345_E	2.246	1.00
99_F	118_A	2.241	1.00
156_R	372_A	2.227	1.00
283_N	286_Q	2.225	1.00
34_E	38_E	2.202	1.00
237_F	279_A	2.184	1.00
5_I	29_T	2.134	1.00
262_Y	269_P	2.106	1.00
9_V	39_V	2.084	1.00
340_L	364_C	2.054	1.00
233_G	273_D	2.044	1.00
322_A	340_L	2.037	1.00
287_R	290_E	2.034	1.00
177_V	308_L	2.000	1.00
433_L	437_A	1.999	1.00
319_P	349_T	1.995	1.00
7_W	33_F	1.974	1.00
353_W	363_T	1.963	1.00
213_E	266_G	1.919	1.00
286_Q	289_Q	1.912	1.00
155_G	184_H	1.884	1.00
243_D	282_Q	1.873	1.00
351_L	354_P	1.868	1.00
323_R	345_E	1.849	1.00
20_E	32_T	1.847	1.00
44_A	72_R	1.840	1.00
440_H	451_L	1.833	1.00
143_E	320_R	1.809	1.00
187_R	273_D	1.805	1.00
37_A	59_G	1.781	1.00
40_L	68_Q	1.772	1.00
31_T	42_A	1.734	1.00
257_A	361_E	1.732	1.00
5_I	31_T	1.712	1.00
256_L	276_I	1.705	1.00
315_R	318_I	1.698	1.00
20_E	24_A	1.688	1.00
315_R	319_P	1.684	1.00
324_H	328_V	1.673	1.00
68_Q	71_Q	1.661	1.00
322_A	364_C	1.654	1.00
213_E	263_R	1.645	1.00
339_L	375_E	1.644	1.00
430_E	462_K	1.638	1.00
167_N	307_H	1.630	1.00
228_F	236_L	1.628	1.00
225_Q	229_E	1.611	1.00
50_V	115_V	1.607	1.00
427_P	465_E	1.603	1.00
43_L	69_I	1.589	1.00
167_N	305_R	1.589	1.00
343_E	378_I	1.587	1.00
341_H	344_T	1.582	1.00
73_H	76_L	1.579	1.00
172_T	308_L	1.562	1.00
144_A	316_E	1.559	1.00
26_A	112_V	1.518	1.00
315_R	352_A	1.516	1.00
232_D	272_V	1.503	1.00
212_H	217_F	1.501	1.00
92_S	96_Q	1.501	1.00
351_L	359_Q	1.497	1.00
344_T	348_L	1.489	1.00
266_G	270_V	1.487	1.00
206_E	251_R	1.487	1.00
345_E	349_T	1.480	1.00
457_N	461_R	1.470	1.00
255_V	261_F	1.468	1.00
51_L	69_I	1.459	1.00
124_E	128_P	1.457	1.00
53_S	65_L	1.453	1.00
344_T	378_I	1.451	1.00
278_A	301_L	1.450	1.00
33_F	42_A	1.443	1.00
347_A	378_I	1.433	1.00
437_A	441_T	1.429	1.00
79_I	114_L	1.420	1.00
68_Q	72_R	1.420	1.00
232_D	273_D	1.417	1.00
436_T	440_H	1.409	1.00
377_L	380_D	1.404	1.00
224_R	267_Y	1.399	1.00
332_E	365_R	1.398	1.00
42_A	48_P	1.395	1.00
52_L	115_V	1.393	1.00
150_V	306_V	1.383	1.00
263_R	266_G	1.383	1.00
175_E	254_R	1.376	1.00
157_L	304_I	1.373	1.00
321_L	325_F	1.369	1.00
149_D	152_R	1.363	1.00
242_G	280_T	1.362	1.00
190_A	233_G	1.359	1.00
161_S	332_E	1.354	1.00
376_V	381_L	1.347	1.00
307_H	313_E	1.337	1.00
152_R	155_G	1.336	1.00
147_M	151_F	1.334	1.00
142_G	147_M	1.321	1.00
202_K	245_P	1.311	1.00
340_L	345_E	1.311	1.00
36_G	65_L	1.308	1.00
53_S	80_I	1.305	1.00
229_E	270_V	1.304	1.00
435_T	439_R	1.303	1.00
346_A	350_R	1.300	1.00
35_N	59_G	1.297	1.00
162_I	365_R	1.297	1.00
338_K	374_Q	1.295	1.00
6_V	28_L	1.284	1.00
447_E	451_L	1.280	1.00
31_T	46_K	1.272	1.00
51_L	76_L	1.267	1.00
284_L	293_F	1.266	1.00
22_A	108_I	1.264	1.00
326_L	340_L	1.262	1.00
341_H	375_E	1.262	1.00
344_T	376_V	1.257	1.00
205_I	248_V	1.240	1.00
371_A	380_D	1.240	1.00
57_M	60_M	1.234	1.00
153_I	370_M	1.233	1.00
87_L	91_V	1.227	1.00
28_L	116_E	1.222	1.00
89_A	101_Y	1.221	1.00
261_F	271_K	1.220	1.00
208_E	224_R	1.216	1.00
316_E	349_T	1.215	1.00
329_A	368_T	1.211	1.00
325_F	361_E	1.204	1.00
330_A	338_K	1.196	1.00
285_E	289_Q	1.192	1.00
437_A	451_L	1.186	1.00
323_R	327_Q	1.182	1.00
151_F	154_I	1.182	1.00
128_P	131_V	1.181	1.00
142_G	151_F	1.175	1.00
242_G	284_L	1.173	1.00
55_I	89_A	1.170	1.00
192_F	234_G	1.164	1.00
154_I	180_A	1.163	1.00
327_Q	331_R	1.153	1.00
455_G	458_T	1.151	1.00
66_L	78_V	1.149	1.00
139_D	183_R	1.149	1.00
319_P	322_A	1.148	1.00
425_A	429_L	1.148	1.00
64_A	67_K	1.147	1.00
5_I	46_K	1.141	1.00
140_I	151_F	1.141	1.00
10_D	16_R	1.139	1.00
141_I	324_H	1.138	1.00
289_Q	295_E	1.137	1.00
169_E	310_P	1.136	1.00
326_L	368_T	1.135	1.00
162_I	333_L	1.126	1.00
446_Q	450_R	1.126	1.00
437_A	452_L	1.124	1.00
180_A	184_H	1.124	1.00
127_Q	132_Q	1.122	1.00
179_H	194_A	1.122	1.00
56_R	84_H	1.120	1.00
40_L	60_M	1.119	1.00
445_K	460_T	1.117	1.00
421_L	424_E	1.112	1.00
159_R	186_P	1.109	1.00
315_R	349_T	1.108	1.00
63_L	93_A	1.107	1.00
66_L	80_I	1.107	1.00
343_E	377_L	1.106	1.00
212_H	216_A	1.103	1.00
161_S	187_R	1.100	1.00
150_V	308_L	1.098	1.00
26_A	116_E	1.097	1.00
382_P	385_L	1.097	1.00
461_R	465_E	1.095	1.00
52_L	111_A	1.094	1.00
457_N	460_T	1.093	1.00
458_T	462_K	1.091	1.00
330_A	336_E	1.088	1.00
444_H	447_E	1.085	1.00
207_S	212_H	1.081	1.00
53_S	78_V	1.079	1.00
140_I	177_V	1.077	1.00
325_F	329_A	1.072	1.00
198_A	243_D	1.070	1.00
437_A	448_A	1.070	1.00
212_H	264_V	1.070	1.00
36_G	57_M	1.068	1.00
23_L	115_V	1.063	1.00
422_L	425_A	1.060	1.00
229_E	261_F	1.059	1.00
166_I	277_I	1.056	1.00
432_T	436_T	1.053	1.00
205_I	209_L	1.053	1.00
329_A	364_C	1.048	1.00
50_V	119_I	1.041	1.00
5_I	48_P	1.039	1.00
36_G	40_L	1.039	1.00
422_L	426_Q	1.036	1.00
150_V	177_V	1.034	1.00
154_I	306_V	1.032	1.00
243_D	281_H	1.030	1.00
33_F	39_V	1.027	1.00
154_I	181_L	1.024	1.00
166_I	177_V	1.023	1.00
426_Q	429_L	1.022	1.00
10_D	57_M	1.022	1.00
146_A	149_D	1.021	1.00
232_D	274_V	1.020	1.00
285_E	384_E	1.020	1.00
169_E	172_T	1.017	1.00
259_G	271_K	1.014	1.00
455_G	461_R	1.014	1.00
38_E	41_E	1.009	1.00
429_L	433_L	1.002	1.00
217_F	220_A	1.000	1.00
92_S	95_Q	1.000	1.00
41_E	45_S	0.999	1.00
42_A	46_K	0.999	1.00
165_L	278_A	0.998	1.00
42_A	45_S	0.997	1.00
163_S	259_G	0.996	1.00
235_T	277_I	0.992	1.00
216_A	264_V	0.991	1.00
49_D	122_Y	0.990	1.00
8_V	30_C	0.987	1.00
214_K	222_T	0.985	1.00
263_R	270_V	0.984	1.00
69_I	78_V	0.978	1.00
438_L	448_A	0.974	1.00
444_H	456_R	0.973	1.00
122_Y	126_Q	0.970	1.00
140_I	176_L	0.970	1.00
230_Q	267_Y	0.968	1.00
318_I	322_A	0.965	1.00
145_P	149_D	0.963	1.00
346_A	349_T	0.962	1.00
175_E	194_A	0.960	1.00
162_I	303_V	0.958	1.00
196_N	243_D	0.956	1.00
302_N	305_R	0.956	1.00
446_Q	456_R	0.948	1.00
113_A	117_R	0.947	1.00
318_I	348_L	0.942	1.00
433_L	452_L	0.939	1.00
367_L	371_A	0.935	1.00
67_K	92_S	0.933	1.00
323_R	339_L	0.929	1.00
147_M	150_V	0.921	1.00
330_A	337_A	0.915	1.00
127_Q	131_V	0.912	1.00
367_L	376_V	0.911	1.00
38_E	42_A	0.911	1.00
193_I	231_A	0.910	1.00
124_E	127_Q	0.909	1.00
53_S	57_M	0.907	1.00
434_L	462_K	0.904	1.00
91_V	95_Q	0.903	1.00
164_V	181_L	0.902	1.00
432_T	435_T	0.902	1.00
342_P	345_E	0.901	1.00
65_L	69_I	0.900	1.00
13_S	16_R	0.900	1.00
340_L	376_V	0.899	1.00
438_L	463_L	0.898	1.00
60_M	64_A	0.898	1.00
436_T	439_R	0.897	1.00
434_L	459_L	0.897	1.00
161_S	186_P	0.893	1.00
52_L	79_I	0.892	1.00
120_S	123_Q	0.887	1.00
60_M	68_Q	0.883	1.00
303_V	362_N	0.880	1.00
15_I	106_F	0.880	1.00
41_E	44_A	0.879	1.00
179_H	183_R	0.877	1.00
228_F	274_V	0.875	1.00
50_V	77_P	0.870	1.00
67_K	71_Q	0.869	1.00
150_V	154_I	0.868	1.00
207_S	217_F	0.865	1.00
366_W	370_M	0.857	1.00
244_M	248_V	0.854	1.00
205_I	244_M	0.853	1.00
37_A	41_E	0.850	1.00
435_T	468_M	0.850	1.00
427_P	466_L	0.850	1.00
53_S	69_I	0.847	1.00
148_Q	152_R	0.845	1.00
11_D	54_D	0.843	1.00
325_F	364_C	0.843	1.00
64_A	68_Q	0.842	1.00
141_I	320_R	0.839	1.00
167_N	285_E	0.838	1.00
445_K	452_L	0.838	1.00
120_S	125_Q	0.837	1.00
228_F	272_V	0.837	1.00
194_A	254_R	0.836	1.00
448_A	451_L	0.833	1.00
212_H	220_A	0.831	1.00
35_N	57_M	0.828	1.00
288_V	298_F	0.828	1.00
441_T	447_E	0.827	1.00
124_E	131_V	0.826	1.00
236_L	276_I	0.826	1.00
142_G	177_V	0.826	1.00
225_Q	230_Q	0.825	1.00
438_L	445_K	0.824	1.00
460_T	464_K	0.824	1.00
55_I	80_I	0.823	1.00
142_G	320_R	0.821	1.00
163_S	278_A	0.817	1.00
276_I	301_L	0.817	1.00
445_K	463_L	0.816	1.00
261_F	270_V	0.815	1.00
9_V	65_L	0.815	1.00
458_T	461_R	0.814	1.00
361_E	365_R	0.809	1.00
143_E	148_Q	0.806	1.00
285_E	298_F	0.804	1.00
445_K	457_N	0.803	1.00
95_Q	100_D	0.802	1.00
166_I	308_L	0.801	1.00
302_N	366_W	0.801	1.00
11_D	83_A	0.800	1.00
456_R	460_T	0.798	1.00
319_P	323_R	0.796	1.00
223_I	268_A	0.793	1.00
40_L	65_L	0.790	1.00
33_F	38_E	0.789	1.00
431_R	466_L	0.789	1.00
425_A	428_E	0.788	1.00
340_L	344_T	0.787	1.00
236_L	255_V	0.786	1.00
107_D	110_E	0.781	1.00
148_Q	151_F	0.781	1.00
329_A	361_E	0.780	1.00
66_L	98_A	0.779	1.00
7_W	48_P	0.778	1.00
54_D	104_K	0.771	1.00
196_N	244_M	0.771	1.00
335_V	338_K	0.770	1.00
342_P	346_A	0.770	1.00
19_L	111_A	0.770	1.00
285_E	295_E	0.769	1.00
52_L	81_M	0.766	1.00
212_H	224_R	0.765	1.00
6_V	23_L	0.764	1.00
9_V	51_L	0.764	1.00
37_A	60_M	0.762	1.00
33_F	36_G	0.760	1.00
10_D	15_I	0.760	1.00
439_R	443_G	0.760	1.00
8_V	19_L	0.759	1.00
43_L	51_L	0.759	1.00
193_I	230_Q	0.759	1.00
162_I	304_I	0.757	0.99
454_W	458_T	0.755	0.99
162_I	369_V	0.755	0.99
145_P	148_Q	0.754	0.99
254_R	258_D	0.753	0.99
225_Q	267_Y	0.753	0.99
230_Q	266_G	0.751	0.99
70_K	77_P	0.746	0.99
223_I	263_R	0.744	0.99
11_D	82_T	0.738	0.99
157_L	164_V	0.738	0.99
335_V	368_T	0.738	0.99
88_D	92_S	0.735	0.99
13_S	17_W	0.733	0.99
151_F	177_V	0.733	0.99
201_P	264_V	0.733	0.99
43_L	76_L	0.732	0.99
22_A	112_V	0.731	0.99
151_F	180_A	0.731	0.99
329_A	333_L	0.730	0.99
310_P	313_E	0.729	0.99
347_A	351_L	0.729	0.99
285_E	305_R	0.727	0.99
8_V	20_E	0.727	0.99
63_L	92_S	0.727	0.99
87_L	90_A	0.725	0.99
43_L	73_H	0.725	0.99
338_K	368_T	0.722	0.99
363_T	367_L	0.721	0.99
212_H	223_I	0.717	0.99
116_E	120_S	0.717	0.99
156_R	370_M	0.716	0.99
438_L	443_G	0.715	0.99
62_G	104_K	0.714	0.99
5_I	49_D	0.714	0.99
227_R	230_Q	0.712	0.99
462_K	466_L	0.710	0.99
426_Q	433_L	0.710	0.99
367_L	381_L	0.708	0.99
85_S	103_P	0.706	0.99
434_L	452_L	0.705	0.99
424_E	428_E	0.701	0.99
140_I	147_M	0.699	0.99
318_I	349_T	0.699	0.99
423_S	437_A	0.698	0.99
347_A	381_L	0.698	0.99
146_A	313_E	0.696	0.99
99_F	114_L	0.696	0.99
36_G	59_G	0.694	0.99
55_I	61_D	0.694	0.99
158_S	185_S	0.690	0.99
322_A	345_E	0.689	0.99
298_F	302_N	0.689	0.99
28_L	112_V	0.688	0.99
201_P	204_L	0.688	0.99
11_D	104_K	0.687	0.99
175_E	258_D	0.686	0.99
176_L	180_A	0.686	0.99
228_F	261_F	0.684	0.99
166_I	178_A	0.682	0.99
120_S	124_E	0.681	0.99
459_L	463_L	0.679	0.99
455_G	460_T	0.679	0.99
330_A	335_V	0.678	0.99
19_L	81_M	0.678	0.99
216_A	220_A	0.677	0.99
142_G	154_I	0.676	0.99
77_P	121_H	0.675	0.99
153_I	156_R	0.674	0.99
137_T	184_H	0.673	0.99
81_M	106_F	0.672	0.99
315_R	320_R	0.671	0.99
101_Y	110_E	0.670	0.99
100_D	114_L	0.669	0.99
11_D	62_G	0.667	0.99
382_P	386_F	0.665	0.99
44_A	68_Q	0.664	0.99
428_E	432_T	0.662	0.99
150_V	153_I	0.661	0.99
51_L	78_V	0.661	0.99
322_A	367_L	0.657	0.99
424_E	432_T	0.657	0.99
158_S	184_H	0.656	0.99
152_R	372_A	0.656	0.99
137_T	180_A	0.655	0.99
244_M	252_L	0.655	0.99
285_E	288_V	0.652	0.98
242_G	281_H	0.651	0.98
12_D	15_I	0.651	0.98
53_S	66_L	0.650	0.98
212_H	221_N	0.649	0.98
9_V	57_M	0.644	0.98
13_S	34_E	0.642	0.98
459_L	462_K	0.640	0.98
103_P	110_E	0.640	0.98
434_L	463_L	0.639	0.98
282_Q	292_K	0.638	0.98
54_D	83_A	0.638	0.98
137_T	151_F	0.636	0.98
454_W	462_K	0.634	0.98
77_P	125_Q	0.634	0.98
242_G	282_Q	0.633	0.98
330_A	368_T	0.632	0.98
425_A	433_L	0.632	0.98
443_G	463_L	0.631	0.98
328_V	332_E	0.630	0.98
114_L	118_A	0.630	0.98
237_F	277_I	0.626	0.98
215_G	220_A	0.626	0.98
18_V	22_A	0.626	0.98
178_A	192_F	0.624	0.98
110_E	114_L	0.621	0.98
102_L	106_F	0.619	0.98
242_G	279_A	0.619	0.98
21_R	25_G	0.618	0.98
77_P	122_Y	0.616	0.98
320_R	323_R	0.611	0.98
232_D	271_K	0.611	0.98
110_E	113_A	0.609	0.98
460_T	463_L	0.608	0.98
43_L	48_P	0.608	0.98
143_E	316_E	0.606	0.98
51_L	65_L	0.606	0.98
195_L	236_L	0.604	0.98
156_R	380_D	0.604	0.98
145_P	316_E	0.604	0.98
304_I	370_M	0.601	0.97
421_L	453_G	0.600	0.97
170_S	243_D	0.598	0.97
125_Q	128_P	0.598	0.97
218_T	281_H	0.597	0.97
454_W	459_L	0.597	0.97
363_T	381_L	0.596	0.97
224_R	230_Q	0.595	0.97
359_Q	384_E	0.595	0.97
161_S	333_L	0.594	0.97
224_R	227_R	0.594	0.97
156_R	335_V	0.594	0.97
427_P	431_R	0.593	0.97
329_A	332_E	0.592	0.97
227_R	269_P	0.592	0.97
241_I	301_L	0.590	0.97
85_S	90_A	0.589	0.97
326_L	337_A	0.586	0.97
422_L	429_L	0.586	0.97
85_S	101_Y	0.586	0.97
195_L	227_R	0.585	0.97
82_T	104_K	0.585	0.97
7_W	39_V	0.584	0.97
119_I	122_Y	0.583	0.97
297_L	301_L	0.583	0.97
57_M	62_G	0.582	0.97
106_F	111_A	0.582	0.97
445_K	456_R	0.581	0.97
444_H	460_T	0.581	0.97
329_A	365_R	0.580	0.97
20_E	30_C	0.580	0.97
214_K	221_N	0.579	0.97
48_P	76_L	0.579	0.97
163_S	303_V	0.579	0.97
6_V	119_I	0.579	0.97
128_P	132_Q	0.578	0.97
242_G	293_F	0.577	0.97
39_V	65_L	0.577	0.97
327_Q	337_A	0.576	0.97
363_T	385_L	0.575	0.97
160_S	369_V	0.574	0.97
121_H	125_Q	0.573	0.97
246_L	250_T	0.573	0.97
108_I	112_V	0.571	0.97
333_L	368_T	0.570	0.97
456_R	461_R	0.568	0.96
191_P	230_Q	0.568	0.96
228_F	276_I	0.567	0.96
322_A	326_L	0.566	0.96
218_T	279_A	0.565	0.96
351_L	385_L	0.565	0.96
255_V	258_D	0.565	0.96
461_R	464_K	0.564	0.96
326_L	364_C	0.564	0.96
223_I	266_G	0.564	0.96
187_R	190_A	0.562	0.96
14_S	18_V	0.562	0.96
457_N	464_K	0.561	0.96
214_K	220_A	0.558	0.96
99_F	121_H	0.558	0.96
23_L	30_C	0.557	0.96
90_A	98_A	0.556	0.96
24_A	30_C	0.555	0.96
204_L	218_T	0.555	0.96
422_L	433_L	0.554	0.96
144_A	317_D	0.554	0.96
347_A	385_L	0.553	0.96
62_G	82_T	0.552	0.96
180_A	183_R	0.551	0.96
139_D	180_A	0.551	0.96
337_A	368_T	0.551	0.96
208_E	227_R	0.550	0.96
195_L	209_L	0.549	0.96
213_E	216_A	0.549	0.96
200_I	209_L	0.549	0.96
326_L	330_A	0.548	0.96
89_A	92_S	0.545	0.96
147_M	177_V	0.543	0.95
209_L	248_V	0.543	0.95
196_N	250_T	0.543	0.95
153_I	304_I	0.539	0.95
324_H	327_Q	0.539	0.95
185_S	275_R	0.538	0.95
214_K	223_I	0.538	0.95
316_E	319_P	0.538	0.95
428_E	431_R	0.535	0.95
160_S	333_L	0.534	0.95
259_G	274_V	0.534	0.95
422_L	452_L	0.534	0.95
444_H	448_A	0.533	0.95
159_R	185_S	0.532	0.95
452_L	458_T	0.530	0.95
347_A	382_P	0.529	0.95
6_V	50_V	0.527	0.95
11_D	57_M	0.527	0.95
217_F	224_R	0.526	0.95
69_I	76_L	0.526	0.95
304_I	369_V	0.526	0.95
216_A	223_I	0.525	0.95
113_A	124_E	0.524	0.94
77_P	118_A	0.524	0.94
140_I	180_A	0.523	0.94
311_L	360_L	0.522	0.94
430_E	434_L	0.521	0.94
149_D	153_I	0.520	0.94
39_V	51_L	0.520	0.94
176_L	357_V	0.520	0.94
35_N	58_P	0.519	0.94
232_D	259_G	0.518	0.94
445_K	459_L	0.518	0.94
190_A	232_D	0.518	0.94
9_V	36_G	0.517	0.94
434_L	466_L	0.515	0.94
63_L	89_A	0.515	0.94
229_E	232_D	0.514	0.94
17_W	20_E	0.514	0.94
8_V	32_T	0.514	0.94
457_N	462_K	0.513	0.94
40_L	44_A	0.513	0.94
130_N	133_L	0.511	0.94
87_L	103_P	0.511	0.94
320_R	324_H	0.511	0.94
161_S	273_D	0.511	0.94
117_R	124_E	0.510	0.94
196_N	199_A	0.510	0.94
83_A	104_K	0.509	0.94
452_L	462_K	0.508	0.94
62_G	83_A	0.508	0.94
347_A	350_R	0.508	0.94
213_E	270_V	0.506	0.93
423_S	426_Q	0.506	0.93
315_R	350_R	0.506	0.93
134_N	137_T	0.505	0.93
172_T	176_L	0.505	0.93
344_T	367_L	0.505	0.93
70_K	75_M	0.504	0.93
207_S	215_G	0.504	0.93
55_I	106_F	0.504	0.93
433_L	445_K	0.504	0.93
222_T	267_Y	0.503	0.93
242_G	287_R	0.503	0.93
343_E	346_A	0.503	0.93
56_R	86_D	0.502	0.93
24_A	29_T	0.501	0.93
248_V	251_R	0.501	0.93
255_V	272_V	0.501	0.93
88_D	110_E	0.500	0.93
261_F	269_P	0.500	0.93
197_M	205_I	0.500	0.93
423_S	462_K	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.8124	100	0.122	Contact Map
3dzdA	2	0.7846	100	0.286	Contact Map
1ojlA	3	0.6418	100	0.465	Contact Map
4fwgA	3	0.6226	100	0.631	Contact Map
1r6bX	1	0.8252	100	0.662	Contact Map
3pxiA	3	0.7719	100	0.667	Contact Map
1qvrA	3	0.806	100	0.668	Contact Map
4qhsA	3	0.5203	100	0.674	Contact Map
4ciuA	1	0.8038	100	0.675	Contact Map
4qosA	1	0.5117	100	0.676	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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