NARX - ECOLI - GREMLIN Contacts

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NARX - Nitrate/nitrite sensor protein NarX

UniProt:	P0AFA2	Sequences: MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10646
Length:	598 (508)
Sequences:	6149 (5468)
Seq/√Len:	242.6

ECOLI - NARX NARQ ATOS BARA TORS DPIB DCUS RCSD RCSC ARCB GLRK
BACSU - YYCG RESE PHOR CITS DCTS KINE MALK KINA KINC
HALSA - Q9HQG5 Q9HQ16

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
413_V	434_I	4.496	1.00
535_Q	578_E	4.355	1.00
572_R	575_G	4.149	1.00
191_A	196_D	4.038	1.00
514_S	537_N	3.730	1.00
569_V	579_V	3.516	1.00
423_L	427_S	3.211	1.00
207_N	210_A	3.125	1.00
366_V	369_L	2.976	1.00
568_R	580_V	2.945	1.00
263_P	267_R	2.888	1.00
532_L	581_V	2.877	1.00
522_T	533_T	2.869	1.00
502_I	559_R	2.824	1.00
546_I	569_V	2.804	1.00
502_I	560_A	2.735	1.00
481_K	518_E	2.733	1.00
473_S	476_F	2.725	1.00
557_R	561_Q	2.724	1.00
529_Q	582_T	2.692	1.00
494_H	563_L	2.675	1.00
520_V	535_Q	2.598	1.00
560_A	581_V	2.590	1.00
245_N	249_S	2.589	1.00
364_T	369_L	2.570	1.00
518_E	537_N	2.532	1.00
460_G	463_P	2.502	1.00
556_M	567_C	2.496	1.00
459_P	494_H	2.493	1.00
526_N	531_K	2.486	1.00
342_G	349_P	2.471	1.00
342_G	347_T	2.462	1.00
533_T	578_E	2.420	1.00
417_Q	432_S	2.394	1.00
571_R	577_T	2.372	1.00
205_G	210_A	2.346	1.00
522_T	535_Q	2.269	1.00
524_A	531_K	2.269	1.00
570_R	578_E	2.261	1.00
462_R	523_V	2.256	1.00
90_A	93_D	2.236	1.00
541_V	545_A	2.234	1.00
423_L	426_S	2.217	1.00
14_Q	207_N	2.196	1.00
533_T	580_V	2.189	1.00
478_F	482_L	2.182	1.00
531_K	582_T	2.170	1.00
288_V	294_E	2.147	1.00
483_D	522_T	2.131	1.00
560_A	565_G	2.109	1.00
559_R	563_L	2.099	1.00
200_R	217_N	2.093	1.00
365_L	369_L	2.091	1.00
260_S	275_L	2.074	1.00
90_A	94_G	2.062	1.00
364_T	367_E	2.060	1.00
514_S	517_S	2.053	1.00
260_S	268_L	1.973	1.00
327_G	330_L	1.954	1.00
510_A	519_V	1.929	1.00
571_R	575_G	1.926	1.00
481_K	520_V	1.920	1.00
424_P	427_S	1.920	1.00
200_R	224_A	1.915	1.00
410_K	438_L	1.914	1.00
198_T	224_A	1.901	1.00
390_E	396_R	1.874	1.00
530_V	585_P	1.852	1.00
342_G	345_L	1.850	1.00
249_S	253_Q	1.838	1.00
531_K	580_V	1.833	1.00
571_R	574_S	1.796	1.00
258_L	272_L	1.779	1.00
417_Q	435_R	1.771	1.00
536_D	540_G	1.763	1.00
192_V	220_S	1.763	1.00
502_I	556_M	1.762	1.00
258_L	278_L	1.751	1.00
274_G	277_N	1.751	1.00
524_A	533_T	1.743	1.00
86_L	90_A	1.736	1.00
410_K	439_N	1.727	1.00
108_N	112_P	1.723	1.00
57_S	60_L	1.711	1.00
288_V	291_T	1.696	1.00
260_S	272_L	1.693	1.00
542_P	545_A	1.693	1.00
189_A	219_M	1.690	1.00
130_F	134_L	1.690	1.00
483_D	520_V	1.675	1.00
329_T	333_R	1.671	1.00
517_S	537_N	1.658	1.00
91_E	94_G	1.657	1.00
494_H	499_L	1.656	1.00
525_Q	585_P	1.652	1.00
244_K	247_I	1.648	1.00
467_A	500_L	1.642	1.00
508_S	512_K	1.632	1.00
109_E	112_P	1.623	1.00
281_L	285_E	1.619	1.00
329_T	332_W	1.609	1.00
364_T	368_Q	1.600	1.00
216_L	219_M	1.591	1.00
498_H	501_Q	1.584	1.00
46_A	49_K	1.559	1.00
417_Q	428_R	1.558	1.00
409_M	434_I	1.557	1.00
87_T	94_G	1.538	1.00
566_D	582_T	1.536	1.00
259_H	272_L	1.523	1.00
54_R	57_S	1.521	1.00
192_V	219_M	1.514	1.00
200_R	220_S	1.505	1.00
503_A	532_L	1.502	1.00
514_S	519_V	1.500	1.00
408_C	437_E	1.471	1.00
390_E	397_E	1.468	1.00
570_R	580_V	1.463	1.00
185_L	216_L	1.461	1.00
327_G	332_W	1.432	1.00
349_P	364_T	1.421	1.00
546_I	571_R	1.413	1.00
344_L	347_T	1.397	1.00
479_P	518_E	1.383	1.00
561_Q	566_D	1.376	1.00
171_I	175_R	1.367	1.00
342_G	348_L	1.364	1.00
542_P	573_E	1.358	1.00
485_Q	488_P	1.356	1.00
345_L	349_P	1.353	1.00
200_R	221_A	1.347	1.00
258_L	262_A	1.345	1.00
495_Q	498_H	1.341	1.00
86_L	91_E	1.326	1.00
432_S	436_N	1.326	1.00
498_H	559_R	1.307	1.00
403_A	441_S	1.302	1.00
255_N	259_H	1.300	1.00
416_L	427_S	1.299	1.00
49_K	53_L	1.296	1.00
391_R	394_I	1.295	1.00
137_L	141_F	1.293	1.00
345_L	348_L	1.288	1.00
569_V	577_T	1.284	1.00
520_V	537_N	1.280	1.00
289_Y	294_E	1.275	1.00
258_L	261_R	1.274	1.00
105_Y	108_N	1.274	1.00
99_L	102_L	1.273	1.00
242_E	245_N	1.271	1.00
503_A	534_V	1.269	1.00
412_Q	430_L	1.264	1.00
386_I	396_R	1.264	1.00
266_E	272_L	1.259	1.00
394_I	397_E	1.247	1.00
541_V	577_T	1.244	1.00
86_L	94_G	1.243	1.00
273_N	277_N	1.230	1.00
272_L	275_L	1.227	1.00
392_A	396_R	1.223	1.00
460_G	491_V	1.216	1.00
331_K	342_G	1.210	1.00
261_R	272_L	1.203	1.00
87_T	91_E	1.201	1.00
343_I	346_A	1.201	1.00
472_Y	511_L	1.195	1.00
502_I	581_V	1.194	1.00
178_L	181_P	1.190	1.00
503_A	507_L	1.188	1.00
565_G	583_F	1.188	1.00
543_E	546_I	1.184	1.00
98_Q	101_G	1.180	1.00
290_D	294_E	1.179	1.00
189_A	216_L	1.177	1.00
252_W	270_P	1.174	1.00
271_V	276_Q	1.173	1.00
343_I	347_T	1.173	1.00
276_Q	283_D	1.171	1.00
396_R	404_Q	1.170	1.00
53_L	56_Q	1.169	1.00
478_F	488_P	1.169	1.00
344_L	348_L	1.168	1.00
382_Q	386_I	1.162	1.00
45_H	49_K	1.161	1.00
102_L	109_E	1.151	1.00
506_A	556_M	1.146	1.00
393_T	397_E	1.142	1.00
57_S	61_L	1.141	1.00
471_E	504_R	1.136	1.00
465_L	503_A	1.135	1.00
206_R	210_A	1.133	1.00
95_Q	99_L	1.131	1.00
461_L	532_L	1.127	1.00
289_Y	293_D	1.125	1.00
412_Q	433_Q	1.124	1.00
501_Q	559_R	1.122	1.00
443_A	497_I	1.116	1.00
499_L	581_V	1.109	1.00
448_L	452_F	1.106	1.00
442_W	446_R	1.105	1.00
288_V	296_N	1.103	1.00
290_D	293_D	1.092	1.00
560_A	583_F	1.091	1.00
189_A	212_L	1.090	1.00
217_N	220_S	1.089	1.00
188_M	201_A	1.086	1.00
393_T	396_R	1.083	1.00
459_P	464_A	1.082	1.00
499_L	563_L	1.080	1.00
61_L	64_V	1.075	1.00
408_C	412_Q	1.071	1.00
328_T	331_K	1.071	1.00
333_R	340_Q	1.070	1.00
128_S	133_G	1.070	1.00
499_L	503_A	1.068	1.00
386_I	397_E	1.067	1.00
507_L	521_V	1.066	1.00
478_F	486_L	1.060	1.00
186_L	211_M	1.058	1.00
467_A	496_A	1.057	1.00
529_Q	566_D	1.057	1.00
389_E	397_E	1.054	1.00
104_D	108_N	1.053	1.00
129_Q	134_L	1.049	1.00
244_K	248_L	1.048	1.00
288_V	293_D	1.046	1.00
245_N	248_L	1.044	1.00
248_L	252_W	1.044	1.00
128_S	132_A	1.042	1.00
201_A	217_N	1.042	1.00
252_W	272_L	1.039	1.00
106_W	110_L	1.037	1.00
342_G	346_A	1.032	1.00
219_M	223_L	1.029	1.00
271_V	275_L	1.027	1.00
437_E	440_A	1.026	1.00
568_R	582_T	1.025	1.00
388_M	397_E	1.025	1.00
74_I	80_T	1.023	1.00
506_A	579_V	1.023	1.00
331_K	337_S	1.021	1.00
492_P	583_F	1.019	1.00
388_M	396_R	1.016	1.00
390_E	395_A	1.015	1.00
388_M	392_A	1.013	1.00
506_A	581_V	1.013	1.00
190_S	194_H	1.011	1.00
77_M	80_T	1.009	1.00
526_N	582_T	1.005	1.00
74_I	78_E	1.002	1.00
100_Q	105_Y	0.992	1.00
185_L	189_A	0.992	1.00
291_T	294_E	0.991	1.00
269_S	272_L	0.990	1.00
502_I	563_L	0.988	1.00
396_R	405_S	0.987	1.00
385_L	389_E	0.978	1.00
416_L	431_L	0.974	1.00
263_P	272_L	0.974	1.00
129_Q	132_A	0.973	1.00
465_L	521_V	0.973	1.00
299_E	302_C	0.973	1.00
186_L	215_A	0.970	1.00
273_N	276_Q	0.970	1.00
188_M	216_L	0.966	1.00
98_Q	102_L	0.964	1.00
254_A	272_L	0.963	1.00
75_K	78_E	0.962	1.00
441_S	446_R	0.960	1.00
541_V	553_M	0.958	1.00
379_Q	382_Q	0.958	1.00
472_Y	504_R	0.955	1.00
329_T	342_G	0.955	1.00
473_S	478_F	0.950	1.00
241_L	244_K	0.946	1.00
328_T	333_R	0.945	1.00
81_A	84_A	0.945	1.00
106_W	109_E	0.944	1.00
560_A	567_C	0.944	1.00
386_I	404_Q	0.943	1.00
327_G	349_P	0.943	1.00
398_L	451_T	0.942	1.00
49_K	52_S	0.941	1.00
406_L	438_L	0.940	1.00
391_R	396_R	0.940	1.00
346_A	349_P	0.936	1.00
336_D	340_Q	0.934	1.00
484_Y	523_V	0.934	1.00
10_T	13_N	0.931	1.00
389_E	396_R	0.925	1.00
78_E	81_A	0.917	1.00
390_E	394_I	0.913	1.00
268_L	272_L	0.908	1.00
344_L	349_P	0.907	1.00
108_N	111_I	0.905	1.00
411_M	415_C	0.905	1.00
87_T	90_A	0.901	1.00
330_L	333_R	0.899	1.00
392_A	397_E	0.898	1.00
74_I	77_M	0.898	1.00
127_V	134_L	0.894	1.00
106_W	112_P	0.894	1.00
413_V	435_R	0.893	1.00
397_E	404_Q	0.891	1.00
461_L	530_V	0.890	1.00
404_Q	513_H	0.889	1.00
105_Y	111_I	0.887	1.00
212_L	219_M	0.887	1.00
128_S	134_L	0.886	1.00
331_K	348_L	0.886	1.00
252_W	259_H	0.885	1.00
387_V	390_E	0.884	1.00
329_T	347_T	0.883	0.99
192_V	195_R	0.882	0.99
390_E	513_H	0.881	0.99
543_E	572_R	0.880	0.99
465_L	523_V	0.879	0.99
207_N	213_G	0.877	0.99
541_V	546_I	0.875	0.99
189_A	215_A	0.873	0.99
99_L	106_W	0.869	0.99
450_T	498_H	0.866	0.99
45_H	48_N	0.865	0.99
397_E	441_S	0.865	0.99
487_P	525_Q	0.864	0.99
413_V	417_Q	0.864	0.99
413_V	431_L	0.861	0.99
468_S	500_L	0.852	0.99
224_A	228_A	0.851	0.99
333_R	342_G	0.849	0.99
332_W	344_L	0.848	0.99
381_R	384_Q	0.842	0.99
125_A	128_S	0.841	0.99
282_R	285_E	0.841	0.99
386_I	394_I	0.840	0.99
397_E	403_A	0.838	0.99
196_D	199_Q	0.837	0.99
59_R	63_A	0.835	0.99
447_E	549_N	0.834	0.99
332_W	342_G	0.832	0.99
392_A	512_K	0.832	0.99
505_E	549_N	0.831	0.99
216_L	220_S	0.830	0.99
201_A	213_G	0.830	0.99
408_C	433_Q	0.828	0.99
50_A	53_L	0.827	0.99
285_E	288_V	0.826	0.99
410_K	442_W	0.825	0.99
413_V	438_L	0.823	0.99
291_T	296_N	0.823	0.99
107_R	112_P	0.823	0.99
103_Q	107_R	0.821	0.99
262_A	268_L	0.819	0.99
383_Q	386_I	0.819	0.99
134_L	141_F	0.817	0.99
409_M	438_L	0.817	0.99
90_A	95_Q	0.817	0.99
479_P	482_L	0.816	0.99
176_A	180_Q	0.816	0.99
403_A	442_W	0.812	0.99
248_L	251_L	0.812	0.99
332_W	346_A	0.812	0.99
441_S	450_T	0.810	0.99
125_A	129_Q	0.809	0.99
437_E	448_L	0.808	0.99
437_E	449_L	0.807	0.99
342_G	364_T	0.804	0.99
280_L	285_E	0.803	0.99
331_K	343_I	0.800	0.99
332_W	340_Q	0.798	0.99
167_L	171_I	0.796	0.99
438_L	441_S	0.795	0.99
130_F	133_G	0.793	0.99
42_G	46_A	0.793	0.99
365_L	368_Q	0.792	0.99
104_D	107_R	0.791	0.99
129_Q	133_G	0.789	0.99
327_G	333_R	0.788	0.99
463_P	467_A	0.788	0.99
451_T	558_D	0.787	0.99
99_L	107_R	0.787	0.99
190_S	211_M	0.786	0.99
384_Q	388_M	0.785	0.99
476_F	480_V	0.784	0.99
213_G	217_N	0.783	0.99
404_Q	555_I	0.783	0.99
391_R	398_L	0.782	0.99
434_I	438_L	0.781	0.99
390_E	404_Q	0.780	0.99
462_R	484_Y	0.780	0.99
263_P	266_E	0.779	0.99
404_Q	411_M	0.778	0.99
506_A	534_V	0.777	0.99
78_E	84_A	0.777	0.99
78_E	82_F	0.777	0.99
128_S	131_V	0.776	0.99
389_E	393_T	0.774	0.99
42_G	45_H	0.774	0.99
32_V	36_L	0.774	0.99
103_Q	112_P	0.773	0.99
414_S	435_R	0.772	0.99
396_R	403_A	0.772	0.99
222_E	225_E	0.770	0.99
276_Q	282_R	0.769	0.99
488_P	523_V	0.769	0.99
568_R	581_V	0.769	0.99
188_M	199_Q	0.766	0.99
565_G	584_I	0.766	0.99
394_I	398_L	0.765	0.99
462_R	466_E	0.765	0.99
498_H	502_I	0.763	0.99
44_A	48_N	0.762	0.99
289_Y	292_D	0.762	0.99
130_F	136_Q	0.761	0.99
186_L	190_S	0.760	0.98
490_L	525_Q	0.760	0.98
293_D	296_N	0.760	0.98
76_E	80_T	0.759	0.98
98_Q	107_R	0.756	0.98
395_A	404_Q	0.756	0.98
175_R	179_L	0.751	0.98
60_L	64_V	0.750	0.98
387_V	392_A	0.750	0.98
122_T	126_D	0.750	0.98
103_Q	106_W	0.748	0.98
394_I	407_S	0.748	0.98
268_L	275_L	0.747	0.98
99_L	103_Q	0.747	0.98
449_L	512_K	0.745	0.98
242_E	246_Q	0.745	0.98
433_Q	437_E	0.744	0.98
136_Q	141_F	0.740	0.98
145_T	149_I	0.739	0.98
296_N	301_T	0.739	0.98
165_L	169_F	0.738	0.98
132_A	136_Q	0.738	0.98
396_R	513_H	0.737	0.98
405_S	441_S	0.737	0.98
76_E	83_S	0.736	0.98
484_Y	488_P	0.736	0.98
60_L	63_A	0.735	0.98
100_Q	106_W	0.735	0.98
33_S	37_V	0.735	0.98
395_A	398_L	0.734	0.98
34_G	38_Q	0.734	0.98
397_E	512_K	0.732	0.98
11_L	178_L	0.730	0.98
466_E	470_E	0.729	0.98
441_S	448_L	0.727	0.98
448_L	453_R	0.726	0.98
429_E	433_Q	0.726	0.98
416_L	434_I	0.725	0.98
387_V	391_R	0.723	0.98
121_E	124_S	0.723	0.98
102_L	105_Y	0.723	0.98
76_E	79_Q	0.721	0.98
390_E	512_K	0.717	0.98
500_L	504_R	0.717	0.98
397_E	513_H	0.716	0.98
275_L	279_T	0.716	0.98
391_R	397_E	0.711	0.98
189_A	193_S	0.711	0.98
407_S	410_K	0.711	0.98
220_S	223_L	0.710	0.98
99_L	109_E	0.710	0.98
47_I	50_A	0.707	0.98
227_Y	230_L	0.707	0.98
388_M	455_Q	0.706	0.98
272_L	280_L	0.705	0.98
105_Y	109_E	0.704	0.98
341_Y	346_A	0.704	0.98
185_L	213_G	0.704	0.98
408_C	451_T	0.703	0.98
388_M	394_I	0.703	0.98
340_Q	343_I	0.701	0.97
425_E	428_R	0.700	0.97
131_V	134_L	0.697	0.97
387_V	393_T	0.696	0.97
102_L	106_W	0.695	0.97
396_R	441_S	0.695	0.97
82_F	85_E	0.693	0.97
386_I	390_E	0.692	0.97
475_K	478_F	0.692	0.97
468_S	507_L	0.690	0.97
333_R	336_D	0.690	0.97
78_E	85_E	0.689	0.97
392_A	454_L	0.689	0.97
394_I	404_Q	0.689	0.97
263_P	269_S	0.688	0.97
405_S	555_I	0.686	0.97
390_E	393_T	0.686	0.97
226_S	230_L	0.685	0.97
451_T	554_I	0.682	0.97
392_A	513_H	0.681	0.97
327_G	331_K	0.681	0.97
190_S	218_N	0.680	0.97
465_L	532_L	0.680	0.97
127_V	130_F	0.678	0.97
424_P	428_R	0.676	0.97
449_L	549_N	0.671	0.97
546_I	579_V	0.670	0.97
250_F	253_Q	0.670	0.97
328_T	332_W	0.669	0.97
86_L	89_A	0.669	0.97
390_E	403_A	0.668	0.97
421_D	427_S	0.667	0.97
272_L	284_I	0.666	0.97
28_A	32_V	0.666	0.97
46_A	50_A	0.665	0.97
79_Q	83_S	0.664	0.96
468_S	471_E	0.664	0.96
392_A	501_Q	0.663	0.96
130_F	135_D	0.663	0.96
261_R	270_P	0.662	0.96
54_R	58_Y	0.661	0.96
451_T	513_H	0.661	0.96
388_M	398_L	0.660	0.96
343_I	348_L	0.658	0.96
271_V	286_L	0.658	0.96
387_V	394_I	0.658	0.96
87_T	93_D	0.658	0.96
501_Q	555_I	0.657	0.96
539_C	577_T	0.657	0.96
478_F	485_Q	0.656	0.96
438_L	442_W	0.656	0.96
348_L	364_T	0.656	0.96
332_W	336_D	0.655	0.96
55_M	59_R	0.653	0.96
47_I	51_G	0.650	0.96
397_E	557_R	0.649	0.96
503_A	581_V	0.649	0.96
107_R	111_I	0.649	0.96
382_Q	397_E	0.648	0.96
404_Q	512_K	0.647	0.96
122_T	125_A	0.646	0.96
384_Q	387_V	0.646	0.96
581_V	584_I	0.645	0.96
473_S	480_V	0.644	0.96
42_G	50_A	0.643	0.96
87_T	92_R	0.643	0.96
56_Q	61_L	0.642	0.96
340_Q	347_T	0.641	0.96
257_R	348_L	0.641	0.96
328_T	334_L	0.639	0.96
127_V	133_G	0.638	0.96
260_S	280_L	0.638	0.96
104_D	109_E	0.637	0.96
298_Q	302_C	0.637	0.96
100_Q	103_Q	0.636	0.96
257_R	274_G	0.633	0.95
386_I	391_R	0.632	0.95
485_Q	524_A	0.632	0.95
175_R	178_L	0.632	0.95
329_T	336_D	0.630	0.95
505_E	556_M	0.630	0.95
528_N	585_P	0.629	0.95
496_A	500_L	0.628	0.95
127_V	131_V	0.628	0.95
464_A	468_S	0.627	0.95
394_I	448_L	0.627	0.95
290_D	296_N	0.626	0.95
103_Q	108_N	0.625	0.95
102_L	111_I	0.624	0.95
396_R	454_L	0.623	0.95
287_R	290_D	0.623	0.95
412_Q	434_I	0.622	0.95
134_L	138_V	0.621	0.95
419_Q	427_S	0.620	0.95
419_Q	430_L	0.620	0.95
331_K	336_D	0.619	0.95
122_T	128_S	0.617	0.95
523_V	532_L	0.616	0.95
477_G	484_Y	0.615	0.95
410_K	413_V	0.614	0.95
258_L	279_T	0.614	0.95
95_Q	98_Q	0.614	0.95
102_L	107_R	0.613	0.95
327_G	336_D	0.613	0.95
383_Q	394_I	0.613	0.95
437_E	442_W	0.613	0.95
89_A	93_D	0.613	0.95
197_F	223_L	0.612	0.94
181_P	208_E	0.611	0.94
272_L	276_Q	0.611	0.94
445_L	451_T	0.611	0.94
334_L	340_Q	0.611	0.94
403_A	412_Q	0.610	0.94
101_G	106_W	0.610	0.94
98_Q	109_E	0.610	0.94
261_R	275_L	0.609	0.94
297_H	300_F	0.609	0.94
490_L	585_P	0.608	0.94
88_R	93_D	0.608	0.94
293_D	299_E	0.606	0.94
407_S	412_Q	0.606	0.94
435_R	439_N	0.606	0.94
107_R	110_L	0.605	0.94
36_L	39_G	0.605	0.94
103_Q	109_E	0.604	0.94
441_S	449_L	0.603	0.94
338_H	343_I	0.602	0.94
436_N	467_A	0.601	0.94
53_L	57_S	0.601	0.94
397_E	514_S	0.600	0.94
218_N	222_E	0.599	0.94
101_G	105_Y	0.599	0.94
121_E	126_D	0.599	0.94
465_L	482_L	0.598	0.94
98_Q	106_W	0.598	0.94
551_Y	555_I	0.597	0.94
403_A	512_K	0.597	0.94
196_D	200_R	0.596	0.94
533_T	581_V	0.593	0.94
440_A	444_Q	0.593	0.94
259_H	263_P	0.591	0.93
75_K	81_A	0.591	0.93
443_A	447_E	0.589	0.93
513_H	539_C	0.588	0.93
487_P	490_L	0.587	0.93
392_A	404_Q	0.586	0.93
403_A	446_R	0.586	0.93
331_K	335_A	0.585	0.93
43_S	50_A	0.585	0.93
98_Q	108_N	0.584	0.93
258_L	275_L	0.583	0.93
80_T	84_A	0.582	0.93
505_E	548_S	0.582	0.93
341_Y	347_T	0.582	0.93
292_D	297_H	0.581	0.93
437_E	441_S	0.581	0.93
133_G	136_Q	0.579	0.93
132_A	135_D	0.578	0.93
80_T	83_S	0.577	0.93
406_L	512_K	0.576	0.93
398_L	412_Q	0.575	0.92
343_I	349_P	0.574	0.92
293_D	300_F	0.573	0.92
380_E	407_S	0.573	0.92
99_L	108_N	0.570	0.92
514_S	539_C	0.570	0.92
404_Q	408_C	0.569	0.92
225_E	229_V	0.569	0.92
210_A	213_G	0.568	0.92
329_T	348_L	0.567	0.92
483_D	524_A	0.566	0.92
19_V	22_S	0.566	0.92
498_H	562_S	0.565	0.92
100_Q	107_R	0.565	0.92
444_Q	452_F	0.563	0.92
393_T	404_Q	0.561	0.92
331_K	349_P	0.561	0.92
405_S	445_L	0.560	0.91
54_R	60_L	0.560	0.91
260_S	266_E	0.560	0.91
391_R	451_T	0.559	0.91
252_W	255_N	0.559	0.91
485_Q	522_T	0.559	0.91
469_C	472_Y	0.559	0.91
252_W	258_L	0.558	0.91
334_L	341_Y	0.557	0.91
272_L	288_V	0.554	0.91
56_Q	59_R	0.553	0.91
403_A	449_L	0.553	0.91
252_W	261_R	0.552	0.91
58_Y	62_A	0.552	0.91
106_W	111_I	0.552	0.91
98_Q	112_P	0.552	0.91
208_E	213_G	0.552	0.91
330_L	334_L	0.551	0.91
412_Q	437_E	0.551	0.91
102_L	108_N	0.551	0.91
49_K	54_R	0.549	0.91
393_T	452_F	0.548	0.91
332_W	349_P	0.548	0.91
338_H	347_T	0.547	0.91
181_P	219_M	0.547	0.91
416_L	433_Q	0.547	0.91
259_H	266_E	0.546	0.90
223_L	227_Y	0.546	0.90
441_S	513_H	0.545	0.90
133_G	141_F	0.545	0.90
98_Q	103_Q	0.544	0.90
407_S	411_M	0.544	0.90
240_G	244_K	0.544	0.90
80_T	85_E	0.544	0.90
391_R	449_L	0.543	0.90
284_I	287_R	0.543	0.90
498_H	563_L	0.543	0.90
191_A	199_Q	0.543	0.90
539_C	571_R	0.542	0.90
31_A	35_W	0.541	0.90
294_E	298_Q	0.540	0.90
398_L	404_Q	0.540	0.90
74_I	81_A	0.540	0.90
420_G	427_S	0.538	0.90
392_A	514_S	0.538	0.90
380_E	386_I	0.537	0.90
382_Q	392_A	0.537	0.90
406_L	412_Q	0.536	0.90
393_T	398_L	0.536	0.90
252_W	260_S	0.534	0.89
407_S	437_E	0.533	0.89
268_L	271_V	0.533	0.89
333_R	346_A	0.532	0.89
407_S	442_W	0.532	0.89
123_V	126_D	0.531	0.89
411_M	455_Q	0.531	0.89
567_C	579_V	0.530	0.89
393_T	430_L	0.530	0.89
404_Q	551_Y	0.530	0.89
247_I	270_P	0.529	0.89
213_G	216_L	0.529	0.89
333_R	343_I	0.529	0.89
174_L	178_L	0.528	0.89
415_C	430_L	0.527	0.89
386_I	393_T	0.527	0.89
404_Q	441_S	0.526	0.89
380_E	384_Q	0.526	0.89
181_P	207_N	0.525	0.89
295_E	300_F	0.524	0.89
255_N	258_L	0.523	0.88
261_R	268_L	0.523	0.88
208_E	212_L	0.521	0.88
36_L	40_V	0.521	0.88
387_V	396_R	0.520	0.88
333_R	339_T	0.518	0.88
394_I	441_S	0.517	0.88
143_R	147_M	0.515	0.88
391_R	395_A	0.515	0.88
405_S	444_Q	0.515	0.88
330_L	348_L	0.515	0.88
297_H	301_T	0.515	0.88
137_L	140_G	0.514	0.88
473_S	519_V	0.514	0.88
390_E	514_S	0.513	0.88
404_Q	514_S	0.513	0.88
395_A	437_E	0.513	0.88
295_E	299_E	0.512	0.87
57_S	64_V	0.511	0.87
380_E	383_Q	0.510	0.87
382_Q	396_R	0.509	0.87
414_S	438_L	0.509	0.87
336_D	339_T	0.509	0.87
336_D	349_P	0.508	0.87
50_A	54_R	0.508	0.87
396_R	512_K	0.507	0.87
329_T	334_L	0.507	0.87
105_Y	110_L	0.507	0.87
396_R	451_T	0.506	0.87
408_C	411_M	0.506	0.87
387_V	403_A	0.505	0.87
469_C	482_L	0.504	0.87
405_S	505_E	0.504	0.87
386_I	389_E	0.503	0.87
384_Q	390_E	0.503	0.87
288_V	298_Q	0.502	0.86
71_K	75_K	0.502	0.86
276_Q	280_L	0.502	0.86
448_L	500_L	0.502	0.86
99_L	112_P	0.502	0.86
541_V	579_V	0.501	0.86
240_G	243_H	0.500	0.86

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.612	100	0.468	Contact Map
4gczA	2	0.5836	100	0.562	Contact Map
3a0rA	2	0.5201	100	0.564	Contact Map
4r3aA	1	0.5084	100	0.624	Contact Map
4bixA	2	0.3495	100	0.627	Contact Map
4ctiA	2	0.3746	100	0.643	Contact Map
4r39A	1	0.3428	100	0.657	Contact Map
3d36A	2	0.3395	100	0.66	Contact Map
2c2aA	2	0.3579	100	0.663	Contact Map
4q20A	2	0.3478	100	0.666	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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