GREMLIN Database
RIDA - 2-iminobutanoate/2-iminopropanoate deaminase
UniProt: P0AF93 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12524
Length: 128 (115)
Sequences: 6550 (4255)
Seq/√Len: 396.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
51_R93_A3.2181.00
58_K68_V2.8751.00
66_L70_D2.7491.00
45_D48_A2.6061.00
73_K122_E2.4711.00
47_A86_T2.3961.00
77_F108_V2.1181.00
76_V87_V2.1121.00
51_R55_D2.0441.00
109_E112_R2.0211.00
47_A89_A1.9971.00
55_D94_F1.9491.00
33_I117_V1.8821.00
58_K62_E1.7691.00
61_V125_A1.7551.00
49_Q118_K1.7471.00
57_V123_A1.7291.00
83_D118_K1.6261.00
51_R94_F1.6071.00
52_Q56_N1.6071.00
112_R116_D1.6051.00
27_I66_L1.5761.00
74_T123_A1.5531.00
23_L72_V1.4971.00
78_V87_V1.4941.00
67_K70_D1.4701.00
81_L109_E1.4681.00
36_N39_T1.4671.00
34_P117_V1.4411.00
36_N40_G1.4391.00
55_D58_K1.4281.00
97_E101_T1.4241.00
46_V50_A1.4131.00
106_S122_E1.3211.00
23_L126_V1.3161.00
88_N105_R1.3051.00
52_Q55_D1.2881.00
78_V107_C1.2751.00
28_I124_I1.2631.00
31_G120_E1.2611.00
22_D25_N1.2561.00
29_T60_I1.2191.00
79_K83_D1.2151.00
86_T89_A1.2061.00
91_Y105_R1.1771.00
71_I123_A1.1661.00
41_E115_K1.1581.00
90_T93_A1.1271.00
83_D86_T1.1231.00
22_D27_I1.1221.00
61_V66_L1.1111.00
10_A19_Q1.1101.00
96_T101_T1.0851.00
27_I64_A1.0781.00
9_N62_E1.0751.00
29_T123_A1.0681.00
26_M126_V1.0551.00
34_P53_S1.0371.00
77_F110_V1.0291.00
51_R90_T1.0181.00
79_K112_R1.0161.00
50_A87_V1.0091.00
89_A92_E1.0081.00
96_T102_F1.0051.00
22_D66_L1.0031.00
71_I95_F0.9851.00
26_M72_V0.9741.00
75_T122_E0.9711.00
43_P48_A0.9681.00
77_F106_S0.9621.00
62_E67_K0.9601.00
74_T91_Y0.9511.00
47_A90_T0.9421.00
46_V87_V0.9331.00
82_N112_R0.9221.00
79_K116_D0.9201.00
61_V71_I0.9201.00
68_V71_I0.9171.00
79_K118_K0.9011.00
80_D83_D0.8701.00
20_G60_I0.8611.00
58_K94_F0.8501.00
34_P49_Q0.8451.00
97_E102_F0.8301.00
90_T94_F0.8211.00
89_A93_A0.8191.00
59_A62_E0.8191.00
54_L94_F0.8171.00
46_V83_D0.8131.00
84_F107_C0.8101.00
32_Q60_I0.8061.00
44_A48_A0.7981.00
47_A51_R0.7981.00
44_A49_Q0.7971.00
54_L68_V0.7801.00
45_D118_K0.7771.00
74_T95_F0.7721.00
69_G96_T0.7571.00
54_L121_I0.7561.00
92_E102_F0.7501.00
79_K110_V0.7441.00
46_V119_I0.7401.00
29_T106_S0.7331.00
66_L126_V0.7271.00
71_I125_A0.7191.00
68_V94_F0.7181.00
37_P52_Q0.7151.00
79_K111_A0.7101.00
88_N91_Y0.7081.00
25_N126_V0.7011.00
46_V90_T0.7001.00
14_I115_K0.7001.00
50_A119_I0.6921.00
16_P88_N0.6891.00
45_D86_T0.6891.00
20_G64_A0.6810.99
47_A93_A0.6770.99
35_V40_G0.6760.99
20_G27_I0.6650.99
54_L91_Y0.6640.99
29_T57_V0.6620.99
77_F122_E0.6570.99
85_A89_A0.6550.99
75_T106_S0.6540.99
43_P49_Q0.6510.99
73_K106_S0.6490.99
48_A51_R0.6460.99
78_V81_L0.6400.99
81_L112_R0.6350.99
76_V121_I0.6340.99
23_L28_I0.6320.99
19_Q60_I0.6310.99
80_D118_K0.6270.99
53_S121_I0.6260.99
78_V83_D0.6160.99
9_N59_A0.6100.99
76_V105_R0.6090.99
84_F114_P0.5970.99
55_D59_A0.5960.99
27_I125_A0.5890.98
21_V72_V0.5800.98
18_V21_V0.5780.98
69_G97_E0.5770.98
61_V68_V0.5750.98
30_S104_A0.5700.98
23_L26_M0.5590.98
24_G126_V0.5580.98
37_P59_A0.5560.98
32_Q57_V0.5520.98
46_V86_T0.5500.98
79_K109_E0.5450.97
33_I115_K0.5440.97
9_N38_K0.5400.97
76_V119_I0.5390.97
71_I74_T0.5340.97
88_N92_E0.5320.97
42_V52_Q0.5250.97
17_Y31_G0.5250.97
26_M124_I0.5240.97
74_T121_I0.5230.97
32_Q56_N0.5210.97
84_F88_N0.5170.97
61_V123_A0.5150.96
75_T124_I0.5150.96
33_I53_S0.5140.96
83_D109_E0.5120.96
52_Q59_A0.5100.96
60_I63_A0.5080.96
112_R115_K0.5030.96
80_D109_E0.5030.96
53_S57_V0.5020.96
73_K104_A0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vczA 5 0.9609 100 0.127 Contact Map
2b33A 3 0.9688 100 0.134 Contact Map
1qu9A 3 0.9922 100 0.137 Contact Map
1xrgA 3 0.9688 100 0.137 Contact Map
2dyyA 3 0.9766 100 0.142 Contact Map
2cvlA 3 0.9688 100 0.146 Contact Map
1qd9A 3 0.9688 100 0.156 Contact Map
3k0tA 3 0.9688 100 0.159 Contact Map
1qahA 3 0.9766 100 0.159 Contact Map
1x25A 3 0.9766 100 0.159 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.006 seconds.