GREMLIN Database
YJFJ - Uncharacterized protein YjfJ
UniProt: P0AF78 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12485
Length: 232 (216)
Sequences: 1616 (1044)
Seq/√Len: 71.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_L87_P5.8691.00
78_L229_Q4.7801.00
70_K104_I3.1911.00
60_H64_K3.1001.00
108_E112_S3.0251.00
74_E78_L3.0191.00
91_N220_Q2.9701.00
63_L108_E2.8531.00
67_R108_E2.7671.00
145_T184_Q2.7601.00
33_Q37_D2.7301.00
221_D224_A2.6551.00
153_Q186_R2.4971.00
97_I222_V2.3741.00
2_G5_K2.3611.00
32_E139_M2.3451.00
138_Q177_Q2.3071.00
150_R154_A2.2941.00
46_G129_A2.2141.00
73_L76_R2.2001.00
63_L104_I2.1431.00
56_V115_E2.0881.00
78_L82_S2.0561.00
63_L67_R2.0411.00
39_K136_E2.0201.00
112_S116_V2.0181.00
87_P227_Q2.0121.00
67_R104_I1.9951.00
78_L226_L1.9521.00
72_S76_R1.9491.00
101_E105_T1.9331.00
134_Q138_Q1.9071.00
8_F12_K1.8741.00
224_A228_R1.8731.00
6_S23_E1.8481.00
225_R229_Q1.8351.00
49_R121_V1.7941.00
74_E225_R1.7761.00
74_E229_Q1.7511.00
105_T108_E1.7371.00
201_D204_E1.7291.00
70_K101_E1.7261.00
71_A75_A1.7201.00
182_E186_R1.7041.00
14_F29_R1.6781.00
33_Q36_R1.6681.00
225_R228_R1.6551.00
72_S75_A1.6380.99
220_Q224_A1.6060.99
116_V120_G1.5950.99
77_A226_L1.5580.99
67_R71_A1.5430.99
222_V225_R1.5400.99
32_E143_K1.5040.99
56_V118_R1.4940.99
149_Q187_L1.4820.99
56_V60_H1.4760.99
102_N105_T1.4150.98
20_E23_E1.4050.98
83_K86_N1.3700.98
89_L209_A1.3530.98
81_L226_L1.3460.98
98_A218_S1.3430.98
22_I29_R1.3260.98
91_N219_A1.3020.97
105_T109_Q1.2730.97
115_E119_D1.2440.96
87_P182_E1.2400.96
12_K37_D1.2360.96
63_L111_L1.2340.96
206_L210_G1.2270.96
58_L62_K1.2200.96
81_L227_Q1.2190.96
86_N205_K1.2080.96
37_D40_A1.1950.95
102_N218_S1.1860.95
13_S17_Q1.1800.95
142_V180_Q1.1710.95
20_E36_R1.1580.95
207_A210_G1.1510.94
97_I101_E1.1430.94
15_I18_A1.1230.94
153_Q187_L1.1120.93
64_K67_R1.0930.93
70_K97_I1.0880.93
64_K68_E1.0850.93
49_R125_V1.0770.92
88_S205_K1.0730.92
119_D123_K1.0670.92
124_A127_A1.0620.92
35_I132_I1.0620.92
60_H111_L1.0600.92
143_K147_A1.0490.91
114_L118_R1.0350.91
208_E212_G1.0330.91
202_L208_E1.0200.90
128_T135_F1.0060.89
63_L112_S1.0030.89
68_E72_S0.9980.89
75_A78_L0.9840.88
79_E83_K0.9810.88
66_L100_L0.9760.88
73_L96_E0.9550.87
146_E150_R0.9530.87
204_E207_A0.9370.86
131_R134_Q0.9360.86
17_Q29_R0.9340.86
37_D41_E0.9250.85
31_L173_L0.9170.84
92_E95_E0.9100.84
203_D206_L0.9060.84
153_Q157_T0.9060.84
30_M33_Q0.9040.84
15_I22_I0.9030.84
96_E99_R0.9010.83
169_A173_L0.9010.83
13_S21_S0.9000.83
221_D225_R0.8940.83
13_S30_M0.8910.83
189_A193_L0.8890.83
42_L132_I0.8850.82
81_L220_Q0.8770.82
9_T12_K0.8750.82
95_E99_R0.8720.81
130_Q134_Q0.8710.81
56_V111_L0.8650.81
77_A189_A0.8620.81
74_E97_I0.8580.80
66_L103_L0.8470.79
175_R178_T0.8440.79
9_T172_S0.8390.79
11_G18_A0.8320.78
41_E45_A0.8200.77
31_L139_M0.8180.77
3_I15_I0.8170.77
178_T182_E0.8140.77
109_Q224_A0.8110.76
60_H115_E0.8010.76
205_K208_E0.8010.76
40_A44_K0.8010.76
18_A22_I0.7950.75
109_Q112_S0.7840.74
69_R100_L0.7790.74
26_Q29_R0.7780.73
94_A97_I0.7780.73
57_K60_H0.7780.73
62_K65_D0.7770.73
126_T130_Q0.7750.73
65_D71_A0.7730.73
223_L227_Q0.7720.73
10_L31_L0.7720.73
17_Q21_S0.7690.73
132_I172_S0.7670.72
49_R52_L0.7660.72
16_S36_R0.7650.72
24_E29_R0.7650.72
205_K209_A0.7640.72
113_N117_S0.7550.71
48_S147_A0.7530.71
53_L122_E0.7530.71
24_E90_I0.7490.71
51_D69_R0.7450.70
144_A192_Q0.7440.70
157_T190_A0.7420.70
39_K132_I0.7410.70
9_T14_F0.7400.70
202_L206_L0.7400.70
59_S63_L0.7390.70
171_E207_A0.7380.69
77_A94_A0.7350.69
156_T159_T0.7260.68
57_K188_D0.7180.67
87_P91_N0.7140.67
31_L38_A0.7130.67
93_V206_L0.7130.67
206_L209_A0.7120.67
9_T139_M0.7090.66
19_E23_E0.7090.66
98_A219_A0.7070.66
54_A202_L0.7050.66
89_L205_K0.7010.65
121_V151_A0.6980.65
73_L206_L0.6980.65
34_H73_L0.6980.65
154_A157_T0.6970.65
157_T178_T0.6970.65
114_L117_S0.6940.65
42_L58_L0.6920.64
107_E110_V0.6910.64
202_L205_K0.6890.64
74_E81_L0.6860.64
226_L229_Q0.6820.63
65_D119_D0.6800.63
66_L104_I0.6780.63
160_V163_S0.6760.63
79_E191_A0.6760.63
61_D185_A0.6720.62
12_K33_Q0.6660.62
73_L93_V0.6660.62
183_R186_R0.6650.61
23_E30_M0.6630.61
74_E101_E0.6620.61
98_A222_V0.6620.61
41_E191_A0.6590.61
155_V176_L0.6560.60
133_A137_Q0.6530.60
140_E149_Q0.6510.60
6_S13_S0.6490.60
110_V114_L0.6470.59
42_L50_V0.6460.59
204_E221_D0.6410.59
26_Q147_A0.6390.58
9_T30_M0.6380.58
70_K106_A0.6370.58
9_T19_E0.6360.58
38_A135_F0.6340.58
117_S124_A0.6320.58
219_A229_Q0.6310.57
79_E82_S0.6290.57
74_E95_E0.6280.57
16_S152_Q0.6270.57
187_L190_A0.6240.57
42_L45_A0.6230.56
111_L115_E0.6210.56
102_N106_A0.6200.56
31_L176_L0.6200.56
101_E104_I0.6190.56
87_P94_A0.6180.56
143_K146_E0.6170.56
55_R140_E0.6160.56
66_L107_E0.6160.56
87_P90_I0.6140.55
208_E211_I0.6090.55
10_L17_Q0.6070.54
6_S25_T0.6050.54
65_D68_E0.6040.54
94_A128_T0.6020.54
11_G15_I0.5990.54
146_E176_L0.5970.53
10_L20_E0.5960.53
172_S176_L0.5950.53
99_R103_L0.5950.53
118_R122_E0.5940.53
84_N229_Q0.5900.52
127_A130_Q0.5880.52
117_S120_G0.5860.52
76_R93_V0.5810.51
76_R147_A0.5810.51
89_L202_L0.5790.51
2_G65_D0.5790.51
52_L114_L0.5770.51
15_I102_N0.5760.51
93_V131_R0.5760.51
58_L65_D0.5750.51
94_A98_A0.5730.50
50_V58_L0.5730.50
35_I39_K0.5720.50
173_L177_Q0.5720.50
65_D142_V0.5690.50
204_E208_E0.5680.50
153_Q191_A0.5670.50
52_L55_R0.5660.50
76_R79_E0.5640.49
32_E141_V0.5630.49
173_L183_R0.5610.49
130_Q164_S0.5590.49
8_F147_A0.5580.49
17_Q32_E0.5560.48
52_L172_S0.5540.48
8_F30_M0.5540.48
30_M180_Q0.5530.48
4_L153_Q0.5520.48
35_I136_E0.5510.48
212_G217_S0.5500.48
41_E156_T0.5490.47
49_R124_A0.5470.47
52_L148_M0.5460.47
25_T94_A0.5460.47
4_L217_S0.5400.46
20_E30_M0.5400.46
150_R224_A0.5390.46
92_E178_T0.5380.46
98_A102_N0.5380.46
95_E219_A0.5350.46
19_E22_I0.5350.46
26_Q131_R0.5330.45
219_A222_V0.5330.45
179_R182_E0.5320.45
5_K208_E0.5310.45
49_R53_L0.5300.45
92_E205_K0.5290.45
148_M151_A0.5270.45
53_L118_R0.5260.45
145_T149_Q0.5260.45
120_G124_A0.5260.45
48_S122_E0.5240.44
42_L129_A0.5230.44
113_N163_S0.5220.44
34_H176_L0.5220.44
26_Q38_A0.5210.44
6_S19_E0.5200.44
219_A228_R0.5200.44
26_Q32_E0.5200.44
34_H76_R0.5200.44
112_S115_E0.5200.44
96_E110_V0.5200.44
108_E212_G0.5190.44
122_E125_V0.5190.44
57_K61_D0.5170.44
69_R72_S0.5160.43
9_T132_I0.5150.43
32_E193_L0.5140.43
30_M34_H0.5110.43
76_R86_N0.5100.43
55_R59_S0.5090.43
115_E133_A0.5090.43
11_G131_R0.5080.42
9_T46_G0.5080.42
207_A211_I0.5070.42
68_E130_Q0.5050.42
21_S87_P0.5040.42
89_L174_K0.5020.42
12_K19_E0.5000.42
105_T208_E0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1i84S 2 0.4181 95.3 0.877 Contact Map
1c1gA 2 0.944 87.2 0.903 Contact Map
3ojaB 1 0.5474 82.7 0.908 Contact Map
2gd5A 2 0.6853 82.1 0.909 Contact Map
4abmA 2 0.3405 81.8 0.909 Contact Map
2dfsA 2 0.5345 74 0.915 Contact Map
3vkgA 2 0.8922 71.1 0.917 Contact Map
4cgkA 3 0.6379 67.8 0.919 Contact Map
3frtA 1 0.5991 64 0.921 Contact Map
4iloA 3 0.7155 63 0.922 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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