GREMLIN Database
MOTB - Motility protein B
UniProt: P0AF06 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10602
Length: 308 (254)
Sequences: 2761 (2209)
Seq/√Len: 138.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
162_R169_E5.4821.00
212_E223_R3.5361.00
197_D210_N3.4531.00
177_R224_E3.1851.00
30_Y34_M2.9451.00
208_Y216_D2.9281.00
119_R123_D2.8401.00
241_M245_M2.8361.00
40_F44_M2.7411.00
28_I31_A2.7291.00
192_L222_R2.6021.00
176_L224_E2.6001.00
209_S212_E2.5281.00
248_S256_V2.4991.00
51_S54_E2.4021.00
29_A33_F2.4011.00
151_Q261_S2.3101.00
50_S55_L2.3021.00
117_K121_D2.2731.00
250_R254_D2.2621.00
249_D252_P2.2481.00
29_A38_M2.2271.00
163_T199_F2.1941.00
199_F254_D2.1901.00
40_F43_V2.1631.00
195_H245_M2.1591.00
168_V224_E2.1471.00
214_S240_G2.1171.00
203_S208_Y2.1131.00
232_S244_T2.0131.00
166_A216_D1.9591.00
30_Y35_T1.9121.00
215_A240_G1.8571.00
222_R238_V1.8511.00
154_D158_R1.8051.00
38_M42_L1.7431.00
25_S29_A1.7261.00
215_A219_N1.7041.00
166_A207_G1.6931.00
24_G27_K1.6781.00
219_N222_R1.6711.00
52_P56_I1.6581.00
183_L230_L1.6451.00
198_D254_D1.5691.00
89_D92_Q1.5611.00
14_R19_H1.5591.00
24_G29_A1.5471.00
208_Y212_E1.5431.00
248_S254_D1.5301.00
72_G76_I1.4971.00
34_M40_F1.4911.00
72_G77_S1.4781.00
73_G77_S1.4781.00
201_Y207_G1.4691.00
22_A25_S1.4611.00
72_G75_R1.4321.00
170_P173_R1.4141.00
207_G216_D1.4001.00
176_L221_S1.3991.00
168_V172_M1.3811.00
106_L109_R1.3561.00
116_R120_G1.3471.00
106_L110_M1.3461.00
188_N234_K1.3301.00
180_A225_L1.3281.00
201_Y204_G1.3051.00
22_A29_A1.3041.00
226_M232_S1.2871.00
24_G43_V1.2851.00
72_G78_N1.2801.00
76_I80_E1.2781.00
193_S263_L1.2571.00
198_D250_R1.2551.00
163_T197_D1.2511.00
191_S239_V1.2321.00
92_Q95_G1.2321.00
193_S239_V1.2271.00
223_R227_V1.2151.00
232_S243_A1.2131.00
198_D252_P1.2111.00
179_I183_L1.1891.00
73_G76_I1.1630.99
115_L118_L1.1600.99
183_L264_V1.1480.99
110_M114_R1.1410.99
17_K20_G1.1380.99
248_S251_G1.1300.99
30_Y44_M1.1270.99
164_G210_N1.1230.99
210_N258_R1.1210.99
111_E115_L1.1180.99
29_A40_F1.1180.99
193_S241_M1.1170.99
224_E227_V1.1140.99
50_S54_E1.1120.99
201_Y209_S1.1100.99
112_Q116_R1.1080.99
29_A46_L1.1040.99
177_R228_G1.1040.99
20_G23_H1.1030.99
49_I52_P1.1010.99
28_I33_F1.1010.99
200_P210_N1.0980.99
177_R181_P1.0920.99
21_A24_G1.0920.99
91_T96_E1.0850.99
116_R119_R1.0700.99
86_G89_D1.0580.99
209_S223_R1.0500.99
29_A36_A1.0440.99
75_R78_N1.0440.99
216_D219_N1.0420.99
224_E228_G1.0400.99
173_R224_E1.0400.99
197_D258_R1.0380.99
149_R261_S1.0370.99
164_G197_D1.0370.99
72_G81_S1.0330.99
23_H28_I1.0320.99
25_S38_M1.0290.99
27_K36_A1.0280.99
201_Y208_Y1.0240.99
113_S116_R1.0210.99
20_G24_G1.0170.99
33_F38_M1.0140.99
13_R16_A1.0120.98
33_F39_A1.0100.98
39_A45_W1.0060.98
28_I39_A0.9940.98
42_L46_L0.9910.98
13_R18_S0.9870.98
118_L123_D0.9730.98
208_Y223_R0.9710.98
72_G83_I0.9690.98
39_A43_V0.9640.98
93_S96_E0.9560.98
22_A27_K0.9560.98
203_S209_S0.9550.98
120_G123_D0.9540.98
146_E193_S0.9530.98
49_I53_K0.9510.98
160_M193_S0.9460.98
62_F65_P0.9440.98
109_R112_Q0.9430.98
142_D151_Q0.9400.98
142_D149_R0.9380.98
174_D177_R0.9380.98
93_S97_V0.9340.97
90_Y95_G0.9310.97
24_G46_L0.9190.97
72_G80_E0.9110.97
195_H242_A0.9070.97
84_P87_G0.9020.97
144_V147_G0.8960.97
211_W238_V0.8910.97
69_A73_G0.8900.97
146_E149_R0.8850.96
68_T72_G0.8850.96
147_G265_L0.8850.96
100_Q103_I0.8770.96
221_S260_I0.8720.96
91_T94_Q0.8710.96
36_A42_L0.8680.96
120_G124_Q0.8540.96
74_D80_E0.8540.96
141_I148_L0.8540.96
26_W39_A0.8540.96
86_G93_S0.8530.96
29_A39_A0.8510.96
37_M46_L0.8510.96
163_T210_N0.8470.95
180_A230_L0.8460.95
25_S34_M0.8430.95
58_I62_F0.8430.95
176_L225_L0.8420.95
77_S80_E0.8420.95
96_E99_K0.8400.95
147_G188_N0.8380.95
76_I79_S0.8320.95
57_Q60_E0.8280.95
46_L61_Y0.8250.95
52_P55_L0.8250.95
149_R263_L0.8240.95
211_W242_A0.8220.95
102_N105_E0.8220.95
24_G28_I0.8210.95
140_K153_I0.8200.95
195_H246_R0.8170.95
25_S43_V0.8100.94
195_H260_I0.8090.94
24_G40_F0.8090.94
121_D185_G0.8050.94
171_Y174_D0.8040.94
215_A238_V0.7990.94
60_E64_T0.7940.94
87_G95_G0.7930.94
118_L125_L0.7930.94
203_S206_K0.7920.94
212_E219_N0.7910.94
59_A62_F0.7910.94
42_L45_W0.7850.93
32_D41_F0.7810.93
43_V46_L0.7810.93
90_Y94_Q0.7790.93
168_V221_S0.7720.93
56_I60_E0.7710.93
36_A46_L0.7650.92
78_N81_S0.7640.92
71_T74_D0.7640.92
191_S237_R0.7630.92
72_G82_P0.7620.92
102_N107_K0.7570.92
15_K18_S0.7570.92
73_G79_S0.7570.92
125_L128_S0.7550.92
29_A43_V0.7530.92
77_S82_P0.7510.92
30_Y39_A0.7500.92
90_Y93_S0.7490.92
84_P95_G0.7470.91
152_I176_L0.7390.91
220_A223_R0.7360.91
203_S207_G0.7330.91
248_S252_P0.7310.91
29_A55_L0.7270.90
95_G99_K0.7240.90
29_A42_L0.7220.90
94_Q98_N0.7200.90
103_I106_L0.7200.90
91_T95_G0.7200.90
86_G91_T0.7190.90
152_I160_M0.7120.89
92_Q96_E0.7100.89
231_D234_K0.7090.89
230_L236_L0.7080.89
184_N229_G0.7060.89
16_A19_H0.7040.89
162_R165_S0.7040.89
198_D253_D0.7030.89
77_S81_S0.7010.89
163_T201_Y0.7010.89
195_H265_L0.7010.89
24_G45_W0.7010.89
165_S206_K0.7000.89
53_K56_I0.6990.89
16_A20_G0.6990.89
68_T71_T0.6980.88
100_Q110_M0.6970.88
29_A34_M0.6960.88
152_I193_S0.6960.88
124_Q130_P0.6960.88
73_G78_N0.6960.88
14_R17_K0.6940.88
25_S33_F0.6890.88
100_Q104_E0.6830.87
27_K46_L0.6790.87
21_A25_S0.6780.87
75_R80_E0.6770.87
28_I43_V0.6740.87
84_P90_Y0.6710.86
154_D160_M0.6710.86
172_M193_S0.6710.86
74_D79_S0.6640.86
193_S261_S0.6640.86
124_Q128_S0.6640.86
164_G200_P0.6620.86
86_G90_Y0.6620.86
24_G30_Y0.6580.85
117_K120_G0.6550.85
87_G94_Q0.6540.85
80_E84_P0.6500.85
197_D254_D0.6500.85
89_D96_E0.6490.85
84_P89_D0.6460.84
151_Q188_N0.6450.84
85_G89_D0.6400.84
103_I114_R0.6400.84
69_A80_E0.6350.83
219_N238_V0.6350.83
115_L148_L0.6350.83
19_H24_G0.6330.83
88_D91_T0.6320.83
146_E263_L0.6320.83
109_R113_S0.6310.83
29_A61_Y0.6280.83
200_P209_S0.6280.83
219_N223_R0.6280.83
226_M236_L0.6270.82
53_K57_Q0.6250.82
101_P104_E0.6230.82
103_I107_K0.6230.82
129_D132_L0.6220.82
139_L226_M0.6210.82
85_G88_D0.6200.82
115_L121_D0.6200.82
192_L219_N0.6180.82
67_A70_V0.6170.81
198_D243_A0.6150.81
107_K110_M0.6120.81
162_R168_V0.6120.81
119_R143_L0.6120.81
78_N84_P0.6100.81
210_N214_S0.6100.81
59_A63_R0.6100.81
41_F45_W0.6090.81
139_L175_I0.6090.81
75_R79_S0.6090.81
108_K112_Q0.6060.80
184_N228_G0.6010.80
29_A45_W0.6000.80
85_G90_Y0.5990.80
123_D127_E0.5970.79
24_G36_A0.5960.79
108_K111_E0.5960.79
27_K35_T0.5920.79
50_S58_I0.5880.78
40_F46_L0.5870.78
267_K270_E0.5840.78
68_T73_G0.5840.78
162_R167_D0.5830.78
178_A181_P0.5810.77
36_A45_W0.5800.77
67_A71_T0.5790.77
225_L230_L0.5770.77
196_T258_R0.5730.77
22_A40_F0.5730.77
86_G96_E0.5710.76
22_A45_W0.5700.76
55_L58_I0.5690.76
158_R255_A0.5670.76
195_H261_S0.5660.76
102_N106_L0.5660.76
83_I87_G0.5650.76
34_M48_S0.5650.76
197_D201_Y0.5650.76
87_G90_Y0.5640.75
141_I261_S0.5620.75
216_D220_A0.5610.75
126_I129_D0.5600.75
125_L133_R0.5560.74
237_R265_L0.5540.74
27_K38_M0.5530.74
87_G92_Q0.5520.74
73_G82_P0.5510.74
181_P184_N0.5510.74
89_D95_G0.5500.74
69_A77_S0.5490.73
26_W41_F0.5490.73
47_I58_I0.5480.73
110_M113_S0.5470.73
33_F37_M0.5460.73
33_F47_I0.5450.73
67_A77_S0.5400.72
35_T211_W0.5400.72
218_A240_G0.5390.72
176_L227_V0.5370.72
25_S30_Y0.5370.72
25_S39_A0.5360.72
33_F45_W0.5340.71
34_M38_M0.5330.71
121_D124_Q0.5320.71
137_P140_K0.5320.71
34_M39_A0.5320.71
246_R252_P0.5280.71
204_G208_Y0.5250.70
162_R176_L0.5230.70
104_E118_L0.5200.69
89_D97_V0.5170.69
74_D82_P0.5170.69
168_V260_I0.5170.69
50_S60_E0.5140.69
152_I265_L0.5120.68
87_G91_T0.5110.68
146_E150_I0.5100.68
70_V73_G0.5090.68
18_S23_H0.5070.67
85_G92_Q0.5030.67
101_P105_E0.5000.66
191_S263_L0.5000.66
88_D99_K0.5000.66
198_D246_R0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zovA 2 0.539 100 0.542 Contact Map
2zvyA 2 0.5942 100 0.546 Contact Map
3wpwA 2 0.474 100 0.558 Contact Map
3s0yA 4 0.5974 100 0.572 Contact Map
3khnA 2 0.5162 100 0.587 Contact Map
4b62A 1 0.4578 100 0.6 Contact Map
3s06A 3 0.5097 100 0.61 Contact Map
2k1sA 1 0.474 100 0.618 Contact Map
3ldtA 2 0.4578 100 0.621 Contact Map
3oonA 2 0.3604 100 0.636 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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