GREMLIN Database
GYRA - DNA gyrase subunit A
UniProt: P0AES4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10423
Length: 875 (783)
Sequences: 5021 (2422)
Seq/√Len: 86.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
74_I85_V5.9561.00
374_R489_L5.6561.00
188_T514_G4.7341.00
199_D503_R4.5831.00
196_A203_I4.2571.00
192_N510_R4.2111.00
698_S724_I4.0401.00
392_P413_N3.7201.00
63_Y104_D3.5511.00
196_A211_H3.5451.00
141_E371_R3.4861.00
490_R497_R3.4701.00
490_R494_S3.3091.00
193_G212_I3.2561.00
246_A321_Y3.1631.00
112_I301_M3.1531.00
487_E497_R3.1381.00
197_Y351_I3.1081.00
651_A681_E3.0861.00
146_V157_D3.0251.00
197_Y203_I3.0151.00
699_A731_K2.8861.00
371_R375_D2.8731.00
487_E490_R2.8661.00
59_W132_H2.7611.00
395_E399_H2.7591.00
144_D364_R2.7521.00
195_L507_E2.7481.00
204_S207_G2.7451.00
188_T516_K2.7041.00
385_V450_L2.7011.00
699_A730_D2.6531.00
206_E234_R2.6471.00
693_E705_R2.6391.00
69_V125_I2.5991.00
68_R76_K2.5971.00
163_I168_V2.5971.00
208_L347_L2.5951.00
677_V719_T2.5921.00
363_T367_I2.5601.00
205_I346_N2.5381.00
191_I506_L2.4851.00
198_I499_M2.4701.00
456_Q460_D2.4501.00
508_L512_Q2.4361.00
188_T192_N2.4121.00
545_H577_F2.4081.00
133_E513_F2.3741.00
375_D453_Q2.3711.00
247_E262_H2.3641.00
188_T510_R2.3531.00
208_L348_K2.3511.00
100_Y515_D2.3501.00
727_G769_K2.3451.00
257_E313_G2.3031.00
196_A200_D2.3001.00
704_V768_T2.3001.00
203_I207_G2.2721.00
722_R725_R2.2701.00
246_A259_I2.2651.00
182_I334_M2.2621.00
484_Q488_L2.2541.00
140_K369_E2.2441.00
689_S692_D2.2301.00
290_S308_K2.2261.00
245_R520_E2.2241.00
595_S681_E2.2061.00
380_L474_L2.1641.00
704_V764_K2.1611.00
497_R500_E2.1541.00
104_D126_R2.1521.00
338_H345_M2.1501.00
714_M718_T2.1461.00
200_D207_G2.1351.00
690_G708_E2.1331.00
651_A731_K2.1321.00
261_V305_I2.1311.00
129_K512_Q2.1301.00
147_D154_K2.1241.00
651_A680_D2.1031.00
649_A696_L2.0941.00
480_E484_Q2.0931.00
710_S765_S2.0891.00
500_E504_E2.0861.00
376_R477_E2.0811.00
489_L493_G2.0731.00
66_S89_I2.0721.00
649_A735_L2.0711.00
372_K375_D2.0681.00
539_V604_V2.0621.00
359_R499_M2.0581.00
168_V190_V2.0571.00
724_I732_V2.0401.00
396_L409_A2.0211.00
147_D151_G2.0131.00
366_T488_L1.9941.00
190_V212_I1.9901.00
246_A317_L1.9841.00
596_R628_D1.9801.00
584_A588_D1.9731.00
359_R495_A1.9641.00
476_D480_E1.9631.00
696_L723_G1.9551.00
206_E230_E1.9521.00
408_T412_A1.9461.00
244_A261_V1.9451.00
761_Y773_S1.9441.00
536_Q585_N1.9331.00
230_E234_R1.9271.00
362_V502_I1.9081.00
363_T492_L1.8871.00
37_V353_A1.8851.00
748_T774_I1.8761.00
195_L503_R1.8761.00
353_A356_R1.8741.00
264_I303_I1.8731.00
346_N349_D1.8691.00
407_K456_Q1.8681.00
205_I234_R1.8671.00
83_S87_D1.8651.00
241_Y327_Q1.8601.00
272_R275_E1.8591.00
48_V88_T1.8591.00
348_K352_A1.8581.00
472_E476_D1.8511.00
491_I501_V1.8471.00
203_I211_H1.8401.00
197_Y352_A1.8331.00
655_V723_G1.8321.00
688_T708_E1.8271.00
402_T405_E1.8251.00
182_I350_I1.8211.00
494_S497_R1.8181.00
343_K349_D1.8111.00
84_A88_T1.8091.00
479_K483_D1.7991.00
498_L501_V1.7771.00
764_K768_T1.7731.00
594_S631_I1.7671.00
734_S786_A1.7631.00
205_I348_K1.7501.00
377_A478_Y1.7491.00
163_I509_V1.7371.00
194_C355_V1.7351.00
385_V389_N1.7051.00
64_K68_R1.6991.00
823_I826_R1.6971.00
197_Y355_V1.6941.00
68_R72_D1.6871.00
697_F786_A1.6841.00
475_L479_K1.6811.00
647_F694_V1.6801.00
369_E488_L1.6741.00
214_G229_I1.6721.00
367_I371_R1.6711.00
404_A408_T1.6691.00
207_G210_E1.6671.00
89_I125_I1.6371.00
696_L732_V1.6291.00
647_F655_V1.6231.00
399_H409_A1.6221.00
352_A356_R1.6191.00
144_D157_D1.6171.00
133_E136_A1.6101.00
37_V350_I1.6011.00
338_H353_A1.5991.00
654_T722_R1.5871.00
808_R811_E1.5791.00
487_E491_I1.5591.00
693_E707_K1.5581.00
470_E473_K1.5431.00
226_R523_A1.5401.00
403_P464_Q1.5351.00
334_M350_I1.5251.00
90_V117_A1.5181.00
393_I410_L1.5131.00
365_R505_E1.5051.00
200_D203_I1.5021.00
484_Q487_E1.5011.00
68_R153_E1.4940.99
762_P771_V1.4920.99
752_Y823_I1.4900.99
241_Y329_S1.4890.99
339_H356_R1.4870.99
245_R263_E1.4800.99
585_N588_D1.4750.99
363_T498_L1.4720.99
700_E782_L1.4570.99
66_S125_I1.4490.99
51_A72_D1.4420.99
92_M98_L1.4410.99
645_K713_A1.4390.99
595_S630_R1.4390.99
486_A490_R1.4320.99
252_A258_T1.4300.99
135_M159_M1.4270.99
172_S181_N1.4250.99
649_A732_V1.4180.99
194_C351_I1.4070.99
295_E304_V1.4030.99
515_D518_R1.3990.99
384_A478_Y1.3970.99
68_R75_G1.3910.99
537_E586_T1.3860.99
277_I292_L1.3850.99
51_A74_I1.3840.99
495_A499_M1.3790.99
478_Y482_L1.3730.99
227_R231_E1.3660.99
231_E234_R1.3660.99
546_Q573_K1.3610.99
545_H579_D1.3610.99
68_R120_M1.3590.99
276_K279_E1.3540.99
777_T820_Q1.3540.99
596_R626_E1.3450.99
396_L413_N1.3440.99
248_V259_I1.3440.99
595_S629_E1.3440.99
277_I305_I1.3430.99
325_Q328_V1.3420.99
764_K771_V1.3360.99
274_I303_I1.3310.99
141_E367_I1.3270.99
483_D487_E1.3250.99
381_E482_L1.3210.99
76_K153_E1.3160.99
233_Y332_I1.3140.99
647_F711_V1.3120.99
504_E508_L1.3100.99
389_N450_L1.3020.99
256_R290_S1.2950.99
181_N331_G1.2930.99
99_R515_D1.2910.99
480_E483_D1.2900.99
807_T824_L1.2880.98
401_P405_E1.2880.98
646_V685_V1.2850.98
490_R493_G1.2840.98
743_A755_R1.2830.98
311_A316_V1.2820.98
503_R507_E1.2690.98
411_V455_A1.2680.98
507_E510_R1.2680.98
381_E478_Y1.2670.98
205_I208_L1.2660.98
295_E302_R1.2620.98
746_T773_S1.2600.98
392_P395_E1.2530.98
233_Y347_L1.2520.98
293_R306_E1.2500.98
593_F685_V1.2460.98
251_D257_E1.2460.98
507_E511_E1.2460.98
349_D352_A1.2450.98
273_L303_I1.2430.98
359_R498_L1.2360.98
239_K329_S1.2330.98
657_K713_A1.2310.98
249_E302_R1.2260.98
773_S783_V1.2180.98
205_I209_M1.2170.98
459_L464_Q1.2150.98
62_A126_R1.2140.98
675_K718_T1.2130.98
648_M682_L1.2100.98
491_I497_R1.2100.98
289_I305_I1.2080.98
274_I292_L1.2070.98
486_A489_L1.2060.98
591_L599_V1.2040.98
693_E763_T1.2040.98
72_D76_K1.2020.98
405_E409_A1.2020.98
384_A475_L1.2000.98
50_Y53_N1.1980.98
756_T761_Y1.1960.98
12_N15_E1.1950.98
197_Y348_K1.1920.97
356_R359_R1.1890.97
645_K657_K1.1790.97
258_T306_E1.1760.97
698_S730_D1.1750.97
743_A814_I1.1700.97
652_N679_G1.1690.97
14_E18_K1.1680.97
483_D486_A1.1660.97
30_V337_L1.1660.97
222_I245_R1.1660.97
379_I457_A1.1630.97
725_R769_K1.1570.97
601_S666_L1.1550.97
196_A207_G1.1530.97
567_K612_R1.1520.97
792_C810_S1.1480.97
21_Y31_G1.1460.97
610_A614_A1.1430.97
191_I510_R1.1430.97
362_V505_E1.1430.97
772_I775_K1.1420.97
246_A261_V1.1400.97
383_L474_L1.1400.97
242_I519_T1.1370.97
55_L72_D1.1340.97
642_E661_T1.1340.97
49_L135_M1.1340.97
74_I149_Y1.1260.96
378_H451_T1.1260.96
409_A412_A1.1170.96
504_E507_E1.1170.96
335_V344_I1.1160.96
229_I240_V1.1130.96
244_A326_L1.1110.96
362_V498_L1.1110.96
407_K452_E1.1100.96
411_V452_E1.1080.96
354_F358_R1.1060.96
19_S23_D1.1050.96
774_I780_N1.1040.96
799_T825_I1.1040.96
536_Q586_T1.1030.96
64_K152_T1.1020.96
598_R626_E1.1010.96
367_I374_R1.1000.96
249_E260_I1.0990.96
380_L481_L1.0980.96
248_V317_L1.0980.96
51_A85_V1.0950.96
59_W129_K1.0890.96
336_A350_I1.0860.96
659_V713_A1.0860.96
242_I328_V1.0820.96
214_G521_I1.0810.96
654_T719_T1.0810.96
240_V332_I1.0790.95
649_A723_G1.0780.95
221_A244_A1.0750.95
384_A474_L1.0750.95
232_A332_I1.0700.95
749_Q782_L1.0690.95
184_P218_P1.0640.95
647_F688_T1.0630.95
139_E369_E1.0610.95
37_V345_M1.0560.95
695_M703_V1.0540.95
307_V311_A1.0540.95
471_H475_L1.0520.95
572_I578_I1.0510.95
74_I83_S1.0500.95
584_A604_V1.0480.95
222_I242_I1.0480.95
658_T663_F1.0460.95
183_P334_M1.0450.95
496_D504_E1.0440.95
776_V780_N1.0440.95
700_E730_D1.0430.95
390_I398_R1.0400.94
366_T491_I1.0390.94
45_H97_S1.0370.94
377_A485_I1.0340.94
222_I522_T1.0330.94
772_I818_N1.0320.94
659_V662_E1.0320.94
406_A467_T1.0290.94
168_V187_L1.0290.94
413_N448_Y1.0290.94
162_K358_R1.0270.94
338_H343_K1.0260.94
747_A824_L1.0250.94
648_M673_A1.0250.94
611_T614_A1.0200.94
163_I191_I1.0150.94
695_M744_I1.0140.94
756_T760_E1.0090.94
686_D735_L1.0070.93
815_V819_T1.0070.93
652_N680_D1.0050.93
191_I194_C1.0030.93
209_M234_R1.0020.93
192_N195_L1.0020.93
73_V85_V1.0020.93
368_F372_K0.9960.93
58_D61_K0.9920.93
134_L161_T0.9910.93
103_V125_I0.9910.93
658_T662_E0.9910.93
654_T677_V0.9910.93
251_D255_G0.9890.93
593_F599_V0.9890.93
663_F673_A0.9880.93
192_N507_E0.9880.93
803_T828_A0.9880.93
212_I347_L0.9850.93
194_C506_L0.9830.93
276_K325_Q0.9830.93
220_A245_R0.9820.93
307_V316_V0.9780.92
226_R229_I0.9720.92
141_E364_R0.9680.92
228_G231_E0.9660.92
586_T604_V0.9650.92
479_K482_L0.9590.92
684_G735_L0.9580.92
648_M685_V0.9580.92
531_E603_K0.9570.92
393_I448_Y0.9560.92
389_N392_P0.9550.92
371_R374_R0.9550.92
541_V604_V0.9540.92
376_R380_L0.9520.91
55_L68_R0.9490.91
130_I165_N0.9460.91
385_V449_Y0.9450.91
487_E494_S0.9440.91
675_K717_N0.9430.91
195_L510_R0.9430.91
200_D204_S0.9430.91
396_L455_A0.9410.91
261_V326_L0.9400.91
739_R742_G0.9400.91
102_L134_L0.9390.91
725_R767_A0.9390.91
166_L336_A0.9370.91
493_G497_R0.9350.91
60_N132_H0.9330.91
776_V779_R0.9320.91
400_A409_A0.9320.91
508_L511_E0.9310.90
596_R629_E0.9300.90
592_C634_I0.9290.90
351_I355_V0.9230.90
297_D301_M0.9200.90
100_Y130_I0.9190.90
698_S732_V0.9170.90
64_K76_K0.9160.90
396_L448_Y0.9160.90
55_L69_V0.9130.90
377_A482_L0.9120.90
199_D507_E0.9080.89
497_R501_V0.9050.89
370_L485_I0.9040.89
72_D149_Y0.9020.89
496_D500_E0.9000.89
619_I631_I0.8980.89
57_N69_V0.8970.89
203_I355_V0.8970.89
196_A210_E0.8950.89
297_D300_G0.8920.89
543_L634_I0.8910.88
188_T511_E0.8910.88
136_A358_R0.8910.88
192_N514_G0.8890.88
226_R230_E0.8870.88
457_A461_L0.8860.88
487_E501_V0.8850.88
789_V809_V0.8850.88
225_G228_G0.8850.88
714_M719_T0.8840.88
452_E456_Q0.8830.88
387_L471_H0.8810.88
539_V586_T0.8800.88
702_K769_K0.8800.88
113_D270_K0.8760.88
663_F714_M0.8740.87
491_I498_L0.8640.87
198_I503_R0.8620.87
200_D211_H0.8600.87
630_R681_E0.8600.87
51_A77_Y0.8590.87
509_V513_F0.8590.87
212_I346_N0.8580.87
538_D585_N0.8580.87
268_V273_L0.8570.86
141_E375_D0.8570.86
127_L131_A0.8550.86
381_E451_T0.8530.86
187_L509_V0.8520.86
780_N820_Q0.8500.86
162_K509_V0.8460.86
660_L687_L0.8460.86
70_V120_M0.8450.86
692_D739_R0.8450.86
243_R327_Q0.8430.86
487_E504_E0.8420.85
26_M30_V0.8420.85
746_T761_Y0.8420.85
251_D254_T0.8420.85
192_N213_P0.8410.85
462_R465_K0.8400.85
51_A55_L0.8390.85
16_E20_S0.8380.85
274_I278_A0.8370.85
50_Y54_V0.8370.85
130_I163_I0.8370.85
644_V687_L0.8360.85
102_L165_N0.8360.85
360_E367_I0.8360.85
100_Y516_K0.8350.85
227_R230_E0.8340.85
58_D132_H0.8340.85
377_A381_E0.8330.85
366_T492_L0.8300.85
696_L724_I0.8290.85
588_D638_T0.8290.85
100_Y514_G0.8270.84
476_D479_K0.8250.84
482_L486_A0.8240.84
667_R671_K0.8200.84
650_T674_I0.8200.84
63_Y106_Q0.8190.84
317_L321_Y0.8190.84
726_L730_D0.8180.84
253_K258_T0.8150.84
162_K508_L0.8120.83
279_E283_E0.8090.83
584_A636_P0.8080.83
31_G171_S0.8050.83
259_I317_L0.8040.83
197_Y201_E0.8030.83
500_E511_E0.8020.83
625_L631_I0.8010.83
55_L149_Y0.8010.83
682_L685_V0.8010.83
807_T811_E0.7990.82
333_N344_I0.7970.82
710_S764_K0.7960.82
366_T501_V0.7950.82
404_A407_K0.7920.82
246_A313_G0.7920.82
168_V191_I0.7920.82
674_I682_L0.7920.82
645_K690_G0.7910.82
260_I304_V0.7910.82
69_V75_G0.7900.82
761_Y819_T0.7900.82
774_I783_V0.7890.82
137_D140_K0.7890.82
55_L76_K0.7880.81
345_M353_A0.7870.81
543_L582_L0.7870.81
647_F723_G0.7860.81
652_N731_K0.7860.81
194_C354_F0.7860.81
706_F711_V0.7830.81
744_I758_V0.7820.81
541_V607_L0.7810.81
809_V812_I0.7810.81
393_I450_L0.7800.81
387_L474_L0.7790.81
205_I211_H0.7790.81
275_E279_E0.7790.81
649_A655_V0.7790.81
222_I520_E0.7780.81
62_A152_T0.7780.81
204_S348_K0.7780.81
190_V193_G0.7770.81
166_L350_I0.7770.81
461_L465_K0.7750.80
69_V74_I0.7750.80
56_G61_K0.7750.80
205_I347_L0.7740.80
64_K153_E0.7740.80
582_L634_I0.7730.80
191_I509_V0.7720.80
149_Y152_T0.7720.80
745_L812_I0.7720.80
697_F773_S0.7710.80
366_T484_Q0.7710.80
213_P226_R0.7710.80
686_D737_V0.7700.80
392_P448_Y0.7700.80
389_N413_N0.7700.80
193_G208_L0.7690.80
38_R158_V0.7690.80
343_K353_A0.7670.80
148_N152_T0.7660.80
649_A684_G0.7660.80
186_N514_G0.7650.80
195_L199_D0.7640.79
223_I240_V0.7630.79
130_I187_L0.7630.79
637_V660_L0.7630.79
644_V689_S0.7620.79
70_V82_D0.7620.79
225_G229_I0.7610.79
369_E484_Q0.7610.79
239_K331_G0.7610.79
738_P758_V0.7600.79
395_E398_R0.7590.79
270_K294_D0.7590.79
589_H601_S0.7590.79
541_V582_L0.7580.79
136_A162_K0.7570.79
505_E508_L0.7570.79
192_N211_H0.7570.79
702_K727_G0.7560.79
382_A450_L0.7560.79
211_H348_K0.7560.79
389_N396_L0.7550.79
402_T408_T0.7550.79
594_S600_Y0.7540.79
137_D142_T0.7540.79
388_A471_H0.7540.79
99_R518_R0.7530.78
543_L580_R0.7530.78
647_F735_L0.7510.78
549_V619_I0.7510.78
194_C502_I0.7500.78
120_M153_E0.7490.78
646_V660_L0.7490.78
494_S500_E0.7480.78
383_L469_L0.7470.78
406_A459_L0.7460.78
643_G661_T0.7460.78
473_K476_D0.7460.78
794_Q808_R0.7450.78
490_R498_L0.7440.78
536_Q587_H0.7440.78
699_A733_V0.7420.77
396_L464_Q0.7410.77
234_R348_K0.7410.77
382_A451_T0.7400.77
98_L101_M0.7400.77
244_A321_Y0.7390.77
675_K719_T0.7390.77
774_I779_R0.7390.77
101_M128_A0.7370.77
364_R367_I0.7360.77
757_A814_I0.7350.77
383_L461_L0.7350.77
736_I788_Q0.7350.77
794_Q806_R0.7340.77
702_K764_K0.7340.77
72_D75_G0.7310.76
252_A255_G0.7300.76
192_N511_E0.7270.76
272_R276_K0.7270.76
315_V532_D0.7270.76
510_R514_G0.7260.76
762_P765_S0.7250.76
378_H453_Q0.7250.76
74_I88_T0.7250.76
594_S629_E0.7240.76
187_L191_I0.7230.76
386_A390_I0.7230.76
199_D496_D0.7210.75
240_V329_S0.7210.75
490_R495_A0.7200.75
165_N168_V0.7190.75
539_V551_Y0.7180.75
540_V554_L0.7180.75
130_I133_E0.7180.75
128_A131_A0.7180.75
339_H343_K0.7180.75
551_Y609_E0.7160.75
106_Q617_R0.7160.75
239_K242_I0.7160.75
588_D636_P0.7150.75
114_G269_N0.7150.75
650_T680_D0.7150.75
748_T783_V0.7140.75
229_I232_A0.7140.75
57_N74_I0.7140.75
707_K763_T0.7120.74
401_P468_G0.7120.74
292_L305_I0.7110.74
112_I264_I0.7100.74
66_S74_I0.7100.74
403_P456_Q0.7090.74
397_I463_L0.7080.74
383_L386_A0.7070.74
244_A264_I0.7060.74
807_T812_I0.7060.74
791_D810_S0.7060.74
487_E500_E0.7050.74
57_N64_K0.7050.74
755_R814_I0.7050.74
633_A685_V0.7050.74
391_D398_R0.7040.74
257_E307_V0.7040.74
209_M348_K0.7030.74
569_A804_L0.7020.73
87_D91_R0.7010.73
278_A292_L0.7010.73
657_K708_E0.7010.73
75_G153_E0.7010.73
765_S768_T0.7010.73
699_A782_L0.7000.73
600_Y670_G0.7000.73
286_V319_N0.6990.73
548_Y618_P0.6990.73
639_E642_E0.6980.73
148_N153_E0.6980.73
285_R323_Q0.6960.73
386_A393_I0.6940.73
797_M824_L0.6940.73
595_S632_T0.6930.72
256_R308_K0.6920.72
248_V307_V0.6920.72
158_V357_H0.6900.72
540_V583_V0.6900.72
578_I581_L0.6890.72
779_R820_Q0.6880.72
741_D759_A0.6880.72
261_V303_I0.6880.72
459_L465_K0.6870.72
757_A760_E0.6870.72
332_I350_I0.6860.72
66_S120_M0.6850.72
380_L478_Y0.6840.72
592_C623_L0.6830.71
345_M349_D0.6820.71
223_I229_I0.6810.71
552_Q556_E0.6790.71
352_A355_V0.6780.71
758_V761_Y0.6760.71
22_L149_Y0.6760.71
248_V313_G0.6760.71
691_E707_K0.6750.71
133_E512_Q0.6750.71
390_I393_I0.6740.70
249_E295_E0.6730.70
536_Q638_T0.6720.70
23_D30_V0.6720.70
34_L171_S0.6700.70
777_T781_G0.6700.70
392_P396_L0.6700.70
246_A262_H0.6680.70
373_A485_I0.6670.70
34_L336_A0.6660.69
61_K64_K0.6660.69
537_E553_P0.6660.69
472_E475_L0.6650.69
54_V77_Y0.6650.69
127_L149_Y0.6640.69
92_M97_S0.6640.69
373_A484_Q0.6640.69
405_E408_T0.6630.69
548_Y621_N0.6630.69
278_A291_A0.6630.69
192_N516_K0.6620.69
653_G724_I0.6620.69
536_Q588_D0.6600.69
383_L457_A0.6600.69
270_K301_M0.6600.69
672_V675_K0.6590.69
131_A134_L0.6570.68
370_L489_L0.6560.68
501_V504_E0.6550.68
650_T682_L0.6550.68
771_V817_R0.6540.68
27_S31_G0.6530.68
703_V764_K0.6520.68
793_D809_V0.6520.68
196_A208_L0.6520.68
249_E261_V0.6510.68
57_N126_R0.6500.68
370_L374_R0.6500.68
490_R500_E0.6480.67
637_V640_F0.6470.67
394_I397_I0.6460.67
217_F330_F0.6460.67
542_T552_Q0.6460.67
374_R485_I0.6450.67
253_K256_R0.6450.67
468_G471_H0.6450.67
92_M183_P0.6430.67
355_V503_R0.6430.67
224_N522_T0.6430.67
293_R302_R0.6410.67
83_S89_I0.6410.67
55_L64_K0.6390.66
705_R763_T0.6390.66
217_F240_V0.6390.66
161_T354_F0.6380.66
403_P407_K0.6380.66
204_S234_R0.6370.66
69_V73_V0.6370.66
68_R149_Y0.6360.66
592_C619_I0.6360.66
163_I194_C0.6360.66
260_I302_R0.6360.66
36_D158_V0.6340.66
632_T648_M0.6330.66
281_V291_A0.6320.65
362_V365_R0.6320.65
162_K505_E0.6320.65
331_G335_V0.6320.65
813_S826_R0.6300.65
582_L590_I0.6290.65
271_A278_A0.6290.65
396_L399_H0.6290.65
729_G757_A0.6280.65
63_Y126_R0.6270.65
580_R634_I0.6250.65
643_G659_V0.6240.64
790_D793_D0.6230.64
206_E209_M0.6230.64
193_G203_I0.6230.64
672_V717_N0.6230.64
777_T780_N0.6220.64
683_I732_V0.6220.64
31_G87_D0.6220.64
146_V155_I0.6220.64
553_P556_E0.6220.64
409_A455_A0.6220.64
400_A406_A0.6210.64
242_I330_F0.6200.64
544_S576_D0.6190.64
462_R467_T0.6190.64
477_E481_L0.6190.64
93_A105_G0.6190.64
209_M230_E0.6180.64
53_N138_L0.6170.64
74_I120_M0.6170.64
61_K126_R0.6170.64
663_F718_T0.6160.63
757_A761_Y0.6160.63
744_I786_A0.6160.63
149_Y239_K0.6150.63
68_R152_T0.6150.63
244_A303_I0.6140.63
60_N126_R0.6140.63
28_V176_V0.6130.63
66_S153_E0.6130.63
573_K615_R0.6120.63
269_N273_L0.6110.63
388_A398_R0.6100.63
37_V336_A0.6100.63
220_A264_I0.6100.63
244_A273_L0.6100.63
31_G337_L0.6090.63
249_E258_T0.6080.62
641_E644_V0.6070.62
221_A245_R0.6060.62
635_L646_V0.6060.62
51_A73_V0.6050.62
298_K551_Y0.6040.62
768_T771_V0.6040.62
490_R496_D0.6030.62
379_I453_Q0.6020.62
601_S664_N0.6020.62
816_G820_Q0.6020.62
44_V87_D0.6020.62
120_M150_D0.6010.62
708_E711_V0.6010.62
560_Q566_G0.6010.62
394_I398_R0.6000.61
87_D117_A0.6000.61
703_V771_V0.5980.61
55_L120_M0.5970.61
48_V98_L0.5960.61
197_Y207_G0.5960.61
700_E727_G0.5960.61
461_L468_G0.5960.61
336_A346_N0.5950.61
202_D207_G0.5950.61
194_C498_L0.5940.61
277_I324_T0.5940.61
44_V88_T0.5930.61
51_A64_K0.5930.61
388_A468_G0.5930.61
137_D362_V0.5930.61
645_K659_V0.5920.60
401_P472_E0.5920.60
694_V737_V0.5910.60
210_E226_R0.5910.60
45_H87_D0.5910.60
389_N393_I0.5910.60
172_S330_F0.5900.60
194_C197_Y0.5900.60
260_I303_I0.5900.60
775_K815_V0.5900.60
384_A471_H0.5890.60
221_A242_I0.5880.60
535_T587_H0.5880.60
120_M149_Y0.5870.60
459_L474_L0.5870.60
460_D464_Q0.5870.60
248_V257_E0.5860.60
602_M623_L0.5860.60
357_H361_V0.5860.60
529_N606_Q0.5860.60
209_M212_I0.5850.60
134_L163_I0.5850.60
410_L449_Y0.5840.59
640_F644_V0.5840.59
766_R770_G0.5840.59
407_K459_L0.5840.59
53_N135_M0.5840.59
510_R516_K0.5840.59
138_L145_F0.5830.59
596_R681_E0.5820.59
271_A274_I0.5820.59
456_Q464_Q0.5820.59
592_C631_I0.5820.59
795_I807_T0.5820.59
188_T515_D0.5810.59
387_L470_E0.5810.59
697_F744_I0.5800.59
74_I82_D0.5790.59
380_L477_E0.5780.59
76_K152_T0.5780.59
695_M705_R0.5780.59
182_I351_I0.5780.59
582_L636_P0.5780.59
298_K301_M0.5780.59
198_I355_V0.5770.58
355_V499_M0.5770.58
772_I776_V0.5770.58
100_Y168_V0.5760.58
270_K296_S0.5760.58
93_A103_V0.5760.58
758_V788_Q0.5750.58
228_G232_A0.5750.58
369_E487_E0.5750.58
652_N729_G0.5740.58
385_V448_Y0.5740.58
203_I352_A0.5730.58
646_V687_L0.5730.58
53_N127_L0.5730.58
534_I605_Y0.5730.58
64_K72_D0.5730.58
229_I233_Y0.5720.58
746_T783_V0.5720.58
27_S30_V0.5710.58
18_K22_L0.5710.58
546_Q575_E0.5710.58
290_S311_A0.5710.58
181_N330_F0.5710.58
199_D500_E0.5710.58
111_S115_D0.5710.58
273_L326_L0.5690.57
353_A357_H0.5690.57
239_K333_N0.5690.57
700_E729_G0.5670.57
705_R738_P0.5660.57
590_I604_V0.5660.57
133_E509_V0.5650.57
267_Q459_L0.5640.57
791_D814_I0.5640.57
373_A488_L0.5640.57
599_V666_L0.5640.57
172_S267_Q0.5640.57
21_Y333_N0.5630.57
467_T472_E0.5630.57
243_R321_Y0.5630.57
292_L303_I0.5630.57
45_H84_A0.5620.57
601_S665_R0.5620.57
363_T495_A0.5620.57
548_Y616_G0.5610.56
63_Y116_S0.5610.56
387_L467_T0.5600.56
137_D365_R0.5600.56
191_I498_L0.5600.56
785_G797_M0.5600.56
336_A345_M0.5590.56
589_H640_F0.5580.56
689_S708_E0.5580.56
412_A449_Y0.5580.56
259_I316_V0.5580.56
319_N323_Q0.5580.56
115_D270_K0.5580.56
315_V534_I0.5580.56
389_N448_Y0.5570.56
284_K287_E0.5570.56
114_G117_A0.5570.56
403_P460_D0.5570.56
593_F673_A0.5570.56
232_A347_L0.5570.56
64_K120_M0.5560.56
395_E453_Q0.5560.56
648_M663_F0.5560.56
496_D499_M0.5550.56
742_G790_D0.5550.56
663_F717_N0.5530.55
576_D616_G0.5530.55
632_T676_L0.5530.55
744_I788_Q0.5520.55
51_A120_M0.5520.55
494_S498_L0.5520.55
166_L182_I0.5500.55
274_I294_D0.5500.55
747_A797_M0.5500.55
568_S803_T0.5490.55
13_I23_D0.5490.55
803_T825_I0.5490.55
202_D348_K0.5480.55
307_V387_L0.5480.55
666_L669_A0.5470.55
697_F734_S0.5470.55
823_I827_T0.5470.55
339_H345_M0.5460.54
161_T358_R0.5460.54
214_G698_S0.5460.54
168_V509_V0.5460.54
234_R346_N0.5450.54
776_V783_V0.5450.54
642_E664_N0.5440.54
550_K616_G0.5440.54
742_G788_Q0.5440.54
22_L84_A0.5430.54
502_I509_V0.5420.54
657_K794_Q0.5420.54
388_A448_Y0.5410.54
189_E209_M0.5410.54
287_E308_K0.5410.54
775_K818_N0.5410.54
748_T780_N0.5410.54
368_F375_D0.5410.54
255_G309_R0.5400.54
168_V188_T0.5400.54
774_I820_Q0.5400.54
57_N89_I0.5400.54
655_V696_L0.5390.53
251_D264_I0.5390.53
52_M103_V0.5390.53
256_R306_E0.5390.53
77_Y138_L0.5390.53
455_A728_E0.5390.53
791_D809_V0.5390.53
97_S275_E0.5390.53
748_T751_G0.5380.53
13_I17_L0.5380.53
384_A479_K0.5380.53
57_N62_A0.5370.53
141_E368_F0.5370.53
451_T481_L0.5370.53
17_L336_A0.5370.53
592_C602_M0.5360.53
776_V781_G0.5360.53
244_A328_V0.5360.53
759_A763_T0.5350.53
195_L506_L0.5350.53
41_L72_D0.5340.53
362_V499_M0.5340.53
401_P467_T0.5340.53
25_A537_E0.5340.53
141_E154_K0.5330.53
207_G211_H0.5330.53
27_S109_F0.5330.53
55_L74_I0.5320.53
395_E409_A0.5320.53
649_A694_V0.5320.53
209_M213_P0.5310.52
221_A301_M0.5310.52
629_E676_L0.5310.52
640_F660_L0.5310.52
62_A68_R0.5310.52
589_H603_K0.5310.52
775_K820_Q0.5310.52
698_S726_L0.5300.52
264_I271_A0.5300.52
249_E306_E0.5300.52
106_Q132_H0.5290.52
45_H85_V0.5280.52
367_I489_L0.5270.52
402_T464_Q0.5270.52
231_E235_T0.5270.52
396_L462_R0.5250.52
134_L159_M0.5250.52
83_S117_A0.5250.52
50_Y138_L0.5240.51
468_G472_E0.5240.51
691_E709_S0.5240.51
733_V783_V0.5240.51
593_F682_L0.5230.51
193_G351_I0.5230.51
326_L767_A0.5230.51
686_D736_I0.5230.51
354_F567_K0.5230.51
60_N106_Q0.5220.51
693_E740_G0.5220.51
755_R809_V0.5220.51
273_L277_I0.5220.51
145_F679_G0.5220.51
345_M350_I0.5220.51
70_V74_I0.5210.51
406_A410_L0.5200.51
54_V72_D0.5190.51
31_G84_A0.5190.51
193_G196_A0.5180.51
697_F703_V0.5180.51
377_A481_L0.5180.51
528_I533_L0.5180.51
703_V773_S0.5180.51
492_L498_L0.5180.51
214_G676_L0.5170.50
278_A282_K0.5160.50
698_S702_K0.5160.50
23_D26_M0.5160.50
819_T824_L0.5160.50
767_A770_G0.5160.50
55_L58_D0.5160.50
391_D397_I0.5160.50
479_K486_A0.5160.50
237_R331_G0.5160.50
662_E713_A0.5160.50
21_Y106_Q0.5150.50
237_R242_I0.5150.50
264_I270_K0.5150.50
274_I297_D0.5150.50
55_L153_E0.5150.50
286_V326_L0.5150.50
776_V820_Q0.5140.50
207_G507_E0.5130.50
27_S337_L0.5130.50
85_V286_V0.5120.50
135_M138_L0.5120.50
725_R728_E0.5120.50
11_V16_E0.5120.50
84_A96_F0.5120.50
649_A686_D0.5120.50
210_E516_K0.5120.50
161_T166_L0.5110.50
725_R826_R0.5110.50
809_V827_T0.5110.50
407_K455_A0.5110.50
16_E27_S0.5110.50
403_P465_K0.5110.50
551_Y586_T0.5110.50
237_R333_N0.5110.50
457_A468_G0.5110.50
45_H96_F0.5110.50
763_T768_T0.5100.50
405_E694_V0.5100.50
219_T266_Y0.5100.50
736_I744_I0.5100.50
706_F710_S0.5100.50
57_N125_I0.5100.50
202_D504_E0.5100.50
702_K772_I0.5100.50
377_A380_L0.5090.49
817_R821_G0.5090.49
358_R505_E0.5090.49
264_I301_M0.5080.49
130_I513_F0.5080.49
47_R78_H0.5080.49
295_E306_E0.5070.49
557_Y623_L0.5070.49
83_S120_M0.5070.49
145_F157_D0.5070.49
85_V96_F0.5060.49
602_M622_L0.5060.49
190_V727_G0.5060.49
163_I358_R0.5060.49
755_R791_D0.5060.49
696_L706_F0.5050.49
500_E503_R0.5040.49
746_T815_V0.5040.49
477_E480_E0.5040.49
543_L631_I0.5030.49
374_R377_A0.5030.49
274_I281_V0.5030.49
752_Y780_N0.5030.49
277_I320_L0.5020.48
776_V818_N0.5020.48
749_Q781_G0.5020.48
296_S299_D0.5020.48
368_F453_Q0.5020.48
535_T586_T0.5020.48
624_P669_A0.5020.48
11_V14_E0.5020.48
62_A127_L0.5010.48
74_I77_Y0.5010.48
199_D511_E0.5010.48
69_V85_V0.5010.48
203_I351_I0.5010.48
21_Y358_R0.5010.48
384_A481_L0.5010.48
683_I686_D0.5000.48
136_A508_L0.5000.48
607_L622_L0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1zvuA 2 0.7623 100 0.248 Contact Map
2inrA 2 0.5051 100 0.377 Contact Map
4i3hA 2 0.5554 100 0.378 Contact Map
2novA 2 0.5177 100 0.381 Contact Map
2xcsB 2 0.5497 100 0.386 Contact Map
2xkjE 2 0.5451 100 0.392 Contact Map
4ckkA 2 0.5566 100 0.396 Contact Map
3ilwA 2 0.5246 100 0.397 Contact Map
4gfhA 2 0.5371 100 0.505 Contact Map
3l4jA 1 0.5371 100 0.525 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0189 seconds.