GREMLIN Database
GLNP - Glutamine transport system permease protein GlnP
UniProt: P0AEQ6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10388
Length: 219 (203)
Sequences: 20660 (12597)
Seq/√Len: 884.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_G98_M3.2721.00
152_G209_L3.1931.00
124_G134_T3.1391.00
186_R189_E3.0211.00
93_A165_F2.8691.00
20_K24_W2.8231.00
130_S133_E2.7191.00
43_A55_A2.5401.00
177_G194_V2.4611.00
132_W136_R2.2601.00
125_L134_T2.2541.00
65_T70_Q2.2341.00
207_F211_R2.1841.00
40_A106_A2.1641.00
120_F142_L2.1181.00
121_R134_T2.1171.00
50_I54_V2.0211.00
28_L94_V1.9951.00
40_A102_G1.9731.00
121_R125_L1.9121.00
175_R179_E1.8881.00
50_I53_H1.8661.00
49_W53_H1.8031.00
21_M24_W1.7901.00
41_G109_T1.7901.00
36_I102_G1.7751.00
44_R56_L1.7741.00
24_W90_F1.6911.00
203_L207_F1.6891.00
16_I20_K1.6771.00
30_L155_W1.6461.00
45_T114_L1.6141.00
74_I96_T1.5821.00
211_R214_R1.5781.00
207_F210_R1.5691.00
199_L203_L1.5631.00
17_E20_K1.5551.00
19_A201_I1.5551.00
21_M170_V1.5411.00
115_S146_R1.5391.00
133_E137_Y1.5371.00
131_R135_I1.5191.00
25_I165_F1.5171.00
177_G190_I1.5031.00
38_L109_T1.5001.00
130_S134_T1.4991.00
112_A147_M1.4971.00
26_S159_I1.4721.00
107_E110_R1.4671.00
181_I187_A1.4651.00
14_L17_E1.4541.00
59_I106_A1.4541.00
33_G101_S1.4371.00
105_I151_L1.4081.00
125_L131_R1.3891.00
129_L133_E1.3861.00
208_I211_R1.3631.00
176_Q179_E1.3381.00
88_D91_T1.3371.00
133_E136_R1.3341.00
40_A55_A1.3211.00
49_W52_N1.3161.00
70_Q100_N1.2881.00
105_I154_Q1.2781.00
28_L98_M1.2761.00
48_G53_H1.2591.00
175_R178_Q1.2511.00
109_T147_M1.2471.00
26_S162_T1.2441.00
110_R114_L1.2351.00
48_G51_A1.2231.00
24_W28_L1.2231.00
12_I16_I1.2041.00
32_G94_V1.2031.00
124_G138_V1.2001.00
35_V39_L1.1931.00
39_L43_A1.1841.00
121_R139_I1.1821.00
14_L176_Q1.1551.00
53_H57_V1.1451.00
171_A175_R1.1401.00
131_R134_T1.1331.00
90_F94_V1.1261.00
62_I99_I1.1251.00
94_V98_M1.1191.00
37_G105_I1.1181.00
26_S155_W1.1061.00
71_V96_T1.0961.00
54_V57_V1.0951.00
108_I154_Q1.0951.00
71_V165_F1.0871.00
91_T94_V1.0831.00
17_E21_M1.0711.00
52_N56_L1.0601.00
13_P17_E1.0581.00
129_L137_Y1.0551.00
178_Q181_I1.0541.00
70_Q74_I1.0531.00
65_T100_N1.0531.00
113_V139_I1.0451.00
181_I191_W1.0431.00
60_E203_L1.0361.00
210_R214_R1.0321.00
211_R215_R1.0211.00
54_V58_F1.0201.00
179_E183_G1.0031.00
89_P169_G0.9951.00
43_A46_F0.9801.00
159_I201_I0.9771.00
34_L151_L0.9731.00
44_R107_E0.9631.00
189_E192_S0.9611.00
55_A106_A0.9591.00
135_I140_L0.9581.00
108_I150_P0.9531.00
45_T113_V0.9501.00
118_K122_E0.9411.00
90_F170_V0.9361.00
116_I143_A0.9341.00
29_G98_M0.9301.00
67_I161_D0.9281.00
124_G129_L0.9251.00
74_I92_A0.9211.00
157_I161_D0.9161.00
62_I103_A0.9141.00
67_I100_N0.9041.00
30_L158_S0.9031.00
204_V208_I0.9021.00
184_N187_A0.9021.00
43_A51_A0.9001.00
28_L32_G0.8871.00
208_I212_L0.8871.00
29_G158_S0.8831.00
31_A35_V0.8811.00
167_V171_A0.8801.00
41_G113_V0.8751.00
146_R150_P0.8731.00
112_A146_R0.8671.00
135_I139_I0.8661.00
57_V60_E0.8641.00
180_I190_I0.8601.00
210_R213_E0.8571.00
58_F102_G0.8561.00
47_G52_N0.8541.00
73_F77_A0.8531.00
163_S198_Y0.8471.00
165_F170_V0.8471.00
22_T159_I0.8461.00
71_V164_L0.8401.00
72_M76_F0.8371.00
77_A81_A0.8371.00
60_E199_L0.8351.00
42_F135_I0.8291.00
48_G54_V0.8291.00
19_A197_F0.8261.00
70_Q96_T0.8261.00
27_V31_A0.8221.00
101_S154_Q0.8171.00
41_G45_T0.8171.00
53_H56_L0.8091.00
116_I146_R0.8041.00
13_P16_I0.7991.00
91_T95_V0.7981.00
177_G181_I0.7961.00
58_F62_I0.7951.00
165_F172_E0.7941.00
38_L140_L0.7901.00
36_I98_M0.7901.00
48_G52_N0.7831.00
159_I205_L0.7831.00
113_V143_A0.7771.00
46_F55_A0.7751.00
18_G176_Q0.7731.00
56_L60_E0.7721.00
28_L90_F0.7721.00
193_A197_F0.7691.00
118_K121_R0.7671.00
121_R131_R0.7571.00
119_G123_A0.7571.00
71_V168_I0.7541.00
68_V167_V0.7521.00
205_L209_L0.7471.00
171_A176_Q0.7461.00
101_S158_S0.7461.00
33_G105_I0.7461.00
183_G186_R0.7441.00
19_A173_L0.7401.00
97_I162_T0.7291.00
159_I202_T0.7281.00
21_M90_F0.7271.00
105_I109_T0.7221.00
200_I204_V0.7221.00
93_A168_I0.7191.00
58_F103_A0.7171.00
29_G97_I0.7171.00
25_I29_G0.7161.00
89_P170_V0.7151.00
51_A54_V0.7151.00
109_T113_V0.7121.00
73_F192_S0.7031.00
46_F131_R0.7011.00
28_L31_A0.6941.00
75_Y92_A0.6941.00
23_L27_V0.6891.00
25_I93_A0.6891.00
191_W194_V0.6851.00
32_G35_V0.6821.00
44_R47_G0.6821.00
139_I142_L0.6791.00
100_N161_D0.6781.00
75_Y168_I0.6771.00
206_S210_R0.6771.00
25_I170_V0.6751.00
192_S195_A0.6751.00
173_L176_Q0.6681.00
40_A43_A0.6671.00
26_S30_L0.6651.00
192_S196_V0.6641.00
163_S166_I0.6641.00
25_I90_F0.6611.00
150_P153_N0.6571.00
77_A80_M0.6561.00
191_W195_A0.6551.00
89_P92_A0.6501.00
196_V200_I0.6471.00
212_L216_M0.6471.00
194_V198_Y0.6471.00
166_I175_R0.6441.00
44_R52_N0.6381.00
16_I19_A0.6381.00
119_G122_E0.6371.00
181_I190_I0.6331.00
101_S161_D0.6321.00
203_L206_S0.6301.00
97_I165_F0.6281.00
22_T198_Y0.6241.00
43_A54_V0.6221.00
61_V65_T0.6211.00
118_K125_L0.6191.00
97_I158_S0.6171.00
37_G109_T0.6171.00
154_Q157_I0.6131.00
174_T191_W0.6041.00
37_G41_G0.5971.00
36_I39_L0.5971.00
209_L212_L0.5961.00
62_I70_Q0.5961.00
98_M102_G0.5901.00
204_V211_R0.5891.00
44_R59_I0.5871.00
32_G36_I0.5861.00
101_S105_I0.5851.00
155_W205_L0.5801.00
20_K23_L0.5791.00
177_G180_I0.5771.00
24_W91_T0.5741.00
30_L34_L0.5711.00
44_R106_A0.5691.00
36_I40_A0.5671.00
178_Q182_A0.5671.00
75_Y89_P0.5651.00
35_V98_M0.5641.00
185_F188_L0.5621.00
122_E137_Y0.5581.00
204_V207_F0.5571.00
148_L212_L0.5561.00
67_I97_I0.5561.00
75_Y87_I0.5551.00
34_L109_T0.5541.00
117_H146_R0.5531.00
93_A170_V0.5531.00
149_P213_E0.5501.00
180_I184_N0.5481.00
38_L144_L0.5461.00
174_T194_V0.5451.00
130_S137_Y0.5441.00
47_G131_R0.5441.00
148_L216_M0.5431.00
60_E206_S0.5421.00
124_G127_L0.5421.00
194_V197_F0.5401.00
129_L134_T0.5391.00
121_R135_I0.5381.00
188_L192_S0.5381.00
21_M172_E0.5371.00
163_S174_T0.5351.00
89_P168_I0.5351.00
35_V38_L0.5311.00
15_L197_F0.5251.00
172_E176_Q0.5251.00
82_F85_L0.5221.00
113_V135_I0.5201.00
37_G106_A0.5191.00
17_E24_W0.5191.00
47_G50_I0.5181.00
174_T198_Y0.5171.00
112_A150_P0.5171.00
100_N104_Y0.5141.00
207_F214_R0.5081.00
87_I91_T0.5081.00
34_L105_I0.5081.00
64_G100_N0.5081.00
199_L202_T0.5051.00
34_L155_W0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ymuD 2 0.9817 100 0.359 Contact Map
2onkC 2 0.9635 99.9 0.426 Contact Map
3rlfF 1 0.9452 99.9 0.434 Contact Map
3d31C 2 0.9452 99.9 0.438 Contact Map
3tuiA 2 0.9543 99.9 0.442 Contact Map
4tquM 1 0.9909 99.9 0.467 Contact Map
3rlfG 1 0.9954 99.9 0.487 Contact Map
4tquN 1 0.9543 99.9 0.519 Contact Map
1hgvA 8 0.21 2.6 0.957 Contact Map
4mt1A 3 0.79 2.1 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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