GCL - ECOLI - GREMLIN Contacts

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GCL - Glyoxylate carboligase

UniProt:	P0AEP7	Sequences: MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFMHYE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11583
Length:	593 (536)
Sequences:	14291 (9038)
Seq/√Len:	390.4

ECOLI - GCL ILVI ILVB ILVG POXB OXC MEND
BACSU - ILVX YDAP IOLD ILVB MEND
HALSA - MEND
SULSO - Q7LXT8 Q97UP3 Q97ZB3 Q97U16 Q97V62 Q97XR3 Q980V7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
513_K	516_E	4.912	1.00
472_N	552_E	3.768	1.00
378_E	532_A	3.641	1.00
55_S	86_A	3.619	1.00
228_E	248_H	3.542	1.00
523_I	537_Q	3.402	1.00
222_L	327_T	3.187	1.00
20_T	68_N	3.024	1.00
527_K	530_D	2.984	1.00
524_R	554_I	2.965	1.00
194_E	332_V	2.863	1.00
222_L	323_K	2.799	1.00
382_A	536_E	2.722	1.00
320_S	325_A	2.667	1.00
210_A	223_L	2.563	1.00
15_E	42_G	2.563	1.00
64_A	435_D	2.553	1.00
247_D	407_F	2.518	1.00
523_I	549_V	2.508	1.00
521_K	547_V	2.483	1.00
378_E	381_K	2.449	1.00
526_F	530_D	2.440	1.00
21_T	44_R	2.434	1.00
196_A	299_V	2.361	1.00
428_A	442_A	2.345	1.00
277_I	322_A	2.327	1.00
271_S	274_V	2.277	1.00
301_I	325_A	2.259	1.00
523_I	534_A	2.256	1.00
74_G	83_M	2.240	1.00
541_L	547_V	2.212	1.00
381_K	532_A	2.157	1.00
521_K	537_Q	2.144	1.00
510_D	513_K	2.123	1.00
524_R	552_E	2.121	1.00
450_Q	518_L	2.104	1.00
69_I	151_R	2.100	1.00
98_L	147_F	2.065	1.00
81_T	85_T	2.052	1.00
8_D	36_A	2.044	1.00
276_G	279_N	2.031	1.00
435_D	438_R	2.022	1.00
87_L	99_C	2.022	1.00
48_A	54_A	2.016	1.00
199_M	316_L	1.998	1.00
514_V	517_G	1.996	1.00
199_M	273_M	1.979	1.00
208_I	227_A	1.922	1.00
101_T	159_L	1.917	1.00
199_M	297_K	1.886	1.00
525_V	534_A	1.868	1.00
121_A	124_K	1.864	1.00
512_V	522_A	1.864	1.00
69_I	98_L	1.858	1.00
384_G	387_V	1.853	1.00
142_V	160_V	1.841	1.00
12_Y	16_K	1.837	1.00
380_N	405_H	1.823	1.00
432_C	465_P	1.802	1.00
449_F	453_I	1.801	1.00
227_A	234_V	1.797	1.00
59_E	63_R	1.786	1.00
460_A	520_C	1.784	1.00
195_K	198_E	1.778	1.00
229_L	330_V	1.776	1.00
8_D	39_K	1.774	1.00
200_L	275_F	1.767	1.00
229_L	334_Q	1.736	1.00
198_E	202_Q	1.735	1.00
536_E	540_A	1.733	1.00
225_Q	229_L	1.733	1.00
532_A	536_E	1.716	1.00
189_S	192_Q	1.704	1.00
190_R	328_L	1.694	1.00
538_A	551_V	1.693	1.00
521_K	549_V	1.676	1.00
530_D	533_P	1.675	1.00
208_I	275_F	1.671	1.00
388_C	431_V	1.667	1.00
470_L	550_V	1.661	1.00
224_Q	228_E	1.660	1.00
392_T	444_S	1.653	1.00
208_I	232_V	1.646	1.00
377_E	381_K	1.625	1.00
118_D	121_A	1.608	1.00
423_W	427_A	1.595	1.00
34_Y	45_H	1.575	1.00
221_A	225_Q	1.574	1.00
24_G	45_H	1.570	1.00
379_M	443_I	1.569	1.00
392_T	448_D	1.569	1.00
526_F	554_I	1.566	1.00
277_I	301_I	1.559	1.00
135_E	138_L	1.559	1.00
516_E	521_K	1.552	1.00
127_S	159_L	1.545	1.00
131_V	160_V	1.540	1.00
413_I	431_V	1.532	1.00
231_S	250_L	1.526	1.00
203_A	206_P	1.510	1.00
533_P	537_Q	1.504	1.00
308_I	319_V	1.500	1.00
12_Y	15_E	1.498	1.00
345_R	349_V	1.492	1.00
374_R	528_P	1.486	1.00
459_G	520_C	1.484	1.00
10_A	162_L	1.477	1.00
512_V	524_R	1.477	1.00
432_C	464_I	1.468	1.00
234_V	244_I	1.462	1.00
13_V	144_Q	1.459	1.00
15_E	40_H	1.457	1.00
128_K	156_G	1.453	1.00
456_L	520_C	1.449	1.00
382_A	532_A	1.440	1.00
136_A	169_A	1.427	1.00
411_H	438_R	1.427	1.00
374_R	378_E	1.419	1.00
348_W	352_C	1.418	1.00
200_L	273_M	1.410	1.00
100_I	162_L	1.409	1.00
53_G	455_E	1.408	1.00
10_A	143_L	1.405	1.00
533_P	536_E	1.401	1.00
192_Q	195_K	1.399	1.00
469_V	551_V	1.398	1.00
197_V	332_V	1.397	1.00
348_W	355_R	1.396	1.00
387_V	439_N	1.394	1.00
459_G	466_Y	1.379	1.00
83_M	99_C	1.373	1.00
378_E	382_A	1.372	1.00
197_V	329_L	1.371	1.00
469_V	535_F	1.361	1.00
48_A	57_M	1.356	1.00
384_G	439_N	1.343	1.00
226_F	230_T	1.342	1.00
17_E	147_F	1.342	1.00
383_F	441_V	1.336	1.00
98_L	150_M	1.335	1.00
87_L	97_I	1.334	1.00
69_I	147_F	1.331	1.00
106_R	165_D	1.328	1.00
441_V	539_K	1.318	1.00
453_I	514_V	1.316	1.00
385_R	407_F	1.314	1.00
433_A	464_I	1.308	1.00
273_M	299_V	1.307	1.00
44_R	462_F	1.306	1.00
80_G	101_T	1.305	1.00
375_V	553_V	1.303	1.00
421_L	451_F	1.302	1.00
225_Q	330_V	1.300	1.00
133_V	139_V	1.294	1.00
203_A	273_M	1.289	1.00
467_I	538_A	1.284	1.00
17_E	144_Q	1.279	1.00
270_A	351_D	1.279	1.00
353_Q	357_R	1.279	1.00
469_V	553_V	1.277	1.00
21_T	433_A	1.275	1.00
541_L	549_V	1.272	1.00
439_N	539_K	1.272	1.00
521_K	541_L	1.271	1.00
432_C	439_N	1.270	1.00
429_L	459_G	1.270	1.00
346_K	350_A	1.267	1.00
207_V	271_S	1.264	1.00
353_Q	356_K	1.263	1.00
55_S	83_M	1.261	1.00
188_A	325_A	1.254	1.00
512_V	516_E	1.253	1.00
465_P	547_V	1.252	1.00
138_L	141_R	1.249	1.00
277_I	326_L	1.244	1.00
223_L	326_L	1.243	1.00
226_F	326_L	1.241	1.00
297_K	315_D	1.238	1.00
193_I	332_V	1.238	1.00
46_I	433_A	1.235	1.00
143_L	160_V	1.235	1.00
370_V	553_V	1.233	1.00
352_C	356_K	1.232	1.00
465_P	546_R	1.229	1.00
514_V	518_L	1.227	1.00
226_F	330_V	1.227	1.00
309_G	314_P	1.220	1.00
141_R	145_Q	1.216	1.00
288_S	291_K	1.212	1.00
59_E	89_S	1.210	1.00
323_K	327_T	1.208	1.00
370_V	375_V	1.206	1.00
531_I	553_V	1.203	1.00
442_A	468_H	1.202	1.00
224_Q	245_P	1.198	1.00
474_A	508_G	1.196	1.00
515_A	520_C	1.195	1.00
194_E	198_E	1.193	1.00
350_A	354_Q	1.191	1.00
15_E	41_G	1.188	1.00
7_V	36_A	1.183	1.00
23_F	61_Y	1.182	1.00
62_T	96_P	1.182	1.00
5_R	170_E	1.181	1.00
61_Y	434_A	1.178	1.00
324_A	327_T	1.176	1.00
520_C	550_V	1.168	1.00
541_L	546_R	1.167	1.00
328_L	331_E	1.162	1.00
9_A	171_I	1.161	1.00
321_D	324_A	1.161	1.00
388_C	440_V	1.161	1.00
163_P	166_V	1.159	1.00
457_A	461_Q	1.156	1.00
388_C	435_D	1.156	1.00
513_K	517_G	1.155	1.00
13_V	143_L	1.149	1.00
182_P	186_P	1.148	1.00
6_A	139_V	1.148	1.00
225_Q	228_E	1.147	1.00
197_V	201_I	1.147	1.00
88_Y	418_A	1.146	1.00
350_A	353_Q	1.141	1.00
195_K	199_M	1.140	1.00
20_T	44_R	1.138	1.00
534_A	551_V	1.136	1.00
385_R	408_K	1.135	1.00
22_A	37_M	1.133	1.00
224_Q	244_I	1.132	1.00
19_I	71_V	1.130	1.00
214_V	223_L	1.129	1.00
84_I	122_I	1.126	1.00
197_V	333_A	1.125	1.00
131_V	145_Q	1.124	1.00
266_A	270_A	1.118	1.00
515_A	550_V	1.113	1.00
236_P	251_M	1.110	1.00
72_C	83_M	1.109	1.00
349_V	353_Q	1.109	1.00
252_A	267_T	1.108	1.00
131_V	142_V	1.106	1.00
107_A	165_D	1.105	1.00
351_D	355_R	1.105	1.00
208_I	226_F	1.103	1.00
354_Q	358_T	1.102	1.00
190_R	332_V	1.101	1.00
222_L	330_V	1.098	1.00
65_T	434_A	1.097	1.00
537_Q	541_L	1.090	1.00
241_W	246_D	1.089	1.00
225_Q	327_T	1.087	1.00
60_G	64_A	1.087	1.00
5_R	8_D	1.085	1.00
228_E	250_L	1.084	1.00
196_A	316_L	1.083	1.00
222_L	225_Q	1.082	1.00
149_L	158_V	1.080	1.00
59_E	95_I	1.079	1.00
205_R	270_A	1.078	1.00
523_I	551_V	1.078	1.00
522_A	550_V	1.077	1.00
531_I	535_F	1.074	1.00
84_I	126_V	1.073	1.00
64_A	431_V	1.071	1.00
210_A	214_V	1.070	1.00
201_I	336_M	1.067	1.00
106_R	169_A	1.067	1.00
188_A	328_L	1.063	1.00
91_S	157_P	1.060	1.00
276_G	281_F	1.058	1.00
122_I	126_V	1.056	1.00
206_P	272_D	1.054	1.00
432_C	440_V	1.050	1.00
224_Q	248_H	1.048	1.00
133_V	142_V	1.046	1.00
81_T	122_I	1.045	1.00
208_I	223_L	1.043	1.00
432_C	436_P	1.042	1.00
53_G	452_L	1.041	1.00
36_A	39_K	1.036	1.00
227_A	244_I	1.034	1.00
74_G	99_C	1.033	1.00
386_D	438_R	1.031	1.00
9_A	140_P	1.031	1.00
127_S	130_A	1.029	1.00
21_T	46_I	1.028	1.00
244_I	248_H	1.027	1.00
201_I	334_Q	1.027	1.00
235_I	252_A	1.027	1.00
46_I	462_F	1.021	1.00
515_A	522_A	1.016	1.00
383_F	389_Y	1.012	1.00
286_T	289_V	1.008	1.00
55_S	72_C	1.005	1.00
196_A	318_I	1.004	1.00
30_I	33_F	1.001	1.00
221_A	224_Q	1.000	1.00
262_R	266_A	0.999	1.00
207_V	235_I	0.999	1.00
525_V	530_D	0.996	1.00
424_T	442_A	0.994	1.00
227_A	250_L	0.993	1.00
467_I	549_V	0.990	1.00
10_A	100_I	0.990	1.00
389_Y	404_L	0.989	1.00
537_Q	540_A	0.988	1.00
371_K	559_T	0.987	1.00
439_N	467_I	0.986	1.00
72_C	99_C	0.983	1.00
226_F	333_A	0.980	1.00
432_C	437_K	0.980	1.00
352_C	355_R	0.975	1.00
425_I	449_F	0.970	1.00
474_A	554_I	0.964	1.00
202_Q	297_K	0.963	1.00
324_A	328_L	0.959	1.00
22_A	71_V	0.959	1.00
10_A	33_F	0.958	1.00
538_A	549_V	0.956	1.00
525_V	531_I	0.956	1.00
151_R	155_P	0.954	1.00
318_I	325_A	0.954	1.00
203_A	272_D	0.953	1.00
314_P	317_G	0.953	1.00
456_L	550_V	0.952	1.00
470_L	511_H	0.952	1.00
432_C	547_V	0.951	1.00
449_F	470_L	0.951	1.00
512_V	552_E	0.950	1.00
130_A	159_L	0.948	1.00
129_M	149_L	0.946	1.00
380_N	404_L	0.946	1.00
390_V	442_A	0.944	1.00
87_L	123_A	0.944	1.00
202_Q	273_M	0.943	1.00
33_F	162_L	0.939	1.00
103_Q	161_D	0.939	1.00
183_V	186_P	0.936	1.00
201_I	333_A	0.934	1.00
109_L	132_T	0.934	1.00
390_V	440_V	0.931	1.00
225_Q	334_Q	0.929	1.00
57_M	459_G	0.929	1.00
80_G	123_A	0.929	1.00
207_V	268_L	0.926	1.00
376_Y	443_I	0.926	1.00
456_L	468_H	0.925	1.00
191_M	194_E	0.923	1.00
120_E	130_A	0.923	1.00
520_C	548_P	0.920	1.00
129_M	142_V	0.919	1.00
8_D	12_Y	0.919	1.00
35_S	490_Y	0.918	1.00
453_I	518_L	0.915	1.00
229_L	335_E	0.914	1.00
207_V	274_V	0.913	1.00
55_S	97_I	0.913	1.00
347_E	351_D	0.910	1.00
467_I	551_V	0.908	1.00
471_V	555_L	0.906	1.00
351_D	354_Q	0.906	1.00
382_A	535_F	0.904	1.00
220_A	224_Q	0.904	1.00
187_A	328_L	0.902	1.00
37_M	43_I	0.901	1.00
374_R	531_I	0.897	1.00
459_G	468_H	0.897	1.00
534_A	538_A	0.897	1.00
349_V	352_C	0.895	1.00
63_R	95_I	0.889	1.00
457_A	518_L	0.889	1.00
6_A	136_A	0.886	1.00
198_E	201_I	0.886	1.00
467_I	539_K	0.884	1.00
408_K	411_H	0.883	1.00
466_Y	548_P	0.882	1.00
375_V	471_V	0.880	1.00
293_T	296_R	0.880	1.00
13_V	17_E	0.879	1.00
463_N	546_R	0.876	1.00
68_N	151_R	0.876	1.00
94_S	154_R	0.876	1.00
430_G	434_A	0.875	1.00
187_A	324_A	0.874	1.00
449_F	550_V	0.872	1.00
222_L	326_L	0.867	1.00
145_Q	149_L	0.866	1.00
450_Q	453_I	0.865	1.00
301_I	318_I	0.861	1.00
459_G	548_P	0.861	1.00
71_V	98_L	0.859	1.00
121_A	125_P	0.858	1.00
81_T	88_Y	0.857	1.00
382_A	539_K	0.857	1.00
60_G	427_A	0.855	1.00
196_A	199_M	0.855	1.00
190_R	194_E	0.855	1.00
354_Q	357_R	0.851	1.00
198_E	336_M	0.848	1.00
516_E	522_A	0.846	1.00
35_S	38_R	0.845	1.00
386_D	408_K	0.845	1.00
400_A	443_I	0.845	1.00
199_M	299_V	0.845	1.00
530_D	534_A	0.844	1.00
129_M	146_A	0.842	1.00
215_I	243_C	0.842	1.00
523_I	541_L	0.839	1.00
447_F	476_L	0.835	1.00
247_D	385_R	0.833	1.00
162_L	167_Q	0.832	1.00
120_E	132_T	0.832	1.00
376_Y	471_V	0.831	1.00
85_T	420_P	0.830	1.00
503_E	506_G	0.829	1.00
98_L	151_R	0.828	1.00
21_T	61_Y	0.827	1.00
84_I	123_A	0.826	1.00
150_M	158_V	0.825	1.00
136_A	140_P	0.825	1.00
387_V	441_V	0.823	1.00
534_A	537_Q	0.818	1.00
65_T	68_N	0.818	1.00
443_I	471_V	0.816	1.00
196_A	273_M	0.815	1.00
210_A	236_P	0.815	1.00
13_V	16_K	0.813	1.00
246_D	251_M	0.810	1.00
188_A	193_I	0.808	1.00
205_R	272_D	0.808	1.00
32_P	168_V	0.808	1.00
461_Q	507_Y	0.806	1.00
5_R	36_A	0.806	1.00
510_D	516_E	0.805	1.00
219_A	222_L	0.803	1.00
308_I	317_G	0.802	1.00
460_A	548_P	0.800	1.00
474_A	557_R	0.800	1.00
19_I	147_F	0.799	1.00
230_T	333_A	0.798	1.00
26_P	47_L	0.798	1.00
64_A	413_I	0.796	1.00
347_E	350_A	0.795	1.00
196_A	325_A	0.793	1.00
128_K	158_V	0.792	1.00
510_D	524_R	0.790	1.00
472_N	554_I	0.789	1.00
522_A	552_E	0.786	1.00
208_I	277_I	0.785	1.00
201_I	331_E	0.783	1.00
273_M	297_K	0.783	1.00
467_I	546_R	0.782	1.00
17_E	151_R	0.781	1.00
20_T	61_Y	0.781	1.00
441_V	469_V	0.781	1.00
210_A	234_V	0.781	1.00
64_A	434_A	0.777	1.00
212_G	239_M	0.776	1.00
255_V	268_L	0.773	1.00
75_T	115_Q	0.772	1.00
429_L	464_I	0.771	1.00
378_E	531_I	0.770	1.00
14_L	71_V	0.769	1.00
129_M	145_Q	0.765	1.00
376_Y	404_L	0.765	1.00
62_T	97_I	0.764	1.00
396_S	448_D	0.764	1.00
87_L	126_V	0.764	1.00
48_A	53_G	0.761	1.00
305_P	319_V	0.759	1.00
380_N	407_F	0.758	1.00
56_H	420_P	0.758	1.00
425_I	468_H	0.756	1.00
529_E	533_P	0.756	1.00
129_M	158_V	0.755	1.00
214_V	243_C	0.754	1.00
61_Y	68_N	0.753	1.00
275_F	301_I	0.750	1.00
132_T	161_D	0.750	1.00
73_L	100_I	0.749	1.00
30_I	34_Y	0.749	1.00
201_I	332_V	0.748	1.00
74_G	101_T	0.747	1.00
148_H	152_S	0.746	1.00
238_L	401_A	0.746	1.00
450_Q	509_V	0.745	1.00
128_K	149_L	0.744	1.00
52_E	82_D	0.742	1.00
370_V	528_P	0.740	1.00
193_I	328_L	0.738	1.00
188_A	324_A	0.737	1.00
345_R	352_C	0.737	1.00
88_Y	126_V	0.736	1.00
25_V	83_M	0.734	1.00
391_T	414_N	0.734	1.00
443_I	469_V	0.733	1.00
62_T	95_I	0.731	1.00
184_Y	187_A	0.730	1.00
244_I	251_M	0.730	1.00
245_P	407_F	0.729	1.00
425_I	444_S	0.728	1.00
23_F	57_M	0.727	1.00
383_F	387_V	0.727	1.00
219_A	323_K	0.724	1.00
391_T	412_W	0.723	1.00
192_Q	196_A	0.723	1.00
468_H	520_C	0.722	1.00
236_P	246_D	0.721	1.00
15_E	20_T	0.721	1.00
348_W	351_D	0.721	1.00
206_P	232_V	0.720	1.00
30_I	73_L	0.718	1.00
218_D	410_R	0.717	1.00
195_K	316_L	0.717	1.00
199_M	202_Q	0.717	1.00
328_L	332_V	0.714	1.00
38_R	490_Y	0.714	1.00
22_A	73_L	0.711	1.00
327_T	331_E	0.710	1.00
428_A	466_Y	0.709	1.00
392_T	424_T	0.709	1.00
101_T	161_D	0.708	1.00
185_K	321_D	0.708	1.00
459_G	464_I	0.707	1.00
95_I	423_W	0.705	1.00
439_N	465_P	0.704	1.00
449_F	511_H	0.703	1.00
300_H	314_P	0.703	1.00
256_G	259_T	0.701	1.00
33_F	167_Q	0.700	1.00
391_T	400_A	0.696	1.00
450_Q	511_H	0.694	1.00
81_T	84_I	0.693	1.00
480_R	484_R	0.691	0.99
390_V	413_I	0.691	0.99
469_V	531_I	0.690	0.99
20_T	42_G	0.689	0.99
35_S	39_K	0.688	0.99
441_V	467_I	0.687	0.99
345_R	348_W	0.686	0.99
375_V	469_V	0.685	0.99
480_R	505_N	0.684	0.99
55_S	99_C	0.682	0.99
442_A	448_D	0.680	0.99
388_C	438_R	0.680	0.99
266_A	269_L	0.680	0.99
206_P	273_M	0.678	0.99
192_Q	318_I	0.677	0.99
213_G	302_D	0.677	0.99
136_A	171_I	0.677	0.99
90_A	97_I	0.677	0.99
106_R	163_P	0.675	0.99
60_G	430_G	0.675	0.99
229_L	333_A	0.674	0.99
106_R	134_R	0.673	0.99
74_G	80_G	0.673	0.99
140_P	144_Q	0.672	0.99
209_V	276_G	0.672	0.99
208_I	234_V	0.672	0.99
49_R	461_Q	0.672	0.99
220_A	409_D	0.672	0.99
200_L	230_T	0.671	0.99
525_V	551_V	0.668	0.99
475_Y	480_R	0.668	0.99
510_D	552_E	0.667	0.99
217_A	321_D	0.666	0.99
460_A	519_G	0.666	0.99
425_I	455_E	0.665	0.99
176_D	179_E	0.665	0.99
120_E	124_K	0.663	0.99
327_T	330_V	0.661	0.99
370_V	527_K	0.660	0.99
187_A	190_R	0.659	0.99
188_A	320_S	0.659	0.99
390_V	431_V	0.659	0.99
82_D	85_T	0.659	0.99
136_A	166_V	0.657	0.99
145_Q	148_H	0.656	0.99
33_F	73_L	0.655	0.99
331_E	334_Q	0.655	0.99
91_S	128_K	0.655	0.99
520_C	547_V	0.654	0.99
325_A	328_L	0.654	0.99
355_R	358_T	0.654	0.99
6_A	9_A	0.653	0.99
426_P	455_E	0.651	0.99
142_V	145_Q	0.651	0.99
182_P	187_A	0.648	0.99
465_P	548_P	0.648	0.99
133_V	163_P	0.647	0.99
32_P	167_Q	0.645	0.99
230_T	250_L	0.643	0.99
245_P	248_H	0.642	0.99
227_A	230_T	0.641	0.99
460_A	507_Y	0.638	0.99
92_A	418_A	0.636	0.99
322_A	327_T	0.633	0.99
81_T	117_V	0.632	0.99
209_V	237_T	0.631	0.99
330_V	334_Q	0.631	0.99
193_I	329_L	0.630	0.99
149_L	154_R	0.630	0.99
123_A	159_L	0.628	0.99
30_I	102_G	0.627	0.99
390_V	424_T	0.626	0.99
114_F	419_G	0.625	0.99
276_G	298_I	0.625	0.99
509_V	517_G	0.622	0.99
56_H	89_S	0.622	0.99
225_Q	331_E	0.621	0.99
241_W	406_V	0.620	0.99
231_S	249_E	0.619	0.99
527_K	533_P	0.618	0.99
96_P	150_M	0.615	0.99
302_D	307_Q	0.615	0.99
444_S	452_L	0.613	0.99
534_A	549_V	0.612	0.99
387_V	438_R	0.612	0.99
261_H	361_R	0.611	0.99
413_I	423_W	0.611	0.99
50_H	82_D	0.610	0.99
386_D	439_N	0.609	0.99
546_R	549_V	0.609	0.99
11_M	41_G	0.609	0.99
22_A	43_I	0.609	0.99
356_K	359_L	0.609	0.99
429_L	458_V	0.608	0.99
467_I	547_V	0.608	0.99
21_T	68_N	0.607	0.99
433_A	462_F	0.607	0.99
25_V	476_L	0.607	0.99
103_Q	109_L	0.605	0.99
15_E	43_I	0.605	0.99
146_A	160_V	0.604	0.99
222_L	226_F	0.604	0.99
193_I	318_I	0.604	0.99
98_L	160_V	0.602	0.99
88_Y	117_V	0.602	0.99
428_A	440_V	0.601	0.99
368_V	528_P	0.600	0.99
332_V	336_M	0.599	0.99
101_T	119_I	0.598	0.99
204_E	347_E	0.598	0.99
182_P	185_K	0.597	0.99
209_V	274_V	0.597	0.99
223_L	227_A	0.596	0.98
61_Y	70_G	0.594	0.98
265_N	269_L	0.594	0.98
444_S	468_H	0.593	0.98
110_H	116_A	0.593	0.98
480_R	557_R	0.593	0.98
204_E	272_D	0.591	0.98
373_Q	559_T	0.590	0.98
453_I	517_G	0.590	0.98
138_L	142_V	0.589	0.98
308_I	314_P	0.588	0.98
242_G	246_D	0.587	0.98
383_F	404_L	0.586	0.98
128_K	154_R	0.586	0.98
209_V	279_N	0.585	0.98
131_V	158_V	0.584	0.98
425_I	459_G	0.584	0.98
375_V	531_I	0.583	0.98
431_V	440_V	0.582	0.98
103_Q	132_T	0.582	0.98
183_V	187_A	0.581	0.98
391_T	424_T	0.581	0.98
44_R	436_P	0.581	0.98
325_A	329_L	0.580	0.98
16_K	177_M	0.580	0.98
450_Q	454_E	0.579	0.98
224_Q	408_K	0.579	0.98
396_S	471_V	0.579	0.98
57_M	433_A	0.579	0.98
100_I	160_V	0.577	0.98
374_R	532_A	0.576	0.98
379_M	469_V	0.575	0.98
28_A	75_T	0.574	0.98
201_I	204_E	0.574	0.98
106_R	166_V	0.574	0.98
368_V	527_K	0.573	0.98
147_F	151_R	0.573	0.98
165_D	169_A	0.572	0.98
106_R	135_E	0.570	0.98
346_K	349_V	0.570	0.98
13_V	140_P	0.569	0.98
224_Q	227_A	0.568	0.98
49_R	457_A	0.567	0.98
83_M	101_T	0.566	0.98
27_G	75_T	0.565	0.98
523_I	533_P	0.564	0.98
352_C	359_L	0.563	0.98
369_P	556_E	0.562	0.98
242_G	411_H	0.562	0.98
215_I	410_R	0.562	0.98
449_F	468_H	0.562	0.98
221_A	228_E	0.561	0.98
119_I	159_L	0.561	0.98
64_A	388_C	0.560	0.98
484_R	489_D	0.560	0.98
219_A	322_A	0.559	0.98
98_L	158_V	0.557	0.98
239_M	416_G	0.556	0.98
69_I	150_M	0.554	0.98
63_R	93_D	0.553	0.98
100_I	143_L	0.553	0.98
460_A	463_N	0.552	0.98
299_V	316_L	0.552	0.98
89_S	93_D	0.551	0.98
252_A	264_G	0.548	0.97
463_N	547_V	0.547	0.97
83_M	86_A	0.547	0.97
9_A	173_F	0.547	0.97
388_C	413_I	0.547	0.97
479_I	483_Q	0.547	0.97
348_W	356_K	0.547	0.97
59_E	427_A	0.546	0.97
537_Q	549_V	0.545	0.97
457_A	509_V	0.545	0.97
509_V	514_V	0.544	0.97
55_S	87_L	0.543	0.97
44_R	433_A	0.543	0.97
154_R	304_E	0.542	0.97
392_T	442_A	0.542	0.97
444_S	448_D	0.542	0.97
509_V	518_L	0.542	0.97
215_I	220_A	0.541	0.97
372_P	399_A	0.541	0.97
510_D	517_G	0.540	0.97
136_A	139_V	0.540	0.97
11_M	37_M	0.540	0.97
19_I	69_I	0.540	0.97
207_V	267_T	0.539	0.97
525_V	533_P	0.538	0.97
333_A	336_M	0.538	0.97
189_S	324_A	0.538	0.97
149_L	152_S	0.537	0.97
71_V	100_I	0.537	0.97
236_P	241_W	0.537	0.97
46_I	458_V	0.536	0.97
400_A	412_W	0.536	0.97
363_T	377_E	0.535	0.97
468_H	550_V	0.534	0.97
190_R	331_E	0.534	0.97
484_R	490_Y	0.534	0.97
61_Y	65_T	0.534	0.97
535_F	539_K	0.533	0.97
133_V	162_L	0.533	0.97
521_K	546_R	0.533	0.97
13_V	147_F	0.532	0.97
16_K	173_F	0.532	0.97
20_T	65_T	0.531	0.97
390_V	427_A	0.530	0.97
250_L	349_V	0.530	0.97
458_V	464_I	0.530	0.97
128_K	152_S	0.530	0.97
191_M	195_K	0.530	0.97
366_D	529_E	0.530	0.97
528_P	532_A	0.529	0.97
6_A	169_A	0.528	0.97
408_K	438_R	0.528	0.97
426_P	452_L	0.526	0.97
304_E	307_Q	0.525	0.97
349_V	356_K	0.525	0.97
25_V	48_A	0.525	0.97
29_A	76_S	0.524	0.97
28_A	482_S	0.524	0.97
137_A	172_E	0.524	0.97
62_T	70_G	0.524	0.97
421_L	479_I	0.522	0.97
425_I	453_I	0.521	0.97
376_Y	400_A	0.521	0.97
62_T	69_I	0.520	0.96
148_H	151_R	0.519	0.96
516_E	523_I	0.519	0.96
140_P	143_L	0.517	0.96
11_M	40_H	0.515	0.96
71_V	147_F	0.514	0.96
357_R	361_R	0.514	0.96
52_E	452_L	0.514	0.96
23_F	433_A	0.514	0.96
35_S	483_Q	0.512	0.96
28_A	479_I	0.511	0.96
91_S	156_G	0.511	0.96
332_V	335_E	0.510	0.96
395_L	478_L	0.510	0.96
212_G	280_R	0.508	0.96
54_A	72_C	0.506	0.96
456_L	459_G	0.505	0.96
91_S	127_S	0.505	0.96
56_H	86_A	0.504	0.96
362_K	366_D	0.504	0.96
235_I	255_V	0.503	0.96
527_K	531_I	0.503	0.96
110_H	113_D	0.503	0.96
456_L	460_A	0.503	0.96
124_K	130_A	0.502	0.96
469_V	538_A	0.502	0.96
184_Y	189_S	0.501	0.96
307_Q	310_R	0.501	0.96
75_T	80_G	0.501	0.96
214_V	219_A	0.501	0.96
391_T	394_G	0.500	0.96
472_N	511_H	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2panA	3	0.9882	100	0.18	Contact Map
1ozhA	4	0.9207	100	0.194	Contact Map
1ybhA	4	0.9511	100	0.197	Contact Map
1t9bA	2	0.9595	100	0.198	Contact Map
4rjjA	5	0.9325	100	0.201	Contact Map
2pgnA	4	0.9427	100	0.203	Contact Map
2ihtA	4	0.9089	100	0.205	Contact Map
2uz1A	4	0.9174	100	0.207	Contact Map
3eyaA	5	0.887	100	0.212	Contact Map
2x7jA	4	0.9376	100	0.218	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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