GREMLIN Database
EUTN - Ethanolamine utilization protein EutN
UniProt: P0AEJ8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14186
Length: 95 (86)
Sequences: 526 (380)
Seq/√Len: 40.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_L82_V4.4951.00
42_V56_L3.2941.00
18_G73_P2.7831.00
54_W82_V2.4791.00
58_V62_S2.2441.00
27_V57_L2.1860.99
31_D35_N2.0340.99
48_G53_E1.9130.99
43_A78_V1.8880.98
61_S64_R1.8830.98
42_V75_D1.7120.97
27_V43_A1.6930.97
22_D44_I1.6920.97
2_K59_S1.6590.97
65_Q70_E1.6470.96
25_L78_V1.6450.96
15_R21_H1.5590.95
25_L51_T1.5190.94
28_E40_C1.4970.94
7_T10_I1.4910.94
53_E58_V1.4560.93
4_A41_A1.4120.92
3_L10_I1.4080.92
2_K29_M1.3990.91
34_G54_W1.3750.91
58_V77_C1.3380.89
23_K47_I1.3300.89
57_L76_L1.3190.89
6_V27_V1.2540.86
30_I54_W1.2380.85
27_V78_V1.2370.85
15_R76_L1.2210.85
49_A81_I1.1990.83
60_G64_R1.1840.83
44_I74_V1.1790.82
11_V20_A1.1730.82
66_A69_S1.1320.80
6_V43_A1.1080.78
29_M41_A1.0850.77
16_H66_A1.0720.76
4_A14_V1.0700.76
5_V36_P1.0590.75
48_G75_D1.0440.74
11_V22_D1.0400.74
2_K41_A1.0380.73
21_H47_I1.0170.72
12_C20_A1.0080.71
11_V44_I1.0030.71
3_L42_V0.9950.70
53_E72_S0.9730.69
17_H86_V0.9670.68
30_I37_D0.9470.66
43_A56_L0.9370.66
7_T36_P0.9090.63
71_T77_C0.9010.62
22_D67_H0.8940.62
69_S77_C0.8880.61
47_I77_C0.8670.59
10_I37_D0.8640.59
68_K79_I0.8350.57
12_C64_R0.8290.56
16_H46_N0.8280.56
29_M39_Q0.8260.56
19_L24_L0.8140.55
63_A75_D0.8110.54
55_V64_R0.8030.54
53_E69_S0.7820.52
26_M30_I0.7810.52
4_A26_M0.7680.50
7_T37_D0.7670.50
63_A73_P0.7630.50
59_S76_L0.7580.49
14_V21_H0.7520.49
17_H74_V0.7440.48
27_V56_L0.7380.48
2_K14_V0.7320.47
52_G86_V0.7200.46
27_V80_G0.7190.46
5_V27_V0.7130.45
76_L80_G0.7080.45
41_A76_L0.7030.44
9_Q14_V0.6860.43
4_A27_V0.6770.42
16_H27_V0.6740.42
35_N39_Q0.6520.40
7_T16_H0.6440.39
20_A51_T0.6430.39
14_V17_H0.6320.38
60_G63_A0.6290.38
5_V51_T0.6220.37
19_L48_G0.6210.37
48_G81_I0.6190.37
28_E38_G0.6120.36
22_D78_V0.5860.34
24_L42_V0.5860.34
18_G46_N0.5850.34
69_S80_G0.5820.34
33_Q79_I0.5810.34
2_K37_D0.5800.34
74_V77_C0.5800.34
24_L32_P0.5720.33
8_G31_D0.5680.33
8_G85_V0.5630.32
11_V54_W0.5620.32
31_D54_W0.5580.32
34_G86_V0.5550.32
56_L61_S0.5540.31
37_D85_V0.5510.31
42_V48_G0.5510.31
18_G21_H0.5490.31
65_Q69_S0.5440.31
5_V54_W0.5410.30
41_A80_G0.5380.30
26_M78_V0.5360.30
14_V19_L0.5290.30
10_I41_A0.5280.29
47_I78_V0.5250.29
8_G11_V0.5220.29
56_L64_R0.5210.29
22_D77_C0.5180.29
33_Q38_G0.5150.28
19_L61_S0.5140.28
29_M47_I0.5130.28
25_L40_C0.5120.28
11_V14_V0.5110.28
44_I52_G0.5070.28
3_L20_A0.5050.28
37_D69_S0.5020.27
18_G68_K0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qw7A 3 1 100 0.084 Contact Map
4n8fA 3 1 100 0.086 Contact Map
4jw0B 3 1 100 0.087 Contact Map
2hd3A 3 1 100 0.089 Contact Map
4i7aA 3 0.8947 100 0.144 Contact Map
2rcfA 3 0.8632 100 0.201 Contact Map
2o5aA 2 0.6632 6.7 0.934 Contact Map
4wcwA 2 0.7053 5.6 0.936 Contact Map
2id1A 1 0.7158 5.1 0.938 Contact Map
1w2wB 2 0.7474 4.9 0.938 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0054 seconds.