BARA - ECOLI - GREMLIN Contacts

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BARA - Signal transduction histidine-protein kinase BarA

UniProt:	P0AEC5	Sequences: MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11367
Length:	918 (763)
Sequences:	1331 (1104)
Seq/√Len:	40.0

ECOLI - BARA TORS RCSC RCSD ARCB EVGS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
695_E	712_F	10.029	1.00
717_M	729_A	5.683	1.00
674_D	680_L	5.224	1.00
699_S	723_D	5.078	1.00
366_F	404_G	4.970	1.00
704_V	729_A	4.689	1.00
501_S	513_W	4.641	1.00
701_H	705_E	4.586	1.00
697_C	706_R	4.470	1.00
315_T	334_I	4.417	1.00
461_Q	502_F	4.410	1.00
364_I	406_P	4.270	1.00
698_D	702_Q	3.781	1.00
456_I	460_D	3.683	1.00
404_G	496_M	3.587	1.00
741_Q	765_S	3.504	1.00
447_V	514_F	3.448	1.00
321_T	327_Q	3.441	1.00
766_D	784_Y	3.353	1.00
680_L	696_L	3.352	1.00
258_I	262_T	3.322	1.00
725_D	728_R	3.305	1.00
362_E	404_G	3.265	1.00
757_E	761_G	3.208	1.00
636_P	642_L	3.185	1.00
272_M	276_N	3.157	1.00
672_A	683_I	3.144	1.00
353_K	482_T	3.042	1.00
636_P	646_L	3.041	1.00
417_V	431_I	3.032	1.00
609_L	613_L	2.987	1.00
680_L	698_D	2.961	1.00
323_L	327_Q	2.945	1.00
424_T	452_T	2.945	1.00
310_G	337_S	2.857	1.00
683_I	747_V	2.838	1.00
730_C	764_M	2.827	1.00
669_T	693_H	2.826	1.00
686_L	717_M	2.814	1.00
668_M	785_K	2.783	1.00
472_D	477_R	2.772	1.00
719_I	727_I	2.741	1.00
686_L	729_A	2.707	1.00
673_V	697_C	2.688	1.00
715_I	742_T	2.665	1.00
412_I	493_V	2.571	1.00
474_S	477_R	2.558	1.00
724_M	728_R	2.502	1.00
269_L	272_M	2.474	1.00
477_R	480_G	2.464	1.00
701_H	723_D	2.432	1.00
314_F	682_L	2.431	1.00
720_Q	750_H	2.430	1.00
493_V	514_F	2.408	1.00
609_L	612_A	2.353	1.00
457_P	460_D	2.346	1.00
289_A	293_K	2.339	1.00
737_P	741_Q	2.304	1.00
362_E	406_P	2.303	1.00
717_M	730_C	2.245	1.00
471_A	480_G	2.178	0.99
719_I	759_L	2.174	0.99
382_S	385_D	2.161	0.99
231_G	237_K	2.155	0.99
297_L	300_M	2.147	0.99
321_T	330_H	2.145	0.99
642_L	646_L	2.141	0.99
269_L	273_E	2.137	0.99
750_H	755_Q	2.124	0.99
241_N	244_A	2.121	0.99
316_R	773_E	2.107	0.99
312_I	338_A	2.104	0.99
273_E	276_N	2.084	0.99
475_I	480_G	2.065	0.99
754_G	757_E	2.064	0.99
505_Q	508_R	2.046	0.99
365_P	403_I	2.028	0.99
490_Q	494_N	2.009	0.99
683_I	717_M	1.987	0.99
258_I	261_A	1.971	0.99
674_D	696_L	1.967	0.99
674_D	750_H	1.967	0.99
404_G	518_L	1.962	0.99
720_Q	755_Q	1.949	0.99
308_L	314_F	1.940	0.99
205_P	236_L	1.918	0.99
534_L	561_L	1.918	0.99
300_M	321_T	1.912	0.98
362_E	366_F	1.911	0.98
672_A	694_V	1.909	0.98
231_G	234_D	1.892	0.98
673_V	683_I	1.890	0.98
233_L	240_I	1.887	0.98
482_T	767_Y	1.880	0.98
255_Q	262_T	1.875	0.98
759_L	764_M	1.857	0.98
457_P	506_P	1.831	0.98
756_K	766_D	1.823	0.98
59_G	64_N	1.799	0.98
367_P	400_D	1.791	0.98
312_I	315_T	1.791	0.98
732_L	735_Q	1.771	0.97
314_F	759_L	1.765	0.97
540_A	577_Y	1.747	0.97
707_A	742_T	1.742	0.97
412_I	514_F	1.738	0.97
448_Q	511_T	1.731	0.97
472_D	480_G	1.727	0.97
347_D	408_R	1.713	0.97
268_T	272_M	1.706	0.97
706_R	712_F	1.698	0.97
300_M	348_V	1.683	0.97
300_M	304_L	1.679	0.97
240_I	243_M	1.673	0.96
730_C	744_V	1.667	0.96
333_T	337_S	1.667	0.96
280_D	283_K	1.664	0.96
320_K	689_D	1.647	0.96
766_D	783_R	1.639	0.96
729_A	733_I	1.624	0.96
408_R	492_L	1.620	0.96
213_V	243_M	1.618	0.96
15_L	18_T	1.616	0.96
254_M	261_A	1.603	0.95
751_A	769_A	1.602	0.95
734_H	765_S	1.601	0.95
324_T	327_Q	1.597	0.95
255_Q	261_A	1.571	0.95
751_A	767_Y	1.569	0.95
269_L	276_N	1.569	0.95
719_I	764_M	1.561	0.95
456_I	471_A	1.556	0.95
329_D	681_K	1.555	0.95
704_V	707_A	1.554	0.95
683_I	729_A	1.547	0.94
298_A	477_R	1.541	0.94
635_K	642_L	1.540	0.94
282_A	286_A	1.519	0.94
537_K	578_D	1.519	0.94
748_T	759_L	1.516	0.94
443_V	517_N	1.515	0.94
276_N	279_L	1.514	0.94
331_L	676_N	1.497	0.93
686_L	774_E	1.495	0.93
263_S	268_T	1.488	0.93
669_T	713_D	1.484	0.93
474_S	480_G	1.478	0.93
538_R	562_E	1.475	0.93
542_V	572_L	1.460	0.93
728_R	732_L	1.448	0.92
254_M	258_I	1.446	0.92
294_S	512_F	1.440	0.92
460_D	471_A	1.438	0.92
668_M	713_D	1.434	0.92
479_H	757_E	1.431	0.92
310_G	678_A	1.428	0.92
750_H	759_L	1.427	0.92
299_N	720_Q	1.424	0.92
670_V	692_Q	1.422	0.92
673_V	699_S	1.418	0.91
717_M	720_Q	1.417	0.91
433_V	447_V	1.415	0.91
304_L	308_L	1.414	0.91
673_V	703_A	1.413	0.91
717_M	746_A	1.413	0.91
283_K	287_Q	1.412	0.91
754_G	767_Y	1.412	0.91
717_M	755_Q	1.405	0.91
447_V	518_L	1.404	0.91
714_L	785_K	1.400	0.91
155_N	158_G	1.399	0.91
476_S	480_G	1.399	0.91
444_Q	517_N	1.397	0.91
345_I	354_L	1.391	0.91
216_I	243_M	1.387	0.90
470_Q	477_R	1.383	0.90
674_D	699_S	1.379	0.90
237_K	240_I	1.372	0.90
229_M	234_D	1.369	0.90
682_L	764_M	1.368	0.90
717_M	747_V	1.364	0.90
418_G	449_I	1.359	0.90
358_K	720_Q	1.357	0.89
366_F	403_I	1.353	0.89
145_S	149_D	1.352	0.89
472_D	720_Q	1.348	0.89
383_S	421_I	1.343	0.89
751_A	754_G	1.343	0.89
300_M	674_D	1.341	0.89
376_V	431_I	1.338	0.89
446_E	515_H	1.337	0.89
669_T	695_E	1.337	0.89
344_I	407_L	1.331	0.89
412_I	497_G	1.329	0.88
699_S	724_M	1.325	0.88
475_I	479_H	1.322	0.88
283_K	286_A	1.320	0.88
432_L	450_R	1.313	0.88
383_S	418_G	1.309	0.88
209_M	213_V	1.285	0.87
715_I	729_A	1.284	0.87
268_T	276_N	1.282	0.87
355_E	413_I	1.272	0.86
232_E	747_V	1.272	0.86
715_I	744_V	1.269	0.86
318_T	327_Q	1.268	0.86
255_Q	258_I	1.268	0.86
612_A	615_C	1.267	0.86
690_M	774_E	1.263	0.86
719_I	754_G	1.260	0.86
435_K	445_I	1.257	0.85
289_A	292_I	1.257	0.85
456_I	502_F	1.255	0.85
309_N	746_A	1.249	0.85
45_G	52_L	1.241	0.85
633_L	636_P	1.231	0.84
354_L	357_G	1.231	0.84
237_K	241_N	1.230	0.84
372_L	431_I	1.230	0.84
727_I	758_K	1.221	0.84
379_L	414_T	1.220	0.84
316_R	774_E	1.213	0.83
363_S	519_D	1.211	0.83
225_V	240_I	1.209	0.83
460_D	463_R	1.208	0.83
380_A	384_H	1.203	0.83
275_Q	279_L	1.201	0.83
636_P	643_L	1.193	0.82
728_R	731_E	1.191	0.82
611_L	614_P	1.189	0.82
310_G	719_I	1.188	0.82
457_P	471_A	1.188	0.82
704_V	724_M	1.184	0.82
206_I	344_I	1.176	0.81
348_V	752_M	1.174	0.81
695_E	706_R	1.174	0.81
503_H	511_T	1.170	0.81
315_T	319_L	1.170	0.81
470_Q	480_G	1.169	0.81
311_V	410_Q	1.169	0.81
733_I	746_A	1.168	0.81
737_P	765_S	1.163	0.81
304_L	354_L	1.162	0.81
408_R	411_Q	1.160	0.80
347_D	357_G	1.159	0.80
475_I	747_V	1.158	0.80
337_S	678_A	1.154	0.80
297_L	355_E	1.149	0.80
308_L	335_E	1.147	0.80
731_E	762_A	1.145	0.80
368_L	445_I	1.144	0.80
471_A	475_I	1.142	0.79
413_I	674_D	1.142	0.79
373_D	767_Y	1.136	0.79
583_G	587_T	1.136	0.79
348_V	353_K	1.135	0.79
432_L	448_Q	1.134	0.79
389_E	635_K	1.131	0.79
755_Q	767_Y	1.130	0.79
716_L	777_L	1.127	0.79
129_M	134_P	1.127	0.79
311_V	351_F	1.127	0.79
688_E	694_V	1.126	0.78
737_P	740_Q	1.124	0.78
310_G	767_Y	1.121	0.78
333_T	375_V	1.121	0.78
229_M	237_K	1.120	0.78
364_I	471_A	1.117	0.78
326_T	685_A	1.116	0.78
224_R	244_A	1.115	0.78
699_S	729_A	1.112	0.78
308_L	720_Q	1.112	0.78
632_C	636_P	1.107	0.77
30_V	34_Y	1.106	0.77
382_S	683_I	1.102	0.77
407_L	673_V	1.102	0.77
708_K	736_L	1.101	0.77
224_R	241_N	1.098	0.77
707_A	715_I	1.098	0.77
673_V	756_K	1.097	0.77
452_T	456_I	1.096	0.77
240_I	244_A	1.094	0.76
606_T	609_L	1.092	0.76
546_S	731_E	1.091	0.76
330_H	717_M	1.088	0.76
560_P	563_V	1.087	0.76
300_M	353_K	1.087	0.76
297_L	304_L	1.087	0.76
202_V	205_P	1.085	0.76
374_E	410_Q	1.085	0.76
383_S	387_G	1.084	0.76
231_G	682_L	1.083	0.76
272_M	275_Q	1.075	0.75
290_A	293_K	1.074	0.75
383_S	388_L	1.071	0.75
362_E	772_I	1.070	0.75
413_I	417_V	1.067	0.75
320_K	774_E	1.067	0.75
352_S	484_L	1.065	0.74
268_T	273_E	1.065	0.74
279_L	282_A	1.065	0.74
68_I	72_I	1.062	0.74
330_H	345_I	1.060	0.74
684_G	688_E	1.059	0.74
329_D	333_T	1.058	0.74
130_I	134_P	1.057	0.74
291_R	295_E	1.053	0.74
714_L	784_Y	1.051	0.73
467_A	720_Q	1.044	0.73
730_C	747_V	1.044	0.73
337_S	737_P	1.044	0.73
449_I	502_F	1.043	0.73
45_G	56_T	1.043	0.73
312_I	406_P	1.042	0.73
615_C	618_Q	1.041	0.73
219_G	222_D	1.040	0.73
746_A	764_M	1.038	0.73
213_V	240_I	1.037	0.72
345_I	348_V	1.036	0.72
56_T	59_G	1.035	0.72
146_P	149_D	1.035	0.72
56_T	158_G	1.034	0.72
434_E	446_E	1.033	0.72
286_A	748_T	1.032	0.72
727_I	759_L	1.031	0.72
312_I	334_I	1.030	0.72
310_G	764_M	1.029	0.72
49_I	53_A	1.027	0.72
502_F	512_F	1.027	0.72
14_I	22_G	1.022	0.71
540_A	566_S	1.021	0.71
379_L	421_I	1.020	0.71
267_E	270_E	1.020	0.71
330_H	686_L	1.018	0.71
23_L	26_S	1.014	0.71
308_L	345_I	1.014	0.71
402_V	694_V	1.008	0.70
89_Y	93_N	1.007	0.70
87_S	95_L	1.004	0.70
356_A	784_Y	1.003	0.70
257_N	674_D	1.002	0.70
14_I	17_P	1.002	0.70
695_E	713_D	1.002	0.70
279_L	489_T	1.000	0.70
314_F	719_I	0.999	0.70
353_K	470_Q	0.999	0.70
746_A	767_Y	0.997	0.69
233_L	237_K	0.995	0.69
337_S	767_Y	0.994	0.69
59_G	63_Q	0.992	0.69
147_S	150_A	0.992	0.69
699_S	732_L	0.987	0.69
707_A	717_M	0.987	0.69
423_F	480_G	0.985	0.68
379_L	417_V	0.980	0.68
48_I	53_A	0.975	0.68
374_E	673_V	0.974	0.68
477_R	725_D	0.972	0.67
270_E	273_E	0.969	0.67
422_K	481_G	0.967	0.67
312_I	404_G	0.966	0.67
737_P	747_V	0.964	0.67
88_V	93_N	0.964	0.67
466_Q	487_V	0.963	0.67
308_L	338_A	0.962	0.67
388_L	769_A	0.961	0.67
361_L	496_M	0.961	0.67
228_F	237_K	0.961	0.67
375_V	417_V	0.960	0.66
294_S	355_E	0.960	0.66
352_S	489_T	0.959	0.66
470_Q	479_H	0.959	0.66
514_F	517_N	0.956	0.66
475_I	728_R	0.955	0.66
609_L	615_C	0.955	0.66
158_G	162_L	0.951	0.66
310_G	699_S	0.947	0.65
504_S	507_N	0.947	0.65
300_M	344_I	0.946	0.65
333_T	767_Y	0.946	0.65
423_F	470_Q	0.944	0.65
697_C	702_Q	0.943	0.65
71_L	75_L	0.943	0.65
446_E	513_W	0.942	0.65
330_H	488_I	0.942	0.65
303_E	470_Q	0.941	0.65
250_Y	262_T	0.939	0.65
288_E	487_V	0.939	0.65
450_R	511_T	0.937	0.65
423_F	481_G	0.935	0.64
549_A	565_Y	0.934	0.64
634_L	646_L	0.931	0.64
344_I	482_T	0.930	0.64
344_I	464_L	0.930	0.64
409_L	516_I	0.930	0.64
72_I	413_I	0.929	0.64
707_A	744_V	0.929	0.64
719_I	746_A	0.928	0.64
337_S	690_M	0.928	0.64
243_M	246_S	0.927	0.64
89_Y	95_L	0.926	0.64
53_A	59_G	0.926	0.64
345_I	764_M	0.924	0.63
263_S	270_E	0.924	0.63
391_T	430_D	0.923	0.63
720_Q	727_I	0.919	0.63
719_I	737_P	0.919	0.63
729_A	755_Q	0.918	0.63
488_I	495_E	0.918	0.63
566_S	572_L	0.917	0.63
539_L	556_L	0.917	0.63
679_N	746_A	0.916	0.63
308_L	333_T	0.915	0.63
311_V	345_I	0.914	0.63
310_G	747_V	0.914	0.63
188_I	192_L	0.912	0.62
687_L	777_L	0.912	0.62
232_E	236_L	0.911	0.62
607_D	611_L	0.910	0.62
243_M	247_L	0.910	0.62
297_L	752_M	0.909	0.62
330_H	334_I	0.908	0.62
318_T	321_T	0.907	0.62
684_G	696_L	0.907	0.62
64_N	158_G	0.907	0.62
538_R	577_Y	0.907	0.62
716_L	729_A	0.907	0.62
299_N	330_H	0.906	0.62
750_H	754_G	0.905	0.62
310_G	737_P	0.903	0.62
286_A	297_L	0.902	0.62
293_K	311_V	0.900	0.61
707_A	729_A	0.895	0.61
334_I	682_L	0.894	0.61
707_A	736_L	0.894	0.61
14_I	28_F	0.894	0.61
679_N	763_G	0.893	0.61
752_M	755_Q	0.891	0.61
294_S	346_N	0.889	0.60
304_L	327_Q	0.886	0.60
70_Q	75_L	0.886	0.60
368_L	379_L	0.885	0.60
442_K	517_N	0.884	0.60
609_L	616_H	0.884	0.60
540_A	572_L	0.883	0.60
315_T	727_I	0.882	0.60
61_S	64_N	0.882	0.60
333_T	681_K	0.880	0.60
541_Y	552_T	0.880	0.60
310_G	323_L	0.879	0.60
344_I	351_F	0.876	0.59
363_S	404_G	0.875	0.59
347_D	359_L	0.874	0.59
454_I	479_H	0.873	0.59
333_T	685_A	0.872	0.59
683_I	764_M	0.871	0.59
276_N	280_D	0.871	0.59
665_K	692_Q	0.871	0.59
304_L	502_F	0.870	0.59
53_A	56_T	0.870	0.59
404_G	409_L	0.870	0.59
82_I	100_N	0.869	0.59
438_L	520_L	0.869	0.59
399_P	443_V	0.869	0.59
429_I	738_H	0.868	0.59
552_T	745_I	0.868	0.59
471_A	477_R	0.868	0.59
299_N	774_E	0.867	0.59
318_T	323_L	0.863	0.58
229_M	233_L	0.861	0.58
398_V	445_I	0.859	0.58
717_M	774_E	0.858	0.58
768_L	781_L	0.858	0.58
419_N	422_K	0.857	0.58
538_R	578_D	0.857	0.58
470_Q	486_L	0.857	0.58
412_I	492_L	0.855	0.57
361_L	416_L	0.855	0.57
718_D	726_G	0.855	0.57
455_G	481_G	0.854	0.57
144_E	147_S	0.852	0.57
673_V	680_L	0.852	0.57
474_S	479_H	0.849	0.57
321_T	324_T	0.848	0.57
714_L	745_I	0.848	0.57
299_N	311_V	0.847	0.57
41_L	56_T	0.843	0.56
333_T	678_A	0.843	0.56
411_Q	492_L	0.843	0.56
456_I	461_Q	0.842	0.56
327_Q	474_S	0.839	0.56
59_G	62_L	0.839	0.56
686_L	707_A	0.837	0.56
683_I	716_L	0.837	0.56
18_T	25_L	0.837	0.56
330_H	729_A	0.836	0.56
606_T	610_M	0.834	0.56
388_L	425_E	0.833	0.55
236_L	243_M	0.833	0.55
686_L	720_Q	0.833	0.55
314_F	334_I	0.832	0.55
720_Q	756_K	0.831	0.55
695_E	710_M	0.831	0.55
257_N	261_A	0.830	0.55
58_Y	62_L	0.830	0.55
755_Q	759_L	0.830	0.55
704_V	732_L	0.829	0.55
611_L	615_C	0.828	0.55
464_L	773_E	0.828	0.55
670_V	781_L	0.827	0.55
394_I	398_V	0.826	0.55
423_F	477_R	0.826	0.55
672_A	687_L	0.825	0.55
53_A	60_M	0.825	0.55
413_I	447_V	0.825	0.55
500_I	746_A	0.825	0.55
351_F	500_I	0.823	0.55
614_P	618_Q	0.823	0.55
311_V	378_L	0.822	0.54
294_S	510_S	0.822	0.54
442_K	519_D	0.821	0.54
717_M	764_M	0.821	0.54
362_E	480_G	0.821	0.54
751_A	772_I	0.820	0.54
153_S	158_G	0.820	0.54
471_A	487_V	0.819	0.54
404_G	719_I	0.819	0.54
353_K	480_G	0.816	0.54
47_S	50_E	0.816	0.54
726_G	749_A	0.813	0.54
676_N	763_G	0.812	0.54
318_T	331_L	0.812	0.54
691_V	750_H	0.810	0.53
318_T	333_T	0.810	0.53
388_L	424_T	0.809	0.53
299_N	467_A	0.809	0.53
309_N	351_F	0.808	0.53
312_I	342_L	0.808	0.53
419_N	481_G	0.806	0.53
472_D	479_H	0.806	0.53
213_V	231_G	0.804	0.53
299_N	686_L	0.801	0.53
338_A	674_D	0.799	0.52
372_L	490_Q	0.797	0.52
345_I	752_M	0.796	0.52
48_I	56_T	0.796	0.52
685_A	766_D	0.795	0.52
755_Q	758_K	0.793	0.52
756_K	760_L	0.792	0.52
39_R	42_E	0.791	0.52
680_L	759_L	0.790	0.52
605_M	609_L	0.790	0.52
694_V	773_E	0.789	0.51
471_A	479_H	0.788	0.51
556_L	563_V	0.788	0.51
333_T	381_H	0.787	0.51
310_G	383_S	0.787	0.51
286_A	764_M	0.786	0.51
751_A	756_K	0.785	0.51
320_K	333_T	0.782	0.51
314_F	368_L	0.782	0.51
337_S	408_R	0.781	0.51
692_Q	713_D	0.781	0.51
404_G	727_I	0.781	0.51
725_D	734_H	0.781	0.51
311_V	323_L	0.779	0.51
131_L	134_P	0.778	0.50
315_T	414_T	0.778	0.50
409_L	518_L	0.778	0.50
361_L	404_G	0.777	0.50
303_E	423_F	0.777	0.50
280_D	284_K	0.775	0.50
310_G	373_D	0.775	0.50
751_A	760_L	0.774	0.50
234_D	237_K	0.774	0.50
747_V	768_L	0.774	0.50
236_L	362_E	0.774	0.50
393_N	432_L	0.774	0.50
348_V	502_F	0.773	0.50
215_R	490_Q	0.772	0.50
686_L	690_M	0.772	0.50
311_V	321_T	0.771	0.50
304_L	321_T	0.771	0.50
314_F	764_M	0.769	0.50
373_D	707_A	0.769	0.50
564_V	577_Y	0.768	0.50
712_F	764_M	0.767	0.49
309_N	767_Y	0.765	0.49
59_G	158_G	0.765	0.49
308_L	681_K	0.764	0.49
289_A	342_L	0.763	0.49
271_Q	274_I	0.763	0.49
580_M	583_G	0.763	0.49
492_L	496_M	0.760	0.49
423_F	479_H	0.760	0.49
445_I	489_T	0.759	0.49
701_H	724_M	0.758	0.49
19_V	22_G	0.756	0.48
150_A	153_S	0.755	0.48
299_N	314_F	0.753	0.48
352_S	488_I	0.753	0.48
231_G	241_N	0.752	0.48
599_L	609_L	0.752	0.48
422_K	470_Q	0.751	0.48
686_L	755_Q	0.751	0.48
458_E	461_Q	0.751	0.48
304_L	309_N	0.750	0.48
350_D	354_L	0.748	0.48
312_I	471_A	0.745	0.47
246_S	249_A	0.745	0.47
396_S	464_L	0.745	0.47
203_T	287_Q	0.743	0.47
472_D	476_S	0.743	0.47
26_S	34_Y	0.743	0.47
55_S	64_N	0.742	0.47
474_S	720_Q	0.741	0.47
10_M	45_G	0.741	0.47
60_M	63_Q	0.738	0.47
224_R	232_E	0.737	0.47
255_Q	777_L	0.733	0.46
258_I	272_M	0.733	0.46
725_D	754_G	0.733	0.46
209_M	781_L	0.732	0.46
610_M	616_H	0.731	0.46
632_C	637_L	0.731	0.46
539_L	561_L	0.730	0.46
41_L	44_A	0.729	0.46
299_N	712_F	0.729	0.46
333_T	399_P	0.728	0.46
272_M	723_D	0.728	0.46
56_T	64_N	0.728	0.46
366_F	512_F	0.728	0.46
615_C	619_V	0.727	0.46
108_M	429_I	0.727	0.46
467_A	750_H	0.727	0.46
90_D	94_R	0.725	0.46
308_L	418_G	0.724	0.45
298_A	304_L	0.724	0.45
412_I	439_S	0.722	0.45
461_Q	464_L	0.722	0.45
669_T	711_P	0.722	0.45
608_F	613_L	0.721	0.45
286_A	725_D	0.721	0.45
673_V	723_D	0.721	0.45
568_T	571_A	0.721	0.45
501_S	514_F	0.720	0.45
233_L	243_M	0.720	0.45
304_L	340_N	0.720	0.45
290_A	294_S	0.720	0.45
541_Y	553_L	0.719	0.45
53_A	57_E	0.719	0.45
764_M	767_Y	0.718	0.45
477_R	720_Q	0.718	0.45
399_P	445_I	0.715	0.45
449_I	670_V	0.714	0.45
422_K	455_G	0.714	0.45
579_M	583_G	0.713	0.44
10_M	14_I	0.713	0.44
299_N	764_M	0.713	0.44
299_N	755_Q	0.713	0.44
423_F	468_F	0.712	0.44
251_H	254_M	0.712	0.44
345_I	759_L	0.712	0.44
672_A	680_L	0.712	0.44
298_A	502_F	0.712	0.44
729_A	774_E	0.711	0.44
41_L	59_G	0.710	0.44
337_S	359_L	0.710	0.44
71_L	90_D	0.709	0.44
539_L	580_M	0.709	0.44
276_N	717_M	0.709	0.44
748_T	764_M	0.709	0.44
395_K	434_E	0.709	0.44
366_F	741_Q	0.709	0.44
52_L	59_G	0.708	0.44
242_S	245_M	0.708	0.44
86_I	445_I	0.708	0.44
494_N	499_D	0.707	0.44
200_R	613_L	0.706	0.44
316_R	686_L	0.706	0.44
39_R	52_L	0.705	0.44
746_A	763_G	0.704	0.44
314_F	410_Q	0.704	0.44
206_I	232_E	0.704	0.44
621_A	624_L	0.704	0.44
310_G	333_T	0.704	0.44
223_S	226_E	0.701	0.43
372_L	429_I	0.701	0.43
55_S	59_G	0.700	0.43
268_T	271_Q	0.698	0.43
236_L	247_L	0.698	0.43
685_A	717_M	0.698	0.43
717_M	727_I	0.698	0.43
751_A	755_Q	0.698	0.43
679_N	764_M	0.697	0.43
704_V	751_A	0.697	0.43
239_G	724_M	0.697	0.43
419_N	455_G	0.696	0.43
628_G	632_C	0.696	0.43
310_G	492_L	0.696	0.43
602_A	606_T	0.696	0.43
267_E	271_Q	0.695	0.43
75_L	87_S	0.694	0.43
376_V	582_L	0.694	0.43
118_R	121_T	0.694	0.43
309_N	476_S	0.693	0.43
668_M	692_Q	0.691	0.43
211_N	214_D	0.691	0.43
297_L	321_T	0.691	0.43
337_S	751_A	0.690	0.42
311_V	334_I	0.690	0.42
303_E	486_L	0.688	0.42
510_S	751_A	0.688	0.42
628_G	638_T	0.688	0.42
674_D	759_L	0.686	0.42
310_G	759_L	0.686	0.42
371_T	518_L	0.683	0.42
312_I	681_K	0.682	0.42
637_L	642_L	0.682	0.42
358_K	467_A	0.682	0.42
414_T	717_M	0.680	0.42
226_E	229_M	0.680	0.42
206_I	229_M	0.680	0.42
330_H	685_A	0.678	0.41
300_M	454_I	0.678	0.41
288_E	291_R	0.678	0.41
39_R	46_A	0.677	0.41
669_T	712_F	0.677	0.41
83_V	158_G	0.677	0.41
378_L	768_L	0.676	0.41
724_M	732_L	0.675	0.41
85_A	89_Y	0.675	0.41
340_N	356_A	0.674	0.41
227_G	231_G	0.674	0.41
733_I	744_V	0.674	0.41
314_F	747_V	0.673	0.41
315_T	729_A	0.672	0.41
460_D	480_G	0.672	0.41
561_L	742_T	0.672	0.41
282_A	359_L	0.671	0.41
286_A	355_E	0.671	0.41
318_T	355_E	0.671	0.41
409_L	425_E	0.670	0.41
169_V	402_V	0.669	0.41
636_P	645_A	0.669	0.41
193_I	782_L	0.668	0.40
465_F	500_I	0.668	0.40
288_E	292_I	0.668	0.40
120_L	670_V	0.667	0.40
419_N	483_G	0.667	0.40
384_H	464_L	0.667	0.40
538_R	564_V	0.667	0.40
48_I	60_M	0.666	0.40
611_L	616_H	0.666	0.40
361_L	495_E	0.666	0.40
338_A	421_I	0.665	0.40
699_S	702_Q	0.665	0.40
582_L	587_T	0.665	0.40
392_L	456_I	0.665	0.40
365_P	401_N	0.664	0.40
160_I	241_N	0.664	0.40
85_A	97_V	0.662	0.40
356_A	752_M	0.662	0.40
155_N	429_I	0.660	0.40
72_I	479_H	0.659	0.40
471_A	506_P	0.658	0.40
303_E	456_I	0.658	0.40
574_P	582_L	0.658	0.40
296_F	300_M	0.655	0.39
314_F	730_C	0.655	0.39
73_S	76_H	0.654	0.39
338_A	754_G	0.654	0.39
226_E	231_G	0.653	0.39
205_P	404_G	0.653	0.39
294_S	345_I	0.651	0.39
369_R	639_P	0.651	0.39
244_A	251_H	0.651	0.39
376_V	510_S	0.649	0.39
635_K	646_L	0.649	0.39
213_V	221_L	0.648	0.39
308_L	329_D	0.648	0.39
278_E	281_L	0.647	0.39
195_G	356_A	0.647	0.39
747_V	759_L	0.646	0.39
210_V	214_D	0.646	0.39
624_L	657_L	0.645	0.38
623_K	629_I	0.645	0.38
362_E	475_I	0.645	0.38
22_G	764_M	0.645	0.38
562_E	581_L	0.644	0.38
720_Q	729_A	0.644	0.38
394_I	402_V	0.644	0.38
541_Y	563_V	0.643	0.38
402_V	518_L	0.642	0.38
118_R	123_T	0.642	0.38
293_K	296_F	0.641	0.38
289_A	355_E	0.641	0.38
340_N	344_I	0.640	0.38
745_I	780_L	0.640	0.38
423_F	452_T	0.639	0.38
270_E	277_V	0.639	0.38
660_V	670_V	0.638	0.38
311_V	377_T	0.637	0.38
625_K	628_G	0.636	0.38
456_I	459_R	0.636	0.38
298_A	342_L	0.636	0.38
24_L	49_I	0.635	0.38
50_E	53_A	0.635	0.38
9_R	201_D	0.634	0.38
503_H	513_W	0.634	0.38
213_V	239_G	0.634	0.38
251_H	258_I	0.632	0.37
445_I	724_M	0.632	0.37
431_I	447_V	0.631	0.37
366_F	518_L	0.630	0.37
638_T	641_R	0.630	0.37
76_H	100_N	0.630	0.37
673_V	766_D	0.628	0.37
298_A	472_D	0.628	0.37
314_F	717_M	0.627	0.37
338_A	685_A	0.625	0.37
310_G	394_I	0.624	0.37
297_L	342_L	0.624	0.37
423_F	483_G	0.623	0.37
388_L	456_I	0.623	0.37
344_I	473_A	0.622	0.36
720_Q	751_A	0.622	0.36
319_L	733_I	0.622	0.36
40_Q	44_A	0.622	0.36
479_H	482_T	0.621	0.36
334_I	673_V	0.619	0.36
344_I	471_A	0.619	0.36
22_G	25_L	0.619	0.36
297_L	350_D	0.619	0.36
737_P	773_E	0.618	0.36
237_K	243_M	0.618	0.36
468_F	477_R	0.618	0.36
310_G	512_F	0.617	0.36
56_T	61_S	0.617	0.36
677_P	680_L	0.616	0.36
330_H	333_T	0.615	0.36
59_G	65_R	0.615	0.36
330_H	443_V	0.615	0.36
371_T	685_A	0.615	0.36
232_E	240_I	0.614	0.36
456_I	507_N	0.614	0.36
83_V	99_S	0.613	0.36
310_G	338_A	0.612	0.36
672_A	752_M	0.612	0.36
95_L	99_S	0.612	0.36
727_I	764_M	0.612	0.36
331_L	344_I	0.611	0.36
700_G	721_M	0.611	0.36
310_G	321_T	0.611	0.36
340_N	351_F	0.611	0.36
10_M	21_I	0.611	0.36
310_G	690_M	0.611	0.36
232_E	243_M	0.610	0.35
362_E	471_A	0.609	0.35
247_L	751_A	0.608	0.35
228_F	231_G	0.608	0.35
102_H	105_P	0.607	0.35
290_A	318_T	0.607	0.35
28_F	294_S	0.606	0.35
421_I	756_K	0.606	0.35
226_E	230_L	0.606	0.35
33_R	202_V	0.606	0.35
448_Q	514_F	0.604	0.35
635_K	640_T	0.604	0.35
24_L	203_T	0.604	0.35
340_N	748_T	0.603	0.35
472_D	478_R	0.603	0.35
244_A	248_A	0.603	0.35
487_V	510_S	0.602	0.35
700_G	724_M	0.602	0.35
697_C	703_A	0.602	0.35
475_I	727_I	0.602	0.35
704_V	728_R	0.601	0.35
240_I	246_S	0.601	0.35
680_L	692_Q	0.600	0.35
8_A	11_M	0.600	0.35
305_R	483_G	0.600	0.35
44_A	60_M	0.600	0.35
19_V	23_L	0.600	0.35
488_I	763_G	0.600	0.35
635_K	641_R	0.599	0.35
470_Q	482_T	0.599	0.35
361_L	371_T	0.599	0.35
303_E	306_T	0.599	0.35
332_N	582_L	0.599	0.35
626_Q	629_I	0.597	0.34
219_G	421_I	0.597	0.34
635_K	639_P	0.597	0.34
516_I	704_V	0.597	0.34
95_L	98_T	0.596	0.34
9_R	12_I	0.595	0.34
746_A	769_A	0.594	0.34
746_A	756_K	0.594	0.34
251_H	255_Q	0.592	0.34
464_L	755_Q	0.591	0.34
43_D	46_A	0.591	0.34
676_N	749_A	0.591	0.34
83_V	98_T	0.591	0.34
299_N	676_N	0.590	0.34
213_V	216_I	0.590	0.34
412_I	638_T	0.589	0.34
331_L	467_A	0.589	0.34
197_R	334_I	0.588	0.34
697_C	760_L	0.588	0.34
366_F	407_L	0.588	0.34
606_T	612_A	0.588	0.34
317_L	674_D	0.587	0.34
299_N	309_N	0.586	0.33
336_R	410_Q	0.585	0.33
232_E	241_N	0.584	0.33
717_M	748_T	0.584	0.33
353_K	479_H	0.583	0.33
18_T	28_F	0.583	0.33
364_I	480_G	0.583	0.33
336_R	759_L	0.581	0.33
254_M	331_L	0.580	0.33
312_I	330_H	0.579	0.33
299_N	472_D	0.579	0.33
227_G	238_N	0.579	0.33
636_P	640_T	0.578	0.33
383_S	580_M	0.578	0.33
297_L	477_R	0.576	0.33
339_N	751_A	0.576	0.33
293_K	355_E	0.576	0.33
501_S	510_S	0.575	0.33
382_S	747_V	0.575	0.33
640_T	644_P	0.575	0.33
299_N	747_V	0.575	0.33
414_T	421_I	0.574	0.33
358_K	490_Q	0.574	0.33
310_G	359_L	0.573	0.32
76_H	86_I	0.573	0.32
299_N	315_T	0.573	0.32
209_M	240_I	0.572	0.32
320_K	685_A	0.571	0.32
356_A	417_V	0.571	0.32
225_V	233_L	0.570	0.32
22_G	32_H	0.570	0.32
328_R	449_I	0.569	0.32
181_S	187_C	0.569	0.32
333_T	394_I	0.568	0.32
479_H	730_C	0.567	0.32
206_I	215_R	0.567	0.32
319_L	332_N	0.566	0.32
682_L	695_E	0.566	0.32
668_M	714_L	0.565	0.32
312_I	421_I	0.564	0.32
72_I	76_H	0.564	0.32
192_L	417_V	0.564	0.32
740_Q	765_S	0.564	0.32
455_G	483_G	0.563	0.32
399_P	752_M	0.563	0.32
676_N	679_N	0.563	0.32
103_L	107_S	0.562	0.32
425_E	478_R	0.560	0.31
474_S	478_R	0.560	0.31
10_M	18_T	0.560	0.31
493_V	498_G	0.559	0.31
388_L	746_A	0.559	0.31
410_Q	764_M	0.559	0.31
309_N	469_R	0.559	0.31
754_G	760_L	0.559	0.31
157_L	464_L	0.558	0.31
310_G	461_Q	0.558	0.31
340_N	674_D	0.558	0.31
672_A	720_Q	0.557	0.31
610_M	615_C	0.557	0.31
379_L	410_Q	0.556	0.31
37_L	412_I	0.555	0.31
372_L	447_V	0.555	0.31
331_L	673_V	0.554	0.31
721_M	763_G	0.553	0.31
534_L	539_L	0.553	0.31
230_L	234_D	0.553	0.31
314_F	685_A	0.553	0.31
45_G	48_I	0.552	0.31
314_F	373_D	0.552	0.31
417_V	754_G	0.551	0.31
730_C	748_T	0.551	0.31
316_R	729_A	0.550	0.31
344_I	367_P	0.550	0.31
290_A	362_E	0.549	0.31
631_A	635_K	0.549	0.31
129_M	133_T	0.549	0.31
686_L	753_A	0.547	0.30
187_C	337_S	0.547	0.30
258_I	268_T	0.547	0.30
686_L	773_E	0.547	0.30
680_L	744_V	0.545	0.30
317_L	773_E	0.545	0.30
326_T	674_D	0.545	0.30
357_G	399_P	0.545	0.30
298_A	470_Q	0.545	0.30
167_K	173_Q	0.544	0.30
87_S	98_T	0.544	0.30
254_M	262_T	0.544	0.30
36_D	41_L	0.544	0.30
338_A	392_L	0.544	0.30
407_L	686_L	0.544	0.30
544_P	564_V	0.544	0.30
292_I	304_L	0.543	0.30
314_F	725_D	0.543	0.30
452_T	773_E	0.543	0.30
609_L	614_P	0.543	0.30
380_A	383_S	0.543	0.30
314_F	333_T	0.543	0.30
314_F	340_N	0.542	0.30
303_E	327_Q	0.542	0.30
32_H	35_N	0.542	0.30
98_T	101_F	0.541	0.30
92_N	103_L	0.541	0.30
298_A	484_L	0.541	0.30
353_K	359_L	0.540	0.30
326_T	778_H	0.540	0.30
116_F	119_Q	0.540	0.30
351_F	488_I	0.539	0.30
309_N	479_H	0.539	0.30
680_L	750_H	0.539	0.30
238_N	241_N	0.538	0.30
331_L	461_Q	0.538	0.30
56_T	62_L	0.538	0.30
465_F	481_G	0.538	0.30
391_T	545_N	0.537	0.30
746_A	754_G	0.536	0.30
85_A	92_N	0.536	0.30
402_V	533_C	0.536	0.30
371_T	768_L	0.536	0.30
352_S	356_A	0.536	0.30
561_L	707_A	0.536	0.30
418_G	773_E	0.536	0.30
236_L	478_R	0.535	0.29
350_D	355_E	0.535	0.29
87_S	96_F	0.535	0.29
229_M	232_E	0.535	0.29
359_L	767_Y	0.535	0.29
26_S	30_V	0.534	0.29
29_F	52_L	0.534	0.29
55_S	60_M	0.534	0.29
250_Y	290_A	0.534	0.29
454_I	480_G	0.533	0.29
685_A	774_E	0.533	0.29
297_L	691_V	0.532	0.29
516_I	743_P	0.532	0.29
315_T	378_L	0.532	0.29
118_R	122_V	0.531	0.29
727_I	750_H	0.531	0.29
220_Q	231_G	0.531	0.29
314_F	686_L	0.531	0.29
365_P	394_I	0.530	0.29
581_L	628_G	0.530	0.29
504_S	510_S	0.529	0.29
684_G	694_V	0.529	0.29
616_H	619_V	0.529	0.29
13_L	17_P	0.529	0.29
309_N	717_M	0.529	0.29
13_L	163_E	0.529	0.29
53_A	58_Y	0.528	0.29
314_F	477_R	0.528	0.29
72_I	75_L	0.528	0.29
387_G	762_A	0.528	0.29
680_L	699_S	0.527	0.29
605_M	608_F	0.527	0.29
444_Q	515_H	0.526	0.29
751_A	758_K	0.526	0.29
202_V	209_M	0.526	0.29
337_S	752_M	0.526	0.29
55_S	62_L	0.526	0.29
721_M	726_G	0.526	0.29
674_D	692_Q	0.524	0.29
345_I	381_H	0.523	0.29
296_F	482_T	0.523	0.29
76_H	99_S	0.523	0.29
301_S	341_L	0.522	0.28
289_A	294_S	0.521	0.28
84_R	95_L	0.521	0.28
422_K	504_S	0.521	0.28
347_D	492_L	0.520	0.28
756_K	767_Y	0.520	0.28
516_I	575_A	0.520	0.28
304_L	373_D	0.519	0.28
422_K	483_G	0.519	0.28
52_L	60_M	0.519	0.28
733_I	737_P	0.518	0.28
704_V	733_I	0.518	0.28
604_S	611_L	0.518	0.28
320_K	361_L	0.518	0.28
382_S	729_A	0.517	0.28
323_L	331_L	0.517	0.28
354_L	752_M	0.517	0.28
725_D	730_C	0.517	0.28
179_I	355_E	0.517	0.28
314_F	727_I	0.515	0.28
293_K	301_S	0.515	0.28
327_Q	330_H	0.515	0.28
57_E	60_M	0.514	0.28
297_L	354_L	0.514	0.28
234_D	246_S	0.514	0.28
628_G	637_L	0.513	0.28
310_G	318_T	0.513	0.28
467_A	717_M	0.513	0.28
77_R	96_F	0.512	0.28
25_L	29_F	0.512	0.28
216_I	715_I	0.511	0.28
429_I	706_R	0.510	0.28
469_R	746_A	0.510	0.28
309_N	314_F	0.510	0.28
319_L	331_L	0.510	0.28
184_M	187_C	0.509	0.28
188_I	552_T	0.509	0.28
223_S	230_L	0.508	0.27
608_F	617_A	0.508	0.27
334_I	744_V	0.508	0.27
672_A	678_A	0.508	0.27
315_T	690_M	0.508	0.27
406_P	471_A	0.507	0.27
298_A	351_F	0.507	0.27
359_L	766_D	0.507	0.27
672_A	781_L	0.506	0.27
351_F	490_Q	0.506	0.27
717_M	733_I	0.506	0.27
233_L	236_L	0.506	0.27
10_M	24_L	0.505	0.27
543_E	549_A	0.505	0.27
337_S	676_N	0.504	0.27
456_I	463_R	0.504	0.27
460_D	676_N	0.503	0.27
29_F	33_R	0.503	0.27
345_I	390_L	0.503	0.27
730_C	734_H	0.503	0.27
332_N	673_V	0.502	0.27
276_N	314_F	0.502	0.27
410_Q	748_T	0.502	0.27
300_M	751_A	0.502	0.27
568_T	572_L	0.502	0.27
423_F	465_F	0.502	0.27
686_L	747_V	0.501	0.27
346_N	350_D	0.501	0.27
416_L	449_I	0.500	0.27
145_S	150_A	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.3377	100	0.75	Contact Map
4bixA	2	0.2495	100	0.78	Contact Map
4e01A	3	0.3083	100	0.787	Contact Map
4mpcA	2	0.3606	100	0.789	Contact Map
4ctiA	2	0.2484	100	0.792	Contact Map
4gczA	2	0.3802	100	0.793	Contact Map
2q8gA	2	0.3475	100	0.796	Contact Map
2c2aA	2	0.2538	100	0.797	Contact Map
4q20A	2	0.2505	100	0.8	Contact Map
3jz3A	2	0.1743	100	0.802	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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