ARCB - ECOLI - GREMLIN Contacts

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ARCB - Aerobic respiration control sensor protein ArcB

UniProt:	P0AEC3	Sequences: MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEKVFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQVITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSVAEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDDVLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10062
Length:	778 (622)
Sequences:	1802 (1558)
Seq/√Len:	62.5

ECOLI - ARCB EVGS BARA TORS RCSD RCSC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
553_D	570_Y	7.155	1.00
269_R	273_Q	5.048	1.00
557_T	581_D	4.218	1.00
356_V	394_T	4.196	1.00
556_M	560_A	4.058	1.00
538_V	554_V	4.008	1.00
166_D	264_R	3.932	1.00
447_L	489_V	3.906	1.00
273_Q	276_L	3.890	1.00
407_I	421_V	3.864	1.00
443_P	446_E	3.666	1.00
575_L	587_I	3.583	1.00
488_T	500_T	3.561	1.00
305_S	324_I	3.473	1.00
708_D	711_G	3.347	1.00
477_R	481_K	3.312	1.00
270_K	273_Q	3.238	1.00
532_E	538_V	3.220	1.00
313_L	317_Q	3.205	1.00
615_Q	619_N	3.170	1.00
272_Y	276_L	3.163	1.00
559_K	581_D	3.146	1.00
530_L	541_A	3.131	1.00
311_T	317_Q	3.092	1.00
492_E	495_K	3.045	1.00
575_L	588_S	2.954	1.00
480_A	501_L	2.949	1.00
402_I	480_A	2.877	1.00
583_T	586_D	2.818	1.00
555_A	564_M	2.771	1.00
269_R	272_Y	2.756	1.00
586_D	590_E	2.736	1.00
442_I	446_E	2.723	1.00
562_L	587_I	2.713	1.00
600_L	623_D	2.620	1.00
433_F	501_L	2.614	1.00
172_N	176_E	2.607	1.00
354_Q	396_G	2.604	1.00
573_V	601_P	2.541	1.00
169_F	261_G	2.518	1.00
566_K	594_R	2.460	1.00
355_P	393_I	2.427	1.00
269_R	276_L	2.424	1.00
538_V	556_M	2.416	1.00
588_S	603_L	2.376	1.00
154_S	158_R	2.373	1.00
414_T	438_S	2.372	1.00
403_L	433_F	2.370	1.00
588_S	622_M	2.363	1.00
394_T	483_M	2.332	1.00
565_F	573_V	2.325	1.00
234_Y	238_R	2.320	1.00
531_V	555_A	2.318	1.00
190_K	235_P	2.317	1.00
432_H	502_T	2.309	1.00
527_N	551_S	2.295	1.00
302_V	328_A	2.251	1.00
357_D	390_H	2.247	1.00
372_Q	375_Q	2.245	1.00
559_K	563_E	2.123	1.00
481_K	486_D	2.089	1.00
562_L	565_F	2.083	1.00
462_G	467_T	2.065	1.00
531_V	561_A	2.050	1.00
443_P	493_Q	2.047	1.00
229_E	270_K	2.039	1.00
290_I	294_L	2.038	1.00
624_D	642_F	2.006	1.00
310_D	547_K	1.992	1.00
432_H	500_T	1.980	1.00
304_L	540_V	1.968	1.00
355_P	508_V	1.956	1.00
167_L	263_G	1.930	1.00
298_L	335_F	1.930	1.00
716_G	742_D	1.929	1.00
577_I	585_L	1.925	1.00
617_Y	622_M	1.871	1.00
592_T	623_D	1.868	1.00
590_E	593_K	1.828	1.00
462_G	466_A	1.826	1.00
624_D	641_K	1.825	1.00
277_E	280_S	1.820	1.00
167_L	187_L	1.816	1.00
458_K	464_K	1.813	1.00
314_T	317_Q	1.812	1.00
422_R	436_E	1.808	1.00
526_L	643_W	1.803	1.00
457_V	462_G	1.788	1.00
572_L	639_I	1.775	1.00
365_L	407_I	1.760	0.99
343_K	469_T	1.732	0.99
373_A	411_V	1.731	0.99
701_E	758_K	1.701	0.99
392_V	505_A	1.696	0.99
422_R	434_E	1.690	0.99
434_E	498_T	1.676	0.99
724_G	732_Q	1.669	0.99
319_K	539_I	1.664	0.99
143_R	147_Q	1.663	0.99
243_E	264_R	1.650	0.99
311_T	320_Y	1.648	0.99
280_S	284_T	1.647	0.99
389_P	392_V	1.636	0.99
383_E	422_R	1.628	0.99
169_F	177_F	1.623	0.99
525_A	550_N	1.621	0.99
446_E	449_K	1.605	0.99
585_L	617_Y	1.604	0.99
573_V	603_L	1.601	0.99
614_K	618_L	1.592	0.99
605_A	622_M	1.589	0.99
548_L	636_T	1.583	0.99
418_Q	438_S	1.581	0.99
309_L	318_E	1.570	0.99
402_I	479_L	1.566	0.99
624_D	638_M	1.563	0.99
316_E	543_S	1.561	0.99
191_S	194_Q	1.550	0.99
430_M	504_H	1.546	0.99
418_Q	436_E	1.545	0.99
300_G	536_L	1.540	0.99
480_A	485_G	1.539	0.99
384_P	388_L	1.538	0.99
369_S	411_V	1.535	0.99
577_I	609_N	1.533	0.99
577_I	617_Y	1.531	0.99
442_I	447_L	1.527	0.99
373_A	419_V	1.525	0.99
542_R	546_E	1.511	0.98
266_I	270_K	1.509	0.98
595_Y	600_L	1.504	0.98
170_Y	181_N	1.497	0.98
430_M	502_T	1.497	0.98
369_S	404_W	1.496	0.98
300_G	327_S	1.494	0.98
528_V	550_N	1.480	0.98
353_N	506_P	1.478	0.98
565_F	601_P	1.477	0.98
526_L	550_N	1.472	0.98
703_N	708_D	1.472	0.98
194_Q	235_P	1.471	0.98
501_L	504_H	1.470	0.98
523_L	550_N	1.469	0.98
158_R	162_D	1.466	0.98
717_H	721_G	1.459	0.98
279_A	282_D	1.457	0.98
457_V	467_T	1.451	0.98
613_D	616_E	1.447	0.98
251_D	255_K	1.441	0.98
147_Q	151_E	1.436	0.98
532_E	554_V	1.432	0.98
402_I	501_L	1.428	0.98
294_L	298_L	1.425	0.98
553_D	568_G	1.421	0.98
553_D	564_M	1.419	0.98
582_M	586_D	1.417	0.98
290_I	338_I	1.416	0.98
460_S	463_G	1.412	0.98
604_V	638_M	1.407	0.97
353_N	394_T	1.397	0.97
205_S	208_A	1.395	0.97
423_V	433_F	1.382	0.97
585_L	616_E	1.382	0.97
306_R	325_H	1.379	0.97
582_M	590_E	1.378	0.97
164_S	168_V	1.367	0.97
444_Q	492_E	1.363	0.97
366_E	380_F	1.360	0.97
557_T	560_A	1.353	0.97
306_R	632_V	1.351	0.97
610_V	627_S	1.344	0.97
309_L	322_K	1.340	0.97
565_F	594_R	1.338	0.97
530_L	552_V	1.334	0.97
591_L	603_L	1.334	0.97
208_A	231_W	1.332	0.96
689_F	723_A	1.331	0.96
578_Q	609_N	1.325	0.96
308_L	321_L	1.324	0.96
362_L	423_V	1.321	0.96
436_E	498_T	1.300	0.96
170_Y	258_G	1.299	0.96
712_I	742_D	1.298	0.96
480_A	487_I	1.287	0.96
177_F	216_D	1.277	0.96
527_N	553_D	1.274	0.95
184_M	188_T	1.263	0.95
760_E	763_H	1.263	0.95
542_R	554_V	1.262	0.95
464_K	467_T	1.248	0.95
526_L	642_F	1.245	0.95
489_V	499_F	1.243	0.95
398_R	401_Q	1.243	0.95
457_V	466_A	1.241	0.95
308_L	317_Q	1.239	0.95
562_L	575_L	1.236	0.95
276_L	282_D	1.234	0.95
394_T	505_A	1.232	0.95
575_L	591_L	1.231	0.95
456_Q	467_T	1.231	0.95
284_T	345_E	1.231	0.95
349_V	398_R	1.225	0.94
190_K	194_Q	1.224	0.94
181_N	184_M	1.221	0.94
398_R	483_M	1.218	0.94
379_R	418_Q	1.211	0.94
490_T	498_T	1.209	0.94
380_F	421_V	1.208	0.94
298_L	328_A	1.203	0.94
574_L	635_L	1.201	0.94
287_I	290_I	1.195	0.94
364_D	400_R	1.192	0.94
171_R	177_F	1.188	0.93
156_F	170_Y	1.186	0.93
564_M	570_Y	1.186	0.93
289_T	578_Q	1.179	0.93
535_E	538_V	1.170	0.93
327_S	536_L	1.169	0.93
612_K	615_Q	1.165	0.93
406_L	487_I	1.161	0.93
434_E	500_T	1.158	0.92
161_L	179_G	1.158	0.92
587_I	591_L	1.157	0.92
424_R	434_E	1.155	0.92
735_G	757_M	1.138	0.92
329_V	631_S	1.137	0.92
577_I	622_M	1.137	0.92
413_F	456_Q	1.136	0.92
443_P	447_L	1.135	0.92
528_V	572_L	1.134	0.92
477_R	487_I	1.131	0.92
534_I	722_A	1.131	0.92
171_R	246_K	1.125	0.91
151_E	154_S	1.125	0.91
240_A	267_T	1.124	0.91
399_L	505_A	1.117	0.91
420_T	438_S	1.116	0.91
555_A	558_G	1.114	0.91
180_C	184_M	1.113	0.91
717_H	739_Q	1.112	0.91
606_L	617_Y	1.108	0.91
738_I	757_M	1.104	0.91
720_K	736_Q	1.101	0.90
231_W	241_C	1.096	0.90
311_T	314_T	1.093	0.90
244_I	263_G	1.093	0.90
385_T	388_L	1.092	0.90
146_T	149_Q	1.091	0.90
527_N	571_D	1.089	0.90
541_A	606_L	1.088	0.90
460_S	466_A	1.088	0.90
666_D	672_Q	1.083	0.90
230_Q	244_I	1.079	0.90
478_R	482_N	1.076	0.89
676_L	679_P	1.073	0.89
746_W	749_N	1.072	0.89
161_L	181_N	1.072	0.89
458_K	463_G	1.070	0.89
531_V	573_V	1.068	0.89
452_A	455_Y	1.067	0.89
166_D	183_A	1.067	0.89
406_L	501_L	1.066	0.89
352_D	462_G	1.064	0.89
357_D	360_S	1.063	0.89
476_S	487_I	1.061	0.89
352_D	394_T	1.059	0.89
171_R	216_D	1.059	0.89
342_D	346_R	1.056	0.89
170_Y	261_G	1.056	0.89
205_S	231_W	1.053	0.88
575_L	603_L	1.053	0.88
279_A	284_T	1.050	0.88
154_S	157_L	1.039	0.88
164_S	167_L	1.038	0.88
332_G	336_N	1.035	0.88
723_A	731_L	1.028	0.87
602_P	623_D	1.026	0.87
246_K	261_G	1.026	0.87
420_T	436_E	1.021	0.87
460_S	464_K	1.021	0.87
216_D	246_K	1.015	0.86
442_I	489_V	1.015	0.86
550_N	642_F	1.014	0.86
358_F	392_V	1.012	0.86
167_L	181_N	1.011	0.86
607_T	625_V	1.009	0.86
219_V	248_P	1.007	0.86
268_E	271_R	1.001	0.86
614_K	624_D	1.001	0.86
443_P	450_I	0.998	0.86
277_E	282_D	0.986	0.85
672_Q	676_L	0.984	0.85
343_K	456_Q	0.984	0.85
531_V	557_T	0.983	0.85
333_N	397_T	0.976	0.84
696_Y	718_K	0.976	0.84
316_E	547_K	0.974	0.84
300_G	305_S	0.974	0.84
166_D	181_N	0.972	0.84
760_E	764_D	0.971	0.84
170_Y	260_M	0.969	0.84
351_L	483_M	0.966	0.84
171_R	258_G	0.964	0.84
234_Y	240_A	0.963	0.83
219_V	223_N	0.962	0.83
171_R	200_P	0.961	0.83
305_S	325_H	0.961	0.83
381_N	418_Q	0.960	0.83
544_V	632_V	0.960	0.83
313_L	321_L	0.952	0.83
318_E	322_K	0.951	0.83
248_P	258_G	0.950	0.83
172_N	258_G	0.950	0.83
383_E	420_T	0.948	0.82
609_N	617_Y	0.947	0.82
320_Y	543_S	0.947	0.82
153_Q	156_F	0.946	0.82
548_L	632_V	0.943	0.82
579_L	587_I	0.943	0.82
668_P	672_Q	0.942	0.82
144_E	147_Q	0.941	0.82
271_R	275_A	0.939	0.82
565_F	595_Y	0.937	0.82
298_L	369_S	0.937	0.82
335_F	610_V	0.936	0.82
558_G	582_M	0.935	0.82
305_S	328_A	0.935	0.82
573_V	587_I	0.934	0.82
173_E	256_R	0.932	0.81
157_L	160_F	0.929	0.81
563_E	567_P	0.925	0.81
402_I	476_S	0.924	0.81
171_R	180_C	0.923	0.81
169_F	184_M	0.923	0.81
337_D	398_R	0.923	0.81
277_E	281_R	0.922	0.81
751_G	755_E	0.919	0.80
626_L	638_M	0.917	0.80
589_R	620_A	0.916	0.80
323_T	327_S	0.916	0.80
692_M	695_G	0.914	0.80
181_N	265_D	0.911	0.80
302_V	332_G	0.908	0.80
456_Q	466_A	0.907	0.80
306_R	631_S	0.907	0.80
161_L	168_V	0.906	0.80
310_D	632_V	0.905	0.79
526_L	571_D	0.902	0.79
716_G	735_G	0.901	0.79
302_V	305_S	0.899	0.79
232_L	240_A	0.898	0.79
531_V	582_M	0.892	0.78
714_E	718_K	0.881	0.78
370_A	374_Q	0.880	0.77
182_R	186_L	0.879	0.77
413_F	467_T	0.877	0.77
540_V	543_S	0.877	0.77
565_F	591_L	0.877	0.77
721_G	724_G	0.877	0.77
352_D	464_K	0.876	0.77
326_V	364_D	0.871	0.77
170_Y	179_G	0.869	0.77
693_M	696_Y	0.868	0.77
143_R	146_T	0.865	0.76
737_Q	741_P	0.864	0.76
577_I	605_A	0.864	0.76
723_A	735_G	0.863	0.76
160_F	167_L	0.863	0.76
168_V	264_R	0.862	0.76
369_S	408_S	0.862	0.76
305_S	321_L	0.858	0.76
444_Q	493_Q	0.858	0.76
440_I	466_A	0.858	0.76
696_Y	715_E	0.857	0.76
227_T	243_E	0.856	0.76
207_E	231_W	0.855	0.75
424_R	432_H	0.855	0.75
581_D	587_I	0.855	0.75
434_E	501_L	0.853	0.75
330_T	334_I	0.850	0.75
609_N	613_D	0.850	0.75
229_E	269_R	0.848	0.75
666_D	670_L	0.848	0.75
414_T	417_G	0.848	0.75
162_D	182_R	0.847	0.75
180_C	185_E	0.847	0.75
177_F	180_C	0.846	0.75
165_P	170_Y	0.844	0.74
168_V	181_N	0.844	0.74
188_T	232_L	0.843	0.74
532_E	579_L	0.843	0.74
703_N	711_G	0.842	0.74
555_A	560_A	0.841	0.74
579_L	582_M	0.841	0.74
160_F	260_M	0.839	0.74
689_F	693_M	0.837	0.74
458_K	462_G	0.836	0.74
323_T	539_I	0.834	0.74
213_I	217_E	0.834	0.74
484_G	501_L	0.834	0.74
373_A	377_G	0.832	0.73
300_G	334_I	0.831	0.73
446_E	450_I	0.829	0.73
546_E	552_V	0.829	0.73
369_S	609_N	0.827	0.73
450_I	474_A	0.827	0.73
721_G	725_S	0.826	0.73
378_L	414_T	0.826	0.73
585_L	726_V	0.824	0.73
167_L	184_M	0.823	0.73
562_L	591_L	0.823	0.73
572_L	606_L	0.822	0.73
722_A	725_S	0.821	0.72
579_L	607_T	0.821	0.72
323_T	536_L	0.819	0.72
536_L	540_V	0.818	0.72
287_I	344_M	0.818	0.72
682_I	686_L	0.817	0.72
175_K	181_N	0.814	0.72
309_L	325_H	0.809	0.71
446_E	457_V	0.808	0.71
626_L	630_L	0.808	0.71
150_L	153_Q	0.807	0.71
351_L	398_R	0.807	0.71
183_A	186_L	0.806	0.71
391_Q	508_V	0.806	0.71
243_E	269_R	0.806	0.71
669_M	672_Q	0.806	0.71
755_E	758_K	0.805	0.71
231_W	239_K	0.801	0.71
278_R	282_D	0.801	0.71
280_S	283_K	0.798	0.70
300_G	304_L	0.797	0.70
531_V	541_A	0.796	0.70
305_S	309_L	0.795	0.70
672_Q	677_V	0.790	0.70
703_N	715_E	0.790	0.70
276_L	280_S	0.789	0.69
289_T	613_D	0.786	0.69
284_T	630_L	0.783	0.69
184_M	241_C	0.783	0.69
579_L	583_T	0.783	0.69
165_P	169_F	0.783	0.69
734_L	737_Q	0.782	0.69
707_Q	712_I	0.779	0.68
402_I	483_M	0.776	0.68
446_E	466_A	0.772	0.68
294_L	609_N	0.770	0.68
753_W	756_E	0.770	0.68
356_V	399_L	0.767	0.67
233_D	239_K	0.766	0.67
340_D	398_R	0.766	0.67
489_V	497_S	0.765	0.67
413_F	466_A	0.765	0.67
476_S	501_L	0.765	0.67
592_T	595_Y	0.765	0.67
165_P	248_P	0.764	0.67
246_K	259_L	0.763	0.67
399_L	433_F	0.761	0.67
160_F	170_Y	0.761	0.67
351_L	399_L	0.759	0.66
544_V	575_L	0.759	0.66
574_L	605_A	0.759	0.66
200_P	230_Q	0.757	0.66
575_L	605_A	0.757	0.66
166_D	260_M	0.756	0.66
376_K	415_Q	0.755	0.66
177_F	202_D	0.755	0.66
300_G	308_L	0.755	0.66
352_D	396_G	0.755	0.66
185_E	259_L	0.752	0.66
248_P	256_R	0.752	0.66
352_D	466_A	0.751	0.66
380_F	411_V	0.751	0.66
206_P	231_W	0.750	0.65
678_G	681_L	0.750	0.65
369_S	407_I	0.750	0.65
557_T	587_I	0.750	0.65
562_L	603_L	0.750	0.65
407_I	411_V	0.749	0.65
578_Q	613_D	0.748	0.65
388_L	431_L	0.746	0.65
483_M	505_A	0.745	0.65
610_V	625_V	0.744	0.65
343_K	346_R	0.743	0.65
562_L	590_E	0.742	0.65
366_E	421_V	0.741	0.65
356_V	505_A	0.740	0.64
189_G	235_P	0.740	0.64
713_V	743_L	0.739	0.64
673_Y	676_L	0.738	0.64
719_I	735_G	0.738	0.64
405_N	412_K	0.736	0.64
666_D	669_M	0.736	0.64
296_T	608_A	0.734	0.64
157_L	170_Y	0.734	0.64
758_K	762_R	0.733	0.64
720_K	739_Q	0.732	0.64
304_L	320_Y	0.732	0.64
442_I	448_D	0.732	0.64
536_L	539_I	0.731	0.63
531_V	562_L	0.730	0.63
531_V	581_D	0.730	0.63
169_F	180_C	0.730	0.63
155_S	158_R	0.730	0.63
450_I	489_V	0.727	0.63
666_D	674_L	0.727	0.63
563_E	566_K	0.727	0.63
453_M	474_A	0.725	0.63
393_I	508_V	0.725	0.63
614_K	625_V	0.725	0.63
325_H	329_V	0.724	0.63
157_L	161_L	0.724	0.63
533_D	608_A	0.723	0.63
217_E	221_R	0.722	0.63
300_G	540_V	0.722	0.63
163_A	170_Y	0.720	0.62
251_D	258_G	0.720	0.62
160_F	165_P	0.719	0.62
198_L	202_D	0.719	0.62
559_K	582_M	0.717	0.62
204_Y	209_A	0.715	0.62
639_I	642_F	0.715	0.62
211_K	214_E	0.712	0.61
268_E	273_Q	0.712	0.61
463_G	466_A	0.712	0.61
734_L	753_W	0.710	0.61
161_L	183_A	0.707	0.61
532_E	557_T	0.707	0.61
449_K	455_Y	0.707	0.61
539_I	684_D	0.706	0.61
167_L	242_F	0.706	0.61
456_Q	469_T	0.706	0.61
561_A	565_F	0.704	0.61
381_N	420_T	0.704	0.61
351_L	482_N	0.703	0.60
176_E	199_K	0.703	0.60
206_P	209_A	0.701	0.60
212_V	215_T	0.700	0.60
485_G	501_L	0.699	0.60
373_A	378_L	0.699	0.60
477_R	480_A	0.699	0.60
531_V	558_G	0.698	0.60
307_I	320_Y	0.697	0.60
574_L	604_V	0.695	0.60
352_D	460_S	0.695	0.60
181_N	260_M	0.695	0.60
710_K	714_E	0.693	0.59
692_M	696_Y	0.693	0.59
359_T	390_H	0.692	0.59
432_H	488_T	0.690	0.59
462_G	465_P	0.690	0.59
458_K	465_P	0.689	0.59
169_F	246_K	0.689	0.59
188_T	262_F	0.688	0.59
171_R	259_L	0.688	0.59
280_S	335_F	0.687	0.59
417_G	438_S	0.686	0.59
488_T	501_L	0.686	0.59
415_Q	466_A	0.684	0.58
529_L	555_A	0.684	0.58
281_R	285_T	0.684	0.58
490_T	500_T	0.683	0.58
734_L	738_I	0.682	0.58
671_E	676_L	0.682	0.58
527_N	570_Y	0.680	0.58
171_R	248_P	0.680	0.58
176_E	198_L	0.680	0.58
147_Q	150_L	0.679	0.58
166_D	263_G	0.678	0.58
166_D	184_M	0.678	0.58
605_A	627_S	0.677	0.58
246_K	263_G	0.676	0.57
458_K	466_A	0.675	0.57
610_V	617_Y	0.675	0.57
352_D	467_T	0.674	0.57
177_F	200_P	0.672	0.57
572_L	643_W	0.672	0.57
572_L	602_P	0.672	0.57
271_R	276_L	0.671	0.57
319_K	323_T	0.671	0.57
299_N	537_N	0.669	0.57
724_G	736_Q	0.668	0.57
606_L	626_L	0.667	0.56
149_Q	154_S	0.667	0.56
491_S	495_K	0.667	0.56
177_F	246_K	0.666	0.56
575_L	579_L	0.664	0.56
730_H	763_H	0.662	0.56
604_V	642_F	0.662	0.56
460_S	467_T	0.661	0.56
447_L	453_M	0.661	0.56
442_I	450_I	0.660	0.56
397_T	400_R	0.659	0.56
700_L	716_G	0.658	0.55
667_I	671_E	0.657	0.55
165_P	260_M	0.656	0.55
169_F	244_I	0.655	0.55
170_Y	177_F	0.655	0.55
249_Y	258_G	0.655	0.55
365_L	404_W	0.655	0.55
232_L	263_G	0.654	0.55
177_F	261_G	0.654	0.55
592_T	601_P	0.653	0.55
415_Q	465_P	0.653	0.55
400_R	404_W	0.652	0.55
607_T	617_Y	0.652	0.55
531_V	591_L	0.649	0.54
323_T	543_S	0.647	0.54
429_D	487_I	0.645	0.54
328_A	396_G	0.645	0.54
301_I	435_V	0.645	0.54
720_K	724_G	0.645	0.54
385_T	424_R	0.644	0.54
365_L	531_V	0.644	0.54
204_Y	208_A	0.643	0.54
578_Q	606_L	0.642	0.54
189_G	237_G	0.642	0.54
716_G	739_Q	0.641	0.54
246_K	260_M	0.640	0.53
607_T	610_V	0.640	0.53
229_E	266_I	0.639	0.53
402_I	590_E	0.639	0.53
306_R	375_Q	0.638	0.53
485_G	504_H	0.638	0.53
674_L	678_G	0.637	0.53
293_E	537_N	0.636	0.53
526_L	572_L	0.635	0.53
574_L	587_I	0.634	0.53
668_P	677_V	0.634	0.53
534_I	541_A	0.634	0.53
170_Y	184_M	0.634	0.53
555_A	573_V	0.633	0.53
730_H	733_Q	0.633	0.53
544_V	587_I	0.632	0.52
691_K	695_G	0.632	0.52
491_S	494_G	0.632	0.52
200_P	246_K	0.631	0.52
598_E	601_P	0.631	0.52
180_C	195_L	0.631	0.52
300_G	337_D	0.630	0.52
594_R	597_R	0.630	0.52
716_G	738_I	0.630	0.52
532_E	536_L	0.629	0.52
160_F	263_G	0.629	0.52
209_A	212_V	0.629	0.52
169_F	249_Y	0.628	0.52
617_Y	621_G	0.627	0.52
298_L	323_T	0.627	0.52
736_Q	740_S	0.626	0.52
486_D	502_T	0.626	0.52
456_Q	462_G	0.625	0.52
306_R	323_T	0.625	0.52
406_L	503_I	0.624	0.52
199_K	202_D	0.624	0.52
528_V	552_V	0.622	0.51
626_L	707_Q	0.622	0.51
168_V	171_R	0.622	0.51
741_P	746_W	0.621	0.51
613_D	622_M	0.621	0.51
380_F	407_I	0.621	0.51
363_A	367_N	0.621	0.51
704_L	712_I	0.620	0.51
552_V	555_A	0.620	0.51
699_V	711_G	0.618	0.51
247_V	260_M	0.617	0.51
589_R	593_K	0.616	0.51
177_F	184_M	0.615	0.51
592_T	603_L	0.615	0.51
563_E	581_D	0.615	0.51
160_F	262_F	0.614	0.50
476_S	481_K	0.613	0.50
712_I	716_G	0.612	0.50
670_L	674_L	0.611	0.50
555_A	561_A	0.611	0.50
280_S	338_I	0.611	0.50
575_L	622_M	0.610	0.50
356_V	575_L	0.609	0.50
464_K	578_Q	0.609	0.50
550_N	624_D	0.608	0.50
404_W	544_V	0.608	0.50
572_L	642_F	0.605	0.49
525_A	551_S	0.604	0.49
240_A	265_D	0.604	0.49
393_I	506_P	0.602	0.49
544_V	548_L	0.602	0.49
721_G	739_Q	0.602	0.49
595_Y	623_D	0.601	0.49
302_V	309_L	0.601	0.49
200_P	206_P	0.601	0.49
385_T	431_L	0.600	0.49
388_L	425_Y	0.599	0.49
309_L	312_E	0.598	0.49
694_P	765_V	0.598	0.49
368_L	450_I	0.597	0.48
730_H	734_L	0.596	0.48
259_L	263_G	0.595	0.48
219_V	246_K	0.595	0.48
718_K	735_G	0.594	0.48
232_L	261_G	0.593	0.48
200_P	263_G	0.592	0.48
324_I	328_A	0.591	0.48
731_L	757_M	0.591	0.48
450_I	501_L	0.591	0.48
171_R	263_G	0.590	0.48
450_I	483_M	0.589	0.48
634_A	637_A	0.589	0.48
560_A	564_M	0.589	0.48
205_S	233_D	0.588	0.47
147_Q	152_Q	0.588	0.47
617_Y	728_L	0.587	0.47
709_K	746_W	0.587	0.47
357_D	615_Q	0.587	0.47
301_I	319_K	0.587	0.47
302_V	306_R	0.586	0.47
287_I	302_V	0.586	0.47
355_P	391_Q	0.585	0.47
308_L	320_Y	0.584	0.47
171_R	184_M	0.584	0.47
497_S	500_T	0.583	0.47
683_T	687_A	0.583	0.47
298_L	338_I	0.583	0.47
665_L	670_L	0.583	0.47
304_L	307_I	0.582	0.47
178_S	232_L	0.582	0.47
169_F	259_L	0.581	0.47
368_L	404_W	0.581	0.47
492_E	734_L	0.580	0.47
587_I	605_A	0.580	0.47
212_V	219_V	0.580	0.47
455_Y	474_A	0.579	0.46
720_K	726_V	0.579	0.46
378_L	735_G	0.579	0.46
189_G	194_Q	0.578	0.46
433_F	500_T	0.576	0.46
241_C	246_K	0.576	0.46
341_M	450_I	0.576	0.46
731_L	735_G	0.576	0.46
242_F	263_G	0.575	0.46
240_A	246_K	0.574	0.46
671_E	674_L	0.573	0.46
241_C	264_R	0.573	0.46
148_I	151_E	0.573	0.46
299_N	606_L	0.572	0.46
325_H	431_L	0.570	0.45
181_N	261_G	0.569	0.45
166_D	243_E	0.569	0.45
301_I	324_I	0.568	0.45
304_L	334_I	0.568	0.45
550_N	643_W	0.568	0.45
603_L	622_M	0.568	0.45
346_R	454_Y	0.567	0.45
308_L	313_L	0.567	0.45
388_L	392_V	0.566	0.45
149_Q	153_Q	0.565	0.45
209_A	216_D	0.565	0.45
435_V	501_L	0.565	0.45
161_L	165_P	0.565	0.45
344_M	479_L	0.564	0.45
157_L	165_P	0.564	0.45
142_E	145_E	0.564	0.45
205_S	246_K	0.564	0.45
480_A	503_I	0.564	0.45
150_L	158_R	0.563	0.45
342_D	474_A	0.563	0.45
751_G	759_E	0.563	0.45
265_D	532_E	0.563	0.45
433_F	505_A	0.562	0.44
440_I	457_V	0.562	0.44
307_I	543_S	0.562	0.44
275_A	757_M	0.562	0.44
579_L	608_A	0.561	0.44
161_L	170_Y	0.561	0.44
205_S	241_C	0.561	0.44
542_R	570_Y	0.559	0.44
689_F	739_Q	0.558	0.44
362_L	403_L	0.558	0.44
273_Q	277_E	0.557	0.44
243_E	246_K	0.557	0.44
327_S	534_I	0.557	0.44
749_N	753_W	0.556	0.44
361_F	505_A	0.555	0.44
545_L	552_V	0.554	0.44
262_F	528_V	0.554	0.44
324_I	446_E	0.553	0.43
604_V	624_D	0.553	0.43
298_L	330_T	0.553	0.43
728_L	764_D	0.553	0.43
343_K	349_V	0.553	0.43
610_V	618_L	0.553	0.43
290_I	332_G	0.553	0.43
168_V	246_K	0.553	0.43
178_S	419_V	0.552	0.43
596_P	600_L	0.552	0.43
590_E	594_R	0.551	0.43
384_P	423_V	0.551	0.43
337_D	401_Q	0.551	0.43
679_P	683_T	0.551	0.43
700_L	712_I	0.550	0.43
366_E	382_L	0.550	0.43
293_E	456_Q	0.549	0.43
388_L	490_T	0.549	0.43
180_C	192_E	0.549	0.43
177_F	230_Q	0.549	0.43
162_D	181_N	0.548	0.43
200_P	248_P	0.548	0.43
540_V	627_S	0.548	0.43
533_D	579_L	0.547	0.43
149_Q	152_Q	0.547	0.43
164_S	243_E	0.546	0.43
294_L	338_I	0.544	0.42
404_W	408_S	0.543	0.42
435_V	481_K	0.542	0.42
176_E	202_D	0.542	0.42
696_Y	722_A	0.541	0.42
316_E	320_Y	0.541	0.42
219_V	222_H	0.541	0.42
200_P	205_S	0.540	0.42
306_R	400_R	0.540	0.42
553_D	571_D	0.539	0.42
562_L	594_R	0.539	0.42
165_P	264_R	0.539	0.42
442_I	445_D	0.539	0.42
288_S	458_K	0.538	0.42
218_K	222_H	0.537	0.42
324_I	605_A	0.537	0.42
280_S	617_Y	0.537	0.42
187_L	208_A	0.536	0.42
161_L	164_S	0.535	0.41
443_P	593_K	0.535	0.41
185_E	195_L	0.535	0.41
166_D	179_G	0.535	0.41
437_D	496_G	0.534	0.41
358_F	431_L	0.534	0.41
288_S	291_S	0.534	0.41
340_D	343_K	0.534	0.41
395_D	398_R	0.533	0.41
476_S	484_G	0.533	0.41
166_D	262_F	0.532	0.41
334_I	341_M	0.532	0.41
611_L	625_V	0.531	0.41
172_N	220_F	0.531	0.41
226_L	241_C	0.530	0.41
531_V	579_L	0.530	0.41
573_V	591_L	0.530	0.41
353_N	393_I	0.530	0.41
561_A	587_I	0.529	0.41
189_G	265_D	0.529	0.41
534_I	540_V	0.529	0.41
296_T	399_L	0.529	0.41
421_V	433_F	0.528	0.41
291_S	412_K	0.528	0.41
311_T	323_T	0.528	0.41
463_G	467_T	0.528	0.41
334_I	343_K	0.527	0.41
557_T	579_L	0.527	0.41
575_L	583_T	0.527	0.41
283_K	344_M	0.526	0.40
570_Y	639_I	0.525	0.40
298_L	304_L	0.524	0.40
175_K	263_G	0.524	0.40
536_L	721_G	0.524	0.40
153_Q	157_L	0.524	0.40
527_N	568_G	0.523	0.40
283_K	345_E	0.523	0.40
630_L	721_G	0.523	0.40
192_E	196_V	0.523	0.40
677_V	681_L	0.523	0.40
367_N	370_A	0.523	0.40
557_T	583_T	0.522	0.40
672_Q	675_E	0.522	0.40
588_S	621_G	0.522	0.40
217_E	220_F	0.522	0.40
751_G	754_I	0.522	0.40
237_G	265_D	0.521	0.40
171_R	262_F	0.521	0.40
336_N	405_N	0.521	0.40
145_E	148_I	0.521	0.40
401_Q	479_L	0.521	0.40
323_T	371_L	0.521	0.40
558_G	580_P	0.520	0.40
761_W	765_V	0.520	0.40
351_L	503_I	0.520	0.40
631_S	634_A	0.519	0.40
463_G	530_L	0.518	0.40
632_V	636_T	0.518	0.40
298_L	332_G	0.517	0.39
717_H	720_K	0.517	0.39
537_N	579_L	0.517	0.39
380_F	626_L	0.517	0.39
639_I	643_W	0.516	0.39
298_L	305_S	0.516	0.39
323_T	550_N	0.516	0.39
170_Y	242_F	0.515	0.39
167_L	240_A	0.515	0.39
746_W	750_V	0.514	0.39
304_L	534_I	0.514	0.39
487_I	501_L	0.514	0.39
558_G	583_T	0.514	0.39
155_S	159_S	0.513	0.39
300_G	313_L	0.513	0.39
181_N	245_R	0.513	0.39
321_L	324_I	0.512	0.39
170_Y	178_S	0.512	0.39
157_L	164_S	0.511	0.39
293_E	608_A	0.511	0.39
334_I	532_E	0.510	0.39
299_N	541_A	0.509	0.39
556_M	603_L	0.508	0.38
170_Y	263_G	0.508	0.38
283_K	296_T	0.508	0.38
205_S	226_L	0.507	0.38
308_L	400_R	0.507	0.38
588_S	591_L	0.506	0.38
161_L	188_T	0.506	0.38
595_Y	598_E	0.506	0.38
156_F	166_D	0.505	0.38
234_Y	259_L	0.504	0.38
579_L	610_V	0.504	0.38
183_A	188_T	0.504	0.38
532_E	570_Y	0.504	0.38
756_E	761_W	0.503	0.38
406_L	480_A	0.502	0.38
300_G	617_Y	0.502	0.38
471_I	475_V	0.502	0.38
698_S	702_S	0.502	0.38
165_P	187_L	0.502	0.38
177_F	229_E	0.501	0.38
249_Y	257_H	0.501	0.38
343_K	593_K	0.501	0.38
204_Y	213_I	0.500	0.38
154_S	170_Y	0.500	0.38
416_Q	506_P	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4gczA	2	0.4602	100	0.677	Contact Map
4i5sA	2	0.5026	100	0.684	Contact Map
3a0rA	2	0.4216	100	0.696	Contact Map
4r3aA	1	0.4023	100	0.73	Contact Map
2c2aA	2	0.2995	100	0.752	Contact Map
4mpcA	2	0.4177	100	0.752	Contact Map
4e01A	3	0.3805	100	0.756	Contact Map
2q8gA	2	0.4254	100	0.759	Contact Map
3jz3A	2	0.2057	100	0.762	Contact Map
4q20A	2	0.2956	100	0.762	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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