GREMLIN Database
YOAB - RutC family protein YoaB
UniProt: P0AEB7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13514
Length: 114 (106)
Sequences: 7427 (4619)
Seq/√Len: 448.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
40_A82_A3.0881.00
47_D57_K2.9661.00
34_D37_E2.6141.00
55_S59_S2.6111.00
36_F75_A2.3461.00
62_D109_K2.3181.00
36_F78_K2.2471.00
66_F95_V2.0311.00
40_A44_A1.9941.00
65_I76_M1.9441.00
46_I110_I1.9371.00
27_V104_Y1.8981.00
44_A83_W1.8091.00
38_Q105_K1.7981.00
96_Q99_L1.7911.00
72_D105_K1.7371.00
47_D51_E1.6951.00
70_K96_Q1.6491.00
41_N45_Q1.6041.00
30_N33_A1.5751.00
18_H61_L1.5391.00
63_A110_I1.5321.00
22_L55_S1.4671.00
18_H113_A1.4631.00
40_A83_W1.4521.00
56_N59_S1.4411.00
99_L103_K1.4261.00
28_P104_Y1.3841.00
44_A47_D1.3841.00
41_N44_A1.3821.00
50_L112_A1.3241.00
67_L76_M1.3171.00
35_A39_T1.2911.00
23_Y111_V1.2651.00
77_N92_R1.2551.00
68_A72_D1.2531.00
67_L94_T1.2391.00
22_L53_Q1.2171.00
60_I110_I1.1941.00
72_D75_A1.1791.00
79_A82_A1.1771.00
75_A78_K1.1681.00
93_C109_K1.1511.00
80_W92_R1.1381.00
17_I20_N1.1341.00
50_L55_S1.1101.00
85_V89_A1.0901.00
68_A99_L1.0851.00
64_T109_K1.0761.00
36_F40_A1.0611.00
39_T76_M1.0511.00
66_F97_A1.0511.00
26_G107_E1.0491.00
40_A79_A1.0481.00
17_I22_L1.0451.00
63_A80_W1.0211.00
21_T113_A1.0141.00
17_I55_S1.0071.00
66_F93_C0.9971.00
28_P42_T0.9911.00
47_D83_W0.9891.00
68_A105_K0.9771.00
24_Y49_V0.9761.00
85_V88_H0.9701.00
24_Y110_I0.9481.00
35_A76_M0.9411.00
60_I84_V0.9401.00
36_F79_A0.9381.00
66_F109_K0.9301.00
35_A72_D0.9211.00
21_T61_L0.8941.00
78_K81_D0.8791.00
15_V49_V0.8701.00
86_A89_A0.8551.00
43_L83_W0.8501.00
51_E56_N0.8371.00
69_D72_D0.8371.00
73_F94_T0.8231.00
71_N99_L0.8231.00
7_D52_K0.8161.00
78_K82_A0.8121.00
50_L60_I0.8051.00
63_A84_V0.8031.00
63_A108_I0.8031.00
37_E40_A0.7651.00
15_V53_Q0.7601.00
43_L108_I0.7561.00
68_A98_G0.7531.00
34_D75_A0.7521.00
14_D49_V0.7501.00
42_T46_I0.7471.00
57_K60_I0.7441.00
74_A78_K0.7391.00
68_A103_K0.7331.00
48_A51_E0.7321.00
43_L57_K0.7291.00
57_K83_W0.7281.00
101_N104_Y0.7241.00
11_R81_D0.7221.00
35_A79_A0.7171.00
79_A83_W0.7081.00
48_A52_K0.7071.00
30_N41_N0.7051.00
16_V91_V0.6951.00
24_Y46_I0.6941.00
20_N113_A0.6931.00
36_F82_A0.6901.00
58_S85_V0.6881.00
42_T108_I0.6861.00
15_V22_L0.6841.00
35_A75_A0.6831.00
45_Q48_A0.6821.00
39_T106_V0.6791.00
31_L41_N0.6711.00
62_D93_C0.6681.00
62_D111_V0.6661.00
35_A106_V0.6641.00
18_H23_Y0.6581.00
65_I92_R0.6501.00
81_D89_A0.6491.00
50_L57_K0.6481.00
64_T93_C0.6310.99
11_R77_N0.6300.99
21_T111_V0.6300.99
18_H21_T0.6270.99
68_A97_A0.6210.99
27_V42_T0.6100.99
64_T111_V0.6070.99
44_A48_A0.6070.99
70_K99_L0.6050.99
34_D105_K0.6010.99
28_P38_Q0.6000.99
43_L80_W0.5960.99
17_I53_Q0.5940.99
60_I63_A0.5850.99
77_N80_W0.5810.99
49_V52_K0.5770.99
65_I108_I0.5710.99
16_V61_L0.5680.99
25_T91_V0.5670.99
31_L48_A0.5660.99
69_D105_K0.5640.99
72_D96_Q0.5540.98
14_D52_K0.5520.98
74_A102_P0.5510.98
62_D91_V0.5470.98
24_Y93_C0.5380.98
69_D96_Q0.5370.98
13_S16_V0.5340.98
67_L70_K0.5310.98
29_E33_A0.5310.98
7_D14_D0.5240.98
14_D45_Q0.5240.98
67_L72_D0.5200.98
19_N113_A0.5190.98
58_S88_H0.5100.97
34_D38_Q0.5090.97
55_S113_A0.5020.97
73_F77_N0.5000.97
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3kjjA 3 0.9912 100 0.174 Contact Map
3k12A 3 0.9912 100 0.177 Contact Map
3gtzA 3 0.9825 100 0.201 Contact Map
3m1xA 3 0.9825 100 0.206 Contact Map
3r0pA 5 0.9912 100 0.208 Contact Map
1xrgA 3 0.9912 100 0.21 Contact Map
3l7qA 3 0.9912 100 0.21 Contact Map
2b33A 3 0.9912 100 0.211 Contact Map
3vczA 5 1 100 0.211 Contact Map
3quwA 3 0.9737 100 0.212 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0063 seconds.