CYSG - ECOLI - GREMLIN Contacts

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CYSG - Siroheme synthase

UniProt:	P0AEA8	Sequences: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10188
Length:	457 (447)
Sequences:	965 (657)
Seq/√Len:	31.1

ECOLI - CYSG
BACSU - NASF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
63_G	69_L	6.421	1.00
336_C	411_G	5.086	1.00
17_I	28_A	4.947	1.00
71_D	96_R	4.334	1.00
65_F	92_A	3.863	1.00
45_F	60_L	3.849	1.00
218_V	317_L	3.721	1.00
195_N	200_I	3.703	1.00
16_L	73_C	3.701	1.00
409_E	417_R	3.468	1.00
33_D	257_N	3.440	1.00
221_V	297_V	3.425	1.00
147_L	151_L	3.396	1.00
410_N	415_T	3.060	1.00
194_N	200_I	3.053	1.00
17_I	38_L	2.972	1.00
219_V	238_Q	2.894	1.00
28_A	49_F	2.801	1.00
246_V	289_E	2.756	1.00
288_R	292_K	2.701	1.00
138_L	184_V	2.664	1.00
194_N	199_A	2.651	1.00
4_L	113_M	2.638	1.00
245_V	259_V	2.598	1.00
284_Q	288_R	2.550	1.00
287_L	316_T	2.533	1.00
13_R	74_W	2.529	1.00
289_E	292_K	2.474	0.99
249_R	271_R	2.446	0.99
399_M	403_M	2.405	0.99
405_V	426_L	2.404	0.99
407_I	437_S	2.390	0.99
393_K	396_E	2.367	0.99
192_L	199_A	2.346	0.99
410_N	413_A	2.339	0.99
335_G	412_T	2.303	0.99
196_D	200_I	2.273	0.99
105_A	108_A	2.272	0.99
421_G	429_L	2.251	0.99
305_F	310_G	2.248	0.99
124_V	147_L	2.217	0.99
408_V	440_I	2.215	0.99
191_S	194_N	2.210	0.99
14_D	39_T	2.208	0.99
8_C	99_F	2.192	0.99
25_E	46_I	2.172	0.98
380_F	441_I	2.153	0.98
316_T	320_A	2.103	0.98
339_Y	416_Q	2.059	0.98
117_I	126_V	2.046	0.98
131_T	159_G	2.017	0.98
196_D	199_A	1.995	0.97
239_I	259_V	1.945	0.97
229_G	233_L	1.888	0.96
191_S	195_N	1.876	0.96
188_L	194_N	1.865	0.96
65_F	89_V	1.853	0.96
152_G	155_A	1.849	0.96
217_E	325_S	1.847	0.96
195_N	199_A	1.832	0.96
103_V	262_D	1.812	0.95
80_T	86_N	1.781	0.95
77_I	113_M	1.778	0.95
227_D	234_K	1.758	0.94
122_L	139_L	1.749	0.94
367_D	370_N	1.718	0.94
239_I	297_V	1.716	0.94
39_T	73_C	1.711	0.94
358_G	390_I	1.703	0.93
306_I	334_S	1.697	0.93
217_E	323_P	1.680	0.93
53_A	60_L	1.675	0.93
253_D	257_N	1.667	0.93
128_S	136_A	1.659	0.92
163_G	167_Q	1.657	0.92
37_R	59_T	1.640	0.92
291_Q	320_A	1.635	0.92
391_Q	395_I	1.631	0.92
3_H	9_Q	1.608	0.91
50_T	62_E	1.598	0.91
405_V	427_G	1.593	0.91
349_Y	446_G	1.593	0.91
217_E	295_R	1.582	0.91
122_L	128_S	1.581	0.91
41_N	69_L	1.580	0.90
28_A	58_L	1.577	0.90
90_S	94_E	1.571	0.90
3_H	112_I	1.571	0.90
189_A	194_N	1.559	0.90
88_R	92_A	1.546	0.89
46_I	49_F	1.544	0.89
287_L	320_A	1.532	0.89
376_Q	411_G	1.527	0.89
53_A	58_L	1.525	0.89
264_D	294_K	1.524	0.89
266_V	289_E	1.522	0.89
30_L	116_I	1.514	0.88
158_A	183_F	1.501	0.88
391_Q	427_G	1.497	0.88
426_L	429_L	1.493	0.88
421_G	425_Q	1.485	0.87
25_E	48_Q	1.480	0.87
387_A	426_L	1.480	0.87
191_S	200_I	1.476	0.87
428_E	432_Q	1.468	0.87
17_I	31_L	1.466	0.87
229_G	234_K	1.458	0.86
74_W	97_R	1.447	0.86
6_I	111_F	1.439	0.86
392_Q	396_E	1.436	0.86
104_D	109_A	1.434	0.86
188_L	195_N	1.427	0.85
18_V	89_V	1.424	0.85
289_E	294_K	1.423	0.85
52_W	57_M	1.396	0.84
221_V	239_I	1.387	0.84
126_V	139_L	1.385	0.83
195_N	198_K	1.377	0.83
190_Q	200_I	1.370	0.83
28_A	38_L	1.366	0.83
10_L	15_C	1.366	0.83
120_S	123_M	1.357	0.82
409_E	434_N	1.353	0.82
337_S	440_I	1.346	0.82
132_S	258_L	1.344	0.82
94_E	110_S	1.328	0.81
70_L	96_R	1.326	0.81
378_L	394_L	1.324	0.81
272_A	385_N	1.324	0.81
197_Q	200_I	1.323	0.81
92_A	96_R	1.298	0.79
349_Y	443_R	1.293	0.79
192_L	195_N	1.288	0.79
189_A	192_L	1.287	0.79
30_L	261_R	1.275	0.78
66_D	69_L	1.270	0.78
176_R	260_R	1.269	0.78
379_V	440_I	1.260	0.77
43_L	64_P	1.249	0.77
85_L	88_R	1.246	0.76
204_T	207_L	1.243	0.76
132_S	158_A	1.239	0.76
143_L	147_L	1.236	0.76
15_C	113_M	1.226	0.75
332_A	381_Y	1.223	0.75
348_D	361_K	1.220	0.75
190_Q	195_N	1.218	0.75
188_L	200_I	1.216	0.75
249_R	267_F	1.216	0.75
160_Q	200_I	1.215	0.74
150_H	153_Q	1.214	0.74
244_V	266_V	1.211	0.74
81_D	86_N	1.209	0.74
70_L	98_I	1.206	0.74
67_E	88_R	1.201	0.74
189_A	200_I	1.199	0.73
252_S	255_I	1.193	0.73
188_L	191_S	1.193	0.73
189_A	195_N	1.188	0.73
409_E	433_M	1.186	0.73
234_K	325_S	1.177	0.72
4_L	103_V	1.174	0.72
219_V	297_V	1.171	0.72
114_P	125_A	1.170	0.72
244_V	289_E	1.168	0.71
122_L	155_A	1.167	0.71
116_I	261_R	1.163	0.71
306_I	353_V	1.160	0.71
192_L	200_I	1.155	0.71
87_Q	91_E	1.153	0.70
395_I	402_E	1.151	0.70
331_T	334_S	1.148	0.70
389_T	392_Q	1.148	0.70
51_A	55_A	1.140	0.70
251_V	255_I	1.139	0.70
290_A	322_I	1.134	0.69
45_F	62_E	1.125	0.69
160_Q	201_T	1.118	0.68
384_L	437_S	1.117	0.68
301_G	310_G	1.111	0.68
191_S	199_A	1.110	0.68
354_R	370_N	1.108	0.67
247_Y	268_V	1.108	0.67
188_L	192_L	1.106	0.67
132_S	183_F	1.102	0.67
90_S	102_V	1.101	0.67
23_V	86_N	1.097	0.67
124_V	355_L	1.090	0.66
54_D	61_V	1.090	0.66
63_G	66_D	1.080	0.65
4_L	159_G	1.080	0.65
76_A	98_I	1.079	0.65
314_L	326_V	1.077	0.65
402_E	424_T	1.065	0.64
48_Q	52_W	1.060	0.64
85_L	89_V	1.056	0.64
401_G	424_T	1.053	0.63
119_R	144_E	1.048	0.63
29_R	265_R	1.047	0.63
20_G	49_F	1.044	0.63
246_V	286_L	1.044	0.63
79_A	86_N	1.035	0.62
179_W	358_G	1.035	0.62
210_E	319_N	1.032	0.62
28_A	63_G	1.030	0.62
18_V	76_A	1.024	0.61
90_S	109_A	1.021	0.61
39_T	59_T	1.017	0.61
121_P	331_T	1.008	0.60
32_L	57_M	1.008	0.60
386_Q	437_S	1.006	0.60
50_T	54_D	1.006	0.60
38_L	58_L	1.001	0.59
354_R	380_F	0.998	0.59
428_E	431_Q	0.992	0.59
128_S	131_T	0.990	0.59
23_V	80_T	0.980	0.58
219_V	295_R	0.976	0.57
200_I	203_T	0.976	0.57
384_L	433_M	0.974	0.57
90_S	110_S	0.968	0.57
197_Q	201_T	0.964	0.56
388_A	392_Q	0.963	0.56
353_V	380_F	0.962	0.56
354_R	376_Q	0.961	0.56
228_A	235_G	0.961	0.56
7_F	125_A	0.956	0.56
78_A	89_V	0.955	0.56
20_G	45_F	0.947	0.55
2_D	11_R	0.940	0.55
196_D	206_Q	0.939	0.54
324_F	339_Y	0.934	0.54
342_I	406_A	0.926	0.53
69_L	92_A	0.919	0.53
215_R	291_Q	0.915	0.53
138_L	142_K	0.910	0.52
354_R	378_L	0.908	0.52
17_I	24_A	0.907	0.52
231_L	235_G	0.907	0.52
102_V	185_N	0.906	0.52
25_E	52_W	0.903	0.52
112_I	245_V	0.902	0.51
249_R	336_C	0.900	0.51
443_R	446_G	0.897	0.51
121_P	152_G	0.891	0.51
3_H	439_I	0.891	0.51
87_Q	427_G	0.890	0.51
99_F	111_F	0.890	0.51
43_L	85_L	0.889	0.50
135_L	358_G	0.888	0.50
192_L	196_D	0.885	0.50
403_M	443_R	0.885	0.50
387_A	405_V	0.881	0.50
116_I	123_M	0.876	0.49
235_G	330_I	0.874	0.49
34_A	38_L	0.874	0.49
16_L	41_N	0.872	0.49
399_M	443_R	0.872	0.49
425_Q	429_L	0.871	0.49
271_R	274_Y	0.867	0.49
238_Q	325_S	0.867	0.49
409_E	435_S	0.867	0.49
165_V	365_E	0.866	0.49
188_L	196_D	0.864	0.48
176_R	261_R	0.863	0.48
78_A	86_N	0.861	0.48
79_A	103_V	0.859	0.48
360_L	379_V	0.857	0.48
8_C	125_A	0.857	0.48
187_R	191_S	0.854	0.48
9_Q	18_V	0.852	0.47
229_G	297_V	0.850	0.47
14_D	37_R	0.849	0.47
91_E	95_A	0.848	0.47
25_E	29_R	0.848	0.47
387_A	407_I	0.837	0.46
360_L	364_G	0.837	0.46
109_A	246_V	0.836	0.46
66_D	91_E	0.833	0.46
72_T	97_R	0.832	0.46
151_L	233_L	0.832	0.46
408_V	411_G	0.829	0.46
221_V	231_L	0.827	0.45
17_I	234_K	0.825	0.45
43_L	63_G	0.825	0.45
277_V	348_D	0.822	0.45
40_V	352_S	0.821	0.45
169_F	174_E	0.817	0.45
134_V	144_E	0.814	0.44
276_C	297_V	0.808	0.44
395_I	401_G	0.807	0.44
23_V	26_R	0.807	0.44
86_N	105_A	0.805	0.44
255_I	389_T	0.804	0.44
154_V	336_C	0.804	0.44
32_L	58_L	0.804	0.44
37_R	210_E	0.804	0.44
28_A	35_G	0.803	0.44
335_G	348_D	0.803	0.44
351_Q	361_K	0.803	0.44
7_F	367_D	0.802	0.43
379_V	413_A	0.800	0.43
156_K	160_Q	0.800	0.43
286_L	317_L	0.798	0.43
103_V	261_R	0.797	0.43
340_S	440_I	0.795	0.43
348_D	351_Q	0.787	0.42
359_H	368_W	0.785	0.42
33_D	139_L	0.782	0.42
223_A	255_I	0.780	0.42
182_L	187_R	0.779	0.42
125_A	152_G	0.778	0.42
343_P	445_V	0.776	0.41
21_G	80_T	0.774	0.41
91_E	427_G	0.772	0.41
273_G	276_C	0.772	0.41
2_D	120_S	0.772	0.41
311_G	346_H	0.771	0.41
65_F	70_L	0.770	0.41
2_D	9_Q	0.765	0.41
118_D	123_M	0.763	0.40
287_L	291_Q	0.760	0.40
12_D	131_T	0.760	0.40
15_C	36_A	0.758	0.40
406_A	411_G	0.756	0.40
104_D	230_L	0.756	0.40
74_W	99_F	0.753	0.40
247_Y	252_S	0.751	0.39
360_L	386_Q	0.751	0.39
370_N	373_A	0.751	0.39
124_V	143_L	0.749	0.39
134_V	262_D	0.749	0.39
283_N	286_L	0.748	0.39
128_S	274_Y	0.745	0.39
360_L	437_S	0.744	0.39
177_R	259_V	0.743	0.39
49_F	52_W	0.743	0.39
147_L	407_I	0.742	0.39
367_D	373_A	0.741	0.39
94_E	99_F	0.741	0.39
249_R	378_L	0.738	0.38
83_D	105_A	0.737	0.38
118_D	121_P	0.736	0.38
102_V	261_R	0.733	0.38
380_F	390_I	0.733	0.38
125_A	136_A	0.733	0.38
187_R	200_I	0.731	0.38
90_S	108_A	0.731	0.38
156_K	291_Q	0.731	0.38
310_G	343_P	0.731	0.38
249_R	354_R	0.731	0.38
40_V	164_R	0.730	0.38
50_T	60_L	0.730	0.38
330_I	340_S	0.729	0.38
417_R	433_M	0.728	0.38
57_M	396_E	0.728	0.38
187_R	195_N	0.726	0.38
387_A	421_G	0.726	0.38
278_P	412_T	0.725	0.37
39_T	58_L	0.718	0.37
134_V	180_E	0.717	0.37
272_A	386_Q	0.716	0.37
150_H	390_I	0.714	0.37
113_M	276_C	0.713	0.37
113_M	375_K	0.712	0.36
7_F	101_N	0.710	0.36
236_L	240_Q	0.709	0.36
83_D	107_K	0.709	0.36
45_F	53_A	0.708	0.36
17_I	365_E	0.706	0.36
43_L	441_I	0.704	0.36
356_I	441_I	0.702	0.36
310_G	346_H	0.698	0.35
91_E	170_A	0.697	0.35
407_I	413_A	0.696	0.35
346_H	351_Q	0.692	0.35
21_G	79_A	0.692	0.35
288_R	291_Q	0.691	0.35
34_A	77_I	0.691	0.35
22_D	30_L	0.690	0.35
238_Q	327_V	0.690	0.35
305_F	341_G	0.690	0.35
81_D	418_V	0.689	0.35
52_W	55_A	0.688	0.35
413_A	437_S	0.687	0.35
301_G	412_T	0.686	0.35
55_A	402_E	0.685	0.34
22_D	395_I	0.683	0.34
156_K	198_K	0.682	0.34
249_R	437_S	0.682	0.34
30_L	179_W	0.681	0.34
300_K	382_M	0.681	0.34
4_L	94_E	0.680	0.34
137_R	381_Y	0.679	0.34
190_Q	194_N	0.677	0.34
191_S	196_D	0.676	0.34
45_F	58_L	0.676	0.34
188_L	193_A	0.676	0.34
82_D	88_R	0.675	0.34
23_V	81_D	0.674	0.34
190_Q	199_A	0.673	0.34
247_Y	335_G	0.672	0.34
372_A	399_M	0.671	0.33
267_F	441_I	0.671	0.33
14_D	73_C	0.671	0.33
384_L	445_V	0.669	0.33
387_A	429_L	0.669	0.33
336_C	409_E	0.669	0.33
13_R	297_V	0.667	0.33
237_Q	337_S	0.667	0.33
391_Q	426_L	0.666	0.33
210_E	291_Q	0.665	0.33
253_D	256_M	0.665	0.33
236_L	421_G	0.662	0.33
49_F	53_A	0.661	0.33
339_Y	411_G	0.659	0.33
27_K	103_V	0.659	0.33
53_A	284_Q	0.658	0.33
228_A	234_K	0.658	0.33
111_F	367_D	0.657	0.32
144_E	261_R	0.655	0.32
311_G	377_T	0.655	0.32
128_S	183_F	0.653	0.32
87_Q	107_K	0.653	0.32
113_M	409_E	0.652	0.32
12_D	37_R	0.652	0.32
312_E	382_M	0.651	0.32
346_H	447_L	0.650	0.32
182_L	185_N	0.650	0.32
231_L	239_I	0.648	0.32
297_V	318_C	0.645	0.32
189_A	193_A	0.645	0.32
306_I	425_Q	0.645	0.32
343_P	406_A	0.645	0.32
27_K	381_Y	0.644	0.32
128_S	155_A	0.644	0.32
10_L	34_A	0.644	0.32
407_I	430_A	0.644	0.32
336_C	380_F	0.643	0.31
40_V	49_F	0.643	0.31
406_A	416_Q	0.643	0.31
259_V	335_G	0.641	0.31
282_I	316_T	0.640	0.31
417_R	434_N	0.638	0.31
309_R	312_E	0.638	0.31
124_V	254_D	0.637	0.31
41_N	71_D	0.637	0.31
351_Q	366_L	0.636	0.31
256_M	297_V	0.635	0.31
229_G	237_Q	0.634	0.31
34_A	92_A	0.634	0.31
194_N	234_K	0.633	0.31
110_S	223_A	0.632	0.31
41_N	288_R	0.632	0.31
212_L	291_Q	0.627	0.30
67_E	92_A	0.627	0.30
138_L	141_E	0.627	0.30
309_R	313_E	0.626	0.30
3_H	129_G	0.625	0.30
144_E	381_Y	0.623	0.30
6_I	113_M	0.621	0.30
238_Q	413_A	0.621	0.30
336_C	433_M	0.619	0.30
387_A	391_Q	0.619	0.30
34_A	255_I	0.619	0.30
107_K	415_T	0.613	0.29
4_L	30_L	0.613	0.29
284_Q	340_S	0.611	0.29
235_G	239_I	0.611	0.29
340_S	343_P	0.611	0.29
144_E	180_E	0.608	0.29
102_V	109_A	0.608	0.29
128_S	275_H	0.607	0.29
308_G	311_G	0.606	0.29
45_F	49_F	0.606	0.29
82_D	85_L	0.606	0.29
85_L	246_V	0.606	0.29
294_K	426_L	0.604	0.29
154_V	188_L	0.604	0.29
17_I	150_H	0.604	0.29
22_D	294_K	0.604	0.29
272_A	275_H	0.603	0.29
17_I	115_S	0.601	0.29
313_E	382_M	0.600	0.29
309_R	382_M	0.600	0.29
260_R	381_Y	0.599	0.28
48_Q	158_A	0.599	0.28
44_A	50_T	0.598	0.28
80_T	416_Q	0.598	0.28
337_S	381_Y	0.597	0.28
24_A	103_V	0.597	0.28
119_R	381_Y	0.596	0.28
41_N	65_F	0.595	0.28
97_R	122_L	0.595	0.28
147_L	183_F	0.595	0.28
279_Q	382_M	0.594	0.28
259_V	441_I	0.594	0.28
125_A	353_V	0.594	0.28
111_F	415_T	0.594	0.28
55_A	91_E	0.593	0.28
234_K	321_G	0.592	0.28
233_L	338_A	0.591	0.28
219_V	325_S	0.590	0.28
316_T	439_I	0.590	0.28
379_V	412_T	0.589	0.28
106_P	109_A	0.588	0.28
138_L	159_G	0.587	0.28
142_K	164_R	0.587	0.28
217_E	297_V	0.587	0.28
305_F	311_G	0.587	0.28
187_R	190_Q	0.586	0.28
285_I	289_E	0.586	0.28
211_P	424_T	0.585	0.28
21_G	86_N	0.584	0.28
3_H	16_L	0.584	0.28
12_D	35_G	0.583	0.27
50_T	319_N	0.583	0.27
387_A	425_Q	0.583	0.27
48_Q	218_V	0.583	0.27
105_A	109_A	0.582	0.27
90_S	131_T	0.582	0.27
176_R	262_D	0.582	0.27
396_E	408_V	0.582	0.27
80_T	89_V	0.581	0.27
161_L	239_I	0.581	0.27
118_D	137_R	0.579	0.27
102_V	108_A	0.579	0.27
51_A	291_Q	0.577	0.27
365_E	391_Q	0.577	0.27
238_Q	297_V	0.576	0.27
217_E	332_A	0.576	0.27
344_L	355_L	0.576	0.27
2_D	138_L	0.576	0.27
188_L	199_A	0.575	0.27
323_P	331_T	0.575	0.27
137_R	144_E	0.574	0.27
205_E	209_N	0.573	0.27
90_S	122_L	0.573	0.27
106_P	177_R	0.573	0.27
190_Q	203_T	0.572	0.27
330_I	362_T	0.572	0.27
201_T	206_Q	0.572	0.27
7_F	176_R	0.571	0.27
84_A	414_V	0.570	0.27
430_A	433_M	0.569	0.27
343_P	440_I	0.569	0.27
281_E	373_A	0.569	0.27
190_Q	193_A	0.568	0.26
388_A	407_I	0.568	0.26
38_L	92_A	0.568	0.26
350_A	377_T	0.567	0.26
44_A	210_E	0.567	0.26
298_R	347_R	0.567	0.26
193_A	200_I	0.565	0.26
34_A	126_V	0.565	0.26
7_F	17_I	0.564	0.26
61_V	210_E	0.564	0.26
177_R	430_A	0.563	0.26
300_K	309_R	0.562	0.26
429_L	432_Q	0.562	0.26
419_I	433_M	0.562	0.26
248_D	347_R	0.561	0.26
385_N	390_I	0.561	0.26
132_S	255_I	0.560	0.26
144_E	260_R	0.559	0.26
283_N	439_I	0.559	0.26
342_I	416_Q	0.558	0.26
198_K	201_T	0.557	0.26
179_W	344_L	0.557	0.26
260_R	344_L	0.557	0.26
257_N	261_R	0.557	0.26
125_A	331_T	0.557	0.26
300_K	312_E	0.555	0.26
159_G	166_K	0.555	0.26
248_D	298_R	0.554	0.26
408_V	418_V	0.553	0.26
151_L	219_V	0.552	0.26
122_L	211_P	0.551	0.25
190_Q	196_D	0.549	0.25
68_S	87_Q	0.548	0.25
291_Q	405_V	0.548	0.25
47_P	50_T	0.547	0.25
114_P	118_D	0.547	0.25
114_P	445_V	0.547	0.25
32_L	52_W	0.546	0.25
267_F	276_C	0.546	0.25
344_L	381_Y	0.546	0.25
16_L	98_I	0.545	0.25
39_T	255_I	0.545	0.25
318_C	324_F	0.544	0.25
349_Y	447_L	0.544	0.25
279_Q	357_T	0.544	0.25
424_T	428_E	0.543	0.25
203_T	206_Q	0.542	0.25
34_A	326_V	0.541	0.25
387_A	430_A	0.540	0.25
29_R	52_W	0.540	0.25
6_I	352_S	0.539	0.25
409_E	437_S	0.538	0.25
215_R	323_P	0.537	0.25
41_N	73_C	0.537	0.25
380_F	385_N	0.537	0.25
9_Q	285_I	0.535	0.24
114_P	152_G	0.535	0.24
54_D	167_Q	0.534	0.24
101_N	251_V	0.534	0.24
83_D	425_Q	0.533	0.24
361_K	366_L	0.533	0.24
157_Y	161_L	0.533	0.24
186_D	337_S	0.533	0.24
279_Q	300_K	0.532	0.24
343_P	377_T	0.529	0.24
300_K	313_E	0.529	0.24
277_V	282_I	0.529	0.24
167_Q	330_I	0.529	0.24
101_N	178_F	0.528	0.24
354_R	407_I	0.528	0.24
346_H	350_A	0.528	0.24
337_S	344_L	0.528	0.24
137_R	240_Q	0.527	0.24
16_L	65_F	0.525	0.24
129_G	418_V	0.525	0.24
228_A	301_G	0.525	0.24
109_A	435_S	0.525	0.24
198_K	389_T	0.525	0.24
327_V	331_T	0.524	0.24
37_R	53_A	0.524	0.24
273_G	297_V	0.523	0.24
109_A	180_E	0.522	0.24
335_G	368_W	0.522	0.24
17_I	292_K	0.521	0.24
3_H	334_S	0.521	0.24
246_V	361_K	0.521	0.24
185_N	194_N	0.519	0.24
399_M	408_V	0.518	0.23
25_E	45_F	0.517	0.23
352_S	390_I	0.514	0.23
33_D	118_D	0.513	0.23
212_L	428_E	0.513	0.23
182_L	191_S	0.513	0.23
354_R	390_I	0.512	0.23
417_R	432_Q	0.512	0.23
55_A	61_V	0.511	0.23
171_T	388_A	0.511	0.23
76_A	79_A	0.510	0.23
384_L	435_S	0.510	0.23
386_Q	407_I	0.510	0.23
248_D	313_E	0.509	0.23
352_S	383_G	0.509	0.23
89_V	92_A	0.508	0.23
167_Q	441_I	0.508	0.23
15_C	132_S	0.508	0.23
160_Q	164_R	0.508	0.23
189_A	199_A	0.508	0.23
281_E	304_P	0.507	0.23
115_S	259_V	0.507	0.23
40_V	61_V	0.506	0.23
13_R	110_S	0.505	0.23
301_G	351_Q	0.505	0.23
29_R	46_I	0.504	0.23
248_D	309_R	0.504	0.23
405_V	431_Q	0.504	0.23
300_K	345_T	0.504	0.23
189_A	196_D	0.503	0.23
44_A	143_L	0.503	0.23
291_Q	318_C	0.502	0.23
26_R	80_T	0.502	0.23
353_V	427_G	0.501	0.22
238_Q	241_Q	0.500	0.22
246_V	354_R	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pjqA	2	0.9934	100	0.302	Contact Map
2yboA	2	0.523	100	0.64	Contact Map
1s4dA	4	0.5536	100	0.644	Contact Map
1ve2A	2	0.4967	100	0.668	Contact Map
1va0A	2	0.488	100	0.681	Contact Map
1cbfA	2	0.512	100	0.682	Contact Map
4e16A	2	0.4902	100	0.682	Contact Map
3ndcA	2	0.5098	100	0.686	Contact Map
3i4tA	2	0.4967	100	0.705	Contact Map
1wyzA	2	0.4705	100	0.711	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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