CITT - ECOLI - GREMLIN Contacts

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CITT - Citrate carrier

UniProt:	P0AE74	Sequences: MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAMIVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSSTTVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDELKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITRYNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAHYLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13538
Length:	487 (407)
Sequences:	9028 (6035)
Seq/√Len:	299.2

ECOLI - CITT TTDT YBHI YFBS ARSB YFJV YBIR
BACSU - YFLS YWRK YDFA
HALSA - Q9HMC9
SULSO - Q980X8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
91_A	94_W	4.562	1.00
137_R	140_T	4.416	1.00
362_D	366_G	4.304	1.00
119_V	331_D	4.218	1.00
297_S	317_A	3.728	1.00
129_F	133_F	3.140	1.00
94_W	357_R	3.044	1.00
328_P	331_D	2.908	1.00
210_V	220_L	2.836	1.00
458_K	462_R	2.833	1.00
276_E	279_T	2.798	1.00
149_D	167_V	2.737	1.00
44_M	62_A	2.730	1.00
129_F	132_K	2.699	1.00
456_K	459_D	2.676	1.00
232_S	235_Q	2.651	1.00
293_L	317_A	2.584	1.00
376_S	379_A	2.565	1.00
38_F	360_F	2.541	1.00
35_W	39_A	2.453	1.00
108_F	342_L	2.428	1.00
288_W	292_G	2.277	1.00
195_M	449_I	2.271	1.00
459_D	462_R	2.245	1.00
293_L	320_L	2.215	1.00
150_I	244_G	2.214	1.00
116_G	321_M	2.208	1.00
291_I	295_L	2.197	1.00
112_I	318_V	2.184	1.00
139_L	256_Y	2.183	1.00
46_V	50_L	2.180	1.00
283_L	287_E	2.172	1.00
303_F	307_V	2.170	1.00
363_W	367_T	2.148	1.00
113_F	297_S	2.148	1.00
238_L	242_P	2.082	1.00
285_R	289_T	2.028	1.00
299_G	303_F	2.024	1.00
388_F	405_M	2.022	1.00
389_Y	468_G	2.009	1.00
353_N	357_R	1.995	1.00
283_L	286_R	1.974	1.00
196_W	200_I	1.946	1.00
330_K	333_T	1.915	1.00
145_I	171_I	1.898	1.00
469_V	473_S	1.872	1.00
171_I	198_M	1.870	1.00
109_G	318_V	1.869	1.00
125_R	129_F	1.847	1.00
43_A	47_G	1.837	1.00
40_V	65_I	1.833	1.00
296_L	300_L	1.818	1.00
116_G	290_L	1.815	1.00
234_L	238_L	1.810	1.00
47_G	58_I	1.790	1.00
63_V	96_L	1.779	1.00
47_G	50_L	1.768	1.00
40_V	62_A	1.748	1.00
427_L	479_G	1.748	1.00
385_V	431_S	1.746	1.00
375_F	379_A	1.746	1.00
109_G	314_G	1.715	1.00
367_T	371_H	1.695	1.00
237_F	241_L	1.692	1.00
386_L	472_I	1.687	1.00
204_L	247_L	1.686	1.00
235_Q	238_L	1.678	1.00
382_I	476_L	1.670	1.00
253_W	257_V	1.666	1.00
208_M	244_G	1.664	1.00
292_G	296_L	1.646	1.00
293_L	321_M	1.645	1.00
151_L	155_F	1.644	1.00
149_D	202_T	1.630	1.00
125_R	287_E	1.616	1.00
477_L	481_P	1.611	1.00
282_A	285_R	1.602	1.00
40_V	66_C	1.599	1.00
257_V	260_K	1.592	1.00
250_I	470_I	1.590	1.00
36_H	69_G	1.583	1.00
296_L	320_L	1.574	1.00
366_G	370_T	1.564	1.00
247_L	471_Y	1.556	1.00
303_F	306_E	1.555	1.00
284_T	287_E	1.555	1.00
146_V	201_S	1.549	1.00
94_W	97_A	1.538	1.00
378_N	480_W	1.525	1.00
211_T	233_W	1.514	1.00
40_V	69_G	1.513	1.00
34_A	360_F	1.500	1.00
108_F	112_I	1.498	1.00
115_L	118_E	1.497	1.00
66_C	354_G	1.490	1.00
143_Y	252_P	1.487	1.00
304_G	307_V	1.483	1.00
99_F	346_A	1.476	1.00
64_T	319_S	1.469	1.00
39_A	43_A	1.462	1.00
134_M	144_A	1.453	1.00
253_W	256_Y	1.445	1.00
245_V	249_I	1.441	1.00
277_L	280_M	1.414	1.00
65_I	69_G	1.393	1.00
104_V	342_L	1.390	1.00
478_V	482_I	1.386	1.00
53_I	58_I	1.384	1.00
275_D	278_K	1.381	1.00
37_Y	354_G	1.379	1.00
475_L	479_G	1.356	1.00
53_I	57_A	1.355	1.00
40_V	44_M	1.336	1.00
440_P	450_Y	1.331	1.00
461_W	465_A	1.327	1.00
235_Q	422_E	1.321	1.00
201_S	205_S	1.321	1.00
275_D	279_T	1.316	1.00
300_L	307_V	1.307	1.00
56_T	340_N	1.305	1.00
38_F	42_V	1.302	1.00
355_L	361_I	1.299	1.00
409_I	428_L	1.290	1.00
36_H	71_N	1.290	1.00
254_L	257_V	1.284	1.00
44_M	58_I	1.281	1.00
205_S	248_L	1.280	1.00
438_L	468_G	1.273	1.00
356_T	362_D	1.263	1.00
279_T	283_L	1.257	1.00
34_A	363_W	1.252	1.00
146_V	197_M	1.246	1.00
355_L	360_F	1.240	1.00
118_E	336_N	1.238	1.00
295_L	299_G	1.238	1.00
63_V	347_T	1.237	1.00
153_A	205_S	1.235	1.00
136_K	140_T	1.232	1.00
199_V	449_I	1.232	1.00
278_K	281_G	1.229	1.00
115_L	337_S	1.226	1.00
168_F	448_I	1.225	1.00
282_A	287_E	1.224	1.00
279_T	282_A	1.224	1.00
242_P	478_V	1.221	1.00
411_A	414_K	1.203	1.00
419_V	424_L	1.203	1.00
393_Y	398_L	1.194	1.00
135_G	140_T	1.193	1.00
286_R	289_T	1.192	1.00
43_A	65_I	1.189	1.00
282_A	286_R	1.188	1.00
158_S	161_A	1.175	1.00
41_F	355_L	1.174	1.00
416_I	419_V	1.174	1.00
390_F	395_F	1.169	1.00
293_L	300_L	1.157	1.00
241_L	245_V	1.156	1.00
132_K	274_G	1.155	1.00
145_I	174_L	1.154	1.00
394_L	468_G	1.146	1.00
208_M	241_L	1.136	1.00
281_G	287_E	1.134	1.00
283_L	288_W	1.125	1.00
48_M	59_S	1.116	1.00
458_K	461_W	1.116	1.00
54_P	58_I	1.113	1.00
146_V	251_A	1.108	1.00
385_V	427_L	1.106	1.00
477_L	480_W	1.105	1.00
124_R	128_L	1.102	1.00
465_A	469_V	1.098	1.00
277_L	283_L	1.094	1.00
410_L	414_K	1.083	1.00
138_T	193_Y	1.082	1.00
243_V	474_M	1.080	1.00
196_W	463_L	1.078	1.00
102_T	311_T	1.074	1.00
353_N	356_T	1.073	1.00
97_A	353_N	1.069	1.00
254_L	258_L	1.066	1.00
37_Y	66_C	1.059	1.00
386_L	390_F	1.057	1.00
115_L	336_N	1.055	1.00
67_V	95_G	1.054	1.00
250_I	474_M	1.054	1.00
150_I	248_L	1.053	1.00
60_F	343_V	1.050	1.00
402_T	433_G	1.049	1.00
277_L	281_G	1.047	1.00
254_L	470_I	1.040	1.00
154_P	208_M	1.032	1.00
246_I	474_M	1.031	1.00
259_Y	463_L	1.029	1.00
289_T	293_L	1.028	1.00
439_T	442_A	1.021	1.00
386_L	476_L	1.018	1.00
223_V	425_C	1.015	1.00
195_M	455_V	1.015	1.00
427_L	431_S	1.015	1.00
300_L	313_V	1.014	1.00
159_N	206_S	1.007	1.00
472_I	476_L	1.006	1.00
61_I	319_S	1.003	1.00
406_L	425_C	1.002	1.00
163_T	202_T	0.998	1.00
98_G	350_V	0.998	1.00
411_A	415_G	0.997	1.00
173_N	177_L	0.996	1.00
146_V	248_L	0.995	1.00
42_V	46_V	0.990	1.00
95_G	350_V	0.987	1.00
281_G	284_T	0.986	1.00
109_G	315_L	0.982	1.00
345_L	399_S	0.979	1.00
276_E	282_A	0.979	1.00
102_T	309_N	0.973	1.00
59_S	347_T	0.969	1.00
414_K	421_M	0.960	1.00
280_M	284_T	0.956	1.00
430_L	475_L	0.956	1.00
125_R	128_L	0.955	1.00
204_L	251_A	0.953	1.00
44_M	351_M	0.945	1.00
205_S	212_G	0.943	1.00
300_L	316_L	0.937	1.00
393_Y	436_G	0.932	1.00
384_L	428_L	0.931	1.00
309_N	312_A	0.930	1.00
169_P	173_N	0.924	1.00
175_P	194_L	0.924	1.00
107_V	399_S	0.922	1.00
117_Y	122_L	0.921	1.00
47_G	61_I	0.916	1.00
206_S	213_A	0.914	1.00
325_H	328_P	0.914	1.00
451_G	454_Y	0.907	1.00
372_L	383_V	0.904	1.00
464_G	467_F	0.901	1.00
281_G	285_R	0.899	1.00
440_P	447_V	0.896	1.00
363_W	366_G	0.896	1.00
279_T	285_R	0.896	1.00
388_F	431_S	0.890	1.00
329_W	333_T	0.890	1.00
61_I	64_T	0.890	1.00
473_S	477_L	0.889	1.00
101_S	221_E	0.888	1.00
290_L	294_V	0.880	1.00
394_L	442_A	0.880	1.00
333_T	343_V	0.879	1.00
292_G	295_L	0.876	1.00
195_M	198_M	0.874	1.00
280_M	283_L	0.873	1.00
397_S	400_A	0.873	1.00
48_M	58_I	0.873	1.00
240_F	430_L	0.869	1.00
91_A	95_G	0.868	1.00
290_L	293_L	0.865	1.00
438_L	465_A	0.865	1.00
213_A	216_N	0.863	1.00
208_M	237_F	0.862	1.00
370_T	373_E	0.855	1.00
301_W	314_G	0.854	1.00
328_P	332_I	0.854	1.00
391_A	401_H	0.854	1.00
59_S	63_V	0.849	1.00
438_L	461_W	0.848	1.00
63_V	67_V	0.847	1.00
308_I	313_V	0.845	1.00
139_L	252_P	0.845	1.00
266_S	269_V	0.844	1.00
466_I	469_V	0.843	1.00
459_D	463_L	0.843	1.00
394_L	438_L	0.842	1.00
390_F	468_G	0.841	1.00
219_G	429_V	0.837	1.00
73_L	357_R	0.835	1.00
61_I	65_I	0.835	1.00
215_P	443_T	0.834	1.00
147_I	151_L	0.834	1.00
255_S	259_Y	0.833	1.00
56_T	63_V	0.831	1.00
280_M	285_R	0.830	1.00
397_S	436_G	0.828	1.00
289_T	324_L	0.827	1.00
180_S	194_L	0.823	1.00
289_T	292_G	0.823	1.00
168_F	195_M	0.822	1.00
164_G	448_I	0.822	1.00
398_L	442_A	0.821	1.00
158_S	399_S	0.820	1.00
284_T	288_W	0.819	1.00
215_P	433_G	0.816	1.00
381_V	427_L	0.816	1.00
389_Y	472_I	0.811	1.00
203_S	437_C	0.811	1.00
142_G	194_L	0.811	1.00
436_G	442_A	0.808	1.00
66_C	351_M	0.804	1.00
214_A	399_S	0.801	1.00
124_R	276_E	0.796	1.00
73_L	91_A	0.795	1.00
218_L	406_L	0.793	0.99
293_L	301_W	0.791	0.99
243_V	247_L	0.789	0.99
257_V	261_P	0.784	0.99
44_M	48_M	0.782	0.99
277_L	285_R	0.781	0.99
55_A	58_I	0.779	0.99
199_V	446_G	0.777	0.99
66_C	71_N	0.776	0.99
233_W	237_F	0.771	0.99
215_P	399_S	0.771	0.99
55_A	59_S	0.770	0.99
71_N	354_G	0.770	0.99
398_L	436_G	0.768	0.99
393_Y	442_A	0.768	0.99
251_A	467_F	0.765	0.99
277_L	287_E	0.765	0.99
281_G	286_R	0.763	0.99
113_F	321_M	0.763	0.99
63_V	350_V	0.761	0.99
407_P	410_L	0.760	0.99
399_S	402_T	0.760	0.99
349_V	403_A	0.759	0.99
276_E	281_G	0.758	0.99
41_F	351_M	0.758	0.99
209_F	212_G	0.751	0.99
105_W	346_A	0.750	0.99
297_S	301_W	0.749	0.99
160_T	213_A	0.749	0.99
251_A	255_S	0.748	0.99
248_L	252_P	0.747	0.99
436_G	443_T	0.746	0.99
218_L	403_A	0.744	0.99
93_K	97_A	0.742	0.99
106_L	314_G	0.740	0.99
255_S	463_L	0.738	0.99
131_V	174_L	0.736	0.99
420_P	423_Q	0.736	0.99
246_I	478_V	0.736	0.99
316_L	319_S	0.736	0.99
215_P	402_T	0.736	0.99
365_A	369_S	0.734	0.99
367_T	370_T	0.734	0.99
216_N	236_W	0.733	0.99
294_V	301_W	0.732	0.99
207_S	244_G	0.730	0.99
62_A	66_C	0.730	0.99
274_G	279_T	0.730	0.99
37_Y	358_S	0.727	0.99
293_L	297_S	0.725	0.99
285_R	288_W	0.724	0.99
223_V	230_Q	0.724	0.99
368_M	387_V	0.723	0.99
104_V	346_A	0.722	0.99
399_S	444_G	0.722	0.99
222_F	406_L	0.718	0.99
249_I	253_W	0.718	0.99
406_L	410_L	0.717	0.99
250_I	254_L	0.716	0.99
210_V	237_F	0.715	0.99
301_W	304_G	0.715	0.99
236_W	429_V	0.714	0.99
92_L	312_A	0.713	0.99
387_V	391_A	0.713	0.99
120_S	290_L	0.712	0.99
327_V	332_I	0.711	0.99
98_G	353_N	0.710	0.99
152_L	162_R	0.710	0.99
148_I	167_V	0.710	0.99
54_P	57_A	0.709	0.99
300_L	304_G	0.707	0.99
171_I	194_L	0.707	0.99
367_T	372_L	0.706	0.99
282_A	288_W	0.705	0.99
41_F	44_M	0.702	0.99
206_S	209_F	0.701	0.99
199_V	445_P	0.700	0.99
153_A	159_N	0.699	0.99
220_L	230_Q	0.698	0.99
95_G	98_G	0.697	0.99
241_L	244_G	0.696	0.99
338_A	341_T	0.694	0.99
399_S	443_T	0.694	0.99
51_E	55_A	0.690	0.99
45_I	48_M	0.690	0.99
215_P	345_L	0.689	0.99
50_L	53_I	0.689	0.99
318_V	322_L	0.689	0.99
388_F	428_L	0.688	0.99
193_Y	261_P	0.685	0.99
242_P	245_V	0.679	0.98
204_L	248_L	0.678	0.98
297_S	300_L	0.676	0.98
382_I	386_L	0.674	0.98
463_L	466_I	0.673	0.98
371_H	374_G	0.671	0.98
210_V	217_V	0.670	0.98
276_E	280_M	0.670	0.98
233_W	236_W	0.670	0.98
197_M	201_S	0.668	0.98
377_P	381_V	0.668	0.98
380_T	384_L	0.667	0.98
254_L	466_I	0.666	0.98
67_V	312_A	0.665	0.98
280_M	286_R	0.664	0.98
163_T	449_I	0.664	0.98
437_C	446_G	0.663	0.98
218_L	399_S	0.662	0.98
426_I	430_L	0.662	0.98
444_G	447_V	0.661	0.98
382_I	472_I	0.660	0.98
115_L	119_V	0.660	0.98
298_L	302_V	0.660	0.98
288_W	291_I	0.659	0.98
237_F	242_P	0.654	0.98
162_R	202_T	0.654	0.98
236_W	426_I	0.654	0.98
219_G	425_C	0.652	0.98
92_L	95_G	0.652	0.98
160_T	206_S	0.648	0.98
203_S	445_P	0.647	0.98
33_Q	36_H	0.647	0.98
54_P	340_N	0.647	0.98
410_L	413_G	0.646	0.98
383_V	387_V	0.646	0.98
242_P	246_I	0.645	0.98
104_V	345_L	0.645	0.98
67_V	70_S	0.645	0.98
326_V	329_W	0.644	0.98
289_T	326_V	0.643	0.98
129_F	277_L	0.642	0.98
380_T	416_I	0.639	0.98
55_A	397_S	0.637	0.98
159_N	212_G	0.635	0.98
274_G	277_L	0.635	0.98
143_Y	249_I	0.633	0.98
153_A	206_S	0.633	0.98
219_G	406_L	0.632	0.98
163_T	445_P	0.631	0.97
206_S	434_I	0.630	0.97
110_A	314_G	0.630	0.97
378_N	382_I	0.629	0.97
279_T	287_E	0.629	0.97
57_A	61_I	0.628	0.97
223_V	229_I	0.628	0.97
280_M	287_E	0.628	0.97
385_V	475_L	0.626	0.97
447_V	450_Y	0.626	0.97
158_S	162_R	0.622	0.97
343_V	347_T	0.622	0.97
108_F	337_S	0.622	0.97
274_G	278_K	0.621	0.97
216_N	220_L	0.621	0.97
37_Y	71_N	0.620	0.97
146_V	252_P	0.619	0.97
110_A	297_S	0.617	0.97
410_L	425_C	0.616	0.97
355_L	404_T	0.616	0.97
205_S	209_F	0.615	0.97
279_T	286_R	0.614	0.97
239_C	478_V	0.614	0.97
359_G	362_D	0.611	0.97
274_G	282_A	0.611	0.97
468_G	471_Y	0.611	0.97
341_T	399_S	0.610	0.97
394_L	436_G	0.610	0.97
443_T	446_G	0.610	0.97
60_F	347_T	0.607	0.97
64_T	316_L	0.607	0.97
208_M	212_G	0.607	0.97
316_L	320_L	0.605	0.97
64_T	315_L	0.604	0.97
73_L	350_V	0.604	0.97
107_V	158_S	0.603	0.97
390_F	465_A	0.601	0.97
91_A	357_R	0.601	0.97
71_N	358_S	0.601	0.97
160_T	397_S	0.600	0.97
378_N	477_L	0.598	0.97
385_V	472_I	0.597	0.97
196_W	464_G	0.596	0.96
379_A	383_V	0.596	0.96
95_G	99_F	0.595	0.96
245_V	248_L	0.594	0.96
434_I	437_C	0.594	0.96
466_I	470_I	0.593	0.96
329_W	332_I	0.592	0.96
207_S	435_M	0.592	0.96
149_D	162_R	0.591	0.96
314_G	317_A	0.591	0.96
393_Y	397_S	0.589	0.96
95_G	100_S	0.588	0.96
242_P	482_I	0.587	0.96
232_S	241_L	0.587	0.96
375_F	380_T	0.586	0.96
151_L	154_P	0.586	0.96
154_P	209_F	0.585	0.96
243_V	478_V	0.585	0.96
124_R	177_L	0.584	0.96
423_Q	480_W	0.584	0.96
97_A	100_S	0.583	0.96
255_S	258_L	0.583	0.96
369_S	412_V	0.581	0.96
56_T	59_S	0.581	0.96
106_L	158_S	0.578	0.96
372_L	375_F	0.577	0.96
380_T	424_L	0.577	0.96
385_V	389_Y	0.576	0.96
145_I	149_D	0.576	0.96
153_A	212_G	0.576	0.96
229_I	235_Q	0.573	0.96
67_V	71_N	0.573	0.96
287_E	290_L	0.572	0.96
413_G	424_L	0.572	0.96
159_N	213_A	0.571	0.96
244_G	249_I	0.570	0.95
103_T	107_V	0.569	0.95
262_E	265_H	0.569	0.95
397_S	401_H	0.569	0.95
142_G	252_P	0.569	0.95
107_V	111_F	0.567	0.95
274_G	280_M	0.565	0.95
251_A	463_L	0.565	0.95
256_Y	259_Y	0.565	0.95
293_L	304_G	0.565	0.95
331_D	336_N	0.562	0.95
354_G	358_S	0.562	0.95
51_E	54_P	0.562	0.95
220_L	231_I	0.561	0.95
51_E	450_Y	0.561	0.95
215_P	398_L	0.561	0.95
92_L	96_L	0.558	0.95
139_L	143_Y	0.557	0.95
159_N	202_T	0.555	0.95
161_A	236_W	0.553	0.95
310_A	313_V	0.553	0.95
56_T	333_T	0.552	0.95
310_A	314_G	0.552	0.95
112_I	332_I	0.550	0.95
213_A	443_T	0.549	0.94
153_A	162_R	0.549	0.94
143_Y	256_Y	0.548	0.94
106_L	110_A	0.547	0.94
277_L	282_A	0.547	0.94
125_R	281_G	0.546	0.94
159_N	207_S	0.546	0.94
198_M	201_S	0.544	0.94
290_L	301_W	0.543	0.94
199_V	203_S	0.543	0.94
391_A	395_F	0.542	0.94
455_V	459_D	0.542	0.94
330_K	336_N	0.541	0.94
441_Y	457_S	0.541	0.94
219_G	402_T	0.540	0.94
127_A	174_L	0.540	0.94
246_I	470_I	0.539	0.94
249_I	252_P	0.538	0.94
142_G	193_Y	0.538	0.94
44_M	53_I	0.537	0.94
144_A	221_E	0.537	0.94
327_V	330_K	0.535	0.94
126_I	152_L	0.534	0.94
326_V	333_T	0.534	0.94
200_I	251_A	0.534	0.94
109_G	311_T	0.534	0.94
300_L	308_I	0.533	0.94
381_V	476_L	0.533	0.94
346_A	350_V	0.533	0.94
36_H	40_V	0.532	0.94
63_V	66_C	0.531	0.93
168_F	449_I	0.531	0.93
304_G	309_N	0.526	0.93
47_G	62_A	0.525	0.93
159_N	211_T	0.525	0.93
207_S	240_F	0.524	0.93
279_T	284_T	0.524	0.93
250_I	253_W	0.524	0.93
321_M	325_H	0.523	0.93
326_V	332_I	0.523	0.93
398_L	443_T	0.523	0.93
47_G	53_I	0.523	0.93
442_A	446_G	0.522	0.93
364_F	387_V	0.522	0.93
70_S	73_L	0.522	0.93
149_D	201_S	0.522	0.93
128_L	177_L	0.521	0.93
381_V	419_V	0.520	0.93
39_A	42_V	0.520	0.93
382_I	480_W	0.520	0.93
48_M	348_L	0.518	0.93
402_T	428_L	0.517	0.93
172_K	176_P	0.517	0.93
93_K	362_D	0.516	0.92
107_V	345_L	0.515	0.92
406_L	429_V	0.515	0.92
143_Y	147_I	0.514	0.92
141_L	174_L	0.511	0.92
333_T	340_N	0.510	0.92
290_L	297_S	0.509	0.92
130_L	144_A	0.507	0.92
445_P	449_I	0.506	0.92
36_H	39_A	0.506	0.92
413_G	416_I	0.505	0.92
285_R	290_L	0.503	0.92
409_I	412_V	0.503	0.92
37_Y	360_F	0.502	0.91
107_V	444_G	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f35D	2	0.8789	100	0.393	Contact Map
4r1iA	2	0.9097	100	0.665	Contact Map
4r0cA	3	0.8357	99.9	0.726	Contact Map
4pd6A	3	0.7433	31.7	0.963	Contact Map
2m20A	2	0.1232	22.2	0.966	Contact Map
3w9iA	3	0.3224	8.3	0.972	Contact Map
3giaA	1	0.4682	8	0.972	Contact Map
1ldfA	3	0.4661	6.4	0.973	Contact Map
2ksfA	1	0.2197	6.3	0.974	Contact Map
3qe7A	2	0.4949	6.1	0.974	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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