GREMLIN Database
ARTQ - Arginine ABC transporter permease protein ArtQ
UniProt: P0AE34 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11626
Length: 238 (204)
Sequences: 15302 (8964)
Seq/√Len: 627.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_V112_S3.3071.00
166_G223_L3.1241.00
138_G148_I2.9691.00
107_G179_V2.8231.00
200_E203_T2.7551.00
12_G16_G2.7011.00
191_T208_A2.6731.00
35_W47_G2.5921.00
32_F120_S2.4861.00
144_S147_A2.4341.00
134_Q156_Q2.2641.00
32_F116_A2.1451.00
36_E48_S2.1381.00
57_L62_V2.0911.00
139_Q148_I2.0571.00
221_Y225_R2.0441.00
135_W148_I2.0221.00
135_W139_Q1.9651.00
42_P46_A1.9021.00
13_M16_G1.8751.00
102_S105_L1.8731.00
146_S150_F1.8461.00
126_A161_A1.8411.00
42_P45_W1.8271.00
195_A201_P1.7861.00
37_S128_K1.7611.00
51_V120_S1.7411.00
20_C108_V1.7391.00
41_R45_W1.7291.00
17_L179_V1.7041.00
28_L116_A1.6961.00
16_G104_F1.6881.00
32_F47_G1.6871.00
191_T204_W1.6491.00
129_A160_H1.6411.00
11_A215_I1.6401.00
33_A123_L1.6271.00
18_A173_L1.6231.00
221_Y224_K1.6211.00
66_I110_A1.6111.00
217_L221_Y1.6101.00
8_A12_G1.5911.00
9_S12_G1.5791.00
13_M184_V1.5621.00
144_S148_I1.5441.00
213_L217_L1.5011.00
121_Q124_R1.4851.00
30_M123_L1.4851.00
145_K149_F1.4711.00
225_R228_L1.4561.00
189_L193_S1.4311.00
25_G115_Y1.4241.00
147_A151_R1.3961.00
119_A165_L1.3931.00
54_L113_L1.3331.00
63_V110_A1.2991.00
18_A176_T1.2951.00
190_Q193_S1.2851.00
147_A150_F1.2641.00
229_R232_R1.2591.00
40_W45_W1.2581.00
143_L147_A1.2581.00
6_P190_Q1.2521.00
45_W49_A1.2291.00
36_E121_Q1.2281.00
135_W153_V1.2261.00
62_V114_L1.2251.00
6_P9_S1.2181.00
124_R128_K1.2151.00
31_F35_W1.2131.00
24_V108_V1.2111.00
41_R44_A1.2061.00
37_S127_L1.1941.00
222_I225_R1.1901.00
22_L169_W1.1901.00
29_A119_A1.1881.00
185_N189_L1.1791.00
20_C112_S1.1691.00
16_G20_C1.1651.00
139_Q145_K1.1611.00
189_L192_K1.1571.00
104_F108_V1.1561.00
127_L153_V1.1501.00
50_L116_A1.1431.00
195_A205_Y1.1381.00
35_W43_V1.1371.00
44_A48_S1.1301.00
173_L215_I1.1131.00
11_A211_I1.1061.00
103_P183_S1.1051.00
138_G152_L1.0941.00
46_A49_A1.0861.00
123_L161_A1.0851.00
26_L165_L1.0761.00
49_A52_T1.0721.00
66_I106_C1.0631.00
47_G120_S1.0621.00
179_V186_D1.0551.00
52_T217_L1.0491.00
108_V112_S1.0481.00
57_L114_L1.0441.00
40_W43_V1.0421.00
39_K44_A1.0421.00
35_W38_A1.0321.00
203_T206_I1.0281.00
62_V66_I1.0251.00
54_L117_A1.0231.00
122_T168_Q1.0131.00
145_K148_I1.0111.00
192_K195_A1.0081.00
63_V178_L0.9981.00
194_I204_W0.9911.00
18_A169_W0.9771.00
46_A50_L0.9761.00
224_K228_L0.9671.00
9_S13_M0.9561.00
119_A168_Q0.9501.00
50_L54_L0.9501.00
52_T213_L0.9421.00
143_L151_R0.9411.00
130_V157_M0.9321.00
67_Y106_C0.9311.00
135_W145_K0.9291.00
28_L112_S0.9281.00
225_R229_R0.9271.00
149_F154_M0.9221.00
40_W46_A0.9211.00
171_V175_D0.9191.00
181_L185_N0.9181.00
101_V105_L0.9131.00
59_E114_L0.9111.00
173_L219_S0.9061.00
193_S197_R0.9061.00
177_A212_Y0.9061.00
5_F9_S0.9051.00
63_V179_V0.8991.00
105_L108_V0.8981.00
23_I27_A0.8961.00
67_Y182_I0.8951.00
21_A112_S0.8951.00
33_A37_S0.8821.00
105_L109_I0.8801.00
45_W48_S0.8801.00
149_F153_V0.8731.00
59_E175_D0.8681.00
14_T173_L0.8511.00
36_E51_V0.8501.00
64_L68_F0.8451.00
74_L99_F0.8411.00
21_A172_L0.8371.00
50_L117_A0.8351.00
115_Y168_Q0.8331.00
173_L216_T0.8271.00
218_L222_I0.8251.00
14_T212_Y0.8241.00
198_T201_P0.8231.00
185_N190_Q0.8181.00
38_A47_G0.8161.00
65_F69_G0.8131.00
187_L211_I0.8101.00
224_K227_D0.8091.00
122_T164_G0.8061.00
103_P184_V0.7991.00
11_A187_L0.7931.00
107_G182_I0.7921.00
33_A127_L0.7921.00
222_I226_I0.7901.00
188_M205_Y0.7871.00
214_V218_L0.7861.00
36_E44_A0.7861.00
133_G137_S0.7831.00
34_V149_F0.7801.00
160_H164_G0.7801.00
27_A31_F0.7761.00
48_S52_T0.7701.00
119_A123_L0.7701.00
111_L176_T0.7671.00
104_F184_V0.7671.00
17_L184_V0.7651.00
130_V160_H0.7621.00
179_V184_V0.7601.00
13_M186_D0.7591.00
22_L172_L0.7551.00
17_L176_T0.7531.00
132_V136_E0.7531.00
28_L32_F0.7511.00
30_M154_M0.7511.00
20_C24_V0.7491.00
188_M212_Y0.7461.00
25_G119_A0.7461.00
20_C104_F0.7461.00
115_Y175_D0.7461.00
17_L107_G0.7441.00
67_Y103_P0.7401.00
60_I181_L0.7371.00
9_S190_Q0.7311.00
70_S74_L0.7271.00
32_F35_W0.7231.00
127_L149_F0.7191.00
62_V110_A0.7131.00
132_V135_W0.7111.00
14_T18_A0.7071.00
19_V23_I0.7051.00
43_V46_A0.7041.00
36_E120_S0.7031.00
127_L157_M0.7001.00
111_L172_L0.6981.00
206_I210_A0.6901.00
5_F8_A0.6891.00
69_G73_L0.6841.00
35_W46_A0.6841.00
15_V19_V0.6821.00
180_S189_L0.6811.00
27_A112_S0.6741.00
32_F50_L0.6711.00
38_A145_K0.6691.00
115_Y119_A0.6681.00
60_I64_L0.6651.00
40_W44_A0.6651.00
54_L62_V0.6591.00
180_S183_S0.6571.00
65_F206_I0.6551.00
103_P182_I0.6551.00
130_V153_V0.6541.00
74_L101_V0.6531.00
53_I57_L0.6491.00
30_M158_W0.6491.00
191_T195_A0.6451.00
49_A53_I0.6421.00
35_W40_W0.6411.00
195_A204_W0.6401.00
219_S223_L0.6361.00
63_V182_I0.6351.00
210_A214_V0.6321.00
177_A180_S0.6271.00
24_V27_A0.6261.00
220_Q224_K0.6231.00
170_L219_S0.6201.00
26_L123_L0.6191.00
207_V211_I0.6151.00
153_V156_Q0.6111.00
6_P194_I0.6081.00
17_L21_A0.6071.00
27_A30_M0.6051.00
202_F206_I0.6031.00
188_M208_A0.6031.00
136_E151_R0.6031.00
13_M104_F0.6021.00
21_A111_L0.6001.00
15_V215_I0.5981.00
218_L225_R0.5941.00
144_S151_R0.5931.00
115_Y172_L0.5921.00
26_L169_W0.5911.00
7_L191_T0.5891.00
177_A188_M0.5871.00
66_I69_G0.5861.00
8_A211_I0.5851.00
197_R200_E0.5841.00
204_W208_A0.5831.00
208_A211_I0.5831.00
143_L148_I0.5811.00
17_L104_F0.5771.00
218_L221_Y0.5761.00
55_R121_Q0.5751.00
9_S16_G0.5691.00
8_A11_A0.5661.00
111_L179_V0.5651.00
63_V107_G0.5641.00
168_Q171_V0.5601.00
159_R230_A0.5591.00
183_S189_L0.5541.00
226_I230_A0.5471.00
213_L216_T0.5420.99
164_G167_N0.5420.99
135_W138_G0.5360.99
148_I153_V0.5360.99
162_L230_A0.5330.99
32_F36_E0.5320.99
170_L216_T0.5320.99
122_T161_A0.5320.99
18_A22_L0.5310.99
187_L212_Y0.5310.99
48_S51_V0.5300.99
39_K42_P0.5290.99
12_G15_V0.5280.99
7_L211_I0.5260.99
29_A123_L0.5200.99
70_S99_F0.5200.99
50_L113_L0.5190.99
123_L127_L0.5160.99
114_L175_D0.5160.99
221_Y228_L0.5140.99
194_I198_T0.5140.99
103_P106_C0.5130.99
7_L207_V0.5120.99
132_V139_Q0.5100.99
195_A198_T0.5070.99
29_A33_A0.5070.99
20_C23_I0.5060.99
162_L226_I0.5040.99
138_G141_L0.5020.99
131_P160_H0.5010.99
36_E47_G0.5000.99
32_F113_L0.5000.99
7_L194_I0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ymuD 2 0.8697 100 0.588 Contact Map
3tuiA 2 0.8697 99.9 0.644 Contact Map
2onkC 2 0.8908 99.9 0.663 Contact Map
3rlfF 1 0.9034 99.9 0.667 Contact Map
3d31C 2 0.8739 99.9 0.672 Contact Map
4tquM 1 0.9412 99.8 0.695 Contact Map
3rlfG 1 0.9118 99.8 0.696 Contact Map
4tquN 1 0.8529 99.7 0.735 Contact Map
2m8gX 1 0.2773 5.1 0.966 Contact Map
3e7lA 2 0.2647 5.1 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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