ARTM - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

ARTM - Arginine ABC transporter permease protein ArtM

UniProt:	P0AE30	Sequences: MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11627
Length:	222 (201)
Sequences:	15458 (8984)
Seq/√Len:	633.7

ECOLI - ARTM ARTQ HISQ GLTJ HISM YHDY GLTK YHDX GLNP YECS
BACSU - TCYM GLNM YCKA GLNP ARTQ YXEN TCYL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
152_S	208_M	3.263	1.00
25_V	99_S	3.229	1.00
94_A	165_A	3.223	1.00
177_S	193_A	2.989	1.00
125_C	135_T	2.973	1.00
121_Q	142_Y	2.771	1.00
13_H	17_T	2.714	1.00
131_S	134_D	2.703	1.00
36_I	48_V	2.677	1.00
58_T	63_Q	2.580	1.00
33_F	107_T	2.414	1.00
122_W	135_T	2.280	1.00
33_F	103_A	2.181	1.00
43_V	47_L	2.096	1.00
113_A	147_S	2.051	1.00
43_V	46_W	1.967	1.00
206_L	210_L	1.943	1.00
37_L	49_R	1.930	1.00
18_L	165_A	1.902	1.00
126_S	135_T	1.872	1.00
198_L	202_G	1.867	1.00
89_E	92_L	1.850	1.00
122_W	126_S	1.835	1.00
12_L	200_V	1.800	1.00
116_A	146_R	1.799	1.00
14_T	17_T	1.764	1.00
34_T	110_F	1.737	1.00
19_T	159_F	1.727	1.00
131_S	135_T	1.714	1.00
202_G	206_L	1.713	1.00
67_I	97_A	1.711	1.00
21_A	95_L	1.665	1.00
181_Y	187_V	1.661	1.00
177_S	189_V	1.659	1.00
33_F	48_V	1.631	1.00
52_I	107_T	1.623	1.00
17_T	91_W	1.601	1.00
206_L	209_R	1.591	1.00
108_Q	111_Y	1.586	1.00
38_T	115_R	1.584	1.00
106_T	151_Y	1.572	1.00
26_A	102_S	1.545	1.00
42_P	46_W	1.523	1.00
132_K	136_L	1.515	1.00
10_K	13_H	1.501	1.00
207_M	210_L	1.485	1.00
31_L	110_F	1.482	1.00
63_Q	101_N	1.466	1.00
29_L	103_A	1.458	1.00
14_T	170_L	1.458	1.00
210_L	213_R	1.455	1.00
9_M	13_H	1.443	1.00
41_T	46_W	1.422	1.00
42_P	45_V	1.410	1.00
38_T	114_I	1.401	1.00
58_T	101_N	1.376	1.00
91_W	95_L	1.333	1.00
32_I	36_I	1.331	1.00
122_W	139_L	1.316	1.00
130_M	134_D	1.310	1.00
37_L	108_Q	1.304	1.00
181_Y	190_F	1.288	1.00
55_F	100_L	1.277	1.00
126_S	132_K	1.243	1.00
175_G	179_L	1.237	1.00
114_I	139_L	1.232	1.00
36_I	39_L	1.211	1.00
64_I	97_A	1.200	1.00
90_P	169_T	1.194	1.00
19_T	162_T	1.191	1.00
23_L	155_V	1.187	1.00
21_A	99_S	1.181	1.00
176_Y	179_L	1.177	1.00
46_W	50_G	1.149	1.00
47_L	50_G	1.142	1.00
7_E	176_Y	1.128	1.00
109_L	154_E	1.125	1.00
25_V	95_L	1.123	1.00
175_G	178_Q	1.118	1.00
12_L	196_I	1.114	1.00
171_M	175_G	1.113	1.00
7_E	10_K	1.112	1.00
63_Q	67_I	1.109	1.00
134_D	137_A	1.109	1.00
159_F	200_V	1.108	1.00
67_I	93_C	1.106	1.00
30_A	106_T	1.098	1.00
27_L	151_Y	1.094	1.00
47_L	51_Y	1.085	1.00
53_T	202_G	1.081	1.00
17_T	21_A	1.062	1.00
22_S	99_S	1.061	1.00
207_M	211_I	1.059	1.00
165_A	172_E	1.055	1.00
110_F	147_S	1.054	1.00
53_T	198_L	1.053	1.00
111_Y	115_R	1.053	1.00
159_F	204_L	1.053	1.00
125_C	138_I	1.051	1.00
64_I	164_L	1.045	1.00
180_L	189_V	1.042	1.00
48_V	107_T	1.041	1.00
163_S	197_Y	1.038	1.00
36_I	44_L	1.036	1.00
19_T	155_V	1.031	1.00
136_L	140_L	1.021	1.00
106_T	154_E	1.021	1.00
50_G	53_T	1.012	1.00
117_I	146_R	1.002	1.00
95_L	99_S	1.001	1.00
15_S	159_F	0.998	1.00
157_L	161_S	0.995	1.00
203_L	207_M	0.984	1.00
209_R	212_E	0.978	1.00
60_L	101_N	0.972	1.00
55_F	104_A	0.964	1.00
210_L	214_K	0.962	1.00
41_T	44_L	0.955	1.00
37_L	52_I	0.955	1.00
184_T	187_V	0.947	1.00
209_R	213_R	0.946	1.00
64_I	165_A	0.942	1.00
94_A	168_I	0.941	1.00
66_L	70_G	0.931	1.00
65_F	69_Y	0.928	1.00
39_L	48_V	0.925	1.00
106_T	110_F	0.924	1.00
120_G	124_S	0.915	1.00
136_L	139_L	0.915	1.00
15_S	197_Y	0.914	1.00
45_V	49_R	0.913	1.00
29_L	99_S	0.904	1.00
133_K	137_A	0.897	1.00
40_K	45_V	0.890	1.00
132_K	135_T	0.890	1.00
37_L	45_V	0.885	1.00
92_L	96_I	0.877	1.00
159_F	201_N	0.868	1.00
146_R	150_S	0.865	1.00
102_S	154_E	0.860	1.00
60_L	161_S	0.859	1.00
91_W	170_L	0.857	1.00
117_I	143_A	0.851	1.00
178_Q	181_Y	0.851	1.00
34_T	38_T	0.850	1.00
92_L	95_L	0.847	1.00
51_Y	104_A	0.842	1.00
51_Y	103_A	0.841	1.00
24_I	28_I	0.841	1.00
21_A	25_V	0.838	1.00
174_M	197_Y	0.837	1.00
85_H	88_S	0.836	1.00
20_V	24_I	0.833	1.00
68_Y	93_C	0.831	1.00
179_L	183_R	0.830	1.00
10_K	14_T	0.827	1.00
21_A	91_W	0.826	1.00
28_I	32_I	0.815	1.00
63_Q	97_A	0.813	1.00
51_Y	55_F	0.806	1.00
68_Y	168_I	0.798	1.00
90_P	170_L	0.796	1.00
34_T	114_I	0.788	1.00
119_E	123_Q	0.787	1.00
18_L	162_T	0.780	1.00
199_V	203_L	0.779	1.00
174_M	190_F	0.778	1.00
120_G	123_Q	0.774	1.00
181_Y	189_V	0.773	1.00
23_L	158_V	0.773	1.00
122_W	132_K	0.766	1.00
189_V	193_A	0.764	1.00
41_T	47_L	0.761	1.00
46_W	49_R	0.761	1.00
102_S	161_S	0.760	1.00
114_I	143_A	0.759	1.00
165_A	170_L	0.755	1.00
16_L	20_V	0.747	1.00
12_L	173_V	0.745	1.00
49_R	53_T	0.742	1.00
167_T	171_M	0.742	1.00
18_L	94_A	0.731	1.00
171_M	176_Y	0.730	1.00
90_P	168_I	0.729	1.00
14_T	172_E	0.724	1.00
66_L	191_G	0.724	1.00
98_L	162_T	0.723	1.00
41_T	45_V	0.720	1.00
6_P	10_K	0.716	1.00
156_V	204_L	0.713	1.00
177_S	181_Y	0.710	1.00
109_L	150_S	0.708	1.00
29_L	33_F	0.707	1.00
98_L	158_V	0.706	1.00
57_G	160_K	0.704	1.00
166_Y	169_T	0.703	1.00
174_M	193_A	0.703	1.00
195_I	199_V	0.699	1.00
154_E	157_L	0.697	1.00
163_S	166_Y	0.696	1.00
18_L	170_L	0.693	1.00
163_S	174_M	0.685	1.00
166_Y	175_G	0.681	1.00
101_N	154_E	0.681	1.00
15_S	19_T	0.679	1.00
25_V	28_I	0.679	1.00
191_G	195_I	0.678	1.00
117_I	139_L	0.677	1.00
26_A	106_T	0.676	1.00
22_S	158_V	0.671	1.00
173_V	196_I	0.670	1.00
119_E	122_W	0.665	1.00
98_L	165_A	0.657	1.00
88_S	93_C	0.657	1.00
68_Y	90_P	0.657	1.00
31_L	144_F	0.655	1.00
88_S	92_L	0.654	1.00
31_L	140_L	0.653	1.00
61_L	167_T	0.650	1.00
44_L	47_L	0.646	1.00
198_L	201_N	0.645	1.00
37_L	107_T	0.645	1.00
102_S	106_T	0.644	1.00
35_I	136_L	0.644	1.00
33_F	36_I	0.641	1.00
40_K	43_V	0.639	1.00
6_P	9_M	0.639	1.00
28_I	99_S	0.639	1.00
36_I	47_L	0.638	1.00
55_F	63_Q	0.634	1.00
36_I	41_T	0.631	1.00
39_L	132_K	0.630	1.00
192_A	196_I	0.621	1.00
99_S	103_A	0.616	1.00
101_N	161_S	0.612	1.00
193_A	196_I	0.612	1.00
135_T	139_L	0.609	1.00
114_I	136_L	0.605	1.00
8_L	177_S	0.604	1.00
139_L	142_Y	0.594	1.00
203_L	210_L	0.593	1.00
180_L	184_T	0.591	1.00
50_G	54_L	0.589	1.00
27_L	110_F	0.589	1.00
39_L	42_P	0.582	1.00
67_I	70_G	0.581	1.00
33_F	51_Y	0.577	1.00
102_S	158_V	0.575	1.00
183_R	186_D	0.574	1.00
49_R	52_I	0.573	1.00
61_L	65_F	0.573	1.00
112_G	150_S	0.572	1.00
211_I	215_A	0.572	1.00
203_L	206_L	0.567	1.00
150_S	153_N	0.566	1.00
14_T	91_W	0.565	1.00
56_T	108_Q	0.562	1.00
61_L	164_L	0.558	1.00
122_W	136_L	0.555	1.00
148_L	211_I	0.554	1.00
196_I	200_V	0.553	1.00
44_L	48_V	0.550	1.00
64_I	98_L	0.548	1.00
19_T	23_L	0.548	1.00
10_K	176_Y	0.546	1.00
188_M	191_G	0.545	1.00
118_P	146_R	0.540	0.99
13_H	16_L	0.540	0.99
204_L	208_M	0.539	0.99
190_F	193_A	0.539	0.99
16_L	200_V	0.537	0.99
18_L	22_S	0.537	0.99
130_M	135_T	0.535	0.99
40_K	132_K	0.534	0.99
122_W	125_C	0.533	0.99
8_L	192_A	0.532	0.99
35_I	39_L	0.532	0.99
33_F	37_L	0.530	0.99
25_V	29_L	0.527	0.99
21_A	24_I	0.526	0.99
8_L	196_I	0.524	0.99
17_T	95_L	0.523	0.99
54_L	58_T	0.523	0.99
155_V	204_L	0.523	0.99
8_L	180_L	0.522	0.99
30_A	110_F	0.522	0.99
10_K	17_T	0.519	0.99
143_A	147_S	0.519	0.99
173_V	197_Y	0.517	0.99
28_I	31_L	0.517	0.99
64_I	94_A	0.517	0.99
9_M	196_I	0.515	0.99
11_G	176_Y	0.514	0.99
205_T	209_R	0.514	0.99
8_L	176_Y	0.513	0.99
64_I	168_I	0.511	0.99
177_S	190_F	0.510	0.99
145_K	215_A	0.508	0.99
60_L	63_Q	0.505	0.99
65_F	190_F	0.504	0.99
125_C	128_L	0.501	0.99
7_E	180_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ymuD	2	0.9279	100	0.591	Contact Map
3tuiA	2	0.9324	99.9	0.645	Contact Map
2onkC	2	0.9459	99.9	0.665	Contact Map
3rlfF	1	0.9279	99.9	0.669	Contact Map
3d31C	2	0.9324	99.8	0.674	Contact Map
4tquM	1	0.973	99.8	0.691	Contact Map
3rlfG	1	0.973	99.8	0.708	Contact Map
4tquN	1	0.9054	99.7	0.735	Contact Map
4cbcA	3	0.4144	14	0.957	Contact Map
4ltoA	3	0.4685	13.3	0.958	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0083 seconds.