GREMLIN Database
YAJC - UPF0092 membrane protein YajC
UniProt: P0ADZ7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11096
Length: 110 (91)
Sequences: 2381 (1625)
Seq/√Len: 170.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
85_L91_V2.5661.00
51_K55_S2.4681.00
34_F38_I2.1371.00
48_E51_K2.1271.00
27_L31_G2.0351.00
44_K48_E2.0121.00
49_H53_M2.0081.00
33_I37_M1.9521.00
69_V94_K1.8951.00
24_I28_V1.8781.00
50_K54_D1.7841.00
51_K54_D1.7781.00
82_A90_E1.7451.00
68_L91_V1.7341.00
21_M26_M1.6411.00
56_I98_V1.5771.00
86_N89_T1.5541.00
29_V32_L1.5391.00
43_Q47_K1.5211.00
62_V83_I1.5181.00
56_I72_V1.5171.00
46_T50_K1.5161.00
45_R48_E1.5111.00
21_M25_L1.4991.00
27_L30_F1.4811.00
65_N97_F1.4661.00
43_Q46_T1.4441.00
22_S26_M1.4381.00
28_V32_L1.4051.00
61_E71_R1.3631.00
20_P23_L1.2911.00
52_L101_V1.2901.00
31_G39_L1.2891.00
25_L29_V1.2721.00
82_A92_V1.2711.00
68_L85_L1.2301.00
20_P24_I1.2191.00
69_V80_Y1.2141.00
81_I98_V1.2101.00
30_F34_F1.2101.00
19_S22_S1.1681.00
40_R44_K1.1411.00
23_L27_L1.1361.00
22_S25_L1.1151.00
26_M29_V1.1051.00
73_T90_E1.0851.00
85_L89_T1.0831.00
19_S23_L1.0801.00
75_V95_R1.0631.00
31_G34_F1.0581.00
57_A60_D1.0490.99
69_V74_K1.0390.99
26_M30_F1.0380.99
42_Q46_T1.0300.99
68_L93_I1.0030.99
70_G83_I0.9540.99
65_N99_A0.9420.99
29_V33_I0.9280.99
71_R84_A0.9230.99
45_R49_H0.9020.98
84_A88_T0.8960.98
23_L26_M0.8830.98
94_K97_F0.8790.98
80_Y92_V0.8780.98
64_T83_I0.8770.98
36_F40_R0.8700.98
83_I93_I0.8550.98
84_A90_E0.8460.98
63_L69_V0.8440.98
56_I75_V0.8380.97
39_L43_Q0.8370.97
94_K100_A0.8350.97
38_I43_Q0.8320.97
46_T49_H0.8290.97
69_V102_L0.8040.97
84_A87_D0.8000.97
52_L55_S0.7950.96
87_D90_E0.7840.96
58_K74_K0.7830.96
84_A92_V0.7750.96
76_A92_V0.7720.96
49_H65_N0.7440.95
27_L34_F0.7420.95
49_H52_L0.7410.95
61_E102_L0.7310.94
24_I27_L0.7080.93
17_Q20_P0.6970.93
57_A104_K0.6950.93
64_T93_I0.6940.93
18_G22_S0.6900.92
63_L100_A0.6890.92
66_G93_I0.6780.92
73_T84_A0.6760.92
63_L102_L0.6740.92
85_L93_I0.6700.91
58_K73_T0.6700.91
40_R48_E0.6690.91
32_L36_F0.6640.91
82_A87_D0.6510.90
72_V75_V0.6450.90
27_L32_L0.6350.89
57_A103_P0.6300.89
22_S29_V0.6190.88
40_R43_Q0.6180.88
80_Y94_K0.6090.87
86_N90_E0.5920.85
62_V98_V0.5870.85
93_I97_F0.5840.85
30_F33_I0.5840.85
73_T82_A0.5690.83
76_A80_Y0.5650.83
76_A82_A0.5640.83
29_V38_I0.5630.82
72_V101_V0.5560.82
69_V92_V0.5550.82
78_N103_P0.5530.81
81_I93_I0.5510.81
52_L60_D0.5490.81
86_N91_V0.5440.80
65_N96_D0.5430.80
74_K82_A0.5400.80
64_T98_V0.5370.79
42_Q49_H0.5360.79
61_E94_K0.5350.79
87_D92_V0.5330.79
65_N93_I0.5290.78
36_F44_K0.5260.78
84_A89_T0.5240.78
82_A86_N0.5210.77
15_P18_G0.5170.77
30_F39_L0.5170.77
61_E104_K0.5130.76
52_L99_A0.5060.75
21_M24_I0.5050.75
35_Y82_A0.5040.75
77_E95_R0.5000.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2rddB 1 0.3364 99.3 0.649 Contact Map
4hczA 1 0.4818 73.3 0.893 Contact Map
4l5gA 1 0.5364 65.5 0.899 Contact Map
4hw9A 3 0.8 61.4 0.901 Contact Map
3udcA 3 0.8545 61.2 0.901 Contact Map
5ajiA 3 0.8 53.1 0.906 Contact Map
1zq1A 2 0.5727 35.8 0.915 Contact Map
2lwjA 1 0.5636 32.3 0.917 Contact Map
2k4kA 1 0.4727 31.5 0.918 Contact Map
2xdpA 2 0.4545 30.8 0.918 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.005 seconds.