GREMLIN Database
RS15 - 30S ribosomal protein S15
UniProt: P0ADZ4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10914
Length: 89 (87)
Sequences: 2581 (1091)
Seq/√Len: 117.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
14_E84_R3.9921.00
35_Q59_M3.3111.00
7_A10_K2.8151.00
7_A34_A2.7661.00
75_V79_T2.6421.00
26_E77_R2.5851.00
80_Q84_R2.2091.00
13_S16_G2.1301.00
10_K14_E2.0051.00
17_R21_D1.9321.00
74_D77_R1.8901.00
34_A38_H1.8431.00
41_G44_A1.7751.00
50_H53_R1.7411.00
15_F84_R1.7141.00
33_T37_N1.6881.00
16_G20_N1.6441.00
76_A80_Q1.5641.00
54_R58_R1.5231.00
29_V81_L1.4891.00
53_R57_L1.4301.00
78_Y82_I1.4181.00
4_S7_A1.4101.00
34_A37_N1.3741.00
7_A38_H1.3221.00
64_R68_D1.3121.00
5_T9_A1.3111.00
57_L60_V1.2911.00
68_D71_K1.2851.00
9_A13_S1.2070.99
12_V27_V1.2000.99
80_Q83_E1.1730.99
57_L61_S1.1660.99
43_F61_S1.1210.99
68_D72_R1.1170.99
3_L38_H1.0820.98
52_S55_G1.0690.98
51_H55_G1.0630.98
13_S19_A1.0530.98
50_H61_S1.0410.98
3_L31_L1.0340.98
61_S65_K1.0240.98
58_R65_K1.0230.98
77_R80_Q1.0110.97
43_F50_H0.9930.97
25_T77_R0.9910.97
16_G19_A0.9660.96
82_I87_L0.9620.96
21_D27_V0.9500.96
82_I86_G0.9340.96
17_R26_E0.8980.95
56_L60_V0.8540.93
40_Q43_F0.8510.93
70_L77_R0.8470.93
43_F53_R0.8430.93
77_R81_L0.8420.93
40_Q44_A0.8340.92
43_F52_S0.8270.92
25_T70_L0.8160.91
44_A47_K0.8060.91
12_V31_L0.8060.91
7_A14_E0.7990.91
16_G24_S0.7910.90
76_A79_T0.7900.90
10_K13_S0.7760.89
11_I31_L0.7710.89
27_V32_L0.7600.88
68_D89_R0.7500.88
58_R62_Q0.7500.88
32_L62_Q0.7410.87
35_Q38_H0.7380.87
46_H51_H0.7340.87
29_V67_L0.7310.86
9_A12_V0.7240.86
26_E70_L0.7190.85
21_D24_S0.7160.85
15_F30_A0.7070.84
43_F71_K0.7010.84
41_G45_E0.7000.84
21_D25_T0.6960.83
32_L59_M0.6930.83
79_T83_E0.6920.83
37_N40_Q0.6830.82
8_T12_V0.6710.81
70_L73_K0.6700.81
5_T89_R0.6600.80
65_K68_D0.6590.80
40_Q64_R0.6540.80
35_Q40_Q0.6540.80
46_H54_R0.6440.78
43_F54_R0.6410.78
45_E48_K0.6400.78
29_V82_I0.6370.78
29_V70_L0.6300.77
26_E81_L0.6280.77
29_V66_L0.6260.77
17_R25_T0.6220.76
58_R61_S0.6180.76
32_L51_H0.6080.74
21_D30_A0.6040.74
85_L88_R0.5950.73
15_F81_L0.5900.72
43_F58_R0.5870.72
40_Q56_L0.5840.71
27_V31_L0.5740.70
37_N56_L0.5700.70
53_R89_R0.5630.69
6_E9_A0.5610.68
71_K75_V0.5600.68
35_Q62_Q0.5470.67
44_A87_L0.5390.65
11_I34_A0.5390.65
27_V30_A0.5360.65
11_I15_F0.5350.65
25_T29_V0.5350.65
22_T27_V0.5340.65
3_L35_Q0.5330.65
62_Q65_K0.5310.64
37_N41_G0.5290.64
79_T82_I0.5190.62
43_F65_K0.5180.62
22_T30_A0.5160.62
58_R89_R0.5140.62
36_I60_V0.5130.62
29_V77_R0.5110.61
31_L35_Q0.5080.61
8_T11_I0.5070.61
32_L55_G0.5050.60
3_L40_Q0.5010.60
25_T66_L0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5O 1 0.9888 100 0.064 Contact Map
4iylA 3 0.9551 100 0.07 Contact Map
1a32A 1 0.9551 100 0.083 Contact Map
4a5uB 1 0.8989 100 0.089 Contact Map
5aj3O 1 1 100 0.112 Contact Map
3bbnO 1 0.9326 100 0.191 Contact Map
3j20Q 1 0.9551 99.9 0.387 Contact Map
4ujpO 1 0.9888 99.4 0.597 Contact Map
3zeyG 1 0.8876 99.4 0.602 Contact Map
4bpeO 1 0.9888 99.4 0.602 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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