GREMLIN Database
RL14 - 50S ribosomal protein L14
UniProt: P0ADY3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10875
Length: 123 (122)
Sequences: 1575 (587)
Seq/√Len: 53.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_I58_L4.8531.00
19_V84_C4.1411.00
21_C39_I3.7481.00
19_V41_I3.1921.00
7_M18_R2.9971.00
5_Q20_M2.7061.00
20_M44_K2.5741.00
60_A84_C2.5171.00
2_I21_C2.4711.00
25_L40_K2.3201.00
18_R45_E2.1811.00
70_R76_V2.1621.00
40_K59_K2.1031.00
90_N93_Q2.0021.00
33_A62_V1.9811.00
19_V43_I1.9321.00
42_T55_G1.8870.99
51_K95_I1.8550.99
88_N93_Q1.8280.99
9_N81_G1.8250.99
7_M20_M1.7940.99
86_L95_I1.7930.99
10_V19_V1.7730.99
107_L116_I1.7360.99
34_G69_V1.7250.99
4_E23_K1.6220.98
59_K89_N1.5910.98
9_N18_R1.5840.98
20_M42_T1.5640.98
34_G68_G1.5560.98
2_I6_T1.5450.98
71_R106_E1.5020.97
77_I123_L1.4320.96
38_I112_F1.3510.95
7_M44_K1.2640.93
95_I109_S1.2530.92
35_V69_V1.2350.92
103_V107_L1.1990.91
92_E111_K1.1900.90
38_I87_L1.1680.89
92_E112_F1.1650.89
114_K117_S1.1590.89
10_V84_C1.1510.89
113_M116_I1.1180.87
4_E20_M1.1140.87
8_L19_V1.0970.86
83_A109_S1.0910.86
50_G55_G1.0890.86
3_Q6_T1.0850.86
108_R113_M1.0820.85
22_I123_L1.0660.84
23_K29_H1.0590.84
39_I62_V1.0560.84
63_V103_V1.0450.83
24_V33_A1.0360.83
2_I8_L1.0140.81
19_V62_V0.9580.78
64_R83_A0.9540.77
14_S95_I0.9510.77
103_V115_I0.9300.75
64_R101_G0.9230.75
53_K56_D0.9100.74
11_A102_P0.9020.73
64_R81_G0.8920.72
35_V68_G0.8670.70
60_A86_L0.8640.70
68_G76_V0.8580.69
45_E102_P0.8470.68
18_R44_K0.8470.68
71_R74_G0.8440.68
116_I123_L0.8420.68
63_V85_V0.8420.68
11_A63_V0.8410.68
88_N95_I0.8200.66
41_I60_A0.8130.65
8_L39_I0.8110.65
8_L84_C0.8090.65
51_K90_N0.8010.64
7_M42_T0.7910.63
41_I86_L0.7850.62
16_A52_V0.7830.62
22_I56_D0.7780.62
58_L95_I0.7740.61
52_V57_V0.7730.61
68_G78_R0.7640.60
27_G30_R0.7620.60
72_P109_S0.7550.59
14_S23_K0.7460.58
98_R118_L0.7350.57
32_Y96_G0.7330.57
111_K116_I0.7320.57
6_T51_K0.7310.57
106_E115_I0.7260.56
65_T69_V0.7220.56
51_K86_L0.7200.56
38_I92_E0.7160.55
61_V115_I0.7160.55
17_R47_I0.7130.55
14_S51_K0.7080.55
14_S47_I0.7070.54
41_I84_C0.7050.54
52_V56_D0.7030.54
87_L92_E0.7020.54
54_K102_P0.7020.54
46_A50_G0.6940.53
52_V72_P0.6890.53
12_D15_G0.6840.52
23_K28_S0.6790.51
58_L86_L0.6760.51
45_E54_K0.6750.51
55_G65_T0.6730.51
14_S96_G0.6700.51
100_F121_E0.6700.51
120_P123_L0.6670.50
104_T109_S0.6640.50
51_K109_S0.6610.50
10_V16_A0.6580.49
17_R22_I0.6570.49
25_L59_K0.6570.49
64_R102_P0.6530.49
81_G102_P0.6520.49
11_A94_P0.6430.48
118_L121_E0.6400.47
61_V112_F0.6390.47
116_I120_P0.6350.47
63_V83_A0.6350.47
88_N92_E0.6310.46
42_T57_V0.6230.46
103_V108_R0.6230.46
26_G105_R0.6220.45
55_G75_S0.6180.45
4_E66_K0.6170.45
64_R105_R0.6030.43
19_V58_L0.5980.43
34_G65_T0.5950.43
35_V65_T0.5930.42
69_V76_V0.5850.42
79_F102_P0.5830.41
59_K97_T0.5830.41
3_Q31_R0.5810.41
90_N95_I0.5800.41
30_R62_V0.5800.41
8_L21_C0.5770.41
16_A87_L0.5750.41
61_V104_T0.5750.41
89_N92_E0.5720.40
94_P118_L0.5710.40
44_K48_P0.5710.40
61_V100_F0.5590.39
11_A64_R0.5590.39
74_G77_I0.5580.39
21_C25_L0.5540.38
105_R121_E0.5520.38
59_K92_E0.5490.38
3_Q29_H0.5470.38
50_G75_S0.5440.37
4_E42_T0.5420.37
64_R71_R0.5420.37
62_V89_N0.5410.37
115_I118_L0.5410.37
29_H89_N0.5390.37
105_R112_F0.5390.37
10_V43_I0.5390.37
22_I29_H0.5300.36
79_F104_T0.5270.36
108_R122_V0.5260.36
96_G99_I0.5240.36
49_R56_D0.5240.36
107_L118_L0.5230.35
6_T21_C0.5220.35
66_K81_G0.5180.35
5_Q23_K0.5170.35
62_V120_P0.5170.35
117_S121_E0.5160.35
68_G77_I0.5130.34
41_I51_K0.5110.34
21_C84_C0.5060.34
23_K55_G0.5040.34
16_A46_A0.5020.33
21_C88_N0.5010.33
55_G95_I0.5010.33
55_G113_M0.5010.33
90_N114_K0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1whiA 2 0.9919 100 0.016 Contact Map
4rb6O 1 0.9919 100 0.016 Contact Map
4tp9K 1 0.9919 100 0.025 Contact Map
3bboM 1 0.9837 100 0.025 Contact Map
1vw4I 1 0.9756 100 0.04 Contact Map
3zf7W 1 0.9593 100 0.063 Contact Map
3j21J 1 0.9593 100 0.069 Contact Map
1vq8K 1 0.9593 100 0.072 Contact Map
4ujrI 1 0.9593 100 0.082 Contact Map
1vx7M 1 0.9593 100 0.083 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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