PPID - ECOLI - GREMLIN Contacts

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PPID - Peptidyl-prolyl cis-trans isomerase D

UniProt:	P0ADY1	Sequences: MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAKVNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLDQYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQLTTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYYEQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQTKTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVSDAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPGINSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLVDLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGNVVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13249
Length:	623 (596)
Sequences:	1943 (1564)
Seq/√Len:	64.1

ECOLI - PPID

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
213_E	494_K	4.896	1.00
252_I	364_L	4.441	1.00
215_A	219_E	4.308	1.00
214_I	479_L	4.140	1.00
288_E	293_G	3.910	1.00
253_Q	364_L	3.857	1.00
210_T	213_E	3.689	1.00
335_K	355_D	3.579	1.00
279_E	283_K	3.218	1.00
494_K	497_Q	3.176	1.00
286_L	290_N	3.142	1.00
248_S	251_D	3.112	1.00
334_E	337_Q	3.089	1.00
487_K	491_Q	3.024	1.00
225_F	489_L	3.013	1.00
321_A	328_K	3.009	1.00
294_D	297_A	3.008	1.00
272_S	354_D	2.945	1.00
253_Q	257_D	2.943	1.00
214_I	490_V	2.938	1.00
251_D	379_K	2.878	1.00
193_V	544_A	2.867	1.00
215_A	479_L	2.857	1.00
270_R	314_D	2.841	1.00
221_N	224_N	2.787	1.00
372_A	376_K	2.771	1.00
368_R	372_A	2.744	1.00
272_S	352_R	2.741	1.00
233_V	437_I	2.683	1.00
333_K	339_S	2.681	1.00
270_R	355_D	2.659	1.00
276_T	285_V	2.648	1.00
285_V	302_K	2.621	1.00
114_D	157_R	2.610	1.00
252_I	371_I	2.589	1.00
509_D	514_K	2.580	1.00
363_S	367_V	2.543	1.00
46_N	612_A	2.542	1.00
46_N	103_Q	2.506	1.00
219_E	222_K	2.502	1.00
318_L	323_I	2.499	1.00
283_K	287_D	2.483	1.00
268_R	357_Q	2.461	1.00
124_T	152_Y	2.382	1.00
194_R	573_D	2.308	1.00
483_Q	487_K	2.289	1.00
232_R	418_W	2.282	1.00
325_D	329_N	2.277	1.00
547_L	572_L	2.236	1.00
255_Y	259_H	2.207	1.00
286_L	350_I	2.196	1.00
211_E	483_Q	2.171	1.00
271_Y	318_L	2.151	1.00
234_S	469_S	2.150	1.00
203_L	499_A	2.140	1.00
232_R	417_G	2.125	1.00
138_Y	153_A	2.110	1.00
497_Q	501_V	2.094	1.00
289_L	298_L	2.039	1.00
194_R	571_A	2.032	1.00
198_I	499_A	1.962	1.00
270_R	354_D	1.955	1.00
217_Y	221_N	1.951	1.00
486_V	490_V	1.935	1.00
273_I	349_L	1.915	1.00
257_D	260_Q	1.908	1.00
297_A	300_K	1.869	1.00
286_L	341_V	1.845	1.00
176_L	179_E	1.825	1.00
216_S	220_Q	1.817	1.00
284_A	288_E	1.798	1.00
231_F	471_H	1.776	1.00
43_A	92_L	1.770	1.00
104_Y	107_E	1.754	1.00
365_D	368_R	1.745	1.00
282_A	350_I	1.740	0.99
255_Y	371_I	1.735	0.99
254_S	258_Q	1.717	0.99
92_L	96_I	1.714	0.99
232_R	470_E	1.709	0.99
207_Q	498_Q	1.699	0.99
190_Q	576_K	1.697	0.99
269_T	356_I	1.696	0.99
259_H	262_Q	1.692	0.99
212_Q	216_S	1.684	0.99
275_Q	346_V	1.682	0.99
270_R	317_W	1.678	0.99
214_I	483_Q	1.674	0.99
501_V	505_K	1.669	0.99
267_Q	356_I	1.668	0.99
97_D	609_R	1.664	0.99
192_V	574_E	1.655	0.99
62_E	65_R	1.650	0.99
344_S	347_G	1.648	0.99
222_K	476_V	1.647	0.99
486_V	489_L	1.641	0.99
2_M	6_R	1.636	0.99
203_L	502_D	1.636	0.99
230_Q	472_K	1.631	0.99
247_V	375_V	1.630	0.99
478_P	482_V	1.630	0.99
283_K	341_V	1.620	0.99
480_A	483_Q	1.616	0.99
544_A	570_L	1.610	0.99
250_A	254_S	1.609	0.99
125_P	128_Q	1.608	0.99
271_Y	331_G	1.604	0.99
493_N	497_Q	1.592	0.99
327_L	351_V	1.586	0.99
333_K	353_L	1.585	0.99
64_N	67_Q	1.584	0.99
181_D	185_A	1.582	0.99
383_A	386_A	1.580	0.99
289_L	338_L	1.569	0.99
278_T	281_E	1.568	0.99
371_I	375_V	1.568	0.99
129_V	134_D	1.564	0.99
58_A	95_L	1.561	0.99
500_K	504_E	1.547	0.99
249_D	368_R	1.543	0.99
218_Y	478_P	1.536	0.99
21_I	25_F	1.535	0.99
287_D	291_K	1.534	0.99
507_L	569_L	1.522	0.99
314_D	354_D	1.517	0.99
11_S	15_K	1.517	0.99
281_E	284_A	1.513	0.99
177_K	589_V	1.509	0.99
226_M	476_V	1.506	0.99
320_D	332_L	1.497	0.98
223_N	226_M	1.479	0.98
364_L	368_R	1.473	0.98
479_L	483_Q	1.470	0.98
44_K	49_E	1.470	0.98
93_N	609_R	1.469	0.98
55_F	59_F	1.468	0.98
504_E	508_V	1.466	0.98
363_S	366_E	1.464	0.98
297_A	301_E	1.464	0.98
252_I	372_A	1.453	0.98
226_M	474_E	1.451	0.98
227_T	477_K	1.446	0.98
317_W	355_D	1.441	0.98
288_E	302_K	1.440	0.98
403_A	407_Q	1.433	0.98
236_I	391_V	1.424	0.98
498_Q	501_V	1.424	0.98
342_I	351_V	1.420	0.98
288_E	301_E	1.418	0.98
502_D	505_K	1.416	0.98
237_K	462_R	1.412	0.98
89_Q	93_N	1.412	0.98
289_L	350_I	1.409	0.98
75_S	80_N	1.408	0.98
407_Q	410_G	1.405	0.98
384_Y	463_A	1.401	0.98
285_V	298_L	1.390	0.97
331_G	353_L	1.385	0.97
433_V	466_L	1.380	0.97
282_A	286_L	1.379	0.97
54_Q	99_A	1.377	0.97
418_W	472_K	1.368	0.97
214_I	486_V	1.366	0.97
406_E	413_A	1.355	0.97
275_Q	349_L	1.352	0.97
224_N	489_L	1.351	0.97
62_E	94_R	1.349	0.97
324_P	346_V	1.346	0.97
140_G	144_Q	1.345	0.97
281_E	304_A	1.342	0.97
252_I	375_V	1.339	0.97
279_E	348_F	1.334	0.97
249_D	253_Q	1.332	0.97
127_F	133_F	1.330	0.97
343_K	348_F	1.327	0.97
199_D	202_A	1.326	0.97
229_E	471_H	1.307	0.96
320_D	328_K	1.306	0.96
475_A	481_D	1.304	0.96
475_A	478_P	1.304	0.96
274_I	299_A	1.303	0.96
515_G	518_A	1.302	0.96
234_S	403_A	1.301	0.96
275_Q	347_G	1.300	0.96
100_L	608_L	1.295	0.96
117_V	156_L	1.286	0.96
48_Q	103_Q	1.279	0.96
129_V	137_R	1.277	0.96
477_K	485_Q	1.276	0.96
48_Q	99_A	1.274	0.96
135_N	139_N	1.273	0.96
263_F	370_D	1.272	0.96
453_S	466_L	1.265	0.96
501_V	504_E	1.257	0.95
287_D	290_N	1.254	0.95
251_D	254_S	1.254	0.95
286_L	338_L	1.251	0.95
239_D	242_T	1.249	0.95
508_V	512_A	1.245	0.95
191_R	575_V	1.238	0.95
606_S	609_R	1.237	0.95
393_D	397_N	1.233	0.95
2_M	5_L	1.231	0.95
477_K	482_V	1.230	0.95
141_I	145_M	1.229	0.95
142_L	145_M	1.228	0.95
139_N	143_N	1.227	0.95
204_A	495_A	1.225	0.95
323_I	346_V	1.225	0.95
159_Q	163_Q	1.225	0.95
24_S	28_T	1.223	0.95
136_S	139_N	1.223	0.95
344_S	349_L	1.218	0.95
117_V	153_A	1.211	0.94
5_L	9_A	1.211	0.94
507_L	511_K	1.209	0.94
55_F	91_V	1.208	0.94
290_N	340_G	1.201	0.94
362_K	366_E	1.200	0.94
217_Y	489_L	1.200	0.94
296_A	299_A	1.198	0.94
503_A	559_M	1.196	0.94
216_S	219_E	1.193	0.94
262_Q	374_K	1.189	0.94
212_Q	215_A	1.187	0.94
250_A	253_Q	1.187	0.94
234_S	467_R	1.184	0.94
369_D	373_A	1.183	0.94
2_M	11_S	1.179	0.94
298_L	302_K	1.173	0.93
275_Q	344_S	1.168	0.93
105_A	161_T	1.164	0.93
362_K	367_V	1.163	0.93
365_D	369_D	1.160	0.93
118_K	153_A	1.158	0.93
401_S	404_G	1.157	0.93
479_L	486_V	1.157	0.93
288_E	291_K	1.156	0.93
256_Y	363_S	1.156	0.93
65_R	69_Q	1.155	0.93
56_E	60_N	1.151	0.93
185_A	577_Q	1.149	0.93
15_K	18_F	1.145	0.93
391_V	409_A	1.141	0.92
267_Q	332_L	1.140	0.92
269_T	332_L	1.137	0.92
457_T	460_G	1.136	0.92
323_I	327_L	1.135	0.92
137_R	141_I	1.133	0.92
273_I	327_L	1.122	0.92
369_D	372_A	1.117	0.92
540_I	544_A	1.116	0.92
220_Q	493_N	1.114	0.92
192_V	576_K	1.110	0.91
327_L	349_L	1.107	0.91
209_V	490_V	1.100	0.91
198_I	506_L	1.100	0.91
390_K	394_A	1.091	0.91
490_V	494_K	1.088	0.91
234_S	415_Q	1.088	0.91
116_Q	164_Q	1.086	0.90
383_A	387_L	1.083	0.90
319_E	322_T	1.081	0.90
293_G	297_A	1.080	0.90
281_E	302_K	1.079	0.90
227_T	475_A	1.076	0.90
420_S	423_N	1.076	0.90
279_E	343_K	1.073	0.90
239_D	462_R	1.069	0.90
452_N	467_R	1.068	0.90
95_L	98_E	1.065	0.90
370_D	373_A	1.056	0.89
120_A	160_L	1.054	0.89
137_R	140_G	1.053	0.89
315_M	349_L	1.049	0.89
233_V	466_L	1.046	0.89
494_K	498_Q	1.043	0.89
253_Q	365_D	1.036	0.88
120_A	123_A	1.035	0.88
47_D	612_A	1.028	0.88
335_K	356_I	1.025	0.88
208_P	211_E	1.025	0.88
80_N	83_Y	1.024	0.88
118_K	122_F	1.024	0.88
213_E	490_V	1.024	0.88
177_K	181_D	1.022	0.88
277_K	304_A	1.020	0.87
271_Y	351_V	1.019	0.87
395_A	465_V	1.018	0.87
503_A	569_L	1.017	0.87
323_I	332_L	1.013	0.87
484_E	488_A	1.013	0.87
503_A	567_V	1.013	0.87
484_E	487_K	1.012	0.87
189_Q	577_Q	1.011	0.87
271_Y	353_L	1.010	0.87
324_P	327_L	1.007	0.87
318_L	331_G	1.003	0.87
181_D	585_K	1.003	0.87
271_Y	323_I	1.002	0.86
549_L	574_E	1.000	0.86
303_S	313_G	1.000	0.86
259_H	371_I	0.997	0.86
15_K	24_S	0.994	0.86
477_K	481_D	0.994	0.86
426_E	429_N	0.992	0.86
175_M	592_I	0.989	0.86
364_L	371_I	0.987	0.86
119_Q	123_A	0.986	0.86
510_L	513_G	0.982	0.85
9_A	15_K	0.982	0.85
317_W	357_Q	0.981	0.85
231_F	468_I	0.977	0.85
505_K	509_D	0.975	0.85
52_R	56_E	0.974	0.85
305_D	313_G	0.973	0.85
271_Y	275_Q	0.972	0.85
12_L	16_I	0.971	0.85
215_A	480_A	0.967	0.84
104_Y	108_L	0.966	0.84
440_G	448_A	0.966	0.84
289_L	292_G	0.965	0.84
391_V	405_A	0.963	0.84
272_S	314_D	0.961	0.84
189_Q	575_V	0.957	0.84
338_L	350_I	0.956	0.84
516_A	526_F	0.954	0.84
51_S	54_Q	0.954	0.84
433_V	464_F	0.952	0.84
247_V	372_A	0.951	0.83
233_V	416_T	0.949	0.83
19_G	23_V	0.949	0.83
336_G	354_D	0.948	0.83
286_L	340_G	0.948	0.83
21_I	24_S	0.947	0.83
149_A	153_A	0.947	0.83
218_Y	476_V	0.945	0.83
8_A	14_L	0.943	0.83
562_D	566_N	0.941	0.83
543_A	547_L	0.940	0.83
509_D	519_M	0.936	0.82
16_I	247_V	0.935	0.82
193_V	572_L	0.933	0.82
97_D	605_M	0.933	0.82
110_L	161_T	0.932	0.82
280_D	283_K	0.929	0.82
249_D	372_A	0.928	0.82
112_I	117_V	0.925	0.82
341_V	348_F	0.925	0.82
11_S	14_L	0.923	0.82
238_L	391_V	0.918	0.81
498_Q	502_D	0.915	0.81
332_L	356_I	0.915	0.81
333_K	337_Q	0.914	0.81
211_E	215_A	0.914	0.81
46_N	614_I	0.911	0.81
50_I	95_L	0.910	0.81
371_I	374_K	0.909	0.81
165_L	604_L	0.909	0.81
327_L	346_V	0.906	0.80
217_Y	224_N	0.906	0.80
150_D	153_A	0.902	0.80
273_I	351_V	0.901	0.80
583_D	586_K	0.900	0.80
41_Y	49_E	0.895	0.80
284_A	287_D	0.893	0.79
284_A	302_K	0.893	0.79
404_G	407_Q	0.891	0.79
544_A	572_L	0.891	0.79
391_V	465_V	0.888	0.79
320_D	329_N	0.885	0.79
255_Y	258_Q	0.885	0.79
586_K	590_Q	0.883	0.79
478_P	481_D	0.880	0.78
342_I	349_L	0.880	0.78
276_T	281_E	0.878	0.78
42_A	100_L	0.877	0.78
339_S	342_I	0.876	0.78
243_M	387_L	0.873	0.78
204_A	207_Q	0.872	0.78
259_H	263_F	0.870	0.78
229_E	473_P	0.864	0.77
120_A	156_L	0.862	0.77
485_Q	489_L	0.862	0.77
70_L	74_Y	0.861	0.77
102_D	162_T	0.858	0.77
276_T	282_A	0.857	0.77
124_T	128_Q	0.856	0.76
58_A	98_E	0.855	0.76
197_T	566_N	0.855	0.76
42_A	55_F	0.850	0.76
376_K	380_A	0.850	0.76
209_V	213_E	0.849	0.76
54_Q	57_N	0.848	0.76
510_L	516_A	0.845	0.76
12_L	15_K	0.845	0.76
134_D	137_R	0.845	0.76
502_D	506_L	0.842	0.75
3_D	11_S	0.841	0.75
180_T	585_K	0.839	0.75
225_F	486_V	0.839	0.75
368_R	483_Q	0.834	0.75
326_E	329_N	0.832	0.74
230_Q	418_W	0.830	0.74
237_K	414_T	0.829	0.74
495_A	499_A	0.828	0.74
324_P	332_L	0.827	0.74
299_A	313_G	0.822	0.74
99_A	103_Q	0.821	0.73
419_F	424_L	0.817	0.73
103_Q	612_A	0.817	0.73
117_V	122_F	0.817	0.73
547_L	570_L	0.814	0.73
295_F	313_G	0.813	0.73
449_P	470_E	0.812	0.73
280_D	284_A	0.812	0.73
198_I	502_D	0.811	0.73
263_F	362_K	0.811	0.73
99_A	102_D	0.809	0.72
402_L	452_N	0.806	0.72
180_T	589_V	0.806	0.72
295_F	316_G	0.806	0.72
46_N	100_L	0.805	0.72
225_F	485_Q	0.804	0.72
3_D	7_T	0.803	0.72
300_K	310_R	0.800	0.71
9_A	21_I	0.799	0.71
232_R	472_K	0.797	0.71
346_V	349_L	0.796	0.71
529_P	534_R	0.796	0.71
31_S	34_L	0.796	0.71
248_S	256_Y	0.796	0.71
398_D	404_G	0.796	0.71
321_A	327_L	0.796	0.71
559_M	567_V	0.796	0.71
295_F	350_I	0.793	0.71
14_L	22_I	0.790	0.71
148_T	151_Q	0.790	0.71
138_Y	149_A	0.790	0.71
299_A	312_G	0.789	0.70
232_R	469_S	0.789	0.70
110_L	164_Q	0.789	0.70
375_V	379_K	0.788	0.70
214_I	487_K	0.788	0.70
28_T	31_S	0.788	0.70
19_G	24_S	0.787	0.70
18_F	22_I	0.784	0.70
26_I	30_V	0.783	0.70
58_A	61_S	0.783	0.70
366_E	369_D	0.781	0.70
403_A	406_E	0.781	0.70
273_I	346_V	0.776	0.69
455_I	465_V	0.776	0.69
274_I	305_D	0.775	0.69
213_E	216_S	0.774	0.69
217_Y	486_V	0.774	0.69
102_D	158_N	0.772	0.69
479_L	482_V	0.770	0.69
337_Q	340_G	0.768	0.68
164_Q	189_Q	0.768	0.68
41_Y	44_K	0.768	0.68
203_L	498_Q	0.767	0.68
130_D	134_D	0.767	0.68
218_Y	486_V	0.766	0.68
562_D	568_V	0.766	0.68
394_A	408_A	0.764	0.68
8_A	17_I	0.761	0.68
560_A	569_L	0.761	0.68
161_T	165_L	0.757	0.67
62_E	91_V	0.757	0.67
260_Q	264_T	0.756	0.67
110_L	134_D	0.754	0.67
60_N	64_N	0.754	0.67
368_R	376_K	0.754	0.67
287_D	497_Q	0.753	0.67
29_G	32_G	0.752	0.67
230_Q	416_T	0.752	0.67
509_D	513_G	0.751	0.67
370_D	374_K	0.750	0.67
510_L	514_K	0.750	0.67
362_K	370_D	0.750	0.67
185_A	189_Q	0.747	0.66
71_G	74_Y	0.746	0.66
290_N	350_I	0.746	0.66
324_P	345_S	0.745	0.66
141_I	149_A	0.743	0.66
543_A	570_L	0.740	0.65
324_P	344_S	0.740	0.65
20_I	24_S	0.739	0.65
366_E	370_D	0.739	0.65
264_T	359_A	0.737	0.65
305_D	312_G	0.736	0.65
121_I	169_V	0.736	0.65
142_L	147_M	0.736	0.65
27_L	30_V	0.735	0.65
334_E	520_Q	0.731	0.65
136_S	140_G	0.730	0.64
104_Y	604_L	0.729	0.64
2_M	14_L	0.729	0.64
416_T	419_F	0.728	0.64
285_V	288_E	0.726	0.64
315_M	318_L	0.726	0.64
90_Q	94_R	0.725	0.64
20_I	25_F	0.723	0.64
259_H	374_K	0.722	0.64
593_T	597_A	0.722	0.64
247_V	380_A	0.721	0.63
232_R	415_Q	0.719	0.63
263_F	367_V	0.719	0.63
283_K	340_G	0.719	0.63
263_F	371_I	0.719	0.63
290_N	338_L	0.718	0.63
46_N	99_A	0.717	0.63
275_Q	305_D	0.716	0.63
379_K	390_K	0.714	0.63
211_E	487_K	0.713	0.63
509_D	512_A	0.712	0.62
334_E	353_L	0.711	0.62
103_Q	106_R	0.711	0.62
100_L	614_I	0.711	0.62
453_S	465_V	0.709	0.62
305_D	315_M	0.707	0.62
506_L	590_Q	0.705	0.62
606_S	610_K	0.704	0.62
273_I	315_M	0.701	0.61
324_P	328_K	0.700	0.61
124_T	145_M	0.700	0.61
387_L	390_K	0.699	0.61
500_K	567_V	0.698	0.61
305_D	349_L	0.698	0.61
418_W	423_N	0.698	0.61
293_G	298_L	0.697	0.61
147_M	155_A	0.697	0.61
437_I	466_L	0.695	0.61
521_A	524_L	0.693	0.60
26_I	395_A	0.693	0.60
227_T	230_Q	0.693	0.60
393_D	396_S	0.693	0.60
528_E	534_R	0.692	0.60
16_I	22_I	0.692	0.60
11_S	24_S	0.690	0.60
274_I	313_G	0.689	0.60
535_S	538_D	0.689	0.60
305_D	342_I	0.688	0.60
504_E	559_M	0.687	0.60
607_N	611_E	0.687	0.60
267_Q	358_P	0.687	0.60
18_F	225_F	0.687	0.60
269_T	331_G	0.686	0.60
458_V	462_R	0.686	0.60
424_L	434_A	0.683	0.59
341_V	350_I	0.683	0.59
275_Q	327_L	0.682	0.59
278_T	304_A	0.682	0.59
309_A	312_G	0.679	0.59
273_I	305_D	0.679	0.59
140_G	143_N	0.678	0.59
250_A	410_G	0.678	0.59
273_I	303_S	0.678	0.59
364_L	375_V	0.676	0.59
204_A	491_Q	0.676	0.59
127_F	131_G	0.675	0.58
235_Y	466_L	0.673	0.58
364_L	367_V	0.672	0.58
4_S	7_T	0.672	0.58
91_V	127_F	0.672	0.58
296_A	312_G	0.671	0.58
505_K	508_V	0.671	0.58
154_Q	157_R	0.670	0.58
544_A	547_L	0.670	0.58
314_D	317_W	0.670	0.58
16_I	19_G	0.669	0.58
287_D	301_E	0.667	0.57
209_V	487_K	0.666	0.57
323_I	331_G	0.661	0.57
200_V	495_A	0.661	0.57
459_D	462_R	0.660	0.57
18_F	24_S	0.658	0.56
191_R	545_F	0.658	0.56
96_I	614_I	0.657	0.56
289_L	550_P	0.657	0.56
252_I	368_R	0.657	0.56
492_H	496_E	0.656	0.56
218_Y	475_A	0.655	0.56
212_Q	480_A	0.653	0.56
23_V	27_L	0.652	0.56
50_I	75_S	0.652	0.56
333_K	340_G	0.652	0.56
218_Y	222_K	0.651	0.56
315_M	327_L	0.649	0.55
17_I	28_T	0.649	0.55
75_S	81_E	0.648	0.55
328_K	332_L	0.647	0.55
203_L	495_A	0.646	0.55
203_L	206_K	0.646	0.55
526_F	529_P	0.645	0.55
365_D	484_E	0.644	0.55
206_K	498_Q	0.643	0.55
267_Q	320_D	0.643	0.55
508_V	511_K	0.643	0.55
299_A	309_A	0.642	0.55
318_L	329_N	0.642	0.55
2_M	18_F	0.642	0.55
149_A	152_Y	0.642	0.55
14_L	18_F	0.642	0.55
563_M	566_N	0.640	0.54
248_S	252_I	0.640	0.54
303_S	312_G	0.638	0.54
458_V	464_F	0.638	0.54
191_R	269_T	0.637	0.54
231_F	437_I	0.637	0.54
112_I	161_T	0.637	0.54
155_A	159_Q	0.634	0.54
6_R	11_S	0.634	0.54
231_F	421_K	0.633	0.54
419_F	423_N	0.632	0.53
363_S	369_D	0.632	0.53
271_Y	327_L	0.632	0.53
540_I	570_L	0.631	0.53
360_K	366_E	0.631	0.53
274_I	312_G	0.630	0.53
391_V	402_L	0.629	0.53
315_M	331_G	0.628	0.53
193_V	540_I	0.627	0.53
268_R	317_W	0.625	0.53
314_D	355_D	0.625	0.53
24_S	27_L	0.624	0.53
217_Y	225_F	0.624	0.53
112_I	258_Q	0.624	0.53
156_L	159_Q	0.623	0.52
368_R	371_I	0.621	0.52
421_K	438_F	0.621	0.52
587_A	591_G	0.620	0.52
232_R	416_T	0.620	0.52
506_L	569_L	0.619	0.52
272_S	313_G	0.619	0.52
303_S	349_L	0.618	0.52
326_E	343_K	0.618	0.52
419_F	437_I	0.617	0.52
152_Y	156_L	0.616	0.52
602_E	606_S	0.616	0.52
405_A	408_A	0.616	0.52
255_Y	262_Q	0.615	0.52
273_I	313_G	0.615	0.52
274_I	303_S	0.615	0.52
133_F	142_L	0.614	0.51
253_Q	260_Q	0.614	0.51
523_G	528_E	0.614	0.51
510_L	557_Y	0.613	0.51
241_A	244_Q	0.611	0.51
598_Q	602_E	0.611	0.51
514_K	518_A	0.610	0.51
364_L	372_A	0.610	0.51
274_I	295_F	0.609	0.51
171_G	175_M	0.609	0.51
392_S	465_V	0.609	0.51
323_I	328_K	0.607	0.51
53_G	56_E	0.605	0.50
437_I	458_V	0.604	0.50
46_N	613_K	0.604	0.50
366_E	371_I	0.604	0.50
594_Q	598_Q	0.602	0.50
184_A	188_A	0.602	0.50
248_S	379_K	0.601	0.50
510_L	515_G	0.601	0.50
419_F	422_D	0.601	0.50
415_Q	469_S	0.600	0.50
271_Y	332_L	0.599	0.50
121_I	133_F	0.597	0.49
18_F	25_F	0.597	0.49
548_P	556_S	0.596	0.49
279_E	341_V	0.595	0.49
55_F	92_L	0.594	0.49
394_A	409_A	0.594	0.49
8_A	24_S	0.592	0.49
205_A	495_A	0.592	0.49
547_L	558_G	0.591	0.49
256_Y	362_K	0.590	0.49
112_I	519_M	0.590	0.49
248_S	262_Q	0.590	0.49
329_N	337_Q	0.589	0.48
294_D	352_R	0.588	0.48
335_K	353_L	0.588	0.48
516_A	519_M	0.588	0.48
248_S	253_Q	0.587	0.48
209_V	491_Q	0.585	0.48
108_L	236_I	0.585	0.48
211_E	245_Q	0.584	0.48
45_V	69_Q	0.583	0.48
20_I	105_A	0.582	0.48
18_F	21_I	0.582	0.48
248_S	255_Y	0.582	0.48
585_K	589_V	0.581	0.48
168_G	176_L	0.580	0.47
121_I	138_Y	0.580	0.47
299_A	303_S	0.579	0.47
273_I	342_I	0.578	0.47
43_A	96_I	0.577	0.47
209_V	214_I	0.577	0.47
98_E	162_T	0.577	0.47
3_D	209_V	0.576	0.47
21_I	26_I	0.576	0.47
288_E	298_L	0.576	0.47
198_I	203_L	0.575	0.47
472_K	475_A	0.575	0.47
5_L	8_A	0.574	0.47
196_A	516_A	0.573	0.47
8_A	15_K	0.572	0.47
91_V	95_L	0.572	0.47
218_Y	341_V	0.572	0.47
457_T	463_A	0.572	0.47
275_Q	324_P	0.570	0.46
249_D	364_L	0.569	0.46
199_D	566_N	0.569	0.46
431_K	435_D	0.568	0.46
432_P	435_D	0.568	0.46
225_F	397_N	0.568	0.46
269_T	353_L	0.567	0.46
223_N	580_M	0.567	0.46
273_I	312_G	0.566	0.46
210_T	487_K	0.566	0.46
179_E	596_N	0.566	0.46
384_Y	388_Q	0.566	0.46
331_G	351_V	0.564	0.46
145_M	389_Q	0.564	0.46
397_N	452_N	0.563	0.45
312_G	349_L	0.563	0.45
272_S	299_A	0.563	0.45
87_L	90_Q	0.562	0.45
45_V	103_Q	0.561	0.45
348_F	499_A	0.561	0.45
250_A	279_E	0.561	0.45
298_L	303_S	0.561	0.45
100_L	605_M	0.560	0.45
377_H	380_A	0.559	0.45
113_S	483_Q	0.559	0.45
389_Q	393_D	0.559	0.45
427_E	434_A	0.558	0.45
119_Q	122_F	0.557	0.45
181_D	580_M	0.557	0.45
36_G	570_L	0.557	0.45
14_L	24_S	0.556	0.45
7_T	11_S	0.556	0.45
15_K	22_I	0.555	0.45
247_V	501_V	0.555	0.45
100_L	612_A	0.554	0.44
283_K	286_L	0.554	0.44
233_V	419_F	0.553	0.44
298_L	323_I	0.553	0.44
274_I	285_V	0.551	0.44
185_A	578_G	0.550	0.44
470_E	518_A	0.550	0.44
372_A	375_V	0.550	0.44
405_A	409_A	0.549	0.44
539_P	542_Q	0.549	0.44
94_R	98_E	0.548	0.44
289_L	499_A	0.548	0.44
208_P	514_K	0.548	0.44
595_N	599_I	0.547	0.44
248_S	254_S	0.546	0.44
528_E	531_T	0.545	0.43
324_P	329_N	0.545	0.43
435_D	439_N	0.544	0.43
532_L	536_G	0.544	0.43
121_I	576_K	0.544	0.43
418_W	470_E	0.544	0.43
523_G	534_R	0.544	0.43
161_T	221_N	0.544	0.43
381_L	437_I	0.543	0.43
121_I	153_A	0.542	0.43
50_I	478_P	0.541	0.43
183_L	187_V	0.540	0.43
221_N	486_V	0.540	0.43
315_M	346_V	0.539	0.43
14_L	23_V	0.539	0.43
278_T	321_A	0.538	0.43
331_G	339_S	0.538	0.43
254_S	257_D	0.538	0.43
225_F	482_V	0.538	0.43
392_S	395_A	0.537	0.43
213_E	402_L	0.537	0.43
164_Q	168_G	0.537	0.43
244_Q	376_K	0.536	0.42
13_V	16_I	0.536	0.42
167_N	595_N	0.536	0.42
319_E	328_K	0.536	0.42
427_E	433_V	0.536	0.42
394_A	405_A	0.536	0.42
428_L	434_A	0.536	0.42
483_Q	486_V	0.536	0.42
167_N	225_F	0.535	0.42
19_G	22_I	0.534	0.42
42_A	51_S	0.534	0.42
328_K	331_G	0.533	0.42
480_A	484_E	0.531	0.42
506_L	519_M	0.531	0.42
197_T	568_V	0.531	0.42
16_I	96_I	0.531	0.42
396_S	503_A	0.530	0.42
497_Q	500_K	0.530	0.42
298_L	301_E	0.529	0.42
107_E	211_E	0.529	0.42
127_F	137_R	0.529	0.42
146_G	156_L	0.528	0.41
123_A	160_L	0.528	0.41
516_A	571_A	0.528	0.41
268_R	319_E	0.527	0.41
586_K	589_V	0.526	0.41
499_A	567_V	0.526	0.41
157_R	161_T	0.526	0.41
30_V	44_K	0.526	0.41
193_V	524_L	0.525	0.41
51_S	481_D	0.525	0.41
5_L	14_L	0.525	0.41
557_Y	571_A	0.524	0.41
43_A	55_F	0.524	0.41
294_D	298_L	0.524	0.41
276_T	304_A	0.524	0.41
281_E	328_K	0.524	0.41
26_I	31_S	0.523	0.41
526_F	534_R	0.522	0.41
35_I	110_L	0.521	0.41
362_K	408_A	0.521	0.41
86_T	209_V	0.521	0.41
585_K	588_M	0.521	0.41
9_A	14_L	0.520	0.41
299_A	305_D	0.520	0.41
263_F	369_D	0.520	0.41
225_F	457_T	0.520	0.41
275_Q	278_T	0.520	0.41
333_K	338_L	0.520	0.41
271_Y	349_L	0.520	0.41
147_M	151_Q	0.519	0.40
48_Q	109_K	0.519	0.40
131_G	134_D	0.518	0.40
278_T	524_L	0.518	0.40
275_Q	313_G	0.518	0.40
590_Q	594_Q	0.517	0.40
54_Q	615_K	0.517	0.40
158_N	413_A	0.517	0.40
35_I	171_G	0.516	0.40
111_G	161_T	0.516	0.40
391_V	395_A	0.516	0.40
289_L	387_L	0.515	0.40
212_Q	368_R	0.514	0.40
509_D	537_R	0.514	0.40
523_G	529_P	0.514	0.40
69_Q	93_N	0.513	0.40
285_V	293_G	0.513	0.40
306_I	346_V	0.513	0.40
112_I	160_L	0.513	0.40
24_S	29_G	0.512	0.40
105_A	165_L	0.512	0.40
17_I	293_G	0.512	0.40
304_A	309_A	0.512	0.40
260_Q	484_E	0.512	0.40
47_D	313_G	0.511	0.40
365_D	512_A	0.511	0.40
62_E	66_M	0.511	0.40
208_P	491_Q	0.510	0.39
251_D	375_V	0.510	0.39
158_N	350_I	0.510	0.39
191_R	513_G	0.509	0.39
547_L	551_A	0.509	0.39
275_Q	323_I	0.509	0.39
299_A	314_D	0.509	0.39
16_I	598_Q	0.508	0.39
306_I	309_A	0.508	0.39
192_V	531_T	0.508	0.39
212_Q	353_L	0.508	0.39
80_N	236_I	0.507	0.39
306_I	323_I	0.507	0.39
115_E	118_K	0.507	0.39
62_E	401_S	0.507	0.39
67_Q	71_G	0.507	0.39
256_Y	361_V	0.506	0.39
198_I	503_A	0.505	0.39
231_F	438_F	0.505	0.39
26_I	497_Q	0.505	0.39
396_S	452_N	0.505	0.39
17_I	395_A	0.503	0.39
424_L	427_E	0.503	0.39
60_N	129_V	0.503	0.39
309_A	354_D	0.503	0.39
48_Q	583_D	0.502	0.39
333_K	608_L	0.502	0.39
325_D	328_K	0.502	0.39
376_K	379_K	0.502	0.39
121_I	459_D	0.502	0.39
56_E	91_V	0.502	0.39
216_S	221_N	0.501	0.38
175_M	593_T	0.500	0.38
337_Q	353_L	0.500	0.38
263_F	266_P	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1m5yA	1	0.6051	100	0.611	Contact Map
3nrkA	3	0.4655	100	0.675	Contact Map
3rgcA	2	0.4013	100	0.721	Contact Map
4wo7A	2	0.4029	100	0.726	Contact Map
3rfwA	2	0.3917	100	0.728	Contact Map
3tc5A	1	0.1942	100	0.813	Contact Map
1yw5A	1	0.2681	100	0.82	Contact Map
2kgjA	1	0.1621	99.9	0.83	Contact Map
3i6cA	1	0.1445	99.9	0.833	Contact Map
2m08A	1	0.1477	99.9	0.835	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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