GREMLIN Database
PPID - Peptidyl-prolyl cis-trans isomerase D
UniProt: P0ADY1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13249
Length: 623 (596)
Sequences: 1943 (1564)
Seq/√Len: 64.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
213_E494_K4.8961.00
252_I364_L4.4411.00
215_A219_E4.3081.00
214_I479_L4.1401.00
288_E293_G3.9101.00
253_Q364_L3.8571.00
210_T213_E3.6891.00
335_K355_D3.5791.00
279_E283_K3.2181.00
494_K497_Q3.1761.00
286_L290_N3.1421.00
248_S251_D3.1121.00
334_E337_Q3.0891.00
487_K491_Q3.0241.00
225_F489_L3.0131.00
321_A328_K3.0091.00
294_D297_A3.0081.00
272_S354_D2.9451.00
253_Q257_D2.9431.00
214_I490_V2.9381.00
251_D379_K2.8781.00
193_V544_A2.8671.00
215_A479_L2.8571.00
270_R314_D2.8411.00
221_N224_N2.7871.00
372_A376_K2.7711.00
368_R372_A2.7441.00
272_S352_R2.7411.00
233_V437_I2.6831.00
333_K339_S2.6811.00
270_R355_D2.6591.00
276_T285_V2.6481.00
285_V302_K2.6211.00
114_D157_R2.6101.00
252_I371_I2.5891.00
509_D514_K2.5801.00
363_S367_V2.5431.00
46_N612_A2.5421.00
46_N103_Q2.5061.00
219_E222_K2.5021.00
318_L323_I2.4991.00
283_K287_D2.4831.00
268_R357_Q2.4611.00
124_T152_Y2.3821.00
194_R573_D2.3081.00
483_Q487_K2.2891.00
232_R418_W2.2821.00
325_D329_N2.2771.00
547_L572_L2.2361.00
255_Y259_H2.2071.00
286_L350_I2.1961.00
211_E483_Q2.1711.00
271_Y318_L2.1511.00
234_S469_S2.1501.00
203_L499_A2.1401.00
232_R417_G2.1251.00
138_Y153_A2.1101.00
497_Q501_V2.0941.00
289_L298_L2.0391.00
194_R571_A2.0321.00
198_I499_A1.9621.00
270_R354_D1.9551.00
217_Y221_N1.9511.00
486_V490_V1.9351.00
273_I349_L1.9151.00
257_D260_Q1.9081.00
297_A300_K1.8691.00
286_L341_V1.8451.00
176_L179_E1.8251.00
216_S220_Q1.8171.00
284_A288_E1.7981.00
231_F471_H1.7761.00
43_A92_L1.7701.00
104_Y107_E1.7541.00
365_D368_R1.7451.00
282_A350_I1.7400.99
255_Y371_I1.7350.99
254_S258_Q1.7170.99
92_L96_I1.7140.99
232_R470_E1.7090.99
207_Q498_Q1.6990.99
190_Q576_K1.6970.99
269_T356_I1.6960.99
259_H262_Q1.6920.99
212_Q216_S1.6840.99
275_Q346_V1.6820.99
270_R317_W1.6780.99
214_I483_Q1.6740.99
501_V505_K1.6690.99
267_Q356_I1.6680.99
97_D609_R1.6640.99
192_V574_E1.6550.99
62_E65_R1.6500.99
344_S347_G1.6480.99
222_K476_V1.6470.99
486_V489_L1.6410.99
2_M6_R1.6360.99
203_L502_D1.6360.99
230_Q472_K1.6310.99
247_V375_V1.6300.99
478_P482_V1.6300.99
283_K341_V1.6200.99
480_A483_Q1.6160.99
544_A570_L1.6100.99
250_A254_S1.6090.99
125_P128_Q1.6080.99
271_Y331_G1.6040.99
493_N497_Q1.5920.99
327_L351_V1.5860.99
333_K353_L1.5850.99
64_N67_Q1.5840.99
181_D185_A1.5820.99
383_A386_A1.5800.99
289_L338_L1.5690.99
278_T281_E1.5680.99
371_I375_V1.5680.99
129_V134_D1.5640.99
58_A95_L1.5610.99
500_K504_E1.5470.99
249_D368_R1.5430.99
218_Y478_P1.5360.99
21_I25_F1.5350.99
287_D291_K1.5340.99
507_L569_L1.5220.99
314_D354_D1.5170.99
11_S15_K1.5170.99
281_E284_A1.5130.99
177_K589_V1.5090.99
226_M476_V1.5060.99
320_D332_L1.4970.98
223_N226_M1.4790.98
364_L368_R1.4730.98
479_L483_Q1.4700.98
44_K49_E1.4700.98
93_N609_R1.4690.98
55_F59_F1.4680.98
504_E508_V1.4660.98
363_S366_E1.4640.98
297_A301_E1.4640.98
252_I372_A1.4530.98
226_M474_E1.4510.98
227_T477_K1.4460.98
317_W355_D1.4410.98
288_E302_K1.4400.98
403_A407_Q1.4330.98
236_I391_V1.4240.98
498_Q501_V1.4240.98
342_I351_V1.4200.98
288_E301_E1.4180.98
502_D505_K1.4160.98
237_K462_R1.4120.98
89_Q93_N1.4120.98
289_L350_I1.4090.98
75_S80_N1.4080.98
407_Q410_G1.4050.98
384_Y463_A1.4010.98
285_V298_L1.3900.97
331_G353_L1.3850.97
433_V466_L1.3800.97
282_A286_L1.3790.97
54_Q99_A1.3770.97
418_W472_K1.3680.97
214_I486_V1.3660.97
406_E413_A1.3550.97
275_Q349_L1.3520.97
224_N489_L1.3510.97
62_E94_R1.3490.97
324_P346_V1.3460.97
140_G144_Q1.3450.97
281_E304_A1.3420.97
252_I375_V1.3390.97
279_E348_F1.3340.97
249_D253_Q1.3320.97
127_F133_F1.3300.97
343_K348_F1.3270.97
199_D202_A1.3260.97
229_E471_H1.3070.96
320_D328_K1.3060.96
475_A481_D1.3040.96
475_A478_P1.3040.96
274_I299_A1.3030.96
515_G518_A1.3020.96
234_S403_A1.3010.96
275_Q347_G1.3000.96
100_L608_L1.2950.96
117_V156_L1.2860.96
48_Q103_Q1.2790.96
129_V137_R1.2770.96
477_K485_Q1.2760.96
48_Q99_A1.2740.96
135_N139_N1.2730.96
263_F370_D1.2720.96
453_S466_L1.2650.96
501_V504_E1.2570.95
287_D290_N1.2540.95
251_D254_S1.2540.95
286_L338_L1.2510.95
239_D242_T1.2490.95
508_V512_A1.2450.95
191_R575_V1.2380.95
606_S609_R1.2370.95
393_D397_N1.2330.95
2_M5_L1.2310.95
477_K482_V1.2300.95
141_I145_M1.2290.95
142_L145_M1.2280.95
139_N143_N1.2270.95
204_A495_A1.2250.95
323_I346_V1.2250.95
159_Q163_Q1.2250.95
24_S28_T1.2230.95
136_S139_N1.2230.95
344_S349_L1.2180.95
117_V153_A1.2110.94
5_L9_A1.2110.94
507_L511_K1.2090.94
55_F91_V1.2080.94
290_N340_G1.2010.94
362_K366_E1.2000.94
217_Y489_L1.2000.94
296_A299_A1.1980.94
503_A559_M1.1960.94
216_S219_E1.1930.94
262_Q374_K1.1890.94
212_Q215_A1.1870.94
250_A253_Q1.1870.94
234_S467_R1.1840.94
369_D373_A1.1830.94
2_M11_S1.1790.94
298_L302_K1.1730.93
275_Q344_S1.1680.93
105_A161_T1.1640.93
362_K367_V1.1630.93
365_D369_D1.1600.93
118_K153_A1.1580.93
401_S404_G1.1570.93
479_L486_V1.1570.93
288_E291_K1.1560.93
256_Y363_S1.1560.93
65_R69_Q1.1550.93
56_E60_N1.1510.93
185_A577_Q1.1490.93
15_K18_F1.1450.93
391_V409_A1.1410.92
267_Q332_L1.1400.92
269_T332_L1.1370.92
457_T460_G1.1360.92
323_I327_L1.1350.92
137_R141_I1.1330.92
273_I327_L1.1220.92
369_D372_A1.1170.92
540_I544_A1.1160.92
220_Q493_N1.1140.92
192_V576_K1.1100.91
327_L349_L1.1070.91
209_V490_V1.1000.91
198_I506_L1.1000.91
390_K394_A1.0910.91
490_V494_K1.0880.91
234_S415_Q1.0880.91
116_Q164_Q1.0860.90
383_A387_L1.0830.90
319_E322_T1.0810.90
293_G297_A1.0800.90
281_E302_K1.0790.90
227_T475_A1.0760.90
420_S423_N1.0760.90
279_E343_K1.0730.90
239_D462_R1.0690.90
452_N467_R1.0680.90
95_L98_E1.0650.90
370_D373_A1.0560.89
120_A160_L1.0540.89
137_R140_G1.0530.89
315_M349_L1.0490.89
233_V466_L1.0460.89
494_K498_Q1.0430.89
253_Q365_D1.0360.88
120_A123_A1.0350.88
47_D612_A1.0280.88
335_K356_I1.0250.88
208_P211_E1.0250.88
80_N83_Y1.0240.88
118_K122_F1.0240.88
213_E490_V1.0240.88
177_K181_D1.0220.88
277_K304_A1.0200.87
271_Y351_V1.0190.87
395_A465_V1.0180.87
503_A569_L1.0170.87
323_I332_L1.0130.87
484_E488_A1.0130.87
503_A567_V1.0130.87
484_E487_K1.0120.87
189_Q577_Q1.0110.87
271_Y353_L1.0100.87
324_P327_L1.0070.87
318_L331_G1.0030.87
181_D585_K1.0030.87
271_Y323_I1.0020.86
549_L574_E1.0000.86
303_S313_G1.0000.86
259_H371_I0.9970.86
15_K24_S0.9940.86
477_K481_D0.9940.86
426_E429_N0.9920.86
175_M592_I0.9890.86
364_L371_I0.9870.86
119_Q123_A0.9860.86
510_L513_G0.9820.85
9_A15_K0.9820.85
317_W357_Q0.9810.85
231_F468_I0.9770.85
505_K509_D0.9750.85
52_R56_E0.9740.85
305_D313_G0.9730.85
271_Y275_Q0.9720.85
12_L16_I0.9710.85
215_A480_A0.9670.84
104_Y108_L0.9660.84
440_G448_A0.9660.84
289_L292_G0.9650.84
391_V405_A0.9630.84
272_S314_D0.9610.84
189_Q575_V0.9570.84
338_L350_I0.9560.84
516_A526_F0.9540.84
51_S54_Q0.9540.84
433_V464_F0.9520.84
247_V372_A0.9510.83
233_V416_T0.9490.83
19_G23_V0.9490.83
336_G354_D0.9480.83
286_L340_G0.9480.83
21_I24_S0.9470.83
149_A153_A0.9470.83
218_Y476_V0.9450.83
8_A14_L0.9430.83
562_D566_N0.9410.83
543_A547_L0.9400.83
509_D519_M0.9360.82
16_I247_V0.9350.82
193_V572_L0.9330.82
97_D605_M0.9330.82
110_L161_T0.9320.82
280_D283_K0.9290.82
249_D372_A0.9280.82
112_I117_V0.9250.82
341_V348_F0.9250.82
11_S14_L0.9230.82
238_L391_V0.9180.81
498_Q502_D0.9150.81
332_L356_I0.9150.81
333_K337_Q0.9140.81
211_E215_A0.9140.81
46_N614_I0.9110.81
50_I95_L0.9100.81
371_I374_K0.9090.81
165_L604_L0.9090.81
327_L346_V0.9060.80
217_Y224_N0.9060.80
150_D153_A0.9020.80
273_I351_V0.9010.80
583_D586_K0.9000.80
41_Y49_E0.8950.80
284_A287_D0.8930.79
284_A302_K0.8930.79
404_G407_Q0.8910.79
544_A572_L0.8910.79
391_V465_V0.8880.79
320_D329_N0.8850.79
255_Y258_Q0.8850.79
586_K590_Q0.8830.79
478_P481_D0.8800.78
342_I349_L0.8800.78
276_T281_E0.8780.78
42_A100_L0.8770.78
339_S342_I0.8760.78
243_M387_L0.8730.78
204_A207_Q0.8720.78
259_H263_F0.8700.78
229_E473_P0.8640.77
120_A156_L0.8620.77
485_Q489_L0.8620.77
70_L74_Y0.8610.77
102_D162_T0.8580.77
276_T282_A0.8570.77
124_T128_Q0.8560.76
58_A98_E0.8550.76
197_T566_N0.8550.76
42_A55_F0.8500.76
376_K380_A0.8500.76
209_V213_E0.8490.76
54_Q57_N0.8480.76
510_L516_A0.8450.76
12_L15_K0.8450.76
134_D137_R0.8450.76
502_D506_L0.8420.75
3_D11_S0.8410.75
180_T585_K0.8390.75
225_F486_V0.8390.75
368_R483_Q0.8340.75
326_E329_N0.8320.74
230_Q418_W0.8300.74
237_K414_T0.8290.74
495_A499_A0.8280.74
324_P332_L0.8270.74
299_A313_G0.8220.74
99_A103_Q0.8210.73
419_F424_L0.8170.73
103_Q612_A0.8170.73
117_V122_F0.8170.73
547_L570_L0.8140.73
295_F313_G0.8130.73
449_P470_E0.8120.73
280_D284_A0.8120.73
198_I502_D0.8110.73
263_F362_K0.8110.73
99_A102_D0.8090.72
402_L452_N0.8060.72
180_T589_V0.8060.72
295_F316_G0.8060.72
46_N100_L0.8050.72
225_F485_Q0.8040.72
3_D7_T0.8030.72
300_K310_R0.8000.71
9_A21_I0.7990.71
232_R472_K0.7970.71
346_V349_L0.7960.71
529_P534_R0.7960.71
31_S34_L0.7960.71
248_S256_Y0.7960.71
398_D404_G0.7960.71
321_A327_L0.7960.71
559_M567_V0.7960.71
295_F350_I0.7930.71
14_L22_I0.7900.71
148_T151_Q0.7900.71
138_Y149_A0.7900.71
299_A312_G0.7890.70
232_R469_S0.7890.70
110_L164_Q0.7890.70
375_V379_K0.7880.70
214_I487_K0.7880.70
28_T31_S0.7880.70
19_G24_S0.7870.70
18_F22_I0.7840.70
26_I30_V0.7830.70
58_A61_S0.7830.70
366_E369_D0.7810.70
403_A406_E0.7810.70
273_I346_V0.7760.69
455_I465_V0.7760.69
274_I305_D0.7750.69
213_E216_S0.7740.69
217_Y486_V0.7740.69
102_D158_N0.7720.69
479_L482_V0.7700.69
337_Q340_G0.7680.68
164_Q189_Q0.7680.68
41_Y44_K0.7680.68
203_L498_Q0.7670.68
130_D134_D0.7670.68
218_Y486_V0.7660.68
562_D568_V0.7660.68
394_A408_A0.7640.68
8_A17_I0.7610.68
560_A569_L0.7610.68
161_T165_L0.7570.67
62_E91_V0.7570.67
260_Q264_T0.7560.67
110_L134_D0.7540.67
60_N64_N0.7540.67
368_R376_K0.7540.67
287_D497_Q0.7530.67
29_G32_G0.7520.67
230_Q416_T0.7520.67
509_D513_G0.7510.67
370_D374_K0.7500.67
510_L514_K0.7500.67
362_K370_D0.7500.67
185_A189_Q0.7470.66
71_G74_Y0.7460.66
290_N350_I0.7460.66
324_P345_S0.7450.66
141_I149_A0.7430.66
543_A570_L0.7400.65
324_P344_S0.7400.65
20_I24_S0.7390.65
366_E370_D0.7390.65
264_T359_A0.7370.65
305_D312_G0.7360.65
121_I169_V0.7360.65
142_L147_M0.7360.65
27_L30_V0.7350.65
334_E520_Q0.7310.65
136_S140_G0.7300.64
104_Y604_L0.7290.64
2_M14_L0.7290.64
416_T419_F0.7280.64
285_V288_E0.7260.64
315_M318_L0.7260.64
90_Q94_R0.7250.64
20_I25_F0.7230.64
259_H374_K0.7220.64
593_T597_A0.7220.64
247_V380_A0.7210.63
232_R415_Q0.7190.63
263_F367_V0.7190.63
283_K340_G0.7190.63
263_F371_I0.7190.63
290_N338_L0.7180.63
46_N99_A0.7170.63
275_Q305_D0.7160.63
379_K390_K0.7140.63
211_E487_K0.7130.63
509_D512_A0.7120.62
334_E353_L0.7110.62
103_Q106_R0.7110.62
100_L614_I0.7110.62
453_S465_V0.7090.62
305_D315_M0.7070.62
506_L590_Q0.7050.62
606_S610_K0.7040.62
273_I315_M0.7010.61
324_P328_K0.7000.61
124_T145_M0.7000.61
387_L390_K0.6990.61
500_K567_V0.6980.61
305_D349_L0.6980.61
418_W423_N0.6980.61
293_G298_L0.6970.61
147_M155_A0.6970.61
437_I466_L0.6950.61
521_A524_L0.6930.60
26_I395_A0.6930.60
227_T230_Q0.6930.60
393_D396_S0.6930.60
528_E534_R0.6920.60
16_I22_I0.6920.60
11_S24_S0.6900.60
274_I313_G0.6890.60
535_S538_D0.6890.60
305_D342_I0.6880.60
504_E559_M0.6870.60
607_N611_E0.6870.60
267_Q358_P0.6870.60
18_F225_F0.6870.60
269_T331_G0.6860.60
458_V462_R0.6860.60
424_L434_A0.6830.59
341_V350_I0.6830.59
275_Q327_L0.6820.59
278_T304_A0.6820.59
309_A312_G0.6790.59
273_I305_D0.6790.59
140_G143_N0.6780.59
250_A410_G0.6780.59
273_I303_S0.6780.59
364_L375_V0.6760.59
204_A491_Q0.6760.59
127_F131_G0.6750.58
235_Y466_L0.6730.58
364_L367_V0.6720.58
4_S7_T0.6720.58
91_V127_F0.6720.58
296_A312_G0.6710.58
505_K508_V0.6710.58
154_Q157_R0.6700.58
544_A547_L0.6700.58
314_D317_W0.6700.58
16_I19_G0.6690.58
287_D301_E0.6670.57
209_V487_K0.6660.57
323_I331_G0.6610.57
200_V495_A0.6610.57
459_D462_R0.6600.57
18_F24_S0.6580.56
191_R545_F0.6580.56
96_I614_I0.6570.56
289_L550_P0.6570.56
252_I368_R0.6570.56
492_H496_E0.6560.56
218_Y475_A0.6550.56
212_Q480_A0.6530.56
23_V27_L0.6520.56
50_I75_S0.6520.56
333_K340_G0.6520.56
218_Y222_K0.6510.56
315_M327_L0.6490.55
17_I28_T0.6490.55
75_S81_E0.6480.55
328_K332_L0.6470.55
203_L495_A0.6460.55
203_L206_K0.6460.55
526_F529_P0.6450.55
365_D484_E0.6440.55
206_K498_Q0.6430.55
267_Q320_D0.6430.55
508_V511_K0.6430.55
299_A309_A0.6420.55
318_L329_N0.6420.55
2_M18_F0.6420.55
149_A152_Y0.6420.55
14_L18_F0.6420.55
563_M566_N0.6400.54
248_S252_I0.6400.54
303_S312_G0.6380.54
458_V464_F0.6380.54
191_R269_T0.6370.54
231_F437_I0.6370.54
112_I161_T0.6370.54
155_A159_Q0.6340.54
6_R11_S0.6340.54
231_F421_K0.6330.54
419_F423_N0.6320.53
363_S369_D0.6320.53
271_Y327_L0.6320.53
540_I570_L0.6310.53
360_K366_E0.6310.53
274_I312_G0.6300.53
391_V402_L0.6290.53
315_M331_G0.6280.53
193_V540_I0.6270.53
268_R317_W0.6250.53
314_D355_D0.6250.53
24_S27_L0.6240.53
217_Y225_F0.6240.53
112_I258_Q0.6240.53
156_L159_Q0.6230.52
368_R371_I0.6210.52
421_K438_F0.6210.52
587_A591_G0.6200.52
232_R416_T0.6200.52
506_L569_L0.6190.52
272_S313_G0.6190.52
303_S349_L0.6180.52
326_E343_K0.6180.52
419_F437_I0.6170.52
152_Y156_L0.6160.52
602_E606_S0.6160.52
405_A408_A0.6160.52
255_Y262_Q0.6150.52
273_I313_G0.6150.52
274_I303_S0.6150.52
133_F142_L0.6140.51
253_Q260_Q0.6140.51
523_G528_E0.6140.51
510_L557_Y0.6130.51
241_A244_Q0.6110.51
598_Q602_E0.6110.51
514_K518_A0.6100.51
364_L372_A0.6100.51
274_I295_F0.6090.51
171_G175_M0.6090.51
392_S465_V0.6090.51
323_I328_K0.6070.51
53_G56_E0.6050.50
437_I458_V0.6040.50
46_N613_K0.6040.50
366_E371_I0.6040.50
594_Q598_Q0.6020.50
184_A188_A0.6020.50
248_S379_K0.6010.50
510_L515_G0.6010.50
419_F422_D0.6010.50
415_Q469_S0.6000.50
271_Y332_L0.5990.50
121_I133_F0.5970.49
18_F25_F0.5970.49
548_P556_S0.5960.49
279_E341_V0.5950.49
55_F92_L0.5940.49
394_A409_A0.5940.49
8_A24_S0.5920.49
205_A495_A0.5920.49
547_L558_G0.5910.49
256_Y362_K0.5900.49
112_I519_M0.5900.49
248_S262_Q0.5900.49
329_N337_Q0.5890.48
294_D352_R0.5880.48
335_K353_L0.5880.48
516_A519_M0.5880.48
248_S253_Q0.5870.48
209_V491_Q0.5850.48
108_L236_I0.5850.48
211_E245_Q0.5840.48
45_V69_Q0.5830.48
20_I105_A0.5820.48
18_F21_I0.5820.48
248_S255_Y0.5820.48
585_K589_V0.5810.48
168_G176_L0.5800.47
121_I138_Y0.5800.47
299_A303_S0.5790.47
273_I342_I0.5780.47
43_A96_I0.5770.47
209_V214_I0.5770.47
98_E162_T0.5770.47
3_D209_V0.5760.47
21_I26_I0.5760.47
288_E298_L0.5760.47
198_I203_L0.5750.47
472_K475_A0.5750.47
5_L8_A0.5740.47
196_A516_A0.5730.47
8_A15_K0.5720.47
91_V95_L0.5720.47
218_Y341_V0.5720.47
457_T463_A0.5720.47
275_Q324_P0.5700.46
249_D364_L0.5690.46
199_D566_N0.5690.46
431_K435_D0.5680.46
432_P435_D0.5680.46
225_F397_N0.5680.46
269_T353_L0.5670.46
223_N580_M0.5670.46
273_I312_G0.5660.46
210_T487_K0.5660.46
179_E596_N0.5660.46
384_Y388_Q0.5660.46
331_G351_V0.5640.46
145_M389_Q0.5640.46
397_N452_N0.5630.45
312_G349_L0.5630.45
272_S299_A0.5630.45
87_L90_Q0.5620.45
45_V103_Q0.5610.45
348_F499_A0.5610.45
250_A279_E0.5610.45
298_L303_S0.5610.45
100_L605_M0.5600.45
377_H380_A0.5590.45
113_S483_Q0.5590.45
389_Q393_D0.5590.45
427_E434_A0.5580.45
119_Q122_F0.5570.45
181_D580_M0.5570.45
36_G570_L0.5570.45
14_L24_S0.5560.45
7_T11_S0.5560.45
15_K22_I0.5550.45
247_V501_V0.5550.45
100_L612_A0.5540.44
283_K286_L0.5540.44
233_V419_F0.5530.44
298_L323_I0.5530.44
274_I285_V0.5510.44
185_A578_G0.5500.44
470_E518_A0.5500.44
372_A375_V0.5500.44
405_A409_A0.5490.44
539_P542_Q0.5490.44
94_R98_E0.5480.44
289_L499_A0.5480.44
208_P514_K0.5480.44
595_N599_I0.5470.44
248_S254_S0.5460.44
528_E531_T0.5450.43
324_P329_N0.5450.43
435_D439_N0.5440.43
532_L536_G0.5440.43
121_I576_K0.5440.43
418_W470_E0.5440.43
523_G534_R0.5440.43
161_T221_N0.5440.43
381_L437_I0.5430.43
121_I153_A0.5420.43
50_I478_P0.5410.43
183_L187_V0.5400.43
221_N486_V0.5400.43
315_M346_V0.5390.43
14_L23_V0.5390.43
278_T321_A0.5380.43
331_G339_S0.5380.43
254_S257_D0.5380.43
225_F482_V0.5380.43
392_S395_A0.5370.43
213_E402_L0.5370.43
164_Q168_G0.5370.43
244_Q376_K0.5360.42
13_V16_I0.5360.42
167_N595_N0.5360.42
319_E328_K0.5360.42
427_E433_V0.5360.42
394_A405_A0.5360.42
428_L434_A0.5360.42
483_Q486_V0.5360.42
167_N225_F0.5350.42
19_G22_I0.5340.42
42_A51_S0.5340.42
328_K331_G0.5330.42
480_A484_E0.5310.42
506_L519_M0.5310.42
197_T568_V0.5310.42
16_I96_I0.5310.42
396_S503_A0.5300.42
497_Q500_K0.5300.42
298_L301_E0.5290.42
107_E211_E0.5290.42
127_F137_R0.5290.42
146_G156_L0.5280.41
123_A160_L0.5280.41
516_A571_A0.5280.41
268_R319_E0.5270.41
586_K589_V0.5260.41
499_A567_V0.5260.41
157_R161_T0.5260.41
30_V44_K0.5260.41
193_V524_L0.5250.41
51_S481_D0.5250.41
5_L14_L0.5250.41
557_Y571_A0.5240.41
43_A55_F0.5240.41
294_D298_L0.5240.41
276_T304_A0.5240.41
281_E328_K0.5240.41
26_I31_S0.5230.41
526_F534_R0.5220.41
35_I110_L0.5210.41
362_K408_A0.5210.41
86_T209_V0.5210.41
585_K588_M0.5210.41
9_A14_L0.5200.41
299_A305_D0.5200.41
263_F369_D0.5200.41
225_F457_T0.5200.41
275_Q278_T0.5200.41
333_K338_L0.5200.41
271_Y349_L0.5200.41
147_M151_Q0.5190.40
48_Q109_K0.5190.40
131_G134_D0.5180.40
278_T524_L0.5180.40
275_Q313_G0.5180.40
590_Q594_Q0.5170.40
54_Q615_K0.5170.40
158_N413_A0.5170.40
35_I171_G0.5160.40
111_G161_T0.5160.40
391_V395_A0.5160.40
289_L387_L0.5150.40
212_Q368_R0.5140.40
509_D537_R0.5140.40
523_G529_P0.5140.40
69_Q93_N0.5130.40
285_V293_G0.5130.40
306_I346_V0.5130.40
112_I160_L0.5130.40
24_S29_G0.5120.40
105_A165_L0.5120.40
17_I293_G0.5120.40
304_A309_A0.5120.40
260_Q484_E0.5120.40
47_D313_G0.5110.40
365_D512_A0.5110.40
62_E66_M0.5110.40
208_P491_Q0.5100.39
251_D375_V0.5100.39
158_N350_I0.5100.39
191_R513_G0.5090.39
547_L551_A0.5090.39
275_Q323_I0.5090.39
299_A314_D0.5090.39
16_I598_Q0.5080.39
306_I309_A0.5080.39
192_V531_T0.5080.39
212_Q353_L0.5080.39
80_N236_I0.5070.39
306_I323_I0.5070.39
115_E118_K0.5070.39
62_E401_S0.5070.39
67_Q71_G0.5070.39
256_Y361_V0.5060.39
198_I503_A0.5050.39
231_F438_F0.5050.39
26_I497_Q0.5050.39
396_S452_N0.5050.39
17_I395_A0.5030.39
424_L427_E0.5030.39
60_N129_V0.5030.39
309_A354_D0.5030.39
48_Q583_D0.5020.39
333_K608_L0.5020.39
325_D328_K0.5020.39
376_K379_K0.5020.39
121_I459_D0.5020.39
56_E91_V0.5020.39
216_S221_N0.5010.38
175_M593_T0.5000.38
337_Q353_L0.5000.38
263_F266_P0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1m5yA 1 0.6051 100 0.611 Contact Map
3nrkA 3 0.4655 100 0.675 Contact Map
3rgcA 2 0.4013 100 0.721 Contact Map
4wo7A 2 0.4029 100 0.726 Contact Map
3rfwA 2 0.3917 100 0.728 Contact Map
3tc5A 1 0.1942 100 0.813 Contact Map
1yw5A 1 0.2681 100 0.82 Contact Map
2kgjA 1 0.1621 99.9 0.83 Contact Map
3i6cA 1 0.1445 99.9 0.833 Contact Map
2m08A 1 0.1477 99.9 0.835 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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