GREMLIN Database
YGIB - UPF0441 protein YgiB
UniProt: P0ADT2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11164
Length: 223 (181)
Sequences: 290 (200)
Seq/√Len: 14.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
82_Y197_G3.9521.00
129_Y133_R3.4380.99
205_K209_M3.3230.99
125_L132_G3.2200.99
47_Y165_G2.8140.97
48_Q52_D2.6330.95
82_Y91_E2.5510.94
83_A130_M2.3300.91
17_S27_A2.3050.90
121_F125_L2.2950.90
50_A54_S2.1370.86
205_K210_Q2.1290.86
74_E77_R2.1260.86
123_M130_M2.1220.86
124_P129_Y2.1100.86
168_Y203_V2.1090.86
54_S65_T2.0650.84
144_Q149_S2.0610.84
47_Y160_Y2.0490.84
47_Y59_G1.9150.80
92_F203_V1.8710.78
93_G124_P1.8200.76
68_Y72_L1.7770.74
120_S137_G1.7450.73
30_T140_G1.7320.72
201_E205_K1.7260.72
190_T201_E1.7260.72
91_E151_N1.7180.71
29_A138_G1.6840.70
83_A86_E1.6250.67
29_A174_G1.6170.67
89_V162_D1.6130.66
49_N52_D1.6110.66
44_V122_W1.6090.66
205_K211_R1.5890.65
51_D73_K1.5870.65
27_A207_S1.5510.63
75_A147_F1.5500.63
69_N122_W1.4780.59
102_A132_G1.4660.59
30_T65_T1.4460.58
23_P75_A1.4220.56
132_G135_M1.4100.56
91_E190_T1.3920.55
196_R206_Q1.3840.54
48_Q132_G1.3630.53
53_C88_C1.3380.52
53_C64_C1.3380.52
64_C88_C1.3380.52
193_T196_R1.3260.51
19_R22_T1.3160.51
17_S20_H1.3140.50
24_V50_A1.2710.48
125_L135_M1.2690.48
145_P203_V1.2640.48
40_S62_A1.2620.48
34_L89_V1.2420.46
164_T194_V1.2280.46
74_E188_P1.2110.45
71_A97_C1.2020.44
208_T211_R1.1900.44
50_A175_R1.1790.43
33_M36_G1.1690.42
52_D152_P1.1670.42
127_A148_S1.1660.42
47_Y151_N1.1590.42
38_E164_T1.1490.41
123_M134_L1.1400.41
93_G130_M1.1240.40
125_L129_Y1.1230.40
52_D180_P1.1140.39
92_F179_V1.1110.39
100_A125_L1.1030.39
161_T203_V1.1000.39
69_N72_L1.0980.39
24_V203_V1.0960.38
53_C97_C1.0890.38
64_C97_C1.0890.38
88_C97_C1.0890.38
49_N194_V1.0880.38
130_M191_T1.0820.38
38_E205_K1.0770.37
53_C198_G1.0750.37
88_C198_G1.0750.37
64_C198_G1.0750.37
78_T91_E1.0420.36
84_T87_D1.0320.35
147_F151_N1.0280.35
127_A131_M1.0250.35
87_D91_E1.0230.35
175_R184_M1.0050.34
40_S61_S1.0030.34
126_M193_T0.9950.33
122_W129_Y0.9940.33
17_S22_T0.9770.32
75_A203_V0.9740.32
40_S84_T0.9730.32
17_S90_A0.9710.32
121_F127_A0.9670.32
33_M86_E0.9660.32
55_A61_S0.9640.32
191_T206_Q0.9620.32
62_A140_G0.9570.31
70_N192_T0.9520.31
23_P68_Y0.9480.31
19_R27_A0.9410.31
94_E208_T0.9400.31
128_G198_G0.9310.30
51_D55_A0.9290.30
132_G142_A0.9290.30
95_G173_P0.9270.30
75_A145_P0.9240.30
80_P128_G0.9070.29
85_R170_A0.9060.29
206_Q209_M0.8970.29
24_V30_T0.8950.28
134_L137_G0.8900.28
122_W189_A0.8880.28
100_A148_S0.8870.28
79_A199_F0.8840.28
193_T209_M0.8830.28
33_M90_A0.8770.28
93_G122_W0.8760.28
73_K76_E0.8680.27
16_W24_V0.8670.27
24_V27_A0.8640.27
52_D196_R0.8630.27
68_Y158_G0.8600.27
206_Q211_R0.8380.26
17_S191_T0.8290.26
97_C198_G0.8230.25
75_A158_G0.8200.25
93_G132_G0.8120.25
86_E150_K0.8110.25
37_C134_L0.8050.25
76_E95_G0.8040.25
70_N99_Q0.8040.25
36_G204_A0.7980.24
188_P191_T0.7980.24
82_Y199_F0.7930.24
201_E209_M0.7870.24
86_E98_Q0.7830.24
199_F208_T0.7800.24
75_A164_T0.7760.23
154_S161_T0.7740.23
43_T189_A0.7730.23
18_A23_P0.7710.23
172_Q175_R0.7690.23
164_T206_Q0.7690.23
46_L122_W0.7650.23
43_T210_Q0.7650.23
21_L25_A0.7640.23
26_L101_P0.7630.23
50_A210_Q0.7580.23
48_Q63_E0.7580.23
56_A166_K0.7550.23
19_R23_P0.7530.22
47_Y56_A0.7520.22
81_K149_S0.7510.22
25_A130_M0.7510.22
163_A188_P0.7410.22
68_Y82_Y0.7350.22
28_V186_P0.7330.22
86_E134_L0.7320.22
73_K85_R0.7280.22
58_P154_S0.7270.21
101_P204_A0.7250.21
17_S91_E0.7250.21
31_V131_M0.7220.21
22_T27_A0.7220.21
64_C200_G0.7220.21
88_C200_G0.7220.21
53_C200_G0.7220.21
132_G136_G0.7210.21
50_A60_K0.7210.21
68_Y190_T0.7170.21
143_Q195_T0.7140.21
36_G192_T0.7140.21
131_M204_A0.7100.21
181_K204_A0.7100.21
70_N85_R0.7090.21
20_H83_A0.7060.21
154_S177_M0.7030.21
20_H77_R0.7020.21
162_D168_Y0.6980.20
76_E84_T0.6970.20
62_A125_L0.6880.20
67_A176_T0.6770.20
55_A84_T0.6690.19
26_L192_T0.6660.19
64_C128_G0.6640.19
88_C128_G0.6640.19
53_C128_G0.6640.19
158_G171_A0.6620.19
29_A204_A0.6600.19
93_G162_D0.6590.19
122_W125_L0.6560.19
186_P201_E0.6560.19
67_A199_F0.6540.19
32_F173_P0.6520.19
80_P200_G0.6490.19
158_G204_A0.6460.19
29_A129_Y0.6450.19
52_D187_K0.6390.18
33_M129_Y0.6330.18
195_T204_A0.6310.18
64_C199_F0.6310.18
53_C199_F0.6310.18
88_C199_F0.6310.18
16_W147_F0.6300.18
86_E201_E0.6290.18
131_M147_F0.6270.18
63_E160_Y0.6200.18
87_D189_A0.6180.18
175_R202_S0.6160.18
54_S150_K0.6160.18
31_V94_E0.6150.18
36_G181_K0.6150.18
26_L31_V0.6140.18
149_S160_Y0.6110.17
163_A182_T0.6100.17
71_A200_G0.6070.17
33_M189_A0.6060.17
34_L51_D0.6020.17
51_D61_S0.5990.17
123_M186_P0.5980.17
149_S154_S0.5980.17
148_S151_N0.5970.17
143_Q168_Y0.5960.17
154_S165_G0.5940.17
80_P92_F0.5890.17
36_G51_D0.5890.17
127_A147_F0.5840.17
21_L140_G0.5840.17
22_T59_G0.5840.17
20_H191_T0.5810.16
93_G123_M0.5800.16
94_E136_G0.5780.16
20_H118_S0.5770.16
68_Y169_G0.5730.16
42_E68_Y0.5710.16
162_D166_K0.5710.16
28_V31_V0.5680.16
102_A123_M0.5660.16
28_V42_E0.5640.16
38_E137_G0.5630.16
123_M132_G0.5570.16
74_E78_T0.5550.16
78_T87_D0.5540.16
133_R204_A0.5520.16
65_T69_N0.5520.16
43_T164_T0.5490.16
43_T211_R0.5410.15
60_K66_T0.5410.15
95_G211_R0.5390.15
62_A85_R0.5390.15
16_W22_T0.5380.15
52_D134_L0.5340.15
58_P190_T0.5320.15
73_K138_G0.5290.15
135_M207_S0.5260.15
130_M171_A0.5260.15
42_E93_G0.5220.15
144_Q178_T0.5170.15
125_L172_Q0.5170.15
141_F151_N0.5150.15
84_T191_T0.5110.14
36_G135_M0.5080.14
52_D175_R0.5070.14
93_G96_Q0.5060.14
50_A193_T0.5000.14
126_M178_T0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pk2A 3 0.3901 8.4 0.965 Contact Map
2vdaB 1 0.1256 6.8 0.966 Contact Map
4r2fA 1 0.6996 6.5 0.967 Contact Map
1zuoA 3 0.2915 4.8 0.968 Contact Map
1jatA 1 0.3274 4.5 0.969 Contact Map
3woaA 1 0.8251 4 0.97 Contact Map
2bepA 1 0.3184 3.9 0.97 Contact Map
4zr7A 1 0.1883 3.7 0.97 Contact Map
2daeA 1 0.2825 3.4 0.971 Contact Map
3zbiC 1 0.1211 2.9 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0077 seconds.