GREMLIN Database
YQAA - Inner membrane protein YqaA
UniProt: P0ADR0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13529
Length: 142 (129)
Sequences: 1016 (720)
Seq/√Len: 63.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
48_T124_A7.1971.00
15_F57_T5.5571.00
52_S120_C4.5041.00
44_V131_A3.4041.00
115_V119_L2.9661.00
44_V128_V2.4461.00
92_S122_G2.4431.00
86_A114_P2.3241.00
11_F50_G2.2801.00
30_V134_T2.1551.00
58_N102_C2.0961.00
17_S23_G1.9531.00
13_S28_V1.9391.00
56_L112_W1.9351.00
55_G119_L1.8671.00
33_L131_A1.8651.00
59_V112_W1.8211.00
57_T61_L1.7881.00
30_V130_V1.7180.99
33_L40_P1.6610.99
111_S114_P1.6460.99
97_V100_L1.5320.99
32_M43_L1.4840.98
20_L103_L1.4520.98
128_V132_A1.4410.98
89_L105_A1.4210.98
48_T52_S1.3760.97
37_I40_P1.3720.97
11_F53_L1.3160.96
60_I64_F1.3120.96
91_L94_M1.3050.96
90_L118_F1.2950.96
117_F121_L1.2580.95
75_E78_T1.2500.95
44_V124_A1.2410.95
58_N103_L1.2310.95
18_A99_D1.2270.95
30_V34_L1.2250.95
130_V134_T1.2210.94
29_L43_L1.1970.94
81_L110_I1.1960.94
56_L116_I1.1630.93
90_L93_W1.1580.93
112_W116_I1.1380.92
16_L94_M1.1250.92
13_S23_G1.1190.91
125_L128_V1.0950.91
6_S9_S1.0930.90
76_K80_W1.0860.90
131_A135_V1.0810.90
66_P69_K1.0660.89
74_Q107_W1.0580.89
122_G125_L1.0530.89
116_I120_C1.0510.89
78_T108_M1.0450.88
86_A118_F1.0350.88
10_L29_L1.0300.88
16_L23_G1.0220.87
52_S124_A1.0070.86
81_L92_S1.0000.86
27_V30_V1.0000.86
10_L32_M0.9820.85
81_L88_T0.9790.85
34_L134_T0.9790.85
90_L121_L0.9790.85
45_L49_M0.9770.85
113_G117_F0.9710.84
55_G92_S0.9540.83
46_T49_M0.9510.83
68_R71_S0.9260.81
18_A58_N0.9210.81
81_L115_V0.9080.80
33_L134_T0.9030.80
60_I63_R0.9010.80
75_E79_G0.8990.80
67_L109_R0.8930.79
67_L72_R0.8810.78
31_A35_S0.8750.78
86_A110_I0.8590.76
9_S13_S0.8580.76
70_T73_W0.8510.76
16_L21_L0.8440.75
15_F53_L0.8440.75
96_V100_L0.8410.75
49_M120_C0.8390.75
54_G123_K0.8380.75
94_M97_V0.8340.74
87_V118_F0.8220.73
56_L119_L0.8210.73
92_S102_C0.8200.73
93_W105_A0.8110.72
67_L71_S0.8100.72
20_L100_L0.8070.72
131_A134_T0.7890.70
112_W115_V0.7850.70
20_L99_D0.7830.69
94_M129_A0.7720.68
12_A132_A0.7690.68
111_S116_I0.7600.67
17_S78_T0.7590.67
7_L23_G0.7580.67
17_S24_N0.7560.67
81_L102_C0.7530.66
74_Q78_T0.7500.66
77_A100_L0.7460.66
14_S55_G0.7400.65
81_L119_L0.7390.65
26_E127_Y0.7380.65
54_G122_G0.7350.65
120_C124_A0.7350.65
75_E132_A0.7310.64
29_L59_V0.7230.63
59_V114_P0.7230.63
14_S60_I0.7200.63
55_G115_V0.7100.62
110_I122_G0.7030.61
68_R72_R0.7020.61
94_M122_G0.6880.59
20_L57_T0.6830.59
124_A128_V0.6830.59
48_T120_C0.6800.59
56_L111_S0.6760.58
17_S31_A0.6730.58
68_R73_W0.6690.57
59_V110_I0.6660.57
25_S127_Y0.6640.57
55_G105_A0.6590.56
14_S61_L0.6580.56
92_S101_L0.6470.55
7_L39_H0.6410.54
107_W110_I0.6400.54
6_S12_A0.6370.54
66_P78_T0.6370.54
33_L97_V0.6340.53
33_L135_V0.6280.53
39_H42_V0.6260.52
76_K82_K0.6230.52
113_G116_I0.6140.51
102_C119_L0.6140.51
13_S17_S0.6060.50
14_S28_V0.6060.50
6_S42_V0.6040.50
24_N122_G0.5980.49
57_T102_C0.5930.49
24_N27_V0.5900.48
59_V111_S0.5890.48
51_N126_R0.5880.48
69_K73_W0.5850.48
69_K75_E0.5780.47
74_Q86_A0.5780.47
58_N61_L0.5720.46
29_L130_V0.5670.46
28_V44_V0.5640.45
18_A29_L0.5630.45
6_S48_T0.5630.45
100_L104_L0.5620.45
100_L115_V0.5620.45
23_G66_P0.5600.45
25_S123_K0.5580.45
23_G33_L0.5560.44
41_W128_V0.5550.44
89_L115_V0.5500.44
50_G53_L0.5500.44
57_T100_L0.5440.43
118_F122_G0.5430.43
53_L56_L0.5430.43
30_V33_L0.5420.43
64_F109_R0.5400.43
12_A42_V0.5350.42
130_V135_V0.5340.42
17_S76_K0.5340.42
91_L122_G0.5330.42
23_G96_V0.5330.42
10_L43_L0.5320.42
11_F46_T0.5310.41
31_A42_V0.5310.41
72_R75_E0.5290.41
27_V31_A0.5280.41
14_S47_A0.5270.41
20_L92_S0.5270.41
82_K94_M0.5240.41
80_W97_V0.5240.41
37_I121_L0.5220.40
129_A133_A0.5190.40
56_L118_F0.5150.40
86_A103_L0.5150.40
39_H131_A0.5140.40
45_L124_A0.5130.39
59_V115_V0.5110.39
70_T91_L0.5090.39
32_M89_L0.5060.39
42_V49_M0.5030.38
23_G63_R0.5030.38
40_P131_A0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3kcuA 3 0.4718 24.6 0.94 Contact Map
3klyA 3 0.4789 19.6 0.943 Contact Map
4fc4A 3 0.3873 18.8 0.944 Contact Map
3tdsE 3 0.4859 11.7 0.949 Contact Map
2jlnA 1 0.9507 9.2 0.951 Contact Map
2kncA 1 0.3521 3 0.961 Contact Map
1cp2A 2 0.5211 2.7 0.962 Contact Map
2m20A 2 0.338 2.6 0.962 Contact Map
4huqS 1 0.5423 2.6 0.962 Contact Map
2kv5A 1 0.2324 2.4 0.963 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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