GREMLIN Database
YIDX - Uncharacterized protein YidX
UniProt: P0ADM6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11719
Length: 218 (199)
Sequences: 105 (73)
Seq/√Len: 5.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_V195_L4.4980.95
175_V178_Y2.9680.71
52_S155_H2.8520.68
205_T209_Q2.7660.65
82_V195_L2.6250.61
60_T198_T2.3910.53
52_S64_V2.3450.52
64_V120_Y2.3330.51
68_E85_L2.3220.51
169_F178_Y2.2130.47
51_L62_G2.1920.47
23_G198_T2.1800.46
84_M208_L2.1190.44
51_L65_F1.8880.37
23_G180_Y1.8830.37
169_F175_V1.8780.37
22_S210_F1.8700.36
67_G196_P1.8640.36
154_I189_G1.8630.36
112_F152_G1.8630.36
112_F194_L1.8530.36
169_F173_F1.7670.33
114_G194_L1.7070.32
81_I85_L1.7060.32
48_I61_K1.6590.30
17_L56_D1.6550.30
138_C209_Q1.6150.29
109_K145_R1.6080.29
103_F114_G1.6030.29
44_Q154_I1.5990.29
11_A15_F1.5450.27
62_G65_F1.5410.27
173_F178_Y1.5270.27
12_A17_L1.5120.26
11_A19_L1.5000.26
72_Y77_G1.4910.26
181_Y210_F1.4890.26
71_D195_L1.4870.26
22_S204_I1.4800.26
46_D152_G1.4640.25
50_G193_A1.4610.25
196_P202_D1.4560.25
67_G202_D1.4560.25
77_G114_G1.4530.25
90_L192_A1.4360.24
145_R160_N1.4220.24
110_K173_F1.4160.24
11_A17_L1.4140.24
198_T203_I1.3800.23
73_L155_H1.3710.23
31_S211_L1.3710.23
52_S69_S1.3580.23
72_Y130_L1.3570.23
13_G204_I1.3420.22
62_G73_L1.3160.22
38_S203_I1.2890.21
13_G45_S1.2840.21
63_Y66_V1.2770.21
82_V209_Q1.2730.21
46_D196_P1.2700.21
46_D67_G1.2700.21
77_G103_F1.2480.20
14_L97_V1.2480.20
44_Q48_I1.2240.20
68_E210_F1.2200.20
29_L74_I1.2100.19
164_S175_V1.2000.19
41_Y84_M1.1810.19
172_P205_T1.1800.19
40_K43_S1.1770.19
150_L199_V1.1690.19
121_Y190_V1.1650.18
116_I200_T1.1500.18
21_L24_C1.1480.18
52_S120_Y1.1390.18
93_H110_K1.1380.18
74_I207_P1.1330.18
128_K184_R1.1260.18
64_V96_Q1.1250.18
154_I157_K1.1210.18
143_C209_Q1.1200.18
18_A210_F1.1160.18
23_G152_G1.1160.18
24_C67_G1.1130.17
24_C196_P1.1130.17
44_Q69_S1.1020.17
59_G169_F1.1020.17
173_F177_F1.0990.17
171_H175_V1.0960.17
51_L73_L1.0890.17
81_I136_F1.0880.17
65_F90_L1.0830.17
77_G135_G1.0710.17
36_G203_I1.0670.17
203_I208_L1.0670.17
64_V201_L1.0650.17
66_V103_F1.0520.16
200_T204_I1.0460.16
154_I159_K1.0420.16
25_I201_L1.0410.16
42_Q76_D1.0380.16
31_S39_G1.0330.16
64_V155_H1.0270.16
11_A43_S1.0230.16
95_I134_Y1.0200.16
146_S154_I1.0190.16
26_S30_V1.0170.16
22_S66_V1.0140.16
22_S165_K1.0140.16
117_S147_L1.0070.16
84_M195_L1.0060.16
108_G179_E1.0010.15
67_G207_P0.9930.15
196_P207_P0.9930.15
15_F64_V0.9920.15
82_V105_L0.9910.15
147_L199_V0.9770.15
14_L75_T0.9770.15
51_L120_Y0.9760.15
85_L158_N0.9720.15
77_G150_L0.9590.15
64_V73_L0.9590.15
12_A204_I0.9510.15
151_K197_V0.9480.15
201_L205_T0.9460.15
33_T191_S0.9460.15
110_K143_C0.9450.15
26_S131_A0.9450.15
23_G182_S0.9440.15
62_G136_F0.9440.15
47_T131_A0.9390.14
76_D116_I0.9320.14
79_D149_N0.9270.14
80_D127_E0.9180.14
26_S38_S0.9180.14
12_A133_H0.9150.14
115_T181_Y0.9150.14
73_L192_A0.9140.14
135_G151_K0.9050.14
30_V145_R0.9000.14
192_A195_L0.8970.14
126_E165_K0.8970.14
155_H169_F0.8910.14
31_S205_T0.8870.14
93_H96_Q0.8850.14
70_L118_L0.8760.13
110_K193_A0.8730.13
14_L29_L0.8730.13
26_S40_K0.8720.13
73_L205_T0.8710.13
31_S128_K0.8670.13
94_N175_V0.8670.13
15_F60_T0.8650.13
52_S175_V0.8650.13
65_F77_G0.8640.13
147_L150_L0.8610.13
115_T154_I0.8600.13
38_S199_V0.8580.13
91_N102_R0.8560.13
26_S198_T0.8480.13
146_S210_F0.8470.13
152_G196_P0.8420.13
67_G152_G0.8420.13
30_V205_T0.8370.13
80_D186_I0.8350.13
52_S71_D0.8310.13
102_R136_F0.8280.13
47_T104_V0.8180.13
151_K181_Y0.8180.13
182_S188_D0.8150.13
15_F22_S0.8120.12
65_F73_L0.8070.12
17_L42_Q0.8050.12
23_G86_N0.8040.12
46_D74_I0.8020.12
70_L90_L0.8010.12
72_Y196_P0.7970.12
67_G72_Y0.7970.12
120_Y155_H0.7930.12
46_D202_D0.7890.12
131_A134_Y0.7820.12
12_A15_F0.7770.12
46_D72_Y0.7750.12
14_L99_D0.7740.12
23_G125_E0.7730.12
48_I193_A0.7710.12
72_Y204_I0.7670.12
120_Y211_L0.7640.12
143_C191_S0.7630.12
47_T172_P0.7580.12
158_N165_K0.7560.12
37_S106_N0.7530.12
50_G133_H0.7520.12
23_G41_Y0.7490.12
63_Y139_G0.7490.12
170_Y191_S0.7370.11
77_G152_G0.7340.11
53_Q192_A0.7320.11
37_S151_K0.7310.11
78_A132_T0.7280.11
60_T119_Y0.7250.11
138_C172_P0.7240.11
14_L188_D0.7230.11
118_L172_P0.7220.11
131_A208_L0.7170.11
40_K132_T0.7110.11
190_V212_V0.7110.11
14_L40_K0.7090.11
150_L207_P0.7030.11
114_G195_L0.7030.11
69_S146_S0.6990.11
16_P139_G0.6980.11
194_L204_I0.6930.11
128_K192_A0.6840.11
60_T204_I0.6830.11
76_D204_I0.6830.11
111_K154_I0.6660.11
72_Y154_I0.6610.10
20_M44_Q0.6600.10
26_S118_L0.6600.10
184_R208_L0.6590.10
63_Y187_P0.6550.10
133_H161_M0.6540.10
14_L172_P0.6540.10
21_L149_N0.6530.10
180_Y186_I0.6530.10
167_M171_H0.6530.10
79_D197_V0.6490.10
17_L20_M0.6460.10
39_G197_V0.6460.10
80_D135_G0.6450.10
26_S201_L0.6420.10
24_C202_D0.6420.10
26_S31_S0.6310.10
33_T74_I0.6300.10
50_G86_N0.6270.10
26_S29_L0.6260.10
12_A139_G0.6250.10
127_E211_L0.6210.10
39_G79_D0.6210.10
105_L179_E0.6200.10
91_N150_L0.6190.10
20_M102_R0.6180.10
114_G120_Y0.6170.10
91_N107_A0.6160.10
134_Y144_T0.6130.10
78_A106_N0.6120.10
12_A23_G0.6100.10
131_A136_F0.6090.10
71_D155_H0.6080.10
52_S177_F0.6080.10
23_G197_V0.6040.10
199_V210_F0.5970.10
41_Y45_S0.5940.10
127_E185_G0.5820.10
39_G187_P0.5780.09
81_I87_D0.5770.09
30_V191_S0.5770.09
62_G96_Q0.5730.09
22_S123_N0.5670.09
182_S200_T0.5660.09
12_A18_A0.5640.09
179_E193_A0.5630.09
29_L105_L0.5610.09
117_S125_E0.5600.09
76_D199_V0.5590.09
155_H192_A0.5550.09
65_F157_K0.5550.09
21_L36_G0.5520.09
14_L159_K0.5490.09
71_D114_G0.5490.09
87_D158_N0.5480.09
23_G173_F0.5450.09
30_V84_M0.5430.09
15_F40_K0.5430.09
59_G156_E0.5420.09
32_H48_I0.5410.09
28_A105_L0.5390.09
155_H171_H0.5370.09
43_S181_Y0.5360.09
114_G141_Q0.5340.09
149_N197_V0.5310.09
80_D153_T0.5250.09
75_T175_V0.5210.09
150_L192_A0.5190.09
48_I116_I0.5160.09
151_K199_V0.5150.09
107_A212_V0.5130.09
85_L139_G0.5100.09
87_D166_V0.5090.09
71_D169_F0.5090.09
13_G212_V0.5060.09
35_K113_T0.5020.09
135_G204_I0.5010.09
91_N127_E0.5010.09
25_I198_T0.5000.09
26_S93_H0.5000.09
167_M173_F0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zbiC 1 0.1284 17.9 0.958 Contact Map
4lmhA 3 0.6193 14 0.96 Contact Map
2g5gX 1 0.7982 10.3 0.962 Contact Map
4eybA 2 0.789 8.4 0.964 Contact Map
1wteA 2 0.5642 7.4 0.965 Contact Map
4i62A 1 0.7202 4.5 0.968 Contact Map
4n4rB 1 0.6009 4.4 0.968 Contact Map
1p9eA 3 0.789 3.3 0.97 Contact Map
3ekiA 1 0.5688 3.2 0.97 Contact Map
4jg9A 2 0.4587 3.2 0.97 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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