GREMLIN Database
EDD - Phosphogluconate dehydratase
UniProt: P0ADF6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG10257
Length: 603 (540)
Sequences: 4834 (1952)
Seq/√Len: 84.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
445_E545_R4.4881.00
537_K566_E4.3411.00
282_I287_V3.8701.00
285_K367_H3.7051.00
545_R556_L3.6191.00
537_K562_L3.5841.00
445_E556_L3.5691.00
288_V367_H3.3921.00
468_R503_K3.2911.00
445_E543_I3.2441.00
277_P280_K3.2421.00
539_R568_H3.2111.00
547_N550_T3.1531.00
147_G269_T3.0481.00
368_E379_S2.9011.00
538_V555_L2.8611.00
361_L368_E2.8411.00
203_D206_A2.8011.00
170_H279_G2.7011.00
170_H280_K2.6841.00
543_I556_L2.6571.00
272_G277_P2.6161.00
408_A412_Q2.5971.00
68_I147_G2.5711.00
449_V470_C2.5471.00
545_R554_T2.5431.00
282_I286_V2.4501.00
449_V540_D2.4431.00
374_A381_Y2.4321.00
447_P543_I2.4231.00
166_L282_I2.4151.00
480_K531_D2.4061.00
539_R561_E2.3831.00
321_D424_S2.3661.00
558_D561_E2.3591.00
239_M282_I2.3401.00
561_E564_A2.3311.00
264_Q267_R2.3091.00
176_V261_A2.3091.00
293_A357_V2.3031.00
162_T239_M2.2981.00
453_S456_D2.2531.00
292_V329_V2.2231.00
194_R515_A2.2131.00
426_N554_T2.2011.00
324_S328_D2.2001.00
174_V265_V2.1871.00
285_K369_D2.1511.00
430_A553_L2.1401.00
246_F344_I2.1331.00
507_V525_V2.1311.00
443_V547_N2.1031.00
72_T104_V2.0951.00
376_F380_R2.0941.00
291_I323_F2.0851.00
162_T310_M2.0841.00
452_E475_R2.0761.00
292_V330_V2.0641.00
559_E563_A2.0551.00
54_P212_A2.0491.00
54_P60_L2.0471.00
295_L326_L2.0011.00
271_N276_M1.9981.00
370_V378_L1.9951.00
442_Q549_Q1.9741.00
557_V562_L1.9681.00
182_A250_D1.9591.00
68_I269_T1.9551.00
284_E288_V1.9471.00
319_N322_D1.8971.00
576_R580_G1.8751.00
324_S551_G1.8741.00
427_L538_V1.8661.00
260_A263_R1.8511.00
564_A567_P1.8471.00
267_R270_G1.8421.00
538_V544_I1.8281.00
150_F173_A1.8271.00
569_I572_L1.8221.00
555_L562_L1.8141.00
377_G380_R1.7871.00
234_V240_Q1.7841.00
100_A266_T1.7711.00
564_A568_H1.7531.00
253_L348_Q1.7461.00
538_V557_V1.7451.00
174_V264_Q1.7441.00
357_V378_L1.7401.00
166_L314_A1.7331.00
288_V325_D1.7321.00
452_E456_D1.7291.00
421_K551_G1.7281.00
267_R271_N1.7051.00
562_L566_E1.6911.00
443_V549_Q1.6881.00
97_E263_R1.6851.00
585_S589_E1.6571.00
165_A173_A1.6371.00
147_G265_V1.6341.00
240_Q244_S1.6301.00
357_V383_L1.6261.00
563_A567_P1.6241.00
174_V373_V1.6201.00
291_I318_I1.6161.00
196_L201_K1.6141.00
534_L562_L1.6071.00
183_S345_N1.6031.00
459_P463_A1.6001.00
95_L100_A1.5941.00
429_R433_K1.5931.00
292_V326_L1.5881.00
202_V206_A1.5781.00
229_T299_G1.5771.00
86_H255_D1.5731.00
444_I447_P1.5651.00
140_L148_A1.5591.00
452_E476_H1.5551.00
70_I95_L1.5481.00
38_S42_C1.5301.00
268_M276_M1.5301.00
443_V545_R1.5191.00
447_P470_C1.5110.99
526_T595_E1.5090.99
236_F293_A1.5030.99
450_V538_V1.4960.99
289_N370_V1.4760.99
448_A544_I1.4680.99
328_D417_H1.4670.99
96_H102_G1.4630.99
244_S257_L1.4630.99
78_L110_A1.4520.99
325_D329_V1.4430.99
359_E362_K1.4390.99
90_I259_A1.4340.99
554_T559_E1.4270.99
451_F460_A1.4250.99
451_F465_L1.4250.99
536_A569_I1.4210.99
284_E322_D1.4200.99
322_D325_D1.4060.99
460_A466_L1.3930.99
186_P206_A1.3930.99
89_E93_K1.3820.99
342_A405_N1.3820.99
563_A566_E1.3740.99
312_R596_Q1.3670.99
60_L208_L1.3650.99
376_F381_Y1.3650.99
448_A538_V1.3620.99
557_V561_E1.3610.99
71_I139_G1.3600.99
88_P151_L1.3580.99
163_M313_A1.3550.99
62_S65_R1.3520.99
239_M278_I1.3520.99
91_I149_L1.3490.99
285_K288_V1.3410.99
464_G500_R1.3400.99
430_A433_K1.3350.99
335_R341_P1.3340.99
282_I314_A1.3300.99
321_D325_D1.3230.99
164_A278_I1.3220.99
431_V435_S1.3220.99
229_T303_H1.3120.99
307_L318_I1.3040.98
84_Y153_V1.3030.98
304_T308_V1.2950.98
363_A410_F1.2900.98
93_K96_H1.2900.98
456_D459_P1.2790.98
76_D92_R1.2780.98
347_F356_L1.2670.98
90_I255_D1.2530.98
404_S412_Q1.2490.98
429_R435_S1.2470.98
94_A262_A1.2460.98
359_E404_S1.2460.98
111_M142_H1.2440.98
281_M286_V1.2420.98
68_I95_L1.2360.98
284_E325_D1.2300.98
95_L262_A1.2260.98
85_E89_E1.2250.98
287_V310_M1.2240.98
209_E213_A1.2170.98
162_T234_V1.2160.98
236_F357_V1.2140.98
455_H459_P1.2140.98
473_V538_V1.2130.98
401_S404_S1.2110.98
264_Q271_N1.2100.97
58_A103_Q1.2070.97
577_V580_G1.2060.97
170_H277_P1.2020.97
468_R499_D1.1950.97
149_L265_V1.1950.97
149_L262_A1.1890.97
537_K557_V1.1870.97
473_V544_I1.1860.97
443_V550_T1.1850.97
449_V467_D1.1830.97
191_V210_S1.1830.97
67_N103_Q1.1780.97
77_M145_F1.1780.97
366_L378_L1.1720.97
69_A140_L1.1680.97
592_S596_Q1.1670.97
97_E259_A1.1590.97
166_L239_M1.1570.97
361_L366_L1.1560.97
433_K436_A1.1550.97
526_T593_G1.1550.97
426_N559_E1.1460.97
450_V540_D1.1420.96
69_A148_A1.1330.96
409_S412_Q1.1260.96
317_Q596_Q1.1210.96
361_L379_S1.1190.96
164_A168_F1.1190.96
150_F175_F1.1180.96
90_I93_K1.1130.96
185_L190_K1.1050.96
58_A101_V1.1040.96
74_Y85_E1.1030.96
332_L415_S1.0940.95
537_K569_I1.0930.95
449_V460_A1.0930.95
71_I148_A1.0910.95
187_N206_A1.0870.95
177_P244_S1.0840.95
38_S41_A1.0780.95
470_C540_D1.0780.95
535_L538_V1.0740.95
50_A211_E1.0740.95
136_A164_A1.0720.95
284_E317_Q1.0710.95
455_H488_H1.0700.95
40_L53_Q1.0700.95
432_M546_V1.0640.95
109_P135_S1.0630.95
246_F348_Q1.0610.95
86_H89_E1.0600.95
192_R343_D1.0550.94
358_R398_A1.0520.94
208_L212_A1.0480.94
237_M287_V1.0460.94
377_G381_Y1.0460.94
123_E488_H1.0440.94
152_G158_V1.0410.94
593_G596_Q1.0400.94
505_A546_V1.0400.94
534_L566_E1.0380.94
280_K371_N1.0350.94
447_P467_D1.0340.94
288_V322_D1.0300.94
187_N209_E1.0290.94
452_E539_R1.0260.94
426_N555_L1.0240.94
429_R436_A1.0230.93
182_A251_S1.0190.93
60_L212_A1.0180.93
247_V251_S1.0130.93
94_A97_E1.0110.93
427_L534_L1.0060.93
242_P381_Y0.9960.93
361_L384_E0.9910.92
534_L555_L0.9850.92
572_L576_R0.9820.92
449_V466_L0.9820.92
182_A217_A0.9760.92
361_L383_L0.9730.92
305_M308_V0.9660.91
93_K259_A0.9660.91
264_Q268_M0.9650.91
566_E569_I0.9620.91
363_A411_E0.9610.91
466_L472_V0.9610.91
276_M371_N0.9590.91
217_A252_P0.9570.91
73_S161_L0.9540.91
557_V566_E0.9530.91
294_L303_H0.9510.91
150_F165_A0.9450.90
467_D470_C0.9440.90
284_E316_I0.9420.90
378_L381_Y0.9410.90
358_R399_E0.9390.90
421_K549_Q0.9380.90
43_G119_Q0.9360.90
472_V497_L0.9350.90
247_V257_L0.9340.90
345_N349_A0.9330.90
422_V431_V0.9310.90
431_V436_A0.9300.90
404_S409_S0.9270.90
577_V585_S0.9240.89
119_Q143_N0.9240.89
358_R362_K0.9230.89
358_R361_L0.9230.89
252_P256_A0.9220.89
364_G410_F0.9200.89
473_V555_L0.9180.89
237_M290_G0.9160.89
40_L144_M0.9140.89
266_T270_G0.9080.89
63_M101_V0.9060.89
430_A435_S0.9050.88
432_M548_G0.9020.88
131_V138_V0.9020.88
186_P210_S0.9000.88
578_G582_E0.8980.88
471_V544_I0.8970.88
134_M586_A0.8940.88
132_I160_G0.8910.88
240_Q261_A0.8910.88
522_A546_V0.8890.88
498_L521_S0.8880.88
82_Q218_P0.8870.87
241_L264_Q0.8870.87
131_V583_L0.8850.87
452_E572_L0.8850.87
272_G278_I0.8850.87
333_M410_F0.8840.87
174_V261_A0.8830.87
53_Q56_D0.8800.87
124_L141_S0.8790.87
93_K97_E0.8770.87
297_T356_L0.8740.87
341_P405_N0.8700.86
445_E554_T0.8690.86
55_E79_S0.8680.86
196_L210_S0.8680.86
461_F493_P0.8670.86
286_V371_N0.8660.86
359_E411_E0.8660.86
477_Q488_H0.8640.86
587_L591_L0.8620.86
88_P104_V0.8600.86
92_R104_V0.8600.86
335_R342_A0.8580.86
330_V365_L0.8560.86
276_M280_K0.8560.86
484_M488_H0.8520.85
560_A564_A0.8490.85
474_V477_Q0.8480.85
54_P63_M0.8460.85
441_N444_I0.8440.85
84_Y178_S0.8430.85
178_S220_T0.8430.85
189_E206_A0.8420.85
555_L558_D0.8390.84
71_I136_A0.8360.84
362_K399_E0.8340.84
152_G175_F0.8340.84
256_A260_A0.8340.84
253_L256_A0.8340.84
112_C116_T0.8320.84
532_G569_I0.8320.84
328_D551_G0.8310.84
67_N101_V0.8310.84
491_M512_L0.8290.84
100_A262_A0.8280.84
586_A590_K0.8260.83
190_K345_N0.8260.83
433_K437_V0.8250.83
281_M371_N0.8250.83
83_P178_S0.8220.83
182_A248_H0.8220.83
47_H196_L0.8210.83
239_M281_M0.8200.83
268_M373_V0.8190.83
371_N376_F0.8180.83
350_A404_S0.8170.83
233_V294_L0.8160.83
357_V366_L0.8160.83
466_L540_D0.8130.82
59_S62_S0.8080.82
279_G315_G0.8040.82
264_Q276_M0.8020.82
430_A436_A0.8010.82
362_K379_S0.8000.81
192_R196_L0.7990.81
149_L176_V0.7980.81
262_A265_V0.7970.81
430_A526_T0.7970.81
111_M138_V0.7950.81
384_E398_A0.7930.81
378_L383_L0.7930.81
361_L364_G0.7920.81
572_L578_G0.7910.81
293_A353_V0.7900.81
136_A161_L0.7900.81
586_A600_C0.7900.81
65_R97_E0.7890.81
545_R552_E0.7870.80
37_R40_L0.7810.80
94_A259_A0.7800.80
486_E489_K0.7780.80
507_V538_V0.7770.80
461_F496_V0.7750.79
287_V316_I0.7750.79
335_R408_A0.7750.79
168_F171_L0.7740.79
558_D564_A0.7720.79
72_T84_Y0.7710.79
379_S383_L0.7690.79
581_R585_S0.7690.79
192_R195_Q0.7680.79
162_T282_I0.7670.79
444_I471_V0.7660.79
329_V365_L0.7660.79
266_T269_T0.7650.78
324_S421_K0.7640.78
312_R317_Q0.7630.78
138_V583_L0.7630.78
173_A278_I0.7590.78
350_A401_S0.7580.78
70_I92_R0.7550.78
98_A262_A0.7550.78
232_M245_S0.7550.78
232_M297_T0.7530.77
65_R101_V0.7530.77
473_V525_V0.7510.77
110_A157_I0.7500.77
347_F407_I0.7490.77
166_L287_V0.7480.77
95_L149_L0.7470.77
94_A98_A0.7460.77
111_M125_S0.7460.77
371_N381_Y0.7450.77
276_M381_Y0.7450.77
449_V465_L0.7450.77
429_R534_L0.7440.77
334_A356_L0.7440.77
476_H536_A0.7420.76
204_R208_L0.7410.76
36_H141_S0.7410.76
36_H40_L0.7400.76
467_D502_F0.7400.76
243_G348_Q0.7400.76
466_L470_C0.7390.76
80_A112_C0.7390.76
120_D579_T0.7350.76
285_K370_V0.7350.76
522_A525_V0.7340.76
292_V365_L0.7330.75
427_L475_R0.7320.75
525_V535_L0.7310.75
70_I91_I0.7300.75
326_L329_V0.7290.75
283_D286_V0.7270.75
272_G276_M0.7260.75
516_S521_S0.7260.75
152_G161_L0.7260.75
166_L286_V0.7260.75
84_Y104_V0.7200.74
84_Y88_P0.7130.73
70_I148_A0.7130.73
177_P231_Q0.7120.73
423_L430_A0.7090.73
73_S152_G0.7090.73
177_P254_R0.7090.73
224_Y297_T0.7080.73
371_N374_A0.7070.73
286_V316_I0.7060.73
39_Q144_M0.7060.73
66_N100_A0.7060.73
296_A333_M0.7060.73
265_V269_T0.7050.73
76_D104_V0.7040.72
41_A67_N0.7040.72
592_S599_T0.7040.72
547_N552_E0.7030.72
69_A145_F0.7000.72
287_V318_I0.6980.72
186_P209_E0.6930.71
268_M281_M0.6920.71
170_H278_I0.6920.71
148_A173_A0.6890.71
185_L188_K0.6880.71
304_T323_F0.6880.71
190_K343_D0.6880.71
369_D379_S0.6880.71
91_I151_L0.6830.70
365_L410_F0.6820.70
279_G581_R0.6820.70
42_C64_L0.6810.70
368_E383_L0.6810.70
233_V307_L0.6800.70
380_R384_E0.6790.70
69_A105_A0.6790.70
427_L554_T0.6790.70
452_E540_D0.6790.70
291_I326_L0.6790.70
95_L102_G0.6780.70
166_L278_I0.6770.70
258_T261_A0.6770.70
458_M492_P0.6770.70
255_D259_A0.6750.69
291_I307_L0.6750.69
557_V563_A0.6740.69
59_S63_M0.6740.69
462_E515_A0.6730.69
71_I105_A0.6730.69
558_D562_L0.6730.69
446_A471_V0.6720.69
107_G161_L0.6720.69
288_V369_D0.6720.69
451_F466_L0.6720.69
181_M215_Y0.6720.69
379_S384_E0.6720.69
354_P381_Y0.6710.69
433_K438_P0.6700.69
456_D460_A0.6680.69
549_Q552_E0.6680.69
320_W595_E0.6680.69
429_R432_M0.6670.68
544_I555_L0.6620.68
468_R502_F0.6590.67
531_D593_G0.6590.67
218_P250_D0.6590.67
239_M283_D0.6580.67
580_G585_S0.6570.67
367_H370_V0.6570.67
548_G551_G0.6560.67
281_M372_T0.6560.67
85_E92_R0.6550.67
75_N139_G0.6550.67
447_P545_R0.6540.67
437_V548_G0.6540.67
282_I318_I0.6530.67
191_V195_Q0.6520.67
193_I197_Y0.6510.67
62_S263_R0.6500.66
484_M594_A0.6490.66
328_D421_K0.6490.66
268_M271_N0.6480.66
318_I323_F0.6480.66
447_P471_V0.6470.66
362_K411_E0.6470.66
192_R515_A0.6470.66
437_V441_N0.6460.66
46_A49_F0.6460.66
196_L214_S0.6460.66
476_H568_H0.6460.66
355_V407_I0.6450.66
457_V472_V0.6450.66
292_V360_L0.6450.66
311_A316_I0.6440.66
370_V377_G0.6440.66
73_S110_A0.6440.66
261_A265_V0.6440.66
98_A266_T0.6430.66
421_K432_M0.6420.65
70_I88_P0.6410.65
370_V379_S0.6410.65
236_F366_L0.6410.65
532_G537_K0.6410.65
73_S107_G0.6400.65
312_R599_T0.6400.65
90_I94_A0.6380.65
315_G581_R0.6370.65
95_L265_V0.6360.65
236_F353_V0.6350.65
153_V178_S0.6350.65
286_V314_A0.6340.65
536_A567_P0.6330.64
174_V268_M0.6330.64
239_M286_V0.6330.64
140_L171_L0.6320.64
324_S327_S0.6320.64
304_T431_V0.6300.64
47_H207_L0.6290.64
68_I265_V0.6290.64
283_D370_V0.6280.64
536_A572_L0.6260.64
131_V135_S0.6230.63
279_G314_A0.6230.63
421_K434_T0.6220.63
248_H348_Q0.6210.63
471_V505_A0.6210.63
531_D569_I0.6200.63
530_Y571_D0.6180.63
78_L139_G0.6180.63
77_M139_G0.6180.63
89_E92_R0.6170.62
36_H39_Q0.6170.62
75_N110_A0.6160.62
374_A377_G0.6150.62
233_V237_M0.6150.62
53_Q58_A0.6130.62
576_R579_T0.6130.62
234_V310_M0.6130.62
333_M359_E0.6130.62
333_M408_A0.6120.62
85_E104_V0.6120.62
236_F370_V0.6120.62
342_A406_V0.6110.62
247_V348_Q0.6110.62
183_S222_T0.6110.62
117_Q223_F0.6110.62
186_P202_V0.6110.62
48_G144_M0.6100.62
438_P441_N0.6090.61
539_R569_I0.6090.61
166_L279_G0.6090.61
259_A263_R0.6080.61
510_G598_A0.6080.61
198_A462_E0.6070.61
94_A263_R0.6070.61
530_Y591_L0.6060.61
36_H43_G0.6030.61
36_H144_M0.6020.61
543_I555_L0.6010.60
81_H181_M0.5990.60
350_A407_I0.5990.60
449_V468_R0.5990.60
359_E410_F0.5990.60
148_A168_F0.5980.60
243_G354_P0.5980.60
185_L349_A0.5950.60
256_A259_A0.5950.60
460_A465_L0.5930.59
217_A250_D0.5930.59
438_P442_Q0.5920.59
427_L535_L0.5920.59
117_Q225_G0.5920.59
333_M356_L0.5920.59
234_V239_M0.5920.59
222_T337_Y0.5920.59
484_M489_K0.5900.59
324_S424_S0.5900.59
332_L414_F0.5890.59
127_L583_L0.5880.59
171_L278_I0.5870.59
566_E570_P0.5870.59
96_H101_V0.5870.59
81_H112_C0.5860.58
405_N408_A0.5860.58
432_M437_V0.5860.58
267_R276_M0.5840.58
87_Y151_L0.5840.58
450_V555_L0.5830.58
557_V564_A0.5830.58
257_L261_A0.5830.58
264_Q373_V0.5820.58
495_G515_A0.5810.58
199_E500_R0.5800.58
297_T347_F0.5800.58
564_A570_P0.5790.58
260_A264_Q0.5770.57
459_P465_L0.5770.57
87_Y94_A0.5770.57
120_D141_S0.5770.57
301_T524_H0.5760.57
295_L327_S0.5760.57
427_L555_L0.5750.57
571_D576_R0.5750.57
43_G46_A0.5740.57
254_R257_L0.5740.57
332_L418_G0.5730.57
374_A380_R0.5730.57
232_M344_I0.5730.57
531_D595_E0.5730.57
447_P555_L0.5720.57
80_A157_I0.5720.57
113_D122_M0.5720.57
205_M209_E0.5720.57
292_V367_H0.5720.57
491_M494_L0.5720.57
339_N436_A0.5710.57
222_T343_D0.5700.56
336_L347_F0.5700.56
53_Q63_M0.5700.56
193_I202_V0.5690.56
572_L577_V0.5690.56
364_G368_E0.5690.56
432_M522_A0.5670.56
72_T225_G0.5670.56
554_T557_V0.5660.56
304_T422_V0.5660.56
582_E585_S0.5650.56
136_A150_F0.5650.56
324_S417_H0.5640.56
69_A139_G0.5640.56
113_D121_G0.5630.55
251_S348_Q0.5620.55
405_N412_Q0.5620.55
417_H442_Q0.5610.55
426_N534_L0.5590.55
383_L399_E0.5580.55
282_I310_M0.5580.55
165_A175_F0.5580.55
66_N266_T0.5550.54
444_I505_A0.5540.54
505_A519_V0.5540.54
175_F244_S0.5540.54
69_A104_V0.5530.54
152_G215_Y0.5510.54
91_I265_V0.5510.54
71_I110_A0.5510.54
56_D101_V0.5510.54
135_S139_G0.5510.54
460_A540_D0.5510.54
114_G121_G0.5510.54
61_K260_A0.5500.54
441_N519_V0.5500.54
362_K368_E0.5500.54
202_V210_S0.5490.54
355_V404_S0.5490.54
444_I519_V0.5490.54
116_T119_Q0.5480.53
447_P556_L0.5480.53
432_M436_A0.5480.53
141_S144_M0.5470.53
87_Y90_I0.5460.53
432_M435_S0.5460.53
291_I319_N0.5450.53
265_V268_M0.5450.53
546_V553_L0.5430.53
294_L299_G0.5420.53
515_A521_S0.5420.53
368_E384_E0.5420.53
359_E409_S0.5420.53
435_S438_P0.5410.53
456_D465_L0.5410.53
75_N106_G0.5400.52
529_A535_L0.5400.52
360_L364_G0.5400.52
91_I95_L0.5390.52
92_R102_G0.5390.52
49_F118_G0.5380.52
585_S590_K0.5370.52
74_Y88_P0.5360.52
372_T381_Y0.5360.52
189_E341_P0.5360.52
577_V582_E0.5350.52
400_K404_S0.5350.52
173_A239_M0.5340.52
239_M314_A0.5340.52
106_G109_P0.5340.52
177_P240_Q0.5330.52
360_L366_L0.5330.52
217_A251_S0.5310.51
231_Q245_S0.5300.51
171_L473_V0.5300.51
458_M462_E0.5290.51
56_D82_Q0.5290.51
128_S138_V0.5290.51
383_L398_A0.5280.51
45_L198_A0.5270.51
140_L145_F0.5260.51
61_K263_R0.5250.50
335_R405_N0.5240.50
421_K548_G0.5230.50
231_Q254_R0.5230.50
268_M280_K0.5230.50
559_E562_L0.5220.50
319_N325_D0.5210.50
167_S313_A0.5210.50
95_L266_T0.5210.50
283_D316_I0.5210.50
196_L199_E0.5210.50
191_V194_R0.5210.50
70_I104_V0.5200.50
318_I321_D0.5200.50
71_I106_G0.5200.50
323_F422_V0.5200.50
56_D92_R0.5190.50
474_V516_S0.5190.50
47_H50_A0.5180.50
206_A209_E0.5170.49
539_R555_L0.5170.49
248_H345_N0.5160.49
362_K410_F0.5150.49
118_G122_M0.5150.49
183_S346_H0.5140.49
319_N595_E0.5140.49
162_T237_M0.5140.49
58_A63_M0.5130.49
243_G247_V0.5130.49
335_R414_F0.5130.49
439_V442_Q0.5130.49
83_P249_P0.5120.49
186_P191_V0.5120.49
71_I107_G0.5120.49
116_T125_S0.5110.49
448_A471_V0.5110.49
451_F540_D0.5110.49
248_H251_S0.5110.49
591_L598_A0.5100.48
285_K325_D0.5090.48
567_P570_P0.5090.48
76_D82_Q0.5080.48
308_V526_T0.5080.48
260_A267_R0.5080.48
106_G151_L0.5080.48
356_L407_I0.5070.48
444_I503_K0.5060.48
476_H569_I0.5060.48
370_V381_Y0.5030.48
244_S254_R0.5030.48
423_L432_M0.5030.48
41_A119_Q0.5020.47
287_V290_G0.5020.47
327_S419_G0.5010.47
333_M360_L0.5010.47
233_V245_S0.5000.47
477_Q484_M0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gp4A 2 0.8541 100 0.068 Contact Map
3rfqA 5 0.2189 76.9 0.981 Contact Map
2pcnA 3 0.2338 69.8 0.982 Contact Map
2is8A 3 0.2355 62 0.983 Contact Map
4xcwA 3 0.257 60.3 0.984 Contact Map
2c5qA 3 0.3118 50.9 0.984 Contact Map
1nxjA 3 0.2255 47.4 0.985 Contact Map
2mpuA 1 0.1459 47.3 0.985 Contact Map
4lhbA 4 0.2222 45.8 0.985 Contact Map
1zymA 2 0.3715 44.3 0.985 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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