GREMLIN Database
YJJQ - Putative transcription factor YjjQ
UniProt: P0ADD7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12593
Length: 241 (196)
Sequences: 67093 (46296)
Seq/√Len: 3306.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
19_Q36_I3.8021.00
19_Q38_S3.2621.00
23_K36_I3.2581.00
12_I43_D2.7551.00
44_L75_S2.6371.00
41_A63_S2.6111.00
64_E75_S2.3781.00
39_A63_S2.3771.00
35_I52_S2.2981.00
48_Q79_Q2.2871.00
25_V115_I2.2151.00
8_N35_I2.1621.00
23_K27_R2.1281.00
40_S64_E2.0771.00
29_H119_V2.0691.00
35_I46_L2.0251.00
97_A117_N2.0071.00
157_S160_K1.9931.00
8_N33_Y1.9491.00
37_S46_L1.9451.00
183_K186_S1.9211.00
38_S42_E1.8671.00
60_A91_R1.8401.00
35_I50_R1.8401.00
31_P123_R1.8301.00
39_A42_E1.7951.00
94_Y114_P1.7881.00
73_Y85_W1.7621.00
87_F100_L1.7541.00
77_I106_A1.7491.00
46_L50_R1.7121.00
164_L177_L1.7001.00
57_A72_H1.6421.00
26_M122_V1.6201.00
163_R167_K1.6181.00
75_S79_Q1.6001.00
87_F105_T1.5831.00
10_I37_S1.5761.00
107_T121_T1.5691.00
91_R96_Q1.5431.00
40_S72_H1.5291.00
7_K126_N1.5261.00
64_E71_E1.4971.00
46_L49_L1.4971.00
170_G173_Q1.4971.00
16_P38_S1.4841.00
86_V125_G1.4791.00
54_L122_V1.4761.00
55_V83_I1.4701.00
188_Q191_S1.4601.00
41_A64_E1.4351.00
47_L76_L1.4231.00
171_I186_S1.4181.00
65_D71_E1.4091.00
75_S78_S1.3781.00
71_E74_Y1.3531.00
74_Y103_C1.3221.00
80_Y83_I1.3211.00
44_L72_H1.3021.00
12_I61_G1.2941.00
73_Y87_F1.2891.00
158_E195_R1.2751.00
59_L70_C1.2701.00
144_T151_S1.2661.00
106_A128_H1.2431.00
45_T49_L1.2261.00
29_H123_R1.2251.00
119_V123_R1.2131.00
65_D70_C1.2111.00
13_S19_Q1.2071.00
173_Q177_L1.2061.00
93_W96_Q1.2021.00
42_E45_T1.1971.00
44_L64_E1.1941.00
59_L87_F1.1741.00
57_A73_Y1.1681.00
8_N50_R1.1661.00
42_E46_L1.1631.00
102_M123_R1.1611.00
46_L52_S1.1431.00
187_A190_N1.1361.00
70_C99_E1.1261.00
54_L126_N1.1251.00
10_I52_S1.1231.00
10_I43_D1.1211.00
37_S43_D1.1171.00
169_W177_L1.1141.00
41_A45_T1.1001.00
97_A110_S1.0891.00
14_K58_D1.0861.00
137_T140_A1.0671.00
159_R163_R1.0651.00
117_N120_K1.0561.00
95_S99_E1.0561.00
10_I46_L1.0511.00
160_K163_R1.0491.00
146_D151_S1.0381.00
164_L168_G1.0351.00
70_C100_L1.0341.00
172_N182_N1.0341.00
125_G128_H1.0221.00
37_S42_E1.0121.00
70_C103_C1.0071.00
94_Y98_V1.0001.00
120_K124_S0.9901.00
99_E103_C0.9881.00
44_L48_Q0.9821.00
156_L160_K0.9731.00
183_K187_A0.9651.00
43_D47_L0.9641.00
98_V102_M0.9321.00
11_V22_L0.9311.00
22_L88_M0.9311.00
74_Y99_E0.9301.00
10_I35_I0.9271.00
17_V21_G0.9271.00
55_V76_L0.9251.00
124_S129_A0.9171.00
106_A125_G0.8981.00
16_P20_A0.8981.00
47_L80_Y0.8971.00
43_D72_H0.8961.00
170_G174_I0.8941.00
143_E160_K0.8901.00
92_S110_S0.8851.00
20_A36_I0.8831.00
12_I55_V0.8811.00
73_Y103_C0.8761.00
24_E28_T0.8711.00
45_T48_Q0.8711.00
59_L65_D0.8651.00
10_I47_L0.8581.00
84_H106_A0.8501.00
98_V116_E0.8491.00
189_K193_M0.8471.00
184_T188_Q0.8471.00
56_I88_M0.8391.00
12_I37_S0.8391.00
191_S194_R0.8361.00
94_Y97_A0.8341.00
124_S127_T0.8311.00
183_K190_N0.8291.00
57_A87_F0.8261.00
73_Y105_T0.8181.00
71_E75_S0.8181.00
16_P19_Q0.8061.00
164_L174_I0.8041.00
57_A85_W0.8031.00
96_Q99_E0.8021.00
47_L52_S0.7981.00
182_N186_S0.7981.00
101_L121_T0.7961.00
165_L189_K0.7961.00
8_N53_G0.7931.00
202_A205_Y0.7911.00
99_E102_M0.7851.00
155_T195_R0.7841.00
74_Y78_S0.7821.00
56_I118_L0.7821.00
61_G72_H0.7811.00
95_S116_E0.7811.00
190_N194_R0.7781.00
115_I119_V0.7741.00
174_I178_L0.7741.00
9_G31_P0.7731.00
23_K34_E0.7691.00
172_N176_S0.7631.00
20_A23_K0.7621.00
7_K130_E0.7611.00
60_A90_S0.7601.00
197_A200_S0.7571.00
22_L118_L0.7541.00
31_P119_V0.7471.00
82_E131_R0.7451.00
8_N52_S0.7451.00
117_N121_T0.7381.00
146_D149_Y0.7381.00
88_M113_E0.7351.00
187_A191_S0.7341.00
9_G54_L0.7311.00
55_V85_W0.7291.00
72_H76_L0.7281.00
20_A24_E0.7281.00
64_E72_H0.7261.00
51_R80_Y0.7261.00
157_S188_Q0.7201.00
179_K182_N0.7161.00
160_K164_L0.7161.00
143_E159_R0.7151.00
47_L83_I0.7111.00
47_L55_V0.7091.00
59_L96_Q0.6991.00
59_L91_R0.6981.00
12_I72_H0.6921.00
76_L81_R0.6911.00
102_M120_K0.6881.00
13_S61_G0.6861.00
175_A178_L0.6851.00
198_I203_E0.6841.00
40_S63_S0.6831.00
97_A114_P0.6791.00
9_G26_M0.6761.00
135_M139_P0.6741.00
173_Q176_S0.6731.00
203_E206_A0.6711.00
19_Q23_K0.6691.00
21_G25_V0.6681.00
48_Q80_Y0.6641.00
86_V107_T0.6631.00
114_P117_N0.6631.00
136_L139_P0.6601.00
164_L167_K0.6591.00
180_K185_I0.6571.00
199_H203_E0.6561.00
193_M198_I0.6521.00
94_Y116_E0.6491.00
200_S203_E0.6481.00
172_N175_A0.6481.00
11_V23_K0.6461.00
171_I182_N0.6441.00
40_S44_L0.6431.00
89_V111_D0.6361.00
116_E120_K0.6311.00
58_D111_D0.6291.00
167_K177_L0.6271.00
25_V119_V0.6241.00
48_Q75_S0.6211.00
44_L47_L0.6201.00
42_E63_S0.6201.00
59_L100_L0.6171.00
169_W173_Q0.6171.00
15_I90_S0.6171.00
86_V121_T0.6161.00
113_E118_L0.6121.00
44_L79_Q0.6071.00
155_T158_E0.6061.00
186_S189_K0.6061.00
171_I175_A0.6031.00
100_L105_T0.5991.00
126_N129_A0.5991.00
11_V36_I0.5971.00
14_K89_V0.5951.00
147_F150_R0.5951.00
7_K31_P0.5931.00
136_L140_A0.5921.00
51_R81_R0.5921.00
147_F197_A0.5891.00
18_M113_E0.5881.00
31_P126_N0.5831.00
158_E191_S0.5791.00
164_L178_L0.5781.00
84_H126_N0.5781.00
89_V108_L0.5781.00
199_H202_A0.5771.00
189_K201_N0.5761.00
7_K53_G0.5751.00
11_V34_E0.5741.00
163_R166_G0.5681.00
13_S111_D0.5671.00
113_E117_N0.5651.00
164_L169_W0.5641.00
40_S61_G0.5611.00
202_A206_A0.5591.00
144_T147_F0.5591.00
56_I122_V0.5591.00
70_C96_Q0.5581.00
21_G24_E0.5551.00
73_Y77_I0.5531.00
162_L192_A0.5521.00
25_V29_H0.5511.00
89_V97_A0.5491.00
77_I84_H0.5471.00
197_A203_E0.5451.00
27_R33_Y0.5371.00
9_G122_V0.5361.00
120_K123_R0.5331.00
82_E132_I0.5331.00
145_H152_V0.5321.00
121_T125_G0.5311.00
162_L204_M0.5291.00
56_I86_V0.5291.00
77_I83_I0.5271.00
100_L108_L0.5241.00
129_A133_S0.5221.00
98_V101_L0.5191.00
95_S98_V0.5191.00
15_I18_M0.5181.00
76_L85_W0.5181.00
135_M138_S0.5161.00
107_T125_G0.5151.00
54_L125_G0.5131.00
124_S128_H0.5021.00
24_E27_R0.5011.00
161_V188_Q0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4gvpA 1 0.8589 100 0.282 Contact Map
3c3wA 2 0.8589 100 0.304 Contact Map
1a04A 1 0.8382 100 0.307 Contact Map
1yioA 1 0.8216 100 0.309 Contact Map
4ldzA 2 0.8133 100 0.318 Contact Map
3kloA 2 0.8672 100 0.325 Contact Map
4hyeA 2 0.8257 100 0.344 Contact Map
3q9sA 1 0.8216 100 0.347 Contact Map
1ys7A 2 0.8631 100 0.349 Contact Map
4b09A 2 0.8257 100 0.364 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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